1UNQA

High resolution crystal structure of the pleckstrin homology domain of protein kinase b/akt bound to ins(1,3,4,5)-tetrakisphophate
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
117
structure length
117
Chain Sequence
SMSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords RAC-ALPHA SERINE/THREONINE KINASE
publication title Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 32
structure length 117
sequence length 117
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2003-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1unqA00
1TXDA 1FGYA 2J0MA 4HATB 1U27A 2QKMA 5HE0A 5C6RA 2EMTA 2YRYA 3OANA 1UNPA 2N23A 5C16A 1E5WA 4PQ0A 2EC1A 2W2XD 1I7AA 2X18A 2MWNB 1AWEA 3PEGA 1ZM0A 5HE1A 2D2QA 4GZUA 1X86A 1SGHA 1J0WA 2W2XC 2MKRA 2NMBA 2D10A 2DN6A 3GYPA 2H7EA 2CAYA 2R09A 2KUPA 2DLWA 1X11A 5JP4A 3CIKA 1V89A 1PLSA 2YS5A 1X1GA 1V88A 2RLOA 1PMSA 3TW1A 1Y5OA 2DA0A 4A6KA 1NTYA 2YT0A 3RCPA 3QWMA 2DHJA 1XR0B 4PNKA 3P6AA 1OQNA 3U8ZA 2ROZB 1ISNA 1K5DB 1MK9B 1U5DA 2VSZA 4L6EA 2DX1A 5KQ4A 2AL6A 1UNQA 1FOEA 1BWNA 1DBHA 2OQBA 1P5TA 2GCJA 1RJ2A 3ODOA 3AJ4A 2GCLA 4K17A 1WJ1A 5DHAB 3MPXA 1MIXA 2L2IA 4WJ7A 4YONA 1KZGA 5J3YA 5DIFB 3TVVA 1M7RA 2D9XA 4IOYX 5L81A 1XODA 2CY5A 3BINA 4KHOA 4KVGB 5D27A 5JLJB 5LOPB 2FJLA 2DKQA 2P0FA 1WVHA 1U29A 3PVLA 1KZ7A 2YS1A 4WVFB 2Z0QA 1X05A 5GOWB 2LULA 1WGQA 4GXBA 4NY0A 1ZVRA 3TCAA 1EVHA 2HE7A 1UEFA 4D0NB 4F7UP 2DTCA 4HHVA 2G35A 3A98B 2AEHA 1LB1A 1V61A 3M1IB 4A5KA 1DYNA 1V5PA 3DXDA 2D9WA 3KRXA 2DHIA 5EFXA 2L1CA 4C0AA 1K5GB 3V5WA 3FM8C 4DX90 3SYXA 1U5GA 3F0WA 4GN1A 4WSFA 2V76A 5CLQB 4A6FB 3FEHA 4EKUA 2JP2A 2P8VA 5FI1A 4EJNA 3D8DA 3PP2A 4A6FA 1I2HA 4HB2B 2COAA 5C5BA 4CYEA 2LOZA 4HB4B 2HTHB 4H8SA 2K2UA 1U2BA 1MIZB 4KAXB 1PFJA 3ODXA 1P6SA 2I5CA 1WGUA 5D3VA 1N3HA 3TFMA 4CHMA 1AQCA 1B55A 4A6HA 3KRWA 2ELBA 4HAWB 4CHJA 1J19A 4HAZB 2ROVA 2RUKB 1QQGA 4K2PA 3AU5A 3D8FA 2LG1A 3IVFA 1RRPB 4B6HA 2M38A 2E2XA 3SUZA 2H7DA 2MFQA 3HQCA 3SNHA 2YF0A 3HW2B 2CODA 3SO6A 1P3RA 2DX5A 5KQ1A 1EGXA 2PZ1A 4DX8A 1M7EA 2Y7BA 4HAVB 1FHWA 2GJYA 2J0KA 2KGXB 3ODWA 4ZRKA 1XD4A 4IAPA 3P7ZA 1UPRA 1DDWA 3N7CA 1W1HA 4TKNA 3TO1A 3PG7A 3ULCA 1GG3A 2IFSA 4P7IA 1OMWA 1ZSQA 5DH9B 3DXCA 2Z0OA 2EMSA 1MAIA 4HB3B 4EMOA 3GYOA 2GS0A 3PVUA 4NSWA 1DDVA 1BTNA 1SHCA 1EAZA 5FI0A 2RNRB 2YT1A 4HDQA 2D9YA 1TJ6A 2D9ZA 1FAOA 4HAYB 1WI1A 1KI1B 2Y8FA 2J59M 5JHHA 1Y19B 1Z87A 4YL8A 5JHGA 4MK0A 2NZ8B 2D9VA 2EJ8A 1X1FA 2XQNM 2MDXA 3LJUX 4KHAA 3WA0A 2D4QA 2J0JA 3CXBB 3PVWA 2RSGA 2LOXA 3X23A 1DROA 1IRSA 4ZRIA 2M14A 5LONB 1WJMA 3DXEA 3ZVRA 1MKEA 5HE2A 4DBBA 4K2OA 2R0DA 3D8EA 2W2WA 2VKIA 1Q67A 3MDBC 3A8PA 2UZRA 5J3TA 1V5MA 1NTVA 1UPQA 2K00A 3UZTA 3U7DA 1V5UA 1MK7B 3G9WA 5J3QA 3FSSA 5C5BB 1XCGA 1FHXA 4MY6A 1TQZA 3BJIA 1W1GA 4GPTB 3VOQA 1NI2A 3ZDTA 1FHOA 1UNRA 2VRWB 4HB0B 3NSUA 1GC7A 4TYZA 3F5RA 2KCJA 2OTXA 5C79A 2UZSA 4ZRJA 3ULBA 2Q13A 1BAKA 1U5EA 3QBVB 1H4RA 1OY2A 2IYBA 1W1DA 4DXAB 1XX0A 2I5FA 4F7GA 4GMXB 2D11A 2RGNB 2DHKA 2DYNA 3PSCA 2COFA 1H10A 1FGZA 2BCJA 2P0HA 4GMVA 5DHFB 1ZC3B 5D3YA 4Z2NA 3ML4A 1GC6A 2P0DA 2DYQA 2YS3A 1QC6A 1ZC4B 1U5FA 2DFKA 5D3WA 4F7HA 2CRFA 2LYDA 2I1JA 2ELAA 2K2JA 2QKLA 2ZPYA 3SV1A 1EF1A 3HK0A 2N0YA 3T06A 5CLLB 3O96A 2Y8GA 4HDOA 4XWXA 2I1KA 3AU4A 1NU2A 1MPHA 1WG7A 4HAXB 5DI9B 3WYFB 2COCA 4MT7A 4HAUB 4Z2MB 2ADZA 5HE3A 3KY9A 1LW3A 1FB8A 2YVCA 1BTKA 4KHBB 3QIJA 4Y94A 1XKEA 4IFSA 2YSZA 2Z0PA 5KCVA 3KSYA 3A8QA 4K81A 5D3XA 3VIAA 2UVMA 3KZ1A 2RVBB 2LKOA 3PZDA 2CY4A 4BBKA 2DKPA 1DDMA
chains in the Genus database with same CATH superfamily
1TXDA 1FGYA 2J0MA 4HATB 1U27A 2QKMA 5HE0A 5C6RA 2EMTA 2YRYA 3HSAA 3OANA 1UNPA 4GNKB 2N23A 5C16A 1E5WA 4PQ0A 2EC1A 2YT2A 2W2XD 1I7AA 2X18A 2MWNB 1AWEA 3PEGA 1ZM0A 5HE1A 2D2QA 5LG4B 4GZUA 1X86A 1SGHA 4QJ5B 1J0WA 2W2XC 2MKRA 2NMBA 2D10A 2DN6A 3GYPA 2H7EA 2CAYA 2R09A 2KUPA 3NWFA 2DLWA 1X11A 5JP4A 3CIKA 1V89A 1PLSA 2YS5A 1X1GA 1V88A 2RLOA 1PMSA 3TW1A 1Y5OA 2DA0A 4A6KA 5I2MA 1NTYA 2YT0A 3RCPA 3QWMA 2DHJA 1XR0B 4PNKA 3P6AA 1OQNA 3U8ZA 2ROZB 1ISNA 1K5DB 1MK9B 1U5DA 2VSZA 4L6EA 2DX1A 5KQ4A 2AL6A 1UNQA 1FOEA 1BWNA 1DBHA 2OQBA 1P5TA 2GCJA 1RJ2A 2RRFA 2Z14A 3ODOA 3AJ4A 2GCLA 4K17A 1WJ1A 5DHAB 3MPXA 1MIXA 2L2IA 4WJ7A 4YONA 1KZGA 5J3YA 5DIFB 3TVVA 1M7RA 2D9XA 4IOYX 5L81A 1XODA 2CY5A 3BINA 4KHOA 4KVGB 5D27A 5JLJB 5LOPB 2FJLA 2DKQA 2P0FA 1WVHA 1U29A 1KZ7A 3PVLA 2YS1A 4WVFB 3OHMB 2Z0QA 1X05A 5GOWB 2LULA 1WGQA 4GXBA 4NY0A 1ZVRA 3TCAA 1EVHA 2HE7A 1UEFA 3NWAA 4D0NB 4F7UP 2DTCA 4HHVA 3NWDA 2G35A 3A98B 4OSNA 2AEHA 1LB1A 1V61A 3M1IB 4A5KA 1DYNA 1V5PA 3DXDA 2D9WA 3KRXA 2DHIA 5EFXA 2L1CA 4C0AA 1K5GB 3V5WA 3FM8C 4DX90 3SYXA 1U5GA 3F0WA 4GN1A 4WSFA 4HSIA 2V76A 5CLQB 4A6FB 3FEHA 4EKUA 2JP2A 2R2YA 2P8VA 5FI1A 4EJNA 2KIGA 3D8DA 3PP2A 4A6FA 1I2HA 4HB2B 2Z4DA 4QJ3B 2COAA 3U12A 5C5BA 4CYEA 2LOZA 4HB4B 2HTHB 4H8SA 2K2UA 1U2BA 1MIZB 4KAXB 1PFJA 3ODXA 1P6SA 2I5CA 1WGUA 5D3VA 1N3HA 3TFMA 4CHMA 1AQCA 1B55A 4A6HA 3KRWA 1MI1A 3FVCA 2ELBA 4L1RA 4HAWB 4CHJA 1J19A 4HAZB 5M4YB 2ROVA 2RUKB 2KUQA 1QQGA 4K2PA 3AU5A 3D8FA 2LG1A 3IVFA 1RRPB 4B6HA 2M38A 2E2XA 3SUZA 2H7DA 2MFQA 3HQCA 3SNHA 2YF0A 3HW2B 3DCXA 2CODA 3SO6A 1P3RA 2DX5A 5KQ1A 1EGXA 2PZ1A 4DX8A 1M7EA 2Y7BA 4HAVB 4QJ4B 1FHWA 2GJYA 2J0KA 2KGXB 3ODWA 4ZRKA 1XD4A 4IAPA 3P7ZA 1UPRA 1DDWA 3N7CA 1W1HA 4TKNA 3TO1A 3PG7A 3ULCA 1GG3A 2IFSA 4P7IA 1OMWA 1ZSQA 5DH9B 3DXCA 2Z0OA 2EMSA 4D6WA 1MAIA 2K8EA 4HB3B 4EMOA 3GYOA 2GS0A 3PVUA 4NSWA 3NW8A 1DDVA 1BTNA 1SHCA 1EAZA 5FI0A 2RNRB 2YT1A 4HDQA 2D9YA 1TJ6A 2D9ZA 1FAOA 4HAYB 1WI1A 1ZYIA 1KI1B 2Y8FA 2J59M 5JHHA 1Y19B 1Z87A 4YL8A 5JHGA 4MK0A 2NZ8B 2D9VA 2EJ8A 1X1FA 2XQNM 2MDXA 3LJUX 4KHAA 3WA0A 2D4QA 2J0JA 3CXBB 3PVWA 2RSGA 2LOXA 3X23A 1DROA 1IRSA 4ZRIA 2M14A 5LONB 2ZKMX 1WJMA 5IRSA 3DXEA 3ZVRA 4KHBA 1MKEA 5HE2A 4DBBA 4K2OA 2R0DA 3D8EA 2W2WA 2VKIA 1Q67A 3MDBC 3A8PA 2UZRA 5J3TA 1V5MA 1NTVA 1UPQA 2K00A 5I2SA 3UZTA 3U7DA 1V5UA 1MK7B 3B77A 4GOUA 3G9WA 5J3QA 3FSSA 5C5BB 3HIEA 1XCGA 1FHXA 4MY6A 1TQZA 3BJIA 1W1GA 4GPTB 3VOQA 1NI2A 3ZDTA 1FHOA 1UNRA 2VRWB 4HB0B 3NSUA 1GC7A 4TYZA 3F5RA 2GUMA 2KCJA 2OTXA 5C79A 2UZSA 4ZRJA 3ULBA 2Q13A 4DIXA 1BAKA 1U5EA 3QBVB 1H4RA 1OY2A 2IYBA 1W1DA 4DXAB 1XX0A 2I5FA 4F7GA 4GMXB 2D11A 2RGNB 2DHKA 2DYNA 3PSCA 2COFA 2Z59A 1H10A 1FGZA 2BCJA 2K49A 2P0HA 4GMVA 5DHFB 2NBVA 1ZC3B 5D3YA 4Z2NA 4CSQA 3ML4A 1GC6A 2P0DA 2DYQA 3A58A 2YS3A 2FJUB 1QC6A 1ZC4B 1U5FA 2DFKA 5D3WA 4F7HA 2KIEA 2CRFA 2LYDA 2I1JA 1T77A 2ELAA 2K2JA 2QKLA 2ZPYA 4QXAB 1EF1A 3SV1A 3HK0A 2N0YA 3T06A 5CLLB 3O96A 2Y8GA 4HDOA 4XWXA 2I1KA 3AU4A 1NU2A 1MPHA 1WG7A 4HAXB 5DI9B 3WYFB 2COCA 4MT7A 4HAUB 4Z2MB 2ADZA 2KR0A 5HE3A 3KY9A 1LW3A 1FB8A 2YVCA 1BTKA 4KHBB 3QIJA 4Y94A 1XKEA 4IFSA 4OT1A 2YSZA 2Z0PA 5KCVA 3KSYA 3A8QA 4K81A 5D3XA 3VIAA 2UVMA 3KZ1A 2RVBB 2Z13A 2LKOA 3PZDA 2CY4A 4BBKA 2DKPA 1DDMA
chains in the Genus database with same CATH topology
1TXDA 1FGYA 2J0MA 4HATB 1U27A 2QKMA 5HE0A 5C6RA 2EMTA 2YRYA 3OANA 1UNPA 2N23A 5C16A 1E5WA 4PQ0A 2EC1A 2W2XD 1I7AA 2X18A 2MWNB 1AWEA 3PEGA 1ZM0A 5HE1A 2D2QA 4GZUA 1X86A 1SGHA 1J0WA 2W2XC 2MKRA 2NMBA 2D10A 2DN6A 3GYPA 2H7EA 2CAYA 2R09A 2KUPA 2DLWA 1X11A 5JP4A 3CIKA 1V89A 1PLSA 2YS5A 1X1GA 1V88A 2RLOA 1PMSA 3TW1A 1Y5OA 2DA0A 4A6KA 1NTYA 2YT0A 3RCPA 3QWMA 2DHJA 1XR0B 4PNKA 3P6AA 1OQNA 3U8ZA 2ROZB 1ISNA 1K5DB 1MK9B 1U5DA 2VSZA 4L6EA 2DX1A 5KQ4A 2AL6A 1UNQA 1FOEA 1BWNA 1DBHA 2OQBA 1P5TA 2GCJA 1RJ2A 3ODOA 3AJ4A 2GCLA 4K17A 1WJ1A 5DHAB 3MPXA 1MIXA 2L2IA 4WJ7A 4YONA 1KZGA 5J3YA 5DIFB 3TVVA 1M7RA 2D9XA 4IOYX 5L81A 1XODA 2CY5A 3BINA 4KHOA 4KVGB 5D27A 5JLJB 5LOPB 2FJLA 2DKQA 2P0FA 1WVHA 1U29A 3PVLA 1KZ7A 2YS1A 4WVFB 2Z0QA 1X05A 5GOWB 2LULA 1WGQA 4GXBA 4NY0A 1ZVRA 3TCAA 1EVHA 2HE7A 1UEFA 4D0NB 4F7UP 2DTCA 4HHVA 2G35A 3A98B 2AEHA 1LB1A 1V61A 3M1IB 4A5KA 1DYNA 1V5PA 3DXDA 2D9WA 3KRXA 2DHIA 5EFXA 2L1CA 4C0AA 1K5GB 3V5WA 3FM8C 4DX90 3SYXA 1U5GA 3F0WA 4GN1A 4WSFA 2V76A 5CLQB 4A6FB 3FEHA 4EKUA 2JP2A 2P8VA 5FI1A 4EJNA 3D8DA 3PP2A 4A6FA 1I2HA 4HB2B 2COAA 5C5BA 4CYEA 2LOZA 4HB4B 2HTHB 4H8SA 2K2UA 1U2BA 1MIZB 4KAXB 1PFJA 3ODXA 1P6SA 2I5CA 1WGUA 5D3VA 1N3HA 3TFMA 4CHMA 1AQCA 1B55A 4A6HA 3KRWA 2ELBA 4HAWB 4CHJA 1J19A 4HAZB 2ROVA 2RUKB 1QQGA 4K2PA 3AU5A 3D8FA 2LG1A 3IVFA 1RRPB 4B6HA 2M38A 2E2XA 3SUZA 2H7DA 2MFQA 3HQCA 3SNHA 2YF0A 3HW2B 2CODA 3SO6A 1P3RA 2DX5A 5KQ1A 1EGXA 2PZ1A 4DX8A 1M7EA 2Y7BA 4HAVB 1FHWA 2GJYA 2J0KA 2KGXB 3ODWA 4ZRKA 1XD4A 4IAPA 3P7ZA 1UPRA 1DDWA 3N7CA 1W1HA 4TKNA 3TO1A 3PG7A 3ULCA 1GG3A 2IFSA 4P7IA 1OMWA 1ZSQA 5DH9B 3DXCA 2Z0OA 2EMSA 1MAIA 4HB3B 4EMOA 3GYOA 2GS0A 3PVUA 4NSWA 1DDVA 1BTNA 1SHCA 1EAZA 5FI0A 2RNRB 2YT1A 4HDQA 2D9YA 1TJ6A 2D9ZA 1FAOA 4HAYB 1WI1A 1KI1B 2Y8FA 2J59M 5JHHA 1Y19B 1Z87A 4YL8A 5JHGA 4MK0A 2NZ8B 2D9VA 2EJ8A 1X1FA 2XQNM 2MDXA 3LJUX 4KHAA 3WA0A 2D4QA 2J0JA 3CXBB 3PVWA 2RSGA 2LOXA 3X23A 1DROA 1IRSA 4ZRIA 2M14A 5LONB 1WJMA 3DXEA 3ZVRA 1MKEA 5HE2A 4DBBA 4K2OA 2R0DA 3D8EA 2W2WA 2VKIA 1Q67A 3MDBC 3A8PA 2UZRA 5J3TA 1V5MA 1NTVA 1UPQA 2K00A 3UZTA 3U7DA 1V5UA 1MK7B 3G9WA 5J3QA 3FSSA 5C5BB 1XCGA 1FHXA 4MY6A 1TQZA 3BJIA 1W1GA 4GPTB 3VOQA 1NI2A 3ZDTA 1FHOA 1UNRA 2VRWB 4HB0B 3NSUA 1GC7A 4TYZA 3F5RA 2KCJA 2OTXA 5C79A 2UZSA 4ZRJA 3ULBA 2Q13A 1BAKA 1U5EA 3QBVB 1H4RA 1OY2A 2IYBA 1W1DA 4DXAB 1XX0A 2I5FA 4F7GA 4GMXB 2D11A 2RGNB 2DHKA 2DYNA 3PSCA 2COFA 1H10A 1FGZA 2BCJA 2P0HA 4GMVA 5DHFB 1ZC3B 5D3YA 4Z2NA 3ML4A 1GC6A 2P0DA 2DYQA 2YS3A 1QC6A 1ZC4B 1U5FA 2DFKA 5D3WA 4F7HA 2CRFA 2LYDA 2I1JA 2ELAA 2K2JA 2QKLA 2ZPYA 3SV1A 1EF1A 3HK0A 2N0YA 3T06A 5CLLB 3O96A 2Y8GA 4HDOA 4XWXA 2I1KA 3AU4A 1NU2A 1MPHA 1WG7A 4HAXB 5DI9B 3WYFB 2COCA 4MT7A 4HAUB 4Z2MB 2ADZA 5HE3A 3KY9A 1LW3A 1FB8A 2YVCA 1BTKA 4KHBB 3QIJA 4Y94A 1XKEA 4IFSA 2YSZA 2Z0PA 5KCVA 3KSYA 3A8QA 4K81A 5D3XA 3VIAA 2UVMA 3KZ1A 2RVBB 2LKOA 3PZDA 2CY4A 4BBKA 2DKPA 1DDMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TXD A;  1FGY A;  2J0M A;  4HAT B;  1U27 A;  2QKM A;  5HE0 A;  5C6R A;  2EMT A;  2YRY A;  3OAN A;  1UNP A;  2N23 A;  5C16 A;  1E5W A;  4PQ0 A;  2EC1 A;  2W2X D;  1I7A A;  2X18 A;  2MWN B;  1AWE A;  3PEG A;  1ZM0 A;  5HE1 A;  2D2Q A;  4GZU A;  1X86 A;  1SGH A;  1J0W A;  2W2X C;  2MKR A;  2NMB A;  2D10 A;  2DN6 A;  3GYP A;  2H7E A;  2CAY A;  2R09 A;  2KUP A;  2DLW A;  1X11 A;  5JP4 A;  3CIK A;  1V89 A;  1PLS A;  2YS5 A;  1X1G A;  1V88 A;  2RLO A;  1PMS A;  3TW1 A;  1Y5O A;  2DA0 A;  4A6K A;  1NTY A;  2YT0 A;  3RCP A;  3QWM A;  2DHJ A;  1XR0 B;  4PNK A;  3P6A A;  1OQN A;  3U8Z A;  2ROZ B;  1ISN A;  1K5D B;  1MK9 B;  1U5D A;  2VSZ A;  4L6E A;  2DX1 A;  5KQ4 A;  2AL6 A;  1UNQ A;  1FOE A;  1BWN A;  1DBH A;  2OQB A;  1P5T A;  2GCJ A;  1RJ2 A;  3ODO A;  3AJ4 A;  2GCL A;  4K17 A;  1WJ1 A;  5DHA B;  3MPX A;  1MIX A;  2L2I A;  4WJ7 A;  4YON A;  1KZG A;  5J3Y A;  5DIF B;  3TVV A;  1M7R A;  2D9X A;  4IOY X;  5L81 A;  1XOD A;  2CY5 A;  3BIN A;  4KHO A;  4KVG B;  5D27 A;  5JLJ B;  5LOP B;  2FJL A;  2DKQ A;  2P0F A;  1WVH A;  1U29 A;  3PVL A;  1KZ7 A;  2YS1 A;  4WVF B;  2Z0Q A;  1X05 A;  5GOW B;  2LUL A;  1WGQ A;  4GXB A;  4NY0 A;  1ZVR A;  3TCA A;  1EVH A;  2HE7 A;  1UEF A;  4D0N B;  4F7U P;  2DTC A;  4HHV A;  2G35 A;  3A98 B;  2AEH A;  1LB1 A;  1V61 A;  3M1I B;  4A5K A;  1DYN A;  1V5P A;  3DXD A;  2D9W A;  3KRX A;  2DHI A;  5EFX A;  2L1C A;  4C0A A;  1K5G B;  3V5W A;  3FM8 C;  4DX9 0;  3SYX A;  1U5G A;  3F0W A;  4GN1 A;  4WSF A;  2V76 A;  5CLQ B;  4A6F B;  3FEH A;  4EKU A;  2JP2 A;  2P8V A;  5FI1 A;  4EJN A;  3D8D A;  3PP2 A;  4A6F A;  1I2H A;  4HB2 B;  2COA A;  5C5B A;  4CYE A;  2LOZ A;  4HB4 B;  2HTH B;  4H8S A;  2K2U A;  1U2B A;  1MIZ B;  4KAX B;  1PFJ A;  3ODX A;  1P6S A;  2I5C A;  1WGU A;  5D3V A;  1N3H A;  3TFM A;  4CHM A;  1AQC A;  1B55 A;  4A6H A;  3KRW A;  2ELB A;  4HAW B;  4CHJ A;  1J19 A;  4HAZ B;  2ROV A;  2RUK B;  1QQG A;  4K2P A;  3AU5 A;  3D8F A;  2LG1 A;  3IVF A;  1RRP B;  4B6H A;  2M38 A;  2E2X A;  3SUZ A;  2H7D A;  2MFQ A;  3HQC A;  3SNH A;  2YF0 A;  3HW2 B;  2COD A;  3SO6 A;  1P3R A;  2DX5 A;  5KQ1 A;  1EGX A;  2PZ1 A;  4DX8 A;  1M7E A;  2Y7B A;  4HAV B;  1FHW A;  2GJY A;  2J0K A;  2KGX B;  3ODW A;  4ZRK A;  1XD4 A;  4IAP A;  3P7Z A;  1UPR A;  1DDW A;  3N7C A;  1W1H A;  4TKN A;  3TO1 A;  3PG7 A;  3ULC A;  1GG3 A;  2IFS A;  4P7I A;  1OMW A;  1ZSQ A;  5DH9 B;  3DXC A;  2Z0O A;  2EMS A;  1MAI A;  4HB3 B;  4EMO A;  3GYO A;  2GS0 A;  3PVU A;  4NSW A;  1DDV A;  1BTN A;  1SHC A;  1EAZ A;  5FI0 A;  2RNR B;  2YT1 A;  4HDQ A;  2D9Y A;  1TJ6 A;  2D9Z A;  1FAO A;  4HAY B;  1WI1 A;  1KI1 B;  2Y8F A;  2J59 M;  5JHH A;  1Y19 B;  1Z87 A;  4YL8 A;  5JHG A;  4MK0 A;  2NZ8 B;  2D9V A;  2EJ8 A;  1X1F A;  2XQN M;  2MDX A;  3LJU X;  4KHA A;  3WA0 A;  2D4Q A;  2J0J A;  3CXB B;  3PVW A;  2RSG A;  2LOX A;  3X23 A;  1DRO A;  1IRS A;  4ZRI A;  2M14 A;  5LON B;  1WJM A;  3DXE A;  3ZVR A;  1MKE A;  5HE2 A;  4DBB A;  4K2O A;  2R0D A;  3D8E A;  2W2W A;  2VKI A;  1Q67 A;  3MDB C;  3A8P A;  2UZR A;  5J3T A;  1V5M A;  1NTV A;  1UPQ A;  2K00 A;  3UZT A;  3U7D A;  1V5U A;  1MK7 B;  3G9W A;  5J3Q A;  3FSS A;  5C5B B;  1XCG A;  1FHX A;  4MY6 A;  1TQZ A;  3BJI A;  1W1G A;  4GPT B;  3VOQ A;  1NI2 A;  3ZDT A;  1FHO A;  1UNR A;  2VRW B;  4HB0 B;  3NSU A;  1GC7 A;  4TYZ A;  3F5R A;  2KCJ A;  2OTX A;  5C79 A;  2UZS A;  4ZRJ A;  3ULB A;  2Q13 A;  1BAK A;  1U5E A;  3QBV B;  1H4R A;  1OY2 A;  2IYB A;  1W1D A;  4DXA B;  1XX0 A;  2I5F A;  4F7G A;  4GMX B;  2D11 A;  2RGN B;  2DHK A;  2DYN A;  3PSC A;  2COF A;  1H10 A;  1FGZ A;  2BCJ A;  2P0H A;  4GMV A;  5DHF B;  1ZC3 B;  5D3Y A;  4Z2N A;  3ML4 A;  1GC6 A;  2P0D A;  2DYQ A;  2YS3 A;  1QC6 A;  1ZC4 B;  1U5F A;  2DFK A;  5D3W A;  4F7H A;  2CRF A;  2LYD A;  2I1J A;  2ELA A;  2K2J A;  2QKL A;  2ZPY A;  3SV1 A;  1EF1 A;  3HK0 A;  2N0Y A;  3T06 A;  5CLL B;  3O96 A;  2Y8G A;  4HDO A;  4XWX A;  2I1K A;  3AU4 A;  1NU2 A;  1MPH A;  1WG7 A;  4HAX B;  5DI9 B;  3WYF B;  2COC A;  4MT7 A;  4HAU B;  4Z2M B;  2ADZ A;  5HE3 A;  3KY9 A;  1LW3 A;  1FB8 A;  2YVC A;  1BTK A;  4KHB B;  3QIJ A;  4Y94 A;  1XKE A;  4IFS A;  2YSZ A;  2Z0P A;  5KCV A;  3KSY A;  3A8Q A;  4K81 A;  5D3X A;  3VIA A;  2UVM A;  3KZ1 A;  2RVB B;  2LKO A;  3PZD A;  2CY4 A;  4BBK A;  2DKP A;  1DDM A; 
#chains in the Genus database with same CATH topology
 1TXD A;  1FGY A;  2J0M A;  4HAT B;  1U27 A;  2QKM A;  5HE0 A;  5C6R A;  2EMT A;  2YRY A;  3HSA A;  3OAN A;  1UNP A;  4GNK B;  2N23 A;  5C16 A;  1E5W A;  4PQ0 A;  2EC1 A;  2YT2 A;  2W2X D;  1I7A A;  2X18 A;  2MWN B;  1AWE A;  3PEG A;  1ZM0 A;  5HE1 A;  2D2Q A;  5LG4 B;  4GZU A;  1X86 A;  1SGH A;  4QJ5 B;  1J0W A;  2W2X C;  2MKR A;  2NMB A;  2D10 A;  2DN6 A;  3GYP A;  2H7E A;  2CAY A;  2R09 A;  2KUP A;  3NWF A;  2DLW A;  1X11 A;  5JP4 A;  3CIK A;  1V89 A;  1PLS A;  2YS5 A;  1X1G A;  1V88 A;  2RLO A;  1PMS A;  3TW1 A;  1Y5O A;  2DA0 A;  4A6K A;  5I2M A;  1NTY A;  2YT0 A;  3RCP A;  3QWM A;  2DHJ A;  1XR0 B;  4PNK A;  3P6A A;  1OQN A;  3U8Z A;  2ROZ B;  1ISN A;  1K5D B;  1MK9 B;  1U5D A;  2VSZ A;  4L6E A;  2DX1 A;  5KQ4 A;  2AL6 A;  1UNQ A;  1FOE A;  1BWN A;  1DBH A;  2OQB A;  1P5T A;  2GCJ A;  1RJ2 A;  2RRF A;  2Z14 A;  3ODO A;  3AJ4 A;  2GCL A;  4K17 A;  1WJ1 A;  5DHA B;  3MPX A;  1MIX A;  2L2I A;  4WJ7 A;  4YON A;  1KZG A;  5J3Y A;  5DIF B;  3TVV A;  1M7R A;  2D9X A;  4IOY X;  5L81 A;  1XOD A;  2CY5 A;  3BIN A;  4KHO A;  4KVG B;  5D27 A;  5JLJ B;  5LOP B;  2FJL A;  2DKQ A;  2P0F A;  1WVH A;  1U29 A;  1KZ7 A;  3PVL A;  2YS1 A;  4WVF B;  3OHM B;  2Z0Q A;  1X05 A;  5GOW B;  2LUL A;  1WGQ A;  4GXB A;  4NY0 A;  1ZVR A;  3TCA A;  1EVH A;  2HE7 A;  1UEF A;  3NWA A;  4D0N B;  4F7U P;  2DTC A;  4HHV A;  3NWD A;  2G35 A;  3A98 B;  4OSN A;  2AEH A;  1LB1 A;  1V61 A;  3M1I B;  4A5K A;  1DYN A;  1V5P A;  3DXD A;  2D9W A;  3KRX A;  2DHI A;  5EFX A;  2L1C A;  4C0A A;  1K5G B;  3V5W A;  3FM8 C;  4DX9 0;  3SYX A;  1U5G A;  3F0W A;  4GN1 A;  4WSF A;  4HSI A;  2V76 A;  5CLQ B;  4A6F B;  3FEH A;  4EKU A;  2JP2 A;  2R2Y A;  2P8V A;  5FI1 A;  4EJN A;  2KIG A;  3D8D A;  3PP2 A;  4A6F A;  1I2H A;  4HB2 B;  2Z4D A;  4QJ3 B;  2COA A;  3U12 A;  5C5B A;  4CYE A;  2LOZ A;  4HB4 B;  2HTH B;  4H8S A;  2K2U A;  1U2B A;  1MIZ B;  4KAX B;  1PFJ A;  3ODX A;  1P6S A;  2I5C A;  1WGU A;  5D3V A;  1N3H A;  3TFM A;  4CHM A;  1AQC A;  1B55 A;  4A6H A;  3KRW A;  1MI1 A;  3FVC A;  2ELB A;  4L1R A;  4HAW B;  4CHJ A;  1J19 A;  4HAZ B;  5M4Y B;  2ROV A;  2RUK B;  2KUQ A;  1QQG A;  4K2P A;  3AU5 A;  3D8F A;  2LG1 A;  3IVF A;  1RRP B;  4B6H A;  2M38 A;  2E2X A;  3SUZ A;  2H7D A;  2MFQ A;  3HQC A;  3SNH A;  2YF0 A;  3HW2 B;  3DCX A;  2COD A;  3SO6 A;  1P3R A;  2DX5 A;  5KQ1 A;  1EGX A;  2PZ1 A;  4DX8 A;  1M7E A;  2Y7B A;  4HAV B;  4QJ4 B;  1FHW A;  2GJY A;  2J0K A;  2KGX B;  3ODW A;  4ZRK A;  1XD4 A;  4IAP A;  3P7Z A;  1UPR A;  1DDW A;  3N7C A;  1W1H A;  4TKN A;  3TO1 A;  3PG7 A;  3ULC A;  1GG3 A;  2IFS A;  4P7I A;  1OMW A;  1ZSQ A;  5DH9 B;  3DXC A;  2Z0O A;  2EMS A;  4D6W A;  1MAI A;  2K8E A;  4HB3 B;  4EMO A;  3GYO A;  2GS0 A;  3PVU A;  4NSW A;  3NW8 A;  1DDV A;  1BTN A;  1SHC A;  1EAZ A;  5FI0 A;  2RNR B;  2YT1 A;  4HDQ A;  2D9Y A;  1TJ6 A;  2D9Z A;  1FAO A;  4HAY B;  1WI1 A;  1ZYI A;  1KI1 B;  2Y8F A;  2J59 M;  5JHH A;  1Y19 B;  1Z87 A;  4YL8 A;  5JHG A;  4MK0 A;  2NZ8 B;  2D9V A;  2EJ8 A;  1X1F A;  2XQN M;  2MDX A;  3LJU X;  4KHA A;  3WA0 A;  2D4Q A;  2J0J A;  3CXB B;  3PVW A;  2RSG A;  2LOX A;  3X23 A;  1DRO A;  1IRS A;  4ZRI A;  2M14 A;  5LON B;  2ZKM X;  1WJM A;  5IRS A;  3DXE A;  3ZVR A;  4KHB A;  1MKE A;  5HE2 A;  4DBB A;  4K2O A;  2R0D A;  3D8E A;  2W2W A;  2VKI A;  1Q67 A;  3MDB C;  3A8P A;  2UZR A;  5J3T A;  1V5M A;  1NTV A;  1UPQ A;  2K00 A;  5I2S A;  3UZT A;  3U7D A;  1V5U A;  1MK7 B;  3B77 A;  4GOU A;  3G9W A;  5J3Q A;  3FSS A;  5C5B B;  3HIE A;  1XCG A;  1FHX A;  4MY6 A;  1TQZ A;  3BJI A;  1W1G A;  4GPT B;  3VOQ A;  1NI2 A;  3ZDT A;  1FHO A;  1UNR A;  2VRW B;  4HB0 B;  3NSU A;  1GC7 A;  4TYZ A;  3F5R A;  2GUM A;  2KCJ A;  2OTX A;  5C79 A;  2UZS A;  4ZRJ A;  3ULB A;  2Q13 A;  4DIX A;  1BAK A;  1U5E A;  3QBV B;  1H4R A;  1OY2 A;  2IYB A;  1W1D A;  4DXA B;  1XX0 A;  2I5F A;  4F7G A;  4GMX B;  2D11 A;  2RGN B;  2DHK A;  2DYN A;  3PSC A;  2COF A;  2Z59 A;  1H10 A;  1FGZ A;  2BCJ A;  2K49 A;  2P0H A;  4GMV A;  5DHF B;  2NBV A;  1ZC3 B;  5D3Y A;  4Z2N A;  4CSQ A;  3ML4 A;  1GC6 A;  2P0D A;  2DYQ A;  3A58 A;  2YS3 A;  2FJU B;  1QC6 A;  1ZC4 B;  1U5F A;  2DFK A;  5D3W A;  4F7H A;  2KIE A;  2CRF A;  2LYD A;  2I1J A;  1T77 A;  2ELA A;  2K2J A;  2QKL A;  2ZPY A;  4QXA B;  1EF1 A;  3SV1 A;  3HK0 A;  2N0Y A;  3T06 A;  5CLL B;  3O96 A;  2Y8G A;  4HDO A;  4XWX A;  2I1K A;  3AU4 A;  1NU2 A;  1MPH A;  1WG7 A;  4HAX B;  5DI9 B;  3WYF B;  2COC A;  4MT7 A;  4HAU B;  4Z2M B;  2ADZ A;  2KR0 A;  5HE3 A;  3KY9 A;  1LW3 A;  1FB8 A;  2YVC A;  1BTK A;  4KHB B;  3QIJ A;  4Y94 A;  1XKE A;  4IFS A;  4OT1 A;  2YSZ A;  2Z0P A;  5KCV A;  3KSY A;  3A8Q A;  4K81 A;  5D3X A;  3VIA A;  2UVM A;  3KZ1 A;  2RVB B;  2Z13 A;  2LKO A;  3PZD A;  2CY4 A;  4BBK A;  2DKP A;  1DDM A; 
#chains in the Genus database with same CATH homology
 1TXD A;  1FGY A;  2J0M A;  4HAT B;  1U27 A;  2QKM A;  5HE0 A;  5C6R A;  2EMT A;  2YRY A;  3OAN A;  1UNP A;  2N23 A;  5C16 A;  1E5W A;  4PQ0 A;  2EC1 A;  2W2X D;  1I7A A;  2X18 A;  2MWN B;  1AWE A;  3PEG A;  1ZM0 A;  5HE1 A;  2D2Q A;  4GZU A;  1X86 A;  1SGH A;  1J0W A;  2W2X C;  2MKR A;  2NMB A;  2D10 A;  2DN6 A;  3GYP A;  2H7E A;  2CAY A;  2R09 A;  2KUP A;  2DLW A;  1X11 A;  5JP4 A;  3CIK A;  1V89 A;  1PLS A;  2YS5 A;  1X1G A;  1V88 A;  2RLO A;  1PMS A;  3TW1 A;  1Y5O A;  2DA0 A;  4A6K A;  1NTY A;  2YT0 A;  3RCP A;  3QWM A;  2DHJ A;  1XR0 B;  4PNK A;  3P6A A;  1OQN A;  3U8Z A;  2ROZ B;  1ISN A;  1K5D B;  1MK9 B;  1U5D A;  2VSZ A;  4L6E A;  2DX1 A;  5KQ4 A;  2AL6 A;  1UNQ A;  1FOE A;  1BWN A;  1DBH A;  2OQB A;  1P5T A;  2GCJ A;  1RJ2 A;  3ODO A;  3AJ4 A;  2GCL A;  4K17 A;  1WJ1 A;  5DHA B;  3MPX A;  1MIX A;  2L2I A;  4WJ7 A;  4YON A;  1KZG A;  5J3Y A;  5DIF B;  3TVV A;  1M7R A;  2D9X A;  4IOY X;  5L81 A;  1XOD A;  2CY5 A;  3BIN A;  4KHO A;  4KVG B;  5D27 A;  5JLJ B;  5LOP B;  2FJL A;  2DKQ A;  2P0F A;  1WVH A;  1U29 A;  3PVL A;  1KZ7 A;  2YS1 A;  4WVF B;  2Z0Q A;  1X05 A;  5GOW B;  2LUL A;  1WGQ A;  4GXB A;  4NY0 A;  1ZVR A;  3TCA A;  1EVH A;  2HE7 A;  1UEF A;  4D0N B;  4F7U P;  2DTC A;  4HHV A;  2G35 A;  3A98 B;  2AEH A;  1LB1 A;  1V61 A;  3M1I B;  4A5K A;  1DYN A;  1V5P A;  3DXD A;  2D9W A;  3KRX A;  2DHI A;  5EFX A;  2L1C A;  4C0A A;  1K5G B;  3V5W A;  3FM8 C;  4DX9 0;  3SYX A;  1U5G A;  3F0W A;  4GN1 A;  4WSF A;  2V76 A;  5CLQ B;  4A6F B;  3FEH A;  4EKU A;  2JP2 A;  2P8V A;  5FI1 A;  4EJN A;  3D8D A;  3PP2 A;  4A6F A;  1I2H A;  4HB2 B;  2COA A;  5C5B A;  4CYE A;  2LOZ A;  4HB4 B;  2HTH B;  4H8S A;  2K2U A;  1U2B A;  1MIZ B;  4KAX B;  1PFJ A;  3ODX A;  1P6S A;  2I5C A;  1WGU A;  5D3V A;  1N3H A;  3TFM A;  4CHM A;  1AQC A;  1B55 A;  4A6H A;  3KRW A;  2ELB A;  4HAW B;  4CHJ A;  1J19 A;  4HAZ B;  2ROV A;  2RUK B;  1QQG A;  4K2P A;  3AU5 A;  3D8F A;  2LG1 A;  3IVF A;  1RRP B;  4B6H A;  2M38 A;  2E2X A;  3SUZ A;  2H7D A;  2MFQ A;  3HQC A;  3SNH A;  2YF0 A;  3HW2 B;  2COD A;  3SO6 A;  1P3R A;  2DX5 A;  5KQ1 A;  1EGX A;  2PZ1 A;  4DX8 A;  1M7E A;  2Y7B A;  4HAV B;  1FHW A;  2GJY A;  2J0K A;  2KGX B;  3ODW A;  4ZRK A;  1XD4 A;  4IAP A;  3P7Z A;  1UPR A;  1DDW A;  3N7C A;  1W1H A;  4TKN A;  3TO1 A;  3PG7 A;  3ULC A;  1GG3 A;  2IFS A;  4P7I A;  1OMW A;  1ZSQ A;  5DH9 B;  3DXC A;  2Z0O A;  2EMS A;  1MAI A;  4HB3 B;  4EMO A;  3GYO A;  2GS0 A;  3PVU A;  4NSW A;  1DDV A;  1BTN A;  1SHC A;  1EAZ A;  5FI0 A;  2RNR B;  2YT1 A;  4HDQ A;  2D9Y A;  1TJ6 A;  2D9Z A;  1FAO A;  4HAY B;  1WI1 A;  1KI1 B;  2Y8F A;  2J59 M;  5JHH A;  1Y19 B;  1Z87 A;  4YL8 A;  5JHG A;  4MK0 A;  2NZ8 B;  2D9V A;  2EJ8 A;  1X1F A;  2XQN M;  2MDX A;  3LJU X;  4KHA A;  3WA0 A;  2D4Q A;  2J0J A;  3CXB B;  3PVW A;  2RSG A;  2LOX A;  3X23 A;  1DRO A;  1IRS A;  4ZRI A;  2M14 A;  5LON B;  1WJM A;  3DXE A;  3ZVR A;  1MKE A;  5HE2 A;  4DBB A;  4K2O A;  2R0D A;  3D8E A;  2W2W A;  2VKI A;  1Q67 A;  3MDB C;  3A8P A;  2UZR A;  5J3T A;  1V5M A;  1NTV A;  1UPQ A;  2K00 A;  3UZT A;  3U7D A;  1V5U A;  1MK7 B;  3G9W A;  5J3Q A;  3FSS A;  5C5B B;  1XCG A;  1FHX A;  4MY6 A;  1TQZ A;  3BJI A;  1W1G A;  4GPT B;  3VOQ A;  1NI2 A;  3ZDT A;  1FHO A;  1UNR A;  2VRW B;  4HB0 B;  3NSU A;  1GC7 A;  4TYZ A;  3F5R A;  2KCJ A;  2OTX A;  5C79 A;  2UZS A;  4ZRJ A;  3ULB A;  2Q13 A;  1BAK A;  1U5E A;  3QBV B;  1H4R A;  1OY2 A;  2IYB A;  1W1D A;  4DXA B;  1XX0 A;  2I5F A;  4F7G A;  4GMX B;  2D11 A;  2RGN B;  2DHK A;  2DYN A;  3PSC A;  2COF A;  1H10 A;  1FGZ A;  2BCJ A;  2P0H A;  4GMV A;  5DHF B;  1ZC3 B;  5D3Y A;  4Z2N A;  3ML4 A;  1GC6 A;  2P0D A;  2DYQ A;  2YS3 A;  1QC6 A;  1ZC4 B;  1U5F A;  2DFK A;  5D3W A;  4F7H A;  2CRF A;  2LYD A;  2I1J A;  2ELA A;  2K2J A;  2QKL A;  2ZPY A;  3SV1 A;  1EF1 A;  3HK0 A;  2N0Y A;  3T06 A;  5CLL B;  3O96 A;  2Y8G A;  4HDO A;  4XWX A;  2I1K A;  3AU4 A;  1NU2 A;  1MPH A;  1WG7 A;  4HAX B;  5DI9 B;  3WYF B;  2COC A;  4MT7 A;  4HAU B;  4Z2M B;  2ADZ A;  5HE3 A;  3KY9 A;  1LW3 A;  1FB8 A;  2YVC A;  1BTK A;  4KHB B;  3QIJ A;  4Y94 A;  1XKE A;  4IFS A;  2YSZ A;  2Z0P A;  5KCV A;  3KSY A;  3A8Q A;  4K81 A;  5D3X A;  3VIA A;  2UVM A;  3KZ1 A;  2RVB B;  2LKO A;  3PZD A;  2CY4 A;  4BBK A;  2DKP A;  1DDM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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