1UNQA

High resolution crystal structure of the pleckstrin homology domain of protein kinase b/akt bound to ins(1,3,4,5)-tetrakisphophate
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
117
structure length
117
Chain Sequence
SMSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords RAC-ALPHA SERINE/THREONINE KINASE
publication title Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change.
pubmed doi rcsb
source organism Homo sapiens
total genus 32
structure length 117
sequence length 117
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2003-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1unqA00
2DX5A 1ZC3B 1E5WA 1Q67A 3N7CA 3NSUA 1EVHA 3TCAA 5J3QA 2Z0PA 4GMVA 2ADZA 2DYNA 3P6AA 3QBVB 4D0NB 4K2PA 2ELBA 4A6HA 2J0MA 2IYBA 3BINA 4MY6A 3QIJA 5FI0A 2PZ1A 2DHIA 4KVGB 2VSZA 3M1IB 1DBHA 2UVMA 1WGQA 1U27A 2YS1A 5FI1A 4K81A 4BBKA 2ZPYA 5D3VA 2R0DA 2CAYA 4ZRKA 1XX0A 2QKLA 2DYQA 3V5WA 1DYNA 2P0FA 1H10A 3D8EA 1UEFA 1BTNA 1ZC4B 2D9XA 2H7EA 2I5FA 1M7EA 2KUPA 1BAKA 2RLOA 1V88A 5DI9B 2EMSA 2YS5A 5CLQB 1FHXA 5C6RA 1B55A 4PNKA 2P0HA 1EGXA 1NTYA 2G35A 2DN6A 2L1CA 2RGNB 4WVFB 4EMOA 4HAUB 4F7GA 1PFJA 1UNRA 4P7IA 5D3XA 1W1GA 5J3YA 3T06A 4MT7A 2D2QA 1U5GA 1DDVA 4F7UP 4DXAB 3DXCA 1BWNA 1SHCA 2K00A 3A8QA 2YF0A 1KI1B 1FAOA 3IVFA 1Z87A 3A98B 4F7HA 2XQNM 2MDXA 2Z0OA 1U5DA 4HDQA 3KSYA 1MAIA 3PSCA 2I1JA 1ZM0A 2CRFA 1WG7A 2COFA 3PG7A 1OMWA 3SUZA 1XR0B 2YRYA 3FSSA 1WGUA 1LW3A 1V5PA 5HE2A 2P0DA 2AEHA 2EJ8A 2LOZA 1LB1A 1ZVRA 4YONA 5C16A 3FM8C 4WJ7A 2VKIA 2D4QA 2N23A 4DX8A 2GCLA 1GC6A 2DA0A 2YSZA 2DKPA 4A5KA 1FHOA 5DHFB 1IRSA 4A6FA 2ELAA 4CHMA 1MIZB 5C5BB 5JHHA 4A6KA 1WVHA 3BJIA 5KQ1A 3AU5A 2OTXA 2J0JA 2COAA 2DLWA 2ROVA 3ZVRA 3TW1A 2JP2A 2D9ZA 2DFKA 1XD4A 4HAWB 2H7DA 4HB0B 4TYZA 1WJ1A 2LKOA 2KGXB 2D10A 4IFSA 4TKNA 3A8PA 2M38A 1H4RA 1PMSA 3DXEA 4C0AA 2QKMA 5KQ4A 1Y19B 4DBBA 3X23A 1I7AA 4DX90 5JLJB 1AWEA 1WI1A 1V5MA 1FGZA 2DTCA 3HK0A 1M7RA 3KY9A 4IAPA 4Z2MB 2VRWB 2YT0A 4GN1A 4HAXB 1ISNA 2W2XC 4EKUA 1MKEA 3FEHA 2L2IA 2N0YA 5LOPB 2MKRA 1EAZA 3P7ZA 2R09A 3VIAA 1FHWA 1NU2A 1XODA 3GYPA 1RJ2A 4Y94A 5CLLB 4YL8A 2D9WA 2DHKA 2RVBB 2YT1A 3UZTA 1FOEA 3HW2B 4WSFA 4PQ0A 4K17A 1TJ6A 5J3TA 2UZRA 2EC1A 3QWMA 3U8ZA 3OANA 2UZSA 2LULA 4EJNA 3DXDA 1XCGA 1DROA 1TQZA 2GCJA 3PVUA 2K2UA 3WA0A 4KHBB 2J0KA 2I5CA 2YVCA 3ODOA 1UPQA 2Y8GA 1QC6A 1OQNA 3PVLA 3SO6A 1W1DA 4NSWA 3F5RA 5JP4A 4HATB 4KHAA 2Q13A 3ODWA 1U2BA 5JHGA 3TO1A 4Z2NA 4HB2B 1UPRA 2I1KA 1RRPB 3ULCA 4HAVB 1P5TA 3LJUX 5HE3A 5D27A 1GG3A 2V76A 1MK9B 2D9VA 3MPXA 1OY2A 2GS0A 1NI2A 4HAYB 1MIXA 1P3RA 1J19A 1U5EA 2RSGA 4HB3B 1J0WA 4ZRIA 3TFMA 1U29A 1V89A 2M14A 2RUKB 3CIKA 2D9YA 4CYEA 3SV1A 2CODA 1QQGA 4GPTB 1N3HA 3G9WA 3CXBB 1MK7B 3KZ1A 2LYDA 4HHVA 2D11A 1K5GB 2W2XD 1I2HA 2DKQA 2RNRB 1U5FA 1DDWA 2KCJA 4IOYX 2YS3A 1Y5OA 2NMBA 4GMXB 1SGHA 2P8VA 1BTKA 3ULBA 4HDOA 2BCJA 2GJYA 2K2JA 4MK0A 2COCA 1WJMA 2LG1A 2Z0QA 1X1FA 3KRXA 3O96A 3KRWA 2DHJA 3D8FA 1X05A 1EF1A 2MWNB 1GC7A 2DX1A 2ROZB 1KZ7A 2Y8FA 3TVVA 2HE7A 5D3WA 2MFQA 4L6EA 1AQCA 1PLSA 3GYOA 5DHAB 2CY4A 3PVWA 4A6FB 2E2XA 3ML4A 4NY0A 5EFXA 2IFSA 3HQCA 1X11A 1KZGA 4B6HA 5C79A 2CY5A 1P6SA 2FJLA 3ODXA 5DH9B 2J59M 4CHJA 3AJ4A 3RCPA 1X86A 3PP2A 1MPHA 2HTHB 3MDBC 3ZDTA 5KCVA 1UNQA 4H8SA 1V5UA 2OQBA 2NZ8B 2LOXA 4K2OA 3AU4A 4HAZB 4GZUA 5HE0A 4GXBA 1DDMA 5D3YA 3SNHA 2X18A 2EMTA 1W1HA 1K5DB 5LONB 3VOQA 5C5BA 1UNPA 4KAXB 1XKEA 3PZDA 3D8DA 3F0WA 5DIFB 4KHOA 2W2WA 1FGYA 4HB4B 4XWXA 2Y7BA 5L81A 1X1GA 1FB8A 1NTVA 5HE1A 3PEGA 3SYXA 3U7DA 1TXDA 2AL6A 5GOWB 1ZSQA 4ZRJA 1V61A 3WYFB
chains in the Genus database with same CATH superfamily
2DX5A 1ZC3B 1E5WA 1Q67A 3N7CA 3NSUA 1EVHA 3TCAA 5J3QA 2Z0PA 3HSAA 4GMVA 2ADZA 2DYNA 3P6AA 3QBVB 4D0NB 4K2PA 3OHMB 2ELBA 4A6HA 2J0MA 2IYBA 3BINA 4MY6A 3QIJA 5FI0A 2PZ1A 2DHIA 4KVGB 2VSZA 3M1IB 1DBHA 2ZKMX 2UVMA 1WGQA 1U27A 4OSNA 2YS1A 5FI1A 4K81A 4BBKA 2ZPYA 5D3VA 2KIEA 2R0DA 2K8EA 5LG4B 2CAYA 4ZRKA 1XX0A 2FJUB 2QKLA 2DYQA 4KHBA 3V5WA 1DYNA 2P0FA 1H10A 2KUQA 3D8EA 1UEFA 2KR0A 1BTNA 1ZC4B 2D9XA 2H7EA 2I5FA 1M7EA 2KUPA 1BAKA 2RLOA 1V88A 5DI9B 2EMSA 2YS5A 5CLQB 1FHXA 5C6RA 1B55A 5M4YB 4PNKA 5IRSA 2P0HA 1EGXA 1NTYA 2G35A 2Z14A 2DN6A 2L1CA 2RGNB 2Z59A 4WVFB 4EMOA 4HAUB 4F7GA 1PFJA 1UNRA 1ZYIA 4P7IA 5D3XA 1W1GA 5J3YA 3T06A 4MT7A 2D2QA 1U5GA 1DDVA 4F7UP 4DXAB 3DXCA 1BWNA 1SHCA 2K00A 3A8QA 2YF0A 1KI1B 1FAOA 3IVFA 1Z87A 3A98B 4F7HA 2XQNM 2MDXA 2Z0OA 1U5DA 4HDQA 3KSYA 1MAIA 3PSCA 2I1JA 1ZM0A 2CRFA 3DCXA 1WG7A 2COFA 3PG7A 1OMWA 3SUZA 3U12A 1XR0B 2YRYA 3FSSA 1WGUA 1LW3A 1V5PA 5HE2A 2P0DA 2AEHA 2EJ8A 2LOZA 1LB1A 4DIXA 1ZVRA 4YONA 5C16A 3FM8C 4WJ7A 2VKIA 3FVCA 2D4QA 2N23A 4DX8A 2GCLA 1GC6A 2DA0A 2YSZA 2DKPA 4A5KA 1FHOA 5DHFB 1IRSA 4A6FA 2ELAA 4CHMA 1MIZB 5C5BB 5JHHA 4A6KA 1WVHA 3BJIA 5KQ1A 3AU5A 2OTXA 5I2MA 2J0JA 4L1RA 2YT2A 2COAA 2DLWA 2ROVA 3ZVRA 3TW1A 2JP2A 2D9ZA 2DFKA 1XD4A 4HAWB 2H7DA 4HB0B 4TYZA 1WJ1A 2LKOA 2KGXB 2D10A 4IFSA 4TKNA 3A8PA 4GNKB 2M38A 1H4RA 1PMSA 3DXEA 4C0AA 2QKMA 5KQ4A 4HSIA 1Y19B 4DBBA 3X23A 4GOUA 1I7AA 4DX90 5JLJB 1AWEA 5I2SA 1WI1A 1V5MA 1FGZA 2DTCA 3HK0A 1M7RA 3KY9A 4IAPA 4Z2MB 2Z4DA 2VRWB 2YT0A 4GN1A 4HAXB 1ISNA 2W2XC 4EKUA 1MKEA 3FEHA 2L2IA 2N0YA 5LOPB 2MKRA 1EAZA 3P7ZA 2R09A 3VIAA 1FHWA 1NU2A 1XODA 3GYPA 1RJ2A 4QJ3B 4Y94A 5CLLB 4YL8A 2D9WA 3B77A 2DHKA 2RVBB 2YT1A 3UZTA 1FOEA 3HW2B 4WSFA 4PQ0A 4K17A 1TJ6A 5J3TA 2UZRA 2EC1A 3QWMA 3U8ZA 3OANA 2UZSA 2LULA 4EJNA 3DXDA 1XCGA 1DROA 1TQZA 2GCJA 3PVUA 1MI1A 2K2UA 3WA0A 4D6WA 4KHBB 2J0KA 2I5CA 2YVCA 3ODOA 1UPQA 2Y8GA 2R2YA 1QC6A 1OQNA 3PVLA 3SO6A 1W1DA 4NSWA 3F5RA 5JP4A 4HATB 4KHAA 2Q13A 3ODWA 3A58A 1U2BA 5JHGA 3TO1A 4Z2NA 4HB2B 1UPRA 2I1KA 1RRPB 3ULCA 2RRFA 4HAVB 1P5TA 3LJUX 4OT1A 5HE3A 4QJ4B 5D27A 1GG3A 2V76A 1MK9B 2D9VA 3MPXA 1OY2A 2K49A 2GS0A 1NI2A 1T77A 4HAYB 1MIXA 1P3RA 1J19A 1U5EA 2RSGA 4HB3B 1J0WA 4ZRIA 3TFMA 1U29A 1V89A 2M14A 2RUKB 3CIKA 2D9YA 4CYEA 3SV1A 2CODA 1QQGA 4GPTB 1N3HA 3G9WA 3CXBB 4QJ5B 3NWDA 1MK7B 3KZ1A 2LYDA 4HHVA 2D11A 1K5GB 2W2XD 1I2HA 2DKQA 2RNRB 1U5FA 3NWAA 1DDWA 2KCJA 4IOYX 2YS3A 1Y5OA 2NMBA 4GMXB 1SGHA 2P8VA 1BTKA 3ULBA 4HDOA 2BCJA 2GJYA 2K2JA 4MK0A 2COCA 1WJMA 2LG1A 2Z0QA 1X1FA 3KRXA 3NWFA 3O96A 3KRWA 2DHJA 3D8FA 1X05A 1EF1A 2MWNB 1GC7A 2DX1A 2ROZB 1KZ7A 2Y8FA 3TVVA 2HE7A 5D3WA 2MFQA 2Z13A 4L6EA 1AQCA 1PLSA 3GYOA 5DHAB 2CY4A 3PVWA 4A6FB 2E2XA 3ML4A 4NY0A 5EFXA 2IFSA 3HQCA 1X11A 1KZGA 4B6HA 5C79A 2CY5A 1P6SA 2FJLA 3ODXA 5DH9B 2J59M 4CSQA 4CHJA 3AJ4A 3RCPA 1X86A 3PP2A 1MPHA 2HTHB 3MDBC 3ZDTA 5KCVA 1UNQA 4H8SA 2KIGA 1V5UA 2OQBA 2NZ8B 2LOXA 4K2OA 3AU4A 4HAZB 4GZUA 5HE0A 4GXBA 3HIEA 1DDMA 5D3YA 3SNHA 2X18A 2EMTA 1W1HA 1K5DB 5LONB 3VOQA 5C5BA 1UNPA 4KAXB 2GUMA 1XKEA 3PZDA 3D8DA 4QXAB 3F0WA 5DIFB 4KHOA 2W2WA 1FGYA 4HB4B 4XWXA 2Y7BA 5L81A 3NW8A 1X1GA 2NBVA 1FB8A 1NTVA 5HE1A 3PEGA 3SYXA 3U7DA 1TXDA 2AL6A 5GOWB 1ZSQA 4ZRJA 1V61A 3WYFB
chains in the Genus database with same CATH topology
2DX5A 1ZC3B 1E5WA 1Q67A 3N7CA 3NSUA 1EVHA 3TCAA 5J3QA 2Z0PA 4GMVA 2ADZA 2DYNA 3P6AA 3QBVB 4D0NB 4K2PA 2ELBA 4A6HA 2J0MA 2IYBA 3BINA 4MY6A 3QIJA 5FI0A 2PZ1A 2DHIA 4KVGB 2VSZA 3M1IB 1DBHA 2UVMA 1WGQA 1U27A 2YS1A 5FI1A 4K81A 4BBKA 2ZPYA 5D3VA 2R0DA 2CAYA 4ZRKA 1XX0A 2QKLA 2DYQA 3V5WA 1DYNA 2P0FA 1H10A 3D8EA 1UEFA 1BTNA 1ZC4B 2D9XA 2H7EA 2I5FA 1M7EA 2KUPA 1BAKA 2RLOA 1V88A 5DI9B 2EMSA 2YS5A 5CLQB 1FHXA 5C6RA 1B55A 4PNKA 2P0HA 1EGXA 1NTYA 2G35A 2DN6A 2L1CA 2RGNB 4WVFB 4EMOA 4HAUB 4F7GA 1PFJA 1UNRA 4P7IA 5D3XA 1W1GA 5J3YA 3T06A 4MT7A 2D2QA 1U5GA 1DDVA 4F7UP 4DXAB 3DXCA 1BWNA 1SHCA 2K00A 3A8QA 2YF0A 1KI1B 1FAOA 3IVFA 1Z87A 3A98B 4F7HA 2XQNM 2MDXA 2Z0OA 1U5DA 4HDQA 3KSYA 1MAIA 3PSCA 2I1JA 1ZM0A 2CRFA 1WG7A 2COFA 3PG7A 1OMWA 3SUZA 1XR0B 2YRYA 3FSSA 1WGUA 1LW3A 1V5PA 5HE2A 2P0DA 2AEHA 2EJ8A 2LOZA 1LB1A 1ZVRA 4YONA 5C16A 3FM8C 4WJ7A 2VKIA 2D4QA 2N23A 4DX8A 2GCLA 1GC6A 2DA0A 2YSZA 2DKPA 4A5KA 1FHOA 5DHFB 1IRSA 4A6FA 2ELAA 4CHMA 1MIZB 5C5BB 5JHHA 4A6KA 1WVHA 3BJIA 5KQ1A 3AU5A 2OTXA 2J0JA 2COAA 2DLWA 2ROVA 3ZVRA 3TW1A 2JP2A 2D9ZA 2DFKA 1XD4A 4HAWB 2H7DA 4HB0B 4TYZA 1WJ1A 2LKOA 2KGXB 2D10A 4IFSA 4TKNA 3A8PA 2M38A 1H4RA 1PMSA 3DXEA 4C0AA 2QKMA 5KQ4A 1Y19B 4DBBA 3X23A 1I7AA 4DX90 5JLJB 1AWEA 1WI1A 1V5MA 1FGZA 2DTCA 3HK0A 1M7RA 3KY9A 4IAPA 4Z2MB 2VRWB 2YT0A 4GN1A 4HAXB 1ISNA 2W2XC 4EKUA 1MKEA 3FEHA 2L2IA 2N0YA 5LOPB 2MKRA 1EAZA 3P7ZA 2R09A 3VIAA 1FHWA 1NU2A 1XODA 3GYPA 1RJ2A 4Y94A 5CLLB 4YL8A 2D9WA 2DHKA 2RVBB 2YT1A 3UZTA 1FOEA 3HW2B 4WSFA 4PQ0A 4K17A 1TJ6A 5J3TA 2UZRA 2EC1A 3QWMA 3U8ZA 3OANA 2UZSA 2LULA 4EJNA 3DXDA 1XCGA 1DROA 1TQZA 2GCJA 3PVUA 2K2UA 3WA0A 4KHBB 2J0KA 2I5CA 2YVCA 3ODOA 1UPQA 2Y8GA 1QC6A 1OQNA 3PVLA 3SO6A 1W1DA 4NSWA 3F5RA 5JP4A 4HATB 4KHAA 2Q13A 3ODWA 1U2BA 5JHGA 3TO1A 4Z2NA 4HB2B 1UPRA 2I1KA 1RRPB 3ULCA 4HAVB 1P5TA 3LJUX 5HE3A 5D27A 1GG3A 2V76A 1MK9B 2D9VA 3MPXA 1OY2A 2GS0A 1NI2A 4HAYB 1MIXA 1P3RA 1J19A 1U5EA 2RSGA 4HB3B 1J0WA 4ZRIA 3TFMA 1U29A 1V89A 2M14A 2RUKB 3CIKA 2D9YA 4CYEA 3SV1A 2CODA 1QQGA 4GPTB 1N3HA 3G9WA 3CXBB 1MK7B 3KZ1A 2LYDA 4HHVA 2D11A 1K5GB 2W2XD 1I2HA 2DKQA 2RNRB 1U5FA 1DDWA 2KCJA 4IOYX 2YS3A 1Y5OA 2NMBA 4GMXB 1SGHA 2P8VA 1BTKA 3ULBA 4HDOA 2BCJA 2GJYA 2K2JA 4MK0A 2COCA 1WJMA 2LG1A 2Z0QA 1X1FA 3KRXA 3O96A 3KRWA 2DHJA 3D8FA 1X05A 1EF1A 2MWNB 1GC7A 2DX1A 2ROZB 1KZ7A 2Y8FA 3TVVA 2HE7A 5D3WA 2MFQA 4L6EA 1AQCA 1PLSA 3GYOA 5DHAB 2CY4A 3PVWA 4A6FB 2E2XA 3ML4A 4NY0A 5EFXA 2IFSA 3HQCA 1X11A 1KZGA 4B6HA 5C79A 2CY5A 1P6SA 2FJLA 3ODXA 5DH9B 2J59M 4CHJA 3AJ4A 3RCPA 1X86A 3PP2A 1MPHA 2HTHB 3MDBC 3ZDTA 5KCVA 1UNQA 4H8SA 1V5UA 2OQBA 2NZ8B 2LOXA 4K2OA 3AU4A 4HAZB 4GZUA 5HE0A 4GXBA 1DDMA 5D3YA 3SNHA 2X18A 2EMTA 1W1HA 1K5DB 5LONB 3VOQA 5C5BA 1UNPA 4KAXB 1XKEA 3PZDA 3D8DA 3F0WA 5DIFB 4KHOA 2W2WA 1FGYA 4HB4B 4XWXA 2Y7BA 5L81A 1X1GA 1FB8A 1NTVA 5HE1A 3PEGA 3SYXA 3U7DA 1TXDA 2AL6A 5GOWB 1ZSQA 4ZRJA 1V61A 3WYFB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DX5 A;  1ZC3 B;  1E5W A;  1Q67 A;  3N7C A;  3NSU A;  1EVH A;  3TCA A;  5J3Q A;  2Z0P A;  4GMV A;  2ADZ A;  2DYN A;  3P6A A;  3QBV B;  4D0N B;  4K2P A;  2ELB A;  4A6H A;  2J0M A;  2IYB A;  3BIN A;  4MY6 A;  3QIJ A;  5FI0 A;  2PZ1 A;  2DHI A;  4KVG B;  2VSZ A;  3M1I B;  1DBH A;  2UVM A;  1WGQ A;  1U27 A;  2YS1 A;  5FI1 A;  4K81 A;  4BBK A;  2ZPY A;  5D3V A;  2R0D A;  2CAY A;  4ZRK A;  1XX0 A;  2QKL A;  2DYQ A;  3V5W A;  1DYN A;  2P0F A;  1H10 A;  3D8E A;  1UEF A;  1BTN A;  1ZC4 B;  2D9X A;  2H7E A;  2I5F A;  1M7E A;  2KUP A;  1BAK A;  2RLO A;  1V88 A;  5DI9 B;  2EMS A;  2YS5 A;  5CLQ B;  1FHX A;  5C6R A;  1B55 A;  4PNK A;  2P0H A;  1EGX A;  1NTY A;  2G35 A;  2DN6 A;  2L1C A;  2RGN B;  4WVF B;  4EMO A;  4HAU B;  4F7G A;  1PFJ A;  1UNR A;  4P7I A;  5D3X A;  1W1G A;  5J3Y A;  3T06 A;  4MT7 A;  2D2Q A;  1U5G A;  1DDV A;  4F7U P;  4DXA B;  3DXC A;  1BWN A;  1SHC A;  2K00 A;  3A8Q A;  2YF0 A;  1KI1 B;  1FAO A;  3IVF A;  1Z87 A;  3A98 B;  4F7H A;  2XQN M;  2MDX A;  2Z0O A;  1U5D A;  4HDQ A;  3KSY A;  1MAI A;  3PSC A;  2I1J A;  1ZM0 A;  2CRF A;  1WG7 A;  2COF A;  3PG7 A;  1OMW A;  3SUZ A;  1XR0 B;  2YRY A;  3FSS A;  1WGU A;  1LW3 A;  1V5P A;  5HE2 A;  2P0D A;  2AEH A;  2EJ8 A;  2LOZ A;  1LB1 A;  1ZVR A;  4YON A;  5C16 A;  3FM8 C;  4WJ7 A;  2VKI A;  2D4Q A;  2N23 A;  4DX8 A;  2GCL A;  1GC6 A;  2DA0 A;  2YSZ A;  2DKP A;  4A5K A;  1FHO A;  5DHF B;  1IRS A;  4A6F A;  2ELA A;  4CHM A;  1MIZ B;  5C5B B;  5JHH A;  4A6K A;  1WVH A;  3BJI A;  5KQ1 A;  3AU5 A;  2OTX A;  2J0J A;  2COA A;  2DLW A;  2ROV A;  3ZVR A;  3TW1 A;  2JP2 A;  2D9Z A;  2DFK A;  1XD4 A;  4HAW B;  2H7D A;  4HB0 B;  4TYZ A;  1WJ1 A;  2LKO A;  2KGX B;  2D10 A;  4IFS A;  4TKN A;  3A8P A;  2M38 A;  1H4R A;  1PMS A;  3DXE A;  4C0A A;  2QKM A;  5KQ4 A;  1Y19 B;  4DBB A;  3X23 A;  1I7A A;  4DX9 0;  5JLJ B;  1AWE A;  1WI1 A;  1V5M A;  1FGZ A;  2DTC A;  3HK0 A;  1M7R A;  3KY9 A;  4IAP A;  4Z2M B;  2VRW B;  2YT0 A;  4GN1 A;  4HAX B;  1ISN A;  2W2X C;  4EKU A;  1MKE A;  3FEH A;  2L2I A;  2N0Y A;  5LOP B;  2MKR A;  1EAZ A;  3P7Z A;  2R09 A;  3VIA A;  1FHW A;  1NU2 A;  1XOD A;  3GYP A;  1RJ2 A;  4Y94 A;  5CLL B;  4YL8 A;  2D9W A;  2DHK A;  2RVB B;  2YT1 A;  3UZT A;  1FOE A;  3HW2 B;  4WSF A;  4PQ0 A;  4K17 A;  1TJ6 A;  5J3T A;  2UZR A;  2EC1 A;  3QWM A;  3U8Z A;  3OAN A;  2UZS A;  2LUL A;  4EJN A;  3DXD A;  1XCG A;  1DRO A;  1TQZ A;  2GCJ A;  3PVU A;  2K2U A;  3WA0 A;  4KHB B;  2J0K A;  2I5C A;  2YVC A;  3ODO A;  1UPQ A;  2Y8G A;  1QC6 A;  1OQN A;  3PVL A;  3SO6 A;  1W1D A;  4NSW A;  3F5R A;  5JP4 A;  4HAT B;  4KHA A;  2Q13 A;  3ODW A;  1U2B A;  5JHG A;  3TO1 A;  4Z2N A;  4HB2 B;  1UPR A;  2I1K A;  1RRP B;  3ULC A;  4HAV B;  1P5T A;  3LJU X;  5HE3 A;  5D27 A;  1GG3 A;  2V76 A;  1MK9 B;  2D9V A;  3MPX A;  1OY2 A;  2GS0 A;  1NI2 A;  4HAY B;  1MIX A;  1P3R A;  1J19 A;  1U5E A;  2RSG A;  4HB3 B;  1J0W A;  4ZRI A;  3TFM A;  1U29 A;  1V89 A;  2M14 A;  2RUK B;  3CIK A;  2D9Y A;  4CYE A;  3SV1 A;  2COD A;  1QQG A;  4GPT B;  1N3H A;  3G9W A;  3CXB B;  1MK7 B;  3KZ1 A;  2LYD A;  4HHV A;  2D11 A;  1K5G B;  2W2X D;  1I2H A;  2DKQ A;  2RNR B;  1U5F A;  1DDW A;  2KCJ A;  4IOY X;  2YS3 A;  1Y5O A;  2NMB A;  4GMX B;  1SGH A;  2P8V A;  1BTK A;  3ULB A;  4HDO A;  2BCJ A;  2GJY A;  2K2J A;  4MK0 A;  2COC A;  1WJM A;  2LG1 A;  2Z0Q A;  1X1F A;  3KRX A;  3O96 A;  3KRW A;  2DHJ A;  3D8F A;  1X05 A;  1EF1 A;  2MWN B;  1GC7 A;  2DX1 A;  2ROZ B;  1KZ7 A;  2Y8F A;  3TVV A;  2HE7 A;  5D3W A;  2MFQ A;  4L6E A;  1AQC A;  1PLS A;  3GYO A;  5DHA B;  2CY4 A;  3PVW A;  4A6F B;  2E2X A;  3ML4 A;  4NY0 A;  5EFX A;  2IFS A;  3HQC A;  1X11 A;  1KZG A;  4B6H A;  5C79 A;  2CY5 A;  1P6S A;  2FJL A;  3ODX A;  5DH9 B;  2J59 M;  4CHJ A;  3AJ4 A;  3RCP A;  1X86 A;  3PP2 A;  1MPH A;  2HTH B;  3MDB C;  3ZDT A;  5KCV A;  1UNQ A;  4H8S A;  1V5U A;  2OQB A;  2NZ8 B;  2LOX A;  4K2O A;  3AU4 A;  4HAZ B;  4GZU A;  5HE0 A;  4GXB A;  1DDM A;  5D3Y A;  3SNH A;  2X18 A;  2EMT A;  1W1H A;  1K5D B;  5LON B;  3VOQ A;  5C5B A;  1UNP A;  4KAX B;  1XKE A;  3PZD A;  3D8D A;  3F0W A;  5DIF B;  4KHO A;  2W2W A;  1FGY A;  4HB4 B;  4XWX A;  2Y7B A;  5L81 A;  1X1G A;  1FB8 A;  1NTV A;  5HE1 A;  3PEG A;  3SYX A;  3U7D A;  1TXD A;  2AL6 A;  5GOW B;  1ZSQ A;  4ZRJ A;  1V61 A;  3WYF B; 
#chains in the Genus database with same CATH topology
 2DX5 A;  1ZC3 B;  1E5W A;  1Q67 A;  3N7C A;  3NSU A;  1EVH A;  3TCA A;  5J3Q A;  2Z0P A;  3HSA A;  4GMV A;  2ADZ A;  2DYN A;  3P6A A;  3QBV B;  4D0N B;  4K2P A;  3OHM B;  2ELB A;  4A6H A;  2J0M A;  2IYB A;  3BIN A;  4MY6 A;  3QIJ A;  5FI0 A;  2PZ1 A;  2DHI A;  4KVG B;  2VSZ A;  3M1I B;  1DBH A;  2ZKM X;  2UVM A;  1WGQ A;  1U27 A;  4OSN A;  2YS1 A;  5FI1 A;  4K81 A;  4BBK A;  2ZPY A;  5D3V A;  2KIE A;  2R0D A;  2K8E A;  5LG4 B;  2CAY A;  4ZRK A;  1XX0 A;  2FJU B;  2QKL A;  2DYQ A;  4KHB A;  3V5W A;  1DYN A;  2P0F A;  1H10 A;  2KUQ A;  3D8E A;  1UEF A;  2KR0 A;  1BTN A;  1ZC4 B;  2D9X A;  2H7E A;  2I5F A;  1M7E A;  2KUP A;  1BAK A;  2RLO A;  1V88 A;  5DI9 B;  2EMS A;  2YS5 A;  5CLQ B;  1FHX A;  5C6R A;  1B55 A;  5M4Y B;  4PNK A;  5IRS A;  2P0H A;  1EGX A;  1NTY A;  2G35 A;  2Z14 A;  2DN6 A;  2L1C A;  2RGN B;  2Z59 A;  4WVF B;  4EMO A;  4HAU B;  4F7G A;  1PFJ A;  1UNR A;  1ZYI A;  4P7I A;  5D3X A;  1W1G A;  5J3Y A;  3T06 A;  4MT7 A;  2D2Q A;  1U5G A;  1DDV A;  4F7U P;  4DXA B;  3DXC A;  1BWN A;  1SHC A;  2K00 A;  3A8Q A;  2YF0 A;  1KI1 B;  1FAO A;  3IVF A;  1Z87 A;  3A98 B;  4F7H A;  2XQN M;  2MDX A;  2Z0O A;  1U5D A;  4HDQ A;  3KSY A;  1MAI A;  3PSC A;  2I1J A;  1ZM0 A;  2CRF A;  3DCX A;  1WG7 A;  2COF A;  3PG7 A;  1OMW A;  3SUZ A;  3U12 A;  1XR0 B;  2YRY A;  3FSS A;  1WGU A;  1LW3 A;  1V5P A;  5HE2 A;  2P0D A;  2AEH A;  2EJ8 A;  2LOZ A;  1LB1 A;  4DIX A;  1ZVR A;  4YON A;  5C16 A;  3FM8 C;  4WJ7 A;  2VKI A;  3FVC A;  2D4Q A;  2N23 A;  4DX8 A;  2GCL A;  1GC6 A;  2DA0 A;  2YSZ A;  2DKP A;  4A5K A;  1FHO A;  5DHF B;  1IRS A;  4A6F A;  2ELA A;  4CHM A;  1MIZ B;  5C5B B;  5JHH A;  4A6K A;  1WVH A;  3BJI A;  5KQ1 A;  3AU5 A;  2OTX A;  5I2M A;  2J0J A;  4L1R A;  2YT2 A;  2COA A;  2DLW A;  2ROV A;  3ZVR A;  3TW1 A;  2JP2 A;  2D9Z A;  2DFK A;  1XD4 A;  4HAW B;  2H7D A;  4HB0 B;  4TYZ A;  1WJ1 A;  2LKO A;  2KGX B;  2D10 A;  4IFS A;  4TKN A;  3A8P A;  4GNK B;  2M38 A;  1H4R A;  1PMS A;  3DXE A;  4C0A A;  2QKM A;  5KQ4 A;  4HSI A;  1Y19 B;  4DBB A;  3X23 A;  4GOU A;  1I7A A;  4DX9 0;  5JLJ B;  1AWE A;  5I2S A;  1WI1 A;  1V5M A;  1FGZ A;  2DTC A;  3HK0 A;  1M7R A;  3KY9 A;  4IAP A;  4Z2M B;  2Z4D A;  2VRW B;  2YT0 A;  4GN1 A;  4HAX B;  1ISN A;  2W2X C;  4EKU A;  1MKE A;  3FEH A;  2L2I A;  2N0Y A;  5LOP B;  2MKR A;  1EAZ A;  3P7Z A;  2R09 A;  3VIA A;  1FHW A;  1NU2 A;  1XOD A;  3GYP A;  1RJ2 A;  4QJ3 B;  4Y94 A;  5CLL B;  4YL8 A;  2D9W A;  3B77 A;  2DHK A;  2RVB B;  2YT1 A;  3UZT A;  1FOE A;  3HW2 B;  4WSF A;  4PQ0 A;  4K17 A;  1TJ6 A;  5J3T A;  2UZR A;  2EC1 A;  3QWM A;  3U8Z A;  3OAN A;  2UZS A;  2LUL A;  4EJN A;  3DXD A;  1XCG A;  1DRO A;  1TQZ A;  2GCJ A;  3PVU A;  1MI1 A;  2K2U A;  3WA0 A;  4D6W A;  4KHB B;  2J0K A;  2I5C A;  2YVC A;  3ODO A;  1UPQ A;  2Y8G A;  2R2Y A;  1QC6 A;  1OQN A;  3PVL A;  3SO6 A;  1W1D A;  4NSW A;  3F5R A;  5JP4 A;  4HAT B;  4KHA A;  2Q13 A;  3ODW A;  3A58 A;  1U2B A;  5JHG A;  3TO1 A;  4Z2N A;  4HB2 B;  1UPR A;  2I1K A;  1RRP B;  3ULC A;  2RRF A;  4HAV B;  1P5T A;  3LJU X;  4OT1 A;  5HE3 A;  4QJ4 B;  5D27 A;  1GG3 A;  2V76 A;  1MK9 B;  2D9V A;  3MPX A;  1OY2 A;  2K49 A;  2GS0 A;  1NI2 A;  1T77 A;  4HAY B;  1MIX A;  1P3R A;  1J19 A;  1U5E A;  2RSG A;  4HB3 B;  1J0W A;  4ZRI A;  3TFM A;  1U29 A;  1V89 A;  2M14 A;  2RUK B;  3CIK A;  2D9Y A;  4CYE A;  3SV1 A;  2COD A;  1QQG A;  4GPT B;  1N3H A;  3G9W A;  3CXB B;  4QJ5 B;  3NWD A;  1MK7 B;  3KZ1 A;  2LYD A;  4HHV A;  2D11 A;  1K5G B;  2W2X D;  1I2H A;  2DKQ A;  2RNR B;  1U5F A;  3NWA A;  1DDW A;  2KCJ A;  4IOY X;  2YS3 A;  1Y5O A;  2NMB A;  4GMX B;  1SGH A;  2P8V A;  1BTK A;  3ULB A;  4HDO A;  2BCJ A;  2GJY A;  2K2J A;  4MK0 A;  2COC A;  1WJM A;  2LG1 A;  2Z0Q A;  1X1F A;  3KRX A;  3NWF A;  3O96 A;  3KRW A;  2DHJ A;  3D8F A;  1X05 A;  1EF1 A;  2MWN B;  1GC7 A;  2DX1 A;  2ROZ B;  1KZ7 A;  2Y8F A;  3TVV A;  2HE7 A;  5D3W A;  2MFQ A;  2Z13 A;  4L6E A;  1AQC A;  1PLS A;  3GYO A;  5DHA B;  2CY4 A;  3PVW A;  4A6F B;  2E2X A;  3ML4 A;  4NY0 A;  5EFX A;  2IFS A;  3HQC A;  1X11 A;  1KZG A;  4B6H A;  5C79 A;  2CY5 A;  1P6S A;  2FJL A;  3ODX A;  5DH9 B;  2J59 M;  4CSQ A;  4CHJ A;  3AJ4 A;  3RCP A;  1X86 A;  3PP2 A;  1MPH A;  2HTH B;  3MDB C;  3ZDT A;  5KCV A;  1UNQ A;  4H8S A;  2KIG A;  1V5U A;  2OQB A;  2NZ8 B;  2LOX A;  4K2O A;  3AU4 A;  4HAZ B;  4GZU A;  5HE0 A;  4GXB A;  3HIE A;  1DDM A;  5D3Y A;  3SNH A;  2X18 A;  2EMT A;  1W1H A;  1K5D B;  5LON B;  3VOQ A;  5C5B A;  1UNP A;  4KAX B;  2GUM A;  1XKE A;  3PZD A;  3D8D A;  4QXA B;  3F0W A;  5DIF B;  4KHO A;  2W2W A;  1FGY A;  4HB4 B;  4XWX A;  2Y7B A;  5L81 A;  3NW8 A;  1X1G A;  2NBV A;  1FB8 A;  1NTV A;  5HE1 A;  3PEG A;  3SYX A;  3U7D A;  1TXD A;  2AL6 A;  5GOW B;  1ZSQ A;  4ZRJ A;  1V61 A;  3WYF B; 
#chains in the Genus database with same CATH homology
 2DX5 A;  1ZC3 B;  1E5W A;  1Q67 A;  3N7C A;  3NSU A;  1EVH A;  3TCA A;  5J3Q A;  2Z0P A;  4GMV A;  2ADZ A;  2DYN A;  3P6A A;  3QBV B;  4D0N B;  4K2P A;  2ELB A;  4A6H A;  2J0M A;  2IYB A;  3BIN A;  4MY6 A;  3QIJ A;  5FI0 A;  2PZ1 A;  2DHI A;  4KVG B;  2VSZ A;  3M1I B;  1DBH A;  2UVM A;  1WGQ A;  1U27 A;  2YS1 A;  5FI1 A;  4K81 A;  4BBK A;  2ZPY A;  5D3V A;  2R0D A;  2CAY A;  4ZRK A;  1XX0 A;  2QKL A;  2DYQ A;  3V5W A;  1DYN A;  2P0F A;  1H10 A;  3D8E A;  1UEF A;  1BTN A;  1ZC4 B;  2D9X A;  2H7E A;  2I5F A;  1M7E A;  2KUP A;  1BAK A;  2RLO A;  1V88 A;  5DI9 B;  2EMS A;  2YS5 A;  5CLQ B;  1FHX A;  5C6R A;  1B55 A;  4PNK A;  2P0H A;  1EGX A;  1NTY A;  2G35 A;  2DN6 A;  2L1C A;  2RGN B;  4WVF B;  4EMO A;  4HAU B;  4F7G A;  1PFJ A;  1UNR A;  4P7I A;  5D3X A;  1W1G A;  5J3Y A;  3T06 A;  4MT7 A;  2D2Q A;  1U5G A;  1DDV A;  4F7U P;  4DXA B;  3DXC A;  1BWN A;  1SHC A;  2K00 A;  3A8Q A;  2YF0 A;  1KI1 B;  1FAO A;  3IVF A;  1Z87 A;  3A98 B;  4F7H A;  2XQN M;  2MDX A;  2Z0O A;  1U5D A;  4HDQ A;  3KSY A;  1MAI A;  3PSC A;  2I1J A;  1ZM0 A;  2CRF A;  1WG7 A;  2COF A;  3PG7 A;  1OMW A;  3SUZ A;  1XR0 B;  2YRY A;  3FSS A;  1WGU A;  1LW3 A;  1V5P A;  5HE2 A;  2P0D A;  2AEH A;  2EJ8 A;  2LOZ A;  1LB1 A;  1ZVR A;  4YON A;  5C16 A;  3FM8 C;  4WJ7 A;  2VKI A;  2D4Q A;  2N23 A;  4DX8 A;  2GCL A;  1GC6 A;  2DA0 A;  2YSZ A;  2DKP A;  4A5K A;  1FHO A;  5DHF B;  1IRS A;  4A6F A;  2ELA A;  4CHM A;  1MIZ B;  5C5B B;  5JHH A;  4A6K A;  1WVH A;  3BJI A;  5KQ1 A;  3AU5 A;  2OTX A;  2J0J A;  2COA A;  2DLW A;  2ROV A;  3ZVR A;  3TW1 A;  2JP2 A;  2D9Z A;  2DFK A;  1XD4 A;  4HAW B;  2H7D A;  4HB0 B;  4TYZ A;  1WJ1 A;  2LKO A;  2KGX B;  2D10 A;  4IFS A;  4TKN A;  3A8P A;  2M38 A;  1H4R A;  1PMS A;  3DXE A;  4C0A A;  2QKM A;  5KQ4 A;  1Y19 B;  4DBB A;  3X23 A;  1I7A A;  4DX9 0;  5JLJ B;  1AWE A;  1WI1 A;  1V5M A;  1FGZ A;  2DTC A;  3HK0 A;  1M7R A;  3KY9 A;  4IAP A;  4Z2M B;  2VRW B;  2YT0 A;  4GN1 A;  4HAX B;  1ISN A;  2W2X C;  4EKU A;  1MKE A;  3FEH A;  2L2I A;  2N0Y A;  5LOP B;  2MKR A;  1EAZ A;  3P7Z A;  2R09 A;  3VIA A;  1FHW A;  1NU2 A;  1XOD A;  3GYP A;  1RJ2 A;  4Y94 A;  5CLL B;  4YL8 A;  2D9W A;  2DHK A;  2RVB B;  2YT1 A;  3UZT A;  1FOE A;  3HW2 B;  4WSF A;  4PQ0 A;  4K17 A;  1TJ6 A;  5J3T A;  2UZR A;  2EC1 A;  3QWM A;  3U8Z A;  3OAN A;  2UZS A;  2LUL A;  4EJN A;  3DXD A;  1XCG A;  1DRO A;  1TQZ A;  2GCJ A;  3PVU A;  2K2U A;  3WA0 A;  4KHB B;  2J0K A;  2I5C A;  2YVC A;  3ODO A;  1UPQ A;  2Y8G A;  1QC6 A;  1OQN A;  3PVL A;  3SO6 A;  1W1D A;  4NSW A;  3F5R A;  5JP4 A;  4HAT B;  4KHA A;  2Q13 A;  3ODW A;  1U2B A;  5JHG A;  3TO1 A;  4Z2N A;  4HB2 B;  1UPR A;  2I1K A;  1RRP B;  3ULC A;  4HAV B;  1P5T A;  3LJU X;  5HE3 A;  5D27 A;  1GG3 A;  2V76 A;  1MK9 B;  2D9V A;  3MPX A;  1OY2 A;  2GS0 A;  1NI2 A;  4HAY B;  1MIX A;  1P3R A;  1J19 A;  1U5E A;  2RSG A;  4HB3 B;  1J0W A;  4ZRI A;  3TFM A;  1U29 A;  1V89 A;  2M14 A;  2RUK B;  3CIK A;  2D9Y A;  4CYE A;  3SV1 A;  2COD A;  1QQG A;  4GPT B;  1N3H A;  3G9W A;  3CXB B;  1MK7 B;  3KZ1 A;  2LYD A;  4HHV A;  2D11 A;  1K5G B;  2W2X D;  1I2H A;  2DKQ A;  2RNR B;  1U5F A;  1DDW A;  2KCJ A;  4IOY X;  2YS3 A;  1Y5O A;  2NMB A;  4GMX B;  1SGH A;  2P8V A;  1BTK A;  3ULB A;  4HDO A;  2BCJ A;  2GJY A;  2K2J A;  4MK0 A;  2COC A;  1WJM A;  2LG1 A;  2Z0Q A;  1X1F A;  3KRX A;  3O96 A;  3KRW A;  2DHJ A;  3D8F A;  1X05 A;  1EF1 A;  2MWN B;  1GC7 A;  2DX1 A;  2ROZ B;  1KZ7 A;  2Y8F A;  3TVV A;  2HE7 A;  5D3W A;  2MFQ A;  4L6E A;  1AQC A;  1PLS A;  3GYO A;  5DHA B;  2CY4 A;  3PVW A;  4A6F B;  2E2X A;  3ML4 A;  4NY0 A;  5EFX A;  2IFS A;  3HQC A;  1X11 A;  1KZG A;  4B6H A;  5C79 A;  2CY5 A;  1P6S A;  2FJL A;  3ODX A;  5DH9 B;  2J59 M;  4CHJ A;  3AJ4 A;  3RCP A;  1X86 A;  3PP2 A;  1MPH A;  2HTH B;  3MDB C;  3ZDT A;  5KCV A;  1UNQ A;  4H8S A;  1V5U A;  2OQB A;  2NZ8 B;  2LOX A;  4K2O A;  3AU4 A;  4HAZ B;  4GZU A;  5HE0 A;  4GXB A;  1DDM A;  5D3Y A;  3SNH A;  2X18 A;  2EMT A;  1W1H A;  1K5D B;  5LON B;  3VOQ A;  5C5B A;  1UNP A;  4KAX B;  1XKE A;  3PZD A;  3D8D A;  3F0W A;  5DIF B;  4KHO A;  2W2W A;  1FGY A;  4HB4 B;  4XWX A;  2Y7B A;  5L81 A;  1X1G A;  1FB8 A;  1NTV A;  5HE1 A;  3PEG A;  3SYX A;  3U7D A;  1TXD A;  2AL6 A;  5GOW B;  1ZSQ A;  4ZRJ A;  1V61 A;  3WYF B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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