1UNQA

High resolution crystal structure of the pleckstrin homology domain of protein kinase b/akt bound to ins(1,3,4,5)-tetrakisphophate
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
117
structure length
117
Chain Sequence
SMSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
molecule keywords RAC-ALPHA SERINE/THREONINE KINASE
total genus 32
structure length 117
sequence length 117
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2003-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1unqA00
4D0NB 2K2UA 4EKUA 1UNRA 2GJYA 2YVCA 5C6RA 2QKLA 2YRYA 4C0AA 2RNRB 4HDQA 2RLOA 1P3RA 2DLWA 1K5GB 2DHJA 5LONB 3HQCA 1NTVA 3KSYA 2I1JA 1V5MA 2D11A 4CYEA 4HHVA 5GOWB 1TXDA 4H8SA 1SGHA 1FGYA 1MAIA 4HAWB 3KZ1A 4HAVB 4XWXA 5JLJB 1UPQA 2NMBA 1WVHA 3SUZA 4KHOA 1XR0B 3PG7A 1XX0A 4K2PA 1FGZA 2DTCA 3M1IB 1EF1A 2I1KA 1FAOA 2Z0PA 2Y8FA 4GN1A 5C79A 1U5EA 3ZDTA 2X18A 3FSSA 4KHBB 1MIZB 2MFQA 1DDVA 4A6HA 4A6FA 1M7EA 4ZRKA 3HK0A 3CXBB 2LOXA 4CHJA 2P0HA 2DN6A 1ZM0A 1ZSQA 5JP4A 5L81A 2VSZA 2Y8GA 2BCJA 5EFXA 2YS1A 2ELAA 4GZUA 3FEHA 2D9XA 1N3HA 2DHIA 2P8VA 5D27A 2MDXA 2EMSA 2K00A 1I7AA 2KUPA 4MK0A 3NSUA 1X11A 3QBVB 1KI1B 5DHFB 2P0FA 2COFA 1ZC3B 2N23A 2KCJA 1V5PA 3MPXA 1H10A 1BAKA 2CAYA 2N0YA 2YS3A 2DX5A 3U8ZA 1UEFA 5CLQB 4EMOA 3GYPA 4Y94A 2YT1A 2RVBB 2DKQA 2HE7A 3SYXA 1XODA 5FI0A 2P0DA 2ZPYA 1WG7A 4NY0A 4B6HA 4K17A 2DKPA 3ML4A 3F5RA 2L2IA 3TW1A 1U2BA 3A8PA 1Y5OA 2COAA 1XKEA 5D3WA 2Z0QA 3PSCA 3WYFB 3AJ4A 3D8EA 3D8DA 3X23A 3ULBA 1PFJA 2D9VA 3U7DA 2LYDA 1KZGA 5HE0A 5KQ4A 5J3YA 1UNQA 3BJIA 2XQNM 2Y7BA 3F0WA 1XD4A 2AEHA 3PZDA 2ROVA 3QWMA 3OANA 4Z2MB 3DXCA 1U5GA 1M7RA 1U29A 4GXBA 2OTXA 4HAYB 2RGNB 5DIFB 1NU2A 1QQGA 1LB1A 2Q13A 1BWNA 2D9YA 4BBKA 3DXEA 2FJLA 4WJ7A 3SNHA 2GCJA 2LG1A 1WGUA 1H4RA 2Z0OA 1PLSA 1PMSA 4HAZB 4HB2B 1SHCA 1GC6A 1FHWA 2D2QA 4KVGB 1DBHA 2CRFA 1K5DB 2R0DA 2MWNB 1GC7A 2YT0A 3VIAA 2W2XD 3TFMA 1UNPA 2KGXB 1OY2A 4MY6A 1X1GA 1I2HA 1OQNA 4TKNA 2J0JA 5C16A 2GS0A 1DDWA 5JHGA 1DROA 3FM8C 1MKEA 4WVFB 2D4QA 4IAPA 2EC1A 2LULA 2YS5A 4HAXB 4F7GA 1WJMA 4TYZA 2VRWB 2JP2A 2DHKA 4KAXB 4KHAA 4YL8A 2H7DA 4GMVA 1P5TA 3KY9A 2NZ8B 1FB8A 4HB0B 2E2XA 4EJNA 3D8FA 5FI1A 5D3VA 3AU5A 5KQ1A 2VKIA 3ODWA 2R09A 1V89A 2EJ8A 5LOPB 1FOEA 3ODXA 3BINA 1DDMA 3PP2A 2PZ1A 2V76A 1RJ2A 2COCA 3A98B 1MK9B 2D9ZA 3UZTA 1X1FA 1AQCA 2W2XC 3DXDA 4F7UP 3TCAA 1NI2A 1KZ7A 3ZVRA 2ELBA 2ROZB 2M38A 5DI9B 3V5WA 1X86A 1AWEA 4CHMA 3SO6A 5DHAB 4Z2NA 3KRWA 3RCPA 1U27A 4ZRJA 5KCVA 4HDOA 2DX1A 3VOQA 2W2WA 4K2OA 3IVFA 1W1GA 4NSWA 4PNKA 2CY4A 1FHXA 2G35A 3LJUX 2YSZA 1P6SA 4WSFA 2H7EA 1V5UA 2MKRA 1WJ1A 5HE1A 4HATB 2DYNA 1Y19B 5HE3A 3G9WA 1U5FA 1W1HA 3ODOA 2K2JA 4DX90 1MIXA 1DYNA 3T06A 4HB4B 2I5CA 1UPRA 4HAUB 2YF0A 3O96A 2QKMA 1J19A 3AU4A 1QC6A 3WA0A 2LKOA 1RRPB 2IYBA 4ZRIA 5C5BB 1TJ6A 2LOZA 3CIKA 1E5WA 1EVHA 3TVVA 2UZRA 4F7HA 3HW2B 4A5KA 5DH9B 4DBBA 2AL6A 1FHOA 4GMXB 4HB3B 1WGQA 3A8QA 2D10A 2D9WA 4DXAB 5HE2A 2DA0A 4GPTB 2I5FA 1IRSA 1EAZA 2UVMA 3PEGA 3MDBC 2EMTA 1W1DA 2DYQA 4P7IA 2DFKA 1OMWA 1ZVRA 3ULCA 1GG3A 3SV1A 5J3TA 1XCGA 2ADZA 1LW3A 1BTNA 3PVWA 3P7ZA 2CODA 4A6KA 3N7CA 2RUKB 1V88A 2OQBA 1BTKA 3TO1A 1MK7B 1ISNA 1NTYA 2UZSA 4L6EA 3GYOA 1X05A 1MPHA 3PVLA 1EGXA 3KRXA 1Q67A 3QIJA 5D3XA 5C5BA 2HTHB 2J0KA 1Z87A 4IFSA 2L1CA 2M14A 5J3QA 5JHHA 4YONA 4IOYX 2GCLA 3PVUA 1U5DA 2RSGA 2IFSA 2J59M 4DX8A 1TQZA 1B55A 4MT7A 5CLLB 1ZC4B 3P6AA 1WI1A 1V61A 4PQ0A 4A6FB 2J0MA 4K81A 1J0WA 5D3YA 2CY5A
chains in the Genus database with same CATH superfamily
4D0NB 2K2UA 4DIXA 4EKUA 1UNRA 2GJYA 2YVCA 5C6RA 2QKLA 2YRYA 2Z4DA 4C0AA 2RNRB 1T77A 3NW8A 4HDQA 2RLOA 1P3RA 2DLWA 1K5GB 2DHJA 5LONB 3HQCA 1NTVA 3KSYA 2I1JA 1V5MA 2D11A 4CYEA 4HHVA 5GOWB 2K49A 1TXDA 3NWAA 4GNKB 4H8SA 1SGHA 1FGYA 1MAIA 4HAWB 3KZ1A 4HAVB 4XWXA 5JLJB 1UPQA 2NMBA 1WVHA 3SUZA 4KHOA 1XR0B 5I2SA 3PG7A 1XX0A 4K2PA 1FGZA 2DTCA 3M1IB 1EF1A 2I1KA 1FAOA 2Z0PA 2Y8FA 4GN1A 5C79A 1U5EA 3ZDTA 2X18A 3FSSA 4KHBB 1MIZB 2MFQA 1DDVA 4A6HA 4A6FA 1M7EA 4ZRKA 3HK0A 3CXBB 2LOXA 4CHJA 2P0HA 2DN6A 1ZM0A 1ZSQA 5JP4A 5L81A 2VSZA 2Y8GA 2BCJA 5EFXA 2YS1A 2ELAA 4GZUA 3FEHA 2D9XA 1N3HA 3A58A 2DHIA 2P8VA 5D27A 2MDXA 2EMSA 2K00A 1I7AA 2KUPA 4MK0A 4KHBA 3NSUA 2NBVA 1X11A 3QBVB 4QJ3B 1KI1B 5DHFB 2P0FA 2COFA 1ZC3B 2N23A 4QJ5B 2KCJA 1V5PA 3MPXA 1H10A 1BAKA 2CAYA 2N0YA 2YS3A 2DX5A 3U8ZA 1UEFA 5CLQB 4EMOA 3GYPA 3U12A 4Y94A 2YT1A 2RVBB 2DKQA 3B77A 2HE7A 3NWFA 3SYXA 1XODA 5FI0A 2P0DA 2ZPYA 1WG7A 4QXAB 4NY0A 4B6HA 4K17A 2DKPA 3ML4A 3F5RA 2L2IA 3TW1A 1U2BA 3A8PA 1Y5OA 2COAA 1XKEA 5D3WA 2Z0QA 3PSCA 5I2MA 3WYFB 3AJ4A 4OSNA 3D8EA 3D8DA 3X23A 3ULBA 1PFJA 2D9VA 3U7DA 2LYDA 1KZGA 5HE0A 5KQ4A 5J3YA 1UNQA 3BJIA 2XQNM 2Y7BA 3F0WA 1XD4A 2AEHA 3PZDA 2ROVA 3QWMA 2GUMA 3OANA 4Z2MB 3DXCA 1U5GA 1M7RA 1U29A 4GXBA 2OTXA 4HAYB 2RGNB 5DIFB 1NU2A 1QQGA 1LB1A 2Q13A 1BWNA 2D9YA 4BBKA 3DXEA 2FJLA 4WJ7A 3SNHA 2GCJA 2LG1A 1WGUA 1H4RA 2Z0OA 1PLSA 1PMSA 4HAZB 4HB2B 4QJ4B 1SHCA 1GC6A 1FHWA 2D2QA 4KVGB 1DBHA 2CRFA 1K5DB 2R0DA 2MWNB 1GC7A 2YT0A 3VIAA 2W2XD 3TFMA 1UNPA 2KGXB 1OY2A 4MY6A 1X1GA 1I2HA 1OQNA 4TKNA 2J0JA 5C16A 2GS0A 1DDWA 5JHGA 1DROA 3FM8C 1MKEA 4WVFB 2D4QA 2ZKMX 4IAPA 2EC1A 2LULA 2YS5A 4HAXB 4F7GA 1WJMA 4TYZA 2RRFA 2VRWB 2JP2A 2DHKA 4KAXB 4KHAA 4YL8A 2H7DA 4GMVA 1P5TA 2FJUB 3KY9A 2NZ8B 1FB8A 4HB0B 2E2XA 4EJNA 3D8FA 5FI1A 5D3VA 3AU5A 5KQ1A 2VKIA 3ODWA 2R09A 1V89A 2EJ8A 3HSAA 5LOPB 1FOEA 2YT2A 3ODXA 3BINA 1DDMA 3PP2A 2PZ1A 2V76A 1RJ2A 2COCA 3A98B 1MK9B 2D9ZA 3UZTA 1X1FA 1AQCA 3HIEA 2W2XC 3DXDA 4F7UP 2KR0A 3TCAA 1NI2A 1KZ7A 3ZVRA 3OHMB 2ELBA 2ROZB 2M38A 5DI9B 3V5WA 1X86A 1AWEA 4CHMA 3SO6A 5DHAB 4Z2NA 3KRWA 3RCPA 1U27A 4ZRJA 5KCVA 4HDOA 2DX1A 4L1RA 3VOQA 2W2WA 4K2OA 3IVFA 1W1GA 4NSWA 4PNKA 2CY4A 3DCXA 1FHXA 2G35A 3LJUX 2YSZA 1P6SA 4WSFA 2H7EA 1V5UA 2MKRA 1WJ1A 4CSQA 5HE1A 2DYNA 1Y19B 4HATB 5HE3A 3G9WA 1U5FA 1W1HA 3ODOA 2K2JA 4DX90 1MIXA 1DYNA 3T06A 4HB4B 2I5CA 1UPRA 4HAUB 2YF0A 3O96A 2KIEA 2QKMA 1J19A 3AU4A 1QC6A 3WA0A 2LKOA 1RRPB 2IYBA 4GOUA 5IRSA 4ZRIA 5C5BB 1TJ6A 3FVCA 1MI1A 2LOZA 3CIKA 1E5WA 1EVHA 4OT1A 2UZRA 3TVVA 4F7HA 3HW2B 4A5KA 5DH9B 4DBBA 2AL6A 1FHOA 4GMXB 4HB3B 1WGQA 3A8QA 2D10A 2D9WA 4DXAB 4D6WA 5HE2A 2DA0A 4GPTB 2I5FA 1IRSA 1EAZA 2UVMA 3PEGA 5M4YB 3MDBC 2EMTA 1W1DA 1ZYIA 2DYQA 2DFKA 1OMWA 1ZVRA 4P7IA 3ULCA 4HSIA 1GG3A 3SV1A 2K8EA 5J3TA 1XCGA 2ADZA 1LW3A 1BTNA 3PVWA 3P7ZA 2CODA 4A6KA 3N7CA 2RUKB 1V88A 2OQBA 1BTKA 3TO1A 1MK7B 2KIGA 1ISNA 1NTYA 2UZSA 4L6EA 3GYOA 1X05A 1MPHA 3PVLA 1EGXA 3KRXA 1Q67A 3QIJA 5D3XA 3NWDA 5C5BA 2HTHB 2J0KA 1Z87A 4IFSA 2Z59A 2L1CA 2M14A 5LG4B 2R2YA 5J3QA 5JHHA 4YONA 2GCLA 4IOYX 3PVUA 1U5DA 2RSGA 2IFSA 2J59M 4DX8A 1TQZA 2Z13A 1B55A 4MT7A 5CLLB 1ZC4B 3P6AA 1WI1A 1V61A 2KUQA 4PQ0A 4A6FB 2J0MA 4K81A 1J0WA 2Z14A 5D3YA 2CY5A
chains in the Genus database with same CATH topology
4D0NB 2K2UA 4EKUA 1UNRA 2GJYA 2YVCA 5C6RA 2QKLA 2YRYA 4C0AA 2RNRB 4HDQA 2RLOA 1P3RA 2DLWA 1K5GB 2DHJA 5LONB 3HQCA 1NTVA 3KSYA 2I1JA 1V5MA 2D11A 4CYEA 4HHVA 5GOWB 1TXDA 4H8SA 1SGHA 1FGYA 1MAIA 4HAWB 3KZ1A 4HAVB 4XWXA 5JLJB 1UPQA 2NMBA 1WVHA 3SUZA 4KHOA 1XR0B 3PG7A 1XX0A 4K2PA 1FGZA 2DTCA 3M1IB 1EF1A 2I1KA 1FAOA 2Z0PA 2Y8FA 4GN1A 5C79A 1U5EA 3ZDTA 2X18A 3FSSA 4KHBB 1MIZB 2MFQA 1DDVA 4A6HA 4A6FA 1M7EA 4ZRKA 3HK0A 3CXBB 2LOXA 4CHJA 2P0HA 2DN6A 1ZM0A 1ZSQA 5JP4A 5L81A 2VSZA 2Y8GA 2BCJA 5EFXA 2YS1A 2ELAA 4GZUA 3FEHA 2D9XA 1N3HA 2DHIA 2P8VA 5D27A 2MDXA 2EMSA 2K00A 1I7AA 2KUPA 4MK0A 3NSUA 1X11A 3QBVB 1KI1B 5DHFB 2P0FA 2COFA 1ZC3B 2N23A 2KCJA 1V5PA 3MPXA 1H10A 1BAKA 2CAYA 2N0YA 2YS3A 2DX5A 3U8ZA 1UEFA 5CLQB 4EMOA 3GYPA 4Y94A 2YT1A 2RVBB 2DKQA 2HE7A 3SYXA 1XODA 5FI0A 2P0DA 2ZPYA 1WG7A 4NY0A 4B6HA 4K17A 2DKPA 3ML4A 3F5RA 2L2IA 3TW1A 1U2BA 3A8PA 1Y5OA 2COAA 1XKEA 5D3WA 2Z0QA 3PSCA 3WYFB 3AJ4A 3D8EA 3D8DA 3X23A 3ULBA 1PFJA 2D9VA 3U7DA 2LYDA 1KZGA 5HE0A 5KQ4A 5J3YA 1UNQA 3BJIA 2XQNM 2Y7BA 3F0WA 1XD4A 2AEHA 3PZDA 2ROVA 3QWMA 3OANA 4Z2MB 3DXCA 1U5GA 1M7RA 1U29A 4GXBA 2OTXA 4HAYB 2RGNB 5DIFB 1NU2A 1QQGA 1LB1A 2Q13A 1BWNA 2D9YA 4BBKA 3DXEA 2FJLA 4WJ7A 3SNHA 2GCJA 2LG1A 1WGUA 1H4RA 2Z0OA 1PLSA 1PMSA 4HAZB 4HB2B 1SHCA 1GC6A 1FHWA 2D2QA 4KVGB 1DBHA 2CRFA 1K5DB 2R0DA 2MWNB 1GC7A 2YT0A 3VIAA 2W2XD 3TFMA 1UNPA 2KGXB 1OY2A 4MY6A 1X1GA 1I2HA 1OQNA 4TKNA 2J0JA 5C16A 2GS0A 1DDWA 5JHGA 1DROA 3FM8C 1MKEA 4WVFB 2D4QA 4IAPA 2EC1A 2LULA 2YS5A 4HAXB 4F7GA 1WJMA 4TYZA 2VRWB 2JP2A 2DHKA 4KAXB 4KHAA 4YL8A 2H7DA 4GMVA 1P5TA 3KY9A 2NZ8B 1FB8A 4HB0B 2E2XA 4EJNA 3D8FA 5FI1A 5D3VA 3AU5A 5KQ1A 2VKIA 3ODWA 2R09A 1V89A 2EJ8A 5LOPB 1FOEA 3ODXA 3BINA 1DDMA 3PP2A 2PZ1A 2V76A 1RJ2A 2COCA 3A98B 1MK9B 2D9ZA 3UZTA 1X1FA 1AQCA 2W2XC 3DXDA 4F7UP 3TCAA 1NI2A 1KZ7A 3ZVRA 2ELBA 2ROZB 2M38A 5DI9B 3V5WA 1X86A 1AWEA 4CHMA 3SO6A 5DHAB 4Z2NA 3KRWA 3RCPA 1U27A 4ZRJA 5KCVA 4HDOA 2DX1A 3VOQA 2W2WA 4K2OA 3IVFA 1W1GA 4NSWA 4PNKA 2CY4A 1FHXA 2G35A 3LJUX 2YSZA 1P6SA 4WSFA 2H7EA 1V5UA 2MKRA 1WJ1A 5HE1A 4HATB 2DYNA 1Y19B 5HE3A 3G9WA 1U5FA 1W1HA 3ODOA 2K2JA 4DX90 1MIXA 1DYNA 3T06A 4HB4B 2I5CA 1UPRA 4HAUB 2YF0A 3O96A 2QKMA 1J19A 3AU4A 1QC6A 3WA0A 2LKOA 1RRPB 2IYBA 4ZRIA 5C5BB 1TJ6A 2LOZA 3CIKA 1E5WA 1EVHA 3TVVA 2UZRA 4F7HA 3HW2B 4A5KA 5DH9B 4DBBA 2AL6A 1FHOA 4GMXB 4HB3B 1WGQA 3A8QA 2D10A 2D9WA 4DXAB 5HE2A 2DA0A 4GPTB 2I5FA 1IRSA 1EAZA 2UVMA 3PEGA 3MDBC 2EMTA 1W1DA 2DYQA 4P7IA 2DFKA 1OMWA 1ZVRA 3ULCA 1GG3A 3SV1A 5J3TA 1XCGA 2ADZA 1LW3A 1BTNA 3PVWA 3P7ZA 2CODA 4A6KA 3N7CA 2RUKB 1V88A 2OQBA 1BTKA 3TO1A 1MK7B 1ISNA 1NTYA 2UZSA 4L6EA 3GYOA 1X05A 1MPHA 3PVLA 1EGXA 3KRXA 1Q67A 3QIJA 5D3XA 5C5BA 2HTHB 2J0KA 1Z87A 4IFSA 2L1CA 2M14A 5J3QA 5JHHA 4YONA 4IOYX 2GCLA 3PVUA 1U5DA 2RSGA 2IFSA 2J59M 4DX8A 1TQZA 1B55A 4MT7A 5CLLB 1ZC4B 3P6AA 1WI1A 1V61A 4PQ0A 4A6FB 2J0MA 4K81A 1J0WA 5D3YA 2CY5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D0N B;  2K2U A;  4EKU A;  1UNR A;  2GJY A;  2YVC A;  5C6R A;  2QKL A;  2YRY A;  4C0A A;  2RNR B;  4HDQ A;  2RLO A;  1P3R A;  2DLW A;  1K5G B;  2DHJ A;  5LON B;  3HQC A;  1NTV A;  3KSY A;  2I1J A;  1V5M A;  2D11 A;  4CYE A;  4HHV A;  5GOW B;  1TXD A;  4H8S A;  1SGH A;  1FGY A;  1MAI A;  4HAW B;  3KZ1 A;  4HAV B;  4XWX A;  5JLJ B;  1UPQ A;  2NMB A;  1WVH A;  3SUZ A;  4KHO A;  1XR0 B;  3PG7 A;  1XX0 A;  4K2P A;  1FGZ A;  2DTC A;  3M1I B;  1EF1 A;  2I1K A;  1FAO A;  2Z0P A;  2Y8F A;  4GN1 A;  5C79 A;  1U5E A;  3ZDT A;  2X18 A;  3FSS A;  4KHB B;  1MIZ B;  2MFQ A;  1DDV A;  4A6H A;  4A6F A;  1M7E A;  4ZRK A;  3HK0 A;  3CXB B;  2LOX A;  4CHJ A;  2P0H A;  2DN6 A;  1ZM0 A;  1ZSQ A;  5JP4 A;  5L81 A;  2VSZ A;  2Y8G A;  2BCJ A;  5EFX A;  2YS1 A;  2ELA A;  4GZU A;  3FEH A;  2D9X A;  1N3H A;  2DHI A;  2P8V A;  5D27 A;  2MDX A;  2EMS A;  2K00 A;  1I7A A;  2KUP A;  4MK0 A;  3NSU A;  1X11 A;  3QBV B;  1KI1 B;  5DHF B;  2P0F A;  2COF A;  1ZC3 B;  2N23 A;  2KCJ A;  1V5P A;  3MPX A;  1H10 A;  1BAK A;  2CAY A;  2N0Y A;  2YS3 A;  2DX5 A;  3U8Z A;  1UEF A;  5CLQ B;  4EMO A;  3GYP A;  4Y94 A;  2YT1 A;  2RVB B;  2DKQ A;  2HE7 A;  3SYX A;  1XOD A;  5FI0 A;  2P0D A;  2ZPY A;  1WG7 A;  4NY0 A;  4B6H A;  4K17 A;  2DKP A;  3ML4 A;  3F5R A;  2L2I A;  3TW1 A;  1U2B A;  3A8P A;  1Y5O A;  2COA A;  1XKE A;  5D3W A;  2Z0Q A;  3PSC A;  3WYF B;  3AJ4 A;  3D8E A;  3D8D A;  3X23 A;  3ULB A;  1PFJ A;  2D9V A;  3U7D A;  2LYD A;  1KZG A;  5HE0 A;  5KQ4 A;  5J3Y A;  1UNQ A;  3BJI A;  2XQN M;  2Y7B A;  3F0W A;  1XD4 A;  2AEH A;  3PZD A;  2ROV A;  3QWM A;  3OAN A;  4Z2M B;  3DXC A;  1U5G A;  1M7R A;  1U29 A;  4GXB A;  2OTX A;  4HAY B;  2RGN B;  5DIF B;  1NU2 A;  1QQG A;  1LB1 A;  2Q13 A;  1BWN A;  2D9Y A;  4BBK A;  3DXE A;  2FJL A;  4WJ7 A;  3SNH A;  2GCJ A;  2LG1 A;  1WGU A;  1H4R A;  2Z0O A;  1PLS A;  1PMS A;  4HAZ B;  4HB2 B;  1SHC A;  1GC6 A;  1FHW A;  2D2Q A;  4KVG B;  1DBH A;  2CRF A;  1K5D B;  2R0D A;  2MWN B;  1GC7 A;  2YT0 A;  3VIA A;  2W2X D;  3TFM A;  1UNP A;  2KGX B;  1OY2 A;  4MY6 A;  1X1G A;  1I2H A;  1OQN A;  4TKN A;  2J0J A;  5C16 A;  2GS0 A;  1DDW A;  5JHG A;  1DRO A;  3FM8 C;  1MKE A;  4WVF B;  2D4Q A;  4IAP A;  2EC1 A;  2LUL A;  2YS5 A;  4HAX B;  4F7G A;  1WJM A;  4TYZ A;  2VRW B;  2JP2 A;  2DHK A;  4KAX B;  4KHA A;  4YL8 A;  2H7D A;  4GMV A;  1P5T A;  3KY9 A;  2NZ8 B;  1FB8 A;  4HB0 B;  2E2X A;  4EJN A;  3D8F A;  5FI1 A;  5D3V A;  3AU5 A;  5KQ1 A;  2VKI A;  3ODW A;  2R09 A;  1V89 A;  2EJ8 A;  5LOP B;  1FOE A;  3ODX A;  3BIN A;  1DDM A;  3PP2 A;  2PZ1 A;  2V76 A;  1RJ2 A;  2COC A;  3A98 B;  1MK9 B;  2D9Z A;  3UZT A;  1X1F A;  1AQC A;  2W2X C;  3DXD A;  4F7U P;  3TCA A;  1NI2 A;  1KZ7 A;  3ZVR A;  2ELB A;  2ROZ B;  2M38 A;  5DI9 B;  3V5W A;  1X86 A;  1AWE A;  4CHM A;  3SO6 A;  5DHA B;  4Z2N A;  3KRW A;  3RCP A;  1U27 A;  4ZRJ A;  5KCV A;  4HDO A;  2DX1 A;  3VOQ A;  2W2W A;  4K2O A;  3IVF A;  1W1G A;  4NSW A;  4PNK A;  2CY4 A;  1FHX A;  2G35 A;  3LJU X;  2YSZ A;  1P6S A;  4WSF A;  2H7E A;  1V5U A;  2MKR A;  1WJ1 A;  5HE1 A;  4HAT B;  2DYN A;  1Y19 B;  5HE3 A;  3G9W A;  1U5F A;  1W1H A;  3ODO A;  2K2J A;  4DX9 0;  1MIX A;  1DYN A;  3T06 A;  4HB4 B;  2I5C A;  1UPR A;  4HAU B;  2YF0 A;  3O96 A;  2QKM A;  1J19 A;  3AU4 A;  1QC6 A;  3WA0 A;  2LKO A;  1RRP B;  2IYB A;  4ZRI A;  5C5B B;  1TJ6 A;  2LOZ A;  3CIK A;  1E5W A;  1EVH A;  3TVV A;  2UZR A;  4F7H A;  3HW2 B;  4A5K A;  5DH9 B;  4DBB A;  2AL6 A;  1FHO A;  4GMX B;  4HB3 B;  1WGQ A;  3A8Q A;  2D10 A;  2D9W A;  4DXA B;  5HE2 A;  2DA0 A;  4GPT B;  2I5F A;  1IRS A;  1EAZ A;  2UVM A;  3PEG A;  3MDB C;  2EMT A;  1W1D A;  2DYQ A;  4P7I A;  2DFK A;  1OMW A;  1ZVR A;  3ULC A;  1GG3 A;  3SV1 A;  5J3T A;  1XCG A;  2ADZ A;  1LW3 A;  1BTN A;  3PVW A;  3P7Z A;  2COD A;  4A6K A;  3N7C A;  2RUK B;  1V88 A;  2OQB A;  1BTK A;  3TO1 A;  1MK7 B;  1ISN A;  1NTY A;  2UZS A;  4L6E A;  3GYO A;  1X05 A;  1MPH A;  3PVL A;  1EGX A;  3KRX A;  1Q67 A;  3QIJ A;  5D3X A;  5C5B A;  2HTH B;  2J0K A;  1Z87 A;  4IFS A;  2L1C A;  2M14 A;  5J3Q A;  5JHH A;  4YON A;  4IOY X;  2GCL A;  3PVU A;  1U5D A;  2RSG A;  2IFS A;  2J59 M;  4DX8 A;  1TQZ A;  1B55 A;  4MT7 A;  5CLL B;  1ZC4 B;  3P6A A;  1WI1 A;  1V61 A;  4PQ0 A;  4A6F B;  2J0M A;  4K81 A;  1J0W A;  5D3Y A;  2CY5 A; 
#chains in the Genus database with same CATH topology
 4D0N B;  2K2U A;  4DIX A;  4EKU A;  1UNR A;  2GJY A;  2YVC A;  5C6R A;  2QKL A;  2YRY A;  2Z4D A;  4C0A A;  2RNR B;  1T77 A;  3NW8 A;  4HDQ A;  2RLO A;  1P3R A;  2DLW A;  1K5G B;  2DHJ A;  5LON B;  3HQC A;  1NTV A;  3KSY A;  2I1J A;  1V5M A;  2D11 A;  4CYE A;  4HHV A;  5GOW B;  2K49 A;  1TXD A;  3NWA A;  4GNK B;  4H8S A;  1SGH A;  1FGY A;  1MAI A;  4HAW B;  3KZ1 A;  4HAV B;  4XWX A;  5JLJ B;  1UPQ A;  2NMB A;  1WVH A;  3SUZ A;  4KHO A;  1XR0 B;  5I2S A;  3PG7 A;  1XX0 A;  4K2P A;  1FGZ A;  2DTC A;  3M1I B;  1EF1 A;  2I1K A;  1FAO A;  2Z0P A;  2Y8F A;  4GN1 A;  5C79 A;  1U5E A;  3ZDT A;  2X18 A;  3FSS A;  4KHB B;  1MIZ B;  2MFQ A;  1DDV A;  4A6H A;  4A6F A;  1M7E A;  4ZRK A;  3HK0 A;  3CXB B;  2LOX A;  4CHJ A;  2P0H A;  2DN6 A;  1ZM0 A;  1ZSQ A;  5JP4 A;  5L81 A;  2VSZ A;  2Y8G A;  2BCJ A;  5EFX A;  2YS1 A;  2ELA A;  4GZU A;  3FEH A;  2D9X A;  1N3H A;  3A58 A;  2DHI A;  2P8V A;  5D27 A;  2MDX A;  2EMS A;  2K00 A;  1I7A A;  2KUP A;  4MK0 A;  4KHB A;  3NSU A;  2NBV A;  1X11 A;  3QBV B;  4QJ3 B;  1KI1 B;  5DHF B;  2P0F A;  2COF A;  1ZC3 B;  2N23 A;  4QJ5 B;  2KCJ A;  1V5P A;  3MPX A;  1H10 A;  1BAK A;  2CAY A;  2N0Y A;  2YS3 A;  2DX5 A;  3U8Z A;  1UEF A;  5CLQ B;  4EMO A;  3GYP A;  3U12 A;  4Y94 A;  2YT1 A;  2RVB B;  2DKQ A;  3B77 A;  2HE7 A;  3NWF A;  3SYX A;  1XOD A;  5FI0 A;  2P0D A;  2ZPY A;  1WG7 A;  4QXA B;  4NY0 A;  4B6H A;  4K17 A;  2DKP A;  3ML4 A;  3F5R A;  2L2I A;  3TW1 A;  1U2B A;  3A8P A;  1Y5O A;  2COA A;  1XKE A;  5D3W A;  2Z0Q A;  3PSC A;  5I2M A;  3WYF B;  3AJ4 A;  4OSN A;  3D8E A;  3D8D A;  3X23 A;  3ULB A;  1PFJ A;  2D9V A;  3U7D A;  2LYD A;  1KZG A;  5HE0 A;  5KQ4 A;  5J3Y A;  1UNQ A;  3BJI A;  2XQN M;  2Y7B A;  3F0W A;  1XD4 A;  2AEH A;  3PZD A;  2ROV A;  3QWM A;  2GUM A;  3OAN A;  4Z2M B;  3DXC A;  1U5G A;  1M7R A;  1U29 A;  4GXB A;  2OTX A;  4HAY B;  2RGN B;  5DIF B;  1NU2 A;  1QQG A;  1LB1 A;  2Q13 A;  1BWN A;  2D9Y A;  4BBK A;  3DXE A;  2FJL A;  4WJ7 A;  3SNH A;  2GCJ A;  2LG1 A;  1WGU A;  1H4R A;  2Z0O A;  1PLS A;  1PMS A;  4HAZ B;  4HB2 B;  4QJ4 B;  1SHC A;  1GC6 A;  1FHW A;  2D2Q A;  4KVG B;  1DBH A;  2CRF A;  1K5D B;  2R0D A;  2MWN B;  1GC7 A;  2YT0 A;  3VIA A;  2W2X D;  3TFM A;  1UNP A;  2KGX B;  1OY2 A;  4MY6 A;  1X1G A;  1I2H A;  1OQN A;  4TKN A;  2J0J A;  5C16 A;  2GS0 A;  1DDW A;  5JHG A;  1DRO A;  3FM8 C;  1MKE A;  4WVF B;  2D4Q A;  2ZKM X;  4IAP A;  2EC1 A;  2LUL A;  2YS5 A;  4HAX B;  4F7G A;  1WJM A;  4TYZ A;  2RRF A;  2VRW B;  2JP2 A;  2DHK A;  4KAX B;  4KHA A;  4YL8 A;  2H7D A;  4GMV A;  1P5T A;  2FJU B;  3KY9 A;  2NZ8 B;  1FB8 A;  4HB0 B;  2E2X A;  4EJN A;  3D8F A;  5FI1 A;  5D3V A;  3AU5 A;  5KQ1 A;  2VKI A;  3ODW A;  2R09 A;  1V89 A;  2EJ8 A;  3HSA A;  5LOP B;  1FOE A;  2YT2 A;  3ODX A;  3BIN A;  1DDM A;  3PP2 A;  2PZ1 A;  2V76 A;  1RJ2 A;  2COC A;  3A98 B;  1MK9 B;  2D9Z A;  3UZT A;  1X1F A;  1AQC A;  3HIE A;  2W2X C;  3DXD A;  4F7U P;  2KR0 A;  3TCA A;  1NI2 A;  1KZ7 A;  3ZVR A;  3OHM B;  2ELB A;  2ROZ B;  2M38 A;  5DI9 B;  3V5W A;  1X86 A;  1AWE A;  4CHM A;  3SO6 A;  5DHA B;  4Z2N A;  3KRW A;  3RCP A;  1U27 A;  4ZRJ A;  5KCV A;  4HDO A;  2DX1 A;  4L1R A;  3VOQ A;  2W2W A;  4K2O A;  3IVF A;  1W1G A;  4NSW A;  4PNK A;  2CY4 A;  3DCX A;  1FHX A;  2G35 A;  3LJU X;  2YSZ A;  1P6S A;  4WSF A;  2H7E A;  1V5U A;  2MKR A;  1WJ1 A;  4CSQ A;  5HE1 A;  2DYN A;  1Y19 B;  4HAT B;  5HE3 A;  3G9W A;  1U5F A;  1W1H A;  3ODO A;  2K2J A;  4DX9 0;  1MIX A;  1DYN A;  3T06 A;  4HB4 B;  2I5C A;  1UPR A;  4HAU B;  2YF0 A;  3O96 A;  2KIE A;  2QKM A;  1J19 A;  3AU4 A;  1QC6 A;  3WA0 A;  2LKO A;  1RRP B;  2IYB A;  4GOU A;  5IRS A;  4ZRI A;  5C5B B;  1TJ6 A;  3FVC A;  1MI1 A;  2LOZ A;  3CIK A;  1E5W A;  1EVH A;  4OT1 A;  2UZR A;  3TVV A;  4F7H A;  3HW2 B;  4A5K A;  5DH9 B;  4DBB A;  2AL6 A;  1FHO A;  4GMX B;  4HB3 B;  1WGQ A;  3A8Q A;  2D10 A;  2D9W A;  4DXA B;  4D6W A;  5HE2 A;  2DA0 A;  4GPT B;  2I5F A;  1IRS A;  1EAZ A;  2UVM A;  3PEG A;  5M4Y B;  3MDB C;  2EMT A;  1W1D A;  1ZYI A;  2DYQ A;  2DFK A;  1OMW A;  1ZVR A;  4P7I A;  3ULC A;  4HSI A;  1GG3 A;  3SV1 A;  2K8E A;  5J3T A;  1XCG A;  2ADZ A;  1LW3 A;  1BTN A;  3PVW A;  3P7Z A;  2COD A;  4A6K A;  3N7C A;  2RUK B;  1V88 A;  2OQB A;  1BTK A;  3TO1 A;  1MK7 B;  2KIG A;  1ISN A;  1NTY A;  2UZS A;  4L6E A;  3GYO A;  1X05 A;  1MPH A;  3PVL A;  1EGX A;  3KRX A;  1Q67 A;  3QIJ A;  5D3X A;  3NWD A;  5C5B A;  2HTH B;  2J0K A;  1Z87 A;  4IFS A;  2Z59 A;  2L1C A;  2M14 A;  5LG4 B;  2R2Y A;  5J3Q A;  5JHH A;  4YON A;  2GCL A;  4IOY X;  3PVU A;  1U5D A;  2RSG A;  2IFS A;  2J59 M;  4DX8 A;  1TQZ A;  2Z13 A;  1B55 A;  4MT7 A;  5CLL B;  1ZC4 B;  3P6A A;  1WI1 A;  1V61 A;  2KUQ A;  4PQ0 A;  4A6F B;  2J0M A;  4K81 A;  1J0W A;  2Z14 A;  5D3Y A;  2CY5 A; 
#chains in the Genus database with same CATH homology
 4D0N B;  2K2U A;  4EKU A;  1UNR A;  2GJY A;  2YVC A;  5C6R A;  2QKL A;  2YRY A;  4C0A A;  2RNR B;  4HDQ A;  2RLO A;  1P3R A;  2DLW A;  1K5G B;  2DHJ A;  5LON B;  3HQC A;  1NTV A;  3KSY A;  2I1J A;  1V5M A;  2D11 A;  4CYE A;  4HHV A;  5GOW B;  1TXD A;  4H8S A;  1SGH A;  1FGY A;  1MAI A;  4HAW B;  3KZ1 A;  4HAV B;  4XWX A;  5JLJ B;  1UPQ A;  2NMB A;  1WVH A;  3SUZ A;  4KHO A;  1XR0 B;  3PG7 A;  1XX0 A;  4K2P A;  1FGZ A;  2DTC A;  3M1I B;  1EF1 A;  2I1K A;  1FAO A;  2Z0P A;  2Y8F A;  4GN1 A;  5C79 A;  1U5E A;  3ZDT A;  2X18 A;  3FSS A;  4KHB B;  1MIZ B;  2MFQ A;  1DDV A;  4A6H A;  4A6F A;  1M7E A;  4ZRK A;  3HK0 A;  3CXB B;  2LOX A;  4CHJ A;  2P0H A;  2DN6 A;  1ZM0 A;  1ZSQ A;  5JP4 A;  5L81 A;  2VSZ A;  2Y8G A;  2BCJ A;  5EFX A;  2YS1 A;  2ELA A;  4GZU A;  3FEH A;  2D9X A;  1N3H A;  2DHI A;  2P8V A;  5D27 A;  2MDX A;  2EMS A;  2K00 A;  1I7A A;  2KUP A;  4MK0 A;  3NSU A;  1X11 A;  3QBV B;  1KI1 B;  5DHF B;  2P0F A;  2COF A;  1ZC3 B;  2N23 A;  2KCJ A;  1V5P A;  3MPX A;  1H10 A;  1BAK A;  2CAY A;  2N0Y A;  2YS3 A;  2DX5 A;  3U8Z A;  1UEF A;  5CLQ B;  4EMO A;  3GYP A;  4Y94 A;  2YT1 A;  2RVB B;  2DKQ A;  2HE7 A;  3SYX A;  1XOD A;  5FI0 A;  2P0D A;  2ZPY A;  1WG7 A;  4NY0 A;  4B6H A;  4K17 A;  2DKP A;  3ML4 A;  3F5R A;  2L2I A;  3TW1 A;  1U2B A;  3A8P A;  1Y5O A;  2COA A;  1XKE A;  5D3W A;  2Z0Q A;  3PSC A;  3WYF B;  3AJ4 A;  3D8E A;  3D8D A;  3X23 A;  3ULB A;  1PFJ A;  2D9V A;  3U7D A;  2LYD A;  1KZG A;  5HE0 A;  5KQ4 A;  5J3Y A;  1UNQ A;  3BJI A;  2XQN M;  2Y7B A;  3F0W A;  1XD4 A;  2AEH A;  3PZD A;  2ROV A;  3QWM A;  3OAN A;  4Z2M B;  3DXC A;  1U5G A;  1M7R A;  1U29 A;  4GXB A;  2OTX A;  4HAY B;  2RGN B;  5DIF B;  1NU2 A;  1QQG A;  1LB1 A;  2Q13 A;  1BWN A;  2D9Y A;  4BBK A;  3DXE A;  2FJL A;  4WJ7 A;  3SNH A;  2GCJ A;  2LG1 A;  1WGU A;  1H4R A;  2Z0O A;  1PLS A;  1PMS A;  4HAZ B;  4HB2 B;  1SHC A;  1GC6 A;  1FHW A;  2D2Q A;  4KVG B;  1DBH A;  2CRF A;  1K5D B;  2R0D A;  2MWN B;  1GC7 A;  2YT0 A;  3VIA A;  2W2X D;  3TFM A;  1UNP A;  2KGX B;  1OY2 A;  4MY6 A;  1X1G A;  1I2H A;  1OQN A;  4TKN A;  2J0J A;  5C16 A;  2GS0 A;  1DDW A;  5JHG A;  1DRO A;  3FM8 C;  1MKE A;  4WVF B;  2D4Q A;  4IAP A;  2EC1 A;  2LUL A;  2YS5 A;  4HAX B;  4F7G A;  1WJM A;  4TYZ A;  2VRW B;  2JP2 A;  2DHK A;  4KAX B;  4KHA A;  4YL8 A;  2H7D A;  4GMV A;  1P5T A;  3KY9 A;  2NZ8 B;  1FB8 A;  4HB0 B;  2E2X A;  4EJN A;  3D8F A;  5FI1 A;  5D3V A;  3AU5 A;  5KQ1 A;  2VKI A;  3ODW A;  2R09 A;  1V89 A;  2EJ8 A;  5LOP B;  1FOE A;  3ODX A;  3BIN A;  1DDM A;  3PP2 A;  2PZ1 A;  2V76 A;  1RJ2 A;  2COC A;  3A98 B;  1MK9 B;  2D9Z A;  3UZT A;  1X1F A;  1AQC A;  2W2X C;  3DXD A;  4F7U P;  3TCA A;  1NI2 A;  1KZ7 A;  3ZVR A;  2ELB A;  2ROZ B;  2M38 A;  5DI9 B;  3V5W A;  1X86 A;  1AWE A;  4CHM A;  3SO6 A;  5DHA B;  4Z2N A;  3KRW A;  3RCP A;  1U27 A;  4ZRJ A;  5KCV A;  4HDO A;  2DX1 A;  3VOQ A;  2W2W A;  4K2O A;  3IVF A;  1W1G A;  4NSW A;  4PNK A;  2CY4 A;  1FHX A;  2G35 A;  3LJU X;  2YSZ A;  1P6S A;  4WSF A;  2H7E A;  1V5U A;  2MKR A;  1WJ1 A;  5HE1 A;  4HAT B;  2DYN A;  1Y19 B;  5HE3 A;  3G9W A;  1U5F A;  1W1H A;  3ODO A;  2K2J A;  4DX9 0;  1MIX A;  1DYN A;  3T06 A;  4HB4 B;  2I5C A;  1UPR A;  4HAU B;  2YF0 A;  3O96 A;  2QKM A;  1J19 A;  3AU4 A;  1QC6 A;  3WA0 A;  2LKO A;  1RRP B;  2IYB A;  4ZRI A;  5C5B B;  1TJ6 A;  2LOZ A;  3CIK A;  1E5W A;  1EVH A;  3TVV A;  2UZR A;  4F7H A;  3HW2 B;  4A5K A;  5DH9 B;  4DBB A;  2AL6 A;  1FHO A;  4GMX B;  4HB3 B;  1WGQ A;  3A8Q A;  2D10 A;  2D9W A;  4DXA B;  5HE2 A;  2DA0 A;  4GPT B;  2I5F A;  1IRS A;  1EAZ A;  2UVM A;  3PEG A;  3MDB C;  2EMT A;  1W1D A;  2DYQ A;  4P7I A;  2DFK A;  1OMW A;  1ZVR A;  3ULC A;  1GG3 A;  3SV1 A;  5J3T A;  1XCG A;  2ADZ A;  1LW3 A;  1BTN A;  3PVW A;  3P7Z A;  2COD A;  4A6K A;  3N7C A;  2RUK B;  1V88 A;  2OQB A;  1BTK A;  3TO1 A;  1MK7 B;  1ISN A;  1NTY A;  2UZS A;  4L6E A;  3GYO A;  1X05 A;  1MPH A;  3PVL A;  1EGX A;  3KRX A;  1Q67 A;  3QIJ A;  5D3X A;  5C5B A;  2HTH B;  2J0K A;  1Z87 A;  4IFS A;  2L1C A;  2M14 A;  5J3Q A;  5JHH A;  4YON A;  4IOY X;  2GCL A;  3PVU A;  1U5D A;  2RSG A;  2IFS A;  2J59 M;  4DX8 A;  1TQZ A;  1B55 A;  4MT7 A;  5CLL B;  1ZC4 B;  3P6A A;  1WI1 A;  1V61 A;  4PQ0 A;  4A6F B;  2J0M A;  4K81 A;  1J0W A;  5D3Y A;  2CY5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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