5D3XA

Crystal structure of the p-rex1 ph domain with inositol-(1,3,4,5)-tetrakisphosphate bound
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
165
structure length
151
Chain Sequence
GEFEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKLGMERDAY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Lipid binding protein
molecule keywords Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac excha
publication title Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
pubmed doi rcsb
source organism Homo sapiens
total genus 46
structure length 151
sequence length 165
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-08-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 5d3xA00
1DDMA 1X11A 2J0JA 3PSCA 4HHVA 2ELBA 2V76A 3KRXA 4HB4B 2MWNB 2ROVA 2I1JA 3ODXA 3ODOA 2P0FA 2RLOA 5DHAB 5D3YA 4NSWA 1QC6A 2IFSA 3HW2B 2Z0PA 3UZTA 4IFSA 2D2QA 3BINA 4ZRIA 1XCGA 1MIXA 1MK9B 3QBVB 2DFKA 2VRWB 3U8ZA 2LYDA 5KCVA 4ZRKA 2MKRA 4PNKA 1ZC3B 1IRSA 2I5FA 1UNPA 3SNHA 2YT1A 2D9YA 2K2UA 2DKQA 1UNRA 1ZC4B 2MFQA 2HE7A 1X1FA 1FOEA 2QKMA 2P0HA 5JHHA 4Y94A 1V5PA 4MK0A 5J3TA 1LB1A 2Q13A 5FI0A 1W1HA 5DH9B 3DXCA 2YS5A 3AJ4A 1ZM0A 4MY6A 5JP4A 1B55A 1ZSQA 5LOPB 2I1KA 1KI1B 3SUZA 1FB8A 1Z87A 4HDQA 2KUPA 3MDBC 3KY9A 1M7EA 2GCLA 3PZDA 2YVCA 1E5WA 2ADZA 1TQZA 3N7CA 1V88A 1X86A 2Y8GA 2GS0A 4DX90 3QWMA 1EGXA 2D9VA 3SYXA 2PZ1A 5HE2A 2QKLA 2YRYA 1W1DA 2Y7BA 2D9WA 5CLQB 2EJ8A 5C6RA 2DYQA 1EAZA 3O96A 4IAPA 4K17A 1RRPB 1V5MA 2GCJA 4HB0B 1U5EA 2LG1A 1NU2A 3VIAA 4DBBA 2KCJA 4D0NB 3HK0A 3DXEA 2N0YA 2OTXA 2MDXA 4CHMA 3F5RA 2DHKA 4GN1A 1NI2A 1MAIA 1PMSA 3BJIA 3PG7A 3A98B 2Z0QA 2Z0OA 2DA0A 1U5GA 1U2BA 2EMSA 2JP2A 3GYOA 2L1CA 4HAZB 3D8DA 5GOWB 4A6FA 5HE3A 3WYFB 3TW1A 1NTVA 3D8FA 5CLLB 4HAXB 1FHOA 3ODWA 2DX1A 3IVFA 5KQ1A 5LONB 4EJNA 1BAKA 5JHGA 3TVVA 4GXBA 3NSUA 1Y19B 4K2OA 1WVHA 2ELAA 1MK7B 4GZUA 4KHBB 1WGQA 4IOYX 5DHFB 2LULA 5D3VA 3GYPA 1UEFA 5J3YA 2DTCA 1P6SA 3P7ZA 3FEHA 3SV1A 3PP2A 2DLWA 5KQ4A 1SHCA 1AQCA 4DX8A 2K00A 1DROA 1W1GA 2M38A 3ML4A 3KSYA 2J59M 3ZVRA 2RVBB 2GJYA 4HATB 2DHIA 4EMOA 3OANA 2DKPA 3DXDA 2NZ8B 2W2XD 5HE1A 1Y5OA 5HE0A 5DIFB 5C5BB 1ISNA 4HAYB 5FI1A 1EF1A 1P3RA 4Z2MB 3U7DA 2YS3A 1BTNA 1TXDA 4HDOA 2VKIA 1GC7A 2DHJA 1WG7A 1U5DA 2DN6A 4F7UP 4GMVA 2ZPYA 4L6EA 1TJ6A 2UZSA 4H8SA 2FJLA 1KZ7A 1OY2A 1PFJA 3AU4A 2RGNB 4YL8A 1KZGA 4EKUA 1WJ1A 3RCPA 4K81A 1UPRA 2D9XA 3SO6A 3FM8C 1RJ2A 2RUKB 4K2PA 3M1IB 3ULCA 1V61A 3ULBA 2CODA 2RSGA 1DDVA 2COFA 1K5GB 2XQNM 3HQCA 3PEGA 5C79A 4GMXB 3F0WA 3ZDTA 5EFXA 2L2IA 3TO1A 2LKOA 5D27A 1QQGA 3QIJA 1UPQA 1X1GA 1H4RA 2Y8FA 1J0WA 5D3WA 1FHXA 3CIKA 2H7EA 3D8EA 1SGHA 3WA0A 1FGZA 2DX5A 4Z2NA 2AL6A 2D4QA 2J0MA 1LW3A 4A5KA 2D10A 3G9WA 4HB2B 1NTYA 1MPHA 1FAOA 2CRFA 4PQ0A 1UNQA 2UZRA 3CXBB 2IYBA 2CY5A 1K5DB 1OQNA 4ZRJA 2DYNA 1PLSA 3X23A 4HAVB 4HAUB 1H10A 2HTHB 1EVHA 1V89A 2COCA 1U5FA 1WJMA 2K2JA 2UVMA 3KZ1A 2YSZA 4BBKA 5D3XA 1U27A 2W2XC 4HB3B 4KVGB 1V5UA 2J0KA 3TFMA 2H7DA 2X18A 1P5TA 2E2XA 1X05A 2CAYA 3P6AA 2M14A 2COAA 5L81A 1WI1A 1J19A 2AEHA 2EC1A 2BCJA 2P8VA 4CYEA 1AWEA 2RNRB 2W2WA 3VOQA 1XX0A 3V5WA 3PVLA 2NMBA 2LOZA 1FGYA 4WJ7A 4A6HA 5JLJB 3PVUA 2YT0A 1U29A 2EMTA 2G35A 4YONA 2VSZA 2LOXA 2OQBA 4WSFA 4F7HA 3A8PA 2D9ZA 3FSSA 2ROZB 3KRWA 2CY4A 2D11A 4CHJA 1DDWA 5DI9B 1BTKA 4A6FB 3A8QA 1I2HA 1DBHA 4F7GA 4HAWB 4GPTB 4KHAA 2P0DA 4MT7A 2YS1A 3PVWA 5J3QA 2N23A 4KAXB 4DXAB 1FHWA 5C16A 5C5BA 4NY0A 1N3HA 1OMWA 4XWXA 3AU5A 1M7RA 1BWNA 1XR0B 2KGXB 3TCAA 1MIZB 1MKEA 4C0AA 4TYZA 4KHOA 4WVFB 3T06A 1Q67A 3MPXA 1XODA 1ZVRA 1GC6A 1GG3A 1I7AA 1XKEA 2R09A 1DYNA 2R0DA 4B6HA 1WGUA 3LJUX 4P7IA 4TKNA 1XD4A 2I5CA 4A6KA 2YF0A
chains in the Genus database with same CATH superfamily
1DDMA 1X11A 2J0JA 3PSCA 4HHVA 2ELBA 2V76A 5LG4B 3KRXA 4HB4B 2MWNB 3HSAA 2ROVA 2I1JA 3ODXA 3ODOA 2P0FA 2RLOA 5DHAB 2NBVA 5D3YA 4NSWA 1QC6A 2IFSA 3HW2B 2Z0PA 3UZTA 4IFSA 2D2QA 3BINA 4ZRIA 4GOUA 1XCGA 1MIXA 1MK9B 3QBVB 2DFKA 2VRWB 3U8ZA 2LYDA 5KCVA 3HIEA 4ZRKA 2KR0A 2MKRA 4PNKA 1ZC3B 1IRSA 2I5FA 1UNPA 3SNHA 2YT1A 2D9YA 2K2UA 4QJ3B 2DKQA 1UNRA 1ZC4B 2FJUB 2MFQA 2HE7A 1X1FA 1FOEA 2QKMA 2P0HA 5JHHA 4Y94A 1V5PA 4MK0A 5J3TA 2Z59A 1LB1A 2Q13A 5FI0A 1W1HA 2K49A 3DXCA 4GNKB 5DH9B 2YS5A 3AJ4A 1ZM0A 4MY6A 5JP4A 1B55A 1ZSQA 5LOPB 2I1KA 1KI1B 3SUZA 1FB8A 1Z87A 4HDQA 2KUPA 3MDBC 3KY9A 1M7EA 2GCLA 3PZDA 2YVCA 1E5WA 2ADZA 1TQZA 3N7CA 1V88A 1X86A 2Y8GA 2GS0A 4DX90 4CSQA 3QWMA 1EGXA 2D9VA 3SYXA 2PZ1A 5HE2A 2QKLA 2YRYA 1W1DA 2Y7BA 2D9WA 5CLQB 2EJ8A 5C6RA 3B77A 2DYQA 1EAZA 3O96A 4IAPA 4K17A 1RRPB 1V5MA 2GCJA 4HB0B 1U5EA 2LG1A 5M4YB 1NU2A 3VIAA 4DBBA 2KCJA 4D0NB 3HK0A 3DXEA 2N0YA 2OTXA 2KUQA 2MDXA 2R2YA 2GUMA 4CHMA 3F5RA 2DHKA 4GN1A 1NI2A 1MAIA 1PMSA 3A58A 3BJIA 3PG7A 3A98B 2Z0QA 2Z0OA 2DA0A 1U5GA 1U2BA 2EMSA 2JP2A 2Z4DA 3GYOA 2L1CA 4HAZB 3D8DA 5GOWB 4A6FA 5HE3A 3WYFB 3TW1A 1NTVA 3D8FA 1ZYIA 5CLLB 4HAXB 1FHOA 3ODWA 2DX1A 3IVFA 5KQ1A 5LONB 2ZKMX 4EJNA 1BAKA 5JHGA 3TVVA 4GXBA 3NSUA 1Y19B 4K2OA 1WVHA 2ELAA 1MK7B 4GZUA 4KHBB 1WGQA 4IOYX 5DHFB 2LULA 5D3VA 3GYPA 1UEFA 5J3YA 2DTCA 1P6SA 3P7ZA 3FEHA 3SV1A 3PP2A 3NWFA 2DLWA 5KQ4A 1SHCA 1AQCA 2RRFA 4DX8A 2K00A 1DROA 1W1GA 2M38A 3ML4A 3KSYA 2J59M 3ZVRA 2RVBB 2GJYA 4HATB 2DHIA 4EMOA 3OANA 2DKPA 3DXDA 2NZ8B 2W2XD 4QXAB 5HE1A 1Y5OA 4HSIA 5HE0A 5DIFB 5C5BB 1ISNA 4HAYB 5FI1A 1EF1A 5I2MA 1P3RA 4Z2MB 3U7DA 2YS3A 1BTNA 1TXDA 3NW8A 4HDOA 2VKIA 1GC7A 2DHJA 1WG7A 1U5DA 2DN6A 4F7UP 4GMVA 2ZPYA 4L6EA 1TJ6A 2UZSA 4H8SA 2FJLA 1KZ7A 1OY2A 3FVCA 4D6WA 1PFJA 3AU4A 2KIGA 2RGNB 4YL8A 1KZGA 4EKUA 1WJ1A 3RCPA 4K81A 1UPRA 2D9XA 3SO6A 3FM8C 4OT1A 1RJ2A 2RUKB 4K2PA 3M1IB 3ULCA 1V61A 3ULBA 2CODA 2RSGA 1DDVA 2COFA 4DIXA 1K5GB 2XQNM 3HQCA 3PEGA 5C79A 4GMXB 3F0WA 3ZDTA 5EFXA 3NWAA 2L2IA 3TO1A 2LKOA 5D27A 1QQGA 3QIJA 1UPQA 1X1GA 1H4RA 2Y8FA 2Z14A 1J0WA 5D3WA 1FHXA 3CIKA 2H7EA 3D8EA 1SGHA 3WA0A 1FGZA 2DX5A 4Z2NA 2AL6A 2D4QA 2J0MA 1LW3A 4A5KA 1T77A 2D10A 3G9WA 4HB2B 1NTYA 1MPHA 1FAOA 2CRFA 4PQ0A 1UNQA 2UZRA 3CXBB 2IYBA 2CY5A 1K5DB 5I2SA 1OQNA 4ZRJA 2DYNA 1PLSA 3X23A 4HAVB 4HAUB 1H10A 2HTHB 1EVHA 1V89A 2COCA 1U5FA 2K8EA 1WJMA 2K2JA 2UVMA 3KZ1A 2YSZA 4BBKA 5D3XA 1U27A 2W2XC 4HB3B 4KVGB 1V5UA 4QJ4B 2J0KA 3TFMA 2H7DA 2X18A 1P5TA 2E2XA 1X05A 2CAYA 3P6AA 2M14A 2COAA 5L81A 4L1RA 1WI1A 1J19A 2AEHA 2EC1A 2BCJA 2P8VA 4CYEA 1AWEA 2RNRB 2W2WA 3VOQA 1XX0A 4QJ5B 3V5WA 3PVLA 2NMBA 2LOZA 1FGYA 2Z13A 4WJ7A 4A6HA 5JLJB 3PVUA 2YT0A 1U29A 2EMTA 2G35A 4KHBA 4YONA 2VSZA 2LOXA 2OQBA 4WSFA 4F7HA 3A8PA 2KIEA 2D9ZA 3FSSA 2ROZB 3KRWA 2CY4A 2D11A 4CHJA 1DDWA 5DI9B 1BTKA 4A6FB 3A8QA 1I2HA 1MI1A 4OSNA 1DBHA 4F7GA 4HAWB 4GPTB 4KHAA 2P0DA 4MT7A 2YS1A 3DCXA 3PVWA 5J3QA 2N23A 4KAXB 4DXAB 1FHWA 5C16A 5C5BA 4NY0A 1N3HA 1OMWA 4XWXA 3AU5A 1M7RA 3U12A 1BWNA 1XR0B 2KGXB 3TCAA 1MIZB 1MKEA 4C0AA 4TYZA 3OHMB 4KHOA 4WVFB 3T06A 1Q67A 3MPXA 1XODA 1ZVRA 1GC6A 1GG3A 1I7AA 1XKEA 2R09A 1DYNA 2R0DA 4B6HA 1WGUA 3LJUX 4P7IA 4TKNA 5IRSA 2YT2A 1XD4A 2I5CA 4A6KA 3NWDA 2YF0A
chains in the Genus database with same CATH topology
1DDMA 1X11A 2J0JA 3PSCA 4HHVA 2ELBA 2V76A 3KRXA 4HB4B 2MWNB 2ROVA 2I1JA 3ODXA 3ODOA 2P0FA 2RLOA 5DHAB 5D3YA 4NSWA 1QC6A 2IFSA 3HW2B 2Z0PA 3UZTA 4IFSA 2D2QA 3BINA 4ZRIA 1XCGA 1MIXA 1MK9B 3QBVB 2DFKA 2VRWB 3U8ZA 2LYDA 5KCVA 4ZRKA 2MKRA 4PNKA 1ZC3B 1IRSA 2I5FA 1UNPA 3SNHA 2YT1A 2D9YA 2K2UA 2DKQA 1UNRA 1ZC4B 2MFQA 2HE7A 1X1FA 1FOEA 2QKMA 2P0HA 5JHHA 4Y94A 1V5PA 4MK0A 5J3TA 1LB1A 2Q13A 5FI0A 1W1HA 5DH9B 3DXCA 2YS5A 3AJ4A 1ZM0A 4MY6A 5JP4A 1B55A 1ZSQA 5LOPB 2I1KA 1KI1B 3SUZA 1FB8A 1Z87A 4HDQA 2KUPA 3MDBC 3KY9A 1M7EA 2GCLA 3PZDA 2YVCA 1E5WA 2ADZA 1TQZA 3N7CA 1V88A 1X86A 2Y8GA 2GS0A 4DX90 3QWMA 1EGXA 2D9VA 3SYXA 2PZ1A 5HE2A 2QKLA 2YRYA 1W1DA 2Y7BA 2D9WA 5CLQB 2EJ8A 5C6RA 2DYQA 1EAZA 3O96A 4IAPA 4K17A 1RRPB 1V5MA 2GCJA 4HB0B 1U5EA 2LG1A 1NU2A 3VIAA 4DBBA 2KCJA 4D0NB 3HK0A 3DXEA 2N0YA 2OTXA 2MDXA 4CHMA 3F5RA 2DHKA 4GN1A 1NI2A 1MAIA 1PMSA 3BJIA 3PG7A 3A98B 2Z0QA 2Z0OA 2DA0A 1U5GA 1U2BA 2EMSA 2JP2A 3GYOA 2L1CA 4HAZB 3D8DA 5GOWB 4A6FA 5HE3A 3WYFB 3TW1A 1NTVA 3D8FA 5CLLB 4HAXB 1FHOA 3ODWA 2DX1A 3IVFA 5KQ1A 5LONB 4EJNA 1BAKA 5JHGA 3TVVA 4GXBA 3NSUA 1Y19B 4K2OA 1WVHA 2ELAA 1MK7B 4GZUA 4KHBB 1WGQA 4IOYX 5DHFB 2LULA 5D3VA 3GYPA 1UEFA 5J3YA 2DTCA 1P6SA 3P7ZA 3FEHA 3SV1A 3PP2A 2DLWA 5KQ4A 1SHCA 1AQCA 4DX8A 2K00A 1DROA 1W1GA 2M38A 3ML4A 3KSYA 2J59M 3ZVRA 2RVBB 2GJYA 4HATB 2DHIA 4EMOA 3OANA 2DKPA 3DXDA 2NZ8B 2W2XD 5HE1A 1Y5OA 5HE0A 5DIFB 5C5BB 1ISNA 4HAYB 5FI1A 1EF1A 1P3RA 4Z2MB 3U7DA 2YS3A 1BTNA 1TXDA 4HDOA 2VKIA 1GC7A 2DHJA 1WG7A 1U5DA 2DN6A 4F7UP 4GMVA 2ZPYA 4L6EA 1TJ6A 2UZSA 4H8SA 2FJLA 1KZ7A 1OY2A 1PFJA 3AU4A 2RGNB 4YL8A 1KZGA 4EKUA 1WJ1A 3RCPA 4K81A 1UPRA 2D9XA 3SO6A 3FM8C 1RJ2A 2RUKB 4K2PA 3M1IB 3ULCA 1V61A 3ULBA 2CODA 2RSGA 1DDVA 2COFA 1K5GB 2XQNM 3HQCA 3PEGA 5C79A 4GMXB 3F0WA 3ZDTA 5EFXA 2L2IA 3TO1A 2LKOA 5D27A 1QQGA 3QIJA 1UPQA 1X1GA 1H4RA 2Y8FA 1J0WA 5D3WA 1FHXA 3CIKA 2H7EA 3D8EA 1SGHA 3WA0A 1FGZA 2DX5A 4Z2NA 2AL6A 2D4QA 2J0MA 1LW3A 4A5KA 2D10A 3G9WA 4HB2B 1NTYA 1MPHA 1FAOA 2CRFA 4PQ0A 1UNQA 2UZRA 3CXBB 2IYBA 2CY5A 1K5DB 1OQNA 4ZRJA 2DYNA 1PLSA 3X23A 4HAVB 4HAUB 1H10A 2HTHB 1EVHA 1V89A 2COCA 1U5FA 1WJMA 2K2JA 2UVMA 3KZ1A 2YSZA 4BBKA 5D3XA 1U27A 2W2XC 4HB3B 4KVGB 1V5UA 2J0KA 3TFMA 2H7DA 2X18A 1P5TA 2E2XA 1X05A 2CAYA 3P6AA 2M14A 2COAA 5L81A 1WI1A 1J19A 2AEHA 2EC1A 2BCJA 2P8VA 4CYEA 1AWEA 2RNRB 2W2WA 3VOQA 1XX0A 3V5WA 3PVLA 2NMBA 2LOZA 1FGYA 4WJ7A 4A6HA 5JLJB 3PVUA 2YT0A 1U29A 2EMTA 2G35A 4YONA 2VSZA 2LOXA 2OQBA 4WSFA 4F7HA 3A8PA 2D9ZA 3FSSA 2ROZB 3KRWA 2CY4A 2D11A 4CHJA 1DDWA 5DI9B 1BTKA 4A6FB 3A8QA 1I2HA 1DBHA 4F7GA 4HAWB 4GPTB 4KHAA 2P0DA 4MT7A 2YS1A 3PVWA 5J3QA 2N23A 4KAXB 4DXAB 1FHWA 5C16A 5C5BA 4NY0A 1N3HA 1OMWA 4XWXA 3AU5A 1M7RA 1BWNA 1XR0B 2KGXB 3TCAA 1MIZB 1MKEA 4C0AA 4TYZA 4KHOA 4WVFB 3T06A 1Q67A 3MPXA 1XODA 1ZVRA 1GC6A 1GG3A 1I7AA 1XKEA 2R09A 1DYNA 2R0DA 4B6HA 1WGUA 3LJUX 4P7IA 4TKNA 1XD4A 2I5CA 4A6KA 2YF0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DDM A;  1X11 A;  2J0J A;  3PSC A;  4HHV A;  2ELB A;  2V76 A;  3KRX A;  4HB4 B;  2MWN B;  2ROV A;  2I1J A;  3ODX A;  3ODO A;  2P0F A;  2RLO A;  5DHA B;  5D3Y A;  4NSW A;  1QC6 A;  2IFS A;  3HW2 B;  2Z0P A;  3UZT A;  4IFS A;  2D2Q A;  3BIN A;  4ZRI A;  1XCG A;  1MIX A;  1MK9 B;  3QBV B;  2DFK A;  2VRW B;  3U8Z A;  2LYD A;  5KCV A;  4ZRK A;  2MKR A;  4PNK A;  1ZC3 B;  1IRS A;  2I5F A;  1UNP A;  3SNH A;  2YT1 A;  2D9Y A;  2K2U A;  2DKQ A;  1UNR A;  1ZC4 B;  2MFQ A;  2HE7 A;  1X1F A;  1FOE A;  2QKM A;  2P0H A;  5JHH A;  4Y94 A;  1V5P A;  4MK0 A;  5J3T A;  1LB1 A;  2Q13 A;  5FI0 A;  1W1H A;  5DH9 B;  3DXC A;  2YS5 A;  3AJ4 A;  1ZM0 A;  4MY6 A;  5JP4 A;  1B55 A;  1ZSQ A;  5LOP B;  2I1K A;  1KI1 B;  3SUZ A;  1FB8 A;  1Z87 A;  4HDQ A;  2KUP A;  3MDB C;  3KY9 A;  1M7E A;  2GCL A;  3PZD A;  2YVC A;  1E5W A;  2ADZ A;  1TQZ A;  3N7C A;  1V88 A;  1X86 A;  2Y8G A;  2GS0 A;  4DX9 0;  3QWM A;  1EGX A;  2D9V A;  3SYX A;  2PZ1 A;  5HE2 A;  2QKL A;  2YRY A;  1W1D A;  2Y7B A;  2D9W A;  5CLQ B;  2EJ8 A;  5C6R A;  2DYQ A;  1EAZ A;  3O96 A;  4IAP A;  4K17 A;  1RRP B;  1V5M A;  2GCJ A;  4HB0 B;  1U5E A;  2LG1 A;  1NU2 A;  3VIA A;  4DBB A;  2KCJ A;  4D0N B;  3HK0 A;  3DXE A;  2N0Y A;  2OTX A;  2MDX A;  4CHM A;  3F5R A;  2DHK A;  4GN1 A;  1NI2 A;  1MAI A;  1PMS A;  3BJI A;  3PG7 A;  3A98 B;  2Z0Q A;  2Z0O A;  2DA0 A;  1U5G A;  1U2B A;  2EMS A;  2JP2 A;  3GYO A;  2L1C A;  4HAZ B;  3D8D A;  5GOW B;  4A6F A;  5HE3 A;  3WYF B;  3TW1 A;  1NTV A;  3D8F A;  5CLL B;  4HAX B;  1FHO A;  3ODW A;  2DX1 A;  3IVF A;  5KQ1 A;  5LON B;  4EJN A;  1BAK A;  5JHG A;  3TVV A;  4GXB A;  3NSU A;  1Y19 B;  4K2O A;  1WVH A;  2ELA A;  1MK7 B;  4GZU A;  4KHB B;  1WGQ A;  4IOY X;  5DHF B;  2LUL A;  5D3V A;  3GYP A;  1UEF A;  5J3Y A;  2DTC A;  1P6S A;  3P7Z A;  3FEH A;  3SV1 A;  3PP2 A;  2DLW A;  5KQ4 A;  1SHC A;  1AQC A;  4DX8 A;  2K00 A;  1DRO A;  1W1G A;  2M38 A;  3ML4 A;  3KSY A;  2J59 M;  3ZVR A;  2RVB B;  2GJY A;  4HAT B;  2DHI A;  4EMO A;  3OAN A;  2DKP A;  3DXD A;  2NZ8 B;  2W2X D;  5HE1 A;  1Y5O A;  5HE0 A;  5DIF B;  5C5B B;  1ISN A;  4HAY B;  5FI1 A;  1EF1 A;  1P3R A;  4Z2M B;  3U7D A;  2YS3 A;  1BTN A;  1TXD A;  4HDO A;  2VKI A;  1GC7 A;  2DHJ A;  1WG7 A;  1U5D A;  2DN6 A;  4F7U P;  4GMV A;  2ZPY A;  4L6E A;  1TJ6 A;  2UZS A;  4H8S A;  2FJL A;  1KZ7 A;  1OY2 A;  1PFJ A;  3AU4 A;  2RGN B;  4YL8 A;  1KZG A;  4EKU A;  1WJ1 A;  3RCP A;  4K81 A;  1UPR A;  2D9X A;  3SO6 A;  3FM8 C;  1RJ2 A;  2RUK B;  4K2P A;  3M1I B;  3ULC A;  1V61 A;  3ULB A;  2COD A;  2RSG A;  1DDV A;  2COF A;  1K5G B;  2XQN M;  3HQC A;  3PEG A;  5C79 A;  4GMX B;  3F0W A;  3ZDT A;  5EFX A;  2L2I A;  3TO1 A;  2LKO A;  5D27 A;  1QQG A;  3QIJ A;  1UPQ A;  1X1G A;  1H4R A;  2Y8F A;  1J0W A;  5D3W A;  1FHX A;  3CIK A;  2H7E A;  3D8E A;  1SGH A;  3WA0 A;  1FGZ A;  2DX5 A;  4Z2N A;  2AL6 A;  2D4Q A;  2J0M A;  1LW3 A;  4A5K A;  2D10 A;  3G9W A;  4HB2 B;  1NTY A;  1MPH A;  1FAO A;  2CRF A;  4PQ0 A;  1UNQ A;  2UZR A;  3CXB B;  2IYB A;  2CY5 A;  1K5D B;  1OQN A;  4ZRJ A;  2DYN A;  1PLS A;  3X23 A;  4HAV B;  4HAU B;  1H10 A;  2HTH B;  1EVH A;  1V89 A;  2COC A;  1U5F A;  1WJM A;  2K2J A;  2UVM A;  3KZ1 A;  2YSZ A;  4BBK A;  5D3X A;  1U27 A;  2W2X C;  4HB3 B;  4KVG B;  1V5U A;  2J0K A;  3TFM A;  2H7D A;  2X18 A;  1P5T A;  2E2X A;  1X05 A;  2CAY A;  3P6A A;  2M14 A;  2COA A;  5L81 A;  1WI1 A;  1J19 A;  2AEH A;  2EC1 A;  2BCJ A;  2P8V A;  4CYE A;  1AWE A;  2RNR B;  2W2W A;  3VOQ A;  1XX0 A;  3V5W A;  3PVL A;  2NMB A;  2LOZ A;  1FGY A;  4WJ7 A;  4A6H A;  5JLJ B;  3PVU A;  2YT0 A;  1U29 A;  2EMT A;  2G35 A;  4YON A;  2VSZ A;  2LOX A;  2OQB A;  4WSF A;  4F7H A;  3A8P A;  2D9Z A;  3FSS A;  2ROZ B;  3KRW A;  2CY4 A;  2D11 A;  4CHJ A;  1DDW A;  5DI9 B;  1BTK A;  4A6F B;  3A8Q A;  1I2H A;  1DBH A;  4F7G A;  4HAW B;  4GPT B;  4KHA A;  2P0D A;  4MT7 A;  2YS1 A;  3PVW A;  5J3Q A;  2N23 A;  4KAX B;  4DXA B;  1FHW A;  5C16 A;  5C5B A;  4NY0 A;  1N3H A;  1OMW A;  4XWX A;  3AU5 A;  1M7R A;  1BWN A;  1XR0 B;  2KGX B;  3TCA A;  1MIZ B;  1MKE A;  4C0A A;  4TYZ A;  4KHO A;  4WVF B;  3T06 A;  1Q67 A;  3MPX A;  1XOD A;  1ZVR A;  1GC6 A;  1GG3 A;  1I7A A;  1XKE A;  2R09 A;  1DYN A;  2R0D A;  4B6H A;  1WGU A;  3LJU X;  4P7I A;  4TKN A;  1XD4 A;  2I5C A;  4A6K A;  2YF0 A; 
#chains in the Genus database with same CATH topology
 1DDM A;  1X11 A;  2J0J A;  3PSC A;  4HHV A;  2ELB A;  2V76 A;  5LG4 B;  3KRX A;  4HB4 B;  2MWN B;  3HSA A;  2ROV A;  2I1J A;  3ODX A;  3ODO A;  2P0F A;  2RLO A;  5DHA B;  2NBV A;  5D3Y A;  4NSW A;  1QC6 A;  2IFS A;  3HW2 B;  2Z0P A;  3UZT A;  4IFS A;  2D2Q A;  3BIN A;  4ZRI A;  4GOU A;  1XCG A;  1MIX A;  1MK9 B;  3QBV B;  2DFK A;  2VRW B;  3U8Z A;  2LYD A;  5KCV A;  3HIE A;  4ZRK A;  2KR0 A;  2MKR A;  4PNK A;  1ZC3 B;  1IRS A;  2I5F A;  1UNP A;  3SNH A;  2YT1 A;  2D9Y A;  2K2U A;  4QJ3 B;  2DKQ A;  1UNR A;  1ZC4 B;  2FJU B;  2MFQ A;  2HE7 A;  1X1F A;  1FOE A;  2QKM A;  2P0H A;  5JHH A;  4Y94 A;  1V5P A;  4MK0 A;  5J3T A;  2Z59 A;  1LB1 A;  2Q13 A;  5FI0 A;  1W1H A;  2K49 A;  3DXC A;  4GNK B;  5DH9 B;  2YS5 A;  3AJ4 A;  1ZM0 A;  4MY6 A;  5JP4 A;  1B55 A;  1ZSQ A;  5LOP B;  2I1K A;  1KI1 B;  3SUZ A;  1FB8 A;  1Z87 A;  4HDQ A;  2KUP A;  3MDB C;  3KY9 A;  1M7E A;  2GCL A;  3PZD A;  2YVC A;  1E5W A;  2ADZ A;  1TQZ A;  3N7C A;  1V88 A;  1X86 A;  2Y8G A;  2GS0 A;  4DX9 0;  4CSQ A;  3QWM A;  1EGX A;  2D9V A;  3SYX A;  2PZ1 A;  5HE2 A;  2QKL A;  2YRY A;  1W1D A;  2Y7B A;  2D9W A;  5CLQ B;  2EJ8 A;  5C6R A;  3B77 A;  2DYQ A;  1EAZ A;  3O96 A;  4IAP A;  4K17 A;  1RRP B;  1V5M A;  2GCJ A;  4HB0 B;  1U5E A;  2LG1 A;  5M4Y B;  1NU2 A;  3VIA A;  4DBB A;  2KCJ A;  4D0N B;  3HK0 A;  3DXE A;  2N0Y A;  2OTX A;  2KUQ A;  2MDX A;  2R2Y A;  2GUM A;  4CHM A;  3F5R A;  2DHK A;  4GN1 A;  1NI2 A;  1MAI A;  1PMS A;  3A58 A;  3BJI A;  3PG7 A;  3A98 B;  2Z0Q A;  2Z0O A;  2DA0 A;  1U5G A;  1U2B A;  2EMS A;  2JP2 A;  2Z4D A;  3GYO A;  2L1C A;  4HAZ B;  3D8D A;  5GOW B;  4A6F A;  5HE3 A;  3WYF B;  3TW1 A;  1NTV A;  3D8F A;  1ZYI A;  5CLL B;  4HAX B;  1FHO A;  3ODW A;  2DX1 A;  3IVF A;  5KQ1 A;  5LON B;  2ZKM X;  4EJN A;  1BAK A;  5JHG A;  3TVV A;  4GXB A;  3NSU A;  1Y19 B;  4K2O A;  1WVH A;  2ELA A;  1MK7 B;  4GZU A;  4KHB B;  1WGQ A;  4IOY X;  5DHF B;  2LUL A;  5D3V A;  3GYP A;  1UEF A;  5J3Y A;  2DTC A;  1P6S A;  3P7Z A;  3FEH A;  3SV1 A;  3PP2 A;  3NWF A;  2DLW A;  5KQ4 A;  1SHC A;  1AQC A;  2RRF A;  4DX8 A;  2K00 A;  1DRO A;  1W1G A;  2M38 A;  3ML4 A;  3KSY A;  2J59 M;  3ZVR A;  2RVB B;  2GJY A;  4HAT B;  2DHI A;  4EMO A;  3OAN A;  2DKP A;  3DXD A;  2NZ8 B;  2W2X D;  4QXA B;  5HE1 A;  1Y5O A;  4HSI A;  5HE0 A;  5DIF B;  5C5B B;  1ISN A;  4HAY B;  5FI1 A;  1EF1 A;  5I2M A;  1P3R A;  4Z2M B;  3U7D A;  2YS3 A;  1BTN A;  1TXD A;  3NW8 A;  4HDO A;  2VKI A;  1GC7 A;  2DHJ A;  1WG7 A;  1U5D A;  2DN6 A;  4F7U P;  4GMV A;  2ZPY A;  4L6E A;  1TJ6 A;  2UZS A;  4H8S A;  2FJL A;  1KZ7 A;  1OY2 A;  3FVC A;  4D6W A;  1PFJ A;  3AU4 A;  2KIG A;  2RGN B;  4YL8 A;  1KZG A;  4EKU A;  1WJ1 A;  3RCP A;  4K81 A;  1UPR A;  2D9X A;  3SO6 A;  3FM8 C;  4OT1 A;  1RJ2 A;  2RUK B;  4K2P A;  3M1I B;  3ULC A;  1V61 A;  3ULB A;  2COD A;  2RSG A;  1DDV A;  2COF A;  4DIX A;  1K5G B;  2XQN M;  3HQC A;  3PEG A;  5C79 A;  4GMX B;  3F0W A;  3ZDT A;  5EFX A;  3NWA A;  2L2I A;  3TO1 A;  2LKO A;  5D27 A;  1QQG A;  3QIJ A;  1UPQ A;  1X1G A;  1H4R A;  2Y8F A;  2Z14 A;  1J0W A;  5D3W A;  1FHX A;  3CIK A;  2H7E A;  3D8E A;  1SGH A;  3WA0 A;  1FGZ A;  2DX5 A;  4Z2N A;  2AL6 A;  2D4Q A;  2J0M A;  1LW3 A;  4A5K A;  1T77 A;  2D10 A;  3G9W A;  4HB2 B;  1NTY A;  1MPH A;  1FAO A;  2CRF A;  4PQ0 A;  1UNQ A;  2UZR A;  3CXB B;  2IYB A;  2CY5 A;  1K5D B;  5I2S A;  1OQN A;  4ZRJ A;  2DYN A;  1PLS A;  3X23 A;  4HAV B;  4HAU B;  1H10 A;  2HTH B;  1EVH A;  1V89 A;  2COC A;  1U5F A;  2K8E A;  1WJM A;  2K2J A;  2UVM A;  3KZ1 A;  2YSZ A;  4BBK A;  5D3X A;  1U27 A;  2W2X C;  4HB3 B;  4KVG B;  1V5U A;  4QJ4 B;  2J0K A;  3TFM A;  2H7D A;  2X18 A;  1P5T A;  2E2X A;  1X05 A;  2CAY A;  3P6A A;  2M14 A;  2COA A;  5L81 A;  4L1R A;  1WI1 A;  1J19 A;  2AEH A;  2EC1 A;  2BCJ A;  2P8V A;  4CYE A;  1AWE A;  2RNR B;  2W2W A;  3VOQ A;  1XX0 A;  4QJ5 B;  3V5W A;  3PVL A;  2NMB A;  2LOZ A;  1FGY A;  2Z13 A;  4WJ7 A;  4A6H A;  5JLJ B;  3PVU A;  2YT0 A;  1U29 A;  2EMT A;  2G35 A;  4KHB A;  4YON A;  2VSZ A;  2LOX A;  2OQB A;  4WSF A;  4F7H A;  3A8P A;  2KIE A;  2D9Z A;  3FSS A;  2ROZ B;  3KRW A;  2CY4 A;  2D11 A;  4CHJ A;  1DDW A;  5DI9 B;  1BTK A;  4A6F B;  3A8Q A;  1I2H A;  1MI1 A;  4OSN A;  1DBH A;  4F7G A;  4HAW B;  4GPT B;  4KHA A;  2P0D A;  4MT7 A;  2YS1 A;  3DCX A;  3PVW A;  5J3Q A;  2N23 A;  4KAX B;  4DXA B;  1FHW A;  5C16 A;  5C5B A;  4NY0 A;  1N3H A;  1OMW A;  4XWX A;  3AU5 A;  1M7R A;  3U12 A;  1BWN A;  1XR0 B;  2KGX B;  3TCA A;  1MIZ B;  1MKE A;  4C0A A;  4TYZ A;  3OHM B;  4KHO A;  4WVF B;  3T06 A;  1Q67 A;  3MPX A;  1XOD A;  1ZVR A;  1GC6 A;  1GG3 A;  1I7A A;  1XKE A;  2R09 A;  1DYN A;  2R0D A;  4B6H A;  1WGU A;  3LJU X;  4P7I A;  4TKN A;  5IRS A;  2YT2 A;  1XD4 A;  2I5C A;  4A6K A;  3NWD A;  2YF0 A; 
#chains in the Genus database with same CATH homology
 1DDM A;  1X11 A;  2J0J A;  3PSC A;  4HHV A;  2ELB A;  2V76 A;  3KRX A;  4HB4 B;  2MWN B;  2ROV A;  2I1J A;  3ODX A;  3ODO A;  2P0F A;  2RLO A;  5DHA B;  5D3Y A;  4NSW A;  1QC6 A;  2IFS A;  3HW2 B;  2Z0P A;  3UZT A;  4IFS A;  2D2Q A;  3BIN A;  4ZRI A;  1XCG A;  1MIX A;  1MK9 B;  3QBV B;  2DFK A;  2VRW B;  3U8Z A;  2LYD A;  5KCV A;  4ZRK A;  2MKR A;  4PNK A;  1ZC3 B;  1IRS A;  2I5F A;  1UNP A;  3SNH A;  2YT1 A;  2D9Y A;  2K2U A;  2DKQ A;  1UNR A;  1ZC4 B;  2MFQ A;  2HE7 A;  1X1F A;  1FOE A;  2QKM A;  2P0H A;  5JHH A;  4Y94 A;  1V5P A;  4MK0 A;  5J3T A;  1LB1 A;  2Q13 A;  5FI0 A;  1W1H A;  5DH9 B;  3DXC A;  2YS5 A;  3AJ4 A;  1ZM0 A;  4MY6 A;  5JP4 A;  1B55 A;  1ZSQ A;  5LOP B;  2I1K A;  1KI1 B;  3SUZ A;  1FB8 A;  1Z87 A;  4HDQ A;  2KUP A;  3MDB C;  3KY9 A;  1M7E A;  2GCL A;  3PZD A;  2YVC A;  1E5W A;  2ADZ A;  1TQZ A;  3N7C A;  1V88 A;  1X86 A;  2Y8G A;  2GS0 A;  4DX9 0;  3QWM A;  1EGX A;  2D9V A;  3SYX A;  2PZ1 A;  5HE2 A;  2QKL A;  2YRY A;  1W1D A;  2Y7B A;  2D9W A;  5CLQ B;  2EJ8 A;  5C6R A;  2DYQ A;  1EAZ A;  3O96 A;  4IAP A;  4K17 A;  1RRP B;  1V5M A;  2GCJ A;  4HB0 B;  1U5E A;  2LG1 A;  1NU2 A;  3VIA A;  4DBB A;  2KCJ A;  4D0N B;  3HK0 A;  3DXE A;  2N0Y A;  2OTX A;  2MDX A;  4CHM A;  3F5R A;  2DHK A;  4GN1 A;  1NI2 A;  1MAI A;  1PMS A;  3BJI A;  3PG7 A;  3A98 B;  2Z0Q A;  2Z0O A;  2DA0 A;  1U5G A;  1U2B A;  2EMS A;  2JP2 A;  3GYO A;  2L1C A;  4HAZ B;  3D8D A;  5GOW B;  4A6F A;  5HE3 A;  3WYF B;  3TW1 A;  1NTV A;  3D8F A;  5CLL B;  4HAX B;  1FHO A;  3ODW A;  2DX1 A;  3IVF A;  5KQ1 A;  5LON B;  4EJN A;  1BAK A;  5JHG A;  3TVV A;  4GXB A;  3NSU A;  1Y19 B;  4K2O A;  1WVH A;  2ELA A;  1MK7 B;  4GZU A;  4KHB B;  1WGQ A;  4IOY X;  5DHF B;  2LUL A;  5D3V A;  3GYP A;  1UEF A;  5J3Y A;  2DTC A;  1P6S A;  3P7Z A;  3FEH A;  3SV1 A;  3PP2 A;  2DLW A;  5KQ4 A;  1SHC A;  1AQC A;  4DX8 A;  2K00 A;  1DRO A;  1W1G A;  2M38 A;  3ML4 A;  3KSY A;  2J59 M;  3ZVR A;  2RVB B;  2GJY A;  4HAT B;  2DHI A;  4EMO A;  3OAN A;  2DKP A;  3DXD A;  2NZ8 B;  2W2X D;  5HE1 A;  1Y5O A;  5HE0 A;  5DIF B;  5C5B B;  1ISN A;  4HAY B;  5FI1 A;  1EF1 A;  1P3R A;  4Z2M B;  3U7D A;  2YS3 A;  1BTN A;  1TXD A;  4HDO A;  2VKI A;  1GC7 A;  2DHJ A;  1WG7 A;  1U5D A;  2DN6 A;  4F7U P;  4GMV A;  2ZPY A;  4L6E A;  1TJ6 A;  2UZS A;  4H8S A;  2FJL A;  1KZ7 A;  1OY2 A;  1PFJ A;  3AU4 A;  2RGN B;  4YL8 A;  1KZG A;  4EKU A;  1WJ1 A;  3RCP A;  4K81 A;  1UPR A;  2D9X A;  3SO6 A;  3FM8 C;  1RJ2 A;  2RUK B;  4K2P A;  3M1I B;  3ULC A;  1V61 A;  3ULB A;  2COD A;  2RSG A;  1DDV A;  2COF A;  1K5G B;  2XQN M;  3HQC A;  3PEG A;  5C79 A;  4GMX B;  3F0W A;  3ZDT A;  5EFX A;  2L2I A;  3TO1 A;  2LKO A;  5D27 A;  1QQG A;  3QIJ A;  1UPQ A;  1X1G A;  1H4R A;  2Y8F A;  1J0W A;  5D3W A;  1FHX A;  3CIK A;  2H7E A;  3D8E A;  1SGH A;  3WA0 A;  1FGZ A;  2DX5 A;  4Z2N A;  2AL6 A;  2D4Q A;  2J0M A;  1LW3 A;  4A5K A;  2D10 A;  3G9W A;  4HB2 B;  1NTY A;  1MPH A;  1FAO A;  2CRF A;  4PQ0 A;  1UNQ A;  2UZR A;  3CXB B;  2IYB A;  2CY5 A;  1K5D B;  1OQN A;  4ZRJ A;  2DYN A;  1PLS A;  3X23 A;  4HAV B;  4HAU B;  1H10 A;  2HTH B;  1EVH A;  1V89 A;  2COC A;  1U5F A;  1WJM A;  2K2J A;  2UVM A;  3KZ1 A;  2YSZ A;  4BBK A;  5D3X A;  1U27 A;  2W2X C;  4HB3 B;  4KVG B;  1V5U A;  2J0K A;  3TFM A;  2H7D A;  2X18 A;  1P5T A;  2E2X A;  1X05 A;  2CAY A;  3P6A A;  2M14 A;  2COA A;  5L81 A;  1WI1 A;  1J19 A;  2AEH A;  2EC1 A;  2BCJ A;  2P8V A;  4CYE A;  1AWE A;  2RNR B;  2W2W A;  3VOQ A;  1XX0 A;  3V5W A;  3PVL A;  2NMB A;  2LOZ A;  1FGY A;  4WJ7 A;  4A6H A;  5JLJ B;  3PVU A;  2YT0 A;  1U29 A;  2EMT A;  2G35 A;  4YON A;  2VSZ A;  2LOX A;  2OQB A;  4WSF A;  4F7H A;  3A8P A;  2D9Z A;  3FSS A;  2ROZ B;  3KRW A;  2CY4 A;  2D11 A;  4CHJ A;  1DDW A;  5DI9 B;  1BTK A;  4A6F B;  3A8Q A;  1I2H A;  1DBH A;  4F7G A;  4HAW B;  4GPT B;  4KHA A;  2P0D A;  4MT7 A;  2YS1 A;  3PVW A;  5J3Q A;  2N23 A;  4KAX B;  4DXA B;  1FHW A;  5C16 A;  5C5B A;  4NY0 A;  1N3H A;  1OMW A;  4XWX A;  3AU5 A;  1M7R A;  1BWN A;  1XR0 B;  2KGX B;  3TCA A;  1MIZ B;  1MKE A;  4C0A A;  4TYZ A;  4KHO A;  4WVF B;  3T06 A;  1Q67 A;  3MPX A;  1XOD A;  1ZVR A;  1GC6 A;  1GG3 A;  1I7A A;  1XKE A;  2R09 A;  1DYN A;  2R0D A;  4B6H A;  1WGU A;  3LJU X;  4P7I A;  4TKN A;  1XD4 A;  2I5C A;  4A6K A;  2YF0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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