4K2PA

The structure of a quintuple mutant of the tiam1 ph-cc-ex domain
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
238
structure length
238
Chain Sequence
TVRKAGALAVKNFLVHKKNKKVESATRRKWKHYWVSLKGCTLFFYESDGRSGIDHNSIPKHAVWVENSIVQAVPEHPKKDFVFCLSNSLGDAFLFQTTSQTELENWITAIHSACATAVARHHHKEDTLRLLKSEIKKLEQKIDMDEKLKKMGELQLSSVTDSKAAATILDQIFVWEQNLEQFQMDLFRFRCYLASLQGGELPNPKRLLAFASRPTKVAMGRLGIFSVSSFHALVAART
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords T-lymphoma invasion and metastasis-inducing protein 1
publication title High-resolution structure of the Tiam1 PHn-CC-Ex domain.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Signaling protein
total genus 78
structure length 238
sequence length 238
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-04-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF18385 Tiam_CC_Ex T-lymphoma invasion and metastasis CC-Ex domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 4k2pA01
4WSFA 2Z0QA 3HQCA 4F7GA 5D3WA 3KZ1A 2HTHB 2OQBA 2DN6A 4TKNA 5D3XA 2MWNB 1WG7A 1TXDA 4A6FA 1FHOA 4ZRIA 4WJ7A 1WJMA 2PZ1A 1QQGA 2W2XD 2Y8GA 1KZGA 3PVUA 1M7RA 5CLLB 5J3YA 2LG1A 1Y5OA 5DHFB 4A6FB 2RVBB 2D4QA 2D11A 1XD4A 2DFKA 1GG3A 2YSZA 5EFXA 1FHWA 4EKUA 2J59M 2D9WA 2R0DA 3FSSA 3KRWA 2Z0PA 2NZ8B 1WGUA 5JHGA 4A6KA 1NTVA 5C16A 4NSWA 4B6HA 2RGNB 4HAUB 3VOQA 1PFJA 1N3HA 4IAPA 4C0AA 1J19A 1FOEA 2IFSA 3CIKA 2I1KA 2H7DA 1MK9B 2ELBA 1XCGA 3O96A 4NY0A 1MIZB 2ZPYA 2DHIA 5JHHA 5C5BA 1DDVA 4DX8A 2YRYA 2EMSA 3AU5A 1W1DA 4K17A 1XKEA 2AEHA 1DDMA 5HE1A 1K5GB 3IVFA 2QKMA 2P0FA 4Y94A 5C5BB 1DROA 3LJUX 1FAOA 3AJ4A 4HDQA 4MK0A 2MKRA 5KQ1A 2DHKA 2ROVA 2Q13A 2ROZB 4KHAA 1RRPB 1ZSQA 2Z0OA 1U2BA 1MK7B 2VRWB 1Y19B 2GJYA 5HE0A 3WYFB 2ADZA 3OANA 1ZC4B 1M7EA 4PQ0A 1UNRA 4EMOA 3A8PA 3TW1A 2P0DA 3ODWA 2EJ8A 2YVCA 1V5UA 1OMWA 1UNQA 1FGYA 4HB2B 4HAYB 3SYXA 3P7ZA 3DXDA 1PLSA 2V76A 1IRSA 1TJ6A 3P6AA 1XX0A 4KHBB 4K81A 1BTNA 2RUKB 4WVFB 5JLJB 1U27A 5L81A 2COCA 2COFA 3BINA 1V61A 4HDOA 2HE7A 3KY9A 4ZRKA 1XR0B 2ELAA 4EJNA 4IFSA 2DLWA 1X11A 4CYEA 5LOPB 2D10A 1BWNA 3D8FA 2W2WA 4HB3B 5DH9B 3U7DA 2RSGA 1FGZA 1QC6A 1WVHA 2M38A 2AL6A 2YS1A 3PZDA 4GXBA 1BTKA 2YT0A 2LULA 2DKPA 1AWEA 4H8SA 3GYOA 2QKLA 2G35A 5LONB 3ML4A 2L2IA 1WGQA 4A5KA 2D9XA 4DX90 4D0NB 2D2QA 2R09A 1WI1A 2UZSA 1DBHA 3N7CA 2UZRA 5KQ4A 2DX5A 1UPRA 2NMBA 2VKIA 2YS3A 4BBKA 1UEFA 3MDBC 4KHOA 3DXEA 1AQCA 2K2UA 3V5WA 4HB4B 2YF0A 3ZDTA 4CHMA 3NSUA 3TFMA 5C6RA 1NU2A 4DXAB 4GMVA 1H10A 1WJ1A 2L1CA 5DHAB 1EGXA 2I1JA 3AU4A 2GCJA 2OTXA 2J0KA 2UVMA 3PVLA 4TYZA 1V89A 2COAA 2DHJA 2LYDA 3SNHA 3MPXA 4YL8A 4MT7A 3KRXA 2D9VA 1ZC3B 3ULBA 5D3YA 1H4RA 1P6SA 2LKOA 1ISNA 2EMTA 1X05A 4HAWB 2VSZA 1EVHA 3ODXA 2M14A 1FHXA 1X1FA 2YT1A 5HE2A 3SUZA 3PG7A 3FEHA 3TVVA 2MFQA 2D9YA 5J3QA 3F5RA 1EAZA 3BJIA 3D8EA 3PEGA 4HAXB 1MIXA 2KUPA 2P8VA 2Y8FA 2J0MA 3SV1A 5GOWB 4P7IA 2DA0A 1I2HA 3G9WA 1SHCA 1Z87A 1U5FA 1DDWA 5J3TA 1X1GA 1SGHA 1FB8A 1U5EA 3VIAA 1U5DA 2RLOA 2MDXA 4GPTB 1EF1A 2CY5A 4K2OA 3HK0A 1NTYA 3PVWA 4Z2MB 1PMSA 2H7EA 2X18A 3ZVRA 3ULCA 2CRFA 4Z2NA 4ZRJA 1RJ2A 3TCAA 1E5WA 4F7UP 2D9ZA 1MPHA 4HB0B 2GS0A 4HAVB 2CAYA 2DKQA 5D3VA 1LW3A 1ZVRA 1BAKA 2KGXB 4K2PA 3TO1A 1J0WA 3QIJA 5FI0A 3PSCA 1OQNA 3D8DA 3RCPA 3DXCA 5JP4A 4GMXB 3X23A 1NI2A 4MY6A 2JP2A 4F7HA 1LB1A 2I5FA 2DX1A 1UPQA 2KCJA 4IOYX 3U8ZA 2DYQA 2EC1A 2DTCA 2RNRB 1DYNA 2P0HA 1KZ7A 4A6HA 3CXBB 5DI9B 4DBBA 1U5GA 1TQZA 2K2JA 3A8QA 2J0JA 2FJLA 4YONA 3WA0A 4HAZB 3A98B 5CLQB 1Q67A 4L6EA 2K00A 4HATB 2BCJA 4CHJA 1V88A 3FM8C 1ZM0A 2LOXA 3UZTA 1GC7A 3QBVB 4HHVA 2XQNM 1K5DB 3HW2B 4KVGB 1X86A 2CODA 1I7AA 1GC6A 1KI1B 2CY4A 2GCLA 1W1HA 1UNPA 5HE3A 4PNKA 5KCVA 2E2XA 2DYNA 3SO6A 2N23A 1OY2A 4GN1A 3F0WA 1XODA 3M1IB 3QWMA 3PP2A 1B55A 1P5TA 1W1GA 2I5CA 3GYPA 3KSYA 5DIFB 2W2XC 5D27A 2Y7BA 2N0YA 3ODOA 3T06A 1U29A 2IYBA 1P3RA 4KAXB 2YS5A 1V5PA 1MAIA 2LOZA 1V5MA 5C79A 1MKEA 4GZUA 5FI1A 4XWXA
chains in the Genus database with same CATH superfamily
4WSFA 2Z0QA 3HQCA 4F7GA 5D3WA 3KZ1A 3U12A 2HTHB 2OQBA 2DN6A 4TKNA 5D3XA 2MWNB 1WG7A 1TXDA 4A6FA 1FHOA 4ZRIA 4WJ7A 1WJMA 2PZ1A 1QQGA 2W2XD 2Y8GA 1KZGA 3PVUA 1M7RA 3OHMB 5CLLB 5J3YA 2LG1A 1Y5OA 5DHFB 4A6FB 2RVBB 2D4QA 2D11A 1XD4A 2DFKA 1GG3A 2YSZA 5EFXA 1FHWA 4EKUA 2J59M 2D9WA 2R0DA 3FVCA 3FSSA 3KRWA 2Z0PA 4QJ3B 2NZ8B 3A58A 1WGUA 5JHGA 4A6KA 1NTVA 5C16A 4NSWA 2KR0A 4B6HA 2RGNB 4HAUB 3VOQA 1PFJA 1N3HA 4IAPA 4C0AA 5I2SA 1J19A 1FOEA 2GUMA 2IFSA 3B77A 3CIKA 2I1KA 2H7DA 1MK9B 2ELBA 1XCGA 4QJ5B 3O96A 2YT2A 4NY0A 1MIZB 2ZPYA 2DHIA 5M4YB 5JHHA 5C5BA 1DDVA 4DX8A 2YRYA 2EMSA 3AU5A 1W1DA 4K17A 1XKEA 2AEHA 1DDMA 3NWFA 5HE1A 1K5GB 2R2YA 3IVFA 3HIEA 2QKMA 2P0FA 4Y94A 5C5BB 1DROA 3LJUX 1FAOA 3AJ4A 4HDQA 4MK0A 2MKRA 5KQ1A 2DHKA 2ROVA 2Q13A 2ROZB 4KHAA 1RRPB 1ZSQA 2Z0OA 1U2BA 1MK7B 2VRWB 1Y19B 2GJYA 5HE0A 3WYFB 2ADZA 3OANA 1ZC4B 1M7EA 4PQ0A 1UNRA 4EMOA 3A8PA 3TW1A 2P0DA 3ODWA 2EJ8A 1T77A 4KHBA 2YVCA 1V5UA 1OMWA 1UNQA 1FGYA 4HB2B 3HSAA 4HAYB 3SYXA 3P7ZA 3DXDA 1PLSA 2V76A 1IRSA 1TJ6A 3P6AA 1XX0A 2Z4DA 4KHBB 4K81A 1BTNA 2RUKB 4WVFB 4OSNA 5JLJB 1U27A 5L81A 2COCA 4HSIA 2COFA 3BINA 4L1RA 1V61A 4HDOA 2HE7A 3KY9A 4ZRKA 4OT1A 1XR0B 2ELAA 2ZKMX 4EJNA 4IFSA 2DLWA 1X11A 3NW8A 4CYEA 5LOPB 2D10A 1BWNA 3D8FA 2W2WA 4HB3B 5DH9B 3U7DA 2RSGA 1FGZA 1QC6A 1WVHA 2M38A 2AL6A 2YS1A 3PZDA 4GXBA 1BTKA 2YT0A 2LULA 2NBVA 2DKPA 1AWEA 4H8SA 3GYOA 2QKLA 2G35A 5LG4B 5LONB 3ML4A 2L2IA 1WGQA 4A5KA 2D9XA 4DX90 2Z59A 4D0NB 2D2QA 2R09A 3DCXA 1WI1A 2UZSA 1DBHA 3N7CA 2UZRA 5KQ4A 2DX5A 2KUQA 1UPRA 2NMBA 2VKIA 2YS3A 4BBKA 1UEFA 3MDBC 4KHOA 3DXEA 1AQCA 2K2UA 3V5WA 4HB4B 2YF0A 3ZDTA 4CSQA 4CHMA 3NSUA 3TFMA 5C6RA 1NU2A 4QXAB 4DXAB 4GMVA 1H10A 1WJ1A 2L1CA 5DHAB 1EGXA 2I1JA 3AU4A 2GCJA 2OTXA 2J0KA 2UVMA 3PVLA 4TYZA 1V89A 2COAA 2DHJA 2LYDA 3SNHA 3MPXA 4YL8A 4MT7A 3KRXA 2D9VA 1ZC3B 3ULBA 5D3YA 1H4RA 1P6SA 2LKOA 1ISNA 2EMTA 1X05A 4HAWB 2VSZA 1EVHA 3ODXA 2M14A 5IRSA 2Z13A 1FHXA 4D6WA 1X1FA 2YT1A 5HE2A 3SUZA 3PG7A 3FEHA 3TVVA 2MFQA 2D9YA 5J3QA 3F5RA 1EAZA 3BJIA 3D8EA 3PEGA 4HAXB 1MIXA 2KUPA 2P8VA 3NWAA 2Y8FA 2J0MA 3SV1A 5GOWB 4P7IA 2DA0A 1I2HA 3G9WA 1SHCA 1Z87A 1U5FA 1DDWA 5J3TA 1X1GA 1SGHA 1FB8A 1U5EA 3VIAA 1U5DA 4GOUA 2RLOA 2MDXA 4GPTB 2FJUB 1EF1A 2CY5A 4K2OA 3HK0A 1NTYA 3PVWA 4Z2MB 1ZYIA 1PMSA 2H7EA 2X18A 3ZVRA 3ULCA 1MI1A 2CRFA 4Z2NA 4ZRJA 1RJ2A 3TCAA 1E5WA 4F7UP 2D9ZA 1MPHA 4HB0B 2GS0A 4HAVB 2CAYA 2DKQA 5D3VA 4DIXA 1LW3A 1ZVRA 1BAKA 2KGXB 4K2PA 3TO1A 1J0WA 2K8EA 3QIJA 5FI0A 3PSCA 1OQNA 3D8DA 3RCPA 3DXCA 5JP4A 2K49A 4GMXB 3X23A 1NI2A 4MY6A 2JP2A 4F7HA 1LB1A 2I5FA 4GNKB 2DX1A 1UPQA 2KCJA 4IOYX 3U8ZA 2DYQA 2EC1A 2DTCA 2RNRB 1DYNA 2P0HA 1KZ7A 4A6HA 3CXBB 5DI9B 4DBBA 1U5GA 1TQZA 2K2JA 3A8QA 2J0JA 2FJLA 4YONA 3WA0A 4HAZB 3A98B 5CLQB 1Q67A 4L6EA 2K00A 4HATB 2BCJA 4CHJA 1V88A 3FM8C 1ZM0A 2LOXA 3UZTA 1GC7A 3QBVB 4HHVA 2XQNM 1K5DB 3HW2B 4KVGB 1X86A 2CODA 1I7AA 1GC6A 1KI1B 2CY4A 2GCLA 1W1HA 1UNPA 5I2MA 5HE3A 4PNKA 4QJ4B 5KCVA 2E2XA 2DYNA 2RRFA 3SO6A 2N23A 1OY2A 4GN1A 3NWDA 2KIGA 1XODA 3F0WA 3M1IB 3QWMA 3PP2A 1B55A 2KIEA 1P5TA 1W1GA 2I5CA 3GYPA 3KSYA 5DIFB 2W2XC 5D27A 2Y7BA 2N0YA 3ODOA 3T06A 1U29A 2IYBA 2Z14A 1P3RA 4KAXB 2YS5A 1V5PA 1MAIA 2LOZA 1V5MA 5C79A 1MKEA 4GZUA 5FI1A 4XWXA
chains in the Genus database with same CATH topology
4WSFA 2Z0QA 3HQCA 4F7GA 5D3WA 3KZ1A 2HTHB 2OQBA 2DN6A 4TKNA 5D3XA 2MWNB 1WG7A 1TXDA 4A6FA 1FHOA 4ZRIA 4WJ7A 1WJMA 2PZ1A 1QQGA 2W2XD 2Y8GA 1KZGA 3PVUA 1M7RA 5CLLB 5J3YA 2LG1A 1Y5OA 5DHFB 4A6FB 2RVBB 2D4QA 2D11A 1XD4A 2DFKA 1GG3A 2YSZA 5EFXA 1FHWA 4EKUA 2J59M 2D9WA 2R0DA 3FSSA 3KRWA 2Z0PA 2NZ8B 1WGUA 5JHGA 4A6KA 1NTVA 5C16A 4NSWA 4B6HA 2RGNB 4HAUB 3VOQA 1PFJA 1N3HA 4IAPA 4C0AA 1J19A 1FOEA 2IFSA 3CIKA 2I1KA 2H7DA 1MK9B 2ELBA 1XCGA 3O96A 4NY0A 1MIZB 2ZPYA 2DHIA 5JHHA 5C5BA 1DDVA 4DX8A 2YRYA 2EMSA 3AU5A 1W1DA 4K17A 1XKEA 2AEHA 1DDMA 5HE1A 1K5GB 3IVFA 2QKMA 2P0FA 4Y94A 5C5BB 1DROA 3LJUX 1FAOA 3AJ4A 4HDQA 4MK0A 2MKRA 5KQ1A 2DHKA 2ROVA 2Q13A 2ROZB 4KHAA 1RRPB 1ZSQA 2Z0OA 1U2BA 1MK7B 2VRWB 1Y19B 2GJYA 5HE0A 3WYFB 2ADZA 3OANA 1ZC4B 1M7EA 4PQ0A 1UNRA 4EMOA 3A8PA 3TW1A 2P0DA 3ODWA 2EJ8A 2YVCA 1V5UA 1OMWA 1UNQA 1FGYA 4HB2B 4HAYB 3SYXA 3P7ZA 3DXDA 1PLSA 2V76A 1IRSA 1TJ6A 3P6AA 1XX0A 4KHBB 4K81A 1BTNA 2RUKB 4WVFB 5JLJB 1U27A 5L81A 2COCA 2COFA 3BINA 1V61A 4HDOA 2HE7A 3KY9A 4ZRKA 1XR0B 2ELAA 4EJNA 4IFSA 2DLWA 1X11A 4CYEA 5LOPB 2D10A 1BWNA 3D8FA 2W2WA 4HB3B 5DH9B 3U7DA 2RSGA 1FGZA 1QC6A 1WVHA 2M38A 2AL6A 2YS1A 3PZDA 4GXBA 1BTKA 2YT0A 2LULA 2DKPA 1AWEA 4H8SA 3GYOA 2QKLA 2G35A 5LONB 3ML4A 2L2IA 1WGQA 4A5KA 2D9XA 4DX90 4D0NB 2D2QA 2R09A 1WI1A 2UZSA 1DBHA 3N7CA 2UZRA 5KQ4A 2DX5A 1UPRA 2NMBA 2VKIA 2YS3A 4BBKA 1UEFA 3MDBC 4KHOA 3DXEA 1AQCA 2K2UA 3V5WA 4HB4B 2YF0A 3ZDTA 4CHMA 3NSUA 3TFMA 5C6RA 1NU2A 4DXAB 4GMVA 1H10A 1WJ1A 2L1CA 5DHAB 1EGXA 2I1JA 3AU4A 2GCJA 2OTXA 2J0KA 2UVMA 3PVLA 4TYZA 1V89A 2COAA 2DHJA 2LYDA 3SNHA 3MPXA 4YL8A 4MT7A 3KRXA 2D9VA 1ZC3B 3ULBA 5D3YA 1H4RA 1P6SA 2LKOA 1ISNA 2EMTA 1X05A 4HAWB 2VSZA 1EVHA 3ODXA 2M14A 1FHXA 1X1FA 2YT1A 5HE2A 3SUZA 3PG7A 3FEHA 3TVVA 2MFQA 2D9YA 5J3QA 3F5RA 1EAZA 3BJIA 3D8EA 3PEGA 4HAXB 1MIXA 2KUPA 2P8VA 2Y8FA 2J0MA 3SV1A 5GOWB 4P7IA 2DA0A 1I2HA 3G9WA 1SHCA 1Z87A 1U5FA 1DDWA 5J3TA 1X1GA 1SGHA 1FB8A 1U5EA 3VIAA 1U5DA 2RLOA 2MDXA 4GPTB 1EF1A 2CY5A 4K2OA 3HK0A 1NTYA 3PVWA 4Z2MB 1PMSA 2H7EA 2X18A 3ZVRA 3ULCA 2CRFA 4Z2NA 4ZRJA 1RJ2A 3TCAA 1E5WA 4F7UP 2D9ZA 1MPHA 4HB0B 2GS0A 4HAVB 2CAYA 2DKQA 5D3VA 1LW3A 1ZVRA 1BAKA 2KGXB 4K2PA 3TO1A 1J0WA 3QIJA 5FI0A 3PSCA 1OQNA 3D8DA 3RCPA 3DXCA 5JP4A 4GMXB 3X23A 1NI2A 4MY6A 2JP2A 4F7HA 1LB1A 2I5FA 2DX1A 1UPQA 2KCJA 4IOYX 3U8ZA 2DYQA 2EC1A 2DTCA 2RNRB 1DYNA 2P0HA 1KZ7A 4A6HA 3CXBB 5DI9B 4DBBA 1U5GA 1TQZA 2K2JA 3A8QA 2J0JA 2FJLA 4YONA 3WA0A 4HAZB 3A98B 5CLQB 1Q67A 4L6EA 2K00A 4HATB 2BCJA 4CHJA 1V88A 3FM8C 1ZM0A 2LOXA 3UZTA 1GC7A 3QBVB 4HHVA 2XQNM 1K5DB 3HW2B 4KVGB 1X86A 2CODA 1I7AA 1GC6A 1KI1B 2CY4A 2GCLA 1W1HA 1UNPA 5HE3A 4PNKA 5KCVA 2E2XA 2DYNA 3SO6A 2N23A 1OY2A 4GN1A 3F0WA 1XODA 3M1IB 3QWMA 3PP2A 1B55A 1P5TA 1W1GA 2I5CA 3GYPA 3KSYA 5DIFB 2W2XC 5D27A 2Y7BA 2N0YA 3ODOA 3T06A 1U29A 2IYBA 1P3RA 4KAXB 2YS5A 1V5PA 1MAIA 2LOZA 1V5MA 5C79A 1MKEA 4GZUA 5FI1A 4XWXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WSF A;  2Z0Q A;  3HQC A;  4F7G A;  5D3W A;  3KZ1 A;  2HTH B;  2OQB A;  2DN6 A;  4TKN A;  5D3X A;  2MWN B;  1WG7 A;  1TXD A;  4A6F A;  1FHO A;  4ZRI A;  4WJ7 A;  1WJM A;  2PZ1 A;  1QQG A;  2W2X D;  2Y8G A;  1KZG A;  3PVU A;  1M7R A;  5CLL B;  5J3Y A;  2LG1 A;  1Y5O A;  5DHF B;  4A6F B;  2RVB B;  2D4Q A;  2D11 A;  1XD4 A;  2DFK A;  1GG3 A;  2YSZ A;  5EFX A;  1FHW A;  4EKU A;  2J59 M;  2D9W A;  2R0D A;  3FSS A;  3KRW A;  2Z0P A;  2NZ8 B;  1WGU A;  5JHG A;  4A6K A;  1NTV A;  5C16 A;  4NSW A;  4B6H A;  2RGN B;  4HAU B;  3VOQ A;  1PFJ A;  1N3H A;  4IAP A;  4C0A A;  1J19 A;  1FOE A;  2IFS A;  3CIK A;  2I1K A;  2H7D A;  1MK9 B;  2ELB A;  1XCG A;  3O96 A;  4NY0 A;  1MIZ B;  2ZPY A;  2DHI A;  5JHH A;  5C5B A;  1DDV A;  4DX8 A;  2YRY A;  2EMS A;  3AU5 A;  1W1D A;  4K17 A;  1XKE A;  2AEH A;  1DDM A;  5HE1 A;  1K5G B;  3IVF A;  2QKM A;  2P0F A;  4Y94 A;  5C5B B;  1DRO A;  3LJU X;  1FAO A;  3AJ4 A;  4HDQ A;  4MK0 A;  2MKR A;  5KQ1 A;  2DHK A;  2ROV A;  2Q13 A;  2ROZ B;  4KHA A;  1RRP B;  1ZSQ A;  2Z0O A;  1U2B A;  1MK7 B;  2VRW B;  1Y19 B;  2GJY A;  5HE0 A;  3WYF B;  2ADZ A;  3OAN A;  1ZC4 B;  1M7E A;  4PQ0 A;  1UNR A;  4EMO A;  3A8P A;  3TW1 A;  2P0D A;  3ODW A;  2EJ8 A;  2YVC A;  1V5U A;  1OMW A;  1UNQ A;  1FGY A;  4HB2 B;  4HAY B;  3SYX A;  3P7Z A;  3DXD A;  1PLS A;  2V76 A;  1IRS A;  1TJ6 A;  3P6A A;  1XX0 A;  4KHB B;  4K81 A;  1BTN A;  2RUK B;  4WVF B;  5JLJ B;  1U27 A;  5L81 A;  2COC A;  2COF A;  3BIN A;  1V61 A;  4HDO A;  2HE7 A;  3KY9 A;  4ZRK A;  1XR0 B;  2ELA A;  4EJN A;  4IFS A;  2DLW A;  1X11 A;  4CYE A;  5LOP B;  2D10 A;  1BWN A;  3D8F A;  2W2W A;  4HB3 B;  5DH9 B;  3U7D A;  2RSG A;  1FGZ A;  1QC6 A;  1WVH A;  2M38 A;  2AL6 A;  2YS1 A;  3PZD A;  4GXB A;  1BTK A;  2YT0 A;  2LUL A;  2DKP A;  1AWE A;  4H8S A;  3GYO A;  2QKL A;  2G35 A;  5LON B;  3ML4 A;  2L2I A;  1WGQ A;  4A5K A;  2D9X A;  4DX9 0;  4D0N B;  2D2Q A;  2R09 A;  1WI1 A;  2UZS A;  1DBH A;  3N7C A;  2UZR A;  5KQ4 A;  2DX5 A;  1UPR A;  2NMB A;  2VKI A;  2YS3 A;  4BBK A;  1UEF A;  3MDB C;  4KHO A;  3DXE A;  1AQC A;  2K2U A;  3V5W A;  4HB4 B;  2YF0 A;  3ZDT A;  4CHM A;  3NSU A;  3TFM A;  5C6R A;  1NU2 A;  4DXA B;  4GMV A;  1H10 A;  1WJ1 A;  2L1C A;  5DHA B;  1EGX A;  2I1J A;  3AU4 A;  2GCJ A;  2OTX A;  2J0K A;  2UVM A;  3PVL A;  4TYZ A;  1V89 A;  2COA A;  2DHJ A;  2LYD A;  3SNH A;  3MPX A;  4YL8 A;  4MT7 A;  3KRX A;  2D9V A;  1ZC3 B;  3ULB A;  5D3Y A;  1H4R A;  1P6S A;  2LKO A;  1ISN A;  2EMT A;  1X05 A;  4HAW B;  2VSZ A;  1EVH A;  3ODX A;  2M14 A;  1FHX A;  1X1F A;  2YT1 A;  5HE2 A;  3SUZ A;  3PG7 A;  3FEH A;  3TVV A;  2MFQ A;  2D9Y A;  5J3Q A;  3F5R A;  1EAZ A;  3BJI A;  3D8E A;  3PEG A;  4HAX B;  1MIX A;  2KUP A;  2P8V A;  2Y8F A;  2J0M A;  3SV1 A;  5GOW B;  4P7I A;  2DA0 A;  1I2H A;  3G9W A;  1SHC A;  1Z87 A;  1U5F A;  1DDW A;  5J3T A;  1X1G A;  1SGH A;  1FB8 A;  1U5E A;  3VIA A;  1U5D A;  2RLO A;  2MDX A;  4GPT B;  1EF1 A;  2CY5 A;  4K2O A;  3HK0 A;  1NTY A;  3PVW A;  4Z2M B;  1PMS A;  2H7E A;  2X18 A;  3ZVR A;  3ULC A;  2CRF A;  4Z2N A;  4ZRJ A;  1RJ2 A;  3TCA A;  1E5W A;  4F7U P;  2D9Z A;  1MPH A;  4HB0 B;  2GS0 A;  4HAV B;  2CAY A;  2DKQ A;  5D3V A;  1LW3 A;  1ZVR A;  1BAK A;  2KGX B;  4K2P A;  3TO1 A;  1J0W A;  3QIJ A;  5FI0 A;  3PSC A;  1OQN A;  3D8D A;  3RCP A;  3DXC A;  5JP4 A;  4GMX B;  3X23 A;  1NI2 A;  4MY6 A;  2JP2 A;  4F7H A;  1LB1 A;  2I5F A;  2DX1 A;  1UPQ A;  2KCJ A;  4IOY X;  3U8Z A;  2DYQ A;  2EC1 A;  2DTC A;  2RNR B;  1DYN A;  2P0H A;  1KZ7 A;  4A6H A;  3CXB B;  5DI9 B;  4DBB A;  1U5G A;  1TQZ A;  2K2J A;  3A8Q A;  2J0J A;  2FJL A;  4YON A;  3WA0 A;  4HAZ B;  3A98 B;  5CLQ B;  1Q67 A;  4L6E A;  2K00 A;  4HAT B;  2BCJ A;  4CHJ A;  1V88 A;  3FM8 C;  1ZM0 A;  2LOX A;  3UZT A;  1GC7 A;  3QBV B;  4HHV A;  2XQN M;  1K5D B;  3HW2 B;  4KVG B;  1X86 A;  2COD A;  1I7A A;  1GC6 A;  1KI1 B;  2CY4 A;  2GCL A;  1W1H A;  1UNP A;  5HE3 A;  4PNK A;  5KCV A;  2E2X A;  2DYN A;  3SO6 A;  2N23 A;  1OY2 A;  4GN1 A;  3F0W A;  1XOD A;  3M1I B;  3QWM A;  3PP2 A;  1B55 A;  1P5T A;  1W1G A;  2I5C A;  3GYP A;  3KSY A;  5DIF B;  2W2X C;  5D27 A;  2Y7B A;  2N0Y A;  3ODO A;  3T06 A;  1U29 A;  2IYB A;  1P3R A;  4KAX B;  2YS5 A;  1V5P A;  1MAI A;  2LOZ A;  1V5M A;  5C79 A;  1MKE A;  4GZU A;  5FI1 A;  4XWX A; 
#chains in the Genus database with same CATH topology
 4WSF A;  2Z0Q A;  3HQC A;  4F7G A;  5D3W A;  3KZ1 A;  3U12 A;  2HTH B;  2OQB A;  2DN6 A;  4TKN A;  5D3X A;  2MWN B;  1WG7 A;  1TXD A;  4A6F A;  1FHO A;  4ZRI A;  4WJ7 A;  1WJM A;  2PZ1 A;  1QQG A;  2W2X D;  2Y8G A;  1KZG A;  3PVU A;  1M7R A;  3OHM B;  5CLL B;  5J3Y A;  2LG1 A;  1Y5O A;  5DHF B;  4A6F B;  2RVB B;  2D4Q A;  2D11 A;  1XD4 A;  2DFK A;  1GG3 A;  2YSZ A;  5EFX A;  1FHW A;  4EKU A;  2J59 M;  2D9W A;  2R0D A;  3FVC A;  3FSS A;  3KRW A;  2Z0P A;  4QJ3 B;  2NZ8 B;  3A58 A;  1WGU A;  5JHG A;  4A6K A;  1NTV A;  5C16 A;  4NSW A;  2KR0 A;  4B6H A;  2RGN B;  4HAU B;  3VOQ A;  1PFJ A;  1N3H A;  4IAP A;  4C0A A;  5I2S A;  1J19 A;  1FOE A;  2GUM A;  2IFS A;  3B77 A;  3CIK A;  2I1K A;  2H7D A;  1MK9 B;  2ELB A;  1XCG A;  4QJ5 B;  3O96 A;  2YT2 A;  4NY0 A;  1MIZ B;  2ZPY A;  2DHI A;  5M4Y B;  5JHH A;  5C5B A;  1DDV A;  4DX8 A;  2YRY A;  2EMS A;  3AU5 A;  1W1D A;  4K17 A;  1XKE A;  2AEH A;  1DDM A;  3NWF A;  5HE1 A;  1K5G B;  2R2Y A;  3IVF A;  3HIE A;  2QKM A;  2P0F A;  4Y94 A;  5C5B B;  1DRO A;  3LJU X;  1FAO A;  3AJ4 A;  4HDQ A;  4MK0 A;  2MKR A;  5KQ1 A;  2DHK A;  2ROV A;  2Q13 A;  2ROZ B;  4KHA A;  1RRP B;  1ZSQ A;  2Z0O A;  1U2B A;  1MK7 B;  2VRW B;  1Y19 B;  2GJY A;  5HE0 A;  3WYF B;  2ADZ A;  3OAN A;  1ZC4 B;  1M7E A;  4PQ0 A;  1UNR A;  4EMO A;  3A8P A;  3TW1 A;  2P0D A;  3ODW A;  2EJ8 A;  1T77 A;  4KHB A;  2YVC A;  1V5U A;  1OMW A;  1UNQ A;  1FGY A;  4HB2 B;  3HSA A;  4HAY B;  3SYX A;  3P7Z A;  3DXD A;  1PLS A;  2V76 A;  1IRS A;  1TJ6 A;  3P6A A;  1XX0 A;  2Z4D A;  4KHB B;  4K81 A;  1BTN A;  2RUK B;  4WVF B;  4OSN A;  5JLJ B;  1U27 A;  5L81 A;  2COC A;  4HSI A;  2COF A;  3BIN A;  4L1R A;  1V61 A;  4HDO A;  2HE7 A;  3KY9 A;  4ZRK A;  4OT1 A;  1XR0 B;  2ELA A;  2ZKM X;  4EJN A;  4IFS A;  2DLW A;  1X11 A;  3NW8 A;  4CYE A;  5LOP B;  2D10 A;  1BWN A;  3D8F A;  2W2W A;  4HB3 B;  5DH9 B;  3U7D A;  2RSG A;  1FGZ A;  1QC6 A;  1WVH A;  2M38 A;  2AL6 A;  2YS1 A;  3PZD A;  4GXB A;  1BTK A;  2YT0 A;  2LUL A;  2NBV A;  2DKP A;  1AWE A;  4H8S A;  3GYO A;  2QKL A;  2G35 A;  5LG4 B;  5LON B;  3ML4 A;  2L2I A;  1WGQ A;  4A5K A;  2D9X A;  4DX9 0;  2Z59 A;  4D0N B;  2D2Q A;  2R09 A;  3DCX A;  1WI1 A;  2UZS A;  1DBH A;  3N7C A;  2UZR A;  5KQ4 A;  2DX5 A;  2KUQ A;  1UPR A;  2NMB A;  2VKI A;  2YS3 A;  4BBK A;  1UEF A;  3MDB C;  4KHO A;  3DXE A;  1AQC A;  2K2U A;  3V5W A;  4HB4 B;  2YF0 A;  3ZDT A;  4CSQ A;  4CHM A;  3NSU A;  3TFM A;  5C6R A;  1NU2 A;  4QXA B;  4DXA B;  4GMV A;  1H10 A;  1WJ1 A;  2L1C A;  5DHA B;  1EGX A;  2I1J A;  3AU4 A;  2GCJ A;  2OTX A;  2J0K A;  2UVM A;  3PVL A;  4TYZ A;  1V89 A;  2COA A;  2DHJ A;  2LYD A;  3SNH A;  3MPX A;  4YL8 A;  4MT7 A;  3KRX A;  2D9V A;  1ZC3 B;  3ULB A;  5D3Y A;  1H4R A;  1P6S A;  2LKO A;  1ISN A;  2EMT A;  1X05 A;  4HAW B;  2VSZ A;  1EVH A;  3ODX A;  2M14 A;  5IRS A;  2Z13 A;  1FHX A;  4D6W A;  1X1F A;  2YT1 A;  5HE2 A;  3SUZ A;  3PG7 A;  3FEH A;  3TVV A;  2MFQ A;  2D9Y A;  5J3Q A;  3F5R A;  1EAZ A;  3BJI A;  3D8E A;  3PEG A;  4HAX B;  1MIX A;  2KUP A;  2P8V A;  3NWA A;  2Y8F A;  2J0M A;  3SV1 A;  5GOW B;  4P7I A;  2DA0 A;  1I2H A;  3G9W A;  1SHC A;  1Z87 A;  1U5F A;  1DDW A;  5J3T A;  1X1G A;  1SGH A;  1FB8 A;  1U5E A;  3VIA A;  1U5D A;  4GOU A;  2RLO A;  2MDX A;  4GPT B;  2FJU B;  1EF1 A;  2CY5 A;  4K2O A;  3HK0 A;  1NTY A;  3PVW A;  4Z2M B;  1ZYI A;  1PMS A;  2H7E A;  2X18 A;  3ZVR A;  3ULC A;  1MI1 A;  2CRF A;  4Z2N A;  4ZRJ A;  1RJ2 A;  3TCA A;  1E5W A;  4F7U P;  2D9Z A;  1MPH A;  4HB0 B;  2GS0 A;  4HAV B;  2CAY A;  2DKQ A;  5D3V A;  4DIX A;  1LW3 A;  1ZVR A;  1BAK A;  2KGX B;  4K2P A;  3TO1 A;  1J0W A;  2K8E A;  3QIJ A;  5FI0 A;  3PSC A;  1OQN A;  3D8D A;  3RCP A;  3DXC A;  5JP4 A;  2K49 A;  4GMX B;  3X23 A;  1NI2 A;  4MY6 A;  2JP2 A;  4F7H A;  1LB1 A;  2I5F A;  4GNK B;  2DX1 A;  1UPQ A;  2KCJ A;  4IOY X;  3U8Z A;  2DYQ A;  2EC1 A;  2DTC A;  2RNR B;  1DYN A;  2P0H A;  1KZ7 A;  4A6H A;  3CXB B;  5DI9 B;  4DBB A;  1U5G A;  1TQZ A;  2K2J A;  3A8Q A;  2J0J A;  2FJL A;  4YON A;  3WA0 A;  4HAZ B;  3A98 B;  5CLQ B;  1Q67 A;  4L6E A;  2K00 A;  4HAT B;  2BCJ A;  4CHJ A;  1V88 A;  3FM8 C;  1ZM0 A;  2LOX A;  3UZT A;  1GC7 A;  3QBV B;  4HHV A;  2XQN M;  1K5D B;  3HW2 B;  4KVG B;  1X86 A;  2COD A;  1I7A A;  1GC6 A;  1KI1 B;  2CY4 A;  2GCL A;  1W1H A;  1UNP A;  5I2M A;  5HE3 A;  4PNK A;  4QJ4 B;  5KCV A;  2E2X A;  2DYN A;  2RRF A;  3SO6 A;  2N23 A;  1OY2 A;  4GN1 A;  3NWD A;  2KIG A;  1XOD A;  3F0W A;  3M1I B;  3QWM A;  3PP2 A;  1B55 A;  2KIE A;  1P5T A;  1W1G A;  2I5C A;  3GYP A;  3KSY A;  5DIF B;  2W2X C;  5D27 A;  2Y7B A;  2N0Y A;  3ODO A;  3T06 A;  1U29 A;  2IYB A;  2Z14 A;  1P3R A;  4KAX B;  2YS5 A;  1V5P A;  1MAI A;  2LOZ A;  1V5M A;  5C79 A;  1MKE A;  4GZU A;  5FI1 A;  4XWX A; 
#chains in the Genus database with same CATH homology
 4WSF A;  2Z0Q A;  3HQC A;  4F7G A;  5D3W A;  3KZ1 A;  2HTH B;  2OQB A;  2DN6 A;  4TKN A;  5D3X A;  2MWN B;  1WG7 A;  1TXD A;  4A6F A;  1FHO A;  4ZRI A;  4WJ7 A;  1WJM A;  2PZ1 A;  1QQG A;  2W2X D;  2Y8G A;  1KZG A;  3PVU A;  1M7R A;  5CLL B;  5J3Y A;  2LG1 A;  1Y5O A;  5DHF B;  4A6F B;  2RVB B;  2D4Q A;  2D11 A;  1XD4 A;  2DFK A;  1GG3 A;  2YSZ A;  5EFX A;  1FHW A;  4EKU A;  2J59 M;  2D9W A;  2R0D A;  3FSS A;  3KRW A;  2Z0P A;  2NZ8 B;  1WGU A;  5JHG A;  4A6K A;  1NTV A;  5C16 A;  4NSW A;  4B6H A;  2RGN B;  4HAU B;  3VOQ A;  1PFJ A;  1N3H A;  4IAP A;  4C0A A;  1J19 A;  1FOE A;  2IFS A;  3CIK A;  2I1K A;  2H7D A;  1MK9 B;  2ELB A;  1XCG A;  3O96 A;  4NY0 A;  1MIZ B;  2ZPY A;  2DHI A;  5JHH A;  5C5B A;  1DDV A;  4DX8 A;  2YRY A;  2EMS A;  3AU5 A;  1W1D A;  4K17 A;  1XKE A;  2AEH A;  1DDM A;  5HE1 A;  1K5G B;  3IVF A;  2QKM A;  2P0F A;  4Y94 A;  5C5B B;  1DRO A;  3LJU X;  1FAO A;  3AJ4 A;  4HDQ A;  4MK0 A;  2MKR A;  5KQ1 A;  2DHK A;  2ROV A;  2Q13 A;  2ROZ B;  4KHA A;  1RRP B;  1ZSQ A;  2Z0O A;  1U2B A;  1MK7 B;  2VRW B;  1Y19 B;  2GJY A;  5HE0 A;  3WYF B;  2ADZ A;  3OAN A;  1ZC4 B;  1M7E A;  4PQ0 A;  1UNR A;  4EMO A;  3A8P A;  3TW1 A;  2P0D A;  3ODW A;  2EJ8 A;  2YVC A;  1V5U A;  1OMW A;  1UNQ A;  1FGY A;  4HB2 B;  4HAY B;  3SYX A;  3P7Z A;  3DXD A;  1PLS A;  2V76 A;  1IRS A;  1TJ6 A;  3P6A A;  1XX0 A;  4KHB B;  4K81 A;  1BTN A;  2RUK B;  4WVF B;  5JLJ B;  1U27 A;  5L81 A;  2COC A;  2COF A;  3BIN A;  1V61 A;  4HDO A;  2HE7 A;  3KY9 A;  4ZRK A;  1XR0 B;  2ELA A;  4EJN A;  4IFS A;  2DLW A;  1X11 A;  4CYE A;  5LOP B;  2D10 A;  1BWN A;  3D8F A;  2W2W A;  4HB3 B;  5DH9 B;  3U7D A;  2RSG A;  1FGZ A;  1QC6 A;  1WVH A;  2M38 A;  2AL6 A;  2YS1 A;  3PZD A;  4GXB A;  1BTK A;  2YT0 A;  2LUL A;  2DKP A;  1AWE A;  4H8S A;  3GYO A;  2QKL A;  2G35 A;  5LON B;  3ML4 A;  2L2I A;  1WGQ A;  4A5K A;  2D9X A;  4DX9 0;  4D0N B;  2D2Q A;  2R09 A;  1WI1 A;  2UZS A;  1DBH A;  3N7C A;  2UZR A;  5KQ4 A;  2DX5 A;  1UPR A;  2NMB A;  2VKI A;  2YS3 A;  4BBK A;  1UEF A;  3MDB C;  4KHO A;  3DXE A;  1AQC A;  2K2U A;  3V5W A;  4HB4 B;  2YF0 A;  3ZDT A;  4CHM A;  3NSU A;  3TFM A;  5C6R A;  1NU2 A;  4DXA B;  4GMV A;  1H10 A;  1WJ1 A;  2L1C A;  5DHA B;  1EGX A;  2I1J A;  3AU4 A;  2GCJ A;  2OTX A;  2J0K A;  2UVM A;  3PVL A;  4TYZ A;  1V89 A;  2COA A;  2DHJ A;  2LYD A;  3SNH A;  3MPX A;  4YL8 A;  4MT7 A;  3KRX A;  2D9V A;  1ZC3 B;  3ULB A;  5D3Y A;  1H4R A;  1P6S A;  2LKO A;  1ISN A;  2EMT A;  1X05 A;  4HAW B;  2VSZ A;  1EVH A;  3ODX A;  2M14 A;  1FHX A;  1X1F A;  2YT1 A;  5HE2 A;  3SUZ A;  3PG7 A;  3FEH A;  3TVV A;  2MFQ A;  2D9Y A;  5J3Q A;  3F5R A;  1EAZ A;  3BJI A;  3D8E A;  3PEG A;  4HAX B;  1MIX A;  2KUP A;  2P8V A;  2Y8F A;  2J0M A;  3SV1 A;  5GOW B;  4P7I A;  2DA0 A;  1I2H A;  3G9W A;  1SHC A;  1Z87 A;  1U5F A;  1DDW A;  5J3T A;  1X1G A;  1SGH A;  1FB8 A;  1U5E A;  3VIA A;  1U5D A;  2RLO A;  2MDX A;  4GPT B;  1EF1 A;  2CY5 A;  4K2O A;  3HK0 A;  1NTY A;  3PVW A;  4Z2M B;  1PMS A;  2H7E A;  2X18 A;  3ZVR A;  3ULC A;  2CRF A;  4Z2N A;  4ZRJ A;  1RJ2 A;  3TCA A;  1E5W A;  4F7U P;  2D9Z A;  1MPH A;  4HB0 B;  2GS0 A;  4HAV B;  2CAY A;  2DKQ A;  5D3V A;  1LW3 A;  1ZVR A;  1BAK A;  2KGX B;  4K2P A;  3TO1 A;  1J0W A;  3QIJ A;  5FI0 A;  3PSC A;  1OQN A;  3D8D A;  3RCP A;  3DXC A;  5JP4 A;  4GMX B;  3X23 A;  1NI2 A;  4MY6 A;  2JP2 A;  4F7H A;  1LB1 A;  2I5F A;  2DX1 A;  1UPQ A;  2KCJ A;  4IOY X;  3U8Z A;  2DYQ A;  2EC1 A;  2DTC A;  2RNR B;  1DYN A;  2P0H A;  1KZ7 A;  4A6H A;  3CXB B;  5DI9 B;  4DBB A;  1U5G A;  1TQZ A;  2K2J A;  3A8Q A;  2J0J A;  2FJL A;  4YON A;  3WA0 A;  4HAZ B;  3A98 B;  5CLQ B;  1Q67 A;  4L6E A;  2K00 A;  4HAT B;  2BCJ A;  4CHJ A;  1V88 A;  3FM8 C;  1ZM0 A;  2LOX A;  3UZT A;  1GC7 A;  3QBV B;  4HHV A;  2XQN M;  1K5D B;  3HW2 B;  4KVG B;  1X86 A;  2COD A;  1I7A A;  1GC6 A;  1KI1 B;  2CY4 A;  2GCL A;  1W1H A;  1UNP A;  5HE3 A;  4PNK A;  5KCV A;  2E2X A;  2DYN A;  3SO6 A;  2N23 A;  1OY2 A;  4GN1 A;  3F0W A;  1XOD A;  3M1I B;  3QWM A;  3PP2 A;  1B55 A;  1P5T A;  1W1G A;  2I5C A;  3GYP A;  3KSY A;  5DIF B;  2W2X C;  5D27 A;  2Y7B A;  2N0Y A;  3ODO A;  3T06 A;  1U29 A;  2IYB A;  1P3R A;  4KAX B;  2YS5 A;  1V5P A;  1MAI A;  2LOZ A;  1V5M A;  5C79 A;  1MKE A;  4GZU A;  5FI1 A;  4XWX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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