5D3XA

Crystal structure of the p-rex1 ph domain with inositol-(1,3,4,5)-tetrakisphosphate bound
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
165
structure length
151
Chain Sequence
GEFEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKLGMERDAY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Lipid binding protein
molecule keywords Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac excha
total genus 46
structure length 151
sequence length 165
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-08-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 5d3xA00
4YONA 3AJ4A 1V5PA 1FAOA 2DYQA 2I1KA 4KHOA 2GCLA 2ELBA 2XQNM 1XR0B 1EAZA 1KZGA 3F5RA 2RUKB 1DYNA 2QKMA 4EKUA 1SHCA 4Z2NA 3NSUA 4PNKA 1V61A 1Y5OA 2V76A 3V5WA 2P0FA 1X1FA 2J0JA 4NY0A 4WVFB 4Z2MB 2DX1A 2Z0QA 3PG7A 4HAUB 3DXCA 5HE0A 2DHJA 2EMSA 1OMWA 1K5DB 2YT0A 4L6EA 1WI1A 2YSZA 3FM8C 3SNHA 1DDMA 3PEGA 2DLWA 3ODXA 3KY9A 3WYFB 2ELAA 2OTXA 1GG3A 2MDXA 1XCGA 5JHGA 5FI0A 4A6HA 2DFKA 4A6FA 1Q67A 1MK7B 2COCA 2LKOA 2KCJA 3RCPA 2YS1A 4XWXA 3UZTA 3P7ZA 4NSWA 1U5FA 4HAWB 1W1GA 2D10A 2RSGA 1H4RA 1W1DA 2NMBA 5D3XA 4KAXB 2LYDA 1NU2A 1UPRA 4KHAA 2NZ8B 1FGZA 2KUPA 3GYPA 2X18A 2MKRA 2DN6A 1IRSA 5LOPB 2CY5A 2COFA 2D9XA 1FHXA 4MY6A 2D11A 5DHFB 4B6HA 1XD4A 1V89A 2N23A 4TYZA 1DDWA 1MIXA 5HE1A 4HAZB 1M7EA 2P0HA 2YVCA 4DBBA 3IVFA 5C5BB 1MKEA 1FHWA 5J3QA 2CODA 2ZPYA 2RLOA 1QQGA 4PQ0A 2Z0OA 5JP4A 2J0KA 2L1CA 2YT1A 1DROA 1U29A 1FB8A 1LB1A 1UPQA 3HK0A 2UZRA 3ULBA 2D4QA 4DX8A 1KI1B 2RNRB 4EJNA 2J59M 3PVLA 4TKNA 3MDBC 3SV1A 2DX5A 5D3YA 3DXDA 2IYBA 2Y8FA 3HQCA 2I5CA 1ZC3B 3VOQA 1DDVA 2M38A 2OQBA 1RRPB 1SGHA 5EFXA 2MFQA 2HTHB 2Y7BA 2DHKA 1MK9B 4IAPA 2ROVA 3MPXA 4HHVA 1AQCA 1UEFA 1P3RA 1MAIA 1ZSQA 4IOYX 3D8FA 1M7RA 4BBKA 2R09A 2H7DA 3FEHA 2D2QA 4F7GA 3TO1A 4HDOA 1Y19B 4F7HA 2DKQA 4MK0A 5C5BA 3PVWA 1WJ1A 1NI2A 3ZDTA 2H7EA 1FHOA 5KCVA 2L2IA 3X23A 1EVHA 2D9VA 5CLLB 3VIAA 4C0AA 1I7AA 3AU4A 5DH9B 1UNPA 4HDQA 2DTCA 4HB4B 1UNRA 2W2XD 1PFJA 1QC6A 2UVMA 2W2WA 4HAYB 3D8EA 5JLJB 1U5GA 1NTYA 4HATB 1H10A 1EGXA 3ML4A 2QKLA 2Q13A 2YS3A 1WGUA 4K2OA 2HE7A 3A8PA 2MWNB 4ZRKA 2GS0A 2EC1A 4MT7A 2IFSA 4DX90 1EF1A 2D9ZA 2EJ8A 4ZRIA 4CHMA 1FOEA 1J19A 2KGXB 3LJUX 3A98B 2PZ1A 2RVBB 4HB0B 5D3WA 1Z87A 1DBHA 3KSYA 3TVVA 2JP2A 3KZ1A 5D27A 3PZDA 1WVHA 4D0NB 2DA0A 5J3TA 2K00A 1U27A 1XKEA 1WGQA 2BCJA 4GXBA 3BINA 3ULCA 4KVGB 3TW1A 2Z0PA 4KHBB 2W2XC 3U7DA 1ZC4B 5C79A 1BAKA 3O96A 2UZSA 2VSZA 5J3YA 5L81A 4H8SA 4HB2B 1PMSA 1V88A 3T06A 3F0WA 3KRWA 2ADZA 1FGYA 1NTVA 1OY2A 1AWEA 2DKPA 4GPTB 4ZRJA 2LOZA 2K2JA 5HE2A 3FSSA 2DHIA 4IFSA 1X1GA 4P7IA 2ROZB 1OQNA 3G9WA 4CHJA 5KQ1A 1K5GB 1TJ6A 2RGNB 3ODOA 4GN1A 4EMOA 2I5FA 5GOWB 1U2BA 1TQZA 1ZVRA 3ZVRA 4A5KA 3AU5A 2VKIA 5HE3A 4K17A 4F7UP 1X11A 3D8DA 3KRXA 2R0DA 3BJIA 2J0MA 4HB3B 3OANA 3CXBB 1V5UA 5DIFB 3PSCA 2EMTA 2N0YA 1E5WA 3SO6A 3SYXA 1X86A 4K2PA 2YF0A 5KQ4A 2Y8GA 1WG7A 3HW2B 1LW3A 1KZ7A 1BTKA 3DXEA 1U5EA 2CRFA 3GYOA 5JHHA 1X05A 1N3HA 2AEHA 4YL8A 4CYEA 4HAVB 4A6KA 1UNQA 2I1JA 1MIZB 2AL6A 3QIJA 1GC6A 3QBVB 4K81A 4A6FB 1BTNA 2COAA 3PP2A 2GJYA 3ODWA 3TCAA 4WSFA 3P6AA 2YS5A 2DYNA 1MPHA 2D9YA 1XODA 2LG1A 4GMXB 3CIKA 1WJMA 5LONB 2P8VA 4Y94A 2M14A 4HAXB 2VRWB 3TFMA 1I2HA 1XX0A 4DXAB 2GCJA 3N7CA 2D9WA 5D3VA 1RJ2A 4WJ7A 2G35A 2LOXA 1P6SA 1PLSA 5DHAB 2LULA 5C6RA 1P5TA 3SUZA 3U8ZA 5DI9B 3WA0A 5C16A 5CLQB 4GMVA 1B55A 5FI1A 2E2XA 4GZUA 3QWMA 1ZM0A 2K2UA 2CY4A 2P0DA 2YRYA 1TXDA 1BWNA 3M1IB 3PVUA 2CAYA 1GC7A 1V5MA 1J0WA 1W1HA 1ISNA 1U5DA 3A8QA 2FJLA
chains in the Genus database with same CATH superfamily
4YONA 3AJ4A 1V5PA 1FAOA 2DYQA 2I1KA 4KHOA 2ZKMX 2GCLA 2ELBA 2XQNM 1XR0B 1EAZA 1KZGA 3F5RA 2RUKB 1DYNA 2QKMA 4EKUA 1SHCA 4Z2NA 3NSUA 5IRSA 4PNKA 1V61A 1Y5OA 2V76A 3V5WA 2P0FA 1X1FA 2J0JA 4NY0A 4WVFB 4Z2MB 2DX1A 2Z0QA 3PG7A 4HAUB 3DXCA 5HE0A 2DHJA 3HIEA 2EMSA 1OMWA 1K5DB 2YT0A 4L6EA 1WI1A 2YSZA 3FM8C 3SNHA 1DDMA 3PEGA 2DLWA 3ODXA 4GOUA 3KY9A 3WYFB 2ELAA 2OTXA 1GG3A 2MDXA 1XCGA 5JHGA 5FI0A 4A6HA 2DFKA 4A6FA 1Q67A 1MK7B 2COCA 2LKOA 2KCJA 3RCPA 2YS1A 4XWXA 3UZTA 3P7ZA 4NSWA 2KIGA 1T77A 1U5FA 4HAWB 1W1GA 2D10A 2RSGA 1H4RA 1W1DA 2NMBA 4L1RA 5D3XA 5I2MA 4KAXB 2LYDA 1NU2A 1UPRA 4KHAA 2NZ8B 1FGZA 2KUPA 3GYPA 2X18A 2MKRA 2DN6A 1IRSA 5LOPB 3A58A 2CY5A 2COFA 2D9XA 1FHXA 4MY6A 2D11A 5DHFB 4B6HA 1XD4A 1V89A 2N23A 4TYZA 1DDWA 1MIXA 5HE1A 2P0HA 1M7EA 2YVCA 4HAZB 4DBBA 3IVFA 5C5BB 1MKEA 1FHWA 5J3QA 2CODA 2ZPYA 2RLOA 1QQGA 4PQ0A 2Z0OA 5JP4A 2J0KA 2L1CA 2YT1A 1DROA 1U29A 1FB8A 1LB1A 1UPQA 3HK0A 2UZRA 3ULBA 5M4YB 2D4QA 4DX8A 1KI1B 2RNRB 4EJNA 2J59M 3PVLA 4TKNA 3MDBC 3SV1A 2DX5A 5D3YA 2YT2A 2IYBA 3DXDA 2Y8FA 3HQCA 2I5CA 1ZC3B 2K8EA 4OT1A 3VOQA 1DDVA 2M38A 2OQBA 1RRPB 1SGHA 5EFXA 2MFQA 2HTHB 2Y7BA 2DHKA 1MK9B 4IAPA 2ROVA 3MPXA 4HHVA 1AQCA 1UEFA 1P3RA 1MAIA 1ZSQA 4IOYX 3D8FA 1M7RA 4BBKA 5I2SA 2R09A 2H7DA 3FEHA 2D2QA 4F7GA 3TO1A 5LG4B 4HDOA 1Y19B 4F7HA 4QJ4B 2DKQA 4MK0A 5C5BA 3PVWA 1WJ1A 1NI2A 3ZDTA 2H7EA 1FHOA 5KCVA 2L2IA 3X23A 1ZYIA 1EVHA 2D9VA 3B77A 5CLLB 3VIAA 4C0AA 1I7AA 2RRFA 3NWDA 1MI1A 2Z59A 3AU4A 5DH9B 1UNPA 4HDQA 2DTCA 3HSAA 4HB4B 1UNRA 2W2XD 1PFJA 1QC6A 2Z4DA 2UVMA 2W2WA 4HAYB 3D8EA 5JLJB 1U5GA 1NTYA 4HATB 4D6WA 1H10A 1EGXA 3NWAA 3ML4A 4QXAB 2QKLA 2Q13A 2YS3A 1WGUA 4K2OA 2HE7A 3A8PA 2KR0A 2MWNB 4ZRKA 4GNKB 2GS0A 2EC1A 4MT7A 2IFSA 4DX90 1EF1A 2D9ZA 2EJ8A 4ZRIA 4CHMA 1FOEA 1J19A 2KGXB 3LJUX 3A98B 2PZ1A 2RVBB 4HB0B 5D3WA 1Z87A 1DBHA 3KSYA 3TVVA 2JP2A 4QJ5B 3KZ1A 5D27A 3PZDA 1WVHA 4D0NB 2DA0A 5J3TA 2K00A 1U27A 1XKEA 1WGQA 2BCJA 4GXBA 3BINA 3ULCA 4KVGB 3TW1A 2Z0PA 4KHBB 2W2XC 3FVCA 3U7DA 1ZC4B 5C79A 1BAKA 3O96A 2UZSA 2VSZA 5J3YA 5L81A 4H8SA 4HB2B 1PMSA 1V88A 3T06A 3F0WA 3KRWA 2ADZA 1FGYA 1NTVA 1OY2A 1AWEA 2DKPA 4GPTB 4ZRJA 2LOZA 2K2JA 5HE2A 4KHBA 3FSSA 2DHIA 4IFSA 1X1GA 4P7IA 2ROZB 1OQNA 3G9WA 4CHJA 5KQ1A 1K5GB 1TJ6A 2RGNB 3ODOA 4GN1A 4EMOA 2I5FA 5GOWB 2Z14A 1U2BA 1TQZA 1ZVRA 3ZVRA 3NW8A 2R2YA 4A5KA 3AU5A 2VKIA 5HE3A 4K17A 4DIXA 4F7UP 1X11A 3D8DA 3KRXA 2R0DA 2KIEA 3BJIA 2J0MA 4HB3B 3OANA 3CXBB 1V5UA 5DIFB 3PSCA 2EMTA 2N0YA 1E5WA 3SO6A 3SYXA 1X86A 4HSIA 4K2PA 2YF0A 5KQ4A 2Y8GA 1WG7A 3HW2B 1LW3A 1KZ7A 1BTKA 3DXEA 1U5EA 2CRFA 3GYOA 5JHHA 1X05A 1N3HA 2AEHA 4YL8A 4CYEA 2NBVA 2FJUB 4HAVB 3U12A 4A6KA 1UNQA 2I1JA 1MIZB 2AL6A 3QIJA 1GC6A 3QBVB 4K81A 4A6FB 1BTNA 2COAA 3PP2A 2GJYA 2K49A 3NWFA 3ODWA 3TCAA 4WSFA 3P6AA 2YS5A 2DYNA 1MPHA 2D9YA 1XODA 2LG1A 2Z13A 4GMXB 3CIKA 1WJMA 5LONB 2P8VA 4Y94A 2M14A 4HAXB 2VRWB 3TFMA 3DCXA 4QJ3B 1I2HA 1XX0A 4OSNA 4DXAB 2GCJA 3N7CA 2D9WA 5D3VA 1RJ2A 4WJ7A 2G35A 2GUMA 2LOXA 2KUQA 1P6SA 1PLSA 5DHAB 2LULA 5C6RA 1P5TA 3SUZA 3U8ZA 4CSQA 5DI9B 3WA0A 5C16A 5CLQB 4GMVA 1B55A 5FI1A 2E2XA 4GZUA 3QWMA 1ZM0A 2K2UA 2CY4A 2P0DA 2YRYA 1TXDA 1BWNA 3M1IB 3PVUA 2CAYA 1GC7A 1V5MA 1J0WA 1W1HA 3OHMB 1ISNA 1U5DA 3A8QA 2FJLA
chains in the Genus database with same CATH topology
4YONA 3AJ4A 1V5PA 1FAOA 2DYQA 2I1KA 4KHOA 2GCLA 2ELBA 2XQNM 1XR0B 1EAZA 1KZGA 3F5RA 2RUKB 1DYNA 2QKMA 4EKUA 1SHCA 4Z2NA 3NSUA 4PNKA 1V61A 1Y5OA 2V76A 3V5WA 2P0FA 1X1FA 2J0JA 4NY0A 4WVFB 4Z2MB 2DX1A 2Z0QA 3PG7A 4HAUB 3DXCA 5HE0A 2DHJA 2EMSA 1OMWA 1K5DB 2YT0A 4L6EA 1WI1A 2YSZA 3FM8C 3SNHA 1DDMA 3PEGA 2DLWA 3ODXA 3KY9A 3WYFB 2ELAA 2OTXA 1GG3A 2MDXA 1XCGA 5JHGA 5FI0A 4A6HA 2DFKA 4A6FA 1Q67A 1MK7B 2COCA 2LKOA 2KCJA 3RCPA 2YS1A 4XWXA 3UZTA 3P7ZA 4NSWA 1U5FA 4HAWB 1W1GA 2D10A 2RSGA 1H4RA 1W1DA 2NMBA 5D3XA 4KAXB 2LYDA 1NU2A 1UPRA 4KHAA 2NZ8B 1FGZA 2KUPA 3GYPA 2X18A 2MKRA 2DN6A 1IRSA 5LOPB 2CY5A 2COFA 2D9XA 1FHXA 4MY6A 2D11A 5DHFB 4B6HA 1XD4A 1V89A 2N23A 4TYZA 1DDWA 1MIXA 5HE1A 4HAZB 1M7EA 2P0HA 2YVCA 4DBBA 3IVFA 5C5BB 1MKEA 1FHWA 5J3QA 2CODA 2ZPYA 2RLOA 1QQGA 4PQ0A 2Z0OA 5JP4A 2J0KA 2L1CA 2YT1A 1DROA 1U29A 1FB8A 1LB1A 1UPQA 3HK0A 2UZRA 3ULBA 2D4QA 4DX8A 1KI1B 2RNRB 4EJNA 2J59M 3PVLA 4TKNA 3MDBC 3SV1A 2DX5A 5D3YA 3DXDA 2IYBA 2Y8FA 3HQCA 2I5CA 1ZC3B 3VOQA 1DDVA 2M38A 2OQBA 1RRPB 1SGHA 5EFXA 2MFQA 2HTHB 2Y7BA 2DHKA 1MK9B 4IAPA 2ROVA 3MPXA 4HHVA 1AQCA 1UEFA 1P3RA 1MAIA 1ZSQA 4IOYX 3D8FA 1M7RA 4BBKA 2R09A 2H7DA 3FEHA 2D2QA 4F7GA 3TO1A 4HDOA 1Y19B 4F7HA 2DKQA 4MK0A 5C5BA 3PVWA 1WJ1A 1NI2A 3ZDTA 2H7EA 1FHOA 5KCVA 2L2IA 3X23A 1EVHA 2D9VA 5CLLB 3VIAA 4C0AA 1I7AA 3AU4A 5DH9B 1UNPA 4HDQA 2DTCA 4HB4B 1UNRA 2W2XD 1PFJA 1QC6A 2UVMA 2W2WA 4HAYB 3D8EA 5JLJB 1U5GA 1NTYA 4HATB 1H10A 1EGXA 3ML4A 2QKLA 2Q13A 2YS3A 1WGUA 4K2OA 2HE7A 3A8PA 2MWNB 4ZRKA 2GS0A 2EC1A 4MT7A 2IFSA 4DX90 1EF1A 2D9ZA 2EJ8A 4ZRIA 4CHMA 1FOEA 1J19A 2KGXB 3LJUX 3A98B 2PZ1A 2RVBB 4HB0B 5D3WA 1Z87A 1DBHA 3KSYA 3TVVA 2JP2A 3KZ1A 5D27A 3PZDA 1WVHA 4D0NB 2DA0A 5J3TA 2K00A 1U27A 1XKEA 1WGQA 2BCJA 4GXBA 3BINA 3ULCA 4KVGB 3TW1A 2Z0PA 4KHBB 2W2XC 3U7DA 1ZC4B 5C79A 1BAKA 3O96A 2UZSA 2VSZA 5J3YA 5L81A 4H8SA 4HB2B 1PMSA 1V88A 3T06A 3F0WA 3KRWA 2ADZA 1FGYA 1NTVA 1OY2A 1AWEA 2DKPA 4GPTB 4ZRJA 2LOZA 2K2JA 5HE2A 3FSSA 2DHIA 4IFSA 1X1GA 4P7IA 2ROZB 1OQNA 3G9WA 4CHJA 5KQ1A 1K5GB 1TJ6A 2RGNB 3ODOA 4GN1A 4EMOA 2I5FA 5GOWB 1U2BA 1TQZA 1ZVRA 3ZVRA 4A5KA 3AU5A 2VKIA 5HE3A 4K17A 4F7UP 1X11A 3D8DA 3KRXA 2R0DA 3BJIA 2J0MA 4HB3B 3OANA 3CXBB 1V5UA 5DIFB 3PSCA 2EMTA 2N0YA 1E5WA 3SO6A 3SYXA 1X86A 4K2PA 2YF0A 5KQ4A 2Y8GA 1WG7A 3HW2B 1LW3A 1KZ7A 1BTKA 3DXEA 1U5EA 2CRFA 3GYOA 5JHHA 1X05A 1N3HA 2AEHA 4YL8A 4CYEA 4HAVB 4A6KA 1UNQA 2I1JA 1MIZB 2AL6A 3QIJA 1GC6A 3QBVB 4K81A 4A6FB 1BTNA 2COAA 3PP2A 2GJYA 3ODWA 3TCAA 4WSFA 3P6AA 2YS5A 2DYNA 1MPHA 2D9YA 1XODA 2LG1A 4GMXB 3CIKA 1WJMA 5LONB 2P8VA 4Y94A 2M14A 4HAXB 2VRWB 3TFMA 1I2HA 1XX0A 4DXAB 2GCJA 3N7CA 2D9WA 5D3VA 1RJ2A 4WJ7A 2G35A 2LOXA 1P6SA 1PLSA 5DHAB 2LULA 5C6RA 1P5TA 3SUZA 3U8ZA 5DI9B 3WA0A 5C16A 5CLQB 4GMVA 1B55A 5FI1A 2E2XA 4GZUA 3QWMA 1ZM0A 2K2UA 2CY4A 2P0DA 2YRYA 1TXDA 1BWNA 3M1IB 3PVUA 2CAYA 1GC7A 1V5MA 1J0WA 1W1HA 1ISNA 1U5DA 3A8QA 2FJLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YON A;  3AJ4 A;  1V5P A;  1FAO A;  2DYQ A;  2I1K A;  4KHO A;  2GCL A;  2ELB A;  2XQN M;  1XR0 B;  1EAZ A;  1KZG A;  3F5R A;  2RUK B;  1DYN A;  2QKM A;  4EKU A;  1SHC A;  4Z2N A;  3NSU A;  4PNK A;  1V61 A;  1Y5O A;  2V76 A;  3V5W A;  2P0F A;  1X1F A;  2J0J A;  4NY0 A;  4WVF B;  4Z2M B;  2DX1 A;  2Z0Q A;  3PG7 A;  4HAU B;  3DXC A;  5HE0 A;  2DHJ A;  2EMS A;  1OMW A;  1K5D B;  2YT0 A;  4L6E A;  1WI1 A;  2YSZ A;  3FM8 C;  3SNH A;  1DDM A;  3PEG A;  2DLW A;  3ODX A;  3KY9 A;  3WYF B;  2ELA A;  2OTX A;  1GG3 A;  2MDX A;  1XCG A;  5JHG A;  5FI0 A;  4A6H A;  2DFK A;  4A6F A;  1Q67 A;  1MK7 B;  2COC A;  2LKO A;  2KCJ A;  3RCP A;  2YS1 A;  4XWX A;  3UZT A;  3P7Z A;  4NSW A;  1U5F A;  4HAW B;  1W1G A;  2D10 A;  2RSG A;  1H4R A;  1W1D A;  2NMB A;  5D3X A;  4KAX B;  2LYD A;  1NU2 A;  1UPR A;  4KHA A;  2NZ8 B;  1FGZ A;  2KUP A;  3GYP A;  2X18 A;  2MKR A;  2DN6 A;  1IRS A;  5LOP B;  2CY5 A;  2COF A;  2D9X A;  1FHX A;  4MY6 A;  2D11 A;  5DHF B;  4B6H A;  1XD4 A;  1V89 A;  2N23 A;  4TYZ A;  1DDW A;  1MIX A;  5HE1 A;  4HAZ B;  1M7E A;  2P0H A;  2YVC A;  4DBB A;  3IVF A;  5C5B B;  1MKE A;  1FHW A;  5J3Q A;  2COD A;  2ZPY A;  2RLO A;  1QQG A;  4PQ0 A;  2Z0O A;  5JP4 A;  2J0K A;  2L1C A;  2YT1 A;  1DRO A;  1U29 A;  1FB8 A;  1LB1 A;  1UPQ A;  3HK0 A;  2UZR A;  3ULB A;  2D4Q A;  4DX8 A;  1KI1 B;  2RNR B;  4EJN A;  2J59 M;  3PVL A;  4TKN A;  3MDB C;  3SV1 A;  2DX5 A;  5D3Y A;  3DXD A;  2IYB A;  2Y8F A;  3HQC A;  2I5C A;  1ZC3 B;  3VOQ A;  1DDV A;  2M38 A;  2OQB A;  1RRP B;  1SGH A;  5EFX A;  2MFQ A;  2HTH B;  2Y7B A;  2DHK A;  1MK9 B;  4IAP A;  2ROV A;  3MPX A;  4HHV A;  1AQC A;  1UEF A;  1P3R A;  1MAI A;  1ZSQ A;  4IOY X;  3D8F A;  1M7R A;  4BBK A;  2R09 A;  2H7D A;  3FEH A;  2D2Q A;  4F7G A;  3TO1 A;  4HDO A;  1Y19 B;  4F7H A;  2DKQ A;  4MK0 A;  5C5B A;  3PVW A;  1WJ1 A;  1NI2 A;  3ZDT A;  2H7E A;  1FHO A;  5KCV A;  2L2I A;  3X23 A;  1EVH A;  2D9V A;  5CLL B;  3VIA A;  4C0A A;  1I7A A;  3AU4 A;  5DH9 B;  1UNP A;  4HDQ A;  2DTC A;  4HB4 B;  1UNR A;  2W2X D;  1PFJ A;  1QC6 A;  2UVM A;  2W2W A;  4HAY B;  3D8E A;  5JLJ B;  1U5G A;  1NTY A;  4HAT B;  1H10 A;  1EGX A;  3ML4 A;  2QKL A;  2Q13 A;  2YS3 A;  1WGU A;  4K2O A;  2HE7 A;  3A8P A;  2MWN B;  4ZRK A;  2GS0 A;  2EC1 A;  4MT7 A;  2IFS A;  4DX9 0;  1EF1 A;  2D9Z A;  2EJ8 A;  4ZRI A;  4CHM A;  1FOE A;  1J19 A;  2KGX B;  3LJU X;  3A98 B;  2PZ1 A;  2RVB B;  4HB0 B;  5D3W A;  1Z87 A;  1DBH A;  3KSY A;  3TVV A;  2JP2 A;  3KZ1 A;  5D27 A;  3PZD A;  1WVH A;  4D0N B;  2DA0 A;  5J3T A;  2K00 A;  1U27 A;  1XKE A;  1WGQ A;  2BCJ A;  4GXB A;  3BIN A;  3ULC A;  4KVG B;  3TW1 A;  2Z0P A;  4KHB B;  2W2X C;  3U7D A;  1ZC4 B;  5C79 A;  1BAK A;  3O96 A;  2UZS A;  2VSZ A;  5J3Y A;  5L81 A;  4H8S A;  4HB2 B;  1PMS A;  1V88 A;  3T06 A;  3F0W A;  3KRW A;  2ADZ A;  1FGY A;  1NTV A;  1OY2 A;  1AWE A;  2DKP A;  4GPT B;  4ZRJ A;  2LOZ A;  2K2J A;  5HE2 A;  3FSS A;  2DHI A;  4IFS A;  1X1G A;  4P7I A;  2ROZ B;  1OQN A;  3G9W A;  4CHJ A;  5KQ1 A;  1K5G B;  1TJ6 A;  2RGN B;  3ODO A;  4GN1 A;  4EMO A;  2I5F A;  5GOW B;  1U2B A;  1TQZ A;  1ZVR A;  3ZVR A;  4A5K A;  3AU5 A;  2VKI A;  5HE3 A;  4K17 A;  4F7U P;  1X11 A;  3D8D A;  3KRX A;  2R0D A;  3BJI A;  2J0M A;  4HB3 B;  3OAN A;  3CXB B;  1V5U A;  5DIF B;  3PSC A;  2EMT A;  2N0Y A;  1E5W A;  3SO6 A;  3SYX A;  1X86 A;  4K2P A;  2YF0 A;  5KQ4 A;  2Y8G A;  1WG7 A;  3HW2 B;  1LW3 A;  1KZ7 A;  1BTK A;  3DXE A;  1U5E A;  2CRF A;  3GYO A;  5JHH A;  1X05 A;  1N3H A;  2AEH A;  4YL8 A;  4CYE A;  4HAV B;  4A6K A;  1UNQ A;  2I1J A;  1MIZ B;  2AL6 A;  3QIJ A;  1GC6 A;  3QBV B;  4K81 A;  4A6F B;  1BTN A;  2COA A;  3PP2 A;  2GJY A;  3ODW A;  3TCA A;  4WSF A;  3P6A A;  2YS5 A;  2DYN A;  1MPH A;  2D9Y A;  1XOD A;  2LG1 A;  4GMX B;  3CIK A;  1WJM A;  5LON B;  2P8V A;  4Y94 A;  2M14 A;  4HAX B;  2VRW B;  3TFM A;  1I2H A;  1XX0 A;  4DXA B;  2GCJ A;  3N7C A;  2D9W A;  5D3V A;  1RJ2 A;  4WJ7 A;  2G35 A;  2LOX A;  1P6S A;  1PLS A;  5DHA B;  2LUL A;  5C6R A;  1P5T A;  3SUZ A;  3U8Z A;  5DI9 B;  3WA0 A;  5C16 A;  5CLQ B;  4GMV A;  1B55 A;  5FI1 A;  2E2X A;  4GZU A;  3QWM A;  1ZM0 A;  2K2U A;  2CY4 A;  2P0D A;  2YRY A;  1TXD A;  1BWN A;  3M1I B;  3PVU A;  2CAY A;  1GC7 A;  1V5M A;  1J0W A;  1W1H A;  1ISN A;  1U5D A;  3A8Q A;  2FJL A; 
#chains in the Genus database with same CATH topology
 4YON A;  3AJ4 A;  1V5P A;  1FAO A;  2DYQ A;  2I1K A;  4KHO A;  2ZKM X;  2GCL A;  2ELB A;  2XQN M;  1XR0 B;  1EAZ A;  1KZG A;  3F5R A;  2RUK B;  1DYN A;  2QKM A;  4EKU A;  1SHC A;  4Z2N A;  3NSU A;  5IRS A;  4PNK A;  1V61 A;  1Y5O A;  2V76 A;  3V5W A;  2P0F A;  1X1F A;  2J0J A;  4NY0 A;  4WVF B;  4Z2M B;  2DX1 A;  2Z0Q A;  3PG7 A;  4HAU B;  3DXC A;  5HE0 A;  2DHJ A;  3HIE A;  2EMS A;  1OMW A;  1K5D B;  2YT0 A;  4L6E A;  1WI1 A;  2YSZ A;  3FM8 C;  3SNH A;  1DDM A;  3PEG A;  2DLW A;  3ODX A;  4GOU A;  3KY9 A;  3WYF B;  2ELA A;  2OTX A;  1GG3 A;  2MDX A;  1XCG A;  5JHG A;  5FI0 A;  4A6H A;  2DFK A;  4A6F A;  1Q67 A;  1MK7 B;  2COC A;  2LKO A;  2KCJ A;  3RCP A;  2YS1 A;  4XWX A;  3UZT A;  3P7Z A;  4NSW A;  2KIG A;  1T77 A;  1U5F A;  4HAW B;  1W1G A;  2D10 A;  2RSG A;  1H4R A;  1W1D A;  2NMB A;  4L1R A;  5D3X A;  5I2M A;  4KAX B;  2LYD A;  1NU2 A;  1UPR A;  4KHA A;  2NZ8 B;  1FGZ A;  2KUP A;  3GYP A;  2X18 A;  2MKR A;  2DN6 A;  1IRS A;  5LOP B;  3A58 A;  2CY5 A;  2COF A;  2D9X A;  1FHX A;  4MY6 A;  2D11 A;  5DHF B;  4B6H A;  1XD4 A;  1V89 A;  2N23 A;  4TYZ A;  1DDW A;  1MIX A;  5HE1 A;  2P0H A;  1M7E A;  2YVC A;  4HAZ B;  4DBB A;  3IVF A;  5C5B B;  1MKE A;  1FHW A;  5J3Q A;  2COD A;  2ZPY A;  2RLO A;  1QQG A;  4PQ0 A;  2Z0O A;  5JP4 A;  2J0K A;  2L1C A;  2YT1 A;  1DRO A;  1U29 A;  1FB8 A;  1LB1 A;  1UPQ A;  3HK0 A;  2UZR A;  3ULB A;  5M4Y B;  2D4Q A;  4DX8 A;  1KI1 B;  2RNR B;  4EJN A;  2J59 M;  3PVL A;  4TKN A;  3MDB C;  3SV1 A;  2DX5 A;  5D3Y A;  2YT2 A;  2IYB A;  3DXD A;  2Y8F A;  3HQC A;  2I5C A;  1ZC3 B;  2K8E A;  4OT1 A;  3VOQ A;  1DDV A;  2M38 A;  2OQB A;  1RRP B;  1SGH A;  5EFX A;  2MFQ A;  2HTH B;  2Y7B A;  2DHK A;  1MK9 B;  4IAP A;  2ROV A;  3MPX A;  4HHV A;  1AQC A;  1UEF A;  1P3R A;  1MAI A;  1ZSQ A;  4IOY X;  3D8F A;  1M7R A;  4BBK A;  5I2S A;  2R09 A;  2H7D A;  3FEH A;  2D2Q A;  4F7G A;  3TO1 A;  5LG4 B;  4HDO A;  1Y19 B;  4F7H A;  4QJ4 B;  2DKQ A;  4MK0 A;  5C5B A;  3PVW A;  1WJ1 A;  1NI2 A;  3ZDT A;  2H7E A;  1FHO A;  5KCV A;  2L2I A;  3X23 A;  1ZYI A;  1EVH A;  2D9V A;  3B77 A;  5CLL B;  3VIA A;  4C0A A;  1I7A A;  2RRF A;  3NWD A;  1MI1 A;  2Z59 A;  3AU4 A;  5DH9 B;  1UNP A;  4HDQ A;  2DTC A;  3HSA A;  4HB4 B;  1UNR A;  2W2X D;  1PFJ A;  1QC6 A;  2Z4D A;  2UVM A;  2W2W A;  4HAY B;  3D8E A;  5JLJ B;  1U5G A;  1NTY A;  4HAT B;  4D6W A;  1H10 A;  1EGX A;  3NWA A;  3ML4 A;  4QXA B;  2QKL A;  2Q13 A;  2YS3 A;  1WGU A;  4K2O A;  2HE7 A;  3A8P A;  2KR0 A;  2MWN B;  4ZRK A;  4GNK B;  2GS0 A;  2EC1 A;  4MT7 A;  2IFS A;  4DX9 0;  1EF1 A;  2D9Z A;  2EJ8 A;  4ZRI A;  4CHM A;  1FOE A;  1J19 A;  2KGX B;  3LJU X;  3A98 B;  2PZ1 A;  2RVB B;  4HB0 B;  5D3W A;  1Z87 A;  1DBH A;  3KSY A;  3TVV A;  2JP2 A;  4QJ5 B;  3KZ1 A;  5D27 A;  3PZD A;  1WVH A;  4D0N B;  2DA0 A;  5J3T A;  2K00 A;  1U27 A;  1XKE A;  1WGQ A;  2BCJ A;  4GXB A;  3BIN A;  3ULC A;  4KVG B;  3TW1 A;  2Z0P A;  4KHB B;  2W2X C;  3FVC A;  3U7D A;  1ZC4 B;  5C79 A;  1BAK A;  3O96 A;  2UZS A;  2VSZ A;  5J3Y A;  5L81 A;  4H8S A;  4HB2 B;  1PMS A;  1V88 A;  3T06 A;  3F0W A;  3KRW A;  2ADZ A;  1FGY A;  1NTV A;  1OY2 A;  1AWE A;  2DKP A;  4GPT B;  4ZRJ A;  2LOZ A;  2K2J A;  5HE2 A;  4KHB A;  3FSS A;  2DHI A;  4IFS A;  1X1G A;  4P7I A;  2ROZ B;  1OQN A;  3G9W A;  4CHJ A;  5KQ1 A;  1K5G B;  1TJ6 A;  2RGN B;  3ODO A;  4GN1 A;  4EMO A;  2I5F A;  5GOW B;  2Z14 A;  1U2B A;  1TQZ A;  1ZVR A;  3ZVR A;  3NW8 A;  2R2Y A;  4A5K A;  3AU5 A;  2VKI A;  5HE3 A;  4K17 A;  4DIX A;  4F7U P;  1X11 A;  3D8D A;  3KRX A;  2R0D A;  2KIE A;  3BJI A;  2J0M A;  4HB3 B;  3OAN A;  3CXB B;  1V5U A;  5DIF B;  3PSC A;  2EMT A;  2N0Y A;  1E5W A;  3SO6 A;  3SYX A;  1X86 A;  4HSI A;  4K2P A;  2YF0 A;  5KQ4 A;  2Y8G A;  1WG7 A;  3HW2 B;  1LW3 A;  1KZ7 A;  1BTK A;  3DXE A;  1U5E A;  2CRF A;  3GYO A;  5JHH A;  1X05 A;  1N3H A;  2AEH A;  4YL8 A;  4CYE A;  2NBV A;  2FJU B;  4HAV B;  3U12 A;  4A6K A;  1UNQ A;  2I1J A;  1MIZ B;  2AL6 A;  3QIJ A;  1GC6 A;  3QBV B;  4K81 A;  4A6F B;  1BTN A;  2COA A;  3PP2 A;  2GJY A;  2K49 A;  3NWF A;  3ODW A;  3TCA A;  4WSF A;  3P6A A;  2YS5 A;  2DYN A;  1MPH A;  2D9Y A;  1XOD A;  2LG1 A;  2Z13 A;  4GMX B;  3CIK A;  1WJM A;  5LON B;  2P8V A;  4Y94 A;  2M14 A;  4HAX B;  2VRW B;  3TFM A;  3DCX A;  4QJ3 B;  1I2H A;  1XX0 A;  4OSN A;  4DXA B;  2GCJ A;  3N7C A;  2D9W A;  5D3V A;  1RJ2 A;  4WJ7 A;  2G35 A;  2GUM A;  2LOX A;  2KUQ A;  1P6S A;  1PLS A;  5DHA B;  2LUL A;  5C6R A;  1P5T A;  3SUZ A;  3U8Z A;  4CSQ A;  5DI9 B;  3WA0 A;  5C16 A;  5CLQ B;  4GMV A;  1B55 A;  5FI1 A;  2E2X A;  4GZU A;  3QWM A;  1ZM0 A;  2K2U A;  2CY4 A;  2P0D A;  2YRY A;  1TXD A;  1BWN A;  3M1I B;  3PVU A;  2CAY A;  1GC7 A;  1V5M A;  1J0W A;  1W1H A;  3OHM B;  1ISN A;  1U5D A;  3A8Q A;  2FJL A; 
#chains in the Genus database with same CATH homology
 4YON A;  3AJ4 A;  1V5P A;  1FAO A;  2DYQ A;  2I1K A;  4KHO A;  2GCL A;  2ELB A;  2XQN M;  1XR0 B;  1EAZ A;  1KZG A;  3F5R A;  2RUK B;  1DYN A;  2QKM A;  4EKU A;  1SHC A;  4Z2N A;  3NSU A;  4PNK A;  1V61 A;  1Y5O A;  2V76 A;  3V5W A;  2P0F A;  1X1F A;  2J0J A;  4NY0 A;  4WVF B;  4Z2M B;  2DX1 A;  2Z0Q A;  3PG7 A;  4HAU B;  3DXC A;  5HE0 A;  2DHJ A;  2EMS A;  1OMW A;  1K5D B;  2YT0 A;  4L6E A;  1WI1 A;  2YSZ A;  3FM8 C;  3SNH A;  1DDM A;  3PEG A;  2DLW A;  3ODX A;  3KY9 A;  3WYF B;  2ELA A;  2OTX A;  1GG3 A;  2MDX A;  1XCG A;  5JHG A;  5FI0 A;  4A6H A;  2DFK A;  4A6F A;  1Q67 A;  1MK7 B;  2COC A;  2LKO A;  2KCJ A;  3RCP A;  2YS1 A;  4XWX A;  3UZT A;  3P7Z A;  4NSW A;  1U5F A;  4HAW B;  1W1G A;  2D10 A;  2RSG A;  1H4R A;  1W1D A;  2NMB A;  5D3X A;  4KAX B;  2LYD A;  1NU2 A;  1UPR A;  4KHA A;  2NZ8 B;  1FGZ A;  2KUP A;  3GYP A;  2X18 A;  2MKR A;  2DN6 A;  1IRS A;  5LOP B;  2CY5 A;  2COF A;  2D9X A;  1FHX A;  4MY6 A;  2D11 A;  5DHF B;  4B6H A;  1XD4 A;  1V89 A;  2N23 A;  4TYZ A;  1DDW A;  1MIX A;  5HE1 A;  4HAZ B;  1M7E A;  2P0H A;  2YVC A;  4DBB A;  3IVF A;  5C5B B;  1MKE A;  1FHW A;  5J3Q A;  2COD A;  2ZPY A;  2RLO A;  1QQG A;  4PQ0 A;  2Z0O A;  5JP4 A;  2J0K A;  2L1C A;  2YT1 A;  1DRO A;  1U29 A;  1FB8 A;  1LB1 A;  1UPQ A;  3HK0 A;  2UZR A;  3ULB A;  2D4Q A;  4DX8 A;  1KI1 B;  2RNR B;  4EJN A;  2J59 M;  3PVL A;  4TKN A;  3MDB C;  3SV1 A;  2DX5 A;  5D3Y A;  3DXD A;  2IYB A;  2Y8F A;  3HQC A;  2I5C A;  1ZC3 B;  3VOQ A;  1DDV A;  2M38 A;  2OQB A;  1RRP B;  1SGH A;  5EFX A;  2MFQ A;  2HTH B;  2Y7B A;  2DHK A;  1MK9 B;  4IAP A;  2ROV A;  3MPX A;  4HHV A;  1AQC A;  1UEF A;  1P3R A;  1MAI A;  1ZSQ A;  4IOY X;  3D8F A;  1M7R A;  4BBK A;  2R09 A;  2H7D A;  3FEH A;  2D2Q A;  4F7G A;  3TO1 A;  4HDO A;  1Y19 B;  4F7H A;  2DKQ A;  4MK0 A;  5C5B A;  3PVW A;  1WJ1 A;  1NI2 A;  3ZDT A;  2H7E A;  1FHO A;  5KCV A;  2L2I A;  3X23 A;  1EVH A;  2D9V A;  5CLL B;  3VIA A;  4C0A A;  1I7A A;  3AU4 A;  5DH9 B;  1UNP A;  4HDQ A;  2DTC A;  4HB4 B;  1UNR A;  2W2X D;  1PFJ A;  1QC6 A;  2UVM A;  2W2W A;  4HAY B;  3D8E A;  5JLJ B;  1U5G A;  1NTY A;  4HAT B;  1H10 A;  1EGX A;  3ML4 A;  2QKL A;  2Q13 A;  2YS3 A;  1WGU A;  4K2O A;  2HE7 A;  3A8P A;  2MWN B;  4ZRK A;  2GS0 A;  2EC1 A;  4MT7 A;  2IFS A;  4DX9 0;  1EF1 A;  2D9Z A;  2EJ8 A;  4ZRI A;  4CHM A;  1FOE A;  1J19 A;  2KGX B;  3LJU X;  3A98 B;  2PZ1 A;  2RVB B;  4HB0 B;  5D3W A;  1Z87 A;  1DBH A;  3KSY A;  3TVV A;  2JP2 A;  3KZ1 A;  5D27 A;  3PZD A;  1WVH A;  4D0N B;  2DA0 A;  5J3T A;  2K00 A;  1U27 A;  1XKE A;  1WGQ A;  2BCJ A;  4GXB A;  3BIN A;  3ULC A;  4KVG B;  3TW1 A;  2Z0P A;  4KHB B;  2W2X C;  3U7D A;  1ZC4 B;  5C79 A;  1BAK A;  3O96 A;  2UZS A;  2VSZ A;  5J3Y A;  5L81 A;  4H8S A;  4HB2 B;  1PMS A;  1V88 A;  3T06 A;  3F0W A;  3KRW A;  2ADZ A;  1FGY A;  1NTV A;  1OY2 A;  1AWE A;  2DKP A;  4GPT B;  4ZRJ A;  2LOZ A;  2K2J A;  5HE2 A;  3FSS A;  2DHI A;  4IFS A;  1X1G A;  4P7I A;  2ROZ B;  1OQN A;  3G9W A;  4CHJ A;  5KQ1 A;  1K5G B;  1TJ6 A;  2RGN B;  3ODO A;  4GN1 A;  4EMO A;  2I5F A;  5GOW B;  1U2B A;  1TQZ A;  1ZVR A;  3ZVR A;  4A5K A;  3AU5 A;  2VKI A;  5HE3 A;  4K17 A;  4F7U P;  1X11 A;  3D8D A;  3KRX A;  2R0D A;  3BJI A;  2J0M A;  4HB3 B;  3OAN A;  3CXB B;  1V5U A;  5DIF B;  3PSC A;  2EMT A;  2N0Y A;  1E5W A;  3SO6 A;  3SYX A;  1X86 A;  4K2P A;  2YF0 A;  5KQ4 A;  2Y8G A;  1WG7 A;  3HW2 B;  1LW3 A;  1KZ7 A;  1BTK A;  3DXE A;  1U5E A;  2CRF A;  3GYO A;  5JHH A;  1X05 A;  1N3H A;  2AEH A;  4YL8 A;  4CYE A;  4HAV B;  4A6K A;  1UNQ A;  2I1J A;  1MIZ B;  2AL6 A;  3QIJ A;  1GC6 A;  3QBV B;  4K81 A;  4A6F B;  1BTN A;  2COA A;  3PP2 A;  2GJY A;  3ODW A;  3TCA A;  4WSF A;  3P6A A;  2YS5 A;  2DYN A;  1MPH A;  2D9Y A;  1XOD A;  2LG1 A;  4GMX B;  3CIK A;  1WJM A;  5LON B;  2P8V A;  4Y94 A;  2M14 A;  4HAX B;  2VRW B;  3TFM A;  1I2H A;  1XX0 A;  4DXA B;  2GCJ A;  3N7C A;  2D9W A;  5D3V A;  1RJ2 A;  4WJ7 A;  2G35 A;  2LOX A;  1P6S A;  1PLS A;  5DHA B;  2LUL A;  5C6R A;  1P5T A;  3SUZ A;  3U8Z A;  5DI9 B;  3WA0 A;  5C16 A;  5CLQ B;  4GMV A;  1B55 A;  5FI1 A;  2E2X A;  4GZU A;  3QWM A;  1ZM0 A;  2K2U A;  2CY4 A;  2P0D A;  2YRY A;  1TXD A;  1BWN A;  3M1I B;  3PVU A;  2CAY A;  1GC7 A;  1V5M A;  1J0W A;  1W1H A;  1ISN A;  1U5D A;  3A8Q A;  2FJL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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