1BWNA

Ph domain and btk motif from bruton's tyrosine kinase mutant e41k in complex with ins(1,3,4,5)p4
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
169
structure length
166
Chain Sequence
AAVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYKYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIPRRGSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILEN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords BRUTON'S TYROSINE KINASE
total genus 36
structure length 166
sequence length 169
chains with identical sequence B
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 1998-09-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF00779 BTK BTK motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1bwnA00
2CY4A 1V88A 4C0AA 1XD4A 3U8ZA 1M7RA 2Y7BA 4CHMA 2I5CA 5C16A 5HE2A 3P6AA 4HB0B 1DYNA 1QC6A 4Z2NA 1K5DB 5D27A 2RGNB 2HTHB 2CAYA 1UNQA 1FOEA 2E2XA 5KCVA 2FJLA 5LOPB 4GN1A 1KZGA 3HW2B 2YT0A 2I5FA 2GJYA 4F7HA 2HE7A 2LG1A 1X1GA 1U5DA 3VOQA 1XR0B 4DX8A 2DYQA 3A98B 1UNPA 3DXDA 5KQ1A 5LONB 2MWNB 2GCLA 3A8PA 1MKEA 4D0NB 1U5FA 2N0YA 2DHJA 2Z0OA 2UZRA 2UZSA 2X18A 1Z87A 3FSSA 3M1IB 4H8SA 1W1DA 2UVMA 1V5MA 2EJ8A 1UPQA 2J0MA 2DLWA 1ZC4B 3IVFA 2EMTA 4EMOA 4TYZA 4DBBA 2YF0A 3AU5A 2MDXA 2KGXB 3QIJA 1GC6A 2DKPA 2YS5A 2ROVA 4CYEA 1P6SA 3A8QA 5C5BB 1Y5OA 1M7EA 2DX1A 1H4RA 4F7GA 1RJ2A 2YS3A 2IFSA 2P0FA 3HK0A 1BTNA 2CRFA 5JP4A 4KAXB 1NTVA 2AL6A 4K17A 2M38A 2W2XC 4BBKA 2QKMA 4Y94A 4GMVA 4IFSA 5D3VA 3ZDTA 1UEFA 4A5KA 1Q67A 4GMXB 2H7DA 4MY6A 1X1FA 2RNRB 4HAUB 2YRYA 5JHHA 3PZDA 5JHGA 1AQCA 3QWMA 3TO1A 2DN6A 3ODOA 4HAVB 3ULBA 2LOZA 3DXCA 3P7ZA 1RRPB 3X23A 4GZUA 4HB4B 5D3XA 2D4QA 3PVUA 1BTKA 3SNHA 1I7AA 2RUKB 1P3RA 2R09A 2JP2A 2VRWB 3FEHA 1LB1A 4NY0A 1KI1B 3ODXA 3MPXA 4HHVA 1KZ7A 2KUPA 2GS0A 1FGZA 1TQZA 2DHIA 1Y19B 3TFMA 2BCJA 3WA0A 5C5BA 2L2IA 2EMSA 2D11A 2K2JA 2ROZB 1B55A 1OQNA 1EGXA 2YSZA 1WGUA 5DH9B 4DX90 1FHWA 4WVFB 1EF1A 1DDMA 3BJIA 3RCPA 4KHOA 1FGYA 2W2XD 4XWXA 2LOXA 1WI1A 1TJ6A 2Z0PA 2DX5A 3CIKA 4HDOA 2LYDA 5DIFB 2I1KA 4GPTB 2K2UA 2K00A 1LW3A 3SV1A 2J0KA 2XQNM 2W2WA 1NU2A 2VKIA 1XKEA 5C6RA 2DHKA 5KQ4A 1DDWA 4K81A 4A6KA 4ZRIA 3N7CA 1MAIA 3AJ4A 4ZRKA 2L1CA 5CLLB 4Z2MB 3ZVRA 1H10A 1XODA 5FI1A 2ZPYA 4PNKA 1DDVA 1V61A 4CHJA 2NZ8B 1WGQA 3ML4A 1U29A 2R0DA 3SO6A 5C79A 1UPRA 3BINA 3FM8C 2N23A 2P0HA 2OTXA 1MIZB 5J3QA 5HE1A 3DXEA 2D9XA 1OMWA 3TVVA 1QQGA 4YONA 1NTYA 1WJMA 2D9YA 4EJNA 1MK9B 5JLJB 1NI2A 2J0JA 2LULA 1WG7A 2CY5A 4YL8A 2YT1A 1IRSA 1MK7B 3F5RA 2Q13A 3D8EA 1U27A 3GYPA 1U5GA 1X86A 4K2PA 2COFA 3SYXA 4K2OA 2D9VA 1MPHA 2J59M 4IOYX 1ZVRA 3D8DA 4HAYB 4WJ7A 4WSFA 1PFJA 3UZTA 2ADZA 2I1JA 1P5TA 4KVGB 4P7IA 1W1GA 4TKNA 3TW1A 2COAA 5CLQB 2YVCA 4B6HA 1FB8A 2IYBA 2D9ZA 4HB3B 2KCJA 1W1HA 3T06A 1V5PA 3KSYA 3KRXA 3HQCA 3VIAA 4MK0A 5HE3A 2Y8FA 1ISNA 3LJUX 1XCGA 1SHCA 1AWEA 3F0WA 4HDQA 3GYOA 3WYFB 1U2BA 1X05A 2COCA 3G9WA 4GXBA 2DKQA 1FHXA 1WVHA 3O96A 5L81A 1PMSA 3ULCA 1U5EA 3PP2A 5J3TA 4EKUA 2G35A 1EAZA 1UNRA 1N3HA 4L6EA 2OQBA 2Z0QA 2DFKA 5J3YA 4A6HA 3MDBC 3KZ1A 3U7DA 3AU4A 1TXDA 2Y8GA 1PLSA 1X11A 1ZC3B 2RVBB 2LKOA 3QBVB 4IAPA 2RSGA 4KHBB 1OY2A 2D2QA 2RLOA 2MFQA 3PVWA 1E5WA 4HB2B 5DI9B 2CODA 5DHAB 1ZSQA 2ELBA 1BAKA 2MKRA 2D10A 1J19A 2H7EA 2EC1A 3TCAA 1K5GB 5EFXA 1J0WA 2QKLA 3KRWA 1FAOA 1DROA 2GCJA 1EVHA 3ODWA 3PVLA 2VSZA 4ZRJA 2NMBA 3KY9A 4A6FA 2DTCA 2PZ1A 4HATB 2V76A 2P0DA 1FHOA 4MT7A 5DHFB 4NSWA 1SGHA 3D8FA 2AEHA 3PG7A 5FI0A 3V5WA 1DBHA 1WJ1A 3SUZA 1XX0A 1V89A 4PQ0A 4HAWB 1GC7A 1GG3A 4HAXB 2M14A 4DXAB 5D3WA 1BWNA 3CXBB 2P8VA 2DA0A 5HE0A 1MIXA 3OANA 4HAZB 3NSUA 5D3YA 2DYNA 3PSCA 4KHAA 2YS1A 4F7UP 1ZM0A 3PEGA 5GOWB 2D9WA 2ELAA 1V5UA 1I2HA 4A6FB
chains in the Genus database with same CATH superfamily
2CY4A 1V88A 4C0AA 1XD4A 3U8ZA 1M7RA 2Y7BA 4CHMA 2I5CA 5C16A 5HE2A 3P6AA 4HB0B 1DYNA 1QC6A 4Z2NA 1K5DB 3NWDA 3NW8A 5D27A 2RGNB 2HTHB 2CAYA 1UNQA 1FOEA 2E2XA 5KCVA 2FJLA 5LOPB 4GN1A 1KZGA 3HW2B 2YT0A 2I5FA 2GJYA 4F7HA 4OSNA 2HE7A 2LG1A 1X1GA 1U5DA 3VOQA 1XR0B 4DX8A 2DYQA 3A98B 1UNPA 3DXDA 5KQ1A 5LONB 2MWNB 2GCLA 3A8PA 1MKEA 4D0NB 1U5FA 2N0YA 2DHJA 2Z0OA 2UZRA 2UZSA 2X18A 1Z87A 3FSSA 3M1IB 4H8SA 1W1DA 2UVMA 1V5MA 2EJ8A 1UPQA 2J0MA 2DLWA 1ZC4B 3IVFA 2EMTA 4EMOA 4TYZA 1MI1A 4DBBA 2YF0A 3AU5A 2MDXA 2KGXB 3QIJA 1GC6A 2YT2A 2DKPA 2YS5A 2ROVA 4CYEA 1P6SA 3A8QA 5C5BB 1Y5OA 1M7EA 2DX1A 1H4RA 4F7GA 1RJ2A 2YS3A 2IFSA 2P0FA 3HK0A 4QJ5B 1BTNA 2CRFA 5JP4A 2Z13A 4KAXB 2Z14A 1NTVA 2AL6A 4K17A 2M38A 2W2XC 4BBKA 2QKMA 4Y94A 2GUMA 4GMVA 4IFSA 5D3VA 3ZDTA 4GNKB 1UEFA 4A5KA 1Q67A 4GMXB 3A58A 2H7DA 4MY6A 1X1FA 2RNRB 4HAUB 2YRYA 5JHHA 3PZDA 5JHGA 4QJ3B 1AQCA 3QWMA 3TO1A 3NWFA 2DN6A 3ODOA 4HAVB 3ULBA 2LOZA 3DXCA 3P7ZA 1RRPB 3X23A 4GZUA 4HB4B 5D3XA 2D4QA 3PVUA 1BTKA 3SNHA 1I7AA 2RUKB 1P3RA 2R09A 2JP2A 2VRWB 3FEHA 1LB1A 5LG4B 4NY0A 1KI1B 3ODXA 3MPXA 4HHVA 1KZ7A 2KUPA 2GS0A 1FGZA 1TQZA 2DHIA 1Y19B 3TFMA 2BCJA 3WA0A 5C5BA 2L2IA 2EMSA 2D11A 2K2JA 2ROZB 1B55A 1OQNA 1EGXA 2YSZA 1WGUA 5DH9B 4DX90 1FHWA 4WVFB 1EF1A 1DDMA 3BJIA 3RCPA 4KHOA 1FGYA 2W2XD 2KUQA 4XWXA 2LOXA 1WI1A 1TJ6A 2Z0PA 2DX5A 3CIKA 4HDOA 2LYDA 5DIFB 2I1KA 4GPTB 4QXAB 3HIEA 2K2UA 2ZKMX 2K00A 1LW3A 3SV1A 2J0KA 2XQNM 2W2WA 1NU2A 2VKIA 1XKEA 5C6RA 2DHKA 5KQ4A 1DDWA 4K81A 4A6KA 4ZRIA 3N7CA 1MAIA 3AJ4A 4ZRKA 2L1CA 2K8EA 5CLLB 4Z2MB 2K49A 3ZVRA 1H10A 1XODA 5IRSA 5FI1A 2ZPYA 4PNKA 1DDVA 1V61A 4CHJA 2NZ8B 1WGQA 3ML4A 1U29A 2R0DA 3SO6A 5C79A 1UPRA 3BINA 3FM8C 2N23A 2P0HA 2OTXA 1MIZB 5J3QA 5HE1A 4CSQA 3DXEA 2D9XA 1OMWA 3TVVA 1QQGA 4YONA 1NTYA 1WJMA 2D9YA 4EJNA 1MK9B 5JLJB 1NI2A 2NBVA 2J0JA 2LULA 1WG7A 2CY5A 4YL8A 2YT1A 1IRSA 1MK7B 3F5RA 2Q13A 3B77A 3D8EA 1U27A 3GYPA 1U5GA 1X86A 4K2PA 2COFA 2KIEA 4K2OA 3SYXA 2D9VA 5M4YB 1MPHA 2J59M 4IOYX 1ZVRA 3D8DA 4HAYB 4WJ7A 4WSFA 1PFJA 3UZTA 2ADZA 2I1JA 1P5TA 4KVGB 4P7IA 1ZYIA 1W1GA 4TKNA 3TW1A 2COAA 2Z4DA 5CLQB 2YVCA 4B6HA 1FB8A 2IYBA 2D9ZA 1T77A 2KCJA 4HB3B 4KHBA 4L1RA 1W1HA 3T06A 1V5PA 3KSYA 3KRXA 3HQCA 3VIAA 4MK0A 5HE3A 2Y8FA 1ISNA 3LJUX 1XCGA 1SHCA 1AWEA 3F0WA 4HDQA 3GYOA 4GOUA 3WYFB 1U2BA 5I2SA 1X05A 2COCA 3G9WA 4GXBA 2DKQA 4DIXA 1FHXA 1WVHA 3O96A 5L81A 1PMSA 3ULCA 1U5EA 2FJUB 3PP2A 5J3TA 4EKUA 2G35A 1EAZA 1UNRA 3OHMB 1N3HA 4L6EA 2OQBA 4QJ4B 2R2YA 2Z0QA 2DFKA 5J3YA 4A6HA 3MDBC 3KZ1A 3U7DA 3AU4A 1TXDA 3U12A 2Y8GA 1PLSA 1X11A 1ZC3B 2RVBB 2LKOA 3QBVB 4IAPA 2RSGA 4KHBB 1OY2A 2D2QA 4D6WA 2RLOA 2MFQA 3PVWA 1E5WA 4HB2B 5DI9B 2CODA 5DHAB 1ZSQA 2ELBA 2RRFA 1BAKA 2MKRA 2D10A 1J19A 2H7EA 2EC1A 3TCAA 1K5GB 5I2MA 5EFXA 1J0WA 2QKLA 3KRWA 1FAOA 1DROA 2GCJA 1EVHA 3ODWA 3PVLA 2VSZA 4ZRJA 2NMBA 3KY9A 4A6FA 2DTCA 2PZ1A 4HATB 2V76A 3FVCA 2P0DA 1FHOA 4MT7A 5DHFB 4NSWA 1SGHA 3D8FA 4HSIA 2AEHA 3DCXA 3PG7A 5FI0A 3V5WA 3NWAA 1DBHA 1WJ1A 3SUZA 1XX0A 2Z59A 1V89A 4PQ0A 4HAWB 1GC7A 1GG3A 4HAXB 2M14A 4DXAB 5D3WA 1BWNA 3CXBB 2P8VA 2DA0A 5HE0A 1MIXA 3OANA 4HAZB 3NSUA 5D3YA 2DYNA 3PSCA 4KHAA 2YS1A 2KR0A 4F7UP 1ZM0A 3PEGA 5GOWB 4OT1A 2D9WA 3HSAA 2ELAA 2KIGA 1V5UA 1I2HA 4A6FB
chains in the Genus database with same CATH topology
2CY4A 1V88A 4C0AA 1XD4A 3U8ZA 1M7RA 2Y7BA 4CHMA 2I5CA 5C16A 5HE2A 3P6AA 4HB0B 1DYNA 1QC6A 4Z2NA 1K5DB 5D27A 2RGNB 2HTHB 2CAYA 1UNQA 1FOEA 2E2XA 5KCVA 2FJLA 5LOPB 4GN1A 1KZGA 3HW2B 2YT0A 2I5FA 2GJYA 4F7HA 2HE7A 2LG1A 1X1GA 1U5DA 3VOQA 1XR0B 4DX8A 2DYQA 3A98B 1UNPA 3DXDA 5KQ1A 5LONB 2MWNB 2GCLA 3A8PA 1MKEA 4D0NB 1U5FA 2N0YA 2DHJA 2Z0OA 2UZRA 2UZSA 2X18A 1Z87A 3FSSA 3M1IB 4H8SA 1W1DA 2UVMA 1V5MA 2EJ8A 1UPQA 2J0MA 2DLWA 1ZC4B 3IVFA 2EMTA 4EMOA 4TYZA 4DBBA 2YF0A 3AU5A 2MDXA 2KGXB 3QIJA 1GC6A 2DKPA 2YS5A 2ROVA 4CYEA 1P6SA 3A8QA 5C5BB 1Y5OA 1M7EA 2DX1A 1H4RA 4F7GA 1RJ2A 2YS3A 2IFSA 2P0FA 3HK0A 1BTNA 2CRFA 5JP4A 4KAXB 1NTVA 2AL6A 4K17A 2M38A 2W2XC 4BBKA 2QKMA 4Y94A 4GMVA 4IFSA 5D3VA 3ZDTA 1UEFA 4A5KA 1Q67A 4GMXB 2H7DA 4MY6A 1X1FA 2RNRB 4HAUB 2YRYA 5JHHA 3PZDA 5JHGA 1AQCA 3QWMA 3TO1A 2DN6A 3ODOA 4HAVB 3ULBA 2LOZA 3DXCA 3P7ZA 1RRPB 3X23A 4GZUA 4HB4B 5D3XA 2D4QA 3PVUA 1BTKA 3SNHA 1I7AA 2RUKB 1P3RA 2R09A 2JP2A 2VRWB 3FEHA 1LB1A 4NY0A 1KI1B 3ODXA 3MPXA 4HHVA 1KZ7A 2KUPA 2GS0A 1FGZA 1TQZA 2DHIA 1Y19B 3TFMA 2BCJA 3WA0A 5C5BA 2L2IA 2EMSA 2D11A 2K2JA 2ROZB 1B55A 1OQNA 1EGXA 2YSZA 1WGUA 5DH9B 4DX90 1FHWA 4WVFB 1EF1A 1DDMA 3BJIA 3RCPA 4KHOA 1FGYA 2W2XD 4XWXA 2LOXA 1WI1A 1TJ6A 2Z0PA 2DX5A 3CIKA 4HDOA 2LYDA 5DIFB 2I1KA 4GPTB 2K2UA 2K00A 1LW3A 3SV1A 2J0KA 2XQNM 2W2WA 1NU2A 2VKIA 1XKEA 5C6RA 2DHKA 5KQ4A 1DDWA 4K81A 4A6KA 4ZRIA 3N7CA 1MAIA 3AJ4A 4ZRKA 2L1CA 5CLLB 4Z2MB 3ZVRA 1H10A 1XODA 5FI1A 2ZPYA 4PNKA 1DDVA 1V61A 4CHJA 2NZ8B 1WGQA 3ML4A 1U29A 2R0DA 3SO6A 5C79A 1UPRA 3BINA 3FM8C 2N23A 2P0HA 2OTXA 1MIZB 5J3QA 5HE1A 3DXEA 2D9XA 1OMWA 3TVVA 1QQGA 4YONA 1NTYA 1WJMA 2D9YA 4EJNA 1MK9B 5JLJB 1NI2A 2J0JA 2LULA 1WG7A 2CY5A 4YL8A 2YT1A 1IRSA 1MK7B 3F5RA 2Q13A 3D8EA 1U27A 3GYPA 1U5GA 1X86A 4K2PA 2COFA 3SYXA 4K2OA 2D9VA 1MPHA 2J59M 4IOYX 1ZVRA 3D8DA 4HAYB 4WJ7A 4WSFA 1PFJA 3UZTA 2ADZA 2I1JA 1P5TA 4KVGB 4P7IA 1W1GA 4TKNA 3TW1A 2COAA 5CLQB 2YVCA 4B6HA 1FB8A 2IYBA 2D9ZA 4HB3B 2KCJA 1W1HA 3T06A 1V5PA 3KSYA 3KRXA 3HQCA 3VIAA 4MK0A 5HE3A 2Y8FA 1ISNA 3LJUX 1XCGA 1SHCA 1AWEA 3F0WA 4HDQA 3GYOA 3WYFB 1U2BA 1X05A 2COCA 3G9WA 4GXBA 2DKQA 1FHXA 1WVHA 3O96A 5L81A 1PMSA 3ULCA 1U5EA 3PP2A 5J3TA 4EKUA 2G35A 1EAZA 1UNRA 1N3HA 4L6EA 2OQBA 2Z0QA 2DFKA 5J3YA 4A6HA 3MDBC 3KZ1A 3U7DA 3AU4A 1TXDA 2Y8GA 1PLSA 1X11A 1ZC3B 2RVBB 2LKOA 3QBVB 4IAPA 2RSGA 4KHBB 1OY2A 2D2QA 2RLOA 2MFQA 3PVWA 1E5WA 4HB2B 5DI9B 2CODA 5DHAB 1ZSQA 2ELBA 1BAKA 2MKRA 2D10A 1J19A 2H7EA 2EC1A 3TCAA 1K5GB 5EFXA 1J0WA 2QKLA 3KRWA 1FAOA 1DROA 2GCJA 1EVHA 3ODWA 3PVLA 2VSZA 4ZRJA 2NMBA 3KY9A 4A6FA 2DTCA 2PZ1A 4HATB 2V76A 2P0DA 1FHOA 4MT7A 5DHFB 4NSWA 1SGHA 3D8FA 2AEHA 3PG7A 5FI0A 3V5WA 1DBHA 1WJ1A 3SUZA 1XX0A 1V89A 4PQ0A 4HAWB 1GC7A 1GG3A 4HAXB 2M14A 4DXAB 5D3WA 1BWNA 3CXBB 2P8VA 2DA0A 5HE0A 1MIXA 3OANA 4HAZB 3NSUA 5D3YA 2DYNA 3PSCA 4KHAA 2YS1A 4F7UP 1ZM0A 3PEGA 5GOWB 2D9WA 2ELAA 1V5UA 1I2HA 4A6FB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CY4 A;  1V88 A;  4C0A A;  1XD4 A;  3U8Z A;  1M7R A;  2Y7B A;  4CHM A;  2I5C A;  5C16 A;  5HE2 A;  3P6A A;  4HB0 B;  1DYN A;  1QC6 A;  4Z2N A;  1K5D B;  5D27 A;  2RGN B;  2HTH B;  2CAY A;  1UNQ A;  1FOE A;  2E2X A;  5KCV A;  2FJL A;  5LOP B;  4GN1 A;  1KZG A;  3HW2 B;  2YT0 A;  2I5F A;  2GJY A;  4F7H A;  2HE7 A;  2LG1 A;  1X1G A;  1U5D A;  3VOQ A;  1XR0 B;  4DX8 A;  2DYQ A;  3A98 B;  1UNP A;  3DXD A;  5KQ1 A;  5LON B;  2MWN B;  2GCL A;  3A8P A;  1MKE A;  4D0N B;  1U5F A;  2N0Y A;  2DHJ A;  2Z0O A;  2UZR A;  2UZS A;  2X18 A;  1Z87 A;  3FSS A;  3M1I B;  4H8S A;  1W1D A;  2UVM A;  1V5M A;  2EJ8 A;  1UPQ A;  2J0M A;  2DLW A;  1ZC4 B;  3IVF A;  2EMT A;  4EMO A;  4TYZ A;  4DBB A;  2YF0 A;  3AU5 A;  2MDX A;  2KGX B;  3QIJ A;  1GC6 A;  2DKP A;  2YS5 A;  2ROV A;  4CYE A;  1P6S A;  3A8Q A;  5C5B B;  1Y5O A;  1M7E A;  2DX1 A;  1H4R A;  4F7G A;  1RJ2 A;  2YS3 A;  2IFS A;  2P0F A;  3HK0 A;  1BTN A;  2CRF A;  5JP4 A;  4KAX B;  1NTV A;  2AL6 A;  4K17 A;  2M38 A;  2W2X C;  4BBK A;  2QKM A;  4Y94 A;  4GMV A;  4IFS A;  5D3V A;  3ZDT A;  1UEF A;  4A5K A;  1Q67 A;  4GMX B;  2H7D A;  4MY6 A;  1X1F A;  2RNR B;  4HAU B;  2YRY A;  5JHH A;  3PZD A;  5JHG A;  1AQC A;  3QWM A;  3TO1 A;  2DN6 A;  3ODO A;  4HAV B;  3ULB A;  2LOZ A;  3DXC A;  3P7Z A;  1RRP B;  3X23 A;  4GZU A;  4HB4 B;  5D3X A;  2D4Q A;  3PVU A;  1BTK A;  3SNH A;  1I7A A;  2RUK B;  1P3R A;  2R09 A;  2JP2 A;  2VRW B;  3FEH A;  1LB1 A;  4NY0 A;  1KI1 B;  3ODX A;  3MPX A;  4HHV A;  1KZ7 A;  2KUP A;  2GS0 A;  1FGZ A;  1TQZ A;  2DHI A;  1Y19 B;  3TFM A;  2BCJ A;  3WA0 A;  5C5B A;  2L2I A;  2EMS A;  2D11 A;  2K2J A;  2ROZ B;  1B55 A;  1OQN A;  1EGX A;  2YSZ A;  1WGU A;  5DH9 B;  4DX9 0;  1FHW A;  4WVF B;  1EF1 A;  1DDM A;  3BJI A;  3RCP A;  4KHO A;  1FGY A;  2W2X D;  4XWX A;  2LOX A;  1WI1 A;  1TJ6 A;  2Z0P A;  2DX5 A;  3CIK A;  4HDO A;  2LYD A;  5DIF B;  2I1K A;  4GPT B;  2K2U A;  2K00 A;  1LW3 A;  3SV1 A;  2J0K A;  2XQN M;  2W2W A;  1NU2 A;  2VKI A;  1XKE A;  5C6R A;  2DHK A;  5KQ4 A;  1DDW A;  4K81 A;  4A6K A;  4ZRI A;  3N7C A;  1MAI A;  3AJ4 A;  4ZRK A;  2L1C A;  5CLL B;  4Z2M B;  3ZVR A;  1H10 A;  1XOD A;  5FI1 A;  2ZPY A;  4PNK A;  1DDV A;  1V61 A;  4CHJ A;  2NZ8 B;  1WGQ A;  3ML4 A;  1U29 A;  2R0D A;  3SO6 A;  5C79 A;  1UPR A;  3BIN A;  3FM8 C;  2N23 A;  2P0H A;  2OTX A;  1MIZ B;  5J3Q A;  5HE1 A;  3DXE A;  2D9X A;  1OMW A;  3TVV A;  1QQG A;  4YON A;  1NTY A;  1WJM A;  2D9Y A;  4EJN A;  1MK9 B;  5JLJ B;  1NI2 A;  2J0J A;  2LUL A;  1WG7 A;  2CY5 A;  4YL8 A;  2YT1 A;  1IRS A;  1MK7 B;  3F5R A;  2Q13 A;  3D8E A;  1U27 A;  3GYP A;  1U5G A;  1X86 A;  4K2P A;  2COF A;  3SYX A;  4K2O A;  2D9V A;  1MPH A;  2J59 M;  4IOY X;  1ZVR A;  3D8D A;  4HAY B;  4WJ7 A;  4WSF A;  1PFJ A;  3UZT A;  2ADZ A;  2I1J A;  1P5T A;  4KVG B;  4P7I A;  1W1G A;  4TKN A;  3TW1 A;  2COA A;  5CLQ B;  2YVC A;  4B6H A;  1FB8 A;  2IYB A;  2D9Z A;  4HB3 B;  2KCJ A;  1W1H A;  3T06 A;  1V5P A;  3KSY A;  3KRX A;  3HQC A;  3VIA A;  4MK0 A;  5HE3 A;  2Y8F A;  1ISN A;  3LJU X;  1XCG A;  1SHC A;  1AWE A;  3F0W A;  4HDQ A;  3GYO A;  3WYF B;  1U2B A;  1X05 A;  2COC A;  3G9W A;  4GXB A;  2DKQ A;  1FHX A;  1WVH A;  3O96 A;  5L81 A;  1PMS A;  3ULC A;  1U5E A;  3PP2 A;  5J3T A;  4EKU A;  2G35 A;  1EAZ A;  1UNR A;  1N3H A;  4L6E A;  2OQB A;  2Z0Q A;  2DFK A;  5J3Y A;  4A6H A;  3MDB C;  3KZ1 A;  3U7D A;  3AU4 A;  1TXD A;  2Y8G A;  1PLS A;  1X11 A;  1ZC3 B;  2RVB B;  2LKO A;  3QBV B;  4IAP A;  2RSG A;  4KHB B;  1OY2 A;  2D2Q A;  2RLO A;  2MFQ A;  3PVW A;  1E5W A;  4HB2 B;  5DI9 B;  2COD A;  5DHA B;  1ZSQ A;  2ELB A;  1BAK A;  2MKR A;  2D10 A;  1J19 A;  2H7E A;  2EC1 A;  3TCA A;  1K5G B;  5EFX A;  1J0W A;  2QKL A;  3KRW A;  1FAO A;  1DRO A;  2GCJ A;  1EVH A;  3ODW A;  3PVL A;  2VSZ A;  4ZRJ A;  2NMB A;  3KY9 A;  4A6F A;  2DTC A;  2PZ1 A;  4HAT B;  2V76 A;  2P0D A;  1FHO A;  4MT7 A;  5DHF B;  4NSW A;  1SGH A;  3D8F A;  2AEH A;  3PG7 A;  5FI0 A;  3V5W A;  1DBH A;  1WJ1 A;  3SUZ A;  1XX0 A;  1V89 A;  4PQ0 A;  4HAW B;  1GC7 A;  1GG3 A;  4HAX B;  2M14 A;  4DXA B;  5D3W A;  1BWN A;  3CXB B;  2P8V A;  2DA0 A;  5HE0 A;  1MIX A;  3OAN A;  4HAZ B;  3NSU A;  5D3Y A;  2DYN A;  3PSC A;  4KHA A;  2YS1 A;  4F7U P;  1ZM0 A;  3PEG A;  5GOW B;  2D9W A;  2ELA A;  1V5U A;  1I2H A;  4A6F B; 
#chains in the Genus database with same CATH topology
 2CY4 A;  1V88 A;  4C0A A;  1XD4 A;  3U8Z A;  1M7R A;  2Y7B A;  4CHM A;  2I5C A;  5C16 A;  5HE2 A;  3P6A A;  4HB0 B;  1DYN A;  1QC6 A;  4Z2N A;  1K5D B;  3NWD A;  3NW8 A;  5D27 A;  2RGN B;  2HTH B;  2CAY A;  1UNQ A;  1FOE A;  2E2X A;  5KCV A;  2FJL A;  5LOP B;  4GN1 A;  1KZG A;  3HW2 B;  2YT0 A;  2I5F A;  2GJY A;  4F7H A;  4OSN A;  2HE7 A;  2LG1 A;  1X1G A;  1U5D A;  3VOQ A;  1XR0 B;  4DX8 A;  2DYQ A;  3A98 B;  1UNP A;  3DXD A;  5KQ1 A;  5LON B;  2MWN B;  2GCL A;  3A8P A;  1MKE A;  4D0N B;  1U5F A;  2N0Y A;  2DHJ A;  2Z0O A;  2UZR A;  2UZS A;  2X18 A;  1Z87 A;  3FSS A;  3M1I B;  4H8S A;  1W1D A;  2UVM A;  1V5M A;  2EJ8 A;  1UPQ A;  2J0M A;  2DLW A;  1ZC4 B;  3IVF A;  2EMT A;  4EMO A;  4TYZ A;  1MI1 A;  4DBB A;  2YF0 A;  3AU5 A;  2MDX A;  2KGX B;  3QIJ A;  1GC6 A;  2YT2 A;  2DKP A;  2YS5 A;  2ROV A;  4CYE A;  1P6S A;  3A8Q A;  5C5B B;  1Y5O A;  1M7E A;  2DX1 A;  1H4R A;  4F7G A;  1RJ2 A;  2YS3 A;  2IFS A;  2P0F A;  3HK0 A;  4QJ5 B;  1BTN A;  2CRF A;  5JP4 A;  2Z13 A;  4KAX B;  2Z14 A;  1NTV A;  2AL6 A;  4K17 A;  2M38 A;  2W2X C;  4BBK A;  2QKM A;  4Y94 A;  2GUM A;  4GMV A;  4IFS A;  5D3V A;  3ZDT A;  4GNK B;  1UEF A;  4A5K A;  1Q67 A;  4GMX B;  3A58 A;  2H7D A;  4MY6 A;  1X1F A;  2RNR B;  4HAU B;  2YRY A;  5JHH A;  3PZD A;  5JHG A;  4QJ3 B;  1AQC A;  3QWM A;  3TO1 A;  3NWF A;  2DN6 A;  3ODO A;  4HAV B;  3ULB A;  2LOZ A;  3DXC A;  3P7Z A;  1RRP B;  3X23 A;  4GZU A;  4HB4 B;  5D3X A;  2D4Q A;  3PVU A;  1BTK A;  3SNH A;  1I7A A;  2RUK B;  1P3R A;  2R09 A;  2JP2 A;  2VRW B;  3FEH A;  1LB1 A;  5LG4 B;  4NY0 A;  1KI1 B;  3ODX A;  3MPX A;  4HHV A;  1KZ7 A;  2KUP A;  2GS0 A;  1FGZ A;  1TQZ A;  2DHI A;  1Y19 B;  3TFM A;  2BCJ A;  3WA0 A;  5C5B A;  2L2I A;  2EMS A;  2D11 A;  2K2J A;  2ROZ B;  1B55 A;  1OQN A;  1EGX A;  2YSZ A;  1WGU A;  5DH9 B;  4DX9 0;  1FHW A;  4WVF B;  1EF1 A;  1DDM A;  3BJI A;  3RCP A;  4KHO A;  1FGY A;  2W2X D;  2KUQ A;  4XWX A;  2LOX A;  1WI1 A;  1TJ6 A;  2Z0P A;  2DX5 A;  3CIK A;  4HDO A;  2LYD A;  5DIF B;  2I1K A;  4GPT B;  4QXA B;  3HIE A;  2K2U A;  2ZKM X;  2K00 A;  1LW3 A;  3SV1 A;  2J0K A;  2XQN M;  2W2W A;  1NU2 A;  2VKI A;  1XKE A;  5C6R A;  2DHK A;  5KQ4 A;  1DDW A;  4K81 A;  4A6K A;  4ZRI A;  3N7C A;  1MAI A;  3AJ4 A;  4ZRK A;  2L1C A;  2K8E A;  5CLL B;  4Z2M B;  2K49 A;  3ZVR A;  1H10 A;  1XOD A;  5IRS A;  5FI1 A;  2ZPY A;  4PNK A;  1DDV A;  1V61 A;  4CHJ A;  2NZ8 B;  1WGQ A;  3ML4 A;  1U29 A;  2R0D A;  3SO6 A;  5C79 A;  1UPR A;  3BIN A;  3FM8 C;  2N23 A;  2P0H A;  2OTX A;  1MIZ B;  5J3Q A;  5HE1 A;  4CSQ A;  3DXE A;  2D9X A;  1OMW A;  3TVV A;  1QQG A;  4YON A;  1NTY A;  1WJM A;  2D9Y A;  4EJN A;  1MK9 B;  5JLJ B;  1NI2 A;  2NBV A;  2J0J A;  2LUL A;  1WG7 A;  2CY5 A;  4YL8 A;  2YT1 A;  1IRS A;  1MK7 B;  3F5R A;  2Q13 A;  3B77 A;  3D8E A;  1U27 A;  3GYP A;  1U5G A;  1X86 A;  4K2P A;  2COF A;  2KIE A;  4K2O A;  3SYX A;  2D9V A;  5M4Y B;  1MPH A;  2J59 M;  4IOY X;  1ZVR A;  3D8D A;  4HAY B;  4WJ7 A;  4WSF A;  1PFJ A;  3UZT A;  2ADZ A;  2I1J A;  1P5T A;  4KVG B;  4P7I A;  1ZYI A;  1W1G A;  4TKN A;  3TW1 A;  2COA A;  2Z4D A;  5CLQ B;  2YVC A;  4B6H A;  1FB8 A;  2IYB A;  2D9Z A;  1T77 A;  2KCJ A;  4HB3 B;  4KHB A;  4L1R A;  1W1H A;  3T06 A;  1V5P A;  3KSY A;  3KRX A;  3HQC A;  3VIA A;  4MK0 A;  5HE3 A;  2Y8F A;  1ISN A;  3LJU X;  1XCG A;  1SHC A;  1AWE A;  3F0W A;  4HDQ A;  3GYO A;  4GOU A;  3WYF B;  1U2B A;  5I2S A;  1X05 A;  2COC A;  3G9W A;  4GXB A;  2DKQ A;  4DIX A;  1FHX A;  1WVH A;  3O96 A;  5L81 A;  1PMS A;  3ULC A;  1U5E A;  2FJU B;  3PP2 A;  5J3T A;  4EKU A;  2G35 A;  1EAZ A;  1UNR A;  3OHM B;  1N3H A;  4L6E A;  2OQB A;  4QJ4 B;  2R2Y A;  2Z0Q A;  2DFK A;  5J3Y A;  4A6H A;  3MDB C;  3KZ1 A;  3U7D A;  3AU4 A;  1TXD A;  3U12 A;  2Y8G A;  1PLS A;  1X11 A;  1ZC3 B;  2RVB B;  2LKO A;  3QBV B;  4IAP A;  2RSG A;  4KHB B;  1OY2 A;  2D2Q A;  4D6W A;  2RLO A;  2MFQ A;  3PVW A;  1E5W A;  4HB2 B;  5DI9 B;  2COD A;  5DHA B;  1ZSQ A;  2ELB A;  2RRF A;  1BAK A;  2MKR A;  2D10 A;  1J19 A;  2H7E A;  2EC1 A;  3TCA A;  1K5G B;  5I2M A;  5EFX A;  1J0W A;  2QKL A;  3KRW A;  1FAO A;  1DRO A;  2GCJ A;  1EVH A;  3ODW A;  3PVL A;  2VSZ A;  4ZRJ A;  2NMB A;  3KY9 A;  4A6F A;  2DTC A;  2PZ1 A;  4HAT B;  2V76 A;  3FVC A;  2P0D A;  1FHO A;  4MT7 A;  5DHF B;  4NSW A;  1SGH A;  3D8F A;  4HSI A;  2AEH A;  3DCX A;  3PG7 A;  5FI0 A;  3V5W A;  3NWA A;  1DBH A;  1WJ1 A;  3SUZ A;  1XX0 A;  2Z59 A;  1V89 A;  4PQ0 A;  4HAW B;  1GC7 A;  1GG3 A;  4HAX B;  2M14 A;  4DXA B;  5D3W A;  1BWN A;  3CXB B;  2P8V A;  2DA0 A;  5HE0 A;  1MIX A;  3OAN A;  4HAZ B;  3NSU A;  5D3Y A;  2DYN A;  3PSC A;  4KHA A;  2YS1 A;  2KR0 A;  4F7U P;  1ZM0 A;  3PEG A;  5GOW B;  4OT1 A;  2D9W A;  3HSA A;  2ELA A;  2KIG A;  1V5U A;  1I2H A;  4A6F B; 
#chains in the Genus database with same CATH homology
 2CY4 A;  1V88 A;  4C0A A;  1XD4 A;  3U8Z A;  1M7R A;  2Y7B A;  4CHM A;  2I5C A;  5C16 A;  5HE2 A;  3P6A A;  4HB0 B;  1DYN A;  1QC6 A;  4Z2N A;  1K5D B;  5D27 A;  2RGN B;  2HTH B;  2CAY A;  1UNQ A;  1FOE A;  2E2X A;  5KCV A;  2FJL A;  5LOP B;  4GN1 A;  1KZG A;  3HW2 B;  2YT0 A;  2I5F A;  2GJY A;  4F7H A;  2HE7 A;  2LG1 A;  1X1G A;  1U5D A;  3VOQ A;  1XR0 B;  4DX8 A;  2DYQ A;  3A98 B;  1UNP A;  3DXD A;  5KQ1 A;  5LON B;  2MWN B;  2GCL A;  3A8P A;  1MKE A;  4D0N B;  1U5F A;  2N0Y A;  2DHJ A;  2Z0O A;  2UZR A;  2UZS A;  2X18 A;  1Z87 A;  3FSS A;  3M1I B;  4H8S A;  1W1D A;  2UVM A;  1V5M A;  2EJ8 A;  1UPQ A;  2J0M A;  2DLW A;  1ZC4 B;  3IVF A;  2EMT A;  4EMO A;  4TYZ A;  4DBB A;  2YF0 A;  3AU5 A;  2MDX A;  2KGX B;  3QIJ A;  1GC6 A;  2DKP A;  2YS5 A;  2ROV A;  4CYE A;  1P6S A;  3A8Q A;  5C5B B;  1Y5O A;  1M7E A;  2DX1 A;  1H4R A;  4F7G A;  1RJ2 A;  2YS3 A;  2IFS A;  2P0F A;  3HK0 A;  1BTN A;  2CRF A;  5JP4 A;  4KAX B;  1NTV A;  2AL6 A;  4K17 A;  2M38 A;  2W2X C;  4BBK A;  2QKM A;  4Y94 A;  4GMV A;  4IFS A;  5D3V A;  3ZDT A;  1UEF A;  4A5K A;  1Q67 A;  4GMX B;  2H7D A;  4MY6 A;  1X1F A;  2RNR B;  4HAU B;  2YRY A;  5JHH A;  3PZD A;  5JHG A;  1AQC A;  3QWM A;  3TO1 A;  2DN6 A;  3ODO A;  4HAV B;  3ULB A;  2LOZ A;  3DXC A;  3P7Z A;  1RRP B;  3X23 A;  4GZU A;  4HB4 B;  5D3X A;  2D4Q A;  3PVU A;  1BTK A;  3SNH A;  1I7A A;  2RUK B;  1P3R A;  2R09 A;  2JP2 A;  2VRW B;  3FEH A;  1LB1 A;  4NY0 A;  1KI1 B;  3ODX A;  3MPX A;  4HHV A;  1KZ7 A;  2KUP A;  2GS0 A;  1FGZ A;  1TQZ A;  2DHI A;  1Y19 B;  3TFM A;  2BCJ A;  3WA0 A;  5C5B A;  2L2I A;  2EMS A;  2D11 A;  2K2J A;  2ROZ B;  1B55 A;  1OQN A;  1EGX A;  2YSZ A;  1WGU A;  5DH9 B;  4DX9 0;  1FHW A;  4WVF B;  1EF1 A;  1DDM A;  3BJI A;  3RCP A;  4KHO A;  1FGY A;  2W2X D;  4XWX A;  2LOX A;  1WI1 A;  1TJ6 A;  2Z0P A;  2DX5 A;  3CIK A;  4HDO A;  2LYD A;  5DIF B;  2I1K A;  4GPT B;  2K2U A;  2K00 A;  1LW3 A;  3SV1 A;  2J0K A;  2XQN M;  2W2W A;  1NU2 A;  2VKI A;  1XKE A;  5C6R A;  2DHK A;  5KQ4 A;  1DDW A;  4K81 A;  4A6K A;  4ZRI A;  3N7C A;  1MAI A;  3AJ4 A;  4ZRK A;  2L1C A;  5CLL B;  4Z2M B;  3ZVR A;  1H10 A;  1XOD A;  5FI1 A;  2ZPY A;  4PNK A;  1DDV A;  1V61 A;  4CHJ A;  2NZ8 B;  1WGQ A;  3ML4 A;  1U29 A;  2R0D A;  3SO6 A;  5C79 A;  1UPR A;  3BIN A;  3FM8 C;  2N23 A;  2P0H A;  2OTX A;  1MIZ B;  5J3Q A;  5HE1 A;  3DXE A;  2D9X A;  1OMW A;  3TVV A;  1QQG A;  4YON A;  1NTY A;  1WJM A;  2D9Y A;  4EJN A;  1MK9 B;  5JLJ B;  1NI2 A;  2J0J A;  2LUL A;  1WG7 A;  2CY5 A;  4YL8 A;  2YT1 A;  1IRS A;  1MK7 B;  3F5R A;  2Q13 A;  3D8E A;  1U27 A;  3GYP A;  1U5G A;  1X86 A;  4K2P A;  2COF A;  3SYX A;  4K2O A;  2D9V A;  1MPH A;  2J59 M;  4IOY X;  1ZVR A;  3D8D A;  4HAY B;  4WJ7 A;  4WSF A;  1PFJ A;  3UZT A;  2ADZ A;  2I1J A;  1P5T A;  4KVG B;  4P7I A;  1W1G A;  4TKN A;  3TW1 A;  2COA A;  5CLQ B;  2YVC A;  4B6H A;  1FB8 A;  2IYB A;  2D9Z A;  4HB3 B;  2KCJ A;  1W1H A;  3T06 A;  1V5P A;  3KSY A;  3KRX A;  3HQC A;  3VIA A;  4MK0 A;  5HE3 A;  2Y8F A;  1ISN A;  3LJU X;  1XCG A;  1SHC A;  1AWE A;  3F0W A;  4HDQ A;  3GYO A;  3WYF B;  1U2B A;  1X05 A;  2COC A;  3G9W A;  4GXB A;  2DKQ A;  1FHX A;  1WVH A;  3O96 A;  5L81 A;  1PMS A;  3ULC A;  1U5E A;  3PP2 A;  5J3T A;  4EKU A;  2G35 A;  1EAZ A;  1UNR A;  1N3H A;  4L6E A;  2OQB A;  2Z0Q A;  2DFK A;  5J3Y A;  4A6H A;  3MDB C;  3KZ1 A;  3U7D A;  3AU4 A;  1TXD A;  2Y8G A;  1PLS A;  1X11 A;  1ZC3 B;  2RVB B;  2LKO A;  3QBV B;  4IAP A;  2RSG A;  4KHB B;  1OY2 A;  2D2Q A;  2RLO A;  2MFQ A;  3PVW A;  1E5W A;  4HB2 B;  5DI9 B;  2COD A;  5DHA B;  1ZSQ A;  2ELB A;  1BAK A;  2MKR A;  2D10 A;  1J19 A;  2H7E A;  2EC1 A;  3TCA A;  1K5G B;  5EFX A;  1J0W A;  2QKL A;  3KRW A;  1FAO A;  1DRO A;  2GCJ A;  1EVH A;  3ODW A;  3PVL A;  2VSZ A;  4ZRJ A;  2NMB A;  3KY9 A;  4A6F A;  2DTC A;  2PZ1 A;  4HAT B;  2V76 A;  2P0D A;  1FHO A;  4MT7 A;  5DHF B;  4NSW A;  1SGH A;  3D8F A;  2AEH A;  3PG7 A;  5FI0 A;  3V5W A;  1DBH A;  1WJ1 A;  3SUZ A;  1XX0 A;  1V89 A;  4PQ0 A;  4HAW B;  1GC7 A;  1GG3 A;  4HAX B;  2M14 A;  4DXA B;  5D3W A;  1BWN A;  3CXB B;  2P8V A;  2DA0 A;  5HE0 A;  1MIX A;  3OAN A;  4HAZ B;  3NSU A;  5D3Y A;  2DYN A;  3PSC A;  4KHA A;  2YS1 A;  4F7U P;  1ZM0 A;  3PEG A;  5GOW B;  2D9W A;  2ELA A;  1V5U A;  1I2H A;  4A6F B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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