5D3XA

Crystal structure of the p-rex1 ph domain with inositol-(1,3,4,5)-tetrakisphosphate bound
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
165
structure length
151
Chain Sequence
b'GEFEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKLGMERDAY'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac excha
publication title Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Lipid binding protein
total genus 46
structure length 151
sequence length 165
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-08-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 5d3xA00
4HB2B 4MY6A 4A6FA 3UZTA 4TYZA 3BINA 2M14A 4F7GA 4HB3B 3ODXA 1V61A 2LULA 4H8SA 2X18A 4YL8A 1FHXA 2EJ8A 2D9WA 2AEHA 3WYFB 3F5RA 1ZVRA 2DYNA 3SYXA 3ULBA 1PLSA 1E5WA 4HHVA 2E2XA 2D4QA 2RNRB 4HATB 2N23A 4NSWA 2YSZA 1MIXA 3F0WA 1FOEA 4GZUA 2DYQA 2CODA 3LJUX 4GMVA 4A6HA 1ZSQA 2L1CA 2QKLA 1FB8A 1H10A 3M1IB 1UPQA 1V88A 2P0FA 3D8DA 2GCLA 2D11A 3NSUA 2RSGA 3PVLA 1EF1A 2EMTA 2I1KA 4EKUA 1X86A 2YT0A 1WG7A 4DXAB 1FGZA 1BWNA 1DDVA 2MFQA 2GCJA 3HQCA 1MAIA 3O96A 2Y7BA 3DXEA 2HE7A 4MT7A 2XQNM 1EVHA 3D8FA 2D2QA 4K2OA 2YRYA 2DHIA 4B6HA 1V5MA 3VIAA 1UNPA 2D9YA 3A8PA 4K81A 3TFMA 1XCGA 2K2JA 2MKRA 5JHGA 5C79A 3AU4A 3PSCA 5HE0A 2P0DA 2ROZB 4KAXB 3TO1A 3PEGA 1LB1A 3P7ZA 3PP2A 1BTNA 4D0NB 1WGQA 1QC6A 5HE1A 2IYBA 3DXDA 1U5EA 1W1GA 3HW2B 5DI9B 2YS5A 2YF0A 2R0DA 1FHWA 5D3VA 3CXBB 1N3HA 1X1GA 1XX0A 2LYDA 4GMXB 4K2PA 2ZPYA 3QBVB 2OQBA 2COFA 3HK0A 4BBKA 5JLJB 2COAA 3KZ1A 3U8ZA 2KCJA 2NMBA 4C0AA 5KCVA 2ADZA 5D3YA 4Z2MB 1V5PA 3ZVRA 5C5BA 2GJYA 1AWEA 1UNQA 5DHAB 4ZRJA 2FJLA 2L2IA 1BAKA 4HAXB 4KHAA 5HE2A 2RGNB 1GG3A 2J0JA 3ZDTA 5D3XA 3PVUA 2DHJA 5EFXA 5L81A 1FAOA 1WVHA 5KQ1A 2CRFA 2Q13A 1J19A 4ZRIA 3SNHA 2W2XC 4TKNA 1DYNA 4HAZB 1V89A 2GS0A 3GYPA 1B55A 5JHHA 1P6SA 2DKPA 2EC1A 4F7HA 4PNKA 1M7RA 3A8QA 3QIJA 2ELAA 4DX90 5D27A 2K00A 4IFSA 4A6FB 2MWNB 2DX5A 3ML4A 2PZ1A 2IFSA 4GPTB 4YONA 5D3WA 1ZC4B 2Y8FA 4CHMA 2HTHB 1LW3A 3SV1A 4Y94A 4ZRKA 3KSYA 5FI1A 5JP4A 1MIZB 2Z0OA 4GXBA 1AQCA 1WI1A 1U5DA 3BJIA 5KQ4A 2AL6A 1NTYA 2DN6A 3QWMA 2UZSA 1XODA 2Z0PA 5C16A 1FGYA 1RJ2A 2J0MA 2H7EA 1XKEA 1DDMA 3RCPA 2D9ZA 3IVFA 1U29A 2DHKA 4WJ7A 1P3RA 1W1DA 2I1JA 4A5KA 1U5GA 4K17A 1I2HA 4HDOA 1K5GB 1EGXA 4CYEA 4A6KA 2P0HA 2CY5A 4HAUB 2QKMA 2Y8GA 3A98B 1XR0B 1NTVA 2MDXA 5FI0A 1Q67A 1DDWA 3DXCA 2LOZA 4MK0A 2D9VA 2Z0QA 1J0WA 3D8EA 4KHOA 1PMSA 3PZDA 4DX8A 3PVWA 1GC7A 4XWXA 1OY2A 1FHOA 2ROVA 1MKEA 1SGHA 3PG7A 2UVMA 5GOWB 3U7DA 2DX1A 3V5WA 4WVFB 1UNRA 1U5FA 2J59M 2COCA 4KHBB 1WJ1A 2YT1A 2OTXA 2RVBB 4HAVB 3ULCA 3FM8C 2ELBA 3GYOA 5J3YA 3OANA 1GC6A 4HDQA 3MDBC 1U27A 1TJ6A 4Z2NA 3KY9A 3TVVA 1P5TA 1WGUA 2VKIA 3WA0A 2I5CA 5C5BB 2DFKA 4CHJA 5LOPB 3SO6A 1Y5OA 1X1FA 1SHCA 3TCAA 4WSFA 1W1HA 1V5UA 2LKOA 4HB4B 3AJ4A 1X11A 3X23A 3G9WA 4NY0A 3KRWA 1IRSA 1I7AA 1DBHA 3VOQA 1K5DB 1RRPB 1NI2A 2JP2A 1M7EA 2V76A 5LONB 2D10A 2CY4A 2KUPA 2UZRA 5CLQB 2RUKB 2DKQA 4DBBA 3SUZA 2CAYA 1BTKA 1UPRA 4KVGB 1OQNA 3ODOA 2D9XA 1KZGA 2W2XD 4EMOA 4PQ0A 4P7IA 1DROA 5DH9B 2R09A 5J3QA 3KRXA 2K2UA 1X05A 2NZ8B 1ZC3B 2BCJA 1TXDA 3TW1A 3FEHA 1H4RA 3P6AA 2N0YA 1KI1B 1U2BA 4F7UP 1XD4A 2YS3A 3N7CA 1OMWA 3MPXA 3FSSA 2G35A 2W2WA 1PFJA 4HB0B 4GN1A 1MPHA 2EMSA 4IOYX 1KZ7A 2M38A 5J3TA 4EJNA 1MK9B 2VRWB 2DA0A 2J0KA 2LOXA 4HAWB 2DLWA 5DHFB 1MK7B 5DIFB 1Z87A 4IAPA 2KGXB 2YS1A 2P8VA 1EAZA 2LG1A 5CLLB 2H7DA 1QQGA 1WJMA 1UEFA 2YVCA 1Y19B 3ODWA 5C6RA 1TQZA 5HE3A 2VSZA 1NU2A 3CIKA 2I5FA 2DTCA 1ZM0A 3T06A 3AU5A 1ISNA 2RLOA 4L6EA 4HAYB
chains in the Genus database with same CATH superfamily
2Z4DA 4HB2B 4MY6A 2NBVA 4A6FA 3UZTA 4TYZA 3BINA 2M14A 4F7GA 4HB3B 3ODXA 1V61A 2LULA 4OT1A 4H8SA 2X18A 4YL8A 1FHXA 2EJ8A 2D9WA 2AEHA 3WYFB 3F5RA 1ZVRA 2DYNA 3SYXA 3ULBA 1PLSA 1E5WA 4HHVA 2E2XA 2D4QA 2RNRB 4HATB 2N23A 2GUMA 4NSWA 2YSZA 1MIXA 3F0WA 1FOEA 4GNKB 4GZUA 2R2YA 2DYQA 2CODA 3LJUX 4GMVA 4A6HA 1ZSQA 2L1CA 2QKLA 1FB8A 2KUQA 1H10A 3M1IB 1UPQA 1V88A 2P0FA 3D8DA 2GCLA 3NWFA 2D11A 3NSUA 2Z59A 1T77A 2RSGA 3PVLA 1EF1A 2EMTA 2I1KA 4EKUA 1X86A 2YT0A 1WG7A 4DXAB 1FGZA 2KIGA 1BWNA 1DDVA 2MFQA 2GCJA 3HQCA 1MAIA 3O96A 2Y7BA 3DXEA 2HE7A 4MT7A 2XQNM 1EVHA 3D8FA 2D2QA 4K2OA 2YRYA 1ZYIA 2DHIA 4B6HA 1V5MA 3VIAA 3B77A 1UNPA 2D9YA 3A8PA 4K81A 3TFMA 1XCGA 2K2JA 2MKRA 5JHGA 5C79A 3AU4A 3PSCA 5HE0A 2P0DA 2ROZB 4KAXB 3TO1A 3PEGA 1LB1A 3P7ZA 3PP2A 1BTNA 4D0NB 1WGQA 1QC6A 5HE1A 4QJ4B 2IYBA 3DXDA 1U5EA 1W1GA 3HW2B 4QXAB 5DI9B 2YS5A 2YF0A 2R0DA 1FHWA 4KHBA 2K8EA 5D3VA 3CXBB 4QJ3B 1N3HA 1X1GA 1XX0A 2LYDA 4GMXB 4K2PA 2ZPYA 3QBVB 2OQBA 2COFA 4GOUA 3HK0A 2Z14A 4BBKA 5JLJB 2COAA 3KZ1A 3U8ZA 2KCJA 2NMBA 4C0AA 2FJUB 5KCVA 2ADZA 5D3YA 4Z2MB 1V5PA 3ZVRA 5C5BA 2GJYA 1AWEA 1UNQA 2ZKMX 5DHAB 4ZRJA 2FJLA 2L2IA 1BAKA 4HAXB 4KHAA 5HE2A 2RGNB 1GG3A 3HIEA 2J0JA 4HSIA 3ZDTA 5D3XA 3PVUA 2DHJA 5EFXA 5L81A 1FAOA 1WVHA 5KQ1A 5M4YB 2CRFA 2Q13A 1J19A 4ZRIA 3SNHA 2W2XC 4TKNA 1DYNA 4HAZB 1V89A 2GS0A 3GYPA 1B55A 5JHHA 1P6SA 2DKPA 2EC1A 4F7HA 4PNKA 1M7RA 3A8QA 3QIJA 2KR0A 2ELAA 4DX90 5D27A 2K00A 4IFSA 4A6FB 2MWNB 3NWDA 2DX5A 3ML4A 2PZ1A 2IFSA 4GPTB 4YONA 5D3WA 3U12A 1ZC4B 2Y8FA 4CHMA 2HTHB 1LW3A 3SV1A 4Y94A 3HSAA 5IRSA 4ZRKA 3KSYA 5FI1A 5JP4A 1MIZB 2Z0OA 4GXBA 1AQCA 1WI1A 1U5DA 3BJIA 5KQ4A 2AL6A 1NTYA 5I2MA 2DN6A 3QWMA 3NWAA 2UZSA 1XODA 2Z0PA 5C16A 1FGYA 1RJ2A 3A58A 2J0MA 2H7EA 1XKEA 1DDMA 3RCPA 2D9ZA 3IVFA 1U29A 5LG4B 3FVCA 2DHKA 1MI1A 4WJ7A 1P3RA 2YT2A 1W1DA 2I1JA 4A5KA 1U5GA 3OHMB 4K17A 1I2HA 4HDOA 4QJ5B 1K5GB 1EGXA 4CYEA 4A6KA 2P0HA 2CY5A 4HAUB 2QKMA 2Y8GA 3A98B 1XR0B 1NTVA 2MDXA 5FI0A 1Q67A 1DDWA 3DXCA 2LOZA 4MK0A 2D9VA 2Z0QA 1J0WA 3D8EA 4KHOA 1PMSA 3PZDA 5I2SA 4DX8A 3PVWA 1GC7A 4XWXA 1OY2A 1FHOA 2ROVA 1MKEA 1SGHA 3PG7A 2UVMA 5GOWB 3U7DA 2DX1A 3V5WA 4WVFB 1UNRA 1U5FA 2J59M 2COCA 4KHBB 1WJ1A 2YT1A 2OTXA 2RVBB 4HAVB 3ULCA 3FM8C 2ELBA 3GYOA 5J3YA 3OANA 1GC6A 4HDQA 3MDBC 1U27A 1TJ6A 4Z2NA 3KY9A 3TVVA 1P5TA 1WGUA 2VKIA 3WA0A 2I5CA 5C5BB 2DFKA 4CHJA 5LOPB 3SO6A 1Y5OA 1X1FA 1SHCA 3TCAA 4WSFA 1W1HA 1V5UA 2LKOA 4HB4B 3AJ4A 1X11A 3X23A 3G9WA 4NY0A 3KRWA 1IRSA 1I7AA 1DBHA 3VOQA 1K5DB 1RRPB 1NI2A 2JP2A 1M7EA 2V76A 3NW8A 5LONB 2D10A 2CY4A 2KUPA 2UZRA 5CLQB 2RUKB 2DKQA 2K49A 4DBBA 3SUZA 2CAYA 2RRFA 1BTKA 1UPRA 4KVGB 1OQNA 3ODOA 2D9XA 1KZGA 2W2XD 4EMOA 4PQ0A 4P7IA 4D6WA 1DROA 5DH9B 2R09A 4CSQA 5J3QA 3KRXA 2K2UA 1X05A 2NZ8B 1ZC3B 2BCJA 1TXDA 3TW1A 3FEHA 1H4RA 3P6AA 2N0YA 3DCXA 1KI1B 1U2BA 4F7UP 1XD4A 2YS3A 3N7CA 1OMWA 3MPXA 3FSSA 2G35A 2W2WA 1PFJA 4HB0B 4GN1A 4OSNA 1MPHA 2EMSA 4IOYX 1KZ7A 2M38A 5J3TA 4EJNA 1MK9B 2VRWB 2DA0A 4DIXA 2J0KA 2LOXA 4HAWB 2Z13A 2DLWA 5DHFB 1MK7B 5DIFB 1Z87A 4IAPA 2KGXB 2YS1A 2P8VA 1EAZA 2LG1A 5CLLB 2H7DA 1QQGA 1WJMA 1UEFA 2YVCA 1Y19B 3ODWA 4L1RA 5C6RA 1TQZA 5HE3A 2VSZA 1NU2A 3CIKA 2I5FA 2DTCA 1ZM0A 3T06A 3AU5A 1ISNA 2RLOA 4L6EA 4HAYB 2KIEA
chains in the Genus database with same CATH topology
4HB2B 4MY6A 4A6FA 3UZTA 4TYZA 3BINA 2M14A 4F7GA 4HB3B 3ODXA 1V61A 2LULA 4H8SA 2X18A 4YL8A 1FHXA 2EJ8A 2D9WA 2AEHA 3WYFB 3F5RA 1ZVRA 2DYNA 3SYXA 3ULBA 1PLSA 1E5WA 4HHVA 2E2XA 2D4QA 2RNRB 4HATB 2N23A 4NSWA 2YSZA 1MIXA 3F0WA 1FOEA 4GZUA 2DYQA 2CODA 3LJUX 4GMVA 4A6HA 1ZSQA 2L1CA 2QKLA 1FB8A 1H10A 3M1IB 1UPQA 1V88A 2P0FA 3D8DA 2GCLA 2D11A 3NSUA 2RSGA 3PVLA 1EF1A 2EMTA 2I1KA 4EKUA 1X86A 2YT0A 1WG7A 4DXAB 1FGZA 1BWNA 1DDVA 2MFQA 2GCJA 3HQCA 1MAIA 3O96A 2Y7BA 3DXEA 2HE7A 4MT7A 2XQNM 1EVHA 3D8FA 2D2QA 4K2OA 2YRYA 2DHIA 4B6HA 1V5MA 3VIAA 1UNPA 2D9YA 3A8PA 4K81A 3TFMA 1XCGA 2K2JA 2MKRA 5JHGA 5C79A 3AU4A 3PSCA 5HE0A 2P0DA 2ROZB 4KAXB 3TO1A 3PEGA 1LB1A 3P7ZA 3PP2A 1BTNA 4D0NB 1WGQA 1QC6A 5HE1A 2IYBA 3DXDA 1U5EA 1W1GA 3HW2B 5DI9B 2YS5A 2YF0A 2R0DA 1FHWA 5D3VA 3CXBB 1N3HA 1X1GA 1XX0A 2LYDA 4GMXB 4K2PA 2ZPYA 3QBVB 2OQBA 2COFA 3HK0A 4BBKA 5JLJB 2COAA 3KZ1A 3U8ZA 2KCJA 2NMBA 4C0AA 5KCVA 2ADZA 5D3YA 4Z2MB 1V5PA 3ZVRA 5C5BA 2GJYA 1AWEA 1UNQA 5DHAB 4ZRJA 2FJLA 2L2IA 1BAKA 4HAXB 4KHAA 5HE2A 2RGNB 1GG3A 2J0JA 3ZDTA 5D3XA 3PVUA 2DHJA 5EFXA 5L81A 1FAOA 1WVHA 5KQ1A 2CRFA 2Q13A 1J19A 4ZRIA 3SNHA 2W2XC 4TKNA 1DYNA 4HAZB 1V89A 2GS0A 3GYPA 1B55A 5JHHA 1P6SA 2DKPA 2EC1A 4F7HA 4PNKA 1M7RA 3A8QA 3QIJA 2ELAA 4DX90 5D27A 2K00A 4IFSA 4A6FB 2MWNB 2DX5A 3ML4A 2PZ1A 2IFSA 4GPTB 4YONA 5D3WA 1ZC4B 2Y8FA 4CHMA 2HTHB 1LW3A 3SV1A 4Y94A 4ZRKA 3KSYA 5FI1A 5JP4A 1MIZB 2Z0OA 4GXBA 1AQCA 1WI1A 1U5DA 3BJIA 5KQ4A 2AL6A 1NTYA 2DN6A 3QWMA 2UZSA 1XODA 2Z0PA 5C16A 1FGYA 1RJ2A 2J0MA 2H7EA 1XKEA 1DDMA 3RCPA 2D9ZA 3IVFA 1U29A 2DHKA 4WJ7A 1P3RA 1W1DA 2I1JA 4A5KA 1U5GA 4K17A 1I2HA 4HDOA 1K5GB 1EGXA 4CYEA 4A6KA 2P0HA 2CY5A 4HAUB 2QKMA 2Y8GA 3A98B 1XR0B 1NTVA 2MDXA 5FI0A 1Q67A 1DDWA 3DXCA 2LOZA 4MK0A 2D9VA 2Z0QA 1J0WA 3D8EA 4KHOA 1PMSA 3PZDA 4DX8A 3PVWA 1GC7A 4XWXA 1OY2A 1FHOA 2ROVA 1MKEA 1SGHA 3PG7A 2UVMA 5GOWB 3U7DA 2DX1A 3V5WA 4WVFB 1UNRA 1U5FA 2J59M 2COCA 4KHBB 1WJ1A 2YT1A 2OTXA 2RVBB 4HAVB 3ULCA 3FM8C 2ELBA 3GYOA 5J3YA 3OANA 1GC6A 4HDQA 3MDBC 1U27A 1TJ6A 4Z2NA 3KY9A 3TVVA 1P5TA 1WGUA 2VKIA 3WA0A 2I5CA 5C5BB 2DFKA 4CHJA 5LOPB 3SO6A 1Y5OA 1X1FA 1SHCA 3TCAA 4WSFA 1W1HA 1V5UA 2LKOA 4HB4B 3AJ4A 1X11A 3X23A 3G9WA 4NY0A 3KRWA 1IRSA 1I7AA 1DBHA 3VOQA 1K5DB 1RRPB 1NI2A 2JP2A 1M7EA 2V76A 5LONB 2D10A 2CY4A 2KUPA 2UZRA 5CLQB 2RUKB 2DKQA 4DBBA 3SUZA 2CAYA 1BTKA 1UPRA 4KVGB 1OQNA 3ODOA 2D9XA 1KZGA 2W2XD 4EMOA 4PQ0A 4P7IA 1DROA 5DH9B 2R09A 5J3QA 3KRXA 2K2UA 1X05A 2NZ8B 1ZC3B 2BCJA 1TXDA 3TW1A 3FEHA 1H4RA 3P6AA 2N0YA 1KI1B 1U2BA 4F7UP 1XD4A 2YS3A 3N7CA 1OMWA 3MPXA 3FSSA 2G35A 2W2WA 1PFJA 4HB0B 4GN1A 1MPHA 2EMSA 4IOYX 1KZ7A 2M38A 5J3TA 4EJNA 1MK9B 2VRWB 2DA0A 2J0KA 2LOXA 4HAWB 2DLWA 5DHFB 1MK7B 5DIFB 1Z87A 4IAPA 2KGXB 2YS1A 2P8VA 1EAZA 2LG1A 5CLLB 2H7DA 1QQGA 1WJMA 1UEFA 2YVCA 1Y19B 3ODWA 5C6RA 1TQZA 5HE3A 2VSZA 1NU2A 3CIKA 2I5FA 2DTCA 1ZM0A 3T06A 3AU5A 1ISNA 2RLOA 4L6EA 4HAYB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HB2 B;  4MY6 A;  4A6F A;  3UZT A;  4TYZ A;  3BIN A;  2M14 A;  4F7G A;  4HB3 B;  3ODX A;  1V61 A;  2LUL A;  4H8S A;  2X18 A;  4YL8 A;  1FHX A;  2EJ8 A;  2D9W A;  2AEH A;  3WYF B;  3F5R A;  1ZVR A;  2DYN A;  3SYX A;  3ULB A;  1PLS A;  1E5W A;  4HHV A;  2E2X A;  2D4Q A;  2RNR B;  4HAT B;  2N23 A;  4NSW A;  2YSZ A;  1MIX A;  3F0W A;  1FOE A;  4GZU A;  2DYQ A;  2COD A;  3LJU X;  4GMV A;  4A6H A;  1ZSQ A;  2L1C A;  2QKL A;  1FB8 A;  1H10 A;  3M1I B;  1UPQ A;  1V88 A;  2P0F A;  3D8D A;  2GCL A;  2D11 A;  3NSU A;  2RSG A;  3PVL A;  1EF1 A;  2EMT A;  2I1K A;  4EKU A;  1X86 A;  2YT0 A;  1WG7 A;  4DXA B;  1FGZ A;  1BWN A;  1DDV A;  2MFQ A;  2GCJ A;  3HQC A;  1MAI A;  3O96 A;  2Y7B A;  3DXE A;  2HE7 A;  4MT7 A;  2XQN M;  1EVH A;  3D8F A;  2D2Q A;  4K2O A;  2YRY A;  2DHI A;  4B6H A;  1V5M A;  3VIA A;  1UNP A;  2D9Y A;  3A8P A;  4K81 A;  3TFM A;  1XCG A;  2K2J A;  2MKR A;  5JHG A;  5C79 A;  3AU4 A;  3PSC A;  5HE0 A;  2P0D A;  2ROZ B;  4KAX B;  3TO1 A;  3PEG A;  1LB1 A;  3P7Z A;  3PP2 A;  1BTN A;  4D0N B;  1WGQ A;  1QC6 A;  5HE1 A;  2IYB A;  3DXD A;  1U5E A;  1W1G A;  3HW2 B;  5DI9 B;  2YS5 A;  2YF0 A;  2R0D A;  1FHW A;  5D3V A;  3CXB B;  1N3H A;  1X1G A;  1XX0 A;  2LYD A;  4GMX B;  4K2P A;  2ZPY A;  3QBV B;  2OQB A;  2COF A;  3HK0 A;  4BBK A;  5JLJ B;  2COA A;  3KZ1 A;  3U8Z A;  2KCJ A;  2NMB A;  4C0A A;  5KCV A;  2ADZ A;  5D3Y A;  4Z2M B;  1V5P A;  3ZVR A;  5C5B A;  2GJY A;  1AWE A;  1UNQ A;  5DHA B;  4ZRJ A;  2FJL A;  2L2I A;  1BAK A;  4HAX B;  4KHA A;  5HE2 A;  2RGN B;  1GG3 A;  2J0J A;  3ZDT A;  5D3X A;  3PVU A;  2DHJ A;  5EFX A;  5L81 A;  1FAO A;  1WVH A;  5KQ1 A;  2CRF A;  2Q13 A;  1J19 A;  4ZRI A;  3SNH A;  2W2X C;  4TKN A;  1DYN A;  4HAZ B;  1V89 A;  2GS0 A;  3GYP A;  1B55 A;  5JHH A;  1P6S A;  2DKP A;  2EC1 A;  4F7H A;  4PNK A;  1M7R A;  3A8Q A;  3QIJ A;  2ELA A;  4DX9 0;  5D27 A;  2K00 A;  4IFS A;  4A6F B;  2MWN B;  2DX5 A;  3ML4 A;  2PZ1 A;  2IFS A;  4GPT B;  4YON A;  5D3W A;  1ZC4 B;  2Y8F A;  4CHM A;  2HTH B;  1LW3 A;  3SV1 A;  4Y94 A;  4ZRK A;  3KSY A;  5FI1 A;  5JP4 A;  1MIZ B;  2Z0O A;  4GXB A;  1AQC A;  1WI1 A;  1U5D A;  3BJI A;  5KQ4 A;  2AL6 A;  1NTY A;  2DN6 A;  3QWM A;  2UZS A;  1XOD A;  2Z0P A;  5C16 A;  1FGY A;  1RJ2 A;  2J0M A;  2H7E A;  1XKE A;  1DDM A;  3RCP A;  2D9Z A;  3IVF A;  1U29 A;  2DHK A;  4WJ7 A;  1P3R A;  1W1D A;  2I1J A;  4A5K A;  1U5G A;  4K17 A;  1I2H A;  4HDO A;  1K5G B;  1EGX A;  4CYE A;  4A6K A;  2P0H A;  2CY5 A;  4HAU B;  2QKM A;  2Y8G A;  3A98 B;  1XR0 B;  1NTV A;  2MDX A;  5FI0 A;  1Q67 A;  1DDW A;  3DXC A;  2LOZ A;  4MK0 A;  2D9V A;  2Z0Q A;  1J0W A;  3D8E A;  4KHO A;  1PMS A;  3PZD A;  4DX8 A;  3PVW A;  1GC7 A;  4XWX A;  1OY2 A;  1FHO A;  2ROV A;  1MKE A;  1SGH A;  3PG7 A;  2UVM A;  5GOW B;  3U7D A;  2DX1 A;  3V5W A;  4WVF B;  1UNR A;  1U5F A;  2J59 M;  2COC A;  4KHB B;  1WJ1 A;  2YT1 A;  2OTX A;  2RVB B;  4HAV B;  3ULC A;  3FM8 C;  2ELB A;  3GYO A;  5J3Y A;  3OAN A;  1GC6 A;  4HDQ A;  3MDB C;  1U27 A;  1TJ6 A;  4Z2N A;  3KY9 A;  3TVV A;  1P5T A;  1WGU A;  2VKI A;  3WA0 A;  2I5C A;  5C5B B;  2DFK A;  4CHJ A;  5LOP B;  3SO6 A;  1Y5O A;  1X1F A;  1SHC A;  3TCA A;  4WSF A;  1W1H A;  1V5U A;  2LKO A;  4HB4 B;  3AJ4 A;  1X11 A;  3X23 A;  3G9W A;  4NY0 A;  3KRW A;  1IRS A;  1I7A A;  1DBH A;  3VOQ A;  1K5D B;  1RRP B;  1NI2 A;  2JP2 A;  1M7E A;  2V76 A;  5LON B;  2D10 A;  2CY4 A;  2KUP A;  2UZR A;  5CLQ B;  2RUK B;  2DKQ A;  4DBB A;  3SUZ A;  2CAY A;  1BTK A;  1UPR A;  4KVG B;  1OQN A;  3ODO A;  2D9X A;  1KZG A;  2W2X D;  4EMO A;  4PQ0 A;  4P7I A;  1DRO A;  5DH9 B;  2R09 A;  5J3Q A;  3KRX A;  2K2U A;  1X05 A;  2NZ8 B;  1ZC3 B;  2BCJ A;  1TXD A;  3TW1 A;  3FEH A;  1H4R A;  3P6A A;  2N0Y A;  1KI1 B;  1U2B A;  4F7U P;  1XD4 A;  2YS3 A;  3N7C A;  1OMW A;  3MPX A;  3FSS A;  2G35 A;  2W2W A;  1PFJ A;  4HB0 B;  4GN1 A;  1MPH A;  2EMS A;  4IOY X;  1KZ7 A;  2M38 A;  5J3T A;  4EJN A;  1MK9 B;  2VRW B;  2DA0 A;  2J0K A;  2LOX A;  4HAW B;  2DLW A;  5DHF B;  1MK7 B;  5DIF B;  1Z87 A;  4IAP A;  2KGX B;  2YS1 A;  2P8V A;  1EAZ A;  2LG1 A;  5CLL B;  2H7D A;  1QQG A;  1WJM A;  1UEF A;  2YVC A;  1Y19 B;  3ODW A;  5C6R A;  1TQZ A;  5HE3 A;  2VSZ A;  1NU2 A;  3CIK A;  2I5F A;  2DTC A;  1ZM0 A;  3T06 A;  3AU5 A;  1ISN A;  2RLO A;  4L6E A;  4HAY B; 
#chains in the Genus database with same CATH topology
 2Z4D A;  4HB2 B;  4MY6 A;  2NBV A;  4A6F A;  3UZT A;  4TYZ A;  3BIN A;  2M14 A;  4F7G A;  4HB3 B;  3ODX A;  1V61 A;  2LUL A;  4OT1 A;  4H8S A;  2X18 A;  4YL8 A;  1FHX A;  2EJ8 A;  2D9W A;  2AEH A;  3WYF B;  3F5R A;  1ZVR A;  2DYN A;  3SYX A;  3ULB A;  1PLS A;  1E5W A;  4HHV A;  2E2X A;  2D4Q A;  2RNR B;  4HAT B;  2N23 A;  2GUM A;  4NSW A;  2YSZ A;  1MIX A;  3F0W A;  1FOE A;  4GNK B;  4GZU A;  2R2Y A;  2DYQ A;  2COD A;  3LJU X;  4GMV A;  4A6H A;  1ZSQ A;  2L1C A;  2QKL A;  1FB8 A;  2KUQ A;  1H10 A;  3M1I B;  1UPQ A;  1V88 A;  2P0F A;  3D8D A;  2GCL A;  3NWF A;  2D11 A;  3NSU A;  2Z59 A;  1T77 A;  2RSG A;  3PVL A;  1EF1 A;  2EMT A;  2I1K A;  4EKU A;  1X86 A;  2YT0 A;  1WG7 A;  4DXA B;  1FGZ A;  2KIG A;  1BWN A;  1DDV A;  2MFQ A;  2GCJ A;  3HQC A;  1MAI A;  3O96 A;  2Y7B A;  3DXE A;  2HE7 A;  4MT7 A;  2XQN M;  1EVH A;  3D8F A;  2D2Q A;  4K2O A;  2YRY A;  1ZYI A;  2DHI A;  4B6H A;  1V5M A;  3VIA A;  3B77 A;  1UNP A;  2D9Y A;  3A8P A;  4K81 A;  3TFM A;  1XCG A;  2K2J A;  2MKR A;  5JHG A;  5C79 A;  3AU4 A;  3PSC A;  5HE0 A;  2P0D A;  2ROZ B;  4KAX B;  3TO1 A;  3PEG A;  1LB1 A;  3P7Z A;  3PP2 A;  1BTN A;  4D0N B;  1WGQ A;  1QC6 A;  5HE1 A;  4QJ4 B;  2IYB A;  3DXD A;  1U5E A;  1W1G A;  3HW2 B;  4QXA B;  5DI9 B;  2YS5 A;  2YF0 A;  2R0D A;  1FHW A;  4KHB A;  2K8E A;  5D3V A;  3CXB B;  4QJ3 B;  1N3H A;  1X1G A;  1XX0 A;  2LYD A;  4GMX B;  4K2P A;  2ZPY A;  3QBV B;  2OQB A;  2COF A;  4GOU A;  3HK0 A;  2Z14 A;  4BBK A;  5JLJ B;  2COA A;  3KZ1 A;  3U8Z A;  2KCJ A;  2NMB A;  4C0A A;  2FJU B;  5KCV A;  2ADZ A;  5D3Y A;  4Z2M B;  1V5P A;  3ZVR A;  5C5B A;  2GJY A;  1AWE A;  1UNQ A;  2ZKM X;  5DHA B;  4ZRJ A;  2FJL A;  2L2I A;  1BAK A;  4HAX B;  4KHA A;  5HE2 A;  2RGN B;  1GG3 A;  3HIE A;  2J0J A;  4HSI A;  3ZDT A;  5D3X A;  3PVU A;  2DHJ A;  5EFX A;  5L81 A;  1FAO A;  1WVH A;  5KQ1 A;  5M4Y B;  2CRF A;  2Q13 A;  1J19 A;  4ZRI A;  3SNH A;  2W2X C;  4TKN A;  1DYN A;  4HAZ B;  1V89 A;  2GS0 A;  3GYP A;  1B55 A;  5JHH A;  1P6S A;  2DKP A;  2EC1 A;  4F7H A;  4PNK A;  1M7R A;  3A8Q A;  3QIJ A;  2KR0 A;  2ELA A;  4DX9 0;  5D27 A;  2K00 A;  4IFS A;  4A6F B;  2MWN B;  3NWD A;  2DX5 A;  3ML4 A;  2PZ1 A;  2IFS A;  4GPT B;  4YON A;  5D3W A;  3U12 A;  1ZC4 B;  2Y8F A;  4CHM A;  2HTH B;  1LW3 A;  3SV1 A;  4Y94 A;  3HSA A;  5IRS A;  4ZRK A;  3KSY A;  5FI1 A;  5JP4 A;  1MIZ B;  2Z0O A;  4GXB A;  1AQC A;  1WI1 A;  1U5D A;  3BJI A;  5KQ4 A;  2AL6 A;  1NTY A;  5I2M A;  2DN6 A;  3QWM A;  3NWA A;  2UZS A;  1XOD A;  2Z0P A;  5C16 A;  1FGY A;  1RJ2 A;  3A58 A;  2J0M A;  2H7E A;  1XKE A;  1DDM A;  3RCP A;  2D9Z A;  3IVF A;  1U29 A;  5LG4 B;  3FVC A;  2DHK A;  1MI1 A;  4WJ7 A;  1P3R A;  2YT2 A;  1W1D A;  2I1J A;  4A5K A;  1U5G A;  3OHM B;  4K17 A;  1I2H A;  4HDO A;  4QJ5 B;  1K5G B;  1EGX A;  4CYE A;  4A6K A;  2P0H A;  2CY5 A;  4HAU B;  2QKM A;  2Y8G A;  3A98 B;  1XR0 B;  1NTV A;  2MDX A;  5FI0 A;  1Q67 A;  1DDW A;  3DXC A;  2LOZ A;  4MK0 A;  2D9V A;  2Z0Q A;  1J0W A;  3D8E A;  4KHO A;  1PMS A;  3PZD A;  5I2S A;  4DX8 A;  3PVW A;  1GC7 A;  4XWX A;  1OY2 A;  1FHO A;  2ROV A;  1MKE A;  1SGH A;  3PG7 A;  2UVM A;  5GOW B;  3U7D A;  2DX1 A;  3V5W A;  4WVF B;  1UNR A;  1U5F A;  2J59 M;  2COC A;  4KHB B;  1WJ1 A;  2YT1 A;  2OTX A;  2RVB B;  4HAV B;  3ULC A;  3FM8 C;  2ELB A;  3GYO A;  5J3Y A;  3OAN A;  1GC6 A;  4HDQ A;  3MDB C;  1U27 A;  1TJ6 A;  4Z2N A;  3KY9 A;  3TVV A;  1P5T A;  1WGU A;  2VKI A;  3WA0 A;  2I5C A;  5C5B B;  2DFK A;  4CHJ A;  5LOP B;  3SO6 A;  1Y5O A;  1X1F A;  1SHC A;  3TCA A;  4WSF A;  1W1H A;  1V5U A;  2LKO A;  4HB4 B;  3AJ4 A;  1X11 A;  3X23 A;  3G9W A;  4NY0 A;  3KRW A;  1IRS A;  1I7A A;  1DBH A;  3VOQ A;  1K5D B;  1RRP B;  1NI2 A;  2JP2 A;  1M7E A;  2V76 A;  3NW8 A;  5LON B;  2D10 A;  2CY4 A;  2KUP A;  2UZR A;  5CLQ B;  2RUK B;  2DKQ A;  2K49 A;  4DBB A;  3SUZ A;  2CAY A;  2RRF A;  1BTK A;  1UPR A;  4KVG B;  1OQN A;  3ODO A;  2D9X A;  1KZG A;  2W2X D;  4EMO A;  4PQ0 A;  4P7I A;  4D6W A;  1DRO A;  5DH9 B;  2R09 A;  4CSQ A;  5J3Q A;  3KRX A;  2K2U A;  1X05 A;  2NZ8 B;  1ZC3 B;  2BCJ A;  1TXD A;  3TW1 A;  3FEH A;  1H4R A;  3P6A A;  2N0Y A;  3DCX A;  1KI1 B;  1U2B A;  4F7U P;  1XD4 A;  2YS3 A;  3N7C A;  1OMW A;  3MPX A;  3FSS A;  2G35 A;  2W2W A;  1PFJ A;  4HB0 B;  4GN1 A;  4OSN A;  1MPH A;  2EMS A;  4IOY X;  1KZ7 A;  2M38 A;  5J3T A;  4EJN A;  1MK9 B;  2VRW B;  2DA0 A;  4DIX A;  2J0K A;  2LOX A;  4HAW B;  2Z13 A;  2DLW A;  5DHF B;  1MK7 B;  5DIF B;  1Z87 A;  4IAP A;  2KGX B;  2YS1 A;  2P8V A;  1EAZ A;  2LG1 A;  5CLL B;  2H7D A;  1QQG A;  1WJM A;  1UEF A;  2YVC A;  1Y19 B;  3ODW A;  4L1R A;  5C6R A;  1TQZ A;  5HE3 A;  2VSZ A;  1NU2 A;  3CIK A;  2I5F A;  2DTC A;  1ZM0 A;  3T06 A;  3AU5 A;  1ISN A;  2RLO A;  4L6E A;  4HAY B;  2KIE A; 
#chains in the Genus database with same CATH homology
 4HB2 B;  4MY6 A;  4A6F A;  3UZT A;  4TYZ A;  3BIN A;  2M14 A;  4F7G A;  4HB3 B;  3ODX A;  1V61 A;  2LUL A;  4H8S A;  2X18 A;  4YL8 A;  1FHX A;  2EJ8 A;  2D9W A;  2AEH A;  3WYF B;  3F5R A;  1ZVR A;  2DYN A;  3SYX A;  3ULB A;  1PLS A;  1E5W A;  4HHV A;  2E2X A;  2D4Q A;  2RNR B;  4HAT B;  2N23 A;  4NSW A;  2YSZ A;  1MIX A;  3F0W A;  1FOE A;  4GZU A;  2DYQ A;  2COD A;  3LJU X;  4GMV A;  4A6H A;  1ZSQ A;  2L1C A;  2QKL A;  1FB8 A;  1H10 A;  3M1I B;  1UPQ A;  1V88 A;  2P0F A;  3D8D A;  2GCL A;  2D11 A;  3NSU A;  2RSG A;  3PVL A;  1EF1 A;  2EMT A;  2I1K A;  4EKU A;  1X86 A;  2YT0 A;  1WG7 A;  4DXA B;  1FGZ A;  1BWN A;  1DDV A;  2MFQ A;  2GCJ A;  3HQC A;  1MAI A;  3O96 A;  2Y7B A;  3DXE A;  2HE7 A;  4MT7 A;  2XQN M;  1EVH A;  3D8F A;  2D2Q A;  4K2O A;  2YRY A;  2DHI A;  4B6H A;  1V5M A;  3VIA A;  1UNP A;  2D9Y A;  3A8P A;  4K81 A;  3TFM A;  1XCG A;  2K2J A;  2MKR A;  5JHG A;  5C79 A;  3AU4 A;  3PSC A;  5HE0 A;  2P0D A;  2ROZ B;  4KAX B;  3TO1 A;  3PEG A;  1LB1 A;  3P7Z A;  3PP2 A;  1BTN A;  4D0N B;  1WGQ A;  1QC6 A;  5HE1 A;  2IYB A;  3DXD A;  1U5E A;  1W1G A;  3HW2 B;  5DI9 B;  2YS5 A;  2YF0 A;  2R0D A;  1FHW A;  5D3V A;  3CXB B;  1N3H A;  1X1G A;  1XX0 A;  2LYD A;  4GMX B;  4K2P A;  2ZPY A;  3QBV B;  2OQB A;  2COF A;  3HK0 A;  4BBK A;  5JLJ B;  2COA A;  3KZ1 A;  3U8Z A;  2KCJ A;  2NMB A;  4C0A A;  5KCV A;  2ADZ A;  5D3Y A;  4Z2M B;  1V5P A;  3ZVR A;  5C5B A;  2GJY A;  1AWE A;  1UNQ A;  5DHA B;  4ZRJ A;  2FJL A;  2L2I A;  1BAK A;  4HAX B;  4KHA A;  5HE2 A;  2RGN B;  1GG3 A;  2J0J A;  3ZDT A;  5D3X A;  3PVU A;  2DHJ A;  5EFX A;  5L81 A;  1FAO A;  1WVH A;  5KQ1 A;  2CRF A;  2Q13 A;  1J19 A;  4ZRI A;  3SNH A;  2W2X C;  4TKN A;  1DYN A;  4HAZ B;  1V89 A;  2GS0 A;  3GYP A;  1B55 A;  5JHH A;  1P6S A;  2DKP A;  2EC1 A;  4F7H A;  4PNK A;  1M7R A;  3A8Q A;  3QIJ A;  2ELA A;  4DX9 0;  5D27 A;  2K00 A;  4IFS A;  4A6F B;  2MWN B;  2DX5 A;  3ML4 A;  2PZ1 A;  2IFS A;  4GPT B;  4YON A;  5D3W A;  1ZC4 B;  2Y8F A;  4CHM A;  2HTH B;  1LW3 A;  3SV1 A;  4Y94 A;  4ZRK A;  3KSY A;  5FI1 A;  5JP4 A;  1MIZ B;  2Z0O A;  4GXB A;  1AQC A;  1WI1 A;  1U5D A;  3BJI A;  5KQ4 A;  2AL6 A;  1NTY A;  2DN6 A;  3QWM A;  2UZS A;  1XOD A;  2Z0P A;  5C16 A;  1FGY A;  1RJ2 A;  2J0M A;  2H7E A;  1XKE A;  1DDM A;  3RCP A;  2D9Z A;  3IVF A;  1U29 A;  2DHK A;  4WJ7 A;  1P3R A;  1W1D A;  2I1J A;  4A5K A;  1U5G A;  4K17 A;  1I2H A;  4HDO A;  1K5G B;  1EGX A;  4CYE A;  4A6K A;  2P0H A;  2CY5 A;  4HAU B;  2QKM A;  2Y8G A;  3A98 B;  1XR0 B;  1NTV A;  2MDX A;  5FI0 A;  1Q67 A;  1DDW A;  3DXC A;  2LOZ A;  4MK0 A;  2D9V A;  2Z0Q A;  1J0W A;  3D8E A;  4KHO A;  1PMS A;  3PZD A;  4DX8 A;  3PVW A;  1GC7 A;  4XWX A;  1OY2 A;  1FHO A;  2ROV A;  1MKE A;  1SGH A;  3PG7 A;  2UVM A;  5GOW B;  3U7D A;  2DX1 A;  3V5W A;  4WVF B;  1UNR A;  1U5F A;  2J59 M;  2COC A;  4KHB B;  1WJ1 A;  2YT1 A;  2OTX A;  2RVB B;  4HAV B;  3ULC A;  3FM8 C;  2ELB A;  3GYO A;  5J3Y A;  3OAN A;  1GC6 A;  4HDQ A;  3MDB C;  1U27 A;  1TJ6 A;  4Z2N A;  3KY9 A;  3TVV A;  1P5T A;  1WGU A;  2VKI A;  3WA0 A;  2I5C A;  5C5B B;  2DFK A;  4CHJ A;  5LOP B;  3SO6 A;  1Y5O A;  1X1F A;  1SHC A;  3TCA A;  4WSF A;  1W1H A;  1V5U A;  2LKO A;  4HB4 B;  3AJ4 A;  1X11 A;  3X23 A;  3G9W A;  4NY0 A;  3KRW A;  1IRS A;  1I7A A;  1DBH A;  3VOQ A;  1K5D B;  1RRP B;  1NI2 A;  2JP2 A;  1M7E A;  2V76 A;  5LON B;  2D10 A;  2CY4 A;  2KUP A;  2UZR A;  5CLQ B;  2RUK B;  2DKQ A;  4DBB A;  3SUZ A;  2CAY A;  1BTK A;  1UPR A;  4KVG B;  1OQN A;  3ODO A;  2D9X A;  1KZG A;  2W2X D;  4EMO A;  4PQ0 A;  4P7I A;  1DRO A;  5DH9 B;  2R09 A;  5J3Q A;  3KRX A;  2K2U A;  1X05 A;  2NZ8 B;  1ZC3 B;  2BCJ A;  1TXD A;  3TW1 A;  3FEH A;  1H4R A;  3P6A A;  2N0Y A;  1KI1 B;  1U2B A;  4F7U P;  1XD4 A;  2YS3 A;  3N7C A;  1OMW A;  3MPX A;  3FSS A;  2G35 A;  2W2W A;  1PFJ A;  4HB0 B;  4GN1 A;  1MPH A;  2EMS A;  4IOY X;  1KZ7 A;  2M38 A;  5J3T A;  4EJN A;  1MK9 B;  2VRW B;  2DA0 A;  2J0K A;  2LOX A;  4HAW B;  2DLW A;  5DHF B;  1MK7 B;  5DIF B;  1Z87 A;  4IAP A;  2KGX B;  2YS1 A;  2P8V A;  1EAZ A;  2LG1 A;  5CLL B;  2H7D A;  1QQG A;  1WJM A;  1UEF A;  2YVC A;  1Y19 B;  3ODW A;  5C6R A;  1TQZ A;  5HE3 A;  2VSZ A;  1NU2 A;  3CIK A;  2I5F A;  2DTC A;  1ZM0 A;  3T06 A;  3AU5 A;  1ISN A;  2RLO A;  4L6E A;  4HAY B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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