1H10A

High resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to ins(1,3,4,5)-tetrakisphophate
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
117
structure length
117
Chain Sequence
SMSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords RAC-ALPHA SERINE/THREONINE KINASE
publication title High Resolution Structure of the Pleckstrin Homology Domain of Protein Kinase B/Akt Bound to Phosphatidylinositol (3,4,5)-Trisphosphate
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 29
structure length 117
sequence length 117
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2002-07-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1h10A00
2OQBA 3SYXA 4HAVB 2MWNB 5C79A 2YSZA 1U5FA 1XX0A 5GOWB 4C0AA 1DYNA 5C5BB 1J19A 5DHFB 3NSUA 2GCLA 2LULA 2AL6A 5CLLB 1RJ2A 5D3WA 5DI9B 2YRYA 4BBKA 2KCJA 4GPTB 1V5MA 2ROZB 1B55A 2J59M 4HAXB 3TFMA 1EF1A 4MK0A 4DX90 1FOEA 2HTHB 3P6AA 1U5DA 1NTVA 3PVUA 3U8ZA 1WGQA 1WJ1A 4GZUA 1P5TA 2LG1A 1FB8A 4HAYB 4A6HA 2N23A 3FM8C 2P0FA 3MDBC 2UZSA 4HATB 5KQ1A 2P0DA 2GCJA 3LJUX 5D3YA 5J3YA 3ODWA 5LONB 1MPHA 2COCA 1UNRA 2XQNM 3KSYA 2DHJA 3A98B 1FGZA 3O96A 2UVMA 2VKIA 3IVFA 1EAZA 1FHXA 1Z87A 3PVLA 2M38A 4CHJA 2K00A 2D10A 2KUPA 1M7EA 3WYFB 2MKRA 1BWNA 3T06A 3FSSA 2DFKA 1EVHA 1V61A 2QKLA 1M7RA 4GMXB 3PVWA 3ULBA 5LOPB 4YONA 2N0YA 2DN6A 4EKUA 1DDVA 3CIKA 3ULCA 2YS1A 3PG7A 1X05A 1IRSA 2BCJA 2ZPYA 2L1CA 2CAYA 2G35A 1ISNA 4P7IA 1FHWA 2D4QA 2M14A 4CYEA 1MKEA 2ELAA 5JLJB 4A5KA 1MIXA 2I5CA 4KHOA 3SV1A 2I1JA 2DKQA 3PEGA 2COFA 1OY2A 2IFSA 2DHKA 1XKEA 3U7DA 2P0HA 3FEHA 4EJNA 1PLSA 1P6SA 1W1HA 1NTYA 5D3VA 1WJMA 1ZSQA 4ZRJA 1DDWA 3WA0A 3D8DA 4CHMA 1XD4A 2ELBA 2W2XD 1QQGA 1TJ6A 1FHOA 3TO1A 2H7DA 3AU5A 1H4RA 1PFJA 1TXDA 3GYOA 4HAZB 1K5DB 2Q13A 1XR0B 3TCAA 2YVCA 3KY9A 1NI2A 2X18A 5HE1A 1Y19B 2RNRB 2Z0QA 4H8SA 1J0WA 5C6RA 3GYPA 4IFSA 3F5RA 4L6EA 5KCVA 1X86A 3QIJA 3HQCA 5KQ4A 2PZ1A 1I2HA 1LW3A 3TW1A 2EMSA 1BAKA 2YS5A 4GMVA 4HAWB 2LKOA 4KAXB 2Y7BA 1QC6A 2DX1A 2NZ8B 5EFXA 5HE0A 1WVHA 1ZC3B 4EMOA 4F7GA 3UZTA 4NY0A 2ROVA 1XODA 3QBVB 1OQNA 2H7EA 2OTXA 2HE7A 5D3XA 3A8QA 2GJYA 2UZRA 4A6FA 4B6HA 5HE2A 3KRWA 1DBHA 3PP2A 5DHAB 1KI1B 3D8EA 4A6KA 4K2OA 4K81A 4ZRKA 1GC6A 1KZGA 1ZVRA 2L2IA 2JP2A 3AJ4A 2RLOA 4GN1A 2YS3A 1U5EA 2DYQA 1MAIA 2FJLA 4HHVA 2YT0A 2D9YA 2I1KA 2Y8FA 2VSZA 2QKMA 4HDQA 1DROA 1W1GA 1MIZB 3RCPA 4HDOA 3KRXA 1FGYA 4HB3B 4IAPA 4HB0B 1U2BA 2YT1A 3G9WA 3SO6A 5JP4A 1X11A 2Z0PA 2DKPA 2LOXA 1BTNA 2W2WA 4XWXA 4Y94A 5DH9B 1UNPA 2D11A 4Z2NA 3VIAA 5DIFB 2K2JA 4WSFA 2R0DA 4KVGB 2RGNB 2NMBA 1X1FA 2DHIA 1U5GA 1X1GA 5L81A 3A8PA 5FI0A 4DX8A 4D0NB 5FI1A 3ZDTA 1WGUA 3ML4A 5J3TA 2J0JA 1SHCA 1ZM0A 1H10A 3D8FA 3OANA 1XCGA 2V76A 2COAA 1ZC4B 4K17A 2Y8GA 2I5FA 1OMWA 1W1DA 1U29A 1LB1A 3ODOA 4MY6A 2DTCA 2LOZA 4HB2B 2R09A 2DX5A 3TVVA 2IYBA 1I7AA 1V89A 1GC7A 3ODXA 4KHAA 1V5UA 2D9XA 4KHBB 2DLWA 3SNHA 4A6FB 3CXBB 2J0MA 1NU2A 4HAUB 5C5BA 4NSWA 2AEHA 4HB4B 2D2QA 3X23A 4TYZA 3ZVRA 1BTKA 2CY5A 4PNKA 4YL8A 1P3RA 2DYNA 1FAOA 1Y5OA 2RUKB 3SUZA 4GXBA 1Q67A 3AU4A 3PSCA 4F7HA 2E2XA 1UEFA 1AQCA 4F7UP 3HK0A 3P7ZA 1MK9B 1UPQA 5JHGA 1U27A 1PMSA 1MK7B 2YF0A 3F0WA 4WVFB 1UNQA 2CRFA 2EC1A 2ADZA 2Z0OA 2RVBB 5C16A 4ZRIA 1DDMA 5JHHA 4DXAB 1EGXA 1V5PA 3MPXA 2EMTA 1KZ7A 1TQZA 4PQ0A 3DXCA 4IOYX 2EJ8A 5HE3A 3M1IB 2GS0A 2MFQA 3BJIA 4TKNA 2CY4A 5D27A 2K2UA 2CODA 3BINA 1AWEA 4Z2MB 3DXDA 2LYDA 4MT7A 1UPRA 5J3QA 2VRWB 1SGHA 2RSGA 3HW2B 4WJ7A 3V5WA 3VOQA 2KGXB 2MDXA 1WG7A 4DBBA 2DA0A 3N7CA 1RRPB 1WI1A 3KZ1A 1V88A 1K5GB 2D9ZA 2J0KA 3PZDA 5CLQB 2W2XC 3QWMA 2D9VA 3DXEA 2P8VA 1N3HA 4K2PA 2D9WA 1E5WA 1GG3A
chains in the Genus database with same CATH superfamily
2OQBA 3SYXA 4HAVB 2MWNB 5C79A 2YSZA 1U5FA 1XX0A 5GOWB 4C0AA 1DYNA 1T77A 5C5BB 1J19A 5DHFB 3NSUA 2GCLA 2NBVA 2LULA 2AL6A 5CLLB 1RJ2A 5D3WA 5DI9B 2YRYA 4BBKA 2KCJA 4GPTB 1V5MA 2ROZB 1B55A 3NW8A 2J59M 4HAXB 3TFMA 1EF1A 4OSNA 4MK0A 4DX90 1FOEA 3OHMB 2HTHB 3P6AA 1U5DA 1NTVA 3PVUA 3U8ZA 1WGQA 4GOUA 1WJ1A 4GZUA 1P5TA 4DIXA 2KIGA 2LG1A 1FB8A 4HAYB 4A6HA 2N23A 3FM8C 2P0FA 3MDBC 2UZSA 4HATB 5KQ1A 2P0DA 2GCJA 3LJUX 5D3YA 5J3YA 3ODWA 5LONB 1MPHA 2COCA 1UNRA 3U12A 2XQNM 3KSYA 2DHJA 3A98B 1FGZA 3O96A 5I2SA 2UVMA 2VKIA 3IVFA 1EAZA 1FHXA 1Z87A 3PVLA 2M38A 4CHJA 2K00A 2RRFA 5LG4B 2D10A 2KUPA 1M7EA 3WYFB 2MKRA 1BWNA 3T06A 3FSSA 2DFKA 1EVHA 1V61A 2QKLA 1M7RA 4GMXB 3PVWA 3ULBA 5LOPB 4YONA 2N0YA 4QXAB 2DN6A 4EKUA 1DDVA 3CIKA 4D6WA 3ULCA 2YS1A 3PG7A 1X05A 1IRSA 2BCJA 2ZPYA 2L1CA 2CAYA 2G35A 4L1RA 1ISNA 4P7IA 1FHWA 2D4QA 2M14A 3DCXA 4CYEA 1MKEA 2ELAA 5JLJB 4A5KA 1MIXA 2I5CA 2Z13A 4KHOA 3SV1A 2I1JA 2DKQA 3PEGA 2COFA 1OY2A 3NWFA 2IFSA 2DHKA 1XKEA 3U7DA 2P0HA 3FEHA 4EJNA 1PLSA 1P6SA 1W1HA 1NTYA 5D3VA 1WJMA 1ZSQA 4ZRJA 1DDWA 3WA0A 3D8DA 4CHMA 1XD4A 2ELBA 2W2XD 1QQGA 3NWAA 1TJ6A 1FHOA 3TO1A 2H7DA 3AU5A 1H4RA 1PFJA 1TXDA 3GYOA 3HIEA 2ZKMX 4HAZB 1K5DB 2Q13A 1XR0B 3TCAA 2YVCA 3KY9A 1NI2A 2X18A 5HE1A 1Y19B 2RNRB 2Z0QA 4H8SA 1J0WA 5C6RA 3GYPA 4IFSA 3F5RA 4L6EA 5KCVA 2R2YA 1X86A 3QIJA 3HQCA 5KQ4A 2PZ1A 1I2HA 1LW3A 3TW1A 2EMSA 4HSIA 1BAKA 4GNKB 2YS5A 4GMVA 4HAWB 2LKOA 4KAXB 2Y7BA 1QC6A 2DX1A 2NZ8B 5EFXA 5HE0A 1WVHA 1ZC3B 4EMOA 4F7GA 3UZTA 4NY0A 2ROVA 1XODA 3QBVB 2Z59A 1OQNA 2H7EA 2OTXA 2HE7A 5D3XA 3A8QA 4KHBA 2GJYA 2UZRA 4A6FA 4B6HA 5HE2A 3KRWA 1DBHA 3PP2A 5DHAB 1KI1B 3D8EA 4A6KA 4K2OA 4K81A 4ZRKA 1GC6A 1KZGA 1ZVRA 2L2IA 2JP2A 3AJ4A 2RLOA 4GN1A 2YS3A 3NWDA 1U5EA 2FJUB 2DYQA 1MAIA 5M4YB 2FJLA 4HHVA 2YT0A 2D9YA 2I1KA 2Y8FA 2VSZA 2QKMA 4HDQA 1DROA 1W1GA 1MIZB 3RCPA 4HDOA 3KRXA 1FGYA 4HB3B 4OT1A 4IAPA 3HSAA 4HB0B 1U2BA 2YT1A 3G9WA 3SO6A 5JP4A 1X11A 2Z0PA 2DKPA 2LOXA 1BTNA 2W2WA 4XWXA 4Y94A 5DH9B 1UNPA 2D11A 4Z2NA 3VIAA 5DIFB 2K2JA 4WSFA 2R0DA 4KVGB 2RGNB 2NMBA 1X1FA 4QJ3B 2DHIA 1U5GA 1X1GA 5L81A 3A8PA 5FI0A 2Z4DA 4DX8A 4D0NB 5FI1A 5IRSA 3ZDTA 1WGUA 3ML4A 4QJ4B 4CSQA 3A58A 5J3TA 2J0JA 2KR0A 1SHCA 1ZM0A 1MI1A 1H10A 3D8FA 3OANA 1XCGA 2V76A 2COAA 1ZC4B 4K17A 2Y8GA 2I5FA 1OMWA 2KUQA 4QJ5B 1W1DA 1U29A 1LB1A 3ODOA 4MY6A 2DTCA 2LOZA 4HB2B 2R09A 2DX5A 3TVVA 2IYBA 1I7AA 1V89A 1GC7A 3B77A 3ODXA 4KHAA 1V5UA 2D9XA 4KHBB 2DLWA 3SNHA 2Z14A 4A6FB 3CXBB 2J0MA 1NU2A 4HAUB 5C5BA 4NSWA 2AEHA 4HB4B 2D2QA 3X23A 4TYZA 3ZVRA 1BTKA 2CY5A 4PNKA 4YL8A 1P3RA 2DYNA 1FAOA 1Y5OA 2K49A 2RUKB 3SUZA 4GXBA 1Q67A 3AU4A 3PSCA 4F7HA 2E2XA 1UEFA 1AQCA 4F7UP 3HK0A 3P7ZA 1MK9B 1UPQA 5JHGA 1U27A 1PMSA 1MK7B 2YF0A 3F0WA 4WVFB 1UNQA 2CRFA 3FVCA 2EC1A 2ADZA 2Z0OA 2RVBB 5C16A 4ZRIA 1DDMA 5JHHA 2GUMA 2K8EA 4DXAB 1EGXA 1V5PA 3MPXA 2KIEA 2EMTA 1KZ7A 1TQZA 4PQ0A 3DXCA 4IOYX 2EJ8A 5HE3A 3M1IB 2GS0A 2MFQA 3BJIA 4TKNA 2CY4A 5D27A 2K2UA 2CODA 3BINA 1AWEA 4Z2MB 3DXDA 2LYDA 4MT7A 1UPRA 5J3QA 1ZYIA 2VRWB 1SGHA 2RSGA 3HW2B 4WJ7A 3V5WA 3VOQA 2KGXB 2MDXA 1WG7A 2YT2A 4DBBA 2DA0A 3N7CA 1RRPB 1WI1A 3KZ1A 1V88A 1K5GB 2D9ZA 2J0KA 3PZDA 5CLQB 2W2XC 3QWMA 2D9VA 3DXEA 2P8VA 1N3HA 4K2PA 2D9WA 1E5WA 5I2MA 1GG3A
chains in the Genus database with same CATH topology
2OQBA 3SYXA 4HAVB 2MWNB 5C79A 2YSZA 1U5FA 1XX0A 5GOWB 4C0AA 1DYNA 5C5BB 1J19A 5DHFB 3NSUA 2GCLA 2LULA 2AL6A 5CLLB 1RJ2A 5D3WA 5DI9B 2YRYA 4BBKA 2KCJA 4GPTB 1V5MA 2ROZB 1B55A 2J59M 4HAXB 3TFMA 1EF1A 4MK0A 4DX90 1FOEA 2HTHB 3P6AA 1U5DA 1NTVA 3PVUA 3U8ZA 1WGQA 1WJ1A 4GZUA 1P5TA 2LG1A 1FB8A 4HAYB 4A6HA 2N23A 3FM8C 2P0FA 3MDBC 2UZSA 4HATB 5KQ1A 2P0DA 2GCJA 3LJUX 5D3YA 5J3YA 3ODWA 5LONB 1MPHA 2COCA 1UNRA 2XQNM 3KSYA 2DHJA 3A98B 1FGZA 3O96A 2UVMA 2VKIA 3IVFA 1EAZA 1FHXA 1Z87A 3PVLA 2M38A 4CHJA 2K00A 2D10A 2KUPA 1M7EA 3WYFB 2MKRA 1BWNA 3T06A 3FSSA 2DFKA 1EVHA 1V61A 2QKLA 1M7RA 4GMXB 3PVWA 3ULBA 5LOPB 4YONA 2N0YA 2DN6A 4EKUA 1DDVA 3CIKA 3ULCA 2YS1A 3PG7A 1X05A 1IRSA 2BCJA 2ZPYA 2L1CA 2CAYA 2G35A 1ISNA 4P7IA 1FHWA 2D4QA 2M14A 4CYEA 1MKEA 2ELAA 5JLJB 4A5KA 1MIXA 2I5CA 4KHOA 3SV1A 2I1JA 2DKQA 3PEGA 2COFA 1OY2A 2IFSA 2DHKA 1XKEA 3U7DA 2P0HA 3FEHA 4EJNA 1PLSA 1P6SA 1W1HA 1NTYA 5D3VA 1WJMA 1ZSQA 4ZRJA 1DDWA 3WA0A 3D8DA 4CHMA 1XD4A 2ELBA 2W2XD 1QQGA 1TJ6A 1FHOA 3TO1A 2H7DA 3AU5A 1H4RA 1PFJA 1TXDA 3GYOA 4HAZB 1K5DB 2Q13A 1XR0B 3TCAA 2YVCA 3KY9A 1NI2A 2X18A 5HE1A 1Y19B 2RNRB 2Z0QA 4H8SA 1J0WA 5C6RA 3GYPA 4IFSA 3F5RA 4L6EA 5KCVA 1X86A 3QIJA 3HQCA 5KQ4A 2PZ1A 1I2HA 1LW3A 3TW1A 2EMSA 1BAKA 2YS5A 4GMVA 4HAWB 2LKOA 4KAXB 2Y7BA 1QC6A 2DX1A 2NZ8B 5EFXA 5HE0A 1WVHA 1ZC3B 4EMOA 4F7GA 3UZTA 4NY0A 2ROVA 1XODA 3QBVB 1OQNA 2H7EA 2OTXA 2HE7A 5D3XA 3A8QA 2GJYA 2UZRA 4A6FA 4B6HA 5HE2A 3KRWA 1DBHA 3PP2A 5DHAB 1KI1B 3D8EA 4A6KA 4K2OA 4K81A 4ZRKA 1GC6A 1KZGA 1ZVRA 2L2IA 2JP2A 3AJ4A 2RLOA 4GN1A 2YS3A 1U5EA 2DYQA 1MAIA 2FJLA 4HHVA 2YT0A 2D9YA 2I1KA 2Y8FA 2VSZA 2QKMA 4HDQA 1DROA 1W1GA 1MIZB 3RCPA 4HDOA 3KRXA 1FGYA 4HB3B 4IAPA 4HB0B 1U2BA 2YT1A 3G9WA 3SO6A 5JP4A 1X11A 2Z0PA 2DKPA 2LOXA 1BTNA 2W2WA 4XWXA 4Y94A 5DH9B 1UNPA 2D11A 4Z2NA 3VIAA 5DIFB 2K2JA 4WSFA 2R0DA 4KVGB 2RGNB 2NMBA 1X1FA 2DHIA 1U5GA 1X1GA 5L81A 3A8PA 5FI0A 4DX8A 4D0NB 5FI1A 3ZDTA 1WGUA 3ML4A 5J3TA 2J0JA 1SHCA 1ZM0A 1H10A 3D8FA 3OANA 1XCGA 2V76A 2COAA 1ZC4B 4K17A 2Y8GA 2I5FA 1OMWA 1W1DA 1U29A 1LB1A 3ODOA 4MY6A 2DTCA 2LOZA 4HB2B 2R09A 2DX5A 3TVVA 2IYBA 1I7AA 1V89A 1GC7A 3ODXA 4KHAA 1V5UA 2D9XA 4KHBB 2DLWA 3SNHA 4A6FB 3CXBB 2J0MA 1NU2A 4HAUB 5C5BA 4NSWA 2AEHA 4HB4B 2D2QA 3X23A 4TYZA 3ZVRA 1BTKA 2CY5A 4PNKA 4YL8A 1P3RA 2DYNA 1FAOA 1Y5OA 2RUKB 3SUZA 4GXBA 1Q67A 3AU4A 3PSCA 4F7HA 2E2XA 1UEFA 1AQCA 4F7UP 3HK0A 3P7ZA 1MK9B 1UPQA 5JHGA 1U27A 1PMSA 1MK7B 2YF0A 3F0WA 4WVFB 1UNQA 2CRFA 2EC1A 2ADZA 2Z0OA 2RVBB 5C16A 4ZRIA 1DDMA 5JHHA 4DXAB 1EGXA 1V5PA 3MPXA 2EMTA 1KZ7A 1TQZA 4PQ0A 3DXCA 4IOYX 2EJ8A 5HE3A 3M1IB 2GS0A 2MFQA 3BJIA 4TKNA 2CY4A 5D27A 2K2UA 2CODA 3BINA 1AWEA 4Z2MB 3DXDA 2LYDA 4MT7A 1UPRA 5J3QA 2VRWB 1SGHA 2RSGA 3HW2B 4WJ7A 3V5WA 3VOQA 2KGXB 2MDXA 1WG7A 4DBBA 2DA0A 3N7CA 1RRPB 1WI1A 3KZ1A 1V88A 1K5GB 2D9ZA 2J0KA 3PZDA 5CLQB 2W2XC 3QWMA 2D9VA 3DXEA 2P8VA 1N3HA 4K2PA 2D9WA 1E5WA 1GG3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OQB A;  3SYX A;  4HAV B;  2MWN B;  5C79 A;  2YSZ A;  1U5F A;  1XX0 A;  5GOW B;  4C0A A;  1DYN A;  5C5B B;  1J19 A;  5DHF B;  3NSU A;  2GCL A;  2LUL A;  2AL6 A;  5CLL B;  1RJ2 A;  5D3W A;  5DI9 B;  2YRY A;  4BBK A;  2KCJ A;  4GPT B;  1V5M A;  2ROZ B;  1B55 A;  2J59 M;  4HAX B;  3TFM A;  1EF1 A;  4MK0 A;  4DX9 0;  1FOE A;  2HTH B;  3P6A A;  1U5D A;  1NTV A;  3PVU A;  3U8Z A;  1WGQ A;  1WJ1 A;  4GZU A;  1P5T A;  2LG1 A;  1FB8 A;  4HAY B;  4A6H A;  2N23 A;  3FM8 C;  2P0F A;  3MDB C;  2UZS A;  4HAT B;  5KQ1 A;  2P0D A;  2GCJ A;  3LJU X;  5D3Y A;  5J3Y A;  3ODW A;  5LON B;  1MPH A;  2COC A;  1UNR A;  2XQN M;  3KSY A;  2DHJ A;  3A98 B;  1FGZ A;  3O96 A;  2UVM A;  2VKI A;  3IVF A;  1EAZ A;  1FHX A;  1Z87 A;  3PVL A;  2M38 A;  4CHJ A;  2K00 A;  2D10 A;  2KUP A;  1M7E A;  3WYF B;  2MKR A;  1BWN A;  3T06 A;  3FSS A;  2DFK A;  1EVH A;  1V61 A;  2QKL A;  1M7R A;  4GMX B;  3PVW A;  3ULB A;  5LOP B;  4YON A;  2N0Y A;  2DN6 A;  4EKU A;  1DDV A;  3CIK A;  3ULC A;  2YS1 A;  3PG7 A;  1X05 A;  1IRS A;  2BCJ A;  2ZPY A;  2L1C A;  2CAY A;  2G35 A;  1ISN A;  4P7I A;  1FHW A;  2D4Q A;  2M14 A;  4CYE A;  1MKE A;  2ELA A;  5JLJ B;  4A5K A;  1MIX A;  2I5C A;  4KHO A;  3SV1 A;  2I1J A;  2DKQ A;  3PEG A;  2COF A;  1OY2 A;  2IFS A;  2DHK A;  1XKE A;  3U7D A;  2P0H A;  3FEH A;  4EJN A;  1PLS A;  1P6S A;  1W1H A;  1NTY A;  5D3V A;  1WJM A;  1ZSQ A;  4ZRJ A;  1DDW A;  3WA0 A;  3D8D A;  4CHM A;  1XD4 A;  2ELB A;  2W2X D;  1QQG A;  1TJ6 A;  1FHO A;  3TO1 A;  2H7D A;  3AU5 A;  1H4R A;  1PFJ A;  1TXD A;  3GYO A;  4HAZ B;  1K5D B;  2Q13 A;  1XR0 B;  3TCA A;  2YVC A;  3KY9 A;  1NI2 A;  2X18 A;  5HE1 A;  1Y19 B;  2RNR B;  2Z0Q A;  4H8S A;  1J0W A;  5C6R A;  3GYP A;  4IFS A;  3F5R A;  4L6E A;  5KCV A;  1X86 A;  3QIJ A;  3HQC A;  5KQ4 A;  2PZ1 A;  1I2H A;  1LW3 A;  3TW1 A;  2EMS A;  1BAK A;  2YS5 A;  4GMV A;  4HAW B;  2LKO A;  4KAX B;  2Y7B A;  1QC6 A;  2DX1 A;  2NZ8 B;  5EFX A;  5HE0 A;  1WVH A;  1ZC3 B;  4EMO A;  4F7G A;  3UZT A;  4NY0 A;  2ROV A;  1XOD A;  3QBV B;  1OQN A;  2H7E A;  2OTX A;  2HE7 A;  5D3X A;  3A8Q A;  2GJY A;  2UZR A;  4A6F A;  4B6H A;  5HE2 A;  3KRW A;  1DBH A;  3PP2 A;  5DHA B;  1KI1 B;  3D8E A;  4A6K A;  4K2O A;  4K81 A;  4ZRK A;  1GC6 A;  1KZG A;  1ZVR A;  2L2I A;  2JP2 A;  3AJ4 A;  2RLO A;  4GN1 A;  2YS3 A;  1U5E A;  2DYQ A;  1MAI A;  2FJL A;  4HHV A;  2YT0 A;  2D9Y A;  2I1K A;  2Y8F A;  2VSZ A;  2QKM A;  4HDQ A;  1DRO A;  1W1G A;  1MIZ B;  3RCP A;  4HDO A;  3KRX A;  1FGY A;  4HB3 B;  4IAP A;  4HB0 B;  1U2B A;  2YT1 A;  3G9W A;  3SO6 A;  5JP4 A;  1X11 A;  2Z0P A;  2DKP A;  2LOX A;  1BTN A;  2W2W A;  4XWX A;  4Y94 A;  5DH9 B;  1UNP A;  2D11 A;  4Z2N A;  3VIA A;  5DIF B;  2K2J A;  4WSF A;  2R0D A;  4KVG B;  2RGN B;  2NMB A;  1X1F A;  2DHI A;  1U5G A;  1X1G A;  5L81 A;  3A8P A;  5FI0 A;  4DX8 A;  4D0N B;  5FI1 A;  3ZDT A;  1WGU A;  3ML4 A;  5J3T A;  2J0J A;  1SHC A;  1ZM0 A;  1H10 A;  3D8F A;  3OAN A;  1XCG A;  2V76 A;  2COA A;  1ZC4 B;  4K17 A;  2Y8G A;  2I5F A;  1OMW A;  1W1D A;  1U29 A;  1LB1 A;  3ODO A;  4MY6 A;  2DTC A;  2LOZ A;  4HB2 B;  2R09 A;  2DX5 A;  3TVV A;  2IYB A;  1I7A A;  1V89 A;  1GC7 A;  3ODX A;  4KHA A;  1V5U A;  2D9X A;  4KHB B;  2DLW A;  3SNH A;  4A6F B;  3CXB B;  2J0M A;  1NU2 A;  4HAU B;  5C5B A;  4NSW A;  2AEH A;  4HB4 B;  2D2Q A;  3X23 A;  4TYZ A;  3ZVR A;  1BTK A;  2CY5 A;  4PNK A;  4YL8 A;  1P3R A;  2DYN A;  1FAO A;  1Y5O A;  2RUK B;  3SUZ A;  4GXB A;  1Q67 A;  3AU4 A;  3PSC A;  4F7H A;  2E2X A;  1UEF A;  1AQC A;  4F7U P;  3HK0 A;  3P7Z A;  1MK9 B;  1UPQ A;  5JHG A;  1U27 A;  1PMS A;  1MK7 B;  2YF0 A;  3F0W A;  4WVF B;  1UNQ A;  2CRF A;  2EC1 A;  2ADZ A;  2Z0O A;  2RVB B;  5C16 A;  4ZRI A;  1DDM A;  5JHH A;  4DXA B;  1EGX A;  1V5P A;  3MPX A;  2EMT A;  1KZ7 A;  1TQZ A;  4PQ0 A;  3DXC A;  4IOY X;  2EJ8 A;  5HE3 A;  3M1I B;  2GS0 A;  2MFQ A;  3BJI A;  4TKN A;  2CY4 A;  5D27 A;  2K2U A;  2COD A;  3BIN A;  1AWE A;  4Z2M B;  3DXD A;  2LYD A;  4MT7 A;  1UPR A;  5J3Q A;  2VRW B;  1SGH A;  2RSG A;  3HW2 B;  4WJ7 A;  3V5W A;  3VOQ A;  2KGX B;  2MDX A;  1WG7 A;  4DBB A;  2DA0 A;  3N7C A;  1RRP B;  1WI1 A;  3KZ1 A;  1V88 A;  1K5G B;  2D9Z A;  2J0K A;  3PZD A;  5CLQ B;  2W2X C;  3QWM A;  2D9V A;  3DXE A;  2P8V A;  1N3H A;  4K2P A;  2D9W A;  1E5W A;  1GG3 A; 
#chains in the Genus database with same CATH topology
 2OQB A;  3SYX A;  4HAV B;  2MWN B;  5C79 A;  2YSZ A;  1U5F A;  1XX0 A;  5GOW B;  4C0A A;  1DYN A;  1T77 A;  5C5B B;  1J19 A;  5DHF B;  3NSU A;  2GCL A;  2NBV A;  2LUL A;  2AL6 A;  5CLL B;  1RJ2 A;  5D3W A;  5DI9 B;  2YRY A;  4BBK A;  2KCJ A;  4GPT B;  1V5M A;  2ROZ B;  1B55 A;  3NW8 A;  2J59 M;  4HAX B;  3TFM A;  1EF1 A;  4OSN A;  4MK0 A;  4DX9 0;  1FOE A;  3OHM B;  2HTH B;  3P6A A;  1U5D A;  1NTV A;  3PVU A;  3U8Z A;  1WGQ A;  4GOU A;  1WJ1 A;  4GZU A;  1P5T A;  4DIX A;  2KIG A;  2LG1 A;  1FB8 A;  4HAY B;  4A6H A;  2N23 A;  3FM8 C;  2P0F A;  3MDB C;  2UZS A;  4HAT B;  5KQ1 A;  2P0D A;  2GCJ A;  3LJU X;  5D3Y A;  5J3Y A;  3ODW A;  5LON B;  1MPH A;  2COC A;  1UNR A;  3U12 A;  2XQN M;  3KSY A;  2DHJ A;  3A98 B;  1FGZ A;  3O96 A;  5I2S A;  2UVM A;  2VKI A;  3IVF A;  1EAZ A;  1FHX A;  1Z87 A;  3PVL A;  2M38 A;  4CHJ A;  2K00 A;  2RRF A;  5LG4 B;  2D10 A;  2KUP A;  1M7E A;  3WYF B;  2MKR A;  1BWN A;  3T06 A;  3FSS A;  2DFK A;  1EVH A;  1V61 A;  2QKL A;  1M7R A;  4GMX B;  3PVW A;  3ULB A;  5LOP B;  4YON A;  2N0Y A;  4QXA B;  2DN6 A;  4EKU A;  1DDV A;  3CIK A;  4D6W A;  3ULC A;  2YS1 A;  3PG7 A;  1X05 A;  1IRS A;  2BCJ A;  2ZPY A;  2L1C A;  2CAY A;  2G35 A;  4L1R A;  1ISN A;  4P7I A;  1FHW A;  2D4Q A;  2M14 A;  3DCX A;  4CYE A;  1MKE A;  2ELA A;  5JLJ B;  4A5K A;  1MIX A;  2I5C A;  2Z13 A;  4KHO A;  3SV1 A;  2I1J A;  2DKQ A;  3PEG A;  2COF A;  1OY2 A;  3NWF A;  2IFS A;  2DHK A;  1XKE A;  3U7D A;  2P0H A;  3FEH A;  4EJN A;  1PLS A;  1P6S A;  1W1H A;  1NTY A;  5D3V A;  1WJM A;  1ZSQ A;  4ZRJ A;  1DDW A;  3WA0 A;  3D8D A;  4CHM A;  1XD4 A;  2ELB A;  2W2X D;  1QQG A;  3NWA A;  1TJ6 A;  1FHO A;  3TO1 A;  2H7D A;  3AU5 A;  1H4R A;  1PFJ A;  1TXD A;  3GYO A;  3HIE A;  2ZKM X;  4HAZ B;  1K5D B;  2Q13 A;  1XR0 B;  3TCA A;  2YVC A;  3KY9 A;  1NI2 A;  2X18 A;  5HE1 A;  1Y19 B;  2RNR B;  2Z0Q A;  4H8S A;  1J0W A;  5C6R A;  3GYP A;  4IFS A;  3F5R A;  4L6E A;  5KCV A;  2R2Y A;  1X86 A;  3QIJ A;  3HQC A;  5KQ4 A;  2PZ1 A;  1I2H A;  1LW3 A;  3TW1 A;  2EMS A;  4HSI A;  1BAK A;  4GNK B;  2YS5 A;  4GMV A;  4HAW B;  2LKO A;  4KAX B;  2Y7B A;  1QC6 A;  2DX1 A;  2NZ8 B;  5EFX A;  5HE0 A;  1WVH A;  1ZC3 B;  4EMO A;  4F7G A;  3UZT A;  4NY0 A;  2ROV A;  1XOD A;  3QBV B;  2Z59 A;  1OQN A;  2H7E A;  2OTX A;  2HE7 A;  5D3X A;  3A8Q A;  4KHB A;  2GJY A;  2UZR A;  4A6F A;  4B6H A;  5HE2 A;  3KRW A;  1DBH A;  3PP2 A;  5DHA B;  1KI1 B;  3D8E A;  4A6K A;  4K2O A;  4K81 A;  4ZRK A;  1GC6 A;  1KZG A;  1ZVR A;  2L2I A;  2JP2 A;  3AJ4 A;  2RLO A;  4GN1 A;  2YS3 A;  3NWD A;  1U5E A;  2FJU B;  2DYQ A;  1MAI A;  5M4Y B;  2FJL A;  4HHV A;  2YT0 A;  2D9Y A;  2I1K A;  2Y8F A;  2VSZ A;  2QKM A;  4HDQ A;  1DRO A;  1W1G A;  1MIZ B;  3RCP A;  4HDO A;  3KRX A;  1FGY A;  4HB3 B;  4OT1 A;  4IAP A;  3HSA A;  4HB0 B;  1U2B A;  2YT1 A;  3G9W A;  3SO6 A;  5JP4 A;  1X11 A;  2Z0P A;  2DKP A;  2LOX A;  1BTN A;  2W2W A;  4XWX A;  4Y94 A;  5DH9 B;  1UNP A;  2D11 A;  4Z2N A;  3VIA A;  5DIF B;  2K2J A;  4WSF A;  2R0D A;  4KVG B;  2RGN B;  2NMB A;  1X1F A;  4QJ3 B;  2DHI A;  1U5G A;  1X1G A;  5L81 A;  3A8P A;  5FI0 A;  2Z4D A;  4DX8 A;  4D0N B;  5FI1 A;  5IRS A;  3ZDT A;  1WGU A;  3ML4 A;  4QJ4 B;  4CSQ A;  3A58 A;  5J3T A;  2J0J A;  2KR0 A;  1SHC A;  1ZM0 A;  1MI1 A;  1H10 A;  3D8F A;  3OAN A;  1XCG A;  2V76 A;  2COA A;  1ZC4 B;  4K17 A;  2Y8G A;  2I5F A;  1OMW A;  2KUQ A;  4QJ5 B;  1W1D A;  1U29 A;  1LB1 A;  3ODO A;  4MY6 A;  2DTC A;  2LOZ A;  4HB2 B;  2R09 A;  2DX5 A;  3TVV A;  2IYB A;  1I7A A;  1V89 A;  1GC7 A;  3B77 A;  3ODX A;  4KHA A;  1V5U A;  2D9X A;  4KHB B;  2DLW A;  3SNH A;  2Z14 A;  4A6F B;  3CXB B;  2J0M A;  1NU2 A;  4HAU B;  5C5B A;  4NSW A;  2AEH A;  4HB4 B;  2D2Q A;  3X23 A;  4TYZ A;  3ZVR A;  1BTK A;  2CY5 A;  4PNK A;  4YL8 A;  1P3R A;  2DYN A;  1FAO A;  1Y5O A;  2K49 A;  2RUK B;  3SUZ A;  4GXB A;  1Q67 A;  3AU4 A;  3PSC A;  4F7H A;  2E2X A;  1UEF A;  1AQC A;  4F7U P;  3HK0 A;  3P7Z A;  1MK9 B;  1UPQ A;  5JHG A;  1U27 A;  1PMS A;  1MK7 B;  2YF0 A;  3F0W A;  4WVF B;  1UNQ A;  2CRF A;  3FVC A;  2EC1 A;  2ADZ A;  2Z0O A;  2RVB B;  5C16 A;  4ZRI A;  1DDM A;  5JHH A;  2GUM A;  2K8E A;  4DXA B;  1EGX A;  1V5P A;  3MPX A;  2KIE A;  2EMT A;  1KZ7 A;  1TQZ A;  4PQ0 A;  3DXC A;  4IOY X;  2EJ8 A;  5HE3 A;  3M1I B;  2GS0 A;  2MFQ A;  3BJI A;  4TKN A;  2CY4 A;  5D27 A;  2K2U A;  2COD A;  3BIN A;  1AWE A;  4Z2M B;  3DXD A;  2LYD A;  4MT7 A;  1UPR A;  5J3Q A;  1ZYI A;  2VRW B;  1SGH A;  2RSG A;  3HW2 B;  4WJ7 A;  3V5W A;  3VOQ A;  2KGX B;  2MDX A;  1WG7 A;  2YT2 A;  4DBB A;  2DA0 A;  3N7C A;  1RRP B;  1WI1 A;  3KZ1 A;  1V88 A;  1K5G B;  2D9Z A;  2J0K A;  3PZD A;  5CLQ B;  2W2X C;  3QWM A;  2D9V A;  3DXE A;  2P8V A;  1N3H A;  4K2P A;  2D9W A;  1E5W A;  5I2M A;  1GG3 A; 
#chains in the Genus database with same CATH homology
 2OQB A;  3SYX A;  4HAV B;  2MWN B;  5C79 A;  2YSZ A;  1U5F A;  1XX0 A;  5GOW B;  4C0A A;  1DYN A;  5C5B B;  1J19 A;  5DHF B;  3NSU A;  2GCL A;  2LUL A;  2AL6 A;  5CLL B;  1RJ2 A;  5D3W A;  5DI9 B;  2YRY A;  4BBK A;  2KCJ A;  4GPT B;  1V5M A;  2ROZ B;  1B55 A;  2J59 M;  4HAX B;  3TFM A;  1EF1 A;  4MK0 A;  4DX9 0;  1FOE A;  2HTH B;  3P6A A;  1U5D A;  1NTV A;  3PVU A;  3U8Z A;  1WGQ A;  1WJ1 A;  4GZU A;  1P5T A;  2LG1 A;  1FB8 A;  4HAY B;  4A6H A;  2N23 A;  3FM8 C;  2P0F A;  3MDB C;  2UZS A;  4HAT B;  5KQ1 A;  2P0D A;  2GCJ A;  3LJU X;  5D3Y A;  5J3Y A;  3ODW A;  5LON B;  1MPH A;  2COC A;  1UNR A;  2XQN M;  3KSY A;  2DHJ A;  3A98 B;  1FGZ A;  3O96 A;  2UVM A;  2VKI A;  3IVF A;  1EAZ A;  1FHX A;  1Z87 A;  3PVL A;  2M38 A;  4CHJ A;  2K00 A;  2D10 A;  2KUP A;  1M7E A;  3WYF B;  2MKR A;  1BWN A;  3T06 A;  3FSS A;  2DFK A;  1EVH A;  1V61 A;  2QKL A;  1M7R A;  4GMX B;  3PVW A;  3ULB A;  5LOP B;  4YON A;  2N0Y A;  2DN6 A;  4EKU A;  1DDV A;  3CIK A;  3ULC A;  2YS1 A;  3PG7 A;  1X05 A;  1IRS A;  2BCJ A;  2ZPY A;  2L1C A;  2CAY A;  2G35 A;  1ISN A;  4P7I A;  1FHW A;  2D4Q A;  2M14 A;  4CYE A;  1MKE A;  2ELA A;  5JLJ B;  4A5K A;  1MIX A;  2I5C A;  4KHO A;  3SV1 A;  2I1J A;  2DKQ A;  3PEG A;  2COF A;  1OY2 A;  2IFS A;  2DHK A;  1XKE A;  3U7D A;  2P0H A;  3FEH A;  4EJN A;  1PLS A;  1P6S A;  1W1H A;  1NTY A;  5D3V A;  1WJM A;  1ZSQ A;  4ZRJ A;  1DDW A;  3WA0 A;  3D8D A;  4CHM A;  1XD4 A;  2ELB A;  2W2X D;  1QQG A;  1TJ6 A;  1FHO A;  3TO1 A;  2H7D A;  3AU5 A;  1H4R A;  1PFJ A;  1TXD A;  3GYO A;  4HAZ B;  1K5D B;  2Q13 A;  1XR0 B;  3TCA A;  2YVC A;  3KY9 A;  1NI2 A;  2X18 A;  5HE1 A;  1Y19 B;  2RNR B;  2Z0Q A;  4H8S A;  1J0W A;  5C6R A;  3GYP A;  4IFS A;  3F5R A;  4L6E A;  5KCV A;  1X86 A;  3QIJ A;  3HQC A;  5KQ4 A;  2PZ1 A;  1I2H A;  1LW3 A;  3TW1 A;  2EMS A;  1BAK A;  2YS5 A;  4GMV A;  4HAW B;  2LKO A;  4KAX B;  2Y7B A;  1QC6 A;  2DX1 A;  2NZ8 B;  5EFX A;  5HE0 A;  1WVH A;  1ZC3 B;  4EMO A;  4F7G A;  3UZT A;  4NY0 A;  2ROV A;  1XOD A;  3QBV B;  1OQN A;  2H7E A;  2OTX A;  2HE7 A;  5D3X A;  3A8Q A;  2GJY A;  2UZR A;  4A6F A;  4B6H A;  5HE2 A;  3KRW A;  1DBH A;  3PP2 A;  5DHA B;  1KI1 B;  3D8E A;  4A6K A;  4K2O A;  4K81 A;  4ZRK A;  1GC6 A;  1KZG A;  1ZVR A;  2L2I A;  2JP2 A;  3AJ4 A;  2RLO A;  4GN1 A;  2YS3 A;  1U5E A;  2DYQ A;  1MAI A;  2FJL A;  4HHV A;  2YT0 A;  2D9Y A;  2I1K A;  2Y8F A;  2VSZ A;  2QKM A;  4HDQ A;  1DRO A;  1W1G A;  1MIZ B;  3RCP A;  4HDO A;  3KRX A;  1FGY A;  4HB3 B;  4IAP A;  4HB0 B;  1U2B A;  2YT1 A;  3G9W A;  3SO6 A;  5JP4 A;  1X11 A;  2Z0P A;  2DKP A;  2LOX A;  1BTN A;  2W2W A;  4XWX A;  4Y94 A;  5DH9 B;  1UNP A;  2D11 A;  4Z2N A;  3VIA A;  5DIF B;  2K2J A;  4WSF A;  2R0D A;  4KVG B;  2RGN B;  2NMB A;  1X1F A;  2DHI A;  1U5G A;  1X1G A;  5L81 A;  3A8P A;  5FI0 A;  4DX8 A;  4D0N B;  5FI1 A;  3ZDT A;  1WGU A;  3ML4 A;  5J3T A;  2J0J A;  1SHC A;  1ZM0 A;  1H10 A;  3D8F A;  3OAN A;  1XCG A;  2V76 A;  2COA A;  1ZC4 B;  4K17 A;  2Y8G A;  2I5F A;  1OMW A;  1W1D A;  1U29 A;  1LB1 A;  3ODO A;  4MY6 A;  2DTC A;  2LOZ A;  4HB2 B;  2R09 A;  2DX5 A;  3TVV A;  2IYB A;  1I7A A;  1V89 A;  1GC7 A;  3ODX A;  4KHA A;  1V5U A;  2D9X A;  4KHB B;  2DLW A;  3SNH A;  4A6F B;  3CXB B;  2J0M A;  1NU2 A;  4HAU B;  5C5B A;  4NSW A;  2AEH A;  4HB4 B;  2D2Q A;  3X23 A;  4TYZ A;  3ZVR A;  1BTK A;  2CY5 A;  4PNK A;  4YL8 A;  1P3R A;  2DYN A;  1FAO A;  1Y5O A;  2RUK B;  3SUZ A;  4GXB A;  1Q67 A;  3AU4 A;  3PSC A;  4F7H A;  2E2X A;  1UEF A;  1AQC A;  4F7U P;  3HK0 A;  3P7Z A;  1MK9 B;  1UPQ A;  5JHG A;  1U27 A;  1PMS A;  1MK7 B;  2YF0 A;  3F0W A;  4WVF B;  1UNQ A;  2CRF A;  2EC1 A;  2ADZ A;  2Z0O A;  2RVB B;  5C16 A;  4ZRI A;  1DDM A;  5JHH A;  4DXA B;  1EGX A;  1V5P A;  3MPX A;  2EMT A;  1KZ7 A;  1TQZ A;  4PQ0 A;  3DXC A;  4IOY X;  2EJ8 A;  5HE3 A;  3M1I B;  2GS0 A;  2MFQ A;  3BJI A;  4TKN A;  2CY4 A;  5D27 A;  2K2U A;  2COD A;  3BIN A;  1AWE A;  4Z2M B;  3DXD A;  2LYD A;  4MT7 A;  1UPR A;  5J3Q A;  2VRW B;  1SGH A;  2RSG A;  3HW2 B;  4WJ7 A;  3V5W A;  3VOQ A;  2KGX B;  2MDX A;  1WG7 A;  4DBB A;  2DA0 A;  3N7C A;  1RRP B;  1WI1 A;  3KZ1 A;  1V88 A;  1K5G B;  2D9Z A;  2J0K A;  3PZD A;  5CLQ B;  2W2X C;  3QWM A;  2D9V A;  3DXE A;  2P8V A;  1N3H A;  4K2P A;  2D9W A;  1E5W A;  1GG3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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