5D27A

Crystal structure of the p-rex1 ph domain
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
166
structure length
154
Chain Sequence
GEFEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKSKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKLGMERDAYV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac excha
publication title Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Lipid binding protein
total genus 45
structure length 154
sequence length 166
ec nomenclature
pdb deposition date 2015-08-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 5d27A00
3ODWA 2ADZA 1UPQA 4MY6A 1FOEA 1MK7B 1X1FA 4A6FB 1DBHA 1NTVA 2YS5A 3X23A 1U27A 2MWNB 1MPHA 2D10A 2H7EA 4HAYB 3ODOA 3KRWA 4ZRJA 4DXAB 1P6SA 4WJ7A 1ZSQA 3VOQA 2VKIA 4H8SA 4A6KA 3LJUX 2L1CA 4HB3B 5JP4A 1NTYA 1V5PA 1ZVRA 4EKUA 1BWNA 1UPRA 2AEHA 1OY2A 2CY5A 4GN1A 3DXCA 2Z0QA 5HE1A 3TO1A 3ULCA 3FEHA 3VIAA 1PFJA 5J3YA 4F7GA 1V61A 2Q13A 5FI1A 5LOPB 2LOXA 1MK9B 4HAUB 4GMXB 1DDVA 4ZRIA 1OQNA 5J3QA 2R09A 1V5MA 3DXEA 3UZTA 3ZDTA 4K17A 2RNRB 4EMOA 5CLQB 4L6EA 5C16A 1B55A 1MKEA 1WI1A 1IRSA 4B6HA 4K2OA 5JLJB 1MIXA 3PZDA 2HE7A 2RVBB 4A6FA 2QKLA 4MK0A 2JP2A 2UZSA 2H7DA 1W1DA 2DYQA 2OQBA 4TKNA 1XD4A 3AU4A 2GJYA 1UNQA 2IFSA 4HAXB 4KHBB 1Z87A 4HDQA 2W2WA 5KQ1A 1BAKA 1AWEA 3DXDA 4HB0B 2COFA 2MKRA 1DDWA 2P0HA 4GMVA 2LYDA 3SO6A 2D9ZA 5HE3A 2EC1A 1EVHA 5D3XA 1U2BA 1UNRA 2K00A 3GYOA 1RRPB 1ISNA 4NY0A 2NMBA 4EJNA 1FHWA 2DHKA 3FM8C 3BJIA 4A6HA 2I1JA 2GCLA 1V88A 4KHOA 4DX8A 2Y8GA 5KQ4A 1MIZB 2UVMA 2ELBA 2YS3A 1U5FA 2J59M 1V5UA 4HDOA 5C79A 5D27A 2J0MA 3PSCA 4HAZB 1U29A 2KGXB 1H4RA 1WVHA 2E2XA 2D11A 1UEFA 3M1IB 2NZ8B 3WA0A 2K2UA 5DH9B 2DHIA 1FAOA 1N3HA 3KZ1A 1UNPA 2IYBA 1WGUA 2J0KA 2AL6A 1X05A 4XWXA 1ZM0A 3ULBA 1SHCA 5HE0A 2D9YA 3MDBC 3D8FA 1X11A 4KVGB 3NSUA 4DX90 2MFQA 2EJ8A 2D9XA 3FSSA 1W1HA 1EGXA 1FGYA 2DYNA 2DN6A 4KHAA 1TXDA 4HATB 3ODXA 2M14A 4F7HA 4YONA 3PP2A 5DHFB 1XCGA 4K81A 3KY9A 1NI2A 1P5TA 1J0WA 2K2JA 2L2IA 2LKOA 4WSFA 3SNHA 2RUKB 2UZRA 4DBBA 2X18A 1M7RA 2D4QA 1V89A 1FGZA 2P8VA 2DA0A 3SUZA 2I1KA 3A98B 1EF1A 1WJ1A 2W2XD 1QQGA 1H10A 4C0AA 3CIKA 1DROA 1WG7A 4GPTB 1XX0A 2Y8FA 1PLSA 1WGQA 3KSYA 2DTCA 5DHAB 3QIJA 4CHJA 2LULA 1QC6A 1P3RA 4IFSA 1FB8A 3SYXA 3AJ4A 5D3YA 2MDXA 3TVVA 4A5KA 2CRFA 3PG7A 2V76A 4GXBA 4K2PA 2KCJA 3ZVRA 3PVWA 1BTKA 3TCAA 2RGNB 2KUPA 3U7DA 2FJLA 2OTXA 2ROZB 2COAA 1GC7A 2YSZA 1E5WA 2J0JA 1Y19B 1KZGA 3SV1A 3OANA 1U5GA 2RLOA 1XR0B 2RSGA 2D9VA 5C5BB 5DIFB 1FHXA 2YS1A 5CLLB 4HAWB 2HTHB 1DDMA 1TQZA 1KZ7A 3GYPA 4WVFB 5FI0A 3MPXA 4CYEA 2Z0OA 2ELAA 3HQCA 2P0DA 3QBVB 2I5FA 5J3TA 2DLWA 1W1GA 3ML4A 1DYNA 2DHJA 3HW2B 5JHHA 4HB4B 2G35A 4HB2B 2EMSA 1X86A 5HE2A 2YT1A 4BBKA 1J19A 2R0DA 4KAXB 2Y7BA 4CHMA 2DKPA 3PVLA 1LB1A 2CAYA 3RCPA 3N7CA 1GG3A 5GOWB 3P7ZA 2CY4A 2XQNM 3QWMA 2W2XC 3T06A 1SGHA 5EFXA 4D0NB 2CODA 3G9WA 4ZRKA 2YRYA 3AU5A 4NSWA 2LG1A 1Q67A 3D8DA 1OMWA 1AQCA 2N23A 5C5BA 4Y94A 3TW1A 1TJ6A 3P6AA 3A8PA 2QKMA 2LOZA 3PEGA 2D2QA 2YVCA 2DKQA 2N0YA 4Z2NA 2BCJA 4P7IA 1U5DA 1MAIA 4IOYX 2ZPYA 1K5GB 1NU2A 5D3VA 1FHOA 4PNKA 2COCA 1I7AA 3A8QA 1ZC4B 1GC6A 2VSZA 4HAVB 1XODA 3PVUA 2EMTA 2P0FA 1XKEA 3KRXA 3D8EA 4MT7A 1WJMA 3WYFB 1K5DB 2GS0A 2ROVA 5C6RA 5L81A 3V5WA 1ZC3B 1PMSA 2M38A 2YF0A 1RJ2A 5JHGA 1M7EA 3CXBB 5DI9B 5LONB 1EAZA 4YL8A 2Z0PA 1KI1B 3F5RA 4F7UP 2DX1A 5KCVA 3HK0A 2D9WA 5D3WA 1I2HA 1U5EA 4HHVA 1X1GA 3TFMA 4TYZA 4PQ0A 3F0WA 1BTNA 2VRWB 2GCJA 3BINA 4IAPA 1Y5OA 2DFKA 4Z2MB 3IVFA 2YT0A 4GZUA 2I5CA 3O96A 2DX5A 3U8ZA 1LW3A 2PZ1A
chains in the Genus database with same CATH superfamily
3ODWA 2ADZA 1UPQA 4MY6A 1FOEA 1MK7B 1X1FA 4A6FB 1DBHA 1NTVA 2YS5A 3X23A 1U27A 2MWNB 1MPHA 2D10A 2H7EA 4HAYB 3ODOA 3KRWA 4ZRJA 4DXAB 1P6SA 4WJ7A 1ZSQA 3A58A 3VOQA 2VKIA 4H8SA 4A6KA 3LJUX 2L1CA 4OT1A 2K8EA 4HB3B 5JP4A 1NTYA 1V5PA 1ZVRA 4EKUA 1BWNA 1UPRA 2AEHA 1OY2A 1ZYIA 2CY5A 4GN1A 3DXCA 2Z0QA 5HE1A 3TO1A 3ULCA 3FEHA 3VIAA 1PFJA 5J3YA 4F7GA 1V61A 2Q13A 5FI1A 5LOPB 2LOXA 1MK9B 4HAUB 4GMXB 1DDVA 4ZRIA 1OQNA 3DCXA 4QJ3B 5J3QA 2R09A 2R2YA 1V5MA 2RRFA 3DXEA 3UZTA 3ZDTA 4K17A 2RNRB 4EMOA 5CLQB 4L6EA 5C16A 1B55A 1MKEA 1WI1A 1IRSA 4B6HA 4K2OA 5JLJB 1MIXA 4GNKB 3PZDA 2HE7A 2RVBB 4A6FA 2QKLA 4MK0A 2JP2A 2UZSA 2H7DA 1W1DA 2DYQA 2OQBA 3NWFA 4TKNA 1XD4A 3NWDA 2Z13A 2GJYA 1UNQA 3AU4A 2IFSA 4HAXB 4KHBB 1Z87A 4HDQA 2W2WA 5KQ1A 1BAKA 2KR0A 1AWEA 3DXDA 4HB0B 2COFA 2MKRA 1DDWA 2P0HA 3HIEA 4GMVA 2LYDA 3SO6A 2D9ZA 5HE3A 2EC1A 5I2MA 1EVHA 5D3XA 1U2BA 1UNRA 2K00A 3GYOA 1RRPB 1ISNA 4NY0A 2NMBA 4EJNA 1FHWA 2DHKA 3FM8C 3BJIA 3B77A 4A6HA 2I1JA 2GCLA 1V88A 4KHOA 4DX8A 2Y8GA 5KQ4A 1MIZB 2UVMA 2ELBA 2YS3A 1U5FA 2J59M 1V5UA 2NBVA 4HDOA 5C79A 5D27A 2J0MA 3PSCA 4HAZB 4CSQA 1U29A 2KGXB 1H4RA 1WVHA 2E2XA 2D11A 1UEFA 3M1IB 3FVCA 2NZ8B 3WA0A 2K2UA 5DH9B 2DHIA 1FAOA 1N3HA 3KZ1A 2ZKMX 1UNPA 5IRSA 2IYBA 1WGUA 2J0KA 2AL6A 1X05A 4XWXA 1ZM0A 3ULBA 4KHBA 1SHCA 5HE0A 2D9YA 3MDBC 4L1RA 3D8FA 1X11A 4KVGB 3NSUA 4DX90 2MFQA 2EJ8A 2D9XA 3FSSA 1W1HA 3NWAA 1EGXA 1FGYA 2DYNA 2DN6A 4KHAA 1TXDA 4HATB 3ODXA 2M14A 4F7HA 4QJ4B 4YONA 3PP2A 5DHFB 1XCGA 4K81A 2KIGA 1NI2A 1P5TA 1J0WA 2K2JA 2LKOA 2L2IA 3KY9A 4WSFA 3SNHA 2RUKB 2UZRA 4DBBA 2X18A 1M7RA 2Z59A 2D4QA 1V89A 1FGZA 2P8VA 2DA0A 3SUZA 2I1KA 4OSNA 3A98B 1EF1A 1WJ1A 4GOUA 2W2XD 1QQGA 1H10A 2K49A 4C0AA 3CIKA 1DROA 1WG7A 4GPTB 1XX0A 2Y8FA 1PLSA 1WGQA 3KSYA 2DTCA 5DHAB 3QIJA 4CHJA 2LULA 1QC6A 3OHMB 1P3RA 4IFSA 1FB8A 3SYXA 3AJ4A 5D3YA 2MDXA 2FJUB 3TVVA 4A5KA 2CRFA 3PG7A 2V76A 4GXBA 4K2PA 2KCJA 3ZVRA 3PVWA 1BTKA 1T77A 3TCAA 2RGNB 2KUPA 3U7DA 2FJLA 2OTXA 2ROZB 2COAA 1GC7A 2YSZA 4DIXA 1E5WA 2J0JA 1Y19B 4QXAB 1KZGA 3SV1A 3OANA 1U5GA 2RLOA 1XR0B 2RSGA 2D9VA 4QJ5B 5I2SA 5C5BB 5DIFB 1FHXA 2YS1A 5CLLB 4HAWB 2HTHB 1MI1A 1DDMA 1TQZA 1KZ7A 3GYPA 4WVFB 3HSAA 5FI0A 3MPXA 4CYEA 2Z0OA 2ELAA 3HQCA 2P0DA 3QBVB 2I5FA 5J3TA 2DLWA 5M4YB 1W1GA 3ML4A 1DYNA 2DHJA 3HW2B 5JHHA 4HB4B 2G35A 4HB2B 2EMSA 1X86A 5HE2A 2YT1A 4BBKA 1J19A 2R0DA 4KAXB 2Y7BA 2Z4DA 4CHMA 2DKPA 3PVLA 1LB1A 2CAYA 3RCPA 3N7CA 2GUMA 1GG3A 5GOWB 3P7ZA 2CY4A 2XQNM 3QWMA 2W2XC 2Z14A 3T06A 1SGHA 5EFXA 4D0NB 2CODA 3G9WA 4ZRKA 2YRYA 3AU5A 4NSWA 2LG1A 1Q67A 3D8DA 1OMWA 1AQCA 2N23A 5C5BA 4Y94A 3TW1A 1TJ6A 3P6AA 3A8PA 2QKMA 2LOZA 3PEGA 2D2QA 2YVCA 5LG4B 2DKQA 2N0YA 4Z2NA 2BCJA 4P7IA 1U5DA 1MAIA 4HSIA 4IOYX 2ZPYA 1K5GB 1NU2A 5D3VA 1FHOA 4PNKA 2COCA 1I7AA 3NW8A 3A8QA 2KIEA 1ZC4B 1GC6A 2VSZA 4HAVB 1XODA 3PVUA 2EMTA 2P0FA 1XKEA 3KRXA 3D8EA 4MT7A 1WJMA 3WYFB 1K5DB 2GS0A 2ROVA 5C6RA 2KUQA 5L81A 3V5WA 1ZC3B 1PMSA 2M38A 2YF0A 3U12A 1RJ2A 5JHGA 1M7EA 3CXBB 5DI9B 5LONB 1EAZA 4YL8A 2YT2A 2Z0PA 1KI1B 3F5RA 4F7UP 2DX1A 5KCVA 3HK0A 2D9WA 5D3WA 1I2HA 1U5EA 4HHVA 1X1GA 3TFMA 4TYZA 4PQ0A 3F0WA 1BTNA 2VRWB 4D6WA 2GCJA 3BINA 4IAPA 1Y5OA 2DFKA 4Z2MB 3IVFA 2YT0A 4GZUA 2I5CA 3O96A 2DX5A 3U8ZA 1LW3A 2PZ1A
chains in the Genus database with same CATH topology
3ODWA 2ADZA 1UPQA 4MY6A 1FOEA 1MK7B 1X1FA 4A6FB 1DBHA 1NTVA 2YS5A 3X23A 1U27A 2MWNB 1MPHA 2D10A 2H7EA 4HAYB 3ODOA 3KRWA 4ZRJA 4DXAB 1P6SA 4WJ7A 1ZSQA 3VOQA 2VKIA 4H8SA 4A6KA 3LJUX 2L1CA 4HB3B 5JP4A 1NTYA 1V5PA 1ZVRA 4EKUA 1BWNA 1UPRA 2AEHA 1OY2A 2CY5A 4GN1A 3DXCA 2Z0QA 5HE1A 3TO1A 3ULCA 3FEHA 3VIAA 1PFJA 5J3YA 4F7GA 1V61A 2Q13A 5FI1A 5LOPB 2LOXA 1MK9B 4HAUB 4GMXB 1DDVA 4ZRIA 1OQNA 5J3QA 2R09A 1V5MA 3DXEA 3UZTA 3ZDTA 4K17A 2RNRB 4EMOA 5CLQB 4L6EA 5C16A 1B55A 1MKEA 1WI1A 1IRSA 4B6HA 4K2OA 5JLJB 1MIXA 3PZDA 2HE7A 2RVBB 4A6FA 2QKLA 4MK0A 2JP2A 2UZSA 2H7DA 1W1DA 2DYQA 2OQBA 4TKNA 1XD4A 3AU4A 2GJYA 1UNQA 2IFSA 4HAXB 4KHBB 1Z87A 4HDQA 2W2WA 5KQ1A 1BAKA 1AWEA 3DXDA 4HB0B 2COFA 2MKRA 1DDWA 2P0HA 4GMVA 2LYDA 3SO6A 2D9ZA 5HE3A 2EC1A 1EVHA 5D3XA 1U2BA 1UNRA 2K00A 3GYOA 1RRPB 1ISNA 4NY0A 2NMBA 4EJNA 1FHWA 2DHKA 3FM8C 3BJIA 4A6HA 2I1JA 2GCLA 1V88A 4KHOA 4DX8A 2Y8GA 5KQ4A 1MIZB 2UVMA 2ELBA 2YS3A 1U5FA 2J59M 1V5UA 4HDOA 5C79A 5D27A 2J0MA 3PSCA 4HAZB 1U29A 2KGXB 1H4RA 1WVHA 2E2XA 2D11A 1UEFA 3M1IB 2NZ8B 3WA0A 2K2UA 5DH9B 2DHIA 1FAOA 1N3HA 3KZ1A 1UNPA 2IYBA 1WGUA 2J0KA 2AL6A 1X05A 4XWXA 1ZM0A 3ULBA 1SHCA 5HE0A 2D9YA 3MDBC 3D8FA 1X11A 4KVGB 3NSUA 4DX90 2MFQA 2EJ8A 2D9XA 3FSSA 1W1HA 1EGXA 1FGYA 2DYNA 2DN6A 4KHAA 1TXDA 4HATB 3ODXA 2M14A 4F7HA 4YONA 3PP2A 5DHFB 1XCGA 4K81A 3KY9A 1NI2A 1P5TA 1J0WA 2K2JA 2L2IA 2LKOA 4WSFA 3SNHA 2RUKB 2UZRA 4DBBA 2X18A 1M7RA 2D4QA 1V89A 1FGZA 2P8VA 2DA0A 3SUZA 2I1KA 3A98B 1EF1A 1WJ1A 2W2XD 1QQGA 1H10A 4C0AA 3CIKA 1DROA 1WG7A 4GPTB 1XX0A 2Y8FA 1PLSA 1WGQA 3KSYA 2DTCA 5DHAB 3QIJA 4CHJA 2LULA 1QC6A 1P3RA 4IFSA 1FB8A 3SYXA 3AJ4A 5D3YA 2MDXA 3TVVA 4A5KA 2CRFA 3PG7A 2V76A 4GXBA 4K2PA 2KCJA 3ZVRA 3PVWA 1BTKA 3TCAA 2RGNB 2KUPA 3U7DA 2FJLA 2OTXA 2ROZB 2COAA 1GC7A 2YSZA 1E5WA 2J0JA 1Y19B 1KZGA 3SV1A 3OANA 1U5GA 2RLOA 1XR0B 2RSGA 2D9VA 5C5BB 5DIFB 1FHXA 2YS1A 5CLLB 4HAWB 2HTHB 1DDMA 1TQZA 1KZ7A 3GYPA 4WVFB 5FI0A 3MPXA 4CYEA 2Z0OA 2ELAA 3HQCA 2P0DA 3QBVB 2I5FA 5J3TA 2DLWA 1W1GA 3ML4A 1DYNA 2DHJA 3HW2B 5JHHA 4HB4B 2G35A 4HB2B 2EMSA 1X86A 5HE2A 2YT1A 4BBKA 1J19A 2R0DA 4KAXB 2Y7BA 4CHMA 2DKPA 3PVLA 1LB1A 2CAYA 3RCPA 3N7CA 1GG3A 5GOWB 3P7ZA 2CY4A 2XQNM 3QWMA 2W2XC 3T06A 1SGHA 5EFXA 4D0NB 2CODA 3G9WA 4ZRKA 2YRYA 3AU5A 4NSWA 2LG1A 1Q67A 3D8DA 1OMWA 1AQCA 2N23A 5C5BA 4Y94A 3TW1A 1TJ6A 3P6AA 3A8PA 2QKMA 2LOZA 3PEGA 2D2QA 2YVCA 2DKQA 2N0YA 4Z2NA 2BCJA 4P7IA 1U5DA 1MAIA 4IOYX 2ZPYA 1K5GB 1NU2A 5D3VA 1FHOA 4PNKA 2COCA 1I7AA 3A8QA 1ZC4B 1GC6A 2VSZA 4HAVB 1XODA 3PVUA 2EMTA 2P0FA 1XKEA 3KRXA 3D8EA 4MT7A 1WJMA 3WYFB 1K5DB 2GS0A 2ROVA 5C6RA 5L81A 3V5WA 1ZC3B 1PMSA 2M38A 2YF0A 1RJ2A 5JHGA 1M7EA 3CXBB 5DI9B 5LONB 1EAZA 4YL8A 2Z0PA 1KI1B 3F5RA 4F7UP 2DX1A 5KCVA 3HK0A 2D9WA 5D3WA 1I2HA 1U5EA 4HHVA 1X1GA 3TFMA 4TYZA 4PQ0A 3F0WA 1BTNA 2VRWB 2GCJA 3BINA 4IAPA 1Y5OA 2DFKA 4Z2MB 3IVFA 2YT0A 4GZUA 2I5CA 3O96A 2DX5A 3U8ZA 1LW3A 2PZ1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ODW A;  2ADZ A;  1UPQ A;  4MY6 A;  1FOE A;  1MK7 B;  1X1F A;  4A6F B;  1DBH A;  1NTV A;  2YS5 A;  3X23 A;  1U27 A;  2MWN B;  1MPH A;  2D10 A;  2H7E A;  4HAY B;  3ODO A;  3KRW A;  4ZRJ A;  4DXA B;  1P6S A;  4WJ7 A;  1ZSQ A;  3VOQ A;  2VKI A;  4H8S A;  4A6K A;  3LJU X;  2L1C A;  4HB3 B;  5JP4 A;  1NTY A;  1V5P A;  1ZVR A;  4EKU A;  1BWN A;  1UPR A;  2AEH A;  1OY2 A;  2CY5 A;  4GN1 A;  3DXC A;  2Z0Q A;  5HE1 A;  3TO1 A;  3ULC A;  3FEH A;  3VIA A;  1PFJ A;  5J3Y A;  4F7G A;  1V61 A;  2Q13 A;  5FI1 A;  5LOP B;  2LOX A;  1MK9 B;  4HAU B;  4GMX B;  1DDV A;  4ZRI A;  1OQN A;  5J3Q A;  2R09 A;  1V5M A;  3DXE A;  3UZT A;  3ZDT A;  4K17 A;  2RNR B;  4EMO A;  5CLQ B;  4L6E A;  5C16 A;  1B55 A;  1MKE A;  1WI1 A;  1IRS A;  4B6H A;  4K2O A;  5JLJ B;  1MIX A;  3PZD A;  2HE7 A;  2RVB B;  4A6F A;  2QKL A;  4MK0 A;  2JP2 A;  2UZS A;  2H7D A;  1W1D A;  2DYQ A;  2OQB A;  4TKN A;  1XD4 A;  3AU4 A;  2GJY A;  1UNQ A;  2IFS A;  4HAX B;  4KHB B;  1Z87 A;  4HDQ A;  2W2W A;  5KQ1 A;  1BAK A;  1AWE A;  3DXD A;  4HB0 B;  2COF A;  2MKR A;  1DDW A;  2P0H A;  4GMV A;  2LYD A;  3SO6 A;  2D9Z A;  5HE3 A;  2EC1 A;  1EVH A;  5D3X A;  1U2B A;  1UNR A;  2K00 A;  3GYO A;  1RRP B;  1ISN A;  4NY0 A;  2NMB A;  4EJN A;  1FHW A;  2DHK A;  3FM8 C;  3BJI A;  4A6H A;  2I1J A;  2GCL A;  1V88 A;  4KHO A;  4DX8 A;  2Y8G A;  5KQ4 A;  1MIZ B;  2UVM A;  2ELB A;  2YS3 A;  1U5F A;  2J59 M;  1V5U A;  4HDO A;  5C79 A;  5D27 A;  2J0M A;  3PSC A;  4HAZ B;  1U29 A;  2KGX B;  1H4R A;  1WVH A;  2E2X A;  2D11 A;  1UEF A;  3M1I B;  2NZ8 B;  3WA0 A;  2K2U A;  5DH9 B;  2DHI A;  1FAO A;  1N3H A;  3KZ1 A;  1UNP A;  2IYB A;  1WGU A;  2J0K A;  2AL6 A;  1X05 A;  4XWX A;  1ZM0 A;  3ULB A;  1SHC A;  5HE0 A;  2D9Y A;  3MDB C;  3D8F A;  1X11 A;  4KVG B;  3NSU A;  4DX9 0;  2MFQ A;  2EJ8 A;  2D9X A;  3FSS A;  1W1H A;  1EGX A;  1FGY A;  2DYN A;  2DN6 A;  4KHA A;  1TXD A;  4HAT B;  3ODX A;  2M14 A;  4F7H A;  4YON A;  3PP2 A;  5DHF B;  1XCG A;  4K81 A;  3KY9 A;  1NI2 A;  1P5T A;  1J0W A;  2K2J A;  2L2I A;  2LKO A;  4WSF A;  3SNH A;  2RUK B;  2UZR A;  4DBB A;  2X18 A;  1M7R A;  2D4Q A;  1V89 A;  1FGZ A;  2P8V A;  2DA0 A;  3SUZ A;  2I1K A;  3A98 B;  1EF1 A;  1WJ1 A;  2W2X D;  1QQG A;  1H10 A;  4C0A A;  3CIK A;  1DRO A;  1WG7 A;  4GPT B;  1XX0 A;  2Y8F A;  1PLS A;  1WGQ A;  3KSY A;  2DTC A;  5DHA B;  3QIJ A;  4CHJ A;  2LUL A;  1QC6 A;  1P3R A;  4IFS A;  1FB8 A;  3SYX A;  3AJ4 A;  5D3Y A;  2MDX A;  3TVV A;  4A5K A;  2CRF A;  3PG7 A;  2V76 A;  4GXB A;  4K2P A;  2KCJ A;  3ZVR A;  3PVW A;  1BTK A;  3TCA A;  2RGN B;  2KUP A;  3U7D A;  2FJL A;  2OTX A;  2ROZ B;  2COA A;  1GC7 A;  2YSZ A;  1E5W A;  2J0J A;  1Y19 B;  1KZG A;  3SV1 A;  3OAN A;  1U5G A;  2RLO A;  1XR0 B;  2RSG A;  2D9V A;  5C5B B;  5DIF B;  1FHX A;  2YS1 A;  5CLL B;  4HAW B;  2HTH B;  1DDM A;  1TQZ A;  1KZ7 A;  3GYP A;  4WVF B;  5FI0 A;  3MPX A;  4CYE A;  2Z0O A;  2ELA A;  3HQC A;  2P0D A;  3QBV B;  2I5F A;  5J3T A;  2DLW A;  1W1G A;  3ML4 A;  1DYN A;  2DHJ A;  3HW2 B;  5JHH A;  4HB4 B;  2G35 A;  4HB2 B;  2EMS A;  1X86 A;  5HE2 A;  2YT1 A;  4BBK A;  1J19 A;  2R0D A;  4KAX B;  2Y7B A;  4CHM A;  2DKP A;  3PVL A;  1LB1 A;  2CAY A;  3RCP A;  3N7C A;  1GG3 A;  5GOW B;  3P7Z A;  2CY4 A;  2XQN M;  3QWM A;  2W2X C;  3T06 A;  1SGH A;  5EFX A;  4D0N B;  2COD A;  3G9W A;  4ZRK A;  2YRY A;  3AU5 A;  4NSW A;  2LG1 A;  1Q67 A;  3D8D A;  1OMW A;  1AQC A;  2N23 A;  5C5B A;  4Y94 A;  3TW1 A;  1TJ6 A;  3P6A A;  3A8P A;  2QKM A;  2LOZ A;  3PEG A;  2D2Q A;  2YVC A;  2DKQ A;  2N0Y A;  4Z2N A;  2BCJ A;  4P7I A;  1U5D A;  1MAI A;  4IOY X;  2ZPY A;  1K5G B;  1NU2 A;  5D3V A;  1FHO A;  4PNK A;  2COC A;  1I7A A;  3A8Q A;  1ZC4 B;  1GC6 A;  2VSZ A;  4HAV B;  1XOD A;  3PVU A;  2EMT A;  2P0F A;  1XKE A;  3KRX A;  3D8E A;  4MT7 A;  1WJM A;  3WYF B;  1K5D B;  2GS0 A;  2ROV A;  5C6R A;  5L81 A;  3V5W A;  1ZC3 B;  1PMS A;  2M38 A;  2YF0 A;  1RJ2 A;  5JHG A;  1M7E A;  3CXB B;  5DI9 B;  5LON B;  1EAZ A;  4YL8 A;  2Z0P A;  1KI1 B;  3F5R A;  4F7U P;  2DX1 A;  5KCV A;  3HK0 A;  2D9W A;  5D3W A;  1I2H A;  1U5E A;  4HHV A;  1X1G A;  3TFM A;  4TYZ A;  4PQ0 A;  3F0W A;  1BTN A;  2VRW B;  2GCJ A;  3BIN A;  4IAP A;  1Y5O A;  2DFK A;  4Z2M B;  3IVF A;  2YT0 A;  4GZU A;  2I5C A;  3O96 A;  2DX5 A;  3U8Z A;  1LW3 A;  2PZ1 A; 
#chains in the Genus database with same CATH topology
 3ODW A;  2ADZ A;  1UPQ A;  4MY6 A;  1FOE A;  1MK7 B;  1X1F A;  4A6F B;  1DBH A;  1NTV A;  2YS5 A;  3X23 A;  1U27 A;  2MWN B;  1MPH A;  2D10 A;  2H7E A;  4HAY B;  3ODO A;  3KRW A;  4ZRJ A;  4DXA B;  1P6S A;  4WJ7 A;  1ZSQ A;  3A58 A;  3VOQ A;  2VKI A;  4H8S A;  4A6K A;  3LJU X;  2L1C A;  4OT1 A;  2K8E A;  4HB3 B;  5JP4 A;  1NTY A;  1V5P A;  1ZVR A;  4EKU A;  1BWN A;  1UPR A;  2AEH A;  1OY2 A;  1ZYI A;  2CY5 A;  4GN1 A;  3DXC A;  2Z0Q A;  5HE1 A;  3TO1 A;  3ULC A;  3FEH A;  3VIA A;  1PFJ A;  5J3Y A;  4F7G A;  1V61 A;  2Q13 A;  5FI1 A;  5LOP B;  2LOX A;  1MK9 B;  4HAU B;  4GMX B;  1DDV A;  4ZRI A;  1OQN A;  3DCX A;  4QJ3 B;  5J3Q A;  2R09 A;  2R2Y A;  1V5M A;  2RRF A;  3DXE A;  3UZT A;  3ZDT A;  4K17 A;  2RNR B;  4EMO A;  5CLQ B;  4L6E A;  5C16 A;  1B55 A;  1MKE A;  1WI1 A;  1IRS A;  4B6H A;  4K2O A;  5JLJ B;  1MIX A;  4GNK B;  3PZD A;  2HE7 A;  2RVB B;  4A6F A;  2QKL A;  4MK0 A;  2JP2 A;  2UZS A;  2H7D A;  1W1D A;  2DYQ A;  2OQB A;  3NWF A;  4TKN A;  1XD4 A;  3NWD A;  2Z13 A;  2GJY A;  1UNQ A;  3AU4 A;  2IFS A;  4HAX B;  4KHB B;  1Z87 A;  4HDQ A;  2W2W A;  5KQ1 A;  1BAK A;  2KR0 A;  1AWE A;  3DXD A;  4HB0 B;  2COF A;  2MKR A;  1DDW A;  2P0H A;  3HIE A;  4GMV A;  2LYD A;  3SO6 A;  2D9Z A;  5HE3 A;  2EC1 A;  5I2M A;  1EVH A;  5D3X A;  1U2B A;  1UNR A;  2K00 A;  3GYO A;  1RRP B;  1ISN A;  4NY0 A;  2NMB A;  4EJN A;  1FHW A;  2DHK A;  3FM8 C;  3BJI A;  3B77 A;  4A6H A;  2I1J A;  2GCL A;  1V88 A;  4KHO A;  4DX8 A;  2Y8G A;  5KQ4 A;  1MIZ B;  2UVM A;  2ELB A;  2YS3 A;  1U5F A;  2J59 M;  1V5U A;  2NBV A;  4HDO A;  5C79 A;  5D27 A;  2J0M A;  3PSC A;  4HAZ B;  4CSQ A;  1U29 A;  2KGX B;  1H4R A;  1WVH A;  2E2X A;  2D11 A;  1UEF A;  3M1I B;  3FVC A;  2NZ8 B;  3WA0 A;  2K2U A;  5DH9 B;  2DHI A;  1FAO A;  1N3H A;  3KZ1 A;  2ZKM X;  1UNP A;  5IRS A;  2IYB A;  1WGU A;  2J0K A;  2AL6 A;  1X05 A;  4XWX A;  1ZM0 A;  3ULB A;  4KHB A;  1SHC A;  5HE0 A;  2D9Y A;  3MDB C;  4L1R A;  3D8F A;  1X11 A;  4KVG B;  3NSU A;  4DX9 0;  2MFQ A;  2EJ8 A;  2D9X A;  3FSS A;  1W1H A;  3NWA A;  1EGX A;  1FGY A;  2DYN A;  2DN6 A;  4KHA A;  1TXD A;  4HAT B;  3ODX A;  2M14 A;  4F7H A;  4QJ4 B;  4YON A;  3PP2 A;  5DHF B;  1XCG A;  4K81 A;  2KIG A;  1NI2 A;  1P5T A;  1J0W A;  2K2J A;  2LKO A;  2L2I A;  3KY9 A;  4WSF A;  3SNH A;  2RUK B;  2UZR A;  4DBB A;  2X18 A;  1M7R A;  2Z59 A;  2D4Q A;  1V89 A;  1FGZ A;  2P8V A;  2DA0 A;  3SUZ A;  2I1K A;  4OSN A;  3A98 B;  1EF1 A;  1WJ1 A;  4GOU A;  2W2X D;  1QQG A;  1H10 A;  2K49 A;  4C0A A;  3CIK A;  1DRO A;  1WG7 A;  4GPT B;  1XX0 A;  2Y8F A;  1PLS A;  1WGQ A;  3KSY A;  2DTC A;  5DHA B;  3QIJ A;  4CHJ A;  2LUL A;  1QC6 A;  3OHM B;  1P3R A;  4IFS A;  1FB8 A;  3SYX A;  3AJ4 A;  5D3Y A;  2MDX A;  2FJU B;  3TVV A;  4A5K A;  2CRF A;  3PG7 A;  2V76 A;  4GXB A;  4K2P A;  2KCJ A;  3ZVR A;  3PVW A;  1BTK A;  1T77 A;  3TCA A;  2RGN B;  2KUP A;  3U7D A;  2FJL A;  2OTX A;  2ROZ B;  2COA A;  1GC7 A;  2YSZ A;  4DIX A;  1E5W A;  2J0J A;  1Y19 B;  4QXA B;  1KZG A;  3SV1 A;  3OAN A;  1U5G A;  2RLO A;  1XR0 B;  2RSG A;  2D9V A;  4QJ5 B;  5I2S A;  5C5B B;  5DIF B;  1FHX A;  2YS1 A;  5CLL B;  4HAW B;  2HTH B;  1MI1 A;  1DDM A;  1TQZ A;  1KZ7 A;  3GYP A;  4WVF B;  3HSA A;  5FI0 A;  3MPX A;  4CYE A;  2Z0O A;  2ELA A;  3HQC A;  2P0D A;  3QBV B;  2I5F A;  5J3T A;  2DLW A;  5M4Y B;  1W1G A;  3ML4 A;  1DYN A;  2DHJ A;  3HW2 B;  5JHH A;  4HB4 B;  2G35 A;  4HB2 B;  2EMS A;  1X86 A;  5HE2 A;  2YT1 A;  4BBK A;  1J19 A;  2R0D A;  4KAX B;  2Y7B A;  2Z4D A;  4CHM A;  2DKP A;  3PVL A;  1LB1 A;  2CAY A;  3RCP A;  3N7C A;  2GUM A;  1GG3 A;  5GOW B;  3P7Z A;  2CY4 A;  2XQN M;  3QWM A;  2W2X C;  2Z14 A;  3T06 A;  1SGH A;  5EFX A;  4D0N B;  2COD A;  3G9W A;  4ZRK A;  2YRY A;  3AU5 A;  4NSW A;  2LG1 A;  1Q67 A;  3D8D A;  1OMW A;  1AQC A;  2N23 A;  5C5B A;  4Y94 A;  3TW1 A;  1TJ6 A;  3P6A A;  3A8P A;  2QKM A;  2LOZ A;  3PEG A;  2D2Q A;  2YVC A;  5LG4 B;  2DKQ A;  2N0Y A;  4Z2N A;  2BCJ A;  4P7I A;  1U5D A;  1MAI A;  4HSI A;  4IOY X;  2ZPY A;  1K5G B;  1NU2 A;  5D3V A;  1FHO A;  4PNK A;  2COC A;  1I7A A;  3NW8 A;  3A8Q A;  2KIE A;  1ZC4 B;  1GC6 A;  2VSZ A;  4HAV B;  1XOD A;  3PVU A;  2EMT A;  2P0F A;  1XKE A;  3KRX A;  3D8E A;  4MT7 A;  1WJM A;  3WYF B;  1K5D B;  2GS0 A;  2ROV A;  5C6R A;  2KUQ A;  5L81 A;  3V5W A;  1ZC3 B;  1PMS A;  2M38 A;  2YF0 A;  3U12 A;  1RJ2 A;  5JHG A;  1M7E A;  3CXB B;  5DI9 B;  5LON B;  1EAZ A;  4YL8 A;  2YT2 A;  2Z0P A;  1KI1 B;  3F5R A;  4F7U P;  2DX1 A;  5KCV A;  3HK0 A;  2D9W A;  5D3W A;  1I2H A;  1U5E A;  4HHV A;  1X1G A;  3TFM A;  4TYZ A;  4PQ0 A;  3F0W A;  1BTN A;  2VRW B;  4D6W A;  2GCJ A;  3BIN A;  4IAP A;  1Y5O A;  2DFK A;  4Z2M B;  3IVF A;  2YT0 A;  4GZU A;  2I5C A;  3O96 A;  2DX5 A;  3U8Z A;  1LW3 A;  2PZ1 A; 
#chains in the Genus database with same CATH homology
 3ODW A;  2ADZ A;  1UPQ A;  4MY6 A;  1FOE A;  1MK7 B;  1X1F A;  4A6F B;  1DBH A;  1NTV A;  2YS5 A;  3X23 A;  1U27 A;  2MWN B;  1MPH A;  2D10 A;  2H7E A;  4HAY B;  3ODO A;  3KRW A;  4ZRJ A;  4DXA B;  1P6S A;  4WJ7 A;  1ZSQ A;  3VOQ A;  2VKI A;  4H8S A;  4A6K A;  3LJU X;  2L1C A;  4HB3 B;  5JP4 A;  1NTY A;  1V5P A;  1ZVR A;  4EKU A;  1BWN A;  1UPR A;  2AEH A;  1OY2 A;  2CY5 A;  4GN1 A;  3DXC A;  2Z0Q A;  5HE1 A;  3TO1 A;  3ULC A;  3FEH A;  3VIA A;  1PFJ A;  5J3Y A;  4F7G A;  1V61 A;  2Q13 A;  5FI1 A;  5LOP B;  2LOX A;  1MK9 B;  4HAU B;  4GMX B;  1DDV A;  4ZRI A;  1OQN A;  5J3Q A;  2R09 A;  1V5M A;  3DXE A;  3UZT A;  3ZDT A;  4K17 A;  2RNR B;  4EMO A;  5CLQ B;  4L6E A;  5C16 A;  1B55 A;  1MKE A;  1WI1 A;  1IRS A;  4B6H A;  4K2O A;  5JLJ B;  1MIX A;  3PZD A;  2HE7 A;  2RVB B;  4A6F A;  2QKL A;  4MK0 A;  2JP2 A;  2UZS A;  2H7D A;  1W1D A;  2DYQ A;  2OQB A;  4TKN A;  1XD4 A;  3AU4 A;  2GJY A;  1UNQ A;  2IFS A;  4HAX B;  4KHB B;  1Z87 A;  4HDQ A;  2W2W A;  5KQ1 A;  1BAK A;  1AWE A;  3DXD A;  4HB0 B;  2COF A;  2MKR A;  1DDW A;  2P0H A;  4GMV A;  2LYD A;  3SO6 A;  2D9Z A;  5HE3 A;  2EC1 A;  1EVH A;  5D3X A;  1U2B A;  1UNR A;  2K00 A;  3GYO A;  1RRP B;  1ISN A;  4NY0 A;  2NMB A;  4EJN A;  1FHW A;  2DHK A;  3FM8 C;  3BJI A;  4A6H A;  2I1J A;  2GCL A;  1V88 A;  4KHO A;  4DX8 A;  2Y8G A;  5KQ4 A;  1MIZ B;  2UVM A;  2ELB A;  2YS3 A;  1U5F A;  2J59 M;  1V5U A;  4HDO A;  5C79 A;  5D27 A;  2J0M A;  3PSC A;  4HAZ B;  1U29 A;  2KGX B;  1H4R A;  1WVH A;  2E2X A;  2D11 A;  1UEF A;  3M1I B;  2NZ8 B;  3WA0 A;  2K2U A;  5DH9 B;  2DHI A;  1FAO A;  1N3H A;  3KZ1 A;  1UNP A;  2IYB A;  1WGU A;  2J0K A;  2AL6 A;  1X05 A;  4XWX A;  1ZM0 A;  3ULB A;  1SHC A;  5HE0 A;  2D9Y A;  3MDB C;  3D8F A;  1X11 A;  4KVG B;  3NSU A;  4DX9 0;  2MFQ A;  2EJ8 A;  2D9X A;  3FSS A;  1W1H A;  1EGX A;  1FGY A;  2DYN A;  2DN6 A;  4KHA A;  1TXD A;  4HAT B;  3ODX A;  2M14 A;  4F7H A;  4YON A;  3PP2 A;  5DHF B;  1XCG A;  4K81 A;  3KY9 A;  1NI2 A;  1P5T A;  1J0W A;  2K2J A;  2L2I A;  2LKO A;  4WSF A;  3SNH A;  2RUK B;  2UZR A;  4DBB A;  2X18 A;  1M7R A;  2D4Q A;  1V89 A;  1FGZ A;  2P8V A;  2DA0 A;  3SUZ A;  2I1K A;  3A98 B;  1EF1 A;  1WJ1 A;  2W2X D;  1QQG A;  1H10 A;  4C0A A;  3CIK A;  1DRO A;  1WG7 A;  4GPT B;  1XX0 A;  2Y8F A;  1PLS A;  1WGQ A;  3KSY A;  2DTC A;  5DHA B;  3QIJ A;  4CHJ A;  2LUL A;  1QC6 A;  1P3R A;  4IFS A;  1FB8 A;  3SYX A;  3AJ4 A;  5D3Y A;  2MDX A;  3TVV A;  4A5K A;  2CRF A;  3PG7 A;  2V76 A;  4GXB A;  4K2P A;  2KCJ A;  3ZVR A;  3PVW A;  1BTK A;  3TCA A;  2RGN B;  2KUP A;  3U7D A;  2FJL A;  2OTX A;  2ROZ B;  2COA A;  1GC7 A;  2YSZ A;  1E5W A;  2J0J A;  1Y19 B;  1KZG A;  3SV1 A;  3OAN A;  1U5G A;  2RLO A;  1XR0 B;  2RSG A;  2D9V A;  5C5B B;  5DIF B;  1FHX A;  2YS1 A;  5CLL B;  4HAW B;  2HTH B;  1DDM A;  1TQZ A;  1KZ7 A;  3GYP A;  4WVF B;  5FI0 A;  3MPX A;  4CYE A;  2Z0O A;  2ELA A;  3HQC A;  2P0D A;  3QBV B;  2I5F A;  5J3T A;  2DLW A;  1W1G A;  3ML4 A;  1DYN A;  2DHJ A;  3HW2 B;  5JHH A;  4HB4 B;  2G35 A;  4HB2 B;  2EMS A;  1X86 A;  5HE2 A;  2YT1 A;  4BBK A;  1J19 A;  2R0D A;  4KAX B;  2Y7B A;  4CHM A;  2DKP A;  3PVL A;  1LB1 A;  2CAY A;  3RCP A;  3N7C A;  1GG3 A;  5GOW B;  3P7Z A;  2CY4 A;  2XQN M;  3QWM A;  2W2X C;  3T06 A;  1SGH A;  5EFX A;  4D0N B;  2COD A;  3G9W A;  4ZRK A;  2YRY A;  3AU5 A;  4NSW A;  2LG1 A;  1Q67 A;  3D8D A;  1OMW A;  1AQC A;  2N23 A;  5C5B A;  4Y94 A;  3TW1 A;  1TJ6 A;  3P6A A;  3A8P A;  2QKM A;  2LOZ A;  3PEG A;  2D2Q A;  2YVC A;  2DKQ A;  2N0Y A;  4Z2N A;  2BCJ A;  4P7I A;  1U5D A;  1MAI A;  4IOY X;  2ZPY A;  1K5G B;  1NU2 A;  5D3V A;  1FHO A;  4PNK A;  2COC A;  1I7A A;  3A8Q A;  1ZC4 B;  1GC6 A;  2VSZ A;  4HAV B;  1XOD A;  3PVU A;  2EMT A;  2P0F A;  1XKE A;  3KRX A;  3D8E A;  4MT7 A;  1WJM A;  3WYF B;  1K5D B;  2GS0 A;  2ROV A;  5C6R A;  5L81 A;  3V5W A;  1ZC3 B;  1PMS A;  2M38 A;  2YF0 A;  1RJ2 A;  5JHG A;  1M7E A;  3CXB B;  5DI9 B;  5LON B;  1EAZ A;  4YL8 A;  2Z0P A;  1KI1 B;  3F5R A;  4F7U P;  2DX1 A;  5KCV A;  3HK0 A;  2D9W A;  5D3W A;  1I2H A;  1U5E A;  4HHV A;  1X1G A;  3TFM A;  4TYZ A;  4PQ0 A;  3F0W A;  1BTN A;  2VRW B;  2GCJ A;  3BIN A;  4IAP A;  1Y5O A;  2DFK A;  4Z2M B;  3IVF A;  2YT0 A;  4GZU A;  2I5C A;  3O96 A;  2DX5 A;  3U8Z A;  1LW3 A;  2PZ1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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