4K2PA

The structure of a quintuple mutant of the tiam1 ph-cc-ex domain
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
238
structure length
238
Chain Sequence
TVRKAGALAVKNFLVHKKNKKVESATRRKWKHYWVSLKGCTLFFYESDGRSGIDHNSIPKHAVWVENSIVQAVPEHPKKDFVFCLSNSLGDAFLFQTTSQTELENWITAIHSACATAVARHHHKEDTLRLLKSEIKKLEQKIDMDEKLKKMGELQLSSVTDSKAAATILDQIFVWEQNLEQFQMDLFRFRCYLASLQGGELPNPKRLLAFASRPTKVAMGRLGIFSVSSFHALVAART
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title High-resolution structure of the Tiam1 PHn-CC-Ex domain.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Signaling protein
molecule keywords T-lymphoma invasion and metastasis-inducing protein 1
total genus 78
structure length 238
sequence length 238
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-04-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF18385 Tiam_CC_Ex T-lymphoma invasion and metastasis CC-Ex domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 4k2pA01
3ML4A 1WG7A 2G35A 1IRSA 4CHMA 1NU2A 5D3XA 2H7EA 2DHIA 2EMTA 3MPXA 1MK7B 2D9YA 4CHJA 1Y19B 1FB8A 1EF1A 3D8FA 1W1HA 2K00A 3SNHA 2YS3A 2UZSA 1U27A 2EC1A 1MKEA 5HE1A 2Y8GA 3NSUA 2DA0A 3QIJA 2Y8FA 1M7EA 5KQ4A 4HAYB 2UVMA 3T06A 1V61A 2GJYA 5FI1A 3AU5A 3GYPA 4EKUA 2XQNM 1WJMA 3O96A 2GCJA 1QQGA 4IFSA 5DHFB 4A6FB 2YRYA 2YF0A 4KHBB 2I1JA 1LW3A 1K5DB 4HAUB 1OQNA 4IOYX 1I7AA 1V89A 4YONA 1BWNA 1X86A 3DXEA 3HQCA 1MIZB 2MKRA 5C5BB 3D8EA 2DTCA 2W2XD 2COFA 1K5GB 4ZRKA 4PNKA 1UPQA 2NZ8B 1PMSA 4GXBA 1GC7A 4HHVA 4HB3B 5CLQB 1NTYA 2RSGA 5D3VA 4MK0A 2J0JA 3F5RA 2L1CA 2I5FA 4CYEA 4HAZB 2AEHA 3U8ZA 3PVUA 4A6HA 3M1IB 4GPTB 3ULBA 1RRPB 1KZGA 5LOPB 1H10A 1H4RA 2M38A 5DH9B 1UNPA 5D3WA 2QKLA 1WI1A 5JHGA 1XR0B 4P7IA 4Z2MB 4KHOA 4WJ7A 3SUZA 1TQZA 4HB2B 3QBVB 3ODWA 4K2PA 4HAVB 4ZRIA 2DX1A 1U29A 2RNRB 4EMOA 2AL6A 1X11A 2IFSA 3KRWA 3TCAA 4A5KA 1WGQA 1DROA 1B55A 3P6AA 2BCJA 2VKIA 2CRFA 2Z0QA 3AJ4A 2LOXA 3X23A 4F7HA 2P8VA 3SV1A 1P3RA 1W1DA 2YT0A 2J0KA 2GS0A 4F7UP 4YL8A 3ZVRA 2L2IA 1PLSA 1MAIA 2Z0OA 5C6RA 3A8QA 3FSSA 5C79A 3PEGA 3DXCA 1FHXA 2IYBA 1XODA 4GMVA 3U7DA 5JLJB 2FJLA 2COCA 2DLWA 2YS5A 1MK9B 5HE2A 2K2UA 3PZDA 3WYFB 4BBKA 1WGUA 3ODOA 1FAOA 1U2BA 1TXDA 2DHJA 4DXAB 4WSFA 2J0MA 1X1FA 3IVFA 4NSWA 1LB1A 2DYNA 1Q67A 3TVVA 2Z0PA 3PVLA 4KVGB 1FHOA 3MDBC 5EFXA 2YS1A 2VSZA 4IAPA 1U5FA 4NY0A 1P6SA 2CY4A 1DDWA 4HDOA 2DX5A 3GYOA 1MPHA 3KZ1A 3BJIA 3RCPA 4WVFB 3SYXA 2LULA 2EMSA 3V5WA 1W1GA 5L81A 5J3QA 5DI9B 4A6KA 1RJ2A 1OY2A 1XD4A 2Y7BA 3VOQA 2KGXB 1U5DA 3TFMA 1J0WA 3TO1A 2D9ZA 3AU4A 4A6FA 2X18A 3CXBB 5J3YA 3LJUX 2H7DA 3KRXA 2P0HA 2JP2A 5KCVA 4PQ0A 5CLLB 4HAWB 1WJ1A 2YT1A 4HAXB 1UPRA 1EAZA 3A98B 2V76A 1WVHA 2MFQA 1X1GA 2HTHB 2DFKA 2YSZA 3PVWA 1NI2A 1PFJA 2D10A 3D8DA 2RUKB 5JHHA 3KY9A 2E2XA 1ZM0A 2RGNB 3HW2B 2R09A 3PSCA 2Q13A 4MT7A 2ADZA 4KHAA 2CODA 2DKPA 3ULCA 2OTXA 1N3HA 2D9WA 4Y94A 5D27A 5DHAB 1FHWA 4TYZA 1AWEA 1XKEA 3N7CA 5FI0A 1V88A 2UZRA 2LYDA 2D2QA 3FEHA 1ZVRA 2KCJA 1FGZA 3SO6A 4MY6A 1X05A 1E5WA 1BAKA 2OQBA 1KI1B 4HB4B 2LOZA 2NMBA 2ROVA 4K81A 1BTNA 4D0NB 1J19A 5HE0A 4GZUA 2RVBB 2MWNB 2DYQA 2COAA 1UEFA 4K17A 3G9WA 5HE3A 4K2OA 4GN1A 1Z87A 5C5BA 2YVCA 1QC6A 1AQCA 3CIKA 4L6EA 3BINA 2P0DA 1GC6A 4DX90 1M7RA 2DKQA 2VRWB 4XWXA 2R0DA 4HDQA 3QWMA 1UNQA 3F0WA 1V5MA 3FM8C 2DN6A 2N0YA 2W2WA 3ZDTA 4F7GA 2N23A 1DYNA 1DDVA 1TJ6A 1UNRA 2PZ1A 1Y5OA 2CY5A 2CAYA 1NTVA 3TW1A 3P7ZA 1SHCA 5D3YA 3WA0A 1FOEA 4B6HA 1I2HA 3DXDA 3A8PA 4EJNA 2D9XA 2K2JA 5JP4A 1V5UA 2M14A 2GCLA 4C0AA 2ELBA 2ROZB 4ZRJA 4Z2NA 5C16A 4DBBA 3UZTA 2P0FA 5J3TA 1FGYA 1EVHA 2KUPA 5KQ1A 5LONB 4DX8A 1U5GA 1ZC3B 2EJ8A 1KZ7A 4KAXB 1ISNA 4HATB 1SGHA 2DHKA 1ZC4B 2J59M 1P5TA 3HK0A 5DIFB 4HB0B 2I1KA 2W2XC 1GG3A 1XCGA 3OANA 3PP2A 2ZPYA 1DDMA 2ELAA 2LKOA 1ZSQA 4GMXB 2MDXA 1U5EA 3KSYA 1MIXA 4H8SA 4TKNA 3ODXA 3PG7A 1OMWA 5GOWB 1V5PA 1EGXA 1XX0A 2D9VA 3VIAA 2LG1A 2RLOA 2I5CA 2D4QA 2QKMA 1BTKA 2D11A 1DBHA 2HE7A
chains in the Genus database with same CATH superfamily
3ML4A 4KHBA 1WG7A 2G35A 1IRSA 4CHMA 1NU2A 5D3XA 2H7EA 2DHIA 2EMTA 3MPXA 1MK7B 2D9YA 4CHJA 1Y19B 1FB8A 1EF1A 3D8FA 1W1HA 3FVCA 2K00A 5M4YB 3SNHA 2YS3A 2UZSA 1U27A 2EC1A 1MKEA 5HE1A 3A58A 2Y8GA 3NSUA 4DIXA 2DA0A 4OSNA 3QIJA 2Y8FA 1T77A 1M7EA 5KQ4A 4HAYB 2UVMA 3T06A 1V61A 2GJYA 5FI1A 2KIEA 3AU5A 3GYPA 4EKUA 2XQNM 1WJMA 3O96A 2GCJA 1QQGA 4QJ3B 4IFSA 5DHFB 4QXAB 4A6FB 2YRYA 2YF0A 4KHBB 2I1JA 1LW3A 1K5DB 4HAUB 2Z13A 1OQNA 4IOYX 1I7AA 1V89A 4YONA 1BWNA 2Z4DA 3B77A 1X86A 3DXEA 3HQCA 1MIZB 2MKRA 3NWDA 5C5BB 3D8EA 2DTCA 2W2XD 2COFA 2Z59A 1K5GB 4ZRKA 4PNKA 1UPQA 2NZ8B 1PMSA 4GXBA 1GC7A 4HHVA 4HB3B 5CLQB 1NTYA 2RSGA 5D3VA 4MK0A 2J0JA 3F5RA 2L1CA 2I5FA 4CYEA 4HAZB 2AEHA 3U8ZA 3PVUA 2FJUB 4A6HA 3M1IB 4GPTB 3ULBA 1RRPB 1KZGA 5LOPB 1H10A 1H4RA 2M38A 5IRSA 5DH9B 1UNPA 5D3WA 2QKLA 4D6WA 1WI1A 5JHGA 1XR0B 4P7IA 4Z2MB 4KHOA 4WJ7A 3SUZA 1TQZA 4HB2B 3QBVB 3ODWA 4K2PA 4HAVB 4ZRIA 2DX1A 1U29A 2RNRB 4EMOA 2AL6A 1X11A 2IFSA 3KRWA 3TCAA 4A5KA 1WGQA 1DROA 1B55A 3P6AA 2BCJA 2VKIA 2CRFA 2Z0QA 3AJ4A 2LOXA 3X23A 4F7HA 2P8VA 3SV1A 1P3RA 1W1DA 2YT0A 2J0KA 2GS0A 4F7UP 4YL8A 3ZVRA 2L2IA 1PLSA 1MAIA 2Z0OA 5C6RA 5I2SA 3A8QA 3FSSA 5C79A 3PEGA 3DXCA 1FHXA 2IYBA 1XODA 4GMVA 3U7DA 5JLJB 2FJLA 2COCA 2DLWA 2YS5A 1MK9B 5HE2A 2K2UA 3PZDA 3WYFB 4BBKA 1WGUA 3ODOA 4GOUA 1FAOA 1U2BA 1TXDA 2DHJA 4DXAB 4WSFA 2J0MA 1X1FA 3IVFA 4NSWA 1LB1A 2DYNA 1Q67A 3TVVA 2Z0PA 3PVLA 4KVGB 5LG4B 1FHOA 3MDBC 5EFXA 2YS1A 2VSZA 2Z14A 2KUQA 4IAPA 1U5FA 4NY0A 1P6SA 2CY4A 1DDWA 4HDOA 2DX5A 3GYOA 1MPHA 3KZ1A 3BJIA 4L1RA 3RCPA 4WVFB 3SYXA 2LULA 2EMSA 3V5WA 1W1GA 2K8EA 5L81A 5J3QA 5DI9B 4A6KA 1RJ2A 2YT2A 1OY2A 1XD4A 3DCXA 2Y7BA 3VOQA 2KGXB 1U5DA 3NWAA 3TFMA 3U12A 1J0WA 3TO1A 2D9ZA 3AU4A 3NWFA 4A6FA 2X18A 4QJ4B 3CXBB 5J3YA 3LJUX 1ZYIA 2H7DA 3KRXA 2P0HA 2JP2A 5KCVA 4PQ0A 5CLLB 4HAWB 1WJ1A 2YT1A 2NBVA 4HAXB 1UPRA 1EAZA 3A98B 2V76A 1WVHA 2MFQA 1X1GA 2HTHB 2DFKA 2YSZA 3PVWA 1NI2A 1PFJA 2D10A 3D8DA 2RUKB 5JHHA 3KY9A 2E2XA 1ZM0A 1MI1A 2RGNB 3HW2B 2R09A 4HSIA 3PSCA 2Q13A 4MT7A 2ADZA 2RRFA 4KHAA 2CODA 2DKPA 3ULCA 4QJ5B 2OTXA 1N3HA 2D9WA 2GUMA 4Y94A 5D27A 2ZKMX 5DHAB 1FHWA 4TYZA 1AWEA 1XKEA 3N7CA 5FI0A 1V88A 2UZRA 2LYDA 2D2QA 3FEHA 1ZVRA 2KCJA 1FGZA 3SO6A 5I2MA 4MY6A 1X05A 1E5WA 1BAKA 2OQBA 1KI1B 4HB4B 2LOZA 2NMBA 2ROVA 4K81A 1BTNA 4D0NB 1J19A 5HE0A 4GZUA 2RVBB 2MWNB 3OHMB 2DYQA 2COAA 1UEFA 4K17A 3G9WA 5HE3A 4K2OA 4GN1A 1Z87A 2KIGA 5C5BA 2YVCA 1QC6A 1AQCA 3CIKA 4L6EA 3BINA 2P0DA 1GC6A 4DX90 1M7RA 2DKQA 2VRWB 4XWXA 2R0DA 4HDQA 3QWMA 1UNQA 3F0WA 1V5MA 3FM8C 2R2YA 2DN6A 2N0YA 2KR0A 2W2WA 3ZDTA 4F7GA 2N23A 1DYNA 1DDVA 1TJ6A 1UNRA 2PZ1A 1Y5OA 2CY5A 2CAYA 1NTVA 3TW1A 3P7ZA 4CSQA 1SHCA 5D3YA 3WA0A 1FOEA 4B6HA 1I2HA 3DXDA 3A8PA 4EJNA 2D9XA 2K2JA 5JP4A 1V5UA 2M14A 3HIEA 2GCLA 4C0AA 2ELBA 2ROZB 3NW8A 4ZRJA 4Z2NA 5C16A 4DBBA 3UZTA 2P0FA 5J3TA 1FGYA 1EVHA 2KUPA 5KQ1A 5LONB 4DX8A 1U5GA 1ZC3B 2EJ8A 1KZ7A 4KAXB 1ISNA 4HATB 2K49A 1SGHA 2DHKA 1ZC4B 2J59M 1P5TA 3HK0A 5DIFB 4HB0B 2I1KA 2W2XC 1GG3A 1XCGA 3OANA 3PP2A 2ZPYA 1DDMA 2ELAA 2LKOA 1ZSQA 4GMXB 2MDXA 1U5EA 3KSYA 3HSAA 1MIXA 4H8SA 4TKNA 3ODXA 3PG7A 1OMWA 5GOWB 1V5PA 1EGXA 1XX0A 2D9VA 4GNKB 3VIAA 2LG1A 4OT1A 2RLOA 2I5CA 2D4QA 2QKMA 1BTKA 2D11A 1DBHA 2HE7A
chains in the Genus database with same CATH topology
3ML4A 1WG7A 2G35A 1IRSA 4CHMA 1NU2A 5D3XA 2H7EA 2DHIA 2EMTA 3MPXA 1MK7B 2D9YA 4CHJA 1Y19B 1FB8A 1EF1A 3D8FA 1W1HA 2K00A 3SNHA 2YS3A 2UZSA 1U27A 2EC1A 1MKEA 5HE1A 2Y8GA 3NSUA 2DA0A 3QIJA 2Y8FA 1M7EA 5KQ4A 4HAYB 2UVMA 3T06A 1V61A 2GJYA 5FI1A 3AU5A 3GYPA 4EKUA 2XQNM 1WJMA 3O96A 2GCJA 1QQGA 4IFSA 5DHFB 4A6FB 2YRYA 2YF0A 4KHBB 2I1JA 1LW3A 1K5DB 4HAUB 1OQNA 4IOYX 1I7AA 1V89A 4YONA 1BWNA 1X86A 3DXEA 3HQCA 1MIZB 2MKRA 5C5BB 3D8EA 2DTCA 2W2XD 2COFA 1K5GB 4ZRKA 4PNKA 1UPQA 2NZ8B 1PMSA 4GXBA 1GC7A 4HHVA 4HB3B 5CLQB 1NTYA 2RSGA 5D3VA 4MK0A 2J0JA 3F5RA 2L1CA 2I5FA 4CYEA 4HAZB 2AEHA 3U8ZA 3PVUA 4A6HA 3M1IB 4GPTB 3ULBA 1RRPB 1KZGA 5LOPB 1H10A 1H4RA 2M38A 5DH9B 1UNPA 5D3WA 2QKLA 1WI1A 5JHGA 1XR0B 4P7IA 4Z2MB 4KHOA 4WJ7A 3SUZA 1TQZA 4HB2B 3QBVB 3ODWA 4K2PA 4HAVB 4ZRIA 2DX1A 1U29A 2RNRB 4EMOA 2AL6A 1X11A 2IFSA 3KRWA 3TCAA 4A5KA 1WGQA 1DROA 1B55A 3P6AA 2BCJA 2VKIA 2CRFA 2Z0QA 3AJ4A 2LOXA 3X23A 4F7HA 2P8VA 3SV1A 1P3RA 1W1DA 2YT0A 2J0KA 2GS0A 4F7UP 4YL8A 3ZVRA 2L2IA 1PLSA 1MAIA 2Z0OA 5C6RA 3A8QA 3FSSA 5C79A 3PEGA 3DXCA 1FHXA 2IYBA 1XODA 4GMVA 3U7DA 5JLJB 2FJLA 2COCA 2DLWA 2YS5A 1MK9B 5HE2A 2K2UA 3PZDA 3WYFB 4BBKA 1WGUA 3ODOA 1FAOA 1U2BA 1TXDA 2DHJA 4DXAB 4WSFA 2J0MA 1X1FA 3IVFA 4NSWA 1LB1A 2DYNA 1Q67A 3TVVA 2Z0PA 3PVLA 4KVGB 1FHOA 3MDBC 5EFXA 2YS1A 2VSZA 4IAPA 1U5FA 4NY0A 1P6SA 2CY4A 1DDWA 4HDOA 2DX5A 3GYOA 1MPHA 3KZ1A 3BJIA 3RCPA 4WVFB 3SYXA 2LULA 2EMSA 3V5WA 1W1GA 5L81A 5J3QA 5DI9B 4A6KA 1RJ2A 1OY2A 1XD4A 2Y7BA 3VOQA 2KGXB 1U5DA 3TFMA 1J0WA 3TO1A 2D9ZA 3AU4A 4A6FA 2X18A 3CXBB 5J3YA 3LJUX 2H7DA 3KRXA 2P0HA 2JP2A 5KCVA 4PQ0A 5CLLB 4HAWB 1WJ1A 2YT1A 4HAXB 1UPRA 1EAZA 3A98B 2V76A 1WVHA 2MFQA 1X1GA 2HTHB 2DFKA 2YSZA 3PVWA 1NI2A 1PFJA 2D10A 3D8DA 2RUKB 5JHHA 3KY9A 2E2XA 1ZM0A 2RGNB 3HW2B 2R09A 3PSCA 2Q13A 4MT7A 2ADZA 4KHAA 2CODA 2DKPA 3ULCA 2OTXA 1N3HA 2D9WA 4Y94A 5D27A 5DHAB 1FHWA 4TYZA 1AWEA 1XKEA 3N7CA 5FI0A 1V88A 2UZRA 2LYDA 2D2QA 3FEHA 1ZVRA 2KCJA 1FGZA 3SO6A 4MY6A 1X05A 1E5WA 1BAKA 2OQBA 1KI1B 4HB4B 2LOZA 2NMBA 2ROVA 4K81A 1BTNA 4D0NB 1J19A 5HE0A 4GZUA 2RVBB 2MWNB 2DYQA 2COAA 1UEFA 4K17A 3G9WA 5HE3A 4K2OA 4GN1A 1Z87A 5C5BA 2YVCA 1QC6A 1AQCA 3CIKA 4L6EA 3BINA 2P0DA 1GC6A 4DX90 1M7RA 2DKQA 2VRWB 4XWXA 2R0DA 4HDQA 3QWMA 1UNQA 3F0WA 1V5MA 3FM8C 2DN6A 2N0YA 2W2WA 3ZDTA 4F7GA 2N23A 1DYNA 1DDVA 1TJ6A 1UNRA 2PZ1A 1Y5OA 2CY5A 2CAYA 1NTVA 3TW1A 3P7ZA 1SHCA 5D3YA 3WA0A 1FOEA 4B6HA 1I2HA 3DXDA 3A8PA 4EJNA 2D9XA 2K2JA 5JP4A 1V5UA 2M14A 2GCLA 4C0AA 2ELBA 2ROZB 4ZRJA 4Z2NA 5C16A 4DBBA 3UZTA 2P0FA 5J3TA 1FGYA 1EVHA 2KUPA 5KQ1A 5LONB 4DX8A 1U5GA 1ZC3B 2EJ8A 1KZ7A 4KAXB 1ISNA 4HATB 1SGHA 2DHKA 1ZC4B 2J59M 1P5TA 3HK0A 5DIFB 4HB0B 2I1KA 2W2XC 1GG3A 1XCGA 3OANA 3PP2A 2ZPYA 1DDMA 2ELAA 2LKOA 1ZSQA 4GMXB 2MDXA 1U5EA 3KSYA 1MIXA 4H8SA 4TKNA 3ODXA 3PG7A 1OMWA 5GOWB 1V5PA 1EGXA 1XX0A 2D9VA 3VIAA 2LG1A 2RLOA 2I5CA 2D4QA 2QKMA 1BTKA 2D11A 1DBHA 2HE7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ML4 A;  1WG7 A;  2G35 A;  1IRS A;  4CHM A;  1NU2 A;  5D3X A;  2H7E A;  2DHI A;  2EMT A;  3MPX A;  1MK7 B;  2D9Y A;  4CHJ A;  1Y19 B;  1FB8 A;  1EF1 A;  3D8F A;  1W1H A;  2K00 A;  3SNH A;  2YS3 A;  2UZS A;  1U27 A;  2EC1 A;  1MKE A;  5HE1 A;  2Y8G A;  3NSU A;  2DA0 A;  3QIJ A;  2Y8F A;  1M7E A;  5KQ4 A;  4HAY B;  2UVM A;  3T06 A;  1V61 A;  2GJY A;  5FI1 A;  3AU5 A;  3GYP A;  4EKU A;  2XQN M;  1WJM A;  3O96 A;  2GCJ A;  1QQG A;  4IFS A;  5DHF B;  4A6F B;  2YRY A;  2YF0 A;  4KHB B;  2I1J A;  1LW3 A;  1K5D B;  4HAU B;  1OQN A;  4IOY X;  1I7A A;  1V89 A;  4YON A;  1BWN A;  1X86 A;  3DXE A;  3HQC A;  1MIZ B;  2MKR A;  5C5B B;  3D8E A;  2DTC A;  2W2X D;  2COF A;  1K5G B;  4ZRK A;  4PNK A;  1UPQ A;  2NZ8 B;  1PMS A;  4GXB A;  1GC7 A;  4HHV A;  4HB3 B;  5CLQ B;  1NTY A;  2RSG A;  5D3V A;  4MK0 A;  2J0J A;  3F5R A;  2L1C A;  2I5F A;  4CYE A;  4HAZ B;  2AEH A;  3U8Z A;  3PVU A;  4A6H A;  3M1I B;  4GPT B;  3ULB A;  1RRP B;  1KZG A;  5LOP B;  1H10 A;  1H4R A;  2M38 A;  5DH9 B;  1UNP A;  5D3W A;  2QKL A;  1WI1 A;  5JHG A;  1XR0 B;  4P7I A;  4Z2M B;  4KHO A;  4WJ7 A;  3SUZ A;  1TQZ A;  4HB2 B;  3QBV B;  3ODW A;  4K2P A;  4HAV B;  4ZRI A;  2DX1 A;  1U29 A;  2RNR B;  4EMO A;  2AL6 A;  1X11 A;  2IFS A;  3KRW A;  3TCA A;  4A5K A;  1WGQ A;  1DRO A;  1B55 A;  3P6A A;  2BCJ A;  2VKI A;  2CRF A;  2Z0Q A;  3AJ4 A;  2LOX A;  3X23 A;  4F7H A;  2P8V A;  3SV1 A;  1P3R A;  1W1D A;  2YT0 A;  2J0K A;  2GS0 A;  4F7U P;  4YL8 A;  3ZVR A;  2L2I A;  1PLS A;  1MAI A;  2Z0O A;  5C6R A;  3A8Q A;  3FSS A;  5C79 A;  3PEG A;  3DXC A;  1FHX A;  2IYB A;  1XOD A;  4GMV A;  3U7D A;  5JLJ B;  2FJL A;  2COC A;  2DLW A;  2YS5 A;  1MK9 B;  5HE2 A;  2K2U A;  3PZD A;  3WYF B;  4BBK A;  1WGU A;  3ODO A;  1FAO A;  1U2B A;  1TXD A;  2DHJ A;  4DXA B;  4WSF A;  2J0M A;  1X1F A;  3IVF A;  4NSW A;  1LB1 A;  2DYN A;  1Q67 A;  3TVV A;  2Z0P A;  3PVL A;  4KVG B;  1FHO A;  3MDB C;  5EFX A;  2YS1 A;  2VSZ A;  4IAP A;  1U5F A;  4NY0 A;  1P6S A;  2CY4 A;  1DDW A;  4HDO A;  2DX5 A;  3GYO A;  1MPH A;  3KZ1 A;  3BJI A;  3RCP A;  4WVF B;  3SYX A;  2LUL A;  2EMS A;  3V5W A;  1W1G A;  5L81 A;  5J3Q A;  5DI9 B;  4A6K A;  1RJ2 A;  1OY2 A;  1XD4 A;  2Y7B A;  3VOQ A;  2KGX B;  1U5D A;  3TFM A;  1J0W A;  3TO1 A;  2D9Z A;  3AU4 A;  4A6F A;  2X18 A;  3CXB B;  5J3Y A;  3LJU X;  2H7D A;  3KRX A;  2P0H A;  2JP2 A;  5KCV A;  4PQ0 A;  5CLL B;  4HAW B;  1WJ1 A;  2YT1 A;  4HAX B;  1UPR A;  1EAZ A;  3A98 B;  2V76 A;  1WVH A;  2MFQ A;  1X1G A;  2HTH B;  2DFK A;  2YSZ A;  3PVW A;  1NI2 A;  1PFJ A;  2D10 A;  3D8D A;  2RUK B;  5JHH A;  3KY9 A;  2E2X A;  1ZM0 A;  2RGN B;  3HW2 B;  2R09 A;  3PSC A;  2Q13 A;  4MT7 A;  2ADZ A;  4KHA A;  2COD A;  2DKP A;  3ULC A;  2OTX A;  1N3H A;  2D9W A;  4Y94 A;  5D27 A;  5DHA B;  1FHW A;  4TYZ A;  1AWE A;  1XKE A;  3N7C A;  5FI0 A;  1V88 A;  2UZR A;  2LYD A;  2D2Q A;  3FEH A;  1ZVR A;  2KCJ A;  1FGZ A;  3SO6 A;  4MY6 A;  1X05 A;  1E5W A;  1BAK A;  2OQB A;  1KI1 B;  4HB4 B;  2LOZ A;  2NMB A;  2ROV A;  4K81 A;  1BTN A;  4D0N B;  1J19 A;  5HE0 A;  4GZU A;  2RVB B;  2MWN B;  2DYQ A;  2COA A;  1UEF A;  4K17 A;  3G9W A;  5HE3 A;  4K2O A;  4GN1 A;  1Z87 A;  5C5B A;  2YVC A;  1QC6 A;  1AQC A;  3CIK A;  4L6E A;  3BIN A;  2P0D A;  1GC6 A;  4DX9 0;  1M7R A;  2DKQ A;  2VRW B;  4XWX A;  2R0D A;  4HDQ A;  3QWM A;  1UNQ A;  3F0W A;  1V5M A;  3FM8 C;  2DN6 A;  2N0Y A;  2W2W A;  3ZDT A;  4F7G A;  2N23 A;  1DYN A;  1DDV A;  1TJ6 A;  1UNR A;  2PZ1 A;  1Y5O A;  2CY5 A;  2CAY A;  1NTV A;  3TW1 A;  3P7Z A;  1SHC A;  5D3Y A;  3WA0 A;  1FOE A;  4B6H A;  1I2H A;  3DXD A;  3A8P A;  4EJN A;  2D9X A;  2K2J A;  5JP4 A;  1V5U A;  2M14 A;  2GCL A;  4C0A A;  2ELB A;  2ROZ B;  4ZRJ A;  4Z2N A;  5C16 A;  4DBB A;  3UZT A;  2P0F A;  5J3T A;  1FGY A;  1EVH A;  2KUP A;  5KQ1 A;  5LON B;  4DX8 A;  1U5G A;  1ZC3 B;  2EJ8 A;  1KZ7 A;  4KAX B;  1ISN A;  4HAT B;  1SGH A;  2DHK A;  1ZC4 B;  2J59 M;  1P5T A;  3HK0 A;  5DIF B;  4HB0 B;  2I1K A;  2W2X C;  1GG3 A;  1XCG A;  3OAN A;  3PP2 A;  2ZPY A;  1DDM A;  2ELA A;  2LKO A;  1ZSQ A;  4GMX B;  2MDX A;  1U5E A;  3KSY A;  1MIX A;  4H8S A;  4TKN A;  3ODX A;  3PG7 A;  1OMW A;  5GOW B;  1V5P A;  1EGX A;  1XX0 A;  2D9V A;  3VIA A;  2LG1 A;  2RLO A;  2I5C A;  2D4Q A;  2QKM A;  1BTK A;  2D11 A;  1DBH A;  2HE7 A; 
#chains in the Genus database with same CATH topology
 3ML4 A;  4KHB A;  1WG7 A;  2G35 A;  1IRS A;  4CHM A;  1NU2 A;  5D3X A;  2H7E A;  2DHI A;  2EMT A;  3MPX A;  1MK7 B;  2D9Y A;  4CHJ A;  1Y19 B;  1FB8 A;  1EF1 A;  3D8F A;  1W1H A;  3FVC A;  2K00 A;  5M4Y B;  3SNH A;  2YS3 A;  2UZS A;  1U27 A;  2EC1 A;  1MKE A;  5HE1 A;  3A58 A;  2Y8G A;  3NSU A;  4DIX A;  2DA0 A;  4OSN A;  3QIJ A;  2Y8F A;  1T77 A;  1M7E A;  5KQ4 A;  4HAY B;  2UVM A;  3T06 A;  1V61 A;  2GJY A;  5FI1 A;  2KIE A;  3AU5 A;  3GYP A;  4EKU A;  2XQN M;  1WJM A;  3O96 A;  2GCJ A;  1QQG A;  4QJ3 B;  4IFS A;  5DHF B;  4QXA B;  4A6F B;  2YRY A;  2YF0 A;  4KHB B;  2I1J A;  1LW3 A;  1K5D B;  4HAU B;  2Z13 A;  1OQN A;  4IOY X;  1I7A A;  1V89 A;  4YON A;  1BWN A;  2Z4D A;  3B77 A;  1X86 A;  3DXE A;  3HQC A;  1MIZ B;  2MKR A;  3NWD A;  5C5B B;  3D8E A;  2DTC A;  2W2X D;  2COF A;  2Z59 A;  1K5G B;  4ZRK A;  4PNK A;  1UPQ A;  2NZ8 B;  1PMS A;  4GXB A;  1GC7 A;  4HHV A;  4HB3 B;  5CLQ B;  1NTY A;  2RSG A;  5D3V A;  4MK0 A;  2J0J A;  3F5R A;  2L1C A;  2I5F A;  4CYE A;  4HAZ B;  2AEH A;  3U8Z A;  3PVU A;  2FJU B;  4A6H A;  3M1I B;  4GPT B;  3ULB A;  1RRP B;  1KZG A;  5LOP B;  1H10 A;  1H4R A;  2M38 A;  5IRS A;  5DH9 B;  1UNP A;  5D3W A;  2QKL A;  4D6W A;  1WI1 A;  5JHG A;  1XR0 B;  4P7I A;  4Z2M B;  4KHO A;  4WJ7 A;  3SUZ A;  1TQZ A;  4HB2 B;  3QBV B;  3ODW A;  4K2P A;  4HAV B;  4ZRI A;  2DX1 A;  1U29 A;  2RNR B;  4EMO A;  2AL6 A;  1X11 A;  2IFS A;  3KRW A;  3TCA A;  4A5K A;  1WGQ A;  1DRO A;  1B55 A;  3P6A A;  2BCJ A;  2VKI A;  2CRF A;  2Z0Q A;  3AJ4 A;  2LOX A;  3X23 A;  4F7H A;  2P8V A;  3SV1 A;  1P3R A;  1W1D A;  2YT0 A;  2J0K A;  2GS0 A;  4F7U P;  4YL8 A;  3ZVR A;  2L2I A;  1PLS A;  1MAI A;  2Z0O A;  5C6R A;  5I2S A;  3A8Q A;  3FSS A;  5C79 A;  3PEG A;  3DXC A;  1FHX A;  2IYB A;  1XOD A;  4GMV A;  3U7D A;  5JLJ B;  2FJL A;  2COC A;  2DLW A;  2YS5 A;  1MK9 B;  5HE2 A;  2K2U A;  3PZD A;  3WYF B;  4BBK A;  1WGU A;  3ODO A;  4GOU A;  1FAO A;  1U2B A;  1TXD A;  2DHJ A;  4DXA B;  4WSF A;  2J0M A;  1X1F A;  3IVF A;  4NSW A;  1LB1 A;  2DYN A;  1Q67 A;  3TVV A;  2Z0P A;  3PVL A;  4KVG B;  5LG4 B;  1FHO A;  3MDB C;  5EFX A;  2YS1 A;  2VSZ A;  2Z14 A;  2KUQ A;  4IAP A;  1U5F A;  4NY0 A;  1P6S A;  2CY4 A;  1DDW A;  4HDO A;  2DX5 A;  3GYO A;  1MPH A;  3KZ1 A;  3BJI A;  4L1R A;  3RCP A;  4WVF B;  3SYX A;  2LUL A;  2EMS A;  3V5W A;  1W1G A;  2K8E A;  5L81 A;  5J3Q A;  5DI9 B;  4A6K A;  1RJ2 A;  2YT2 A;  1OY2 A;  1XD4 A;  3DCX A;  2Y7B A;  3VOQ A;  2KGX B;  1U5D A;  3NWA A;  3TFM A;  3U12 A;  1J0W A;  3TO1 A;  2D9Z A;  3AU4 A;  3NWF A;  4A6F A;  2X18 A;  4QJ4 B;  3CXB B;  5J3Y A;  3LJU X;  1ZYI A;  2H7D A;  3KRX A;  2P0H A;  2JP2 A;  5KCV A;  4PQ0 A;  5CLL B;  4HAW B;  1WJ1 A;  2YT1 A;  2NBV A;  4HAX B;  1UPR A;  1EAZ A;  3A98 B;  2V76 A;  1WVH A;  2MFQ A;  1X1G A;  2HTH B;  2DFK A;  2YSZ A;  3PVW A;  1NI2 A;  1PFJ A;  2D10 A;  3D8D A;  2RUK B;  5JHH A;  3KY9 A;  2E2X A;  1ZM0 A;  1MI1 A;  2RGN B;  3HW2 B;  2R09 A;  4HSI A;  3PSC A;  2Q13 A;  4MT7 A;  2ADZ A;  2RRF A;  4KHA A;  2COD A;  2DKP A;  3ULC A;  4QJ5 B;  2OTX A;  1N3H A;  2D9W A;  2GUM A;  4Y94 A;  5D27 A;  2ZKM X;  5DHA B;  1FHW A;  4TYZ A;  1AWE A;  1XKE A;  3N7C A;  5FI0 A;  1V88 A;  2UZR A;  2LYD A;  2D2Q A;  3FEH A;  1ZVR A;  2KCJ A;  1FGZ A;  3SO6 A;  5I2M A;  4MY6 A;  1X05 A;  1E5W A;  1BAK A;  2OQB A;  1KI1 B;  4HB4 B;  2LOZ A;  2NMB A;  2ROV A;  4K81 A;  1BTN A;  4D0N B;  1J19 A;  5HE0 A;  4GZU A;  2RVB B;  2MWN B;  3OHM B;  2DYQ A;  2COA A;  1UEF A;  4K17 A;  3G9W A;  5HE3 A;  4K2O A;  4GN1 A;  1Z87 A;  2KIG A;  5C5B A;  2YVC A;  1QC6 A;  1AQC A;  3CIK A;  4L6E A;  3BIN A;  2P0D A;  1GC6 A;  4DX9 0;  1M7R A;  2DKQ A;  2VRW B;  4XWX A;  2R0D A;  4HDQ A;  3QWM A;  1UNQ A;  3F0W A;  1V5M A;  3FM8 C;  2R2Y A;  2DN6 A;  2N0Y A;  2KR0 A;  2W2W A;  3ZDT A;  4F7G A;  2N23 A;  1DYN A;  1DDV A;  1TJ6 A;  1UNR A;  2PZ1 A;  1Y5O A;  2CY5 A;  2CAY A;  1NTV A;  3TW1 A;  3P7Z A;  4CSQ A;  1SHC A;  5D3Y A;  3WA0 A;  1FOE A;  4B6H A;  1I2H A;  3DXD A;  3A8P A;  4EJN A;  2D9X A;  2K2J A;  5JP4 A;  1V5U A;  2M14 A;  3HIE A;  2GCL A;  4C0A A;  2ELB A;  2ROZ B;  3NW8 A;  4ZRJ A;  4Z2N A;  5C16 A;  4DBB A;  3UZT A;  2P0F A;  5J3T A;  1FGY A;  1EVH A;  2KUP A;  5KQ1 A;  5LON B;  4DX8 A;  1U5G A;  1ZC3 B;  2EJ8 A;  1KZ7 A;  4KAX B;  1ISN A;  4HAT B;  2K49 A;  1SGH A;  2DHK A;  1ZC4 B;  2J59 M;  1P5T A;  3HK0 A;  5DIF B;  4HB0 B;  2I1K A;  2W2X C;  1GG3 A;  1XCG A;  3OAN A;  3PP2 A;  2ZPY A;  1DDM A;  2ELA A;  2LKO A;  1ZSQ A;  4GMX B;  2MDX A;  1U5E A;  3KSY A;  3HSA A;  1MIX A;  4H8S A;  4TKN A;  3ODX A;  3PG7 A;  1OMW A;  5GOW B;  1V5P A;  1EGX A;  1XX0 A;  2D9V A;  4GNK B;  3VIA A;  2LG1 A;  4OT1 A;  2RLO A;  2I5C A;  2D4Q A;  2QKM A;  1BTK A;  2D11 A;  1DBH A;  2HE7 A; 
#chains in the Genus database with same CATH homology
 3ML4 A;  1WG7 A;  2G35 A;  1IRS A;  4CHM A;  1NU2 A;  5D3X A;  2H7E A;  2DHI A;  2EMT A;  3MPX A;  1MK7 B;  2D9Y A;  4CHJ A;  1Y19 B;  1FB8 A;  1EF1 A;  3D8F A;  1W1H A;  2K00 A;  3SNH A;  2YS3 A;  2UZS A;  1U27 A;  2EC1 A;  1MKE A;  5HE1 A;  2Y8G A;  3NSU A;  2DA0 A;  3QIJ A;  2Y8F A;  1M7E A;  5KQ4 A;  4HAY B;  2UVM A;  3T06 A;  1V61 A;  2GJY A;  5FI1 A;  3AU5 A;  3GYP A;  4EKU A;  2XQN M;  1WJM A;  3O96 A;  2GCJ A;  1QQG A;  4IFS A;  5DHF B;  4A6F B;  2YRY A;  2YF0 A;  4KHB B;  2I1J A;  1LW3 A;  1K5D B;  4HAU B;  1OQN A;  4IOY X;  1I7A A;  1V89 A;  4YON A;  1BWN A;  1X86 A;  3DXE A;  3HQC A;  1MIZ B;  2MKR A;  5C5B B;  3D8E A;  2DTC A;  2W2X D;  2COF A;  1K5G B;  4ZRK A;  4PNK A;  1UPQ A;  2NZ8 B;  1PMS A;  4GXB A;  1GC7 A;  4HHV A;  4HB3 B;  5CLQ B;  1NTY A;  2RSG A;  5D3V A;  4MK0 A;  2J0J A;  3F5R A;  2L1C A;  2I5F A;  4CYE A;  4HAZ B;  2AEH A;  3U8Z A;  3PVU A;  4A6H A;  3M1I B;  4GPT B;  3ULB A;  1RRP B;  1KZG A;  5LOP B;  1H10 A;  1H4R A;  2M38 A;  5DH9 B;  1UNP A;  5D3W A;  2QKL A;  1WI1 A;  5JHG A;  1XR0 B;  4P7I A;  4Z2M B;  4KHO A;  4WJ7 A;  3SUZ A;  1TQZ A;  4HB2 B;  3QBV B;  3ODW A;  4K2P A;  4HAV B;  4ZRI A;  2DX1 A;  1U29 A;  2RNR B;  4EMO A;  2AL6 A;  1X11 A;  2IFS A;  3KRW A;  3TCA A;  4A5K A;  1WGQ A;  1DRO A;  1B55 A;  3P6A A;  2BCJ A;  2VKI A;  2CRF A;  2Z0Q A;  3AJ4 A;  2LOX A;  3X23 A;  4F7H A;  2P8V A;  3SV1 A;  1P3R A;  1W1D A;  2YT0 A;  2J0K A;  2GS0 A;  4F7U P;  4YL8 A;  3ZVR A;  2L2I A;  1PLS A;  1MAI A;  2Z0O A;  5C6R A;  3A8Q A;  3FSS A;  5C79 A;  3PEG A;  3DXC A;  1FHX A;  2IYB A;  1XOD A;  4GMV A;  3U7D A;  5JLJ B;  2FJL A;  2COC A;  2DLW A;  2YS5 A;  1MK9 B;  5HE2 A;  2K2U A;  3PZD A;  3WYF B;  4BBK A;  1WGU A;  3ODO A;  1FAO A;  1U2B A;  1TXD A;  2DHJ A;  4DXA B;  4WSF A;  2J0M A;  1X1F A;  3IVF A;  4NSW A;  1LB1 A;  2DYN A;  1Q67 A;  3TVV A;  2Z0P A;  3PVL A;  4KVG B;  1FHO A;  3MDB C;  5EFX A;  2YS1 A;  2VSZ A;  4IAP A;  1U5F A;  4NY0 A;  1P6S A;  2CY4 A;  1DDW A;  4HDO A;  2DX5 A;  3GYO A;  1MPH A;  3KZ1 A;  3BJI A;  3RCP A;  4WVF B;  3SYX A;  2LUL A;  2EMS A;  3V5W A;  1W1G A;  5L81 A;  5J3Q A;  5DI9 B;  4A6K A;  1RJ2 A;  1OY2 A;  1XD4 A;  2Y7B A;  3VOQ A;  2KGX B;  1U5D A;  3TFM A;  1J0W A;  3TO1 A;  2D9Z A;  3AU4 A;  4A6F A;  2X18 A;  3CXB B;  5J3Y A;  3LJU X;  2H7D A;  3KRX A;  2P0H A;  2JP2 A;  5KCV A;  4PQ0 A;  5CLL B;  4HAW B;  1WJ1 A;  2YT1 A;  4HAX B;  1UPR A;  1EAZ A;  3A98 B;  2V76 A;  1WVH A;  2MFQ A;  1X1G A;  2HTH B;  2DFK A;  2YSZ A;  3PVW A;  1NI2 A;  1PFJ A;  2D10 A;  3D8D A;  2RUK B;  5JHH A;  3KY9 A;  2E2X A;  1ZM0 A;  2RGN B;  3HW2 B;  2R09 A;  3PSC A;  2Q13 A;  4MT7 A;  2ADZ A;  4KHA A;  2COD A;  2DKP A;  3ULC A;  2OTX A;  1N3H A;  2D9W A;  4Y94 A;  5D27 A;  5DHA B;  1FHW A;  4TYZ A;  1AWE A;  1XKE A;  3N7C A;  5FI0 A;  1V88 A;  2UZR A;  2LYD A;  2D2Q A;  3FEH A;  1ZVR A;  2KCJ A;  1FGZ A;  3SO6 A;  4MY6 A;  1X05 A;  1E5W A;  1BAK A;  2OQB A;  1KI1 B;  4HB4 B;  2LOZ A;  2NMB A;  2ROV A;  4K81 A;  1BTN A;  4D0N B;  1J19 A;  5HE0 A;  4GZU A;  2RVB B;  2MWN B;  2DYQ A;  2COA A;  1UEF A;  4K17 A;  3G9W A;  5HE3 A;  4K2O A;  4GN1 A;  1Z87 A;  5C5B A;  2YVC A;  1QC6 A;  1AQC A;  3CIK A;  4L6E A;  3BIN A;  2P0D A;  1GC6 A;  4DX9 0;  1M7R A;  2DKQ A;  2VRW B;  4XWX A;  2R0D A;  4HDQ A;  3QWM A;  1UNQ A;  3F0W A;  1V5M A;  3FM8 C;  2DN6 A;  2N0Y A;  2W2W A;  3ZDT A;  4F7G A;  2N23 A;  1DYN A;  1DDV A;  1TJ6 A;  1UNR A;  2PZ1 A;  1Y5O A;  2CY5 A;  2CAY A;  1NTV A;  3TW1 A;  3P7Z A;  1SHC A;  5D3Y A;  3WA0 A;  1FOE A;  4B6H A;  1I2H A;  3DXD A;  3A8P A;  4EJN A;  2D9X A;  2K2J A;  5JP4 A;  1V5U A;  2M14 A;  2GCL A;  4C0A A;  2ELB A;  2ROZ B;  4ZRJ A;  4Z2N A;  5C16 A;  4DBB A;  3UZT A;  2P0F A;  5J3T A;  1FGY A;  1EVH A;  2KUP A;  5KQ1 A;  5LON B;  4DX8 A;  1U5G A;  1ZC3 B;  2EJ8 A;  1KZ7 A;  4KAX B;  1ISN A;  4HAT B;  1SGH A;  2DHK A;  1ZC4 B;  2J59 M;  1P5T A;  3HK0 A;  5DIF B;  4HB0 B;  2I1K A;  2W2X C;  1GG3 A;  1XCG A;  3OAN A;  3PP2 A;  2ZPY A;  1DDM A;  2ELA A;  2LKO A;  1ZSQ A;  4GMX B;  2MDX A;  1U5E A;  3KSY A;  1MIX A;  4H8S A;  4TKN A;  3ODX A;  3PG7 A;  1OMW A;  5GOW B;  1V5P A;  1EGX A;  1XX0 A;  2D9V A;  3VIA A;  2LG1 A;  2RLO A;  2I5C A;  2D4Q A;  2QKM A;  1BTK A;  2D11 A;  1DBH A;  2HE7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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