1H10A

High resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to ins(1,3,4,5)-tetrakisphophate
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
117
structure length
117
Chain Sequence
SMSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords RAC-ALPHA SERINE/THREONINE KINASE
publication title High Resolution Structure of the Pleckstrin Homology Domain of Protein Kinase B/Akt Bound to Phosphatidylinositol (3,4,5)-Trisphosphate
pubmed doi rcsb
source organism Homo sapiens
total genus 29
structure length 117
sequence length 117
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2002-07-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1h10A00
1IRSA 3DXEA 3VIAA 5D3YA 2RVBB 4K2OA 2CRFA 3HK0A 5DHFB 3ODXA 2KUPA 1ZM0A 1V61A 4DX90 2DN6A 1DDVA 1MPHA 5D27A 2D9WA 4A6HA 1M7RA 1DDMA 1BWNA 5HE0A 1K5DB 3IVFA 4IFSA 2DX1A 1B55A 2YT0A 1X05A 3CXBB 1TXDA 1Y5OA 3PSCA 5C5BA 4DX8A 5CLQB 5KQ4A 5LOPB 2MDXA 1WGUA 2R0DA 1W1GA 4GMXB 1AQCA 4A5KA 3F0WA 2YT1A 5JHGA 1BTKA 1NU2A 3OANA 1WJ1A 2GS0A 4B6HA 3PVUA 2W2WA 1QC6A 1V5PA 4HAXB 1GC6A 1GG3A 2Y7BA 5EFXA 3ZVRA 1FAOA 1UPQA 4HAZB 4ZRJA 2ELAA 3SV1A 5LONB 3X23A 3FM8C 4TKNA 5DHAB 4MY6A 2RSGA 1BTNA 2HTHB 1WJMA 5D3VA 1KZGA 2RUKB 3HW2B 2M38A 1DYNA 3F5RA 2J0JA 1X11A 4EJNA 4HAVB 4A6FA 5CLLB 1ISNA 2ROZB 2DHKA 2N0YA 1WG7A 1X1FA 1J0WA 3P6AA 2DHJA 2KGXB 5DI9B 2GJYA 3ML4A 4YL8A 1KZ7A 1W1DA 2GCLA 3A8PA 2D9YA 3PEGA 2ELBA 3PG7A 1Z87A 1MK9B 1MIXA 2Q13A 2UVMA 1U27A 1FB8A 1P6SA 3A8QA 2W2XD 1UNPA 2ROVA 1U2BA 3TCAA 3TW1A 2YRYA 1OY2A 4YONA 1J19A 1U5FA 3PZDA 2D11A 1SHCA 3PVWA 4GN1A 3PVLA 4CHJA 2LYDA 2COAA 3AJ4A 2L2IA 1V89A 1AWEA 4GXBA 2DKPA 3GYOA 4H8SA 4KHBB 2PZ1A 1I7AA 1ZC4B 1XR0B 4K2PA 4KAXB 3BINA 1H4RA 5GOWB 4NSWA 3KRXA 3PP2A 4EKUA 1Q67A 1DROA 4TYZA 3CIKA 3D8EA 4WVFB 2YF0A 4HHVA 1EVHA 2UZRA 1KI1B 4Z2MB 2RNRB 2V76A 5KQ1A 2K2JA 1UPRA 1NTVA 2N23A 2AL6A 2EC1A 5C79A 4HAYB 4HAWB 3MDBC 1Y19B 3V5WA 1FHXA 1OQNA 2YS5A 1XODA 1SGHA 4MK0A 5C6RA 2M14A 2OTXA 2VSZA 4KVGB 2D4QA 2MWNB 1ZC3B 3VOQA 3D8DA 3G9WA 4DXAB 5JHHA 5J3TA 5FI0A 2YVCA 2D2QA 1U5DA 1K5GB 5J3QA 2ZPYA 2LKOA 4K81A 5DIFB 1P5TA 1DDWA 1FHWA 4Y94A 2J0KA 2L1CA 4DBBA 3AU4A 2QKLA 2I5FA 4HB2B 1M7EA 3O96A 4KHAA 2BCJA 2MKRA 3QBVB 3NSUA 5HE3A 1X1GA 1BAKA 4MT7A 3SNHA 2IFSA 2H7EA 2RGNB 5C5BB 1XKEA 4HDQA 1FGYA 2LG1A 1TJ6A 1U5GA 3KSYA 1MK7B 1PFJA 2K00A 4HB0B 1FGZA 3WA0A 2LOXA 4CYEA 4WSFA 4GZUA 3FSSA 2VKIA 1QQGA 3QIJA 2I1KA 1FOEA 1TQZA 3ODWA 1ZSQA 4P7IA 2JP2A 2Y8FA 5D3WA 4PNKA 3ODOA 1MKEA 1XX0A 1EAZA 2NZ8B 1V88A 3AU5A 3HQCA 3KY9A 5J3YA 2AEHA 2VRWB 1MAIA 2DTCA 2YS3A 4BBKA 5D3XA 4A6FB 2P0DA 1LW3A 1NI2A 3M1IB 3DXCA 1GC7A 5HE1A 3U8ZA 2DX5A 3WYFB 2CY5A 3TO1A 4Z2NA 2J0MA 2HE7A 4F7GA 1MIZB 1UNRA 1N3HA 2DYQA 4IOYX 4A6KA 2NMBA 2K2UA 3ULCA 2UZSA 4HATB 2D9VA 1U29A 2KCJA 3SYXA 1P3RA 4GPTB 3U7DA 2I5CA 5DH9B 2OQBA 1EGXA 4F7HA 4HDOA 2DLWA 2CY4A 2CAYA 2RLOA 3DXDA 5JP4A 2H7DA 2P0HA 1EF1A 1DBHA 3FEHA 3MPXA 2QKMA 1V5UA 1W1HA 1XCGA 4XWXA 5L81A 2LOZA 2XQNM 2DA0A 2IYBA 3UZTA 1H10A 2Z0PA 2MFQA 4ZRKA 3P7ZA 4HB3B 4PQ0A 2COCA 2EJ8A 3SUZA 2G35A 2J59M 2X18A 1WVHA 1RJ2A 4D0NB 1WI1A 2I1JA 1UNQA 2R09A 4CHMA 1U5EA 2Z0QA 2Z0OA 1FHOA 2DYNA 3KRWA 3BJIA 4K17A 1PLSA 5JLJB 5HE2A 2ADZA 2LULA 2DHIA 3ZDTA 2DFKA 5KCVA 3QWMA 2EMSA 3T06A 1OMWA 2FJLA 1NTYA 2EMTA 3TVVA 2D9XA 1WGQA 1V5MA 2E2XA 2CODA 4WJ7A 2YS1A 2W2XC 3A98B 3LJUX 5FI1A 2D10A 1PMSA 4ZRIA 1I2HA 2P0FA 4NY0A 4F7UP 1X86A 1LB1A 2D9ZA 2GCJA 2COFA 5C16A 1XD4A 4EMOA 4L6EA 2Y8GA 3ULBA 4HB4B 2P8VA 4C0AA 3GYPA 4IAPA 3SO6A 2YSZA 3D8FA 2DKQA 4HAUB 1E5WA 3TFMA 1ZVRA 3KZ1A 3N7CA 1RRPB 1UEFA 4GMVA 4KHOA 3RCPA
chains in the Genus database with same CATH superfamily
1IRSA 3DXEA 3VIAA 5D3YA 2RVBB 4K2OA 2CRFA 3HK0A 5DHFB 3ODXA 2KUPA 1ZM0A 1V61A 4DX90 2DN6A 1DDVA 1MPHA 2GUMA 5D27A 2D9WA 4A6HA 1M7RA 1DDMA 1BWNA 5HE0A 1K5DB 3IVFA 4IFSA 2DX1A 1B55A 2YT0A 1X05A 2Z13A 3CXBB 1TXDA 1Y5OA 3PSCA 5C5BA 4DX8A 2FJUB 5CLQB 5KQ4A 5LOPB 2Z14A 2MDXA 1WGUA 2R0DA 1W1GA 4GMXB 1AQCA 4A5KA 3F0WA 2YT1A 5JHGA 1BTKA 1NU2A 3OANA 1WJ1A 2GS0A 4B6HA 4L1RA 3PVUA 2W2WA 1QC6A 1V5PA 4HAXB 1GC6A 1GG3A 2Y7BA 5EFXA 3ZVRA 1FAOA 1UPQA 4HAZB 4ZRJA 2ELAA 3SV1A 5LONB 3X23A 3FM8C 4TKNA 5DHAB 4MY6A 2RSGA 1BTNA 2HTHB 1WJMA 3NWAA 5D3VA 1KZGA 2RUKB 3HW2B 2M38A 1DYNA 3F5RA 2J0JA 1X11A 4EJNA 4HAVB 4A6FA 5CLLB 1ISNA 2ROZB 2DHKA 2N0YA 1WG7A 1X1FA 1J0WA 3P6AA 2DHJA 2KGXB 1ZYIA 5DI9B 2GJYA 3ML4A 4YL8A 1KZ7A 1W1DA 2GCLA 3A8PA 2D9YA 3PEGA 2ELBA 3PG7A 3A58A 4QJ5B 1Z87A 1MK9B 1MIXA 2Q13A 2UVMA 1U27A 1FB8A 1P6SA 3A8QA 2W2XD 1UNPA 2ROVA 1U2BA 3TCAA 3TW1A 2YRYA 1OY2A 4YONA 1J19A 1U5FA 5M4YB 3PZDA 2D11A 4GOUA 1SHCA 3PVWA 4GN1A 3PVLA 4CHJA 2LYDA 2COAA 3AJ4A 2L2IA 1V89A 5LG4B 2YT2A 1AWEA 4GXBA 2DKPA 3GYOA 4H8SA 2Z59A 4KHBB 2PZ1A 1I7AA 1ZC4B 1XR0B 4K2PA 4KAXB 3BINA 1H4RA 5GOWB 4NSWA 3KRXA 3PP2A 4EKUA 1Q67A 1DROA 4TYZA 3CIKA 3D8EA 4WVFB 2YF0A 4HHVA 1EVHA 3NWFA 1T77A 2UZRA 1KI1B 4Z2MB 2RNRB 3OHMB 2V76A 5KQ1A 2K2JA 1UPRA 1NTVA 3B77A 2N23A 2AL6A 2EC1A 5C79A 2K49A 4HAYB 4HAWB 3MDBC 1Y19B 3V5WA 4QJ4B 1FHXA 1OQNA 2YS5A 1XODA 1SGHA 4MK0A 3DCXA 5C6RA 2M14A 2OTXA 2VSZA 4KVGB 4OT1A 2D4QA 2MWNB 1ZC3B 3VOQA 3D8DA 3G9WA 4DXAB 5JHHA 5J3TA 5FI0A 2YVCA 2D2QA 2K8EA 1U5DA 1K5GB 5J3QA 2ZPYA 2LKOA 4K81A 3U12A 5DIFB 1P5TA 1DDWA 1FHWA 4Y94A 2J0KA 2L1CA 4DBBA 3AU4A 2QKLA 2I5FA 4HB2B 1M7EA 3O96A 4KHAA 2BCJA 2MKRA 3QBVB 3NSUA 5HE3A 4GNKB 1X1GA 1BAKA 4MT7A 3HSAA 3SNHA 2IFSA 2H7EA 2RGNB 5C5BB 1XKEA 4HDQA 1FGYA 2LG1A 1TJ6A 1U5GA 3KSYA 1MK7B 1PFJA 2K00A 4HB0B 5I2SA 1FGZA 3WA0A 2LOXA 4CYEA 4WSFA 4GZUA 3FSSA 2VKIA 1QQGA 3QIJA 2I1KA 1FOEA 1TQZA 3ODWA 4D6WA 1ZSQA 2KIEA 4P7IA 2JP2A 2Y8FA 5D3WA 4PNKA 3ODOA 1MKEA 1XX0A 1EAZA 2NZ8B 1V88A 4HSIA 3AU5A 3HQCA 3KY9A 5J3YA 2AEHA 2VRWB 1MAIA 2DTCA 2YS3A 4BBKA 2Z4DA 5D3XA 4A6FB 2P0DA 1LW3A 3NW8A 1NI2A 3M1IB 2KIGA 3DXCA 1GC7A 5HE1A 3U8ZA 2DX5A 3WYFB 2CY5A 3TO1A 4Z2NA 2J0MA 2HE7A 4F7GA 1MIZB 1UNRA 1N3HA 2DYQA 2R2YA 4IOYX 4A6KA 2NMBA 2K2UA 3ULCA 2UZSA 4HATB 2D9VA 1U29A 2KCJA 3SYXA 1P3RA 4GPTB 3U7DA 2I5CA 5DH9B 2OQBA 1EGXA 4F7HA 4HDOA 2DLWA 2CY4A 2CAYA 2RLOA 2ZKMX 3DXDA 5JP4A 2H7DA 2P0HA 1EF1A 1DBHA 3FEHA 3MPXA 2QKMA 1V5UA 1W1HA 1XCGA 4XWXA 1MI1A 5L81A 2LOZA 2XQNM 2DA0A 2IYBA 3UZTA 1H10A 2Z0PA 2MFQA 4ZRKA 3P7ZA 4HB3B 4PQ0A 2COCA 2RRFA 2EJ8A 3HIEA 3SUZA 2G35A 2J59M 2X18A 1WVHA 1RJ2A 4D0NB 5IRSA 1WI1A 2I1JA 1UNQA 2R09A 4CHMA 1U5EA 3NWDA 2Z0QA 2Z0OA 4QXAB 1FHOA 2DYNA 4DIXA 3KRWA 3BJIA 4K17A 1PLSA 5JLJB 5HE2A 2ADZA 2LULA 2DHIA 3ZDTA 2DFKA 5KCVA 4KHBA 4CSQA 3QWMA 2EMSA 3T06A 1OMWA 2FJLA 1NTYA 2EMTA 3TVVA 2D9XA 4OSNA 1WGQA 1V5MA 2E2XA 2CODA 4WJ7A 2KR0A 2YS1A 2W2XC 3A98B 3LJUX 5FI1A 2D10A 1PMSA 4ZRIA 1I2HA 2P0FA 4NY0A 4F7UP 1X86A 1LB1A 2D9ZA 2GCJA 4QJ3B 2COFA 5C16A 1XD4A 2NBVA 5I2MA 4EMOA 4L6EA 2Y8GA 3ULBA 4HB4B 2P8VA 4C0AA 3GYPA 4IAPA 2KUQA 3SO6A 2YSZA 3D8FA 2DKQA 4HAUB 3FVCA 1E5WA 3TFMA 1ZVRA 3KZ1A 3N7CA 1RRPB 1UEFA 4GMVA 4KHOA 3RCPA
chains in the Genus database with same CATH topology
1IRSA 3DXEA 3VIAA 5D3YA 2RVBB 4K2OA 2CRFA 3HK0A 5DHFB 3ODXA 2KUPA 1ZM0A 1V61A 4DX90 2DN6A 1DDVA 1MPHA 5D27A 2D9WA 4A6HA 1M7RA 1DDMA 1BWNA 5HE0A 1K5DB 3IVFA 4IFSA 2DX1A 1B55A 2YT0A 1X05A 3CXBB 1TXDA 1Y5OA 3PSCA 5C5BA 4DX8A 5CLQB 5KQ4A 5LOPB 2MDXA 1WGUA 2R0DA 1W1GA 4GMXB 1AQCA 4A5KA 3F0WA 2YT1A 5JHGA 1BTKA 1NU2A 3OANA 1WJ1A 2GS0A 4B6HA 3PVUA 2W2WA 1QC6A 1V5PA 4HAXB 1GC6A 1GG3A 2Y7BA 5EFXA 3ZVRA 1FAOA 1UPQA 4HAZB 4ZRJA 2ELAA 3SV1A 5LONB 3X23A 3FM8C 4TKNA 5DHAB 4MY6A 2RSGA 1BTNA 2HTHB 1WJMA 5D3VA 1KZGA 2RUKB 3HW2B 2M38A 1DYNA 3F5RA 2J0JA 1X11A 4EJNA 4HAVB 4A6FA 5CLLB 1ISNA 2ROZB 2DHKA 2N0YA 1WG7A 1X1FA 1J0WA 3P6AA 2DHJA 2KGXB 5DI9B 2GJYA 3ML4A 4YL8A 1KZ7A 1W1DA 2GCLA 3A8PA 2D9YA 3PEGA 2ELBA 3PG7A 1Z87A 1MK9B 1MIXA 2Q13A 2UVMA 1U27A 1FB8A 1P6SA 3A8QA 2W2XD 1UNPA 2ROVA 1U2BA 3TCAA 3TW1A 2YRYA 1OY2A 4YONA 1J19A 1U5FA 3PZDA 2D11A 1SHCA 3PVWA 4GN1A 3PVLA 4CHJA 2LYDA 2COAA 3AJ4A 2L2IA 1V89A 1AWEA 4GXBA 2DKPA 3GYOA 4H8SA 4KHBB 2PZ1A 1I7AA 1ZC4B 1XR0B 4K2PA 4KAXB 3BINA 1H4RA 5GOWB 4NSWA 3KRXA 3PP2A 4EKUA 1Q67A 1DROA 4TYZA 3CIKA 3D8EA 4WVFB 2YF0A 4HHVA 1EVHA 2UZRA 1KI1B 4Z2MB 2RNRB 2V76A 5KQ1A 2K2JA 1UPRA 1NTVA 2N23A 2AL6A 2EC1A 5C79A 4HAYB 4HAWB 3MDBC 1Y19B 3V5WA 1FHXA 1OQNA 2YS5A 1XODA 1SGHA 4MK0A 5C6RA 2M14A 2OTXA 2VSZA 4KVGB 2D4QA 2MWNB 1ZC3B 3VOQA 3D8DA 3G9WA 4DXAB 5JHHA 5J3TA 5FI0A 2YVCA 2D2QA 1U5DA 1K5GB 5J3QA 2ZPYA 2LKOA 4K81A 5DIFB 1P5TA 1DDWA 1FHWA 4Y94A 2J0KA 2L1CA 4DBBA 3AU4A 2QKLA 2I5FA 4HB2B 1M7EA 3O96A 4KHAA 2BCJA 2MKRA 3QBVB 3NSUA 5HE3A 1X1GA 1BAKA 4MT7A 3SNHA 2IFSA 2H7EA 2RGNB 5C5BB 1XKEA 4HDQA 1FGYA 2LG1A 1TJ6A 1U5GA 3KSYA 1MK7B 1PFJA 2K00A 4HB0B 1FGZA 3WA0A 2LOXA 4CYEA 4WSFA 4GZUA 3FSSA 2VKIA 1QQGA 3QIJA 2I1KA 1FOEA 1TQZA 3ODWA 1ZSQA 4P7IA 2JP2A 2Y8FA 5D3WA 4PNKA 3ODOA 1MKEA 1XX0A 1EAZA 2NZ8B 1V88A 3AU5A 3HQCA 3KY9A 5J3YA 2AEHA 2VRWB 1MAIA 2DTCA 2YS3A 4BBKA 5D3XA 4A6FB 2P0DA 1LW3A 1NI2A 3M1IB 3DXCA 1GC7A 5HE1A 3U8ZA 2DX5A 3WYFB 2CY5A 3TO1A 4Z2NA 2J0MA 2HE7A 4F7GA 1MIZB 1UNRA 1N3HA 2DYQA 4IOYX 4A6KA 2NMBA 2K2UA 3ULCA 2UZSA 4HATB 2D9VA 1U29A 2KCJA 3SYXA 1P3RA 4GPTB 3U7DA 2I5CA 5DH9B 2OQBA 1EGXA 4F7HA 4HDOA 2DLWA 2CY4A 2CAYA 2RLOA 3DXDA 5JP4A 2H7DA 2P0HA 1EF1A 1DBHA 3FEHA 3MPXA 2QKMA 1V5UA 1W1HA 1XCGA 4XWXA 5L81A 2LOZA 2XQNM 2DA0A 2IYBA 3UZTA 1H10A 2Z0PA 2MFQA 4ZRKA 3P7ZA 4HB3B 4PQ0A 2COCA 2EJ8A 3SUZA 2G35A 2J59M 2X18A 1WVHA 1RJ2A 4D0NB 1WI1A 2I1JA 1UNQA 2R09A 4CHMA 1U5EA 2Z0QA 2Z0OA 1FHOA 2DYNA 3KRWA 3BJIA 4K17A 1PLSA 5JLJB 5HE2A 2ADZA 2LULA 2DHIA 3ZDTA 2DFKA 5KCVA 3QWMA 2EMSA 3T06A 1OMWA 2FJLA 1NTYA 2EMTA 3TVVA 2D9XA 1WGQA 1V5MA 2E2XA 2CODA 4WJ7A 2YS1A 2W2XC 3A98B 3LJUX 5FI1A 2D10A 1PMSA 4ZRIA 1I2HA 2P0FA 4NY0A 4F7UP 1X86A 1LB1A 2D9ZA 2GCJA 2COFA 5C16A 1XD4A 4EMOA 4L6EA 2Y8GA 3ULBA 4HB4B 2P8VA 4C0AA 3GYPA 4IAPA 3SO6A 2YSZA 3D8FA 2DKQA 4HAUB 1E5WA 3TFMA 1ZVRA 3KZ1A 3N7CA 1RRPB 1UEFA 4GMVA 4KHOA 3RCPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IRS A;  3DXE A;  3VIA A;  5D3Y A;  2RVB B;  4K2O A;  2CRF A;  3HK0 A;  5DHF B;  3ODX A;  2KUP A;  1ZM0 A;  1V61 A;  4DX9 0;  2DN6 A;  1DDV A;  1MPH A;  5D27 A;  2D9W A;  4A6H A;  1M7R A;  1DDM A;  1BWN A;  5HE0 A;  1K5D B;  3IVF A;  4IFS A;  2DX1 A;  1B55 A;  2YT0 A;  1X05 A;  3CXB B;  1TXD A;  1Y5O A;  3PSC A;  5C5B A;  4DX8 A;  5CLQ B;  5KQ4 A;  5LOP B;  2MDX A;  1WGU A;  2R0D A;  1W1G A;  4GMX B;  1AQC A;  4A5K A;  3F0W A;  2YT1 A;  5JHG A;  1BTK A;  1NU2 A;  3OAN A;  1WJ1 A;  2GS0 A;  4B6H A;  3PVU A;  2W2W A;  1QC6 A;  1V5P A;  4HAX B;  1GC6 A;  1GG3 A;  2Y7B A;  5EFX A;  3ZVR A;  1FAO A;  1UPQ A;  4HAZ B;  4ZRJ A;  2ELA A;  3SV1 A;  5LON B;  3X23 A;  3FM8 C;  4TKN A;  5DHA B;  4MY6 A;  2RSG A;  1BTN A;  2HTH B;  1WJM A;  5D3V A;  1KZG A;  2RUK B;  3HW2 B;  2M38 A;  1DYN A;  3F5R A;  2J0J A;  1X11 A;  4EJN A;  4HAV B;  4A6F A;  5CLL B;  1ISN A;  2ROZ B;  2DHK A;  2N0Y A;  1WG7 A;  1X1F A;  1J0W A;  3P6A A;  2DHJ A;  2KGX B;  5DI9 B;  2GJY A;  3ML4 A;  4YL8 A;  1KZ7 A;  1W1D A;  2GCL A;  3A8P A;  2D9Y A;  3PEG A;  2ELB A;  3PG7 A;  1Z87 A;  1MK9 B;  1MIX A;  2Q13 A;  2UVM A;  1U27 A;  1FB8 A;  1P6S A;  3A8Q A;  2W2X D;  1UNP A;  2ROV A;  1U2B A;  3TCA A;  3TW1 A;  2YRY A;  1OY2 A;  4YON A;  1J19 A;  1U5F A;  3PZD A;  2D11 A;  1SHC A;  3PVW A;  4GN1 A;  3PVL A;  4CHJ A;  2LYD A;  2COA A;  3AJ4 A;  2L2I A;  1V89 A;  1AWE A;  4GXB A;  2DKP A;  3GYO A;  4H8S A;  4KHB B;  2PZ1 A;  1I7A A;  1ZC4 B;  1XR0 B;  4K2P A;  4KAX B;  3BIN A;  1H4R A;  5GOW B;  4NSW A;  3KRX A;  3PP2 A;  4EKU A;  1Q67 A;  1DRO A;  4TYZ A;  3CIK A;  3D8E A;  4WVF B;  2YF0 A;  4HHV A;  1EVH A;  2UZR A;  1KI1 B;  4Z2M B;  2RNR B;  2V76 A;  5KQ1 A;  2K2J A;  1UPR A;  1NTV A;  2N23 A;  2AL6 A;  2EC1 A;  5C79 A;  4HAY B;  4HAW B;  3MDB C;  1Y19 B;  3V5W A;  1FHX A;  1OQN A;  2YS5 A;  1XOD A;  1SGH A;  4MK0 A;  5C6R A;  2M14 A;  2OTX A;  2VSZ A;  4KVG B;  2D4Q A;  2MWN B;  1ZC3 B;  3VOQ A;  3D8D A;  3G9W A;  4DXA B;  5JHH A;  5J3T A;  5FI0 A;  2YVC A;  2D2Q A;  1U5D A;  1K5G B;  5J3Q A;  2ZPY A;  2LKO A;  4K81 A;  5DIF B;  1P5T A;  1DDW A;  1FHW A;  4Y94 A;  2J0K A;  2L1C A;  4DBB A;  3AU4 A;  2QKL A;  2I5F A;  4HB2 B;  1M7E A;  3O96 A;  4KHA A;  2BCJ A;  2MKR A;  3QBV B;  3NSU A;  5HE3 A;  1X1G A;  1BAK A;  4MT7 A;  3SNH A;  2IFS A;  2H7E A;  2RGN B;  5C5B B;  1XKE A;  4HDQ A;  1FGY A;  2LG1 A;  1TJ6 A;  1U5G A;  3KSY A;  1MK7 B;  1PFJ A;  2K00 A;  4HB0 B;  1FGZ A;  3WA0 A;  2LOX A;  4CYE A;  4WSF A;  4GZU A;  3FSS A;  2VKI A;  1QQG A;  3QIJ A;  2I1K A;  1FOE A;  1TQZ A;  3ODW A;  1ZSQ A;  4P7I A;  2JP2 A;  2Y8F A;  5D3W A;  4PNK A;  3ODO A;  1MKE A;  1XX0 A;  1EAZ A;  2NZ8 B;  1V88 A;  3AU5 A;  3HQC A;  3KY9 A;  5J3Y A;  2AEH A;  2VRW B;  1MAI A;  2DTC A;  2YS3 A;  4BBK A;  5D3X A;  4A6F B;  2P0D A;  1LW3 A;  1NI2 A;  3M1I B;  3DXC A;  1GC7 A;  5HE1 A;  3U8Z A;  2DX5 A;  3WYF B;  2CY5 A;  3TO1 A;  4Z2N A;  2J0M A;  2HE7 A;  4F7G A;  1MIZ B;  1UNR A;  1N3H A;  2DYQ A;  4IOY X;  4A6K A;  2NMB A;  2K2U A;  3ULC A;  2UZS A;  4HAT B;  2D9V A;  1U29 A;  2KCJ A;  3SYX A;  1P3R A;  4GPT B;  3U7D A;  2I5C A;  5DH9 B;  2OQB A;  1EGX A;  4F7H A;  4HDO A;  2DLW A;  2CY4 A;  2CAY A;  2RLO A;  3DXD A;  5JP4 A;  2H7D A;  2P0H A;  1EF1 A;  1DBH A;  3FEH A;  3MPX A;  2QKM A;  1V5U A;  1W1H A;  1XCG A;  4XWX A;  5L81 A;  2LOZ A;  2XQN M;  2DA0 A;  2IYB A;  3UZT A;  1H10 A;  2Z0P A;  2MFQ A;  4ZRK A;  3P7Z A;  4HB3 B;  4PQ0 A;  2COC A;  2EJ8 A;  3SUZ A;  2G35 A;  2J59 M;  2X18 A;  1WVH A;  1RJ2 A;  4D0N B;  1WI1 A;  2I1J A;  1UNQ A;  2R09 A;  4CHM A;  1U5E A;  2Z0Q A;  2Z0O A;  1FHO A;  2DYN A;  3KRW A;  3BJI A;  4K17 A;  1PLS A;  5JLJ B;  5HE2 A;  2ADZ A;  2LUL A;  2DHI A;  3ZDT A;  2DFK A;  5KCV A;  3QWM A;  2EMS A;  3T06 A;  1OMW A;  2FJL A;  1NTY A;  2EMT A;  3TVV A;  2D9X A;  1WGQ A;  1V5M A;  2E2X A;  2COD A;  4WJ7 A;  2YS1 A;  2W2X C;  3A98 B;  3LJU X;  5FI1 A;  2D10 A;  1PMS A;  4ZRI A;  1I2H A;  2P0F A;  4NY0 A;  4F7U P;  1X86 A;  1LB1 A;  2D9Z A;  2GCJ A;  2COF A;  5C16 A;  1XD4 A;  4EMO A;  4L6E A;  2Y8G A;  3ULB A;  4HB4 B;  2P8V A;  4C0A A;  3GYP A;  4IAP A;  3SO6 A;  2YSZ A;  3D8F A;  2DKQ A;  4HAU B;  1E5W A;  3TFM A;  1ZVR A;  3KZ1 A;  3N7C A;  1RRP B;  1UEF A;  4GMV A;  4KHO A;  3RCP A; 
#chains in the Genus database with same CATH topology
 1IRS A;  3DXE A;  3VIA A;  5D3Y A;  2RVB B;  4K2O A;  2CRF A;  3HK0 A;  5DHF B;  3ODX A;  2KUP A;  1ZM0 A;  1V61 A;  4DX9 0;  2DN6 A;  1DDV A;  1MPH A;  2GUM A;  5D27 A;  2D9W A;  4A6H A;  1M7R A;  1DDM A;  1BWN A;  5HE0 A;  1K5D B;  3IVF A;  4IFS A;  2DX1 A;  1B55 A;  2YT0 A;  1X05 A;  2Z13 A;  3CXB B;  1TXD A;  1Y5O A;  3PSC A;  5C5B A;  4DX8 A;  2FJU B;  5CLQ B;  5KQ4 A;  5LOP B;  2Z14 A;  2MDX A;  1WGU A;  2R0D A;  1W1G A;  4GMX B;  1AQC A;  4A5K A;  3F0W A;  2YT1 A;  5JHG A;  1BTK A;  1NU2 A;  3OAN A;  1WJ1 A;  2GS0 A;  4B6H A;  4L1R A;  3PVU A;  2W2W A;  1QC6 A;  1V5P A;  4HAX B;  1GC6 A;  1GG3 A;  2Y7B A;  5EFX A;  3ZVR A;  1FAO A;  1UPQ A;  4HAZ B;  4ZRJ A;  2ELA A;  3SV1 A;  5LON B;  3X23 A;  3FM8 C;  4TKN A;  5DHA B;  4MY6 A;  2RSG A;  1BTN A;  2HTH B;  1WJM A;  3NWA A;  5D3V A;  1KZG A;  2RUK B;  3HW2 B;  2M38 A;  1DYN A;  3F5R A;  2J0J A;  1X11 A;  4EJN A;  4HAV B;  4A6F A;  5CLL B;  1ISN A;  2ROZ B;  2DHK A;  2N0Y A;  1WG7 A;  1X1F A;  1J0W A;  3P6A A;  2DHJ A;  2KGX B;  1ZYI A;  5DI9 B;  2GJY A;  3ML4 A;  4YL8 A;  1KZ7 A;  1W1D A;  2GCL A;  3A8P A;  2D9Y A;  3PEG A;  2ELB A;  3PG7 A;  3A58 A;  4QJ5 B;  1Z87 A;  1MK9 B;  1MIX A;  2Q13 A;  2UVM A;  1U27 A;  1FB8 A;  1P6S A;  3A8Q A;  2W2X D;  1UNP A;  2ROV A;  1U2B A;  3TCA A;  3TW1 A;  2YRY A;  1OY2 A;  4YON A;  1J19 A;  1U5F A;  5M4Y B;  3PZD A;  2D11 A;  4GOU A;  1SHC A;  3PVW A;  4GN1 A;  3PVL A;  4CHJ A;  2LYD A;  2COA A;  3AJ4 A;  2L2I A;  1V89 A;  5LG4 B;  2YT2 A;  1AWE A;  4GXB A;  2DKP A;  3GYO A;  4H8S A;  2Z59 A;  4KHB B;  2PZ1 A;  1I7A A;  1ZC4 B;  1XR0 B;  4K2P A;  4KAX B;  3BIN A;  1H4R A;  5GOW B;  4NSW A;  3KRX A;  3PP2 A;  4EKU A;  1Q67 A;  1DRO A;  4TYZ A;  3CIK A;  3D8E A;  4WVF B;  2YF0 A;  4HHV A;  1EVH A;  3NWF A;  1T77 A;  2UZR A;  1KI1 B;  4Z2M B;  2RNR B;  3OHM B;  2V76 A;  5KQ1 A;  2K2J A;  1UPR A;  1NTV A;  3B77 A;  2N23 A;  2AL6 A;  2EC1 A;  5C79 A;  2K49 A;  4HAY B;  4HAW B;  3MDB C;  1Y19 B;  3V5W A;  4QJ4 B;  1FHX A;  1OQN A;  2YS5 A;  1XOD A;  1SGH A;  4MK0 A;  3DCX A;  5C6R A;  2M14 A;  2OTX A;  2VSZ A;  4KVG B;  4OT1 A;  2D4Q A;  2MWN B;  1ZC3 B;  3VOQ A;  3D8D A;  3G9W A;  4DXA B;  5JHH A;  5J3T A;  5FI0 A;  2YVC A;  2D2Q A;  2K8E A;  1U5D A;  1K5G B;  5J3Q A;  2ZPY A;  2LKO A;  4K81 A;  3U12 A;  5DIF B;  1P5T A;  1DDW A;  1FHW A;  4Y94 A;  2J0K A;  2L1C A;  4DBB A;  3AU4 A;  2QKL A;  2I5F A;  4HB2 B;  1M7E A;  3O96 A;  4KHA A;  2BCJ A;  2MKR A;  3QBV B;  3NSU A;  5HE3 A;  4GNK B;  1X1G A;  1BAK A;  4MT7 A;  3HSA A;  3SNH A;  2IFS A;  2H7E A;  2RGN B;  5C5B B;  1XKE A;  4HDQ A;  1FGY A;  2LG1 A;  1TJ6 A;  1U5G A;  3KSY A;  1MK7 B;  1PFJ A;  2K00 A;  4HB0 B;  5I2S A;  1FGZ A;  3WA0 A;  2LOX A;  4CYE A;  4WSF A;  4GZU A;  3FSS A;  2VKI A;  1QQG A;  3QIJ A;  2I1K A;  1FOE A;  1TQZ A;  3ODW A;  4D6W A;  1ZSQ A;  2KIE A;  4P7I A;  2JP2 A;  2Y8F A;  5D3W A;  4PNK A;  3ODO A;  1MKE A;  1XX0 A;  1EAZ A;  2NZ8 B;  1V88 A;  4HSI A;  3AU5 A;  3HQC A;  3KY9 A;  5J3Y A;  2AEH A;  2VRW B;  1MAI A;  2DTC A;  2YS3 A;  4BBK A;  2Z4D A;  5D3X A;  4A6F B;  2P0D A;  1LW3 A;  3NW8 A;  1NI2 A;  3M1I B;  2KIG A;  3DXC A;  1GC7 A;  5HE1 A;  3U8Z A;  2DX5 A;  3WYF B;  2CY5 A;  3TO1 A;  4Z2N A;  2J0M A;  2HE7 A;  4F7G A;  1MIZ B;  1UNR A;  1N3H A;  2DYQ A;  2R2Y A;  4IOY X;  4A6K A;  2NMB A;  2K2U A;  3ULC A;  2UZS A;  4HAT B;  2D9V A;  1U29 A;  2KCJ A;  3SYX A;  1P3R A;  4GPT B;  3U7D A;  2I5C A;  5DH9 B;  2OQB A;  1EGX A;  4F7H A;  4HDO A;  2DLW A;  2CY4 A;  2CAY A;  2RLO A;  2ZKM X;  3DXD A;  5JP4 A;  2H7D A;  2P0H A;  1EF1 A;  1DBH A;  3FEH A;  3MPX A;  2QKM A;  1V5U A;  1W1H A;  1XCG A;  4XWX A;  1MI1 A;  5L81 A;  2LOZ A;  2XQN M;  2DA0 A;  2IYB A;  3UZT A;  1H10 A;  2Z0P A;  2MFQ A;  4ZRK A;  3P7Z A;  4HB3 B;  4PQ0 A;  2COC A;  2RRF A;  2EJ8 A;  3HIE A;  3SUZ A;  2G35 A;  2J59 M;  2X18 A;  1WVH A;  1RJ2 A;  4D0N B;  5IRS A;  1WI1 A;  2I1J A;  1UNQ A;  2R09 A;  4CHM A;  1U5E A;  3NWD A;  2Z0Q A;  2Z0O A;  4QXA B;  1FHO A;  2DYN A;  4DIX A;  3KRW A;  3BJI A;  4K17 A;  1PLS A;  5JLJ B;  5HE2 A;  2ADZ A;  2LUL A;  2DHI A;  3ZDT A;  2DFK A;  5KCV A;  4KHB A;  4CSQ A;  3QWM A;  2EMS A;  3T06 A;  1OMW A;  2FJL A;  1NTY A;  2EMT A;  3TVV A;  2D9X A;  4OSN A;  1WGQ A;  1V5M A;  2E2X A;  2COD A;  4WJ7 A;  2KR0 A;  2YS1 A;  2W2X C;  3A98 B;  3LJU X;  5FI1 A;  2D10 A;  1PMS A;  4ZRI A;  1I2H A;  2P0F A;  4NY0 A;  4F7U P;  1X86 A;  1LB1 A;  2D9Z A;  2GCJ A;  4QJ3 B;  2COF A;  5C16 A;  1XD4 A;  2NBV A;  5I2M A;  4EMO A;  4L6E A;  2Y8G A;  3ULB A;  4HB4 B;  2P8V A;  4C0A A;  3GYP A;  4IAP A;  2KUQ A;  3SO6 A;  2YSZ A;  3D8F A;  2DKQ A;  4HAU B;  3FVC A;  1E5W A;  3TFM A;  1ZVR A;  3KZ1 A;  3N7C A;  1RRP B;  1UEF A;  4GMV A;  4KHO A;  3RCP A; 
#chains in the Genus database with same CATH homology
 1IRS A;  3DXE A;  3VIA A;  5D3Y A;  2RVB B;  4K2O A;  2CRF A;  3HK0 A;  5DHF B;  3ODX A;  2KUP A;  1ZM0 A;  1V61 A;  4DX9 0;  2DN6 A;  1DDV A;  1MPH A;  5D27 A;  2D9W A;  4A6H A;  1M7R A;  1DDM A;  1BWN A;  5HE0 A;  1K5D B;  3IVF A;  4IFS A;  2DX1 A;  1B55 A;  2YT0 A;  1X05 A;  3CXB B;  1TXD A;  1Y5O A;  3PSC A;  5C5B A;  4DX8 A;  5CLQ B;  5KQ4 A;  5LOP B;  2MDX A;  1WGU A;  2R0D A;  1W1G A;  4GMX B;  1AQC A;  4A5K A;  3F0W A;  2YT1 A;  5JHG A;  1BTK A;  1NU2 A;  3OAN A;  1WJ1 A;  2GS0 A;  4B6H A;  3PVU A;  2W2W A;  1QC6 A;  1V5P A;  4HAX B;  1GC6 A;  1GG3 A;  2Y7B A;  5EFX A;  3ZVR A;  1FAO A;  1UPQ A;  4HAZ B;  4ZRJ A;  2ELA A;  3SV1 A;  5LON B;  3X23 A;  3FM8 C;  4TKN A;  5DHA B;  4MY6 A;  2RSG A;  1BTN A;  2HTH B;  1WJM A;  5D3V A;  1KZG A;  2RUK B;  3HW2 B;  2M38 A;  1DYN A;  3F5R A;  2J0J A;  1X11 A;  4EJN A;  4HAV B;  4A6F A;  5CLL B;  1ISN A;  2ROZ B;  2DHK A;  2N0Y A;  1WG7 A;  1X1F A;  1J0W A;  3P6A A;  2DHJ A;  2KGX B;  5DI9 B;  2GJY A;  3ML4 A;  4YL8 A;  1KZ7 A;  1W1D A;  2GCL A;  3A8P A;  2D9Y A;  3PEG A;  2ELB A;  3PG7 A;  1Z87 A;  1MK9 B;  1MIX A;  2Q13 A;  2UVM A;  1U27 A;  1FB8 A;  1P6S A;  3A8Q A;  2W2X D;  1UNP A;  2ROV A;  1U2B A;  3TCA A;  3TW1 A;  2YRY A;  1OY2 A;  4YON A;  1J19 A;  1U5F A;  3PZD A;  2D11 A;  1SHC A;  3PVW A;  4GN1 A;  3PVL A;  4CHJ A;  2LYD A;  2COA A;  3AJ4 A;  2L2I A;  1V89 A;  1AWE A;  4GXB A;  2DKP A;  3GYO A;  4H8S A;  4KHB B;  2PZ1 A;  1I7A A;  1ZC4 B;  1XR0 B;  4K2P A;  4KAX B;  3BIN A;  1H4R A;  5GOW B;  4NSW A;  3KRX A;  3PP2 A;  4EKU A;  1Q67 A;  1DRO A;  4TYZ A;  3CIK A;  3D8E A;  4WVF B;  2YF0 A;  4HHV A;  1EVH A;  2UZR A;  1KI1 B;  4Z2M B;  2RNR B;  2V76 A;  5KQ1 A;  2K2J A;  1UPR A;  1NTV A;  2N23 A;  2AL6 A;  2EC1 A;  5C79 A;  4HAY B;  4HAW B;  3MDB C;  1Y19 B;  3V5W A;  1FHX A;  1OQN A;  2YS5 A;  1XOD A;  1SGH A;  4MK0 A;  5C6R A;  2M14 A;  2OTX A;  2VSZ A;  4KVG B;  2D4Q A;  2MWN B;  1ZC3 B;  3VOQ A;  3D8D A;  3G9W A;  4DXA B;  5JHH A;  5J3T A;  5FI0 A;  2YVC A;  2D2Q A;  1U5D A;  1K5G B;  5J3Q A;  2ZPY A;  2LKO A;  4K81 A;  5DIF B;  1P5T A;  1DDW A;  1FHW A;  4Y94 A;  2J0K A;  2L1C A;  4DBB A;  3AU4 A;  2QKL A;  2I5F A;  4HB2 B;  1M7E A;  3O96 A;  4KHA A;  2BCJ A;  2MKR A;  3QBV B;  3NSU A;  5HE3 A;  1X1G A;  1BAK A;  4MT7 A;  3SNH A;  2IFS A;  2H7E A;  2RGN B;  5C5B B;  1XKE A;  4HDQ A;  1FGY A;  2LG1 A;  1TJ6 A;  1U5G A;  3KSY A;  1MK7 B;  1PFJ A;  2K00 A;  4HB0 B;  1FGZ A;  3WA0 A;  2LOX A;  4CYE A;  4WSF A;  4GZU A;  3FSS A;  2VKI A;  1QQG A;  3QIJ A;  2I1K A;  1FOE A;  1TQZ A;  3ODW A;  1ZSQ A;  4P7I A;  2JP2 A;  2Y8F A;  5D3W A;  4PNK A;  3ODO A;  1MKE A;  1XX0 A;  1EAZ A;  2NZ8 B;  1V88 A;  3AU5 A;  3HQC A;  3KY9 A;  5J3Y A;  2AEH A;  2VRW B;  1MAI A;  2DTC A;  2YS3 A;  4BBK A;  5D3X A;  4A6F B;  2P0D A;  1LW3 A;  1NI2 A;  3M1I B;  3DXC A;  1GC7 A;  5HE1 A;  3U8Z A;  2DX5 A;  3WYF B;  2CY5 A;  3TO1 A;  4Z2N A;  2J0M A;  2HE7 A;  4F7G A;  1MIZ B;  1UNR A;  1N3H A;  2DYQ A;  4IOY X;  4A6K A;  2NMB A;  2K2U A;  3ULC A;  2UZS A;  4HAT B;  2D9V A;  1U29 A;  2KCJ A;  3SYX A;  1P3R A;  4GPT B;  3U7D A;  2I5C A;  5DH9 B;  2OQB A;  1EGX A;  4F7H A;  4HDO A;  2DLW A;  2CY4 A;  2CAY A;  2RLO A;  3DXD A;  5JP4 A;  2H7D A;  2P0H A;  1EF1 A;  1DBH A;  3FEH A;  3MPX A;  2QKM A;  1V5U A;  1W1H A;  1XCG A;  4XWX A;  5L81 A;  2LOZ A;  2XQN M;  2DA0 A;  2IYB A;  3UZT A;  1H10 A;  2Z0P A;  2MFQ A;  4ZRK A;  3P7Z A;  4HB3 B;  4PQ0 A;  2COC A;  2EJ8 A;  3SUZ A;  2G35 A;  2J59 M;  2X18 A;  1WVH A;  1RJ2 A;  4D0N B;  1WI1 A;  2I1J A;  1UNQ A;  2R09 A;  4CHM A;  1U5E A;  2Z0Q A;  2Z0O A;  1FHO A;  2DYN A;  3KRW A;  3BJI A;  4K17 A;  1PLS A;  5JLJ B;  5HE2 A;  2ADZ A;  2LUL A;  2DHI A;  3ZDT A;  2DFK A;  5KCV A;  3QWM A;  2EMS A;  3T06 A;  1OMW A;  2FJL A;  1NTY A;  2EMT A;  3TVV A;  2D9X A;  1WGQ A;  1V5M A;  2E2X A;  2COD A;  4WJ7 A;  2YS1 A;  2W2X C;  3A98 B;  3LJU X;  5FI1 A;  2D10 A;  1PMS A;  4ZRI A;  1I2H A;  2P0F A;  4NY0 A;  4F7U P;  1X86 A;  1LB1 A;  2D9Z A;  2GCJ A;  2COF A;  5C16 A;  1XD4 A;  4EMO A;  4L6E A;  2Y8G A;  3ULB A;  4HB4 B;  2P8V A;  4C0A A;  3GYP A;  4IAP A;  3SO6 A;  2YSZ A;  3D8F A;  2DKQ A;  4HAU B;  1E5W A;  3TFM A;  1ZVR A;  3KZ1 A;  3N7C A;  1RRP B;  1UEF A;  4GMV A;  4KHO A;  3RCP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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