4K2PA

The structure of a quintuple mutant of the tiam1 ph-cc-ex domain
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
238
structure length
238
Chain Sequence
TVRKAGALAVKNFLVHKKNKKVESATRRKWKHYWVSLKGCTLFFYESDGRSGIDHNSIPKHAVWVENSIVQAVPEHPKKDFVFCLSNSLGDAFLFQTTSQTELENWITAIHSACATAVARHHHKEDTLRLLKSEIKKLEQKIDMDEKLKKMGELQLSSVTDSKAAATILDQIFVWEQNLEQFQMDLFRFRCYLASLQGGELPNPKRLLAFASRPTKVAMGRLGIFSVSSFHALVAART
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title High-resolution structure of the Tiam1 PHn-CC-Ex domain.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords T-lymphoma invasion and metastasis-inducing protein 1
total genus 78
structure length 238
sequence length 238
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-04-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF18385 Tiam_CC_Ex T-lymphoma invasion and metastasis CC-Ex domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 4k2pA01
1M7EA 1X11A 2G35A 4HATB 4HAYB 4HAXB 2LKOA 2YS1A 2D10A 4NSWA 1V88A 1WJ1A 1TXDA 2DFKA 1NTYA 3KRWA 5GOWB 5LONB 2D2QA 3KZ1A 3MDBC 2ELBA 2GCJA 2ELAA 2J0JA 5C5BA 3ODWA 4K2OA 1K5GB 1PMSA 2D4QA 3PZDA 1Q67A 3BJIA 2I5FA 4F7GA 2P0HA 1TJ6A 4Z2MB 3WYFB 1RJ2A 1UNQA 4GN1A 4A6HA 4P7IA 2GJYA 4F7HA 1IRSA 4YONA 2LOZA 2Z0OA 3RCPA 1OQNA 2KUPA 2D9ZA 3D8EA 2QKMA 3P7ZA 1J19A 1Z87A 2AL6A 3BINA 4K17A 2LULA 2V76A 2I1KA 2DN6A 1U5DA 4DBBA 1NI2A 1SHCA 1U2BA 2RNRB 3IVFA 2DTCA 3P6AA 1DDVA 2CAYA 1FOEA 3PVUA 3WA0A 1U27A 2VRWB 3PVWA 2DA0A 3TFMA 3G9WA 4KAXB 2DKPA 4HHVA 2EMTA 2K2JA 3A8PA 2DYNA 2Y7BA 3D8FA 5CLLB 1N3HA 2HE7A 4HAZB 2N23A 1DYNA 2COCA 1I7AA 4IOYX 1W1HA 4YL8A 1U5EA 3F0WA 1E5WA 1WJMA 1WVHA 2DX1A 2VSZA 1XD4A 1ZM0A 3NSUA 1XODA 5DHFB 3QIJA 2COFA 3PVLA 3PP2A 5HE1A 5J3TA 5FI0A 5HE0A 3F5RA 2GS0A 1K5DB 3KY9A 2CODA 2P0DA 5KCVA 2H7DA 2JP2A 2D9XA 4F7UP 3ZDTA 2Z0PA 2PZ1A 4XWXA 4HAWB 4Y94A 1QQGA 1FGZA 1FHXA 3FM8C 3DXDA 4HB3B 2ZPYA 3ODXA 5JP4A 3KRXA 4TYZA 1XX0A 2ROZB 3DXEA 2IFSA 1BWNA 2J59M 1W1GA 2W2WA 4PQ0A 1WG7A 1DDMA 2NMBA 1KZGA 2DHIA 1RRPB 5DHAB 4Z2NA 4HAUB 1B55A 2NZ8B 3TVVA 1LW3A 5HE2A 2MWNB 5DIFB 4HB4B 1PLSA 3QBVB 4EJNA 1OY2A 5D3XA 1U29A 4KHAA 4MT7A 1UEFA 1BTNA 2OQBA 4HB0B 2D9VA 2DHJA 3PG7A 4D0NB 4MK0A 5DH9B 4HDQA 1EGXA 2D9WA 4WVFB 5DI9B 1DBHA 4KHOA 5J3YA 3ULCA 1UPRA 1NTVA 5KQ1A 3AJ4A 4H8SA 4ZRIA 3SUZA 3AU4A 3D8DA 1P3RA 2EMSA 2KGXB 1X1GA 3HQCA 1TQZA 2RUKB 1EF1A 2Q13A 2UZSA 3ZVRA 2I1JA 2COAA 2OTXA 2MKRA 2YT0A 1I2HA 2HTHB 4MY6A 1ZVRA 1UNRA 3SNHA 4A5KA 1X1FA 2LYDA 1MKEA 2J0KA 3PSCA 5JHGA 1WGUA 4A6FB 1H4RA 1X05A 5D3WA 2VKIA 2ROVA 3UZTA 3LJUX 2M14A 1XCGA 4GPTB 1GC7A 2D9YA 3U7DA 3T06A 3O96A 1FAOA 2YS3A 1FB8A 4K2PA 2LOXA 2EJ8A 1XR0B 3DXCA 4BBKA 1H10A 4CHJA 5JLJB 2BCJA 1P6SA 2EC1A 2P0FA 3CIKA 1X86A 2RLOA 1W1DA 2YF0A 2DYQA 3KSYA 2P8VA 1BAKA 1MIZB 2GCLA 5D3YA 2CRFA 2W2XD 3HW2B 2Y8GA 3HK0A 5HE3A 4CYEA 2RSGA 1MPHA 3QWMA 2RVBB 1FHOA 3AU5A 2XQNM 1LB1A 3A8QA 2L1CA 4WJ7A 2CY4A 1MK9B 4ZRKA 3U8ZA 3GYOA 2DLWA 5D27A 4DX8A 3TW1A 3ODOA 2LG1A 1UPQA 1M7RA 4TKNA 4EMOA 1EAZA 4HAVB 2Z0QA 1KZ7A 4EKUA 5C5BB 2KCJA 3GYPA 4K81A 2H7EA 1J0WA 5D3VA 1XKEA 1GC6A 5J3QA 2N0YA 1SGHA 3V5WA 2R0DA 2M38A 1Y19B 3CXBB 1MAIA 3ULBA 3TO1A 1MIXA 2YSZA 4DXAB 5JHHA 2R09A 1WGQA 4GZUA 1UNPA 5KQ4A 2I5CA 2QKLA 3TCAA 1PFJA 2DHKA 4CHMA 1NU2A 4HDOA 1V5PA 3SYXA 1V5UA 2FJLA 4IFSA 4B6HA 1AQCA 1U5FA 4KHBB 1DROA 3A98B 2YS5A 4A6KA 1KI1B 1U5GA 1BTKA 1ZC3B 5FI1A 1WI1A 4C0AA 2YVCA 4WSFA 1FHWA 1AWEA 4IAPA 2W2XC 4A6FA 1OMWA 3VIAA 3N7CA 3PEGA 5C6RA 5L81A 1P5TA 3FEHA 3X23A 2E2XA 5CLQB 3M1IB 2CY5A 1MK7B 1V89A 5C79A 3FSSA 3SV1A 4L6EA 2AEHA 2YRYA 4NY0A 1ZSQA 3MPXA 5LOPB 2K00A 2UZRA 1FGYA 2D11A 3OANA 3VOQA 1V61A 2DKQA 4DX90 1Y5OA 2X18A 4GMVA 1EVHA 3ML4A 4PNKA 2IYBA 1ZC4B 2MDXA 2YT1A 2RGNB 2L2IA 2DX5A 2ADZA 3SO6A 4GXBA 5EFXA 2MFQA 4ZRJA 4GMXB 4HB2B 2Y8FA 4KVGB 5C16A 2J0MA 1QC6A 1ISNA 2K2UA 2UVMA 1V5MA 1GG3A 1DDWA
chains in the Genus database with same CATH superfamily
1M7EA 1ZYIA 1X11A 2G35A 4HATB 4HAYB 4HAXB 2LKOA 2YS1A 2D10A 4NSWA 1V88A 1WJ1A 1TXDA 2DFKA 1NTYA 3KRWA 5GOWB 5LONB 2D2QA 3KZ1A 3MDBC 2ELBA 2GCJA 2ELAA 2J0JA 5C5BA 3ODWA 4K2OA 1K5GB 1PMSA 2D4QA 3PZDA 1Q67A 3BJIA 2I5FA 4F7GA 2P0HA 1TJ6A 4Z2MB 3WYFB 1RJ2A 1UNQA 4GN1A 4GOUA 4A6HA 3OHMB 2GJYA 4P7IA 4F7HA 1IRSA 4YONA 2LOZA 2Z0OA 3RCPA 1OQNA 2KUPA 2D9ZA 3D8EA 2QKMA 3P7ZA 1J19A 1Z87A 2AL6A 3BINA 4K17A 4QJ4B 2LULA 2V76A 2I1KA 2DN6A 1U5DA 4DBBA 1NI2A 1SHCA 1U2BA 2RNRB 3IVFA 2DTCA 3P6AA 1DDVA 2CAYA 1FOEA 3PVUA 4KHBA 3WA0A 4HSIA 1U27A 2VRWB 3PVWA 3NWDA 2DA0A 4DIXA 3TFMA 3G9WA 4KAXB 2DKPA 2GUMA 4HHVA 2EMTA 2K2JA 3A8PA 2NBVA 2DYNA 2Y7BA 4GNKB 3D8FA 5CLLB 1N3HA 2HE7A 5I2SA 4HAZB 2N23A 1DYNA 2COCA 1I7AA 4IOYX 1W1HA 4YL8A 1U5EA 3F0WA 1E5WA 2KUQA 1WJMA 1WVHA 2DX1A 2VSZA 4QJ5B 1XD4A 1ZM0A 1XODA 3NSUA 5DHFB 3QIJA 2FJUB 2COFA 3HSAA 3PP2A 3PVLA 5HE1A 5J3TA 5FI0A 5HE0A 3F5RA 2GS0A 1K5DB 3KY9A 2CODA 2P0DA 5KCVA 2H7DA 2JP2A 2D9XA 4F7UP 3ZDTA 2Z0PA 2PZ1A 4XWXA 4HAWB 4Y94A 1QQGA 1FGZA 1FHXA 3FM8C 2Z4DA 3DXDA 3NWAA 4HB3B 2ZPYA 3ODXA 5JP4A 3KRXA 4TYZA 1XX0A 2ROZB 3DXEA 2IFSA 3U12A 1BWNA 2J59M 1W1GA 2W2WA 4PQ0A 1WG7A 1DDMA 2NMBA 1KZGA 2DHIA 1RRPB 5DHAB 4Z2NA 4HAUB 1B55A 2NZ8B 3TVVA 1LW3A 5HE2A 2MWNB 5DIFB 2KIEA 4QXAB 4HB4B 1PLSA 3QBVB 4EJNA 1OY2A 5D3XA 1T77A 1U29A 4KHAA 4MT7A 1UEFA 1BTNA 2OQBA 4HB0B 2D9VA 2DHJA 3NWFA 3PG7A 4D0NB 4MK0A 5DH9B 4HDQA 1EGXA 4QJ3B 2D9WA 4WVFB 5DI9B 1DBHA 4KHOA 5J3YA 3ULCA 2Z14A 1UPRA 1NTVA 5KQ1A 3AJ4A 4L1RA 4H8SA 4ZRIA 3SUZA 3AU4A 3D8DA 1P3RA 2EMSA 2KGXB 1X1GA 3HQCA 1TQZA 2RUKB 1EF1A 2Q13A 2UZSA 3ZVRA 2I1JA 2COAA 2OTXA 2MKRA 2YT0A 1I2HA 4D6WA 2HTHB 4MY6A 1ZVRA 4OT1A 1UNRA 3SNHA 4A5KA 3DCXA 1X1FA 2LYDA 2K49A 1MKEA 2J0KA 3PSCA 5JHGA 1WGUA 4A6FB 1H4RA 1X05A 5D3WA 2VKIA 2ROVA 3UZTA 3LJUX 2M14A 1XCGA 4GPTB 1GC7A 2D9YA 3U7DA 3T06A 3O96A 1FAOA 2YS3A 1FB8A 4K2PA 2LOXA 2EJ8A 1XR0B 2RRFA 3DXCA 4BBKA 3A58A 1H10A 4CHJA 5JLJB 2BCJA 1P6SA 2EC1A 2P0FA 3CIKA 4OSNA 1X86A 2RLOA 1W1DA 2YF0A 2DYQA 3KSYA 2P8VA 1BAKA 1MIZB 2GCLA 5D3YA 2CRFA 2W2XD 3HW2B 2Y8GA 3HK0A 5HE3A 4CYEA 2RSGA 1MPHA 3QWMA 2RVBB 1FHOA 3AU5A 2XQNM 1LB1A 3A8QA 2L1CA 4WJ7A 2CY4A 1MK9B 4ZRKA 3U8ZA 2KR0A 3GYOA 2DLWA 5D27A 4DX8A 3TW1A 3ODOA 2LG1A 1UPQA 1M7RA 4TKNA 4EMOA 1EAZA 4HAVB 3FVCA 2Z0QA 1KZ7A 4EKUA 5C5BB 2KCJA 3GYPA 4K81A 2H7EA 2K8EA 1J0WA 5D3VA 1XKEA 1GC6A 5J3QA 2N0YA 1SGHA 3V5WA 5IRSA 2R0DA 2M38A 1Y19B 3CXBB 1MAIA 3ULBA 3TO1A 1MIXA 2YSZA 4DXAB 2KIGA 5JHHA 2R09A 1WGQA 4GZUA 1UNPA 5KQ4A 2I5CA 2QKLA 3TCAA 1PFJA 2DHKA 4CHMA 1NU2A 4HDOA 1V5PA 3SYXA 1V5UA 2FJLA 4IFSA 4B6HA 2R2YA 1AQCA 1U5FA 4KHBB 1DROA 3A98B 2YS5A 4A6KA 1KI1B 1U5GA 2ZKMX 1BTKA 1ZC3B 5FI1A 5M4YB 1WI1A 4C0AA 1MI1A 2YVCA 3HIEA 2Z59A 4WSFA 1FHWA 1AWEA 4IAPA 2W2XC 4A6FA 1OMWA 3VIAA 3N7CA 3PEGA 5C6RA 5L81A 1P5TA 3FEHA 3X23A 2E2XA 5CLQB 3M1IB 2CY5A 2YT2A 1MK7B 1V89A 5C79A 4CSQA 3FSSA 3SV1A 4L6EA 2AEHA 2YRYA 4NY0A 1ZSQA 3MPXA 5LOPB 2K00A 5LG4B 2UZRA 1FGYA 2D11A 3OANA 3VOQA 1V61A 2DKQA 4DX90 1Y5OA 2X18A 4GMVA 1EVHA 3ML4A 3B77A 4PNKA 2IYBA 1ZC4B 2MDXA 2YT1A 2RGNB 2L2IA 2DX5A 2ADZA 3SO6A 4GXBA 5EFXA 3NW8A 5I2MA 2MFQA 4ZRJA 4GMXB 4HB2B 2Z13A 2Y8FA 4KVGB 5C16A 2J0MA 1QC6A 1ISNA 2K2UA 2UVMA 1V5MA 1GG3A 1DDWA
chains in the Genus database with same CATH topology
1M7EA 1X11A 2G35A 4HATB 4HAYB 4HAXB 2LKOA 2YS1A 2D10A 4NSWA 1V88A 1WJ1A 1TXDA 2DFKA 1NTYA 3KRWA 5GOWB 5LONB 2D2QA 3KZ1A 3MDBC 2ELBA 2GCJA 2ELAA 2J0JA 5C5BA 3ODWA 4K2OA 1K5GB 1PMSA 2D4QA 3PZDA 1Q67A 3BJIA 2I5FA 4F7GA 2P0HA 1TJ6A 4Z2MB 3WYFB 1RJ2A 1UNQA 4GN1A 4A6HA 4P7IA 2GJYA 4F7HA 1IRSA 4YONA 2LOZA 2Z0OA 3RCPA 1OQNA 2KUPA 2D9ZA 3D8EA 2QKMA 3P7ZA 1J19A 1Z87A 2AL6A 3BINA 4K17A 2LULA 2V76A 2I1KA 2DN6A 1U5DA 4DBBA 1NI2A 1SHCA 1U2BA 2RNRB 3IVFA 2DTCA 3P6AA 1DDVA 2CAYA 1FOEA 3PVUA 3WA0A 1U27A 2VRWB 3PVWA 2DA0A 3TFMA 3G9WA 4KAXB 2DKPA 4HHVA 2EMTA 2K2JA 3A8PA 2DYNA 2Y7BA 3D8FA 5CLLB 1N3HA 2HE7A 4HAZB 2N23A 1DYNA 2COCA 1I7AA 4IOYX 1W1HA 4YL8A 1U5EA 3F0WA 1E5WA 1WJMA 1WVHA 2DX1A 2VSZA 1XD4A 1ZM0A 3NSUA 1XODA 5DHFB 3QIJA 2COFA 3PVLA 3PP2A 5HE1A 5J3TA 5FI0A 5HE0A 3F5RA 2GS0A 1K5DB 3KY9A 2CODA 2P0DA 5KCVA 2H7DA 2JP2A 2D9XA 4F7UP 3ZDTA 2Z0PA 2PZ1A 4XWXA 4HAWB 4Y94A 1QQGA 1FGZA 1FHXA 3FM8C 3DXDA 4HB3B 2ZPYA 3ODXA 5JP4A 3KRXA 4TYZA 1XX0A 2ROZB 3DXEA 2IFSA 1BWNA 2J59M 1W1GA 2W2WA 4PQ0A 1WG7A 1DDMA 2NMBA 1KZGA 2DHIA 1RRPB 5DHAB 4Z2NA 4HAUB 1B55A 2NZ8B 3TVVA 1LW3A 5HE2A 2MWNB 5DIFB 4HB4B 1PLSA 3QBVB 4EJNA 1OY2A 5D3XA 1U29A 4KHAA 4MT7A 1UEFA 1BTNA 2OQBA 4HB0B 2D9VA 2DHJA 3PG7A 4D0NB 4MK0A 5DH9B 4HDQA 1EGXA 2D9WA 4WVFB 5DI9B 1DBHA 4KHOA 5J3YA 3ULCA 1UPRA 1NTVA 5KQ1A 3AJ4A 4H8SA 4ZRIA 3SUZA 3AU4A 3D8DA 1P3RA 2EMSA 2KGXB 1X1GA 3HQCA 1TQZA 2RUKB 1EF1A 2Q13A 2UZSA 3ZVRA 2I1JA 2COAA 2OTXA 2MKRA 2YT0A 1I2HA 2HTHB 4MY6A 1ZVRA 1UNRA 3SNHA 4A5KA 1X1FA 2LYDA 1MKEA 2J0KA 3PSCA 5JHGA 1WGUA 4A6FB 1H4RA 1X05A 5D3WA 2VKIA 2ROVA 3UZTA 3LJUX 2M14A 1XCGA 4GPTB 1GC7A 2D9YA 3U7DA 3T06A 3O96A 1FAOA 2YS3A 1FB8A 4K2PA 2LOXA 2EJ8A 1XR0B 3DXCA 4BBKA 1H10A 4CHJA 5JLJB 2BCJA 1P6SA 2EC1A 2P0FA 3CIKA 1X86A 2RLOA 1W1DA 2YF0A 2DYQA 3KSYA 2P8VA 1BAKA 1MIZB 2GCLA 5D3YA 2CRFA 2W2XD 3HW2B 2Y8GA 3HK0A 5HE3A 4CYEA 2RSGA 1MPHA 3QWMA 2RVBB 1FHOA 3AU5A 2XQNM 1LB1A 3A8QA 2L1CA 4WJ7A 2CY4A 1MK9B 4ZRKA 3U8ZA 3GYOA 2DLWA 5D27A 4DX8A 3TW1A 3ODOA 2LG1A 1UPQA 1M7RA 4TKNA 4EMOA 1EAZA 4HAVB 2Z0QA 1KZ7A 4EKUA 5C5BB 2KCJA 3GYPA 4K81A 2H7EA 1J0WA 5D3VA 1XKEA 1GC6A 5J3QA 2N0YA 1SGHA 3V5WA 2R0DA 2M38A 1Y19B 3CXBB 1MAIA 3ULBA 3TO1A 1MIXA 2YSZA 4DXAB 5JHHA 2R09A 1WGQA 4GZUA 1UNPA 5KQ4A 2I5CA 2QKLA 3TCAA 1PFJA 2DHKA 4CHMA 1NU2A 4HDOA 1V5PA 3SYXA 1V5UA 2FJLA 4IFSA 4B6HA 1AQCA 1U5FA 4KHBB 1DROA 3A98B 2YS5A 4A6KA 1KI1B 1U5GA 1BTKA 1ZC3B 5FI1A 1WI1A 4C0AA 2YVCA 4WSFA 1FHWA 1AWEA 4IAPA 2W2XC 4A6FA 1OMWA 3VIAA 3N7CA 3PEGA 5C6RA 5L81A 1P5TA 3FEHA 3X23A 2E2XA 5CLQB 3M1IB 2CY5A 1MK7B 1V89A 5C79A 3FSSA 3SV1A 4L6EA 2AEHA 2YRYA 4NY0A 1ZSQA 3MPXA 5LOPB 2K00A 2UZRA 1FGYA 2D11A 3OANA 3VOQA 1V61A 2DKQA 4DX90 1Y5OA 2X18A 4GMVA 1EVHA 3ML4A 4PNKA 2IYBA 1ZC4B 2MDXA 2YT1A 2RGNB 2L2IA 2DX5A 2ADZA 3SO6A 4GXBA 5EFXA 2MFQA 4ZRJA 4GMXB 4HB2B 2Y8FA 4KVGB 5C16A 2J0MA 1QC6A 1ISNA 2K2UA 2UVMA 1V5MA 1GG3A 1DDWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M7E A;  1X11 A;  2G35 A;  4HAT B;  4HAY B;  4HAX B;  2LKO A;  2YS1 A;  2D10 A;  4NSW A;  1V88 A;  1WJ1 A;  1TXD A;  2DFK A;  1NTY A;  3KRW A;  5GOW B;  5LON B;  2D2Q A;  3KZ1 A;  3MDB C;  2ELB A;  2GCJ A;  2ELA A;  2J0J A;  5C5B A;  3ODW A;  4K2O A;  1K5G B;  1PMS A;  2D4Q A;  3PZD A;  1Q67 A;  3BJI A;  2I5F A;  4F7G A;  2P0H A;  1TJ6 A;  4Z2M B;  3WYF B;  1RJ2 A;  1UNQ A;  4GN1 A;  4A6H A;  4P7I A;  2GJY A;  4F7H A;  1IRS A;  4YON A;  2LOZ A;  2Z0O A;  3RCP A;  1OQN A;  2KUP A;  2D9Z A;  3D8E A;  2QKM A;  3P7Z A;  1J19 A;  1Z87 A;  2AL6 A;  3BIN A;  4K17 A;  2LUL A;  2V76 A;  2I1K A;  2DN6 A;  1U5D A;  4DBB A;  1NI2 A;  1SHC A;  1U2B A;  2RNR B;  3IVF A;  2DTC A;  3P6A A;  1DDV A;  2CAY A;  1FOE A;  3PVU A;  3WA0 A;  1U27 A;  2VRW B;  3PVW A;  2DA0 A;  3TFM A;  3G9W A;  4KAX B;  2DKP A;  4HHV A;  2EMT A;  2K2J A;  3A8P A;  2DYN A;  2Y7B A;  3D8F A;  5CLL B;  1N3H A;  2HE7 A;  4HAZ B;  2N23 A;  1DYN A;  2COC A;  1I7A A;  4IOY X;  1W1H A;  4YL8 A;  1U5E A;  3F0W A;  1E5W A;  1WJM A;  1WVH A;  2DX1 A;  2VSZ A;  1XD4 A;  1ZM0 A;  3NSU A;  1XOD A;  5DHF B;  3QIJ A;  2COF A;  3PVL A;  3PP2 A;  5HE1 A;  5J3T A;  5FI0 A;  5HE0 A;  3F5R A;  2GS0 A;  1K5D B;  3KY9 A;  2COD A;  2P0D A;  5KCV A;  2H7D A;  2JP2 A;  2D9X A;  4F7U P;  3ZDT A;  2Z0P A;  2PZ1 A;  4XWX A;  4HAW B;  4Y94 A;  1QQG A;  1FGZ A;  1FHX A;  3FM8 C;  3DXD A;  4HB3 B;  2ZPY A;  3ODX A;  5JP4 A;  3KRX A;  4TYZ A;  1XX0 A;  2ROZ B;  3DXE A;  2IFS A;  1BWN A;  2J59 M;  1W1G A;  2W2W A;  4PQ0 A;  1WG7 A;  1DDM A;  2NMB A;  1KZG A;  2DHI A;  1RRP B;  5DHA B;  4Z2N A;  4HAU B;  1B55 A;  2NZ8 B;  3TVV A;  1LW3 A;  5HE2 A;  2MWN B;  5DIF B;  4HB4 B;  1PLS A;  3QBV B;  4EJN A;  1OY2 A;  5D3X A;  1U29 A;  4KHA A;  4MT7 A;  1UEF A;  1BTN A;  2OQB A;  4HB0 B;  2D9V A;  2DHJ A;  3PG7 A;  4D0N B;  4MK0 A;  5DH9 B;  4HDQ A;  1EGX A;  2D9W A;  4WVF B;  5DI9 B;  1DBH A;  4KHO A;  5J3Y A;  3ULC A;  1UPR A;  1NTV A;  5KQ1 A;  3AJ4 A;  4H8S A;  4ZRI A;  3SUZ A;  3AU4 A;  3D8D A;  1P3R A;  2EMS A;  2KGX B;  1X1G A;  3HQC A;  1TQZ A;  2RUK B;  1EF1 A;  2Q13 A;  2UZS A;  3ZVR A;  2I1J A;  2COA A;  2OTX A;  2MKR A;  2YT0 A;  1I2H A;  2HTH B;  4MY6 A;  1ZVR A;  1UNR A;  3SNH A;  4A5K A;  1X1F A;  2LYD A;  1MKE A;  2J0K A;  3PSC A;  5JHG A;  1WGU A;  4A6F B;  1H4R A;  1X05 A;  5D3W A;  2VKI A;  2ROV A;  3UZT A;  3LJU X;  2M14 A;  1XCG A;  4GPT B;  1GC7 A;  2D9Y A;  3U7D A;  3T06 A;  3O96 A;  1FAO A;  2YS3 A;  1FB8 A;  4K2P A;  2LOX A;  2EJ8 A;  1XR0 B;  3DXC A;  4BBK A;  1H10 A;  4CHJ A;  5JLJ B;  2BCJ A;  1P6S A;  2EC1 A;  2P0F A;  3CIK A;  1X86 A;  2RLO A;  1W1D A;  2YF0 A;  2DYQ A;  3KSY A;  2P8V A;  1BAK A;  1MIZ B;  2GCL A;  5D3Y A;  2CRF A;  2W2X D;  3HW2 B;  2Y8G A;  3HK0 A;  5HE3 A;  4CYE A;  2RSG A;  1MPH A;  3QWM A;  2RVB B;  1FHO A;  3AU5 A;  2XQN M;  1LB1 A;  3A8Q A;  2L1C A;  4WJ7 A;  2CY4 A;  1MK9 B;  4ZRK A;  3U8Z A;  3GYO A;  2DLW A;  5D27 A;  4DX8 A;  3TW1 A;  3ODO A;  2LG1 A;  1UPQ A;  1M7R A;  4TKN A;  4EMO A;  1EAZ A;  4HAV B;  2Z0Q A;  1KZ7 A;  4EKU A;  5C5B B;  2KCJ A;  3GYP A;  4K81 A;  2H7E A;  1J0W A;  5D3V A;  1XKE A;  1GC6 A;  5J3Q A;  2N0Y A;  1SGH A;  3V5W A;  2R0D A;  2M38 A;  1Y19 B;  3CXB B;  1MAI A;  3ULB A;  3TO1 A;  1MIX A;  2YSZ A;  4DXA B;  5JHH A;  2R09 A;  1WGQ A;  4GZU A;  1UNP A;  5KQ4 A;  2I5C A;  2QKL A;  3TCA A;  1PFJ A;  2DHK A;  4CHM A;  1NU2 A;  4HDO A;  1V5P A;  3SYX A;  1V5U A;  2FJL A;  4IFS A;  4B6H A;  1AQC A;  1U5F A;  4KHB B;  1DRO A;  3A98 B;  2YS5 A;  4A6K A;  1KI1 B;  1U5G A;  1BTK A;  1ZC3 B;  5FI1 A;  1WI1 A;  4C0A A;  2YVC A;  4WSF A;  1FHW A;  1AWE A;  4IAP A;  2W2X C;  4A6F A;  1OMW A;  3VIA A;  3N7C A;  3PEG A;  5C6R A;  5L81 A;  1P5T A;  3FEH A;  3X23 A;  2E2X A;  5CLQ B;  3M1I B;  2CY5 A;  1MK7 B;  1V89 A;  5C79 A;  3FSS A;  3SV1 A;  4L6E A;  2AEH A;  2YRY A;  4NY0 A;  1ZSQ A;  3MPX A;  5LOP B;  2K00 A;  2UZR A;  1FGY A;  2D11 A;  3OAN A;  3VOQ A;  1V61 A;  2DKQ A;  4DX9 0;  1Y5O A;  2X18 A;  4GMV A;  1EVH A;  3ML4 A;  4PNK A;  2IYB A;  1ZC4 B;  2MDX A;  2YT1 A;  2RGN B;  2L2I A;  2DX5 A;  2ADZ A;  3SO6 A;  4GXB A;  5EFX A;  2MFQ A;  4ZRJ A;  4GMX B;  4HB2 B;  2Y8F A;  4KVG B;  5C16 A;  2J0M A;  1QC6 A;  1ISN A;  2K2U A;  2UVM A;  1V5M A;  1GG3 A;  1DDW A; 
#chains in the Genus database with same CATH topology
 1M7E A;  1ZYI A;  1X11 A;  2G35 A;  4HAT B;  4HAY B;  4HAX B;  2LKO A;  2YS1 A;  2D10 A;  4NSW A;  1V88 A;  1WJ1 A;  1TXD A;  2DFK A;  1NTY A;  3KRW A;  5GOW B;  5LON B;  2D2Q A;  3KZ1 A;  3MDB C;  2ELB A;  2GCJ A;  2ELA A;  2J0J A;  5C5B A;  3ODW A;  4K2O A;  1K5G B;  1PMS A;  2D4Q A;  3PZD A;  1Q67 A;  3BJI A;  2I5F A;  4F7G A;  2P0H A;  1TJ6 A;  4Z2M B;  3WYF B;  1RJ2 A;  1UNQ A;  4GN1 A;  4GOU A;  4A6H A;  3OHM B;  2GJY A;  4P7I A;  4F7H A;  1IRS A;  4YON A;  2LOZ A;  2Z0O A;  3RCP A;  1OQN A;  2KUP A;  2D9Z A;  3D8E A;  2QKM A;  3P7Z A;  1J19 A;  1Z87 A;  2AL6 A;  3BIN A;  4K17 A;  4QJ4 B;  2LUL A;  2V76 A;  2I1K A;  2DN6 A;  1U5D A;  4DBB A;  1NI2 A;  1SHC A;  1U2B A;  2RNR B;  3IVF A;  2DTC A;  3P6A A;  1DDV A;  2CAY A;  1FOE A;  3PVU A;  4KHB A;  3WA0 A;  4HSI A;  1U27 A;  2VRW B;  3PVW A;  3NWD A;  2DA0 A;  4DIX A;  3TFM A;  3G9W A;  4KAX B;  2DKP A;  2GUM A;  4HHV A;  2EMT A;  2K2J A;  3A8P A;  2NBV A;  2DYN A;  2Y7B A;  4GNK B;  3D8F A;  5CLL B;  1N3H A;  2HE7 A;  5I2S A;  4HAZ B;  2N23 A;  1DYN A;  2COC A;  1I7A A;  4IOY X;  1W1H A;  4YL8 A;  1U5E A;  3F0W A;  1E5W A;  2KUQ A;  1WJM A;  1WVH A;  2DX1 A;  2VSZ A;  4QJ5 B;  1XD4 A;  1ZM0 A;  1XOD A;  3NSU A;  5DHF B;  3QIJ A;  2FJU B;  2COF A;  3HSA A;  3PP2 A;  3PVL A;  5HE1 A;  5J3T A;  5FI0 A;  5HE0 A;  3F5R A;  2GS0 A;  1K5D B;  3KY9 A;  2COD A;  2P0D A;  5KCV A;  2H7D A;  2JP2 A;  2D9X A;  4F7U P;  3ZDT A;  2Z0P A;  2PZ1 A;  4XWX A;  4HAW B;  4Y94 A;  1QQG A;  1FGZ A;  1FHX A;  3FM8 C;  2Z4D A;  3DXD A;  3NWA A;  4HB3 B;  2ZPY A;  3ODX A;  5JP4 A;  3KRX A;  4TYZ A;  1XX0 A;  2ROZ B;  3DXE A;  2IFS A;  3U12 A;  1BWN A;  2J59 M;  1W1G A;  2W2W A;  4PQ0 A;  1WG7 A;  1DDM A;  2NMB A;  1KZG A;  2DHI A;  1RRP B;  5DHA B;  4Z2N A;  4HAU B;  1B55 A;  2NZ8 B;  3TVV A;  1LW3 A;  5HE2 A;  2MWN B;  5DIF B;  2KIE A;  4QXA B;  4HB4 B;  1PLS A;  3QBV B;  4EJN A;  1OY2 A;  5D3X A;  1T77 A;  1U29 A;  4KHA A;  4MT7 A;  1UEF A;  1BTN A;  2OQB A;  4HB0 B;  2D9V A;  2DHJ A;  3NWF A;  3PG7 A;  4D0N B;  4MK0 A;  5DH9 B;  4HDQ A;  1EGX A;  4QJ3 B;  2D9W A;  4WVF B;  5DI9 B;  1DBH A;  4KHO A;  5J3Y A;  3ULC A;  2Z14 A;  1UPR A;  1NTV A;  5KQ1 A;  3AJ4 A;  4L1R A;  4H8S A;  4ZRI A;  3SUZ A;  3AU4 A;  3D8D A;  1P3R A;  2EMS A;  2KGX B;  1X1G A;  3HQC A;  1TQZ A;  2RUK B;  1EF1 A;  2Q13 A;  2UZS A;  3ZVR A;  2I1J A;  2COA A;  2OTX A;  2MKR A;  2YT0 A;  1I2H A;  4D6W A;  2HTH B;  4MY6 A;  1ZVR A;  4OT1 A;  1UNR A;  3SNH A;  4A5K A;  3DCX A;  1X1F A;  2LYD A;  2K49 A;  1MKE A;  2J0K A;  3PSC A;  5JHG A;  1WGU A;  4A6F B;  1H4R A;  1X05 A;  5D3W A;  2VKI A;  2ROV A;  3UZT A;  3LJU X;  2M14 A;  1XCG A;  4GPT B;  1GC7 A;  2D9Y A;  3U7D A;  3T06 A;  3O96 A;  1FAO A;  2YS3 A;  1FB8 A;  4K2P A;  2LOX A;  2EJ8 A;  1XR0 B;  2RRF A;  3DXC A;  4BBK A;  3A58 A;  1H10 A;  4CHJ A;  5JLJ B;  2BCJ A;  1P6S A;  2EC1 A;  2P0F A;  3CIK A;  4OSN A;  1X86 A;  2RLO A;  1W1D A;  2YF0 A;  2DYQ A;  3KSY A;  2P8V A;  1BAK A;  1MIZ B;  2GCL A;  5D3Y A;  2CRF A;  2W2X D;  3HW2 B;  2Y8G A;  3HK0 A;  5HE3 A;  4CYE A;  2RSG A;  1MPH A;  3QWM A;  2RVB B;  1FHO A;  3AU5 A;  2XQN M;  1LB1 A;  3A8Q A;  2L1C A;  4WJ7 A;  2CY4 A;  1MK9 B;  4ZRK A;  3U8Z A;  2KR0 A;  3GYO A;  2DLW A;  5D27 A;  4DX8 A;  3TW1 A;  3ODO A;  2LG1 A;  1UPQ A;  1M7R A;  4TKN A;  4EMO A;  1EAZ A;  4HAV B;  3FVC A;  2Z0Q A;  1KZ7 A;  4EKU A;  5C5B B;  2KCJ A;  3GYP A;  4K81 A;  2H7E A;  2K8E A;  1J0W A;  5D3V A;  1XKE A;  1GC6 A;  5J3Q A;  2N0Y A;  1SGH A;  3V5W A;  5IRS A;  2R0D A;  2M38 A;  1Y19 B;  3CXB B;  1MAI A;  3ULB A;  3TO1 A;  1MIX A;  2YSZ A;  4DXA B;  2KIG A;  5JHH A;  2R09 A;  1WGQ A;  4GZU A;  1UNP A;  5KQ4 A;  2I5C A;  2QKL A;  3TCA A;  1PFJ A;  2DHK A;  4CHM A;  1NU2 A;  4HDO A;  1V5P A;  3SYX A;  1V5U A;  2FJL A;  4IFS A;  4B6H A;  2R2Y A;  1AQC A;  1U5F A;  4KHB B;  1DRO A;  3A98 B;  2YS5 A;  4A6K A;  1KI1 B;  1U5G A;  2ZKM X;  1BTK A;  1ZC3 B;  5FI1 A;  5M4Y B;  1WI1 A;  4C0A A;  1MI1 A;  2YVC A;  3HIE A;  2Z59 A;  4WSF A;  1FHW A;  1AWE A;  4IAP A;  2W2X C;  4A6F A;  1OMW A;  3VIA A;  3N7C A;  3PEG A;  5C6R A;  5L81 A;  1P5T A;  3FEH A;  3X23 A;  2E2X A;  5CLQ B;  3M1I B;  2CY5 A;  2YT2 A;  1MK7 B;  1V89 A;  5C79 A;  4CSQ A;  3FSS A;  3SV1 A;  4L6E A;  2AEH A;  2YRY A;  4NY0 A;  1ZSQ A;  3MPX A;  5LOP B;  2K00 A;  5LG4 B;  2UZR A;  1FGY A;  2D11 A;  3OAN A;  3VOQ A;  1V61 A;  2DKQ A;  4DX9 0;  1Y5O A;  2X18 A;  4GMV A;  1EVH A;  3ML4 A;  3B77 A;  4PNK A;  2IYB A;  1ZC4 B;  2MDX A;  2YT1 A;  2RGN B;  2L2I A;  2DX5 A;  2ADZ A;  3SO6 A;  4GXB A;  5EFX A;  3NW8 A;  5I2M A;  2MFQ A;  4ZRJ A;  4GMX B;  4HB2 B;  2Z13 A;  2Y8F A;  4KVG B;  5C16 A;  2J0M A;  1QC6 A;  1ISN A;  2K2U A;  2UVM A;  1V5M A;  1GG3 A;  1DDW A; 
#chains in the Genus database with same CATH homology
 1M7E A;  1X11 A;  2G35 A;  4HAT B;  4HAY B;  4HAX B;  2LKO A;  2YS1 A;  2D10 A;  4NSW A;  1V88 A;  1WJ1 A;  1TXD A;  2DFK A;  1NTY A;  3KRW A;  5GOW B;  5LON B;  2D2Q A;  3KZ1 A;  3MDB C;  2ELB A;  2GCJ A;  2ELA A;  2J0J A;  5C5B A;  3ODW A;  4K2O A;  1K5G B;  1PMS A;  2D4Q A;  3PZD A;  1Q67 A;  3BJI A;  2I5F A;  4F7G A;  2P0H A;  1TJ6 A;  4Z2M B;  3WYF B;  1RJ2 A;  1UNQ A;  4GN1 A;  4A6H A;  4P7I A;  2GJY A;  4F7H A;  1IRS A;  4YON A;  2LOZ A;  2Z0O A;  3RCP A;  1OQN A;  2KUP A;  2D9Z A;  3D8E A;  2QKM A;  3P7Z A;  1J19 A;  1Z87 A;  2AL6 A;  3BIN A;  4K17 A;  2LUL A;  2V76 A;  2I1K A;  2DN6 A;  1U5D A;  4DBB A;  1NI2 A;  1SHC A;  1U2B A;  2RNR B;  3IVF A;  2DTC A;  3P6A A;  1DDV A;  2CAY A;  1FOE A;  3PVU A;  3WA0 A;  1U27 A;  2VRW B;  3PVW A;  2DA0 A;  3TFM A;  3G9W A;  4KAX B;  2DKP A;  4HHV A;  2EMT A;  2K2J A;  3A8P A;  2DYN A;  2Y7B A;  3D8F A;  5CLL B;  1N3H A;  2HE7 A;  4HAZ B;  2N23 A;  1DYN A;  2COC A;  1I7A A;  4IOY X;  1W1H A;  4YL8 A;  1U5E A;  3F0W A;  1E5W A;  1WJM A;  1WVH A;  2DX1 A;  2VSZ A;  1XD4 A;  1ZM0 A;  3NSU A;  1XOD A;  5DHF B;  3QIJ A;  2COF A;  3PVL A;  3PP2 A;  5HE1 A;  5J3T A;  5FI0 A;  5HE0 A;  3F5R A;  2GS0 A;  1K5D B;  3KY9 A;  2COD A;  2P0D A;  5KCV A;  2H7D A;  2JP2 A;  2D9X A;  4F7U P;  3ZDT A;  2Z0P A;  2PZ1 A;  4XWX A;  4HAW B;  4Y94 A;  1QQG A;  1FGZ A;  1FHX A;  3FM8 C;  3DXD A;  4HB3 B;  2ZPY A;  3ODX A;  5JP4 A;  3KRX A;  4TYZ A;  1XX0 A;  2ROZ B;  3DXE A;  2IFS A;  1BWN A;  2J59 M;  1W1G A;  2W2W A;  4PQ0 A;  1WG7 A;  1DDM A;  2NMB A;  1KZG A;  2DHI A;  1RRP B;  5DHA B;  4Z2N A;  4HAU B;  1B55 A;  2NZ8 B;  3TVV A;  1LW3 A;  5HE2 A;  2MWN B;  5DIF B;  4HB4 B;  1PLS A;  3QBV B;  4EJN A;  1OY2 A;  5D3X A;  1U29 A;  4KHA A;  4MT7 A;  1UEF A;  1BTN A;  2OQB A;  4HB0 B;  2D9V A;  2DHJ A;  3PG7 A;  4D0N B;  4MK0 A;  5DH9 B;  4HDQ A;  1EGX A;  2D9W A;  4WVF B;  5DI9 B;  1DBH A;  4KHO A;  5J3Y A;  3ULC A;  1UPR A;  1NTV A;  5KQ1 A;  3AJ4 A;  4H8S A;  4ZRI A;  3SUZ A;  3AU4 A;  3D8D A;  1P3R A;  2EMS A;  2KGX B;  1X1G A;  3HQC A;  1TQZ A;  2RUK B;  1EF1 A;  2Q13 A;  2UZS A;  3ZVR A;  2I1J A;  2COA A;  2OTX A;  2MKR A;  2YT0 A;  1I2H A;  2HTH B;  4MY6 A;  1ZVR A;  1UNR A;  3SNH A;  4A5K A;  1X1F A;  2LYD A;  1MKE A;  2J0K A;  3PSC A;  5JHG A;  1WGU A;  4A6F B;  1H4R A;  1X05 A;  5D3W A;  2VKI A;  2ROV A;  3UZT A;  3LJU X;  2M14 A;  1XCG A;  4GPT B;  1GC7 A;  2D9Y A;  3U7D A;  3T06 A;  3O96 A;  1FAO A;  2YS3 A;  1FB8 A;  4K2P A;  2LOX A;  2EJ8 A;  1XR0 B;  3DXC A;  4BBK A;  1H10 A;  4CHJ A;  5JLJ B;  2BCJ A;  1P6S A;  2EC1 A;  2P0F A;  3CIK A;  1X86 A;  2RLO A;  1W1D A;  2YF0 A;  2DYQ A;  3KSY A;  2P8V A;  1BAK A;  1MIZ B;  2GCL A;  5D3Y A;  2CRF A;  2W2X D;  3HW2 B;  2Y8G A;  3HK0 A;  5HE3 A;  4CYE A;  2RSG A;  1MPH A;  3QWM A;  2RVB B;  1FHO A;  3AU5 A;  2XQN M;  1LB1 A;  3A8Q A;  2L1C A;  4WJ7 A;  2CY4 A;  1MK9 B;  4ZRK A;  3U8Z A;  3GYO A;  2DLW A;  5D27 A;  4DX8 A;  3TW1 A;  3ODO A;  2LG1 A;  1UPQ A;  1M7R A;  4TKN A;  4EMO A;  1EAZ A;  4HAV B;  2Z0Q A;  1KZ7 A;  4EKU A;  5C5B B;  2KCJ A;  3GYP A;  4K81 A;  2H7E A;  1J0W A;  5D3V A;  1XKE A;  1GC6 A;  5J3Q A;  2N0Y A;  1SGH A;  3V5W A;  2R0D A;  2M38 A;  1Y19 B;  3CXB B;  1MAI A;  3ULB A;  3TO1 A;  1MIX A;  2YSZ A;  4DXA B;  5JHH A;  2R09 A;  1WGQ A;  4GZU A;  1UNP A;  5KQ4 A;  2I5C A;  2QKL A;  3TCA A;  1PFJ A;  2DHK A;  4CHM A;  1NU2 A;  4HDO A;  1V5P A;  3SYX A;  1V5U A;  2FJL A;  4IFS A;  4B6H A;  1AQC A;  1U5F A;  4KHB B;  1DRO A;  3A98 B;  2YS5 A;  4A6K A;  1KI1 B;  1U5G A;  1BTK A;  1ZC3 B;  5FI1 A;  1WI1 A;  4C0A A;  2YVC A;  4WSF A;  1FHW A;  1AWE A;  4IAP A;  2W2X C;  4A6F A;  1OMW A;  3VIA A;  3N7C A;  3PEG A;  5C6R A;  5L81 A;  1P5T A;  3FEH A;  3X23 A;  2E2X A;  5CLQ B;  3M1I B;  2CY5 A;  1MK7 B;  1V89 A;  5C79 A;  3FSS A;  3SV1 A;  4L6E A;  2AEH A;  2YRY A;  4NY0 A;  1ZSQ A;  3MPX A;  5LOP B;  2K00 A;  2UZR A;  1FGY A;  2D11 A;  3OAN A;  3VOQ A;  1V61 A;  2DKQ A;  4DX9 0;  1Y5O A;  2X18 A;  4GMV A;  1EVH A;  3ML4 A;  4PNK A;  2IYB A;  1ZC4 B;  2MDX A;  2YT1 A;  2RGN B;  2L2I A;  2DX5 A;  2ADZ A;  3SO6 A;  4GXB A;  5EFX A;  2MFQ A;  4ZRJ A;  4GMX B;  4HB2 B;  2Y8F A;  4KVG B;  5C16 A;  2J0M A;  1QC6 A;  1ISN A;  2K2U A;  2UVM A;  1V5M A;  1GG3 A;  1DDW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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