4K2PA

The structure of a quintuple mutant of the tiam1 ph-cc-ex domain
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
238
structure length
238
Chain Sequence
b'TVRKAGALAVKNFLVHKKNKKVESATRRKWKHYWVSLKGCTLFFYESDGRSGIDHNSIPKHAVWVENSIVQAVPEHPKKDFVFCLSNSLGDAFLFQTTSQTELENWITAIHSACATAVARHHHKEDTLRLLKSEIKKLEQKIDMDEKLKKMGELQLSSVTDSKAAATILDQIFVWEQNLEQFQMDLFRFRCYLASLQGGELPNPKRLLAFASRPTKVAMGRLGIFSVSSFHALVAART'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords T-lymphoma invasion and metastasis-inducing protein 1
publication title High-resolution structure of the Tiam1 PHn-CC-Ex domain.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Signaling protein
total genus 78
structure length 238
sequence length 238
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-04-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF18385 Tiam_CC_Ex T-lymphoma invasion and metastasis CC-Ex domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 4k2pA01
2D11A 3P6AA 5EFXA 2H7DA 2Y8GA 3F0WA 1J0WA 1FOEA 1XR0B 2DKPA 1P5TA 1MKEA 2KCJA 4KHAA 1EAZA 1WI1A 5L81A 1UPQA 4B6HA 5DIFB 5JP4A 1AWEA 1QQGA 2DLWA 2EMTA 5JHHA 2R09A 5LOPB 5J3TA 1DBHA 2DX5A 3PVLA 2J0MA 3DXDA 1XKEA 1ZC4B 3PSCA 2Q13A 1H4RA 1E5WA 4GZUA 1IRSA 4WSFA 5D3WA 3PP2A 1OQNA 1U2BA 2L2IA 3QIJA 1GG3A 4A6KA 1Z87A 3SO6A 4HB3B 2I1JA 5KQ4A 1P6SA 2L1CA 1WVHA 2W2XD 2P0HA 2LKOA 2K2JA 2EJ8A 1KI1B 2I5CA 1EF1A 1ZSQA 4K2OA 4NY0A 1GC7A 1J19A 1EGXA 4K2PA 5D3XA 1X1GA 2AEHA 4YONA 2GS0A 2COFA 2J0JA 4HAUB 3KZ1A 2ZPYA 3U8ZA 1NU2A 1U5FA 2ROZB 4TYZA 4XWXA 2QKMA 2E2XA 2ADZA 4GPTB 3PVWA 2RNRB 3FM8C 2D9YA 3GYPA 5CLQB 2P0DA 4A6FA 1U5GA 4A5KA 4TKNA 1U5DA 2CODA 1ISNA 1DYNA 5DI9B 3ULCA 5C5BA 2H7EA 2MWNB 1N3HA 5HE3A 1BTKA 2MFQA 4K17A 3U7DA 2YF0A 2OQBA 5J3YA 2COAA 1OY2A 1W1HA 5J3QA 4F7HA 1V5PA 5FI0A 3SYXA 2M38A 2I5FA 3ODOA 2DYNA 2D9WA 1B55A 3ML4A 4HAXB 3WYFB 5HE1A 4GN1A 4WVFB 2YS3A 2R0DA 4CHMA 1KZGA 1AQCA 1WJMA 2LYDA 4IAPA 1NTVA 3P7ZA 4K81A 4NSWA 3HK0A 5HE2A 4HDOA 4F7GA 1U5EA 2DYQA 3WA0A 1FHXA 2OTXA 2LOXA 5DHAB 2CRFA 2V76A 2RGNB 2J59M 4Z2MB 2YSZA 2YT0A 4ZRIA 1DDWA 2Y8FA 4A6HA 2HTHB 4C0AA 4CHJA 4HDQA 1GC6A 2YT1A 3KRXA 4EJNA 1MAIA 1LB1A 1BAKA 4DX90 4GMXB 2CY5A 3A8PA 1NI2A 4EKUA 3BINA 3TCAA 4DX8A 3TFMA 3M1IB 3D8DA 2IFSA 1WJ1A 4MT7A 2AL6A 1DDVA 2J0KA 2W2XC 1Y5OA 2DKQA 1PMSA 2NZ8B 1EVHA 2P0FA 5LONB 2KUPA 3T06A 3BJIA 1LW3A 4KHOA 2GJYA 2Z0PA 2RVBB 2XQNM 4KAXB 3ODXA 2ELAA 1M7RA 3CIKA 4ZRJA 1UNPA 3HW2B 4HB2B 3X23A 3ZVRA 4PNKA 2X18A 2NMBA 4EMOA 3QBVB 4HHVA 1QC6A 1RJ2A 1W1GA 1DDMA 4ZRKA 2UZSA 2LULA 1P3RA 1MIZB 2GCLA 4WJ7A 1FAOA 3AU4A 1M7EA 2YS5A 1ZM0A 1Q67A 5C16A 2LOZA 3OANA 2K00A 3PEGA 4A6FB 2LG1A 3NSUA 4KHBB 2D10A 5C5BB 1TQZA 3SNHA 1BWNA 1NTYA 2DA0A 1V61A 4MY6A 1BTNA 2DTCA 2W2WA 1DROA 2Z0QA 5JLJB 1XD4A 4BBKA 5C79A 2RSGA 1ZC3B 5D27A 2N23A 4GXBA 3FSSA 3ODWA 1UPRA 3N7CA 1MPHA 1K5DB 1MK9B 4CYEA 2MDXA 3MDBC 4IFSA 3D8EA 1I7AA 2DFKA 1FB8A 3AJ4A 4IOYX 4H8SA 1SHCA 4Z2NA 2YS1A 4L6EA 5GOWB 1I2HA 1U29A 4Y94A 5C6RA 2K2UA 1PLSA 2UVMA 5DHFB 1XX0A 3A98B 1WGQA 5CLLB 4F7UP 4HAZB 5JHGA 1ZVRA 2D9XA 4GMVA 1TXDA 3TVVA 4MK0A 3PZDA 3QWMA 4DXAB 5FI1A 3RCPA 2VKIA 1MK7B 2D2QA 1FHOA 1SGHA 4DBBA 1FGYA 1KZ7A 2DHIA 4HAVB 1X1FA 2VSZA 5KQ1A 3DXCA 3CXBB 1MIXA 2VRWB 2Y7BA 5KCVA 1X11A 3O96A 1WGUA 1FHWA 2COCA 1PFJA 3G9WA 3TW1A 2CY4A 3PG7A 4HAYB 2RUKB 2EMSA 2GCJA 3PVUA 2P8VA 5DH9B 1UNQA 3LJUX 3ZDTA 2DHJA 2DX1A 2I1KA 2RLOA 3KY9A 2MKRA 2YVCA 3UZTA 1V88A 2N0YA 2YRYA 3SUZA 3ULBA 3KRWA 1V5MA 1XODA 3A8QA 3GYOA 2ROVA 3F5RA 3SV1A 1W1DA 1X86A 3V5WA 2DHKA 1RRPB 2UZRA 3KSYA 3AU5A 3VIAA 2IYBA 4D0NB 2JP2A 4HATB 5HE0A 2HE7A 3VOQA 2G35A 4KVGB 4PQ0A 3IVFA 3TO1A 1V89A 5D3YA 1TJ6A 3FEHA 2QKLA 2D9ZA 1Y19B 1K5GB 4HAWB 5D3VA 3HQCA 1FGZA 2D4QA 2EC1A 2FJLA 1UNRA 4YL8A 2KGXB 4HB0B 2BCJA 1UEFA 3D8FA 1OMWA 4HB4B 1H10A 2DN6A 1X05A 2D9VA 1U27A 2CAYA 1V5UA 3MPXA 2PZ1A 4P7IA 2ELBA 2Z0OA 3DXEA 1WG7A 2M14A 1XCGA
chains in the Genus database with same CATH superfamily
2D11A 3P6AA 5EFXA 2NBVA 2H7DA 2Y8GA 3F0WA 1J0WA 1FOEA 1XR0B 2DKPA 1P5TA 1MKEA 2KCJA 4KHAA 1EAZA 1WI1A 4OT1A 5L81A 1UPQA 4B6HA 5DIFB 5JP4A 1AWEA 1QQGA 2DLWA 2EMTA 5JHHA 2R09A 5LOPB 5J3TA 1DBHA 2DX5A 2FJUB 3PVLA 2J0MA 3DXDA 1XKEA 1ZC4B 4QJ4B 3PSCA 2Q13A 1H4RA 1E5WA 4GZUA 1IRSA 4WSFA 5D3WA 3PP2A 1OQNA 1U2BA 2L2IA 1T77A 3QIJA 1GG3A 4A6KA 5M4YB 1Z87A 3SO6A 2K49A 4HB3B 2I1JA 3NW8A 5KQ4A 1P6SA 2L1CA 1WVHA 2W2XD 2P0HA 2LKOA 2K2JA 2EJ8A 3NWDA 1KI1B 2I5CA 1EF1A 1ZSQA 4K2OA 4NY0A 1GC7A 1J19A 1EGXA 4K2PA 5D3XA 1X1GA 2AEHA 4GOUA 4YONA 2GS0A 5IRSA 2COFA 4HSIA 2J0JA 4HAUB 3KZ1A 2GUMA 2ZPYA 3U8ZA 1NU2A 1U5FA 2ROZB 4TYZA 4XWXA 2QKMA 2E2XA 2ADZA 4GPTB 3PVWA 2RNRB 3FM8C 2D9YA 4GNKB 3GYPA 5CLQB 2P0DA 4A6FA 1U5GA 4A5KA 4TKNA 1U5DA 2CODA 1ISNA 1DYNA 4KHBA 5DI9B 3ULCA 5C5BA 2H7EA 2MWNB 1N3HA 5HE3A 1BTKA 2MFQA 4K17A 3U7DA 2YF0A 2OQBA 5J3YA 2COAA 1OY2A 1W1HA 5J3QA 4F7HA 1V5PA 5FI0A 3SYXA 2M38A 2I5FA 2DYNA 2D9WA 3ODOA 1B55A 3ML4A 4HAXB 3WYFB 5HE1A 4GN1A 4WVFB 2YS3A 2R0DA 4CHMA 1KZGA 1AQCA 1WJMA 2LYDA 4IAPA 1NTVA 3P7ZA 4K81A 4NSWA 3HSAA 4L1RA 3HK0A 5HE2A 4HDOA 4F7GA 1U5EA 2DYQA 3WA0A 1FHXA 2OTXA 2LOXA 5DHAB 2CRFA 2V76A 2RGNB 2J59M 4Z2MB 2YSZA 2YT0A 4ZRIA 1DDWA 2Y8FA 4A6HA 2HTHB 4C0AA 4DIXA 4CHJA 4HDQA 1GC6A 2YT1A 3KRXA 5I2MA 4EJNA 1MAIA 3U12A 1LB1A 1BAKA 4DX90 4GMXB 2CY5A 3A8PA 1NI2A 3B77A 4EKUA 3BINA 3TCAA 4DX8A 3TFMA 3M1IB 3D8DA 2IFSA 1WJ1A 4MT7A 2Z13A 2AL6A 1DDVA 2J0KA 3OHMB 2W2XC 1Y5OA 2DKQA 1PMSA 2NZ8B 1EVHA 2P0FA 5LONB 2KUPA 3HIEA 3T06A 3BJIA 1LW3A 4KHOA 2GJYA 2Z0PA 5I2SA 2RVBB 2XQNM 4KAXB 3ODXA 2ELAA 1M7RA 3CIKA 4ZRJA 1UNPA 3HW2B 4HB2B 3X23A 3ZVRA 4PNKA 2X18A 2NMBA 4EMOA 3QBVB 4HHVA 1QC6A 1RJ2A 1W1GA 1DDMA 4ZRKA 4CSQA 2RRFA 2UZSA 2LULA 1P3RA 1MIZB 2GCLA 4WJ7A 1FAOA 3AU4A 1M7EA 2YS5A 1ZM0A 1Q67A 5C16A 2LOZA 1MI1A 2K00A 3OANA 3PEGA 4A6FB 2LG1A 3NSUA 4KHBB 2D10A 5C5BB 1TQZA 3SNHA 1BWNA 1NTYA 2DA0A 1V61A 4MY6A 1BTNA 2DTCA 2W2WA 1DROA 2Z0QA 5JLJB 1XD4A 4BBKA 5C79A 2RSGA 1ZC3B 5D27A 2N23A 4GXBA 3FSSA 4OSNA 3DCXA 3ODWA 1UPRA 4QJ5B 3N7CA 1MPHA 1K5DB 2YT2A 1MK9B 4CYEA 2MDXA 3MDBC 4IFSA 3D8EA 1I7AA 2DFKA 1ZYIA 1FB8A 2Z14A 3AJ4A 4IOYX 4H8SA 1SHCA 4Z2NA 2YS1A 4L6EA 5GOWB 1I2HA 1U29A 4Y94A 5C6RA 2K2UA 1PLSA 2UVMA 5DHFB 1XX0A 3A98B 1WGQA 5CLLB 4F7UP 4HAZB 5JHGA 1ZVRA 2ZKMX 2D9XA 4QJ3B 4GMVA 1TXDA 3TVVA 2K8EA 4MK0A 3PZDA 3QWMA 4DXAB 5FI1A 2KIGA 3RCPA 2VKIA 1MK7B 2D2QA 1FHOA 1SGHA 4DBBA 1FGYA 1KZ7A 2DHIA 4HAVB 1X1FA 2KUQA 5LG4B 2VSZA 5KQ1A 3DXCA 3CXBB 1MIXA 2VRWB 2Y7BA 5KCVA 1X11A 3O96A 1WGUA 1FHWA 2Z59A 2COCA 1PFJA 3A58A 2KIEA 3G9WA 3TW1A 2CY4A 3PG7A 4HAYB 2RUKB 2EMSA 4D6WA 2GCJA 3PVUA 2P8VA 5DH9B 1UNQA 3LJUX 3ZDTA 2DHJA 2DX1A 2I1KA 2RLOA 3KY9A 2MKRA 2YVCA 3UZTA 1V88A 2N0YA 2YRYA 3SUZA 3FVCA 3ULBA 3KRWA 1V5MA 1XODA 3A8QA 3GYOA 2ROVA 3F5RA 3SV1A 1W1DA 1X86A 3V5WA 2DHKA 1RRPB 2UZRA 3KSYA 3AU5A 3NWFA 3VIAA 2Z4DA 2IYBA 4D0NB 2JP2A 4HATB 5HE0A 2HE7A 3VOQA 2G35A 4KVGB 4PQ0A 3NWAA 3IVFA 3TO1A 1V89A 5D3YA 2KR0A 1TJ6A 3FEHA 2R2YA 2QKLA 2D9ZA 1Y19B 1K5GB 4HAWB 5D3VA 3HQCA 1FGZA 2D4QA 2EC1A 2FJLA 1UNRA 4YL8A 4QXAB 2KGXB 4HB0B 2BCJA 1UEFA 3D8FA 1OMWA 4HB4B 1H10A 2DN6A 1X05A 2D9VA 1U27A 2CAYA 1V5UA 3MPXA 2PZ1A 4P7IA 2ELBA 2Z0OA 3DXEA 1WG7A 2M14A 1XCGA
chains in the Genus database with same CATH topology
2D11A 3P6AA 5EFXA 2H7DA 2Y8GA 3F0WA 1J0WA 1FOEA 1XR0B 2DKPA 1P5TA 1MKEA 2KCJA 4KHAA 1EAZA 1WI1A 5L81A 1UPQA 4B6HA 5DIFB 5JP4A 1AWEA 1QQGA 2DLWA 2EMTA 5JHHA 2R09A 5LOPB 5J3TA 1DBHA 2DX5A 3PVLA 2J0MA 3DXDA 1XKEA 1ZC4B 3PSCA 2Q13A 1H4RA 1E5WA 4GZUA 1IRSA 4WSFA 5D3WA 3PP2A 1OQNA 1U2BA 2L2IA 3QIJA 1GG3A 4A6KA 1Z87A 3SO6A 4HB3B 2I1JA 5KQ4A 1P6SA 2L1CA 1WVHA 2W2XD 2P0HA 2LKOA 2K2JA 2EJ8A 1KI1B 2I5CA 1EF1A 1ZSQA 4K2OA 4NY0A 1GC7A 1J19A 1EGXA 4K2PA 5D3XA 1X1GA 2AEHA 4YONA 2GS0A 2COFA 2J0JA 4HAUB 3KZ1A 2ZPYA 3U8ZA 1NU2A 1U5FA 2ROZB 4TYZA 4XWXA 2QKMA 2E2XA 2ADZA 4GPTB 3PVWA 2RNRB 3FM8C 2D9YA 3GYPA 5CLQB 2P0DA 4A6FA 1U5GA 4A5KA 4TKNA 1U5DA 2CODA 1ISNA 1DYNA 5DI9B 3ULCA 5C5BA 2H7EA 2MWNB 1N3HA 5HE3A 1BTKA 2MFQA 4K17A 3U7DA 2YF0A 2OQBA 5J3YA 2COAA 1OY2A 1W1HA 5J3QA 4F7HA 1V5PA 5FI0A 3SYXA 2M38A 2I5FA 3ODOA 2DYNA 2D9WA 1B55A 3ML4A 4HAXB 3WYFB 5HE1A 4GN1A 4WVFB 2YS3A 2R0DA 4CHMA 1KZGA 1AQCA 1WJMA 2LYDA 4IAPA 1NTVA 3P7ZA 4K81A 4NSWA 3HK0A 5HE2A 4HDOA 4F7GA 1U5EA 2DYQA 3WA0A 1FHXA 2OTXA 2LOXA 5DHAB 2CRFA 2V76A 2RGNB 2J59M 4Z2MB 2YSZA 2YT0A 4ZRIA 1DDWA 2Y8FA 4A6HA 2HTHB 4C0AA 4CHJA 4HDQA 1GC6A 2YT1A 3KRXA 4EJNA 1MAIA 1LB1A 1BAKA 4DX90 4GMXB 2CY5A 3A8PA 1NI2A 4EKUA 3BINA 3TCAA 4DX8A 3TFMA 3M1IB 3D8DA 2IFSA 1WJ1A 4MT7A 2AL6A 1DDVA 2J0KA 2W2XC 1Y5OA 2DKQA 1PMSA 2NZ8B 1EVHA 2P0FA 5LONB 2KUPA 3T06A 3BJIA 1LW3A 4KHOA 2GJYA 2Z0PA 2RVBB 2XQNM 4KAXB 3ODXA 2ELAA 1M7RA 3CIKA 4ZRJA 1UNPA 3HW2B 4HB2B 3X23A 3ZVRA 4PNKA 2X18A 2NMBA 4EMOA 3QBVB 4HHVA 1QC6A 1RJ2A 1W1GA 1DDMA 4ZRKA 2UZSA 2LULA 1P3RA 1MIZB 2GCLA 4WJ7A 1FAOA 3AU4A 1M7EA 2YS5A 1ZM0A 1Q67A 5C16A 2LOZA 3OANA 2K00A 3PEGA 4A6FB 2LG1A 3NSUA 4KHBB 2D10A 5C5BB 1TQZA 3SNHA 1BWNA 1NTYA 2DA0A 1V61A 4MY6A 1BTNA 2DTCA 2W2WA 1DROA 2Z0QA 5JLJB 1XD4A 4BBKA 5C79A 2RSGA 1ZC3B 5D27A 2N23A 4GXBA 3FSSA 3ODWA 1UPRA 3N7CA 1MPHA 1K5DB 1MK9B 4CYEA 2MDXA 3MDBC 4IFSA 3D8EA 1I7AA 2DFKA 1FB8A 3AJ4A 4IOYX 4H8SA 1SHCA 4Z2NA 2YS1A 4L6EA 5GOWB 1I2HA 1U29A 4Y94A 5C6RA 2K2UA 1PLSA 2UVMA 5DHFB 1XX0A 3A98B 1WGQA 5CLLB 4F7UP 4HAZB 5JHGA 1ZVRA 2D9XA 4GMVA 1TXDA 3TVVA 4MK0A 3PZDA 3QWMA 4DXAB 5FI1A 3RCPA 2VKIA 1MK7B 2D2QA 1FHOA 1SGHA 4DBBA 1FGYA 1KZ7A 2DHIA 4HAVB 1X1FA 2VSZA 5KQ1A 3DXCA 3CXBB 1MIXA 2VRWB 2Y7BA 5KCVA 1X11A 3O96A 1WGUA 1FHWA 2COCA 1PFJA 3G9WA 3TW1A 2CY4A 3PG7A 4HAYB 2RUKB 2EMSA 2GCJA 3PVUA 2P8VA 5DH9B 1UNQA 3LJUX 3ZDTA 2DHJA 2DX1A 2I1KA 2RLOA 3KY9A 2MKRA 2YVCA 3UZTA 1V88A 2N0YA 2YRYA 3SUZA 3ULBA 3KRWA 1V5MA 1XODA 3A8QA 3GYOA 2ROVA 3F5RA 3SV1A 1W1DA 1X86A 3V5WA 2DHKA 1RRPB 2UZRA 3KSYA 3AU5A 3VIAA 2IYBA 4D0NB 2JP2A 4HATB 5HE0A 2HE7A 3VOQA 2G35A 4KVGB 4PQ0A 3IVFA 3TO1A 1V89A 5D3YA 1TJ6A 3FEHA 2QKLA 2D9ZA 1Y19B 1K5GB 4HAWB 5D3VA 3HQCA 1FGZA 2D4QA 2EC1A 2FJLA 1UNRA 4YL8A 2KGXB 4HB0B 2BCJA 1UEFA 3D8FA 1OMWA 4HB4B 1H10A 2DN6A 1X05A 2D9VA 1U27A 2CAYA 1V5UA 3MPXA 2PZ1A 4P7IA 2ELBA 2Z0OA 3DXEA 1WG7A 2M14A 1XCGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2D11 A;  3P6A A;  5EFX A;  2H7D A;  2Y8G A;  3F0W A;  1J0W A;  1FOE A;  1XR0 B;  2DKP A;  1P5T A;  1MKE A;  2KCJ A;  4KHA A;  1EAZ A;  1WI1 A;  5L81 A;  1UPQ A;  4B6H A;  5DIF B;  5JP4 A;  1AWE A;  1QQG A;  2DLW A;  2EMT A;  5JHH A;  2R09 A;  5LOP B;  5J3T A;  1DBH A;  2DX5 A;  3PVL A;  2J0M A;  3DXD A;  1XKE A;  1ZC4 B;  3PSC A;  2Q13 A;  1H4R A;  1E5W A;  4GZU A;  1IRS A;  4WSF A;  5D3W A;  3PP2 A;  1OQN A;  1U2B A;  2L2I A;  3QIJ A;  1GG3 A;  4A6K A;  1Z87 A;  3SO6 A;  4HB3 B;  2I1J A;  5KQ4 A;  1P6S A;  2L1C A;  1WVH A;  2W2X D;  2P0H A;  2LKO A;  2K2J A;  2EJ8 A;  1KI1 B;  2I5C A;  1EF1 A;  1ZSQ A;  4K2O A;  4NY0 A;  1GC7 A;  1J19 A;  1EGX A;  4K2P A;  5D3X A;  1X1G A;  2AEH A;  4YON A;  2GS0 A;  2COF A;  2J0J A;  4HAU B;  3KZ1 A;  2ZPY A;  3U8Z A;  1NU2 A;  1U5F A;  2ROZ B;  4TYZ A;  4XWX A;  2QKM A;  2E2X A;  2ADZ A;  4GPT B;  3PVW A;  2RNR B;  3FM8 C;  2D9Y A;  3GYP A;  5CLQ B;  2P0D A;  4A6F A;  1U5G A;  4A5K A;  4TKN A;  1U5D A;  2COD A;  1ISN A;  1DYN A;  5DI9 B;  3ULC A;  5C5B A;  2H7E A;  2MWN B;  1N3H A;  5HE3 A;  1BTK A;  2MFQ A;  4K17 A;  3U7D A;  2YF0 A;  2OQB A;  5J3Y A;  2COA A;  1OY2 A;  1W1H A;  5J3Q A;  4F7H A;  1V5P A;  5FI0 A;  3SYX A;  2M38 A;  2I5F A;  3ODO A;  2DYN A;  2D9W A;  1B55 A;  3ML4 A;  4HAX B;  3WYF B;  5HE1 A;  4GN1 A;  4WVF B;  2YS3 A;  2R0D A;  4CHM A;  1KZG A;  1AQC A;  1WJM A;  2LYD A;  4IAP A;  1NTV A;  3P7Z A;  4K81 A;  4NSW A;  3HK0 A;  5HE2 A;  4HDO A;  4F7G A;  1U5E A;  2DYQ A;  3WA0 A;  1FHX A;  2OTX A;  2LOX A;  5DHA B;  2CRF A;  2V76 A;  2RGN B;  2J59 M;  4Z2M B;  2YSZ A;  2YT0 A;  4ZRI A;  1DDW A;  2Y8F A;  4A6H A;  2HTH B;  4C0A A;  4CHJ A;  4HDQ A;  1GC6 A;  2YT1 A;  3KRX A;  4EJN A;  1MAI A;  1LB1 A;  1BAK A;  4DX9 0;  4GMX B;  2CY5 A;  3A8P A;  1NI2 A;  4EKU A;  3BIN A;  3TCA A;  4DX8 A;  3TFM A;  3M1I B;  3D8D A;  2IFS A;  1WJ1 A;  4MT7 A;  2AL6 A;  1DDV A;  2J0K A;  2W2X C;  1Y5O A;  2DKQ A;  1PMS A;  2NZ8 B;  1EVH A;  2P0F A;  5LON B;  2KUP A;  3T06 A;  3BJI A;  1LW3 A;  4KHO A;  2GJY A;  2Z0P A;  2RVB B;  2XQN M;  4KAX B;  3ODX A;  2ELA A;  1M7R A;  3CIK A;  4ZRJ A;  1UNP A;  3HW2 B;  4HB2 B;  3X23 A;  3ZVR A;  4PNK A;  2X18 A;  2NMB A;  4EMO A;  3QBV B;  4HHV A;  1QC6 A;  1RJ2 A;  1W1G A;  1DDM A;  4ZRK A;  2UZS A;  2LUL A;  1P3R A;  1MIZ B;  2GCL A;  4WJ7 A;  1FAO A;  3AU4 A;  1M7E A;  2YS5 A;  1ZM0 A;  1Q67 A;  5C16 A;  2LOZ A;  3OAN A;  2K00 A;  3PEG A;  4A6F B;  2LG1 A;  3NSU A;  4KHB B;  2D10 A;  5C5B B;  1TQZ A;  3SNH A;  1BWN A;  1NTY A;  2DA0 A;  1V61 A;  4MY6 A;  1BTN A;  2DTC A;  2W2W A;  1DRO A;  2Z0Q A;  5JLJ B;  1XD4 A;  4BBK A;  5C79 A;  2RSG A;  1ZC3 B;  5D27 A;  2N23 A;  4GXB A;  3FSS A;  3ODW A;  1UPR A;  3N7C A;  1MPH A;  1K5D B;  1MK9 B;  4CYE A;  2MDX A;  3MDB C;  4IFS A;  3D8E A;  1I7A A;  2DFK A;  1FB8 A;  3AJ4 A;  4IOY X;  4H8S A;  1SHC A;  4Z2N A;  2YS1 A;  4L6E A;  5GOW B;  1I2H A;  1U29 A;  4Y94 A;  5C6R A;  2K2U A;  1PLS A;  2UVM A;  5DHF B;  1XX0 A;  3A98 B;  1WGQ A;  5CLL B;  4F7U P;  4HAZ B;  5JHG A;  1ZVR A;  2D9X A;  4GMV A;  1TXD A;  3TVV A;  4MK0 A;  3PZD A;  3QWM A;  4DXA B;  5FI1 A;  3RCP A;  2VKI A;  1MK7 B;  2D2Q A;  1FHO A;  1SGH A;  4DBB A;  1FGY A;  1KZ7 A;  2DHI A;  4HAV B;  1X1F A;  2VSZ A;  5KQ1 A;  3DXC A;  3CXB B;  1MIX A;  2VRW B;  2Y7B A;  5KCV A;  1X11 A;  3O96 A;  1WGU A;  1FHW A;  2COC A;  1PFJ A;  3G9W A;  3TW1 A;  2CY4 A;  3PG7 A;  4HAY B;  2RUK B;  2EMS A;  2GCJ A;  3PVU A;  2P8V A;  5DH9 B;  1UNQ A;  3LJU X;  3ZDT A;  2DHJ A;  2DX1 A;  2I1K A;  2RLO A;  3KY9 A;  2MKR A;  2YVC A;  3UZT A;  1V88 A;  2N0Y A;  2YRY A;  3SUZ A;  3ULB A;  3KRW A;  1V5M A;  1XOD A;  3A8Q A;  3GYO A;  2ROV A;  3F5R A;  3SV1 A;  1W1D A;  1X86 A;  3V5W A;  2DHK A;  1RRP B;  2UZR A;  3KSY A;  3AU5 A;  3VIA A;  2IYB A;  4D0N B;  2JP2 A;  4HAT B;  5HE0 A;  2HE7 A;  3VOQ A;  2G35 A;  4KVG B;  4PQ0 A;  3IVF A;  3TO1 A;  1V89 A;  5D3Y A;  1TJ6 A;  3FEH A;  2QKL A;  2D9Z A;  1Y19 B;  1K5G B;  4HAW B;  5D3V A;  3HQC A;  1FGZ A;  2D4Q A;  2EC1 A;  2FJL A;  1UNR A;  4YL8 A;  2KGX B;  4HB0 B;  2BCJ A;  1UEF A;  3D8F A;  1OMW A;  4HB4 B;  1H10 A;  2DN6 A;  1X05 A;  2D9V A;  1U27 A;  2CAY A;  1V5U A;  3MPX A;  2PZ1 A;  4P7I A;  2ELB A;  2Z0O A;  3DXE A;  1WG7 A;  2M14 A;  1XCG A; 
#chains in the Genus database with same CATH topology
 2D11 A;  3P6A A;  5EFX A;  2NBV A;  2H7D A;  2Y8G A;  3F0W A;  1J0W A;  1FOE A;  1XR0 B;  2DKP A;  1P5T A;  1MKE A;  2KCJ A;  4KHA A;  1EAZ A;  1WI1 A;  4OT1 A;  5L81 A;  1UPQ A;  4B6H A;  5DIF B;  5JP4 A;  1AWE A;  1QQG A;  2DLW A;  2EMT A;  5JHH A;  2R09 A;  5LOP B;  5J3T A;  1DBH A;  2DX5 A;  2FJU B;  3PVL A;  2J0M A;  3DXD A;  1XKE A;  1ZC4 B;  4QJ4 B;  3PSC A;  2Q13 A;  1H4R A;  1E5W A;  4GZU A;  1IRS A;  4WSF A;  5D3W A;  3PP2 A;  1OQN A;  1U2B A;  2L2I A;  1T77 A;  3QIJ A;  1GG3 A;  4A6K A;  5M4Y B;  1Z87 A;  3SO6 A;  2K49 A;  4HB3 B;  2I1J A;  3NW8 A;  5KQ4 A;  1P6S A;  2L1C A;  1WVH A;  2W2X D;  2P0H A;  2LKO A;  2K2J A;  2EJ8 A;  3NWD A;  1KI1 B;  2I5C A;  1EF1 A;  1ZSQ A;  4K2O A;  4NY0 A;  1GC7 A;  1J19 A;  1EGX A;  4K2P A;  5D3X A;  1X1G A;  2AEH A;  4GOU A;  4YON A;  2GS0 A;  5IRS A;  2COF A;  4HSI A;  2J0J A;  4HAU B;  3KZ1 A;  2GUM A;  2ZPY A;  3U8Z A;  1NU2 A;  1U5F A;  2ROZ B;  4TYZ A;  4XWX A;  2QKM A;  2E2X A;  2ADZ A;  4GPT B;  3PVW A;  2RNR B;  3FM8 C;  2D9Y A;  4GNK B;  3GYP A;  5CLQ B;  2P0D A;  4A6F A;  1U5G A;  4A5K A;  4TKN A;  1U5D A;  2COD A;  1ISN A;  1DYN A;  4KHB A;  5DI9 B;  3ULC A;  5C5B A;  2H7E A;  2MWN B;  1N3H A;  5HE3 A;  1BTK A;  2MFQ A;  4K17 A;  3U7D A;  2YF0 A;  2OQB A;  5J3Y A;  2COA A;  1OY2 A;  1W1H A;  5J3Q A;  4F7H A;  1V5P A;  5FI0 A;  3SYX A;  2M38 A;  2I5F A;  2DYN A;  2D9W A;  3ODO A;  1B55 A;  3ML4 A;  4HAX B;  3WYF B;  5HE1 A;  4GN1 A;  4WVF B;  2YS3 A;  2R0D A;  4CHM A;  1KZG A;  1AQC A;  1WJM A;  2LYD A;  4IAP A;  1NTV A;  3P7Z A;  4K81 A;  4NSW A;  3HSA A;  4L1R A;  3HK0 A;  5HE2 A;  4HDO A;  4F7G A;  1U5E A;  2DYQ A;  3WA0 A;  1FHX A;  2OTX A;  2LOX A;  5DHA B;  2CRF A;  2V76 A;  2RGN B;  2J59 M;  4Z2M B;  2YSZ A;  2YT0 A;  4ZRI A;  1DDW A;  2Y8F A;  4A6H A;  2HTH B;  4C0A A;  4DIX A;  4CHJ A;  4HDQ A;  1GC6 A;  2YT1 A;  3KRX A;  5I2M A;  4EJN A;  1MAI A;  3U12 A;  1LB1 A;  1BAK A;  4DX9 0;  4GMX B;  2CY5 A;  3A8P A;  1NI2 A;  3B77 A;  4EKU A;  3BIN A;  3TCA A;  4DX8 A;  3TFM A;  3M1I B;  3D8D A;  2IFS A;  1WJ1 A;  4MT7 A;  2Z13 A;  2AL6 A;  1DDV A;  2J0K A;  3OHM B;  2W2X C;  1Y5O A;  2DKQ A;  1PMS A;  2NZ8 B;  1EVH A;  2P0F A;  5LON B;  2KUP A;  3HIE A;  3T06 A;  3BJI A;  1LW3 A;  4KHO A;  2GJY A;  2Z0P A;  5I2S A;  2RVB B;  2XQN M;  4KAX B;  3ODX A;  2ELA A;  1M7R A;  3CIK A;  4ZRJ A;  1UNP A;  3HW2 B;  4HB2 B;  3X23 A;  3ZVR A;  4PNK A;  2X18 A;  2NMB A;  4EMO A;  3QBV B;  4HHV A;  1QC6 A;  1RJ2 A;  1W1G A;  1DDM A;  4ZRK A;  4CSQ A;  2RRF A;  2UZS A;  2LUL A;  1P3R A;  1MIZ B;  2GCL A;  4WJ7 A;  1FAO A;  3AU4 A;  1M7E A;  2YS5 A;  1ZM0 A;  1Q67 A;  5C16 A;  2LOZ A;  1MI1 A;  2K00 A;  3OAN A;  3PEG A;  4A6F B;  2LG1 A;  3NSU A;  4KHB B;  2D10 A;  5C5B B;  1TQZ A;  3SNH A;  1BWN A;  1NTY A;  2DA0 A;  1V61 A;  4MY6 A;  1BTN A;  2DTC A;  2W2W A;  1DRO A;  2Z0Q A;  5JLJ B;  1XD4 A;  4BBK A;  5C79 A;  2RSG A;  1ZC3 B;  5D27 A;  2N23 A;  4GXB A;  3FSS A;  4OSN A;  3DCX A;  3ODW A;  1UPR A;  4QJ5 B;  3N7C A;  1MPH A;  1K5D B;  2YT2 A;  1MK9 B;  4CYE A;  2MDX A;  3MDB C;  4IFS A;  3D8E A;  1I7A A;  2DFK A;  1ZYI A;  1FB8 A;  2Z14 A;  3AJ4 A;  4IOY X;  4H8S A;  1SHC A;  4Z2N A;  2YS1 A;  4L6E A;  5GOW B;  1I2H A;  1U29 A;  4Y94 A;  5C6R A;  2K2U A;  1PLS A;  2UVM A;  5DHF B;  1XX0 A;  3A98 B;  1WGQ A;  5CLL B;  4F7U P;  4HAZ B;  5JHG A;  1ZVR A;  2ZKM X;  2D9X A;  4QJ3 B;  4GMV A;  1TXD A;  3TVV A;  2K8E A;  4MK0 A;  3PZD A;  3QWM A;  4DXA B;  5FI1 A;  2KIG A;  3RCP A;  2VKI A;  1MK7 B;  2D2Q A;  1FHO A;  1SGH A;  4DBB A;  1FGY A;  1KZ7 A;  2DHI A;  4HAV B;  1X1F A;  2KUQ A;  5LG4 B;  2VSZ A;  5KQ1 A;  3DXC A;  3CXB B;  1MIX A;  2VRW B;  2Y7B A;  5KCV A;  1X11 A;  3O96 A;  1WGU A;  1FHW A;  2Z59 A;  2COC A;  1PFJ A;  3A58 A;  2KIE A;  3G9W A;  3TW1 A;  2CY4 A;  3PG7 A;  4HAY B;  2RUK B;  2EMS A;  4D6W A;  2GCJ A;  3PVU A;  2P8V A;  5DH9 B;  1UNQ A;  3LJU X;  3ZDT A;  2DHJ A;  2DX1 A;  2I1K A;  2RLO A;  3KY9 A;  2MKR A;  2YVC A;  3UZT A;  1V88 A;  2N0Y A;  2YRY A;  3SUZ A;  3FVC A;  3ULB A;  3KRW A;  1V5M A;  1XOD A;  3A8Q A;  3GYO A;  2ROV A;  3F5R A;  3SV1 A;  1W1D A;  1X86 A;  3V5W A;  2DHK A;  1RRP B;  2UZR A;  3KSY A;  3AU5 A;  3NWF A;  3VIA A;  2Z4D A;  2IYB A;  4D0N B;  2JP2 A;  4HAT B;  5HE0 A;  2HE7 A;  3VOQ A;  2G35 A;  4KVG B;  4PQ0 A;  3NWA A;  3IVF A;  3TO1 A;  1V89 A;  5D3Y A;  2KR0 A;  1TJ6 A;  3FEH A;  2R2Y A;  2QKL A;  2D9Z A;  1Y19 B;  1K5G B;  4HAW B;  5D3V A;  3HQC A;  1FGZ A;  2D4Q A;  2EC1 A;  2FJL A;  1UNR A;  4YL8 A;  4QXA B;  2KGX B;  4HB0 B;  2BCJ A;  1UEF A;  3D8F A;  1OMW A;  4HB4 B;  1H10 A;  2DN6 A;  1X05 A;  2D9V A;  1U27 A;  2CAY A;  1V5U A;  3MPX A;  2PZ1 A;  4P7I A;  2ELB A;  2Z0O A;  3DXE A;  1WG7 A;  2M14 A;  1XCG A; 
#chains in the Genus database with same CATH homology
 2D11 A;  3P6A A;  5EFX A;  2H7D A;  2Y8G A;  3F0W A;  1J0W A;  1FOE A;  1XR0 B;  2DKP A;  1P5T A;  1MKE A;  2KCJ A;  4KHA A;  1EAZ A;  1WI1 A;  5L81 A;  1UPQ A;  4B6H A;  5DIF B;  5JP4 A;  1AWE A;  1QQG A;  2DLW A;  2EMT A;  5JHH A;  2R09 A;  5LOP B;  5J3T A;  1DBH A;  2DX5 A;  3PVL A;  2J0M A;  3DXD A;  1XKE A;  1ZC4 B;  3PSC A;  2Q13 A;  1H4R A;  1E5W A;  4GZU A;  1IRS A;  4WSF A;  5D3W A;  3PP2 A;  1OQN A;  1U2B A;  2L2I A;  3QIJ A;  1GG3 A;  4A6K A;  1Z87 A;  3SO6 A;  4HB3 B;  2I1J A;  5KQ4 A;  1P6S A;  2L1C A;  1WVH A;  2W2X D;  2P0H A;  2LKO A;  2K2J A;  2EJ8 A;  1KI1 B;  2I5C A;  1EF1 A;  1ZSQ A;  4K2O A;  4NY0 A;  1GC7 A;  1J19 A;  1EGX A;  4K2P A;  5D3X A;  1X1G A;  2AEH A;  4YON A;  2GS0 A;  2COF A;  2J0J A;  4HAU B;  3KZ1 A;  2ZPY A;  3U8Z A;  1NU2 A;  1U5F A;  2ROZ B;  4TYZ A;  4XWX A;  2QKM A;  2E2X A;  2ADZ A;  4GPT B;  3PVW A;  2RNR B;  3FM8 C;  2D9Y A;  3GYP A;  5CLQ B;  2P0D A;  4A6F A;  1U5G A;  4A5K A;  4TKN A;  1U5D A;  2COD A;  1ISN A;  1DYN A;  5DI9 B;  3ULC A;  5C5B A;  2H7E A;  2MWN B;  1N3H A;  5HE3 A;  1BTK A;  2MFQ A;  4K17 A;  3U7D A;  2YF0 A;  2OQB A;  5J3Y A;  2COA A;  1OY2 A;  1W1H A;  5J3Q A;  4F7H A;  1V5P A;  5FI0 A;  3SYX A;  2M38 A;  2I5F A;  3ODO A;  2DYN A;  2D9W A;  1B55 A;  3ML4 A;  4HAX B;  3WYF B;  5HE1 A;  4GN1 A;  4WVF B;  2YS3 A;  2R0D A;  4CHM A;  1KZG A;  1AQC A;  1WJM A;  2LYD A;  4IAP A;  1NTV A;  3P7Z A;  4K81 A;  4NSW A;  3HK0 A;  5HE2 A;  4HDO A;  4F7G A;  1U5E A;  2DYQ A;  3WA0 A;  1FHX A;  2OTX A;  2LOX A;  5DHA B;  2CRF A;  2V76 A;  2RGN B;  2J59 M;  4Z2M B;  2YSZ A;  2YT0 A;  4ZRI A;  1DDW A;  2Y8F A;  4A6H A;  2HTH B;  4C0A A;  4CHJ A;  4HDQ A;  1GC6 A;  2YT1 A;  3KRX A;  4EJN A;  1MAI A;  1LB1 A;  1BAK A;  4DX9 0;  4GMX B;  2CY5 A;  3A8P A;  1NI2 A;  4EKU A;  3BIN A;  3TCA A;  4DX8 A;  3TFM A;  3M1I B;  3D8D A;  2IFS A;  1WJ1 A;  4MT7 A;  2AL6 A;  1DDV A;  2J0K A;  2W2X C;  1Y5O A;  2DKQ A;  1PMS A;  2NZ8 B;  1EVH A;  2P0F A;  5LON B;  2KUP A;  3T06 A;  3BJI A;  1LW3 A;  4KHO A;  2GJY A;  2Z0P A;  2RVB B;  2XQN M;  4KAX B;  3ODX A;  2ELA A;  1M7R A;  3CIK A;  4ZRJ A;  1UNP A;  3HW2 B;  4HB2 B;  3X23 A;  3ZVR A;  4PNK A;  2X18 A;  2NMB A;  4EMO A;  3QBV B;  4HHV A;  1QC6 A;  1RJ2 A;  1W1G A;  1DDM A;  4ZRK A;  2UZS A;  2LUL A;  1P3R A;  1MIZ B;  2GCL A;  4WJ7 A;  1FAO A;  3AU4 A;  1M7E A;  2YS5 A;  1ZM0 A;  1Q67 A;  5C16 A;  2LOZ A;  3OAN A;  2K00 A;  3PEG A;  4A6F B;  2LG1 A;  3NSU A;  4KHB B;  2D10 A;  5C5B B;  1TQZ A;  3SNH A;  1BWN A;  1NTY A;  2DA0 A;  1V61 A;  4MY6 A;  1BTN A;  2DTC A;  2W2W A;  1DRO A;  2Z0Q A;  5JLJ B;  1XD4 A;  4BBK A;  5C79 A;  2RSG A;  1ZC3 B;  5D27 A;  2N23 A;  4GXB A;  3FSS A;  3ODW A;  1UPR A;  3N7C A;  1MPH A;  1K5D B;  1MK9 B;  4CYE A;  2MDX A;  3MDB C;  4IFS A;  3D8E A;  1I7A A;  2DFK A;  1FB8 A;  3AJ4 A;  4IOY X;  4H8S A;  1SHC A;  4Z2N A;  2YS1 A;  4L6E A;  5GOW B;  1I2H A;  1U29 A;  4Y94 A;  5C6R A;  2K2U A;  1PLS A;  2UVM A;  5DHF B;  1XX0 A;  3A98 B;  1WGQ A;  5CLL B;  4F7U P;  4HAZ B;  5JHG A;  1ZVR A;  2D9X A;  4GMV A;  1TXD A;  3TVV A;  4MK0 A;  3PZD A;  3QWM A;  4DXA B;  5FI1 A;  3RCP A;  2VKI A;  1MK7 B;  2D2Q A;  1FHO A;  1SGH A;  4DBB A;  1FGY A;  1KZ7 A;  2DHI A;  4HAV B;  1X1F A;  2VSZ A;  5KQ1 A;  3DXC A;  3CXB B;  1MIX A;  2VRW B;  2Y7B A;  5KCV A;  1X11 A;  3O96 A;  1WGU A;  1FHW A;  2COC A;  1PFJ A;  3G9W A;  3TW1 A;  2CY4 A;  3PG7 A;  4HAY B;  2RUK B;  2EMS A;  2GCJ A;  3PVU A;  2P8V A;  5DH9 B;  1UNQ A;  3LJU X;  3ZDT A;  2DHJ A;  2DX1 A;  2I1K A;  2RLO A;  3KY9 A;  2MKR A;  2YVC A;  3UZT A;  1V88 A;  2N0Y A;  2YRY A;  3SUZ A;  3ULB A;  3KRW A;  1V5M A;  1XOD A;  3A8Q A;  3GYO A;  2ROV A;  3F5R A;  3SV1 A;  1W1D A;  1X86 A;  3V5W A;  2DHK A;  1RRP B;  2UZR A;  3KSY A;  3AU5 A;  3VIA A;  2IYB A;  4D0N B;  2JP2 A;  4HAT B;  5HE0 A;  2HE7 A;  3VOQ A;  2G35 A;  4KVG B;  4PQ0 A;  3IVF A;  3TO1 A;  1V89 A;  5D3Y A;  1TJ6 A;  3FEH A;  2QKL A;  2D9Z A;  1Y19 B;  1K5G B;  4HAW B;  5D3V A;  3HQC A;  1FGZ A;  2D4Q A;  2EC1 A;  2FJL A;  1UNR A;  4YL8 A;  2KGX B;  4HB0 B;  2BCJ A;  1UEF A;  3D8F A;  1OMW A;  4HB4 B;  1H10 A;  2DN6 A;  1X05 A;  2D9V A;  1U27 A;  2CAY A;  1V5U A;  3MPX A;  2PZ1 A;  4P7I A;  2ELB A;  2Z0O A;  3DXE A;  1WG7 A;  2M14 A;  1XCG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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