5D27A

Crystal structure of the p-rex1 ph domain
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
166
structure length
154
Chain Sequence
GEFEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKSKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKLGMERDAYV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac excha
publication title Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Lipid binding protein
total genus 45
structure length 154
sequence length 166
ec nomenclature
pdb deposition date 2015-08-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 5d27A00
3FM8C 1BTKA 2M14A 3A8QA 2M38A 2I1KA 1WG7A 2QKMA 4HAXB 2Z0PA 4HDQA 1EVHA 2BCJA 2H7DA 4GMXB 3PVUA 1X11A 1W1GA 3X23A 1ZM0A 5J3YA 1DDMA 5D27A 3V5WA 2AL6A 4WVFB 5LONB 2D2QA 3VOQA 3D8EA 1FHWA 5C5BA 1DDWA 2ADZA 2DX1A 1V5PA 5D3WA 2HE7A 2J59M 4K2OA 2DFKA 2L1CA 4ZRKA 3AU5A 1FOEA 1UPQA 2DHJA 2P0DA 1BWNA 1PFJA 4YONA 2P0HA 4HB0B 3ODXA 2ROZB 1MKEA 1P6SA 2DKQA 1WGUA 2KGXB 2V76A 2YS5A 1EGXA 5JLJB 3AU4A 1U5GA 2D4QA 2IFSA 1V5MA 4KHOA 1FHOA 3SO6A 3O96A 1M7EA 2JP2A 4BBKA 1DBHA 2EMTA 2D9XA 1IRSA 4A6KA 2GCJA 4ZRIA 1XR0B 1H4RA 2X18A 4GPTB 3A98B 5FI1A 4KVGB 4K2PA 1FGYA 5DHAB 3N7CA 3HW2B 3ZDTA 4NY0A 2COAA 2YF0A 5C16A 3TVVA 4GN1A 5C79A 1V5UA 4DX8A 4PNKA 1DROA 1PMSA 3QIJA 2J0MA 4B6HA 4KHAA 1I7AA 2R0DA 2W2XC 1P3RA 1K5DB 1KZGA 3SUZA 4HB4B 2YSZA 3DXEA 3M1IB 4GZUA 2YRYA 1LW3A 1MIZB 1MK7B 2IYBA 4PQ0A 2W2WA 1FB8A 4ZRJA 2I1JA 2LOZA 4A6HA 3ZVRA 4K81A 2CY4A 1UNPA 1J19A 4EMOA 4MK0A 1XKEA 1B55A 2P8VA 1V89A 2D9WA 5HE2A 2LOXA 3G9WA 1NTVA 3FSSA 3P6AA 3PSCA 1TXDA 1WVHA 3D8DA 1Y19B 3PG7A 2N23A 4HAYB 4Z2MB 2W2XD 1TJ6A 1Y5OA 1AWEA 3GYPA 4HAWB 1J0WA 5D3VA 4CHMA 4A5KA 2DYNA 5DI9B 2RLOA 3KRWA 3BJIA 4DXAB 5C6RA 2YT0A 4WJ7A 5KQ4A 2NZ8B 4GMVA 1UNQA 2LG1A 5C5BB 1RRPB 1DDVA 2G35A 5CLLB 4NSWA 2RGNB 1FAOA 5KQ1A 3QWMA 1M7RA 3ULCA 4C0AA 2K2UA 4DX90 5DHFB 4GXBA 2CODA 3QBVB 2EMSA 2I5FA 2AEHA 3ODOA 2COCA 1K5GB 3PVLA 1WGQA 3DXDA 3ULBA 5EFXA 1EAZA 4CHJA 4DBBA 2DHIA 2D9VA 2DKPA 4IOYX 4K17A 2D10A 1XODA 2CRFA 1U29A 3RCPA 4A6FA 2DHKA 1KZ7A 1XD4A 1MAIA 4TYZA 2ROVA 4HHVA 1FGZA 2PZ1A 5HE1A 4KAXB 1U5EA 4HB2B 3DXCA 1X1GA 4F7GA 1QC6A 2Z0QA 1BAKA 3IVFA 4HAZB 5LOPB 2H7EA 2D9YA 2FJLA 3AJ4A 1BTNA 1SGHA 4A6FB 1W1DA 3WYFB 2OTXA 3CIKA 4WSFA 5J3QA 4MT7A 1U5FA 3A8PA 4HDOA 2DX5A 1ZC3B 1P5TA 2RUKB 4P7IA 1QQGA 5HE0A 1U2BA 3SNHA 2Q13A 4F7UP 2LYDA 1RJ2A 3MPXA 4Y94A 2DN6A 2GS0A 3GYOA 3U8ZA 1LB1A 2RNRB 2UZSA 5J3TA 1SHCA 4HAUB 1GC6A 1OY2A 4XWXA 1GC7A 2ELBA 5JP4A 1NU2A 3U7DA 1E5WA 1UPRA 3TO1A 4H8SA 2P0FA 5L81A 3ML4A 1MPHA 1PLSA 2XQNM 4EKUA 3HQCA 1WJMA 5GOWB 3T06A 4KHBB 2VKIA 3D8FA 4F7HA 5JHGA 2K00A 2VSZA 3TFMA 3ODWA 3BINA 5CLQB 3PVWA 2CAYA 4EJNA 2MFQA 2VRWB 1FHXA 1W1HA 3NSUA 3TW1A 3KSYA 2ELAA 3WA0A 1X05A 1MIXA 2Y8FA 2UVMA 3UZTA 1TQZA 5JHHA 2KCJA 1DYNA 3KZ1A 4HB3B 2NMBA 1X1FA 1ZSQA 1XCGA 3VIAA 1N3HA 2GCLA 3HK0A 1EF1A 2E2XA 1ISNA 1WJ1A 4MY6A 2YVCA 4CYEA 3KY9A 3CXBB 4D0NB 5FI0A 2HTHB 5D3XA 3MDBC 1OQNA 1AQCA 4IFSA 3TCAA 1ZC4B 4TKNA 2EC1A 2K2JA 5DH9B 2EJ8A 3LJUX 1NTYA 2CY5A 4Z2NA 1Q67A 2COFA 2QKLA 2DA0A 2OQBA 2N0YA 2YS3A 3SYXA 3SV1A 4IAPA 4YL8A 2Y8GA 5D3YA 3F0WA 3OANA 2ZPYA 2DYQA 2L2IA 1X86A 5DIFB 3F5RA 2MKRA 1U5DA 1UEFA 2I5CA 2J0JA 2YS1A 1Z87A 4L6EA 2DLWA 1MK9B 2GJYA 1H10A 1XX0A 2Z0OA 1NI2A 3PP2A 2KUPA 3FEHA 1KI1B 2UZRA 2MWNB 1WI1A 2LULA 2MDXA 3PEGA 2Y7BA 2LKOA 1GG3A 5KCVA 2D11A 2R09A 1ZVRA 2DTCA 1UNRA 3P7ZA 1U27A 5HE3A 1I2HA 1V61A 2RVBB 3KRXA 1OMWA 2YT1A 2D9ZA 4HAVB 2J0KA 2RSGA 4HATB 3PZDA 1V88A
chains in the Genus database with same CATH superfamily
3FM8C 2KUQA 1BTKA 2M14A 3A8QA 2M38A 2I1KA 1WG7A 2QKMA 4HAXB 2Z0PA 4HDQA 1EVHA 2BCJA 2H7DA 4GMXB 3DCXA 3PVUA 1X11A 1W1GA 3X23A 1ZM0A 5J3YA 1DDMA 5D27A 3V5WA 2AL6A 4WVFB 5LONB 2D2QA 3VOQA 3D8EA 1FHWA 2KR0A 5C5BA 1DDWA 2ADZA 2DX1A 1V5PA 5D3WA 2HE7A 3NWDA 2J59M 4K2OA 2DFKA 2L1CA 4ZRKA 3AU5A 1FOEA 1UPQA 2DHJA 2R2YA 2P0DA 1BWNA 2Z14A 1PFJA 4YONA 2P0HA 4HB0B 2ZKMX 3ODXA 2ROZB 1MKEA 1P6SA 2DKQA 1WGUA 2KGXB 2V76A 2YS5A 1EGXA 5JLJB 3AU4A 1U5GA 2FJUB 1MI1A 2D4QA 2IFSA 1V5MA 4KHOA 1FHOA 3SO6A 3O96A 1M7EA 2JP2A 2Z13A 4BBKA 1DBHA 2EMTA 2D9XA 3A58A 1IRSA 4A6KA 2GCJA 4ZRIA 1XR0B 2KIEA 1H4RA 2Z4DA 4QJ4B 4L1RA 2X18A 4GPTB 3A98B 5FI1A 4KVGB 4K2PA 1FGYA 5DHAB 3N7CA 3HW2B 3ZDTA 4NY0A 2COAA 2YF0A 5C16A 4QXAB 3TVVA 4GN1A 4D6WA 5C79A 1V5UA 4DX8A 4PNKA 1DROA 1PMSA 3QIJA 2J0MA 4B6HA 4KHAA 1I7AA 2R0DA 2W2XC 1P3RA 1K5DB 1KZGA 3SUZA 4HB4B 2YSZA 3DXEA 3M1IB 4GZUA 2YRYA 1LW3A 1MIZB 4KHBA 1MK7B 4OSNA 2IYBA 4PQ0A 2W2WA 1FB8A 4ZRJA 2I1JA 2LOZA 4A6HA 5I2SA 5I2MA 3ZVRA 4K81A 2CY4A 1UNPA 4HSIA 1J19A 4EMOA 4MK0A 5M4YB 1XKEA 1B55A 2P8VA 1V89A 2D9WA 5HE2A 2LOXA 3G9WA 1NTVA 3FSSA 3P6AA 3PSCA 1TXDA 1WVHA 3D8DA 1Y19B 3PG7A 2N23A 4HAYB 4Z2MB 2W2XD 1TJ6A 1Y5OA 2YT2A 3NWAA 1AWEA 3GYPA 4HAWB 1J0WA 5D3VA 4GNKB 4CHMA 4CSQA 4A5KA 4QJ5B 2DYNA 5DI9B 2RLOA 5IRSA 2Z59A 3KRWA 3BJIA 4DXAB 5C6RA 2YT0A 4WJ7A 5KQ4A 2NZ8B 4GMVA 3B77A 1UNQA 2GUMA 2LG1A 3U12A 5C5BB 1RRPB 1DDVA 2G35A 5CLLB 4NSWA 2RGNB 1FAOA 5KQ1A 3QWMA 1M7RA 3ULCA 4C0AA 2K2UA 4DX90 5DHFB 4GXBA 2CODA 3QBVB 2EMSA 2I5FA 5LG4B 2AEHA 3ODOA 2COCA 1K5GB 3PVLA 1WGQA 3OHMB 3DXDA 3ULBA 5EFXA 1EAZA 4CHJA 4DBBA 2DHIA 2D9VA 3FVCA 2DKPA 4IOYX 4K17A 2D10A 1XODA 2CRFA 1U29A 3RCPA 4GOUA 4A6FA 2DHKA 1KZ7A 1XD4A 1MAIA 4TYZA 2ROVA 4HHVA 1FGZA 2PZ1A 5HE1A 4QJ3B 4KAXB 1U5EA 4HB2B 3DXCA 1X1GA 4F7GA 1QC6A 2Z0QA 1BAKA 3IVFA 4HAZB 5LOPB 2H7EA 2D9YA 2FJLA 3AJ4A 1BTNA 1SGHA 4A6FB 1W1DA 3WYFB 2OTXA 3CIKA 4WSFA 5J3QA 4MT7A 1U5FA 3A8PA 4HDOA 2DX5A 1ZC3B 1P5TA 2RUKB 4P7IA 1QQGA 5HE0A 1U2BA 3SNHA 2Q13A 4F7UP 2LYDA 1RJ2A 3MPXA 4Y94A 2DN6A 2GS0A 3GYOA 3U8ZA 1LB1A 2RNRB 2UZSA 5J3TA 1SHCA 4HAUB 1GC6A 1OY2A 4XWXA 1GC7A 2ELBA 5JP4A 1NU2A 3U7DA 1E5WA 1UPRA 3TO1A 4H8SA 2P0FA 2RRFA 5L81A 3ML4A 1MPHA 1PLSA 2XQNM 4EKUA 3HQCA 1WJMA 5GOWB 3T06A 4KHBB 2VKIA 2KIGA 3D8FA 4F7HA 5JHGA 2K00A 2VSZA 3TFMA 3ODWA 3HIEA 3BINA 5CLQB 3PVWA 2CAYA 4EJNA 2MFQA 2VRWB 1FHXA 1W1HA 3NSUA 3TW1A 3KSYA 2ELAA 3WA0A 1X05A 1MIXA 2Y8FA 2UVMA 3UZTA 1TQZA 5JHHA 2KCJA 1DYNA 3KZ1A 3NW8A 4HB3B 2NMBA 1X1FA 1ZSQA 1XCGA 3VIAA 1N3HA 2GCLA 3HK0A 1EF1A 2E2XA 1ISNA 1WJ1A 2K49A 2YVCA 4MY6A 4CYEA 3KY9A 3CXBB 4D0NB 5FI0A 2NBVA 2HTHB 5D3XA 3MDBC 4OT1A 1OQNA 1AQCA 4IFSA 3TCAA 1ZC4B 1T77A 4TKNA 1ZYIA 2EC1A 2K2JA 5DH9B 2EJ8A 3LJUX 3HSAA 1NTYA 2CY5A 4Z2NA 1Q67A 2COFA 2QKLA 2DA0A 2OQBA 2N0YA 2YS3A 3SYXA 3SV1A 4IAPA 4YL8A 2Y8GA 5D3YA 3F0WA 3OANA 2ZPYA 2DYQA 2L2IA 1X86A 5DIFB 3F5RA 2MKRA 1U5DA 1UEFA 2I5CA 2J0JA 2YS1A 1Z87A 4L6EA 2DLWA 1MK9B 3NWFA 2GJYA 1H10A 1XX0A 2Z0OA 1NI2A 3PP2A 2KUPA 4DIXA 3FEHA 1KI1B 2UZRA 2MWNB 1WI1A 2LULA 2MDXA 3PEGA 2Y7BA 2LKOA 1GG3A 5KCVA 2D11A 2R09A 1ZVRA 2DTCA 2K8EA 1UNRA 3P7ZA 1U27A 5HE3A 1I2HA 1V61A 2RVBB 3KRXA 1OMWA 2YT1A 2D9ZA 4HAVB 2J0KA 2RSGA 4HATB 3PZDA 1V88A
chains in the Genus database with same CATH topology
3FM8C 1BTKA 2M14A 3A8QA 2M38A 2I1KA 1WG7A 2QKMA 4HAXB 2Z0PA 4HDQA 1EVHA 2BCJA 2H7DA 4GMXB 3PVUA 1X11A 1W1GA 3X23A 1ZM0A 5J3YA 1DDMA 5D27A 3V5WA 2AL6A 4WVFB 5LONB 2D2QA 3VOQA 3D8EA 1FHWA 5C5BA 1DDWA 2ADZA 2DX1A 1V5PA 5D3WA 2HE7A 2J59M 4K2OA 2DFKA 2L1CA 4ZRKA 3AU5A 1FOEA 1UPQA 2DHJA 2P0DA 1BWNA 1PFJA 4YONA 2P0HA 4HB0B 3ODXA 2ROZB 1MKEA 1P6SA 2DKQA 1WGUA 2KGXB 2V76A 2YS5A 1EGXA 5JLJB 3AU4A 1U5GA 2D4QA 2IFSA 1V5MA 4KHOA 1FHOA 3SO6A 3O96A 1M7EA 2JP2A 4BBKA 1DBHA 2EMTA 2D9XA 1IRSA 4A6KA 2GCJA 4ZRIA 1XR0B 1H4RA 2X18A 4GPTB 3A98B 5FI1A 4KVGB 4K2PA 1FGYA 5DHAB 3N7CA 3HW2B 3ZDTA 4NY0A 2COAA 2YF0A 5C16A 3TVVA 4GN1A 5C79A 1V5UA 4DX8A 4PNKA 1DROA 1PMSA 3QIJA 2J0MA 4B6HA 4KHAA 1I7AA 2R0DA 2W2XC 1P3RA 1K5DB 1KZGA 3SUZA 4HB4B 2YSZA 3DXEA 3M1IB 4GZUA 2YRYA 1LW3A 1MIZB 1MK7B 2IYBA 4PQ0A 2W2WA 1FB8A 4ZRJA 2I1JA 2LOZA 4A6HA 3ZVRA 4K81A 2CY4A 1UNPA 1J19A 4EMOA 4MK0A 1XKEA 1B55A 2P8VA 1V89A 2D9WA 5HE2A 2LOXA 3G9WA 1NTVA 3FSSA 3P6AA 3PSCA 1TXDA 1WVHA 3D8DA 1Y19B 3PG7A 2N23A 4HAYB 4Z2MB 2W2XD 1TJ6A 1Y5OA 1AWEA 3GYPA 4HAWB 1J0WA 5D3VA 4CHMA 4A5KA 2DYNA 5DI9B 2RLOA 3KRWA 3BJIA 4DXAB 5C6RA 2YT0A 4WJ7A 5KQ4A 2NZ8B 4GMVA 1UNQA 2LG1A 5C5BB 1RRPB 1DDVA 2G35A 5CLLB 4NSWA 2RGNB 1FAOA 5KQ1A 3QWMA 1M7RA 3ULCA 4C0AA 2K2UA 4DX90 5DHFB 4GXBA 2CODA 3QBVB 2EMSA 2I5FA 2AEHA 3ODOA 2COCA 1K5GB 3PVLA 1WGQA 3DXDA 3ULBA 5EFXA 1EAZA 4CHJA 4DBBA 2DHIA 2D9VA 2DKPA 4IOYX 4K17A 2D10A 1XODA 2CRFA 1U29A 3RCPA 4A6FA 2DHKA 1KZ7A 1XD4A 1MAIA 4TYZA 2ROVA 4HHVA 1FGZA 2PZ1A 5HE1A 4KAXB 1U5EA 4HB2B 3DXCA 1X1GA 4F7GA 1QC6A 2Z0QA 1BAKA 3IVFA 4HAZB 5LOPB 2H7EA 2D9YA 2FJLA 3AJ4A 1BTNA 1SGHA 4A6FB 1W1DA 3WYFB 2OTXA 3CIKA 4WSFA 5J3QA 4MT7A 1U5FA 3A8PA 4HDOA 2DX5A 1ZC3B 1P5TA 2RUKB 4P7IA 1QQGA 5HE0A 1U2BA 3SNHA 2Q13A 4F7UP 2LYDA 1RJ2A 3MPXA 4Y94A 2DN6A 2GS0A 3GYOA 3U8ZA 1LB1A 2RNRB 2UZSA 5J3TA 1SHCA 4HAUB 1GC6A 1OY2A 4XWXA 1GC7A 2ELBA 5JP4A 1NU2A 3U7DA 1E5WA 1UPRA 3TO1A 4H8SA 2P0FA 5L81A 3ML4A 1MPHA 1PLSA 2XQNM 4EKUA 3HQCA 1WJMA 5GOWB 3T06A 4KHBB 2VKIA 3D8FA 4F7HA 5JHGA 2K00A 2VSZA 3TFMA 3ODWA 3BINA 5CLQB 3PVWA 2CAYA 4EJNA 2MFQA 2VRWB 1FHXA 1W1HA 3NSUA 3TW1A 3KSYA 2ELAA 3WA0A 1X05A 1MIXA 2Y8FA 2UVMA 3UZTA 1TQZA 5JHHA 2KCJA 1DYNA 3KZ1A 4HB3B 2NMBA 1X1FA 1ZSQA 1XCGA 3VIAA 1N3HA 2GCLA 3HK0A 1EF1A 2E2XA 1ISNA 1WJ1A 4MY6A 2YVCA 4CYEA 3KY9A 3CXBB 4D0NB 5FI0A 2HTHB 5D3XA 3MDBC 1OQNA 1AQCA 4IFSA 3TCAA 1ZC4B 4TKNA 2EC1A 2K2JA 5DH9B 2EJ8A 3LJUX 1NTYA 2CY5A 4Z2NA 1Q67A 2COFA 2QKLA 2DA0A 2OQBA 2N0YA 2YS3A 3SYXA 3SV1A 4IAPA 4YL8A 2Y8GA 5D3YA 3F0WA 3OANA 2ZPYA 2DYQA 2L2IA 1X86A 5DIFB 3F5RA 2MKRA 1U5DA 1UEFA 2I5CA 2J0JA 2YS1A 1Z87A 4L6EA 2DLWA 1MK9B 2GJYA 1H10A 1XX0A 2Z0OA 1NI2A 3PP2A 2KUPA 3FEHA 1KI1B 2UZRA 2MWNB 1WI1A 2LULA 2MDXA 3PEGA 2Y7BA 2LKOA 1GG3A 5KCVA 2D11A 2R09A 1ZVRA 2DTCA 1UNRA 3P7ZA 1U27A 5HE3A 1I2HA 1V61A 2RVBB 3KRXA 1OMWA 2YT1A 2D9ZA 4HAVB 2J0KA 2RSGA 4HATB 3PZDA 1V88A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FM8 C;  1BTK A;  2M14 A;  3A8Q A;  2M38 A;  2I1K A;  1WG7 A;  2QKM A;  4HAX B;  2Z0P A;  4HDQ A;  1EVH A;  2BCJ A;  2H7D A;  4GMX B;  3PVU A;  1X11 A;  1W1G A;  3X23 A;  1ZM0 A;  5J3Y A;  1DDM A;  5D27 A;  3V5W A;  2AL6 A;  4WVF B;  5LON B;  2D2Q A;  3VOQ A;  3D8E A;  1FHW A;  5C5B A;  1DDW A;  2ADZ A;  2DX1 A;  1V5P A;  5D3W A;  2HE7 A;  2J59 M;  4K2O A;  2DFK A;  2L1C A;  4ZRK A;  3AU5 A;  1FOE A;  1UPQ A;  2DHJ A;  2P0D A;  1BWN A;  1PFJ A;  4YON A;  2P0H A;  4HB0 B;  3ODX A;  2ROZ B;  1MKE A;  1P6S A;  2DKQ A;  1WGU A;  2KGX B;  2V76 A;  2YS5 A;  1EGX A;  5JLJ B;  3AU4 A;  1U5G A;  2D4Q A;  2IFS A;  1V5M A;  4KHO A;  1FHO A;  3SO6 A;  3O96 A;  1M7E A;  2JP2 A;  4BBK A;  1DBH A;  2EMT A;  2D9X A;  1IRS A;  4A6K A;  2GCJ A;  4ZRI A;  1XR0 B;  1H4R A;  2X18 A;  4GPT B;  3A98 B;  5FI1 A;  4KVG B;  4K2P A;  1FGY A;  5DHA B;  3N7C A;  3HW2 B;  3ZDT A;  4NY0 A;  2COA A;  2YF0 A;  5C16 A;  3TVV A;  4GN1 A;  5C79 A;  1V5U A;  4DX8 A;  4PNK A;  1DRO A;  1PMS A;  3QIJ A;  2J0M A;  4B6H A;  4KHA A;  1I7A A;  2R0D A;  2W2X C;  1P3R A;  1K5D B;  1KZG A;  3SUZ A;  4HB4 B;  2YSZ A;  3DXE A;  3M1I B;  4GZU A;  2YRY A;  1LW3 A;  1MIZ B;  1MK7 B;  2IYB A;  4PQ0 A;  2W2W A;  1FB8 A;  4ZRJ A;  2I1J A;  2LOZ A;  4A6H A;  3ZVR A;  4K81 A;  2CY4 A;  1UNP A;  1J19 A;  4EMO A;  4MK0 A;  1XKE A;  1B55 A;  2P8V A;  1V89 A;  2D9W A;  5HE2 A;  2LOX A;  3G9W A;  1NTV A;  3FSS A;  3P6A A;  3PSC A;  1TXD A;  1WVH A;  3D8D A;  1Y19 B;  3PG7 A;  2N23 A;  4HAY B;  4Z2M B;  2W2X D;  1TJ6 A;  1Y5O A;  1AWE A;  3GYP A;  4HAW B;  1J0W A;  5D3V A;  4CHM A;  4A5K A;  2DYN A;  5DI9 B;  2RLO A;  3KRW A;  3BJI A;  4DXA B;  5C6R A;  2YT0 A;  4WJ7 A;  5KQ4 A;  2NZ8 B;  4GMV A;  1UNQ A;  2LG1 A;  5C5B B;  1RRP B;  1DDV A;  2G35 A;  5CLL B;  4NSW A;  2RGN B;  1FAO A;  5KQ1 A;  3QWM A;  1M7R A;  3ULC A;  4C0A A;  2K2U A;  4DX9 0;  5DHF B;  4GXB A;  2COD A;  3QBV B;  2EMS A;  2I5F A;  2AEH A;  3ODO A;  2COC A;  1K5G B;  3PVL A;  1WGQ A;  3DXD A;  3ULB A;  5EFX A;  1EAZ A;  4CHJ A;  4DBB A;  2DHI A;  2D9V A;  2DKP A;  4IOY X;  4K17 A;  2D10 A;  1XOD A;  2CRF A;  1U29 A;  3RCP A;  4A6F A;  2DHK A;  1KZ7 A;  1XD4 A;  1MAI A;  4TYZ A;  2ROV A;  4HHV A;  1FGZ A;  2PZ1 A;  5HE1 A;  4KAX B;  1U5E A;  4HB2 B;  3DXC A;  1X1G A;  4F7G A;  1QC6 A;  2Z0Q A;  1BAK A;  3IVF A;  4HAZ B;  5LOP B;  2H7E A;  2D9Y A;  2FJL A;  3AJ4 A;  1BTN A;  1SGH A;  4A6F B;  1W1D A;  3WYF B;  2OTX A;  3CIK A;  4WSF A;  5J3Q A;  4MT7 A;  1U5F A;  3A8P A;  4HDO A;  2DX5 A;  1ZC3 B;  1P5T A;  2RUK B;  4P7I A;  1QQG A;  5HE0 A;  1U2B A;  3SNH A;  2Q13 A;  4F7U P;  2LYD A;  1RJ2 A;  3MPX A;  4Y94 A;  2DN6 A;  2GS0 A;  3GYO A;  3U8Z A;  1LB1 A;  2RNR B;  2UZS A;  5J3T A;  1SHC A;  4HAU B;  1GC6 A;  1OY2 A;  4XWX A;  1GC7 A;  2ELB A;  5JP4 A;  1NU2 A;  3U7D A;  1E5W A;  1UPR A;  3TO1 A;  4H8S A;  2P0F A;  5L81 A;  3ML4 A;  1MPH A;  1PLS A;  2XQN M;  4EKU A;  3HQC A;  1WJM A;  5GOW B;  3T06 A;  4KHB B;  2VKI A;  3D8F A;  4F7H A;  5JHG A;  2K00 A;  2VSZ A;  3TFM A;  3ODW A;  3BIN A;  5CLQ B;  3PVW A;  2CAY A;  4EJN A;  2MFQ A;  2VRW B;  1FHX A;  1W1H A;  3NSU A;  3TW1 A;  3KSY A;  2ELA A;  3WA0 A;  1X05 A;  1MIX A;  2Y8F A;  2UVM A;  3UZT A;  1TQZ A;  5JHH A;  2KCJ A;  1DYN A;  3KZ1 A;  4HB3 B;  2NMB A;  1X1F A;  1ZSQ A;  1XCG A;  3VIA A;  1N3H A;  2GCL A;  3HK0 A;  1EF1 A;  2E2X A;  1ISN A;  1WJ1 A;  4MY6 A;  2YVC A;  4CYE A;  3KY9 A;  3CXB B;  4D0N B;  5FI0 A;  2HTH B;  5D3X A;  3MDB C;  1OQN A;  1AQC A;  4IFS A;  3TCA A;  1ZC4 B;  4TKN A;  2EC1 A;  2K2J A;  5DH9 B;  2EJ8 A;  3LJU X;  1NTY A;  2CY5 A;  4Z2N A;  1Q67 A;  2COF A;  2QKL A;  2DA0 A;  2OQB A;  2N0Y A;  2YS3 A;  3SYX A;  3SV1 A;  4IAP A;  4YL8 A;  2Y8G A;  5D3Y A;  3F0W A;  3OAN A;  2ZPY A;  2DYQ A;  2L2I A;  1X86 A;  5DIF B;  3F5R A;  2MKR A;  1U5D A;  1UEF A;  2I5C A;  2J0J A;  2YS1 A;  1Z87 A;  4L6E A;  2DLW A;  1MK9 B;  2GJY A;  1H10 A;  1XX0 A;  2Z0O A;  1NI2 A;  3PP2 A;  2KUP A;  3FEH A;  1KI1 B;  2UZR A;  2MWN B;  1WI1 A;  2LUL A;  2MDX A;  3PEG A;  2Y7B A;  2LKO A;  1GG3 A;  5KCV A;  2D11 A;  2R09 A;  1ZVR A;  2DTC A;  1UNR A;  3P7Z A;  1U27 A;  5HE3 A;  1I2H A;  1V61 A;  2RVB B;  3KRX A;  1OMW A;  2YT1 A;  2D9Z A;  4HAV B;  2J0K A;  2RSG A;  4HAT B;  3PZD A;  1V88 A; 
#chains in the Genus database with same CATH topology
 3FM8 C;  2KUQ A;  1BTK A;  2M14 A;  3A8Q A;  2M38 A;  2I1K A;  1WG7 A;  2QKM A;  4HAX B;  2Z0P A;  4HDQ A;  1EVH A;  2BCJ A;  2H7D A;  4GMX B;  3DCX A;  3PVU A;  1X11 A;  1W1G A;  3X23 A;  1ZM0 A;  5J3Y A;  1DDM A;  5D27 A;  3V5W A;  2AL6 A;  4WVF B;  5LON B;  2D2Q A;  3VOQ A;  3D8E A;  1FHW A;  2KR0 A;  5C5B A;  1DDW A;  2ADZ A;  2DX1 A;  1V5P A;  5D3W A;  2HE7 A;  3NWD A;  2J59 M;  4K2O A;  2DFK A;  2L1C A;  4ZRK A;  3AU5 A;  1FOE A;  1UPQ A;  2DHJ A;  2R2Y A;  2P0D A;  1BWN A;  2Z14 A;  1PFJ A;  4YON A;  2P0H A;  4HB0 B;  2ZKM X;  3ODX A;  2ROZ B;  1MKE A;  1P6S A;  2DKQ A;  1WGU A;  2KGX B;  2V76 A;  2YS5 A;  1EGX A;  5JLJ B;  3AU4 A;  1U5G A;  2FJU B;  1MI1 A;  2D4Q A;  2IFS A;  1V5M A;  4KHO A;  1FHO A;  3SO6 A;  3O96 A;  1M7E A;  2JP2 A;  2Z13 A;  4BBK A;  1DBH A;  2EMT A;  2D9X A;  3A58 A;  1IRS A;  4A6K A;  2GCJ A;  4ZRI A;  1XR0 B;  2KIE A;  1H4R A;  2Z4D A;  4QJ4 B;  4L1R A;  2X18 A;  4GPT B;  3A98 B;  5FI1 A;  4KVG B;  4K2P A;  1FGY A;  5DHA B;  3N7C A;  3HW2 B;  3ZDT A;  4NY0 A;  2COA A;  2YF0 A;  5C16 A;  4QXA B;  3TVV A;  4GN1 A;  4D6W A;  5C79 A;  1V5U A;  4DX8 A;  4PNK A;  1DRO A;  1PMS A;  3QIJ A;  2J0M A;  4B6H A;  4KHA A;  1I7A A;  2R0D A;  2W2X C;  1P3R A;  1K5D B;  1KZG A;  3SUZ A;  4HB4 B;  2YSZ A;  3DXE A;  3M1I B;  4GZU A;  2YRY A;  1LW3 A;  1MIZ B;  4KHB A;  1MK7 B;  4OSN A;  2IYB A;  4PQ0 A;  2W2W A;  1FB8 A;  4ZRJ A;  2I1J A;  2LOZ A;  4A6H A;  5I2S A;  5I2M A;  3ZVR A;  4K81 A;  2CY4 A;  1UNP A;  4HSI A;  1J19 A;  4EMO A;  4MK0 A;  5M4Y B;  1XKE A;  1B55 A;  2P8V A;  1V89 A;  2D9W A;  5HE2 A;  2LOX A;  3G9W A;  1NTV A;  3FSS A;  3P6A A;  3PSC A;  1TXD A;  1WVH A;  3D8D A;  1Y19 B;  3PG7 A;  2N23 A;  4HAY B;  4Z2M B;  2W2X D;  1TJ6 A;  1Y5O A;  2YT2 A;  3NWA A;  1AWE A;  3GYP A;  4HAW B;  1J0W A;  5D3V A;  4GNK B;  4CHM A;  4CSQ A;  4A5K A;  4QJ5 B;  2DYN A;  5DI9 B;  2RLO A;  5IRS A;  2Z59 A;  3KRW A;  3BJI A;  4DXA B;  5C6R A;  2YT0 A;  4WJ7 A;  5KQ4 A;  2NZ8 B;  4GMV A;  3B77 A;  1UNQ A;  2GUM A;  2LG1 A;  3U12 A;  5C5B B;  1RRP B;  1DDV A;  2G35 A;  5CLL B;  4NSW A;  2RGN B;  1FAO A;  5KQ1 A;  3QWM A;  1M7R A;  3ULC A;  4C0A A;  2K2U A;  4DX9 0;  5DHF B;  4GXB A;  2COD A;  3QBV B;  2EMS A;  2I5F A;  5LG4 B;  2AEH A;  3ODO A;  2COC A;  1K5G B;  3PVL A;  1WGQ A;  3OHM B;  3DXD A;  3ULB A;  5EFX A;  1EAZ A;  4CHJ A;  4DBB A;  2DHI A;  2D9V A;  3FVC A;  2DKP A;  4IOY X;  4K17 A;  2D10 A;  1XOD A;  2CRF A;  1U29 A;  3RCP A;  4GOU A;  4A6F A;  2DHK A;  1KZ7 A;  1XD4 A;  1MAI A;  4TYZ A;  2ROV A;  4HHV A;  1FGZ A;  2PZ1 A;  5HE1 A;  4QJ3 B;  4KAX B;  1U5E A;  4HB2 B;  3DXC A;  1X1G A;  4F7G A;  1QC6 A;  2Z0Q A;  1BAK A;  3IVF A;  4HAZ B;  5LOP B;  2H7E A;  2D9Y A;  2FJL A;  3AJ4 A;  1BTN A;  1SGH A;  4A6F B;  1W1D A;  3WYF B;  2OTX A;  3CIK A;  4WSF A;  5J3Q A;  4MT7 A;  1U5F A;  3A8P A;  4HDO A;  2DX5 A;  1ZC3 B;  1P5T A;  2RUK B;  4P7I A;  1QQG A;  5HE0 A;  1U2B A;  3SNH A;  2Q13 A;  4F7U P;  2LYD A;  1RJ2 A;  3MPX A;  4Y94 A;  2DN6 A;  2GS0 A;  3GYO A;  3U8Z A;  1LB1 A;  2RNR B;  2UZS A;  5J3T A;  1SHC A;  4HAU B;  1GC6 A;  1OY2 A;  4XWX A;  1GC7 A;  2ELB A;  5JP4 A;  1NU2 A;  3U7D A;  1E5W A;  1UPR A;  3TO1 A;  4H8S A;  2P0F A;  2RRF A;  5L81 A;  3ML4 A;  1MPH A;  1PLS A;  2XQN M;  4EKU A;  3HQC A;  1WJM A;  5GOW B;  3T06 A;  4KHB B;  2VKI A;  2KIG A;  3D8F A;  4F7H A;  5JHG A;  2K00 A;  2VSZ A;  3TFM A;  3ODW A;  3HIE A;  3BIN A;  5CLQ B;  3PVW A;  2CAY A;  4EJN A;  2MFQ A;  2VRW B;  1FHX A;  1W1H A;  3NSU A;  3TW1 A;  3KSY A;  2ELA A;  3WA0 A;  1X05 A;  1MIX A;  2Y8F A;  2UVM A;  3UZT A;  1TQZ A;  5JHH A;  2KCJ A;  1DYN A;  3KZ1 A;  3NW8 A;  4HB3 B;  2NMB A;  1X1F A;  1ZSQ A;  1XCG A;  3VIA A;  1N3H A;  2GCL A;  3HK0 A;  1EF1 A;  2E2X A;  1ISN A;  1WJ1 A;  2K49 A;  2YVC A;  4MY6 A;  4CYE A;  3KY9 A;  3CXB B;  4D0N B;  5FI0 A;  2NBV A;  2HTH B;  5D3X A;  3MDB C;  4OT1 A;  1OQN A;  1AQC A;  4IFS A;  3TCA A;  1ZC4 B;  1T77 A;  4TKN A;  1ZYI A;  2EC1 A;  2K2J A;  5DH9 B;  2EJ8 A;  3LJU X;  3HSA A;  1NTY A;  2CY5 A;  4Z2N A;  1Q67 A;  2COF A;  2QKL A;  2DA0 A;  2OQB A;  2N0Y A;  2YS3 A;  3SYX A;  3SV1 A;  4IAP A;  4YL8 A;  2Y8G A;  5D3Y A;  3F0W A;  3OAN A;  2ZPY A;  2DYQ A;  2L2I A;  1X86 A;  5DIF B;  3F5R A;  2MKR A;  1U5D A;  1UEF A;  2I5C A;  2J0J A;  2YS1 A;  1Z87 A;  4L6E A;  2DLW A;  1MK9 B;  3NWF A;  2GJY A;  1H10 A;  1XX0 A;  2Z0O A;  1NI2 A;  3PP2 A;  2KUP A;  4DIX A;  3FEH A;  1KI1 B;  2UZR A;  2MWN B;  1WI1 A;  2LUL A;  2MDX A;  3PEG A;  2Y7B A;  2LKO A;  1GG3 A;  5KCV A;  2D11 A;  2R09 A;  1ZVR A;  2DTC A;  2K8E A;  1UNR A;  3P7Z A;  1U27 A;  5HE3 A;  1I2H A;  1V61 A;  2RVB B;  3KRX A;  1OMW A;  2YT1 A;  2D9Z A;  4HAV B;  2J0K A;  2RSG A;  4HAT B;  3PZD A;  1V88 A; 
#chains in the Genus database with same CATH homology
 3FM8 C;  1BTK A;  2M14 A;  3A8Q A;  2M38 A;  2I1K A;  1WG7 A;  2QKM A;  4HAX B;  2Z0P A;  4HDQ A;  1EVH A;  2BCJ A;  2H7D A;  4GMX B;  3PVU A;  1X11 A;  1W1G A;  3X23 A;  1ZM0 A;  5J3Y A;  1DDM A;  5D27 A;  3V5W A;  2AL6 A;  4WVF B;  5LON B;  2D2Q A;  3VOQ A;  3D8E A;  1FHW A;  5C5B A;  1DDW A;  2ADZ A;  2DX1 A;  1V5P A;  5D3W A;  2HE7 A;  2J59 M;  4K2O A;  2DFK A;  2L1C A;  4ZRK A;  3AU5 A;  1FOE A;  1UPQ A;  2DHJ A;  2P0D A;  1BWN A;  1PFJ A;  4YON A;  2P0H A;  4HB0 B;  3ODX A;  2ROZ B;  1MKE A;  1P6S A;  2DKQ A;  1WGU A;  2KGX B;  2V76 A;  2YS5 A;  1EGX A;  5JLJ B;  3AU4 A;  1U5G A;  2D4Q A;  2IFS A;  1V5M A;  4KHO A;  1FHO A;  3SO6 A;  3O96 A;  1M7E A;  2JP2 A;  4BBK A;  1DBH A;  2EMT A;  2D9X A;  1IRS A;  4A6K A;  2GCJ A;  4ZRI A;  1XR0 B;  1H4R A;  2X18 A;  4GPT B;  3A98 B;  5FI1 A;  4KVG B;  4K2P A;  1FGY A;  5DHA B;  3N7C A;  3HW2 B;  3ZDT A;  4NY0 A;  2COA A;  2YF0 A;  5C16 A;  3TVV A;  4GN1 A;  5C79 A;  1V5U A;  4DX8 A;  4PNK A;  1DRO A;  1PMS A;  3QIJ A;  2J0M A;  4B6H A;  4KHA A;  1I7A A;  2R0D A;  2W2X C;  1P3R A;  1K5D B;  1KZG A;  3SUZ A;  4HB4 B;  2YSZ A;  3DXE A;  3M1I B;  4GZU A;  2YRY A;  1LW3 A;  1MIZ B;  1MK7 B;  2IYB A;  4PQ0 A;  2W2W A;  1FB8 A;  4ZRJ A;  2I1J A;  2LOZ A;  4A6H A;  3ZVR A;  4K81 A;  2CY4 A;  1UNP A;  1J19 A;  4EMO A;  4MK0 A;  1XKE A;  1B55 A;  2P8V A;  1V89 A;  2D9W A;  5HE2 A;  2LOX A;  3G9W A;  1NTV A;  3FSS A;  3P6A A;  3PSC A;  1TXD A;  1WVH A;  3D8D A;  1Y19 B;  3PG7 A;  2N23 A;  4HAY B;  4Z2M B;  2W2X D;  1TJ6 A;  1Y5O A;  1AWE A;  3GYP A;  4HAW B;  1J0W A;  5D3V A;  4CHM A;  4A5K A;  2DYN A;  5DI9 B;  2RLO A;  3KRW A;  3BJI A;  4DXA B;  5C6R A;  2YT0 A;  4WJ7 A;  5KQ4 A;  2NZ8 B;  4GMV A;  1UNQ A;  2LG1 A;  5C5B B;  1RRP B;  1DDV A;  2G35 A;  5CLL B;  4NSW A;  2RGN B;  1FAO A;  5KQ1 A;  3QWM A;  1M7R A;  3ULC A;  4C0A A;  2K2U A;  4DX9 0;  5DHF B;  4GXB A;  2COD A;  3QBV B;  2EMS A;  2I5F A;  2AEH A;  3ODO A;  2COC A;  1K5G B;  3PVL A;  1WGQ A;  3DXD A;  3ULB A;  5EFX A;  1EAZ A;  4CHJ A;  4DBB A;  2DHI A;  2D9V A;  2DKP A;  4IOY X;  4K17 A;  2D10 A;  1XOD A;  2CRF A;  1U29 A;  3RCP A;  4A6F A;  2DHK A;  1KZ7 A;  1XD4 A;  1MAI A;  4TYZ A;  2ROV A;  4HHV A;  1FGZ A;  2PZ1 A;  5HE1 A;  4KAX B;  1U5E A;  4HB2 B;  3DXC A;  1X1G A;  4F7G A;  1QC6 A;  2Z0Q A;  1BAK A;  3IVF A;  4HAZ B;  5LOP B;  2H7E A;  2D9Y A;  2FJL A;  3AJ4 A;  1BTN A;  1SGH A;  4A6F B;  1W1D A;  3WYF B;  2OTX A;  3CIK A;  4WSF A;  5J3Q A;  4MT7 A;  1U5F A;  3A8P A;  4HDO A;  2DX5 A;  1ZC3 B;  1P5T A;  2RUK B;  4P7I A;  1QQG A;  5HE0 A;  1U2B A;  3SNH A;  2Q13 A;  4F7U P;  2LYD A;  1RJ2 A;  3MPX A;  4Y94 A;  2DN6 A;  2GS0 A;  3GYO A;  3U8Z A;  1LB1 A;  2RNR B;  2UZS A;  5J3T A;  1SHC A;  4HAU B;  1GC6 A;  1OY2 A;  4XWX A;  1GC7 A;  2ELB A;  5JP4 A;  1NU2 A;  3U7D A;  1E5W A;  1UPR A;  3TO1 A;  4H8S A;  2P0F A;  5L81 A;  3ML4 A;  1MPH A;  1PLS A;  2XQN M;  4EKU A;  3HQC A;  1WJM A;  5GOW B;  3T06 A;  4KHB B;  2VKI A;  3D8F A;  4F7H A;  5JHG A;  2K00 A;  2VSZ A;  3TFM A;  3ODW A;  3BIN A;  5CLQ B;  3PVW A;  2CAY A;  4EJN A;  2MFQ A;  2VRW B;  1FHX A;  1W1H A;  3NSU A;  3TW1 A;  3KSY A;  2ELA A;  3WA0 A;  1X05 A;  1MIX A;  2Y8F A;  2UVM A;  3UZT A;  1TQZ A;  5JHH A;  2KCJ A;  1DYN A;  3KZ1 A;  4HB3 B;  2NMB A;  1X1F A;  1ZSQ A;  1XCG A;  3VIA A;  1N3H A;  2GCL A;  3HK0 A;  1EF1 A;  2E2X A;  1ISN A;  1WJ1 A;  4MY6 A;  2YVC A;  4CYE A;  3KY9 A;  3CXB B;  4D0N B;  5FI0 A;  2HTH B;  5D3X A;  3MDB C;  1OQN A;  1AQC A;  4IFS A;  3TCA A;  1ZC4 B;  4TKN A;  2EC1 A;  2K2J A;  5DH9 B;  2EJ8 A;  3LJU X;  1NTY A;  2CY5 A;  4Z2N A;  1Q67 A;  2COF A;  2QKL A;  2DA0 A;  2OQB A;  2N0Y A;  2YS3 A;  3SYX A;  3SV1 A;  4IAP A;  4YL8 A;  2Y8G A;  5D3Y A;  3F0W A;  3OAN A;  2ZPY A;  2DYQ A;  2L2I A;  1X86 A;  5DIF B;  3F5R A;  2MKR A;  1U5D A;  1UEF A;  2I5C A;  2J0J A;  2YS1 A;  1Z87 A;  4L6E A;  2DLW A;  1MK9 B;  2GJY A;  1H10 A;  1XX0 A;  2Z0O A;  1NI2 A;  3PP2 A;  2KUP A;  3FEH A;  1KI1 B;  2UZR A;  2MWN B;  1WI1 A;  2LUL A;  2MDX A;  3PEG A;  2Y7B A;  2LKO A;  1GG3 A;  5KCV A;  2D11 A;  2R09 A;  1ZVR A;  2DTC A;  1UNR A;  3P7Z A;  1U27 A;  5HE3 A;  1I2H A;  1V61 A;  2RVB B;  3KRX A;  1OMW A;  2YT1 A;  2D9Z A;  4HAV B;  2J0K A;  2RSG A;  4HAT B;  3PZD A;  1V88 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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