5D3XA

Crystal structure of the p-rex1 ph domain with inositol-(1,3,4,5)-tetrakisphosphate bound
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
165
structure length
151
Chain Sequence
GEFEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKLGMERDAY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac excha
publication title Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Lipid binding protein
total genus 46
structure length 151
sequence length 165
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-08-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 5d3xA00
4GZUA 3T06A 2RVBB 4K17A 3KZ1A 4GN1A 2DTCA 2UZRA 2I5FA 3QWMA 2J0MA 3UZTA 1N3HA 3PSCA 3RCPA 1X1FA 2YS3A 4K2PA 4KHBB 5KQ1A 3PVLA 3P7ZA 1UNQA 4WSFA 3PVWA 3U8ZA 1WJ1A 2MDXA 2Z0PA 3V5WA 4CYEA 4A6KA 4Y94A 1DDVA 5C5BB 2LG1A 5D3VA 5D27A 5HE3A 3D8EA 3ODWA 2KGXB 4TYZA 4NSWA 3DXEA 2HE7A 1EGXA 2UZSA 2J0KA 2DX5A 3SUZA 1EAZA 2MWNB 4CHJA 1GC7A 4HB2B 3CIKA 5D3XA 5KQ4A 2W2WA 5GOWB 2D9VA 1FAOA 1V89A 4KAXB 1WGUA 2GS0A 1FGYA 2YF0A 2JP2A 4KHOA 3GYOA 3PZDA 2P8VA 1FB8A 1MIXA 5DHAB 4KHAA 4PNKA 5LONB 1NU2A 1LB1A 1V88A 2D11A 2DKPA 2ELAA 3FEHA 1DDWA 2COCA 2I1KA 2DKQA 1ZM0A 5FI0A 2ADZA 1WG7A 5DI9B 1K5GB 2QKMA 4P7IA 3DXDA 1ZVRA 2GCLA 2DHIA 2P0HA 3CXBB 2J0JA 4YL8A 2CY4A 1KZGA 5JLJB 2AEHA 2LOXA 3ULCA 2W2XC 2M14A 2RNRB 2LOZA 5D3WA 1OY2A 3NSUA 2D10A 1LW3A 3A8QA 4A6FA 5JP4A 2XQNM 4HDOA 2RSGA 4K2OA 2RLOA 1U5GA 2CAYA 2V76A 4TKNA 2DYNA 1DYNA 2FJLA 1I2HA 3SO6A 4K81A 1WGQA 1TXDA 5HE1A 5D3YA 1FHWA 1GG3A 4HAYB 4IAPA 1J0WA 2COAA 1GC6A 1MIZB 2UVMA 4GXBA 1MK7B 2IFSA 4DX90 4Z2MB 1XCGA 2D9ZA 3KSYA 5LOPB 1H4RA 2Q13A 2YS1A 2N0YA 4A6HA 4XWXA 5JHHA 1E5WA 2VSZA 1EVHA 2P0DA 1NTVA 4A6FB 4F7UP 2NMBA 2E2XA 5HE2A 3BJIA 2LYDA 3QIJA 2I1JA 1SHCA 3P6AA 4HHVA 3MDBC 2P0FA 1DDMA 1W1GA 1FGZA 4MY6A 2CRFA 3HK0A 4HB0B 1W1HA 2YRYA 5C16A 3WA0A 3AU4A 1KI1B 4Z2NA 1XD4A 3AU5A 1ZSQA 1J19A 2CODA 5L81A 2Z0QA 1Q67A 1WVHA 5DIFB 3ODXA 1V5UA 4EKUA 1U5DA 2K2UA 2GCJA 3SYXA 1Z87A 2DYQA 3ODOA 4HAUB 4HAVB 4L6EA 2YVCA 3VOQA 5J3TA 4DBBA 3GYPA 5JHGA 1OQNA 4F7HA 2OQBA 3KY9A 5J3YA 1UNRA 3OANA 3ULBA 2K00A 3QBVB 5EFXA 4F7GA 3AJ4A 3IVFA 3WYFB 2YT1A 2D2QA 4MT7A 2L1CA 4YONA 1DROA 4HAZB 3U7DA 2X18A 1WI1A 2DFKA 1PLSA 3PG7A 4WVFB 2YSZA 1UEFA 1P5TA 4C0AA 2COFA 1ISNA 4HAWB 4D0NB 5FI1A 2NZ8B 3D8DA 1OMWA 2D9XA 3F0WA 2ROVA 2J59M 1MK9B 1FHOA 2HTHB 2YT0A 4HATB 4PQ0A 2IYBA 2PZ1A 1Y5OA 1PMSA 2MFQA 2RUKB 4IOYX 2BCJA 3PP2A 4DXAB 2EMTA 2DHKA 2ZPYA 1MKEA 2R0DA 2VKIA 2W2XD 2D4QA 1QC6A 3MPXA 1FHXA 4EJNA 3TO1A 2MKRA 1U29A 2Y8FA 2G35A 1V61A 1PFJA 4GMVA 4B6HA 3D8FA 1XKEA 3O96A 2CY5A 2DLWA 1P3RA 2LKOA 2AL6A 3M1IB 1UPQA 2Z0OA 3TFMA 4ZRIA 2OTXA 2ELBA 4H8SA 1U5FA 2K2JA 1X86A 3FM8C 3ML4A 2EJ8A 2Y8GA 1UPRA 1MPHA 1NI2A 1QQGA 4GPTB 1V5PA 1FOEA 2H7EA 5J3QA 1RRPB 2N23A 1KZ7A 2DN6A 1X05A 2LULA 1WJMA 3BINA 2GJYA 4BBKA 4EMOA 2D9WA 3LJUX 3PEGA 4NY0A 5KCVA 3VIAA 5DHFB 3KRWA 5CLLB 3F5RA 2D9YA 1AQCA 3HW2B 2VRWB 3TVVA 1BTNA 1H10A 3TW1A 1Y19B 3A98B 5C6RA 1UNPA 1BTKA 1M7EA 2DX1A 3X23A 1V5MA 2Y7BA 4KVGB 4MK0A 1IRSA 1U27A 4GMXB 1X1GA 5DH9B 2EC1A 1RJ2A 4IFSA 4HB4B 4ZRJA 2R09A 1NTYA 1TJ6A 1B55A 2H7DA 2RGNB 1MAIA 2QKLA 5CLQB 3A8PA 3G9WA 2DHJA 3KRXA 4WJ7A 4DX8A 1EF1A 2L2IA 3N7CA 3TCAA 1XX0A 1I7AA 1XODA 3SV1A 1BAKA 3FSSA 4ZRKA 1AWEA 2ROZB 5C79A 2M38A 1XR0B 3SNHA 1P6SA 4HDQA 2KUPA 1M7RA 3DXCA 1DBHA 1ZC4B 2DA0A 3ZVRA 1X11A 1U2BA 5C5BA 1U5EA 1ZC3B 1K5DB 4CHMA 4A5KA 1SGHA 3HQCA 3PVUA 1W1DA 4HAXB 3ZDTA 4HB3B 1TQZA 2KCJA 2EMSA 2YS5A 5HE0A 2I5CA 1BWNA
chains in the Genus database with same CATH superfamily
4GZUA 3T06A 4QJ5B 3A58A 2RVBB 4K17A 3KZ1A 4GN1A 2DTCA 4QJ3B 2UZRA 2I5FA 3QWMA 2J0MA 3UZTA 2RRFA 1N3HA 3PSCA 3RCPA 1X1FA 2YS3A 4K2PA 4KHBB 5KQ1A 3PVLA 3P7ZA 1UNQA 4WSFA 3PVWA 3U8ZA 1WJ1A 2MDXA 2Z0PA 3V5WA 4CYEA 4A6KA 4Y94A 1DDVA 5C5BB 4OSNA 2LG1A 5D3VA 5D27A 5HE3A 3D8EA 3ODWA 2KGXB 4TYZA 4NSWA 3DXEA 2HE7A 1EGXA 2UZSA 2J0KA 2DX5A 3SUZA 1EAZA 2MWNB 4CHJA 1GC7A 4HB2B 3CIKA 5D3XA 5KQ4A 2W2WA 5GOWB 2D9VA 4GNKB 1FAOA 1V89A 4KAXB 1WGUA 2GS0A 2R2YA 1FGYA 2YF0A 2JP2A 4KHOA 3GYOA 3PZDA 2P8VA 1FB8A 1MIXA 5DHAB 4KHAA 4PNKA 5LONB 1NU2A 1LB1A 1V88A 2D11A 2DKPA 2ELAA 3FEHA 1DDWA 2COCA 2I1KA 2DKQA 2Z59A 1ZM0A 5FI0A 2ADZA 2KIEA 1WG7A 5DI9B 1K5GB 2QKMA 4P7IA 3DXDA 2KUQA 1ZVRA 2GCLA 2DHIA 2P0HA 3CXBB 2J0JA 4YL8A 2CY4A 1KZGA 5JLJB 2AEHA 2LOXA 3ULCA 2W2XC 2M14A 2RNRB 2LOZA 5D3WA 1OY2A 3NSUA 2D10A 4QXAB 1LW3A 3A8QA 4A6FA 5JP4A 2K8EA 2XQNM 4HDOA 2RSGA 4K2OA 2RLOA 1U5GA 2CAYA 2V76A 4TKNA 2DYNA 1DYNA 2FJLA 1I2HA 3FVCA 3SO6A 4K81A 1WGQA 1TXDA 3NWAA 5HE1A 5D3YA 1FHWA 1GG3A 4HAYB 4IAPA 1J0WA 2COAA 1GC6A 1MIZB 2UVMA 4GXBA 2Z13A 1MK7B 2IFSA 4DX90 4Z2MB 1XCGA 2D9ZA 3KSYA 5LOPB 1H4RA 2Q13A 2YS1A 2N0YA 4A6HA 4XWXA 5JHHA 1E5WA 2VSZA 2YT2A 1EVHA 2P0DA 1NTVA 4A6FB 4F7UP 2NMBA 2E2XA 5HE2A 3BJIA 2LYDA 3QIJA 2I1JA 1SHCA 3P6AA 4HHVA 3MDBC 2P0FA 1DDMA 1W1GA 1T77A 1FGZA 4MY6A 2CRFA 3HK0A 4CSQA 4HB0B 1W1HA 2YRYA 5C16A 3WA0A 3AU4A 1KI1B 4D6WA 1XD4A 4Z2NA 3AU5A 1ZSQA 1J19A 2CODA 4DIXA 2Z0QA 5L81A 1Q67A 1WVHA 5DIFB 3ODXA 1V5UA 4EKUA 1U5DA 2K2UA 3NWFA 3NW8A 2GCJA 3SYXA 1Z87A 2DYQA 3ODOA 4HAUB 4HAVB 4L6EA 2YVCA 3VOQA 5J3TA 1ZYIA 4DBBA 3GYPA 5M4YB 5JHGA 1OQNA 4F7HA 2OQBA 3KY9A 5J3YA 1UNRA 3OANA 3ULBA 2K00A 3QBVB 5EFXA 4F7GA 3AJ4A 3IVFA 3WYFB 2YT1A 4GOUA 2D2QA 4MT7A 2L1CA 4YONA 1DROA 4HAZB 2KR0A 3U7DA 2X18A 1WI1A 2DFKA 1PLSA 3PG7A 4WVFB 2YSZA 1UEFA 1P5TA 4C0AA 2COFA 1ISNA 4HAWB 4D0NB 5FI1A 2GUMA 2NZ8B 3D8DA 1OMWA 2D9XA 3F0WA 5LG4B 2ROVA 2J59M 1MK9B 1FHOA 2HTHB 2YT0A 4HATB 4PQ0A 2IYBA 2PZ1A 1Y5OA 1PMSA 2MFQA 2RUKB 4IOYX 5I2SA 2BCJA 4L1RA 3PP2A 3B77A 4DXAB 2EMTA 2FJUB 2DHKA 2ZPYA 1MKEA 2R0DA 2VKIA 2W2XD 2D4QA 2KIGA 1QC6A 3MPXA 1FHXA 4EJNA 3TO1A 2MKRA 1U29A 2Y8FA 3NWDA 2G35A 1V61A 1PFJA 4GMVA 4B6HA 3D8FA 1XKEA 1MI1A 3O96A 2CY5A 2DLWA 1P3RA 2LKOA 2AL6A 3M1IB 1UPQA 2Z0OA 3TFMA 4ZRIA 2OTXA 2ELBA 4H8SA 1U5FA 2Z4DA 4QJ4B 2K2JA 1X86A 3FM8C 5I2MA 3ML4A 2EJ8A 2Y8GA 1UPRA 1MPHA 1NI2A 1QQGA 4GPTB 1V5PA 1FOEA 4OT1A 2H7EA 5J3QA 1RRPB 2N23A 1KZ7A 2DN6A 1X05A 2LULA 1WJMA 3BINA 2GJYA 4BBKA 4EMOA 2D9WA 3LJUX 3PEGA 4NY0A 5KCVA 5IRSA 2K49A 3VIAA 5DHFB 3KRWA 5CLLB 3F5RA 2D9YA 1AQCA 3HW2B 2VRWB 3TVVA 1BTNA 3OHMB 1H10A 3TW1A 3HSAA 1Y19B 3A98B 5C6RA 1UNPA 1BTKA 1M7EA 2DX1A 3X23A 1V5MA 2Y7BA 4KVGB 4MK0A 3HIEA 1IRSA 1U27A 4GMXB 1X1GA 5DH9B 2EC1A 2ZKMX 1RJ2A 4IFSA 4HB4B 4ZRJA 2R09A 1NTYA 1TJ6A 1B55A 2H7DA 2RGNB 4HSIA 1MAIA 2NBVA 2QKLA 5CLQB 3A8PA 3G9WA 2DHJA 3KRXA 4WJ7A 4DX8A 1EF1A 2L2IA 2Z14A 3N7CA 3TCAA 1XX0A 1I7AA 1XODA 3SV1A 1BAKA 3FSSA 4KHBA 4ZRKA 1AWEA 2ROZB 5C79A 2M38A 1XR0B 3SNHA 1P6SA 4HDQA 2KUPA 1M7RA 3DXCA 3U12A 1DBHA 1ZC4B 2DA0A 3ZVRA 1X11A 3DCXA 1U2BA 5C5BA 1U5EA 1ZC3B 1K5DB 4CHMA 4A5KA 1SGHA 3HQCA 3PVUA 1W1DA 4HAXB 3ZDTA 4HB3B 1TQZA 2KCJA 2EMSA 2YS5A 5HE0A 2I5CA 1BWNA
chains in the Genus database with same CATH topology
4GZUA 3T06A 2RVBB 4K17A 3KZ1A 4GN1A 2DTCA 2UZRA 2I5FA 3QWMA 2J0MA 3UZTA 1N3HA 3PSCA 3RCPA 1X1FA 2YS3A 4K2PA 4KHBB 5KQ1A 3PVLA 3P7ZA 1UNQA 4WSFA 3PVWA 3U8ZA 1WJ1A 2MDXA 2Z0PA 3V5WA 4CYEA 4A6KA 4Y94A 1DDVA 5C5BB 2LG1A 5D3VA 5D27A 5HE3A 3D8EA 3ODWA 2KGXB 4TYZA 4NSWA 3DXEA 2HE7A 1EGXA 2UZSA 2J0KA 2DX5A 3SUZA 1EAZA 2MWNB 4CHJA 1GC7A 4HB2B 3CIKA 5D3XA 5KQ4A 2W2WA 5GOWB 2D9VA 1FAOA 1V89A 4KAXB 1WGUA 2GS0A 1FGYA 2YF0A 2JP2A 4KHOA 3GYOA 3PZDA 2P8VA 1FB8A 1MIXA 5DHAB 4KHAA 4PNKA 5LONB 1NU2A 1LB1A 1V88A 2D11A 2DKPA 2ELAA 3FEHA 1DDWA 2COCA 2I1KA 2DKQA 1ZM0A 5FI0A 2ADZA 1WG7A 5DI9B 1K5GB 2QKMA 4P7IA 3DXDA 1ZVRA 2GCLA 2DHIA 2P0HA 3CXBB 2J0JA 4YL8A 2CY4A 1KZGA 5JLJB 2AEHA 2LOXA 3ULCA 2W2XC 2M14A 2RNRB 2LOZA 5D3WA 1OY2A 3NSUA 2D10A 1LW3A 3A8QA 4A6FA 5JP4A 2XQNM 4HDOA 2RSGA 4K2OA 2RLOA 1U5GA 2CAYA 2V76A 4TKNA 2DYNA 1DYNA 2FJLA 1I2HA 3SO6A 4K81A 1WGQA 1TXDA 5HE1A 5D3YA 1FHWA 1GG3A 4HAYB 4IAPA 1J0WA 2COAA 1GC6A 1MIZB 2UVMA 4GXBA 1MK7B 2IFSA 4DX90 4Z2MB 1XCGA 2D9ZA 3KSYA 5LOPB 1H4RA 2Q13A 2YS1A 2N0YA 4A6HA 4XWXA 5JHHA 1E5WA 2VSZA 1EVHA 2P0DA 1NTVA 4A6FB 4F7UP 2NMBA 2E2XA 5HE2A 3BJIA 2LYDA 3QIJA 2I1JA 1SHCA 3P6AA 4HHVA 3MDBC 2P0FA 1DDMA 1W1GA 1FGZA 4MY6A 2CRFA 3HK0A 4HB0B 1W1HA 2YRYA 5C16A 3WA0A 3AU4A 1KI1B 4Z2NA 1XD4A 3AU5A 1ZSQA 1J19A 2CODA 5L81A 2Z0QA 1Q67A 1WVHA 5DIFB 3ODXA 1V5UA 4EKUA 1U5DA 2K2UA 2GCJA 3SYXA 1Z87A 2DYQA 3ODOA 4HAUB 4HAVB 4L6EA 2YVCA 3VOQA 5J3TA 4DBBA 3GYPA 5JHGA 1OQNA 4F7HA 2OQBA 3KY9A 5J3YA 1UNRA 3OANA 3ULBA 2K00A 3QBVB 5EFXA 4F7GA 3AJ4A 3IVFA 3WYFB 2YT1A 2D2QA 4MT7A 2L1CA 4YONA 1DROA 4HAZB 3U7DA 2X18A 1WI1A 2DFKA 1PLSA 3PG7A 4WVFB 2YSZA 1UEFA 1P5TA 4C0AA 2COFA 1ISNA 4HAWB 4D0NB 5FI1A 2NZ8B 3D8DA 1OMWA 2D9XA 3F0WA 2ROVA 2J59M 1MK9B 1FHOA 2HTHB 2YT0A 4HATB 4PQ0A 2IYBA 2PZ1A 1Y5OA 1PMSA 2MFQA 2RUKB 4IOYX 2BCJA 3PP2A 4DXAB 2EMTA 2DHKA 2ZPYA 1MKEA 2R0DA 2VKIA 2W2XD 2D4QA 1QC6A 3MPXA 1FHXA 4EJNA 3TO1A 2MKRA 1U29A 2Y8FA 2G35A 1V61A 1PFJA 4GMVA 4B6HA 3D8FA 1XKEA 3O96A 2CY5A 2DLWA 1P3RA 2LKOA 2AL6A 3M1IB 1UPQA 2Z0OA 3TFMA 4ZRIA 2OTXA 2ELBA 4H8SA 1U5FA 2K2JA 1X86A 3FM8C 3ML4A 2EJ8A 2Y8GA 1UPRA 1MPHA 1NI2A 1QQGA 4GPTB 1V5PA 1FOEA 2H7EA 5J3QA 1RRPB 2N23A 1KZ7A 2DN6A 1X05A 2LULA 1WJMA 3BINA 2GJYA 4BBKA 4EMOA 2D9WA 3LJUX 3PEGA 4NY0A 5KCVA 3VIAA 5DHFB 3KRWA 5CLLB 3F5RA 2D9YA 1AQCA 3HW2B 2VRWB 3TVVA 1BTNA 1H10A 3TW1A 1Y19B 3A98B 5C6RA 1UNPA 1BTKA 1M7EA 2DX1A 3X23A 1V5MA 2Y7BA 4KVGB 4MK0A 1IRSA 1U27A 4GMXB 1X1GA 5DH9B 2EC1A 1RJ2A 4IFSA 4HB4B 4ZRJA 2R09A 1NTYA 1TJ6A 1B55A 2H7DA 2RGNB 1MAIA 2QKLA 5CLQB 3A8PA 3G9WA 2DHJA 3KRXA 4WJ7A 4DX8A 1EF1A 2L2IA 3N7CA 3TCAA 1XX0A 1I7AA 1XODA 3SV1A 1BAKA 3FSSA 4ZRKA 1AWEA 2ROZB 5C79A 2M38A 1XR0B 3SNHA 1P6SA 4HDQA 2KUPA 1M7RA 3DXCA 1DBHA 1ZC4B 2DA0A 3ZVRA 1X11A 1U2BA 5C5BA 1U5EA 1ZC3B 1K5DB 4CHMA 4A5KA 1SGHA 3HQCA 3PVUA 1W1DA 4HAXB 3ZDTA 4HB3B 1TQZA 2KCJA 2EMSA 2YS5A 5HE0A 2I5CA 1BWNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GZU A;  3T06 A;  2RVB B;  4K17 A;  3KZ1 A;  4GN1 A;  2DTC A;  2UZR A;  2I5F A;  3QWM A;  2J0M A;  3UZT A;  1N3H A;  3PSC A;  3RCP A;  1X1F A;  2YS3 A;  4K2P A;  4KHB B;  5KQ1 A;  3PVL A;  3P7Z A;  1UNQ A;  4WSF A;  3PVW A;  3U8Z A;  1WJ1 A;  2MDX A;  2Z0P A;  3V5W A;  4CYE A;  4A6K A;  4Y94 A;  1DDV A;  5C5B B;  2LG1 A;  5D3V A;  5D27 A;  5HE3 A;  3D8E A;  3ODW A;  2KGX B;  4TYZ A;  4NSW A;  3DXE A;  2HE7 A;  1EGX A;  2UZS A;  2J0K A;  2DX5 A;  3SUZ A;  1EAZ A;  2MWN B;  4CHJ A;  1GC7 A;  4HB2 B;  3CIK A;  5D3X A;  5KQ4 A;  2W2W A;  5GOW B;  2D9V A;  1FAO A;  1V89 A;  4KAX B;  1WGU A;  2GS0 A;  1FGY A;  2YF0 A;  2JP2 A;  4KHO A;  3GYO A;  3PZD A;  2P8V A;  1FB8 A;  1MIX A;  5DHA B;  4KHA A;  4PNK A;  5LON B;  1NU2 A;  1LB1 A;  1V88 A;  2D11 A;  2DKP A;  2ELA A;  3FEH A;  1DDW A;  2COC A;  2I1K A;  2DKQ A;  1ZM0 A;  5FI0 A;  2ADZ A;  1WG7 A;  5DI9 B;  1K5G B;  2QKM A;  4P7I A;  3DXD A;  1ZVR A;  2GCL A;  2DHI A;  2P0H A;  3CXB B;  2J0J A;  4YL8 A;  2CY4 A;  1KZG A;  5JLJ B;  2AEH A;  2LOX A;  3ULC A;  2W2X C;  2M14 A;  2RNR B;  2LOZ A;  5D3W A;  1OY2 A;  3NSU A;  2D10 A;  1LW3 A;  3A8Q A;  4A6F A;  5JP4 A;  2XQN M;  4HDO A;  2RSG A;  4K2O A;  2RLO A;  1U5G A;  2CAY A;  2V76 A;  4TKN A;  2DYN A;  1DYN A;  2FJL A;  1I2H A;  3SO6 A;  4K81 A;  1WGQ A;  1TXD A;  5HE1 A;  5D3Y A;  1FHW A;  1GG3 A;  4HAY B;  4IAP A;  1J0W A;  2COA A;  1GC6 A;  1MIZ B;  2UVM A;  4GXB A;  1MK7 B;  2IFS A;  4DX9 0;  4Z2M B;  1XCG A;  2D9Z A;  3KSY A;  5LOP B;  1H4R A;  2Q13 A;  2YS1 A;  2N0Y A;  4A6H A;  4XWX A;  5JHH A;  1E5W A;  2VSZ A;  1EVH A;  2P0D A;  1NTV A;  4A6F B;  4F7U P;  2NMB A;  2E2X A;  5HE2 A;  3BJI A;  2LYD A;  3QIJ A;  2I1J A;  1SHC A;  3P6A A;  4HHV A;  3MDB C;  2P0F A;  1DDM A;  1W1G A;  1FGZ A;  4MY6 A;  2CRF A;  3HK0 A;  4HB0 B;  1W1H A;  2YRY A;  5C16 A;  3WA0 A;  3AU4 A;  1KI1 B;  4Z2N A;  1XD4 A;  3AU5 A;  1ZSQ A;  1J19 A;  2COD A;  5L81 A;  2Z0Q A;  1Q67 A;  1WVH A;  5DIF B;  3ODX A;  1V5U A;  4EKU A;  1U5D A;  2K2U A;  2GCJ A;  3SYX A;  1Z87 A;  2DYQ A;  3ODO A;  4HAU B;  4HAV B;  4L6E A;  2YVC A;  3VOQ A;  5J3T A;  4DBB A;  3GYP A;  5JHG A;  1OQN A;  4F7H A;  2OQB A;  3KY9 A;  5J3Y A;  1UNR A;  3OAN A;  3ULB A;  2K00 A;  3QBV B;  5EFX A;  4F7G A;  3AJ4 A;  3IVF A;  3WYF B;  2YT1 A;  2D2Q A;  4MT7 A;  2L1C A;  4YON A;  1DRO A;  4HAZ B;  3U7D A;  2X18 A;  1WI1 A;  2DFK A;  1PLS A;  3PG7 A;  4WVF B;  2YSZ A;  1UEF A;  1P5T A;  4C0A A;  2COF A;  1ISN A;  4HAW B;  4D0N B;  5FI1 A;  2NZ8 B;  3D8D A;  1OMW A;  2D9X A;  3F0W A;  2ROV A;  2J59 M;  1MK9 B;  1FHO A;  2HTH B;  2YT0 A;  4HAT B;  4PQ0 A;  2IYB A;  2PZ1 A;  1Y5O A;  1PMS A;  2MFQ A;  2RUK B;  4IOY X;  2BCJ A;  3PP2 A;  4DXA B;  2EMT A;  2DHK A;  2ZPY A;  1MKE A;  2R0D A;  2VKI A;  2W2X D;  2D4Q A;  1QC6 A;  3MPX A;  1FHX A;  4EJN A;  3TO1 A;  2MKR A;  1U29 A;  2Y8F A;  2G35 A;  1V61 A;  1PFJ A;  4GMV A;  4B6H A;  3D8F A;  1XKE A;  3O96 A;  2CY5 A;  2DLW A;  1P3R A;  2LKO A;  2AL6 A;  3M1I B;  1UPQ A;  2Z0O A;  3TFM A;  4ZRI A;  2OTX A;  2ELB A;  4H8S A;  1U5F A;  2K2J A;  1X86 A;  3FM8 C;  3ML4 A;  2EJ8 A;  2Y8G A;  1UPR A;  1MPH A;  1NI2 A;  1QQG A;  4GPT B;  1V5P A;  1FOE A;  2H7E A;  5J3Q A;  1RRP B;  2N23 A;  1KZ7 A;  2DN6 A;  1X05 A;  2LUL A;  1WJM A;  3BIN A;  2GJY A;  4BBK A;  4EMO A;  2D9W A;  3LJU X;  3PEG A;  4NY0 A;  5KCV A;  3VIA A;  5DHF B;  3KRW A;  5CLL B;  3F5R A;  2D9Y A;  1AQC A;  3HW2 B;  2VRW B;  3TVV A;  1BTN A;  1H10 A;  3TW1 A;  1Y19 B;  3A98 B;  5C6R A;  1UNP A;  1BTK A;  1M7E A;  2DX1 A;  3X23 A;  1V5M A;  2Y7B A;  4KVG B;  4MK0 A;  1IRS A;  1U27 A;  4GMX B;  1X1G A;  5DH9 B;  2EC1 A;  1RJ2 A;  4IFS A;  4HB4 B;  4ZRJ A;  2R09 A;  1NTY A;  1TJ6 A;  1B55 A;  2H7D A;  2RGN B;  1MAI A;  2QKL A;  5CLQ B;  3A8P A;  3G9W A;  2DHJ A;  3KRX A;  4WJ7 A;  4DX8 A;  1EF1 A;  2L2I A;  3N7C A;  3TCA A;  1XX0 A;  1I7A A;  1XOD A;  3SV1 A;  1BAK A;  3FSS A;  4ZRK A;  1AWE A;  2ROZ B;  5C79 A;  2M38 A;  1XR0 B;  3SNH A;  1P6S A;  4HDQ A;  2KUP A;  1M7R A;  3DXC A;  1DBH A;  1ZC4 B;  2DA0 A;  3ZVR A;  1X11 A;  1U2B A;  5C5B A;  1U5E A;  1ZC3 B;  1K5D B;  4CHM A;  4A5K A;  1SGH A;  3HQC A;  3PVU A;  1W1D A;  4HAX B;  3ZDT A;  4HB3 B;  1TQZ A;  2KCJ A;  2EMS A;  2YS5 A;  5HE0 A;  2I5C A;  1BWN A; 
#chains in the Genus database with same CATH topology
 4GZU A;  3T06 A;  4QJ5 B;  3A58 A;  2RVB B;  4K17 A;  3KZ1 A;  4GN1 A;  2DTC A;  4QJ3 B;  2UZR A;  2I5F A;  3QWM A;  2J0M A;  3UZT A;  2RRF A;  1N3H A;  3PSC A;  3RCP A;  1X1F A;  2YS3 A;  4K2P A;  4KHB B;  5KQ1 A;  3PVL A;  3P7Z A;  1UNQ A;  4WSF A;  3PVW A;  3U8Z A;  1WJ1 A;  2MDX A;  2Z0P A;  3V5W A;  4CYE A;  4A6K A;  4Y94 A;  1DDV A;  5C5B B;  4OSN A;  2LG1 A;  5D3V A;  5D27 A;  5HE3 A;  3D8E A;  3ODW A;  2KGX B;  4TYZ A;  4NSW A;  3DXE A;  2HE7 A;  1EGX A;  2UZS A;  2J0K A;  2DX5 A;  3SUZ A;  1EAZ A;  2MWN B;  4CHJ A;  1GC7 A;  4HB2 B;  3CIK A;  5D3X A;  5KQ4 A;  2W2W A;  5GOW B;  2D9V A;  4GNK B;  1FAO A;  1V89 A;  4KAX B;  1WGU A;  2GS0 A;  2R2Y A;  1FGY A;  2YF0 A;  2JP2 A;  4KHO A;  3GYO A;  3PZD A;  2P8V A;  1FB8 A;  1MIX A;  5DHA B;  4KHA A;  4PNK A;  5LON B;  1NU2 A;  1LB1 A;  1V88 A;  2D11 A;  2DKP A;  2ELA A;  3FEH A;  1DDW A;  2COC A;  2I1K A;  2DKQ A;  2Z59 A;  1ZM0 A;  5FI0 A;  2ADZ A;  2KIE A;  1WG7 A;  5DI9 B;  1K5G B;  2QKM A;  4P7I A;  3DXD A;  2KUQ A;  1ZVR A;  2GCL A;  2DHI A;  2P0H A;  3CXB B;  2J0J A;  4YL8 A;  2CY4 A;  1KZG A;  5JLJ B;  2AEH A;  2LOX A;  3ULC A;  2W2X C;  2M14 A;  2RNR B;  2LOZ A;  5D3W A;  1OY2 A;  3NSU A;  2D10 A;  4QXA B;  1LW3 A;  3A8Q A;  4A6F A;  5JP4 A;  2K8E A;  2XQN M;  4HDO A;  2RSG A;  4K2O A;  2RLO A;  1U5G A;  2CAY A;  2V76 A;  4TKN A;  2DYN A;  1DYN A;  2FJL A;  1I2H A;  3FVC A;  3SO6 A;  4K81 A;  1WGQ A;  1TXD A;  3NWA A;  5HE1 A;  5D3Y A;  1FHW A;  1GG3 A;  4HAY B;  4IAP A;  1J0W A;  2COA A;  1GC6 A;  1MIZ B;  2UVM A;  4GXB A;  2Z13 A;  1MK7 B;  2IFS A;  4DX9 0;  4Z2M B;  1XCG A;  2D9Z A;  3KSY A;  5LOP B;  1H4R A;  2Q13 A;  2YS1 A;  2N0Y A;  4A6H A;  4XWX A;  5JHH A;  1E5W A;  2VSZ A;  2YT2 A;  1EVH A;  2P0D A;  1NTV A;  4A6F B;  4F7U P;  2NMB A;  2E2X A;  5HE2 A;  3BJI A;  2LYD A;  3QIJ A;  2I1J A;  1SHC A;  3P6A A;  4HHV A;  3MDB C;  2P0F A;  1DDM A;  1W1G A;  1T77 A;  1FGZ A;  4MY6 A;  2CRF A;  3HK0 A;  4CSQ A;  4HB0 B;  1W1H A;  2YRY A;  5C16 A;  3WA0 A;  3AU4 A;  1KI1 B;  4D6W A;  1XD4 A;  4Z2N A;  3AU5 A;  1ZSQ A;  1J19 A;  2COD A;  4DIX A;  2Z0Q A;  5L81 A;  1Q67 A;  1WVH A;  5DIF B;  3ODX A;  1V5U A;  4EKU A;  1U5D A;  2K2U A;  3NWF A;  3NW8 A;  2GCJ A;  3SYX A;  1Z87 A;  2DYQ A;  3ODO A;  4HAU B;  4HAV B;  4L6E A;  2YVC A;  3VOQ A;  5J3T A;  1ZYI A;  4DBB A;  3GYP A;  5M4Y B;  5JHG A;  1OQN A;  4F7H A;  2OQB A;  3KY9 A;  5J3Y A;  1UNR A;  3OAN A;  3ULB A;  2K00 A;  3QBV B;  5EFX A;  4F7G A;  3AJ4 A;  3IVF A;  3WYF B;  2YT1 A;  4GOU A;  2D2Q A;  4MT7 A;  2L1C A;  4YON A;  1DRO A;  4HAZ B;  2KR0 A;  3U7D A;  2X18 A;  1WI1 A;  2DFK A;  1PLS A;  3PG7 A;  4WVF B;  2YSZ A;  1UEF A;  1P5T A;  4C0A A;  2COF A;  1ISN A;  4HAW B;  4D0N B;  5FI1 A;  2GUM A;  2NZ8 B;  3D8D A;  1OMW A;  2D9X A;  3F0W A;  5LG4 B;  2ROV A;  2J59 M;  1MK9 B;  1FHO A;  2HTH B;  2YT0 A;  4HAT B;  4PQ0 A;  2IYB A;  2PZ1 A;  1Y5O A;  1PMS A;  2MFQ A;  2RUK B;  4IOY X;  5I2S A;  2BCJ A;  4L1R A;  3PP2 A;  3B77 A;  4DXA B;  2EMT A;  2FJU B;  2DHK A;  2ZPY A;  1MKE A;  2R0D A;  2VKI A;  2W2X D;  2D4Q A;  2KIG A;  1QC6 A;  3MPX A;  1FHX A;  4EJN A;  3TO1 A;  2MKR A;  1U29 A;  2Y8F A;  3NWD A;  2G35 A;  1V61 A;  1PFJ A;  4GMV A;  4B6H A;  3D8F A;  1XKE A;  1MI1 A;  3O96 A;  2CY5 A;  2DLW A;  1P3R A;  2LKO A;  2AL6 A;  3M1I B;  1UPQ A;  2Z0O A;  3TFM A;  4ZRI A;  2OTX A;  2ELB A;  4H8S A;  1U5F A;  2Z4D A;  4QJ4 B;  2K2J A;  1X86 A;  3FM8 C;  5I2M A;  3ML4 A;  2EJ8 A;  2Y8G A;  1UPR A;  1MPH A;  1NI2 A;  1QQG A;  4GPT B;  1V5P A;  1FOE A;  4OT1 A;  2H7E A;  5J3Q A;  1RRP B;  2N23 A;  1KZ7 A;  2DN6 A;  1X05 A;  2LUL A;  1WJM A;  3BIN A;  2GJY A;  4BBK A;  4EMO A;  2D9W A;  3LJU X;  3PEG A;  4NY0 A;  5KCV A;  5IRS A;  2K49 A;  3VIA A;  5DHF B;  3KRW A;  5CLL B;  3F5R A;  2D9Y A;  1AQC A;  3HW2 B;  2VRW B;  3TVV A;  1BTN A;  3OHM B;  1H10 A;  3TW1 A;  3HSA A;  1Y19 B;  3A98 B;  5C6R A;  1UNP A;  1BTK A;  1M7E A;  2DX1 A;  3X23 A;  1V5M A;  2Y7B A;  4KVG B;  4MK0 A;  3HIE A;  1IRS A;  1U27 A;  4GMX B;  1X1G A;  5DH9 B;  2EC1 A;  2ZKM X;  1RJ2 A;  4IFS A;  4HB4 B;  4ZRJ A;  2R09 A;  1NTY A;  1TJ6 A;  1B55 A;  2H7D A;  2RGN B;  4HSI A;  1MAI A;  2NBV A;  2QKL A;  5CLQ B;  3A8P A;  3G9W A;  2DHJ A;  3KRX A;  4WJ7 A;  4DX8 A;  1EF1 A;  2L2I A;  2Z14 A;  3N7C A;  3TCA A;  1XX0 A;  1I7A A;  1XOD A;  3SV1 A;  1BAK A;  3FSS A;  4KHB A;  4ZRK A;  1AWE A;  2ROZ B;  5C79 A;  2M38 A;  1XR0 B;  3SNH A;  1P6S A;  4HDQ A;  2KUP A;  1M7R A;  3DXC A;  3U12 A;  1DBH A;  1ZC4 B;  2DA0 A;  3ZVR A;  1X11 A;  3DCX A;  1U2B A;  5C5B A;  1U5E A;  1ZC3 B;  1K5D B;  4CHM A;  4A5K A;  1SGH A;  3HQC A;  3PVU A;  1W1D A;  4HAX B;  3ZDT A;  4HB3 B;  1TQZ A;  2KCJ A;  2EMS A;  2YS5 A;  5HE0 A;  2I5C A;  1BWN A; 
#chains in the Genus database with same CATH homology
 4GZU A;  3T06 A;  2RVB B;  4K17 A;  3KZ1 A;  4GN1 A;  2DTC A;  2UZR A;  2I5F A;  3QWM A;  2J0M A;  3UZT A;  1N3H A;  3PSC A;  3RCP A;  1X1F A;  2YS3 A;  4K2P A;  4KHB B;  5KQ1 A;  3PVL A;  3P7Z A;  1UNQ A;  4WSF A;  3PVW A;  3U8Z A;  1WJ1 A;  2MDX A;  2Z0P A;  3V5W A;  4CYE A;  4A6K A;  4Y94 A;  1DDV A;  5C5B B;  2LG1 A;  5D3V A;  5D27 A;  5HE3 A;  3D8E A;  3ODW A;  2KGX B;  4TYZ A;  4NSW A;  3DXE A;  2HE7 A;  1EGX A;  2UZS A;  2J0K A;  2DX5 A;  3SUZ A;  1EAZ A;  2MWN B;  4CHJ A;  1GC7 A;  4HB2 B;  3CIK A;  5D3X A;  5KQ4 A;  2W2W A;  5GOW B;  2D9V A;  1FAO A;  1V89 A;  4KAX B;  1WGU A;  2GS0 A;  1FGY A;  2YF0 A;  2JP2 A;  4KHO A;  3GYO A;  3PZD A;  2P8V A;  1FB8 A;  1MIX A;  5DHA B;  4KHA A;  4PNK A;  5LON B;  1NU2 A;  1LB1 A;  1V88 A;  2D11 A;  2DKP A;  2ELA A;  3FEH A;  1DDW A;  2COC A;  2I1K A;  2DKQ A;  1ZM0 A;  5FI0 A;  2ADZ A;  1WG7 A;  5DI9 B;  1K5G B;  2QKM A;  4P7I A;  3DXD A;  1ZVR A;  2GCL A;  2DHI A;  2P0H A;  3CXB B;  2J0J A;  4YL8 A;  2CY4 A;  1KZG A;  5JLJ B;  2AEH A;  2LOX A;  3ULC A;  2W2X C;  2M14 A;  2RNR B;  2LOZ A;  5D3W A;  1OY2 A;  3NSU A;  2D10 A;  1LW3 A;  3A8Q A;  4A6F A;  5JP4 A;  2XQN M;  4HDO A;  2RSG A;  4K2O A;  2RLO A;  1U5G A;  2CAY A;  2V76 A;  4TKN A;  2DYN A;  1DYN A;  2FJL A;  1I2H A;  3SO6 A;  4K81 A;  1WGQ A;  1TXD A;  5HE1 A;  5D3Y A;  1FHW A;  1GG3 A;  4HAY B;  4IAP A;  1J0W A;  2COA A;  1GC6 A;  1MIZ B;  2UVM A;  4GXB A;  1MK7 B;  2IFS A;  4DX9 0;  4Z2M B;  1XCG A;  2D9Z A;  3KSY A;  5LOP B;  1H4R A;  2Q13 A;  2YS1 A;  2N0Y A;  4A6H A;  4XWX A;  5JHH A;  1E5W A;  2VSZ A;  1EVH A;  2P0D A;  1NTV A;  4A6F B;  4F7U P;  2NMB A;  2E2X A;  5HE2 A;  3BJI A;  2LYD A;  3QIJ A;  2I1J A;  1SHC A;  3P6A A;  4HHV A;  3MDB C;  2P0F A;  1DDM A;  1W1G A;  1FGZ A;  4MY6 A;  2CRF A;  3HK0 A;  4HB0 B;  1W1H A;  2YRY A;  5C16 A;  3WA0 A;  3AU4 A;  1KI1 B;  4Z2N A;  1XD4 A;  3AU5 A;  1ZSQ A;  1J19 A;  2COD A;  5L81 A;  2Z0Q A;  1Q67 A;  1WVH A;  5DIF B;  3ODX A;  1V5U A;  4EKU A;  1U5D A;  2K2U A;  2GCJ A;  3SYX A;  1Z87 A;  2DYQ A;  3ODO A;  4HAU B;  4HAV B;  4L6E A;  2YVC A;  3VOQ A;  5J3T A;  4DBB A;  3GYP A;  5JHG A;  1OQN A;  4F7H A;  2OQB A;  3KY9 A;  5J3Y A;  1UNR A;  3OAN A;  3ULB A;  2K00 A;  3QBV B;  5EFX A;  4F7G A;  3AJ4 A;  3IVF A;  3WYF B;  2YT1 A;  2D2Q A;  4MT7 A;  2L1C A;  4YON A;  1DRO A;  4HAZ B;  3U7D A;  2X18 A;  1WI1 A;  2DFK A;  1PLS A;  3PG7 A;  4WVF B;  2YSZ A;  1UEF A;  1P5T A;  4C0A A;  2COF A;  1ISN A;  4HAW B;  4D0N B;  5FI1 A;  2NZ8 B;  3D8D A;  1OMW A;  2D9X A;  3F0W A;  2ROV A;  2J59 M;  1MK9 B;  1FHO A;  2HTH B;  2YT0 A;  4HAT B;  4PQ0 A;  2IYB A;  2PZ1 A;  1Y5O A;  1PMS A;  2MFQ A;  2RUK B;  4IOY X;  2BCJ A;  3PP2 A;  4DXA B;  2EMT A;  2DHK A;  2ZPY A;  1MKE A;  2R0D A;  2VKI A;  2W2X D;  2D4Q A;  1QC6 A;  3MPX A;  1FHX A;  4EJN A;  3TO1 A;  2MKR A;  1U29 A;  2Y8F A;  2G35 A;  1V61 A;  1PFJ A;  4GMV A;  4B6H A;  3D8F A;  1XKE A;  3O96 A;  2CY5 A;  2DLW A;  1P3R A;  2LKO A;  2AL6 A;  3M1I B;  1UPQ A;  2Z0O A;  3TFM A;  4ZRI A;  2OTX A;  2ELB A;  4H8S A;  1U5F A;  2K2J A;  1X86 A;  3FM8 C;  3ML4 A;  2EJ8 A;  2Y8G A;  1UPR A;  1MPH A;  1NI2 A;  1QQG A;  4GPT B;  1V5P A;  1FOE A;  2H7E A;  5J3Q A;  1RRP B;  2N23 A;  1KZ7 A;  2DN6 A;  1X05 A;  2LUL A;  1WJM A;  3BIN A;  2GJY A;  4BBK A;  4EMO A;  2D9W A;  3LJU X;  3PEG A;  4NY0 A;  5KCV A;  3VIA A;  5DHF B;  3KRW A;  5CLL B;  3F5R A;  2D9Y A;  1AQC A;  3HW2 B;  2VRW B;  3TVV A;  1BTN A;  1H10 A;  3TW1 A;  1Y19 B;  3A98 B;  5C6R A;  1UNP A;  1BTK A;  1M7E A;  2DX1 A;  3X23 A;  1V5M A;  2Y7B A;  4KVG B;  4MK0 A;  1IRS A;  1U27 A;  4GMX B;  1X1G A;  5DH9 B;  2EC1 A;  1RJ2 A;  4IFS A;  4HB4 B;  4ZRJ A;  2R09 A;  1NTY A;  1TJ6 A;  1B55 A;  2H7D A;  2RGN B;  1MAI A;  2QKL A;  5CLQ B;  3A8P A;  3G9W A;  2DHJ A;  3KRX A;  4WJ7 A;  4DX8 A;  1EF1 A;  2L2I A;  3N7C A;  3TCA A;  1XX0 A;  1I7A A;  1XOD A;  3SV1 A;  1BAK A;  3FSS A;  4ZRK A;  1AWE A;  2ROZ B;  5C79 A;  2M38 A;  1XR0 B;  3SNH A;  1P6S A;  4HDQ A;  2KUP A;  1M7R A;  3DXC A;  1DBH A;  1ZC4 B;  2DA0 A;  3ZVR A;  1X11 A;  1U2B A;  5C5B A;  1U5E A;  1ZC3 B;  1K5D B;  4CHM A;  4A5K A;  1SGH A;  3HQC A;  3PVU A;  1W1D A;  4HAX B;  3ZDT A;  4HB3 B;  1TQZ A;  2KCJ A;  2EMS A;  2YS5 A;  5HE0 A;  2I5C A;  1BWN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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