4K2OA

The structure of a triple mutant of the tiam1 ph-cc-ex domain
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
240
structure length
232
Chain Sequence
b'GTVRKAGALAVKNFLVHKKNKKVESATRRKWKHYWVSLKGCTLFFYESDGIPKHAVWVENSIVQAVPEHPKKDFVFCLSNSLGDAFLFQTTSQTELENWITAIHSACATAVARHHHKEDTLRLLKSEIKKLEQKIDMDEKMKKMGEMQLSSVTDSKAAATILDQIFVWEQNLEQFQMDLFRFRCYLASLQGGELPNPKRLLAFASRPTKVAMGRLGIFSVSSFHALVAARTG'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords T-lymphoma invasion and metastasis-inducing protein 1
publication title High-resolution structure of the Tiam1 PHn-CC-Ex domain.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Signaling protein
total genus 73
structure length 232
sequence length 240
ec nomenclature
pdb deposition date 2013-04-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF18385 Tiam_CC_Ex T-lymphoma invasion and metastasis CC-Ex domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 4k2oA01
3U7DA 1EVHA 3SO6A 4DBBA 2CRFA 3SYXA 2DYQA 4K2OA 4TYZA 1TJ6A 1KZGA 3F5RA 1U5FA 1U2BA 3KRXA 3HK0A 1LB1A 3FM8C 2KCJA 3GYOA 4A6HA 5D3XA 1XCGA 3DXCA 3F0WA 2D9VA 3QWMA 2CAYA 2BCJA 2VSZA 2DKPA 4IOYX 3A8PA 1MK7B 3A98B 1J0WA 2RNRB 1MKEA 4CYEA 1TQZA 1Z87A 1E5WA 1XX0A 1XR0B 5LONB 5C6RA 1V89A 5JHGA 2FJLA 2AL6A 2RGNB 2UZRA 4MY6A 1WJ1A 5C79A 5KCVA 5J3QA 3ULBA 2I1JA 4IAPA 5DI9B 2JP2A 5D27A 3FEHA 1OY2A 3P7ZA 1DBHA 2GCJA 4K17A 1FGZA 4HAZB 4YONA 5JP4A 2YS5A 1FAOA 2CY5A 4TKNA 3SUZA 1X1FA 3KSYA 2ZPYA 2IFSA 2LYDA 4MT7A 2GCLA 1Q67A 5C5BB 2DKQA 4HB2B 4D0NB 3D8EA 2P0FA 1K5GB 1WVHA 1XODA 4PQ0A 2Z0PA 2M38A 1U5GA 1J19A 3G9WA 1M7EA 2MWNB 1FGYA 3KZ1A 1IRSA 5JHHA 3AU4A 3NSUA 3ZVRA 1Y5OA 1DDMA 1BWNA 2XQNM 2I1KA 2D9WA 4CHMA 2OTXA 1OMWA 2LULA 2W2XD 2LOXA 3PVUA 2YSZA 4P7IA 2Z0QA 1ZC3B 1PMSA 2ROZB 1H10A 1XKEA 4HB0B 2KUPA 1BTNA 3LJUX 3ODXA 1NI2A 2QKMA 4WSFA 3AU5A 1FOEA 3D8DA 2NZ8B 1UNQA 1UNPA 2DX1A 4KAXB 3N7CA 2YRYA 4HB3B 2Y7BA 3KRWA 2EMTA 5DIFB 4EMOA 2J0KA 5C16A 1H4RA 5CLLB 2P0DA 2W2XC 2RUKB 4L6EA 4GMVA 4HB4B 5J3TA 2GS0A 2ADZA 3T06A 1KI1B 3PSCA 1EF1A 1ISNA 5FI1A 4B6HA 4GZUA 5EFXA 2COAA 1UEFA 2J0JA 2DX5A 4ZRJA 2COCA 5JLJB 1DDVA 3HQCA 5GOWB 4Z2MB 1MAIA 3WA0A 1V88A 1FHOA 4HAWB 3P6AA 1MIZB 4MK0A 2YF0A 1X1GA 3FSSA 3X23A 1GC7A 4A6FA 3MDBC 1FHXA 5HE3A 4KHAA 1KZ7A 3V5WA 4WJ7A 1LW3A 1I7AA 1ZSQA 1P6SA 4HAUB 1V61A 2EC1A 2OQBA 2VKIA 2NMBA 2PZ1A 3TO1A 2E2XA 4A5KA 4ZRIA 4A6KA 1ZC4B 3TW1A 4HHVA 3VOQA 3ULCA 5D3VA 2W2WA 2IYBA 3AJ4A 1WJMA 3CXBB 1W1GA 2D4QA 2MFQA 4F7GA 2GJYA 2ELAA 2D2QA 2M14A 3ZDTA 1PLSA 2Q13A 4K2PA 4Y94A 3PZDA 2V76A 1RRPB 1UNRA 2DN6A 3DXDA 1P5TA 1DROA 4GPTB 4YL8A 3PP2A 1AQCA 3D8FA 3VIAA 2DHKA 3QIJA 2DTCA 1SGHA 2VRWB 1SHCA 2COFA 2J0MA 1GG3A 4HDOA 4HDQA 1MK9B 2D9XA 2ROVA 2HTHB 4GMXB 2L2IA 2DHJA 2UZSA 1QC6A 2YVCA 1U5EA 1NTYA 3M1IB 2L1CA 1WG7A 1W1HA 3BINA 2UVMA 1UPQA 2DHIA 2DFKA 3WYFB 1V5PA 2X18A 2K2UA 2R09A 1ZM0A 2P0HA 3O96A 3GYPA 3TCAA 4KHBB 2RVBB 1EAZA 4HAYB 4K81A 1X86A 2D11A 2R0DA 1U27A 1V5MA 2I5FA 5D3WA 1RJ2A 1EGXA 1WGQA 3A8QA 5DH9B 2LKOA 1X11A 3TVVA 3OANA 3RCPA 3TFMA 2K00A 3CIKA 2LOZA 1MIXA 5FI0A 4A6FB 1DYNA 1XD4A 1MPHA 2YT1A 5DHAB 2ELBA 4GN1A 2D9YA 5D3YA 3BJIA 4EJNA 4C0AA 2QKLA 3ODOA 3SNHA 2D9ZA 2DLWA 3MPXA 3KY9A 2CY4A 4HAXB 2HE7A 1B55A 3SV1A 1ZVRA 2MKRA 4PNKA 1X05A 4KHOA 5KQ4A 1FB8A 4CHJA 1NU2A 2G35A 2KGXB 4GXBA 2Y8FA 1AWEA 5KQ1A 2P8VA 3U8ZA 1PFJA 3PVWA 2Y8GA 2DYNA 3PVLA 1BAKA 4DXAB 4KVGB 2AEHA 4Z2NA 2I5CA 2YT0A 3QBVB 2Z0OA 4F7HA 5C5BA 5CLQB 4ZRKA 2H7EA 2EMSA 1FHWA 4EKUA 3UZTA 2N0YA 1P3RA 1OQNA 2DA0A 2EJ8A 1N3HA 3ODWA 2RLOA 1UPRA 2LG1A 4NY0A 1WI1A 1M7RA 4DX90 5HE1A 2YS1A 1DDWA 5J3YA 1U5DA 3IVFA 3PEGA 1K5DB 1W1DA 5LOPB 5HE2A 3PG7A 1TXDA 2YS3A 3HW2B 2MDXA 2N23A 5DHFB 1NTVA 5L81A 2J59M 1Y19B 2H7DA 4WVFB 4F7UP 2CODA 4IFSA 4XWXA 2RSGA 4HATB 4HAVB 5HE0A 2K2JA 1V5UA 4BBKA 4NSWA 1U29A 1GC6A 3ML4A 4H8SA 4DX8A 1QQGA 2D10A 3DXEA 1WGUA 1BTKA 1I2HA
chains in the Genus database with same CATH superfamily
3U7DA 1EVHA 3SO6A 4DBBA 2CRFA 3SYXA 2DYQA 4K2OA 4TYZA 1TJ6A 1KZGA 3F5RA 1U5FA 1U2BA 3FVCA 3KRXA 3HK0A 1LB1A 3FM8C 2KCJA 3GYOA 4A6HA 5D3XA 1XCGA 3DXCA 3F0WA 4QXAB 2D9VA 3QWMA 2CAYA 2BCJA 2VSZA 2DKPA 4IOYX 3A8PA 1MK7B 3A98B 1J0WA 2RNRB 1MKEA 4CYEA 1TQZA 1Z87A 1E5WA 1XX0A 1XR0B 4HSIA 5LONB 5C6RA 1V89A 5JHGA 2FJLA 2AL6A 2RGNB 2UZRA 3HSAA 1WJ1A 4MY6A 5C79A 5KCVA 5J3QA 3ULBA 2I1JA 4IAPA 5DI9B 2JP2A 5D27A 4QJ5B 3FEHA 1OY2A 3P7ZA 4DIXA 5M4YB 1DBHA 2GCJA 4K17A 1FGZA 4HAZB 4YONA 5JP4A 2YS5A 1FAOA 2CY5A 4TKNA 3A58A 3SUZA 1X1FA 2ZPYA 2IFSA 2KUQA 2LYDA 3KSYA 4MT7A 2GCLA 5I2MA 1Q67A 5C5BB 2DKQA 4HB2B 4D0NB 3D8EA 2P0FA 1K5GB 1WVHA 1XODA 4PQ0A 2Z0PA 2M38A 1U5GA 1J19A 3G9WA 1M7EA 2MWNB 1FGYA 3KZ1A 3B77A 1IRSA 2K8EA 2FJUB 5JHHA 3AU4A 3NSUA 3ZVRA 1Y5OA 1DDMA 1BWNA 2XQNM 2I1KA 2D9WA 4CHMA 2OTXA 1OMWA 2LULA 2W2XD 2LOXA 3PVUA 2YSZA 4P7IA 2Z0QA 1ZC3B 1PMSA 2ROZB 1H10A 1XKEA 2ZKMX 4HB0B 2KUPA 1BTNA 3LJUX 3ODXA 5IRSA 1NI2A 2QKMA 4WSFA 3AU5A 4GNKB 1FOEA 3D8DA 2NZ8B 3HIEA 1UNQA 1UNPA 2DX1A 4KAXB 3N7CA 2YRYA 4HB3B 2Y7BA 3KRWA 2EMTA 5DIFB 3NWFA 1T77A 4EMOA 2J0KA 5C16A 1H4RA 5CLLB 2P0DA 2W2XC 2RUKB 4L6EA 4GMVA 4HB4B 2Z59A 5J3TA 2GS0A 2ADZA 3T06A 1KI1B 3PSCA 1EF1A 4KHBA 1ISNA 5FI1A 4B6HA 4GZUA 5EFXA 2COAA 1UEFA 2J0JA 2DX5A 4ZRJA 2COCA 5JLJB 1DDVA 3HQCA 5GOWB 4Z2MB 1MAIA 3WA0A 1V88A 2Z13A 1FHOA 4HAWB 3P6AA 1MIZB 2RRFA 4MK0A 2YF0A 1X1GA 3FSSA 3X23A 1GC7A 4A6FA 3MDBC 1FHXA 5HE3A 4KHAA 1KZ7A 3V5WA 4WJ7A 1LW3A 1I7AA 1ZSQA 1P6SA 4HAUB 1V61A 3DCXA 2EC1A 2OQBA 2VKIA 2Z4DA 2NMBA 2PZ1A 2R2YA 3TO1A 2E2XA 4A5KA 4ZRIA 2Z14A 4A6KA 1ZC4B 3TW1A 4HHVA 3VOQA 3ULCA 5D3VA 2W2WA 2IYBA 3AJ4A 1WJMA 3CXBB 1W1GA 2D4QA 2MFQA 4F7GA 4OT1A 2GJYA 2GUMA 2ELAA 2D2QA 2M14A 3ZDTA 1PLSA 2Q13A 4OSNA 4K2PA 4Y94A 3PZDA 2V76A 2NBVA 1RRPB 1UNRA 2DN6A 3DXDA 1P5TA 1DROA 4GPTB 4YL8A 3PP2A 1AQCA 3D8FA 3VIAA 2DHKA 3QIJA 2DTCA 1SGHA 2VRWB 1SHCA 2COFA 2J0MA 1GG3A 4HDOA 4HDQA 2YT2A 4QJ3B 1MK9B 2D9XA 2ROVA 2HTHB 4GMXB 2L2IA 2DHJA 2UZSA 1QC6A 2YVCA 1U5EA 1NTYA 3M1IB 2L1CA 1WG7A 1W1HA 3BINA 2UVMA 1UPQA 2DHIA 2DFKA 3WYFB 1V5PA 2X18A 2K2UA 2KIEA 2R09A 3NWDA 1ZM0A 2P0HA 5I2SA 3O96A 3GYPA 3TCAA 4KHBB 2RVBB 1EAZA 4HAYB 4K81A 3OHMB 1X86A 2D11A 2R0DA 3NW8A 4L1RA 1U27A 1V5MA 2I5FA 5D3WA 1RJ2A 1EGXA 1WGQA 3A8QA 5DH9B 2LKOA 1X11A 3TVVA 3OANA 3RCPA 3TFMA 2K00A 3CIKA 2LOZA 1MI1A 1MIXA 5FI0A 4A6FB 1DYNA 1XD4A 1MPHA 2YT1A 5DHAB 2ELBA 4GN1A 4CSQA 2D9YA 5D3YA 3BJIA 4EJNA 4C0AA 2QKLA 3ODOA 3NWAA 2KR0A 3SNHA 2D9ZA 2DLWA 3MPXA 3KY9A 2CY4A 4HAXB 2HE7A 1B55A 3SV1A 1ZVRA 2MKRA 4PNKA 1X05A 4KHOA 5KQ4A 1FB8A 4CHJA 1NU2A 2G35A 2KGXB 4GXBA 2Y8FA 1AWEA 5KQ1A 2P8VA 3U8ZA 1PFJA 3PVWA 2Y8GA 2DYNA 4QJ4B 3PVLA 1BAKA 4DXAB 4KVGB 2AEHA 4Z2NA 2I5CA 2YT0A 3QBVB 1ZYIA 2Z0OA 4F7HA 5C5BA 5CLQB 4ZRKA 2H7EA 2EMSA 1FHWA 4EKUA 3UZTA 2N0YA 1P3RA 1OQNA 2DA0A 2EJ8A 1N3HA 3ODWA 2K49A 2RLOA 1UPRA 2LG1A 4NY0A 1WI1A 1M7RA 4DX90 5HE1A 2YS1A 1DDWA 5J3YA 1U5DA 3IVFA 3PEGA 1K5DB 1W1DA 5LOPB 5HE2A 3PG7A 1TXDA 2YS3A 4D6WA 3HW2B 2MDXA 2N23A 5DHFB 3U12A 1NTVA 5L81A 2J59M 1Y19B 2KIGA 2H7DA 4WVFB 4GOUA 4F7UP 2CODA 4IFSA 4XWXA 2RSGA 4HATB 4HAVB 5HE0A 2K2JA 1V5UA 4BBKA 4NSWA 1U29A 1GC6A 3ML4A 4H8SA 4DX8A 5LG4B 1QQGA 2D10A 3DXEA 1WGUA 1BTKA 1I2HA
chains in the Genus database with same CATH topology
3U7DA 1EVHA 3SO6A 4DBBA 2CRFA 3SYXA 2DYQA 4K2OA 4TYZA 1TJ6A 1KZGA 3F5RA 1U5FA 1U2BA 3KRXA 3HK0A 1LB1A 3FM8C 2KCJA 3GYOA 4A6HA 5D3XA 1XCGA 3DXCA 3F0WA 2D9VA 3QWMA 2CAYA 2BCJA 2VSZA 2DKPA 4IOYX 3A8PA 1MK7B 3A98B 1J0WA 2RNRB 1MKEA 4CYEA 1TQZA 1Z87A 1E5WA 1XX0A 1XR0B 5LONB 5C6RA 1V89A 5JHGA 2FJLA 2AL6A 2RGNB 2UZRA 4MY6A 1WJ1A 5C79A 5KCVA 5J3QA 3ULBA 2I1JA 4IAPA 5DI9B 2JP2A 5D27A 3FEHA 1OY2A 3P7ZA 1DBHA 2GCJA 4K17A 1FGZA 4HAZB 4YONA 5JP4A 2YS5A 1FAOA 2CY5A 4TKNA 3SUZA 1X1FA 3KSYA 2ZPYA 2IFSA 2LYDA 4MT7A 2GCLA 1Q67A 5C5BB 2DKQA 4HB2B 4D0NB 3D8EA 2P0FA 1K5GB 1WVHA 1XODA 4PQ0A 2Z0PA 2M38A 1U5GA 1J19A 3G9WA 1M7EA 2MWNB 1FGYA 3KZ1A 1IRSA 5JHHA 3AU4A 3NSUA 3ZVRA 1Y5OA 1DDMA 1BWNA 2XQNM 2I1KA 2D9WA 4CHMA 2OTXA 1OMWA 2LULA 2W2XD 2LOXA 3PVUA 2YSZA 4P7IA 2Z0QA 1ZC3B 1PMSA 2ROZB 1H10A 1XKEA 4HB0B 2KUPA 1BTNA 3LJUX 3ODXA 1NI2A 2QKMA 4WSFA 3AU5A 1FOEA 3D8DA 2NZ8B 1UNQA 1UNPA 2DX1A 4KAXB 3N7CA 2YRYA 4HB3B 2Y7BA 3KRWA 2EMTA 5DIFB 4EMOA 2J0KA 5C16A 1H4RA 5CLLB 2P0DA 2W2XC 2RUKB 4L6EA 4GMVA 4HB4B 5J3TA 2GS0A 2ADZA 3T06A 1KI1B 3PSCA 1EF1A 1ISNA 5FI1A 4B6HA 4GZUA 5EFXA 2COAA 1UEFA 2J0JA 2DX5A 4ZRJA 2COCA 5JLJB 1DDVA 3HQCA 5GOWB 4Z2MB 1MAIA 3WA0A 1V88A 1FHOA 4HAWB 3P6AA 1MIZB 4MK0A 2YF0A 1X1GA 3FSSA 3X23A 1GC7A 4A6FA 3MDBC 1FHXA 5HE3A 4KHAA 1KZ7A 3V5WA 4WJ7A 1LW3A 1I7AA 1ZSQA 1P6SA 4HAUB 1V61A 2EC1A 2OQBA 2VKIA 2NMBA 2PZ1A 3TO1A 2E2XA 4A5KA 4ZRIA 4A6KA 1ZC4B 3TW1A 4HHVA 3VOQA 3ULCA 5D3VA 2W2WA 2IYBA 3AJ4A 1WJMA 3CXBB 1W1GA 2D4QA 2MFQA 4F7GA 2GJYA 2ELAA 2D2QA 2M14A 3ZDTA 1PLSA 2Q13A 4K2PA 4Y94A 3PZDA 2V76A 1RRPB 1UNRA 2DN6A 3DXDA 1P5TA 1DROA 4GPTB 4YL8A 3PP2A 1AQCA 3D8FA 3VIAA 2DHKA 3QIJA 2DTCA 1SGHA 2VRWB 1SHCA 2COFA 2J0MA 1GG3A 4HDOA 4HDQA 1MK9B 2D9XA 2ROVA 2HTHB 4GMXB 2L2IA 2DHJA 2UZSA 1QC6A 2YVCA 1U5EA 1NTYA 3M1IB 2L1CA 1WG7A 1W1HA 3BINA 2UVMA 1UPQA 2DHIA 2DFKA 3WYFB 1V5PA 2X18A 2K2UA 2R09A 1ZM0A 2P0HA 3O96A 3GYPA 3TCAA 4KHBB 2RVBB 1EAZA 4HAYB 4K81A 1X86A 2D11A 2R0DA 1U27A 1V5MA 2I5FA 5D3WA 1RJ2A 1EGXA 1WGQA 3A8QA 5DH9B 2LKOA 1X11A 3TVVA 3OANA 3RCPA 3TFMA 2K00A 3CIKA 2LOZA 1MIXA 5FI0A 4A6FB 1DYNA 1XD4A 1MPHA 2YT1A 5DHAB 2ELBA 4GN1A 2D9YA 5D3YA 3BJIA 4EJNA 4C0AA 2QKLA 3ODOA 3SNHA 2D9ZA 2DLWA 3MPXA 3KY9A 2CY4A 4HAXB 2HE7A 1B55A 3SV1A 1ZVRA 2MKRA 4PNKA 1X05A 4KHOA 5KQ4A 1FB8A 4CHJA 1NU2A 2G35A 2KGXB 4GXBA 2Y8FA 1AWEA 5KQ1A 2P8VA 3U8ZA 1PFJA 3PVWA 2Y8GA 2DYNA 3PVLA 1BAKA 4DXAB 4KVGB 2AEHA 4Z2NA 2I5CA 2YT0A 3QBVB 2Z0OA 4F7HA 5C5BA 5CLQB 4ZRKA 2H7EA 2EMSA 1FHWA 4EKUA 3UZTA 2N0YA 1P3RA 1OQNA 2DA0A 2EJ8A 1N3HA 3ODWA 2RLOA 1UPRA 2LG1A 4NY0A 1WI1A 1M7RA 4DX90 5HE1A 2YS1A 1DDWA 5J3YA 1U5DA 3IVFA 3PEGA 1K5DB 1W1DA 5LOPB 5HE2A 3PG7A 1TXDA 2YS3A 3HW2B 2MDXA 2N23A 5DHFB 1NTVA 5L81A 2J59M 1Y19B 2H7DA 4WVFB 4F7UP 2CODA 4IFSA 4XWXA 2RSGA 4HATB 4HAVB 5HE0A 2K2JA 1V5UA 4BBKA 4NSWA 1U29A 1GC6A 3ML4A 4H8SA 4DX8A 1QQGA 2D10A 3DXEA 1WGUA 1BTKA 1I2HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3U7D A;  1EVH A;  3SO6 A;  4DBB A;  2CRF A;  3SYX A;  2DYQ A;  4K2O A;  4TYZ A;  1TJ6 A;  1KZG A;  3F5R A;  1U5F A;  1U2B A;  3KRX A;  3HK0 A;  1LB1 A;  3FM8 C;  2KCJ A;  3GYO A;  4A6H A;  5D3X A;  1XCG A;  3DXC A;  3F0W A;  2D9V A;  3QWM A;  2CAY A;  2BCJ A;  2VSZ A;  2DKP A;  4IOY X;  3A8P A;  1MK7 B;  3A98 B;  1J0W A;  2RNR B;  1MKE A;  4CYE A;  1TQZ A;  1Z87 A;  1E5W A;  1XX0 A;  1XR0 B;  5LON B;  5C6R A;  1V89 A;  5JHG A;  2FJL A;  2AL6 A;  2RGN B;  2UZR A;  4MY6 A;  1WJ1 A;  5C79 A;  5KCV A;  5J3Q A;  3ULB A;  2I1J A;  4IAP A;  5DI9 B;  2JP2 A;  5D27 A;  3FEH A;  1OY2 A;  3P7Z A;  1DBH A;  2GCJ A;  4K17 A;  1FGZ A;  4HAZ B;  4YON A;  5JP4 A;  2YS5 A;  1FAO A;  2CY5 A;  4TKN A;  3SUZ A;  1X1F A;  3KSY A;  2ZPY A;  2IFS A;  2LYD A;  4MT7 A;  2GCL A;  1Q67 A;  5C5B B;  2DKQ A;  4HB2 B;  4D0N B;  3D8E A;  2P0F A;  1K5G B;  1WVH A;  1XOD A;  4PQ0 A;  2Z0P A;  2M38 A;  1U5G A;  1J19 A;  3G9W A;  1M7E A;  2MWN B;  1FGY A;  3KZ1 A;  1IRS A;  5JHH A;  3AU4 A;  3NSU A;  3ZVR A;  1Y5O A;  1DDM A;  1BWN A;  2XQN M;  2I1K A;  2D9W A;  4CHM A;  2OTX A;  1OMW A;  2LUL A;  2W2X D;  2LOX A;  3PVU A;  2YSZ A;  4P7I A;  2Z0Q A;  1ZC3 B;  1PMS A;  2ROZ B;  1H10 A;  1XKE A;  4HB0 B;  2KUP A;  1BTN A;  3LJU X;  3ODX A;  1NI2 A;  2QKM A;  4WSF A;  3AU5 A;  1FOE A;  3D8D A;  2NZ8 B;  1UNQ A;  1UNP A;  2DX1 A;  4KAX B;  3N7C A;  2YRY A;  4HB3 B;  2Y7B A;  3KRW A;  2EMT A;  5DIF B;  4EMO A;  2J0K A;  5C16 A;  1H4R A;  5CLL B;  2P0D A;  2W2X C;  2RUK B;  4L6E A;  4GMV A;  4HB4 B;  5J3T A;  2GS0 A;  2ADZ A;  3T06 A;  1KI1 B;  3PSC A;  1EF1 A;  1ISN A;  5FI1 A;  4B6H A;  4GZU A;  5EFX A;  2COA A;  1UEF A;  2J0J A;  2DX5 A;  4ZRJ A;  2COC A;  5JLJ B;  1DDV A;  3HQC A;  5GOW B;  4Z2M B;  1MAI A;  3WA0 A;  1V88 A;  1FHO A;  4HAW B;  3P6A A;  1MIZ B;  4MK0 A;  2YF0 A;  1X1G A;  3FSS A;  3X23 A;  1GC7 A;  4A6F A;  3MDB C;  1FHX A;  5HE3 A;  4KHA A;  1KZ7 A;  3V5W A;  4WJ7 A;  1LW3 A;  1I7A A;  1ZSQ A;  1P6S A;  4HAU B;  1V61 A;  2EC1 A;  2OQB A;  2VKI A;  2NMB A;  2PZ1 A;  3TO1 A;  2E2X A;  4A5K A;  4ZRI A;  4A6K A;  1ZC4 B;  3TW1 A;  4HHV A;  3VOQ A;  3ULC A;  5D3V A;  2W2W A;  2IYB A;  3AJ4 A;  1WJM A;  3CXB B;  1W1G A;  2D4Q A;  2MFQ A;  4F7G A;  2GJY A;  2ELA A;  2D2Q A;  2M14 A;  3ZDT A;  1PLS A;  2Q13 A;  4K2P A;  4Y94 A;  3PZD A;  2V76 A;  1RRP B;  1UNR A;  2DN6 A;  3DXD A;  1P5T A;  1DRO A;  4GPT B;  4YL8 A;  3PP2 A;  1AQC A;  3D8F A;  3VIA A;  2DHK A;  3QIJ A;  2DTC A;  1SGH A;  2VRW B;  1SHC A;  2COF A;  2J0M A;  1GG3 A;  4HDO A;  4HDQ A;  1MK9 B;  2D9X A;  2ROV A;  2HTH B;  4GMX B;  2L2I A;  2DHJ A;  2UZS A;  1QC6 A;  2YVC A;  1U5E A;  1NTY A;  3M1I B;  2L1C A;  1WG7 A;  1W1H A;  3BIN A;  2UVM A;  1UPQ A;  2DHI A;  2DFK A;  3WYF B;  1V5P A;  2X18 A;  2K2U A;  2R09 A;  1ZM0 A;  2P0H A;  3O96 A;  3GYP A;  3TCA A;  4KHB B;  2RVB B;  1EAZ A;  4HAY B;  4K81 A;  1X86 A;  2D11 A;  2R0D A;  1U27 A;  1V5M A;  2I5F A;  5D3W A;  1RJ2 A;  1EGX A;  1WGQ A;  3A8Q A;  5DH9 B;  2LKO A;  1X11 A;  3TVV A;  3OAN A;  3RCP A;  3TFM A;  2K00 A;  3CIK A;  2LOZ A;  1MIX A;  5FI0 A;  4A6F B;  1DYN A;  1XD4 A;  1MPH A;  2YT1 A;  5DHA B;  2ELB A;  4GN1 A;  2D9Y A;  5D3Y A;  3BJI A;  4EJN A;  4C0A A;  2QKL A;  3ODO A;  3SNH A;  2D9Z A;  2DLW A;  3MPX A;  3KY9 A;  2CY4 A;  4HAX B;  2HE7 A;  1B55 A;  3SV1 A;  1ZVR A;  2MKR A;  4PNK A;  1X05 A;  4KHO A;  5KQ4 A;  1FB8 A;  4CHJ A;  1NU2 A;  2G35 A;  2KGX B;  4GXB A;  2Y8F A;  1AWE A;  5KQ1 A;  2P8V A;  3U8Z A;  1PFJ A;  3PVW A;  2Y8G A;  2DYN A;  3PVL A;  1BAK A;  4DXA B;  4KVG B;  2AEH A;  4Z2N A;  2I5C A;  2YT0 A;  3QBV B;  2Z0O A;  4F7H A;  5C5B A;  5CLQ B;  4ZRK A;  2H7E A;  2EMS A;  1FHW A;  4EKU A;  3UZT A;  2N0Y A;  1P3R A;  1OQN A;  2DA0 A;  2EJ8 A;  1N3H A;  3ODW A;  2RLO A;  1UPR A;  2LG1 A;  4NY0 A;  1WI1 A;  1M7R A;  4DX9 0;  5HE1 A;  2YS1 A;  1DDW A;  5J3Y A;  1U5D A;  3IVF A;  3PEG A;  1K5D B;  1W1D A;  5LOP B;  5HE2 A;  3PG7 A;  1TXD A;  2YS3 A;  3HW2 B;  2MDX A;  2N23 A;  5DHF B;  1NTV A;  5L81 A;  2J59 M;  1Y19 B;  2H7D A;  4WVF B;  4F7U P;  2COD A;  4IFS A;  4XWX A;  2RSG A;  4HAT B;  4HAV B;  5HE0 A;  2K2J A;  1V5U A;  4BBK A;  4NSW A;  1U29 A;  1GC6 A;  3ML4 A;  4H8S A;  4DX8 A;  1QQG A;  2D10 A;  3DXE A;  1WGU A;  1BTK A;  1I2H A; 
#chains in the Genus database with same CATH topology
 3U7D A;  1EVH A;  3SO6 A;  4DBB A;  2CRF A;  3SYX A;  2DYQ A;  4K2O A;  4TYZ A;  1TJ6 A;  1KZG A;  3F5R A;  1U5F A;  1U2B A;  3FVC A;  3KRX A;  3HK0 A;  1LB1 A;  3FM8 C;  2KCJ A;  3GYO A;  4A6H A;  5D3X A;  1XCG A;  3DXC A;  3F0W A;  4QXA B;  2D9V A;  3QWM A;  2CAY A;  2BCJ A;  2VSZ A;  2DKP A;  4IOY X;  3A8P A;  1MK7 B;  3A98 B;  1J0W A;  2RNR B;  1MKE A;  4CYE A;  1TQZ A;  1Z87 A;  1E5W A;  1XX0 A;  1XR0 B;  4HSI A;  5LON B;  5C6R A;  1V89 A;  5JHG A;  2FJL A;  2AL6 A;  2RGN B;  2UZR A;  3HSA A;  1WJ1 A;  4MY6 A;  5C79 A;  5KCV A;  5J3Q A;  3ULB A;  2I1J A;  4IAP A;  5DI9 B;  2JP2 A;  5D27 A;  4QJ5 B;  3FEH A;  1OY2 A;  3P7Z A;  4DIX A;  5M4Y B;  1DBH A;  2GCJ A;  4K17 A;  1FGZ A;  4HAZ B;  4YON A;  5JP4 A;  2YS5 A;  1FAO A;  2CY5 A;  4TKN A;  3A58 A;  3SUZ A;  1X1F A;  2ZPY A;  2IFS A;  2KUQ A;  2LYD A;  3KSY A;  4MT7 A;  2GCL A;  5I2M A;  1Q67 A;  5C5B B;  2DKQ A;  4HB2 B;  4D0N B;  3D8E A;  2P0F A;  1K5G B;  1WVH A;  1XOD A;  4PQ0 A;  2Z0P A;  2M38 A;  1U5G A;  1J19 A;  3G9W A;  1M7E A;  2MWN B;  1FGY A;  3KZ1 A;  3B77 A;  1IRS A;  2K8E A;  2FJU B;  5JHH A;  3AU4 A;  3NSU A;  3ZVR A;  1Y5O A;  1DDM A;  1BWN A;  2XQN M;  2I1K A;  2D9W A;  4CHM A;  2OTX A;  1OMW A;  2LUL A;  2W2X D;  2LOX A;  3PVU A;  2YSZ A;  4P7I A;  2Z0Q A;  1ZC3 B;  1PMS A;  2ROZ B;  1H10 A;  1XKE A;  2ZKM X;  4HB0 B;  2KUP A;  1BTN A;  3LJU X;  3ODX A;  5IRS A;  1NI2 A;  2QKM A;  4WSF A;  3AU5 A;  4GNK B;  1FOE A;  3D8D A;  2NZ8 B;  3HIE A;  1UNQ A;  1UNP A;  2DX1 A;  4KAX B;  3N7C A;  2YRY A;  4HB3 B;  2Y7B A;  3KRW A;  2EMT A;  5DIF B;  3NWF A;  1T77 A;  4EMO A;  2J0K A;  5C16 A;  1H4R A;  5CLL B;  2P0D A;  2W2X C;  2RUK B;  4L6E A;  4GMV A;  4HB4 B;  2Z59 A;  5J3T A;  2GS0 A;  2ADZ A;  3T06 A;  1KI1 B;  3PSC A;  1EF1 A;  4KHB A;  1ISN A;  5FI1 A;  4B6H A;  4GZU A;  5EFX A;  2COA A;  1UEF A;  2J0J A;  2DX5 A;  4ZRJ A;  2COC A;  5JLJ B;  1DDV A;  3HQC A;  5GOW B;  4Z2M B;  1MAI A;  3WA0 A;  1V88 A;  2Z13 A;  1FHO A;  4HAW B;  3P6A A;  1MIZ B;  2RRF A;  4MK0 A;  2YF0 A;  1X1G A;  3FSS A;  3X23 A;  1GC7 A;  4A6F A;  3MDB C;  1FHX A;  5HE3 A;  4KHA A;  1KZ7 A;  3V5W A;  4WJ7 A;  1LW3 A;  1I7A A;  1ZSQ A;  1P6S A;  4HAU B;  1V61 A;  3DCX A;  2EC1 A;  2OQB A;  2VKI A;  2Z4D A;  2NMB A;  2PZ1 A;  2R2Y A;  3TO1 A;  2E2X A;  4A5K A;  4ZRI A;  2Z14 A;  4A6K A;  1ZC4 B;  3TW1 A;  4HHV A;  3VOQ A;  3ULC A;  5D3V A;  2W2W A;  2IYB A;  3AJ4 A;  1WJM A;  3CXB B;  1W1G A;  2D4Q A;  2MFQ A;  4F7G A;  4OT1 A;  2GJY A;  2GUM A;  2ELA A;  2D2Q A;  2M14 A;  3ZDT A;  1PLS A;  2Q13 A;  4OSN A;  4K2P A;  4Y94 A;  3PZD A;  2V76 A;  2NBV A;  1RRP B;  1UNR A;  2DN6 A;  3DXD A;  1P5T A;  1DRO A;  4GPT B;  4YL8 A;  3PP2 A;  1AQC A;  3D8F A;  3VIA A;  2DHK A;  3QIJ A;  2DTC A;  1SGH A;  2VRW B;  1SHC A;  2COF A;  2J0M A;  1GG3 A;  4HDO A;  4HDQ A;  2YT2 A;  4QJ3 B;  1MK9 B;  2D9X A;  2ROV A;  2HTH B;  4GMX B;  2L2I A;  2DHJ A;  2UZS A;  1QC6 A;  2YVC A;  1U5E A;  1NTY A;  3M1I B;  2L1C A;  1WG7 A;  1W1H A;  3BIN A;  2UVM A;  1UPQ A;  2DHI A;  2DFK A;  3WYF B;  1V5P A;  2X18 A;  2K2U A;  2KIE A;  2R09 A;  3NWD A;  1ZM0 A;  2P0H A;  5I2S A;  3O96 A;  3GYP A;  3TCA A;  4KHB B;  2RVB B;  1EAZ A;  4HAY B;  4K81 A;  3OHM B;  1X86 A;  2D11 A;  2R0D A;  3NW8 A;  4L1R A;  1U27 A;  1V5M A;  2I5F A;  5D3W A;  1RJ2 A;  1EGX A;  1WGQ A;  3A8Q A;  5DH9 B;  2LKO A;  1X11 A;  3TVV A;  3OAN A;  3RCP A;  3TFM A;  2K00 A;  3CIK A;  2LOZ A;  1MI1 A;  1MIX A;  5FI0 A;  4A6F B;  1DYN A;  1XD4 A;  1MPH A;  2YT1 A;  5DHA B;  2ELB A;  4GN1 A;  4CSQ A;  2D9Y A;  5D3Y A;  3BJI A;  4EJN A;  4C0A A;  2QKL A;  3ODO A;  3NWA A;  2KR0 A;  3SNH A;  2D9Z A;  2DLW A;  3MPX A;  3KY9 A;  2CY4 A;  4HAX B;  2HE7 A;  1B55 A;  3SV1 A;  1ZVR A;  2MKR A;  4PNK A;  1X05 A;  4KHO A;  5KQ4 A;  1FB8 A;  4CHJ A;  1NU2 A;  2G35 A;  2KGX B;  4GXB A;  2Y8F A;  1AWE A;  5KQ1 A;  2P8V A;  3U8Z A;  1PFJ A;  3PVW A;  2Y8G A;  2DYN A;  4QJ4 B;  3PVL A;  1BAK A;  4DXA B;  4KVG B;  2AEH A;  4Z2N A;  2I5C A;  2YT0 A;  3QBV B;  1ZYI A;  2Z0O A;  4F7H A;  5C5B A;  5CLQ B;  4ZRK A;  2H7E A;  2EMS A;  1FHW A;  4EKU A;  3UZT A;  2N0Y A;  1P3R A;  1OQN A;  2DA0 A;  2EJ8 A;  1N3H A;  3ODW A;  2K49 A;  2RLO A;  1UPR A;  2LG1 A;  4NY0 A;  1WI1 A;  1M7R A;  4DX9 0;  5HE1 A;  2YS1 A;  1DDW A;  5J3Y A;  1U5D A;  3IVF A;  3PEG A;  1K5D B;  1W1D A;  5LOP B;  5HE2 A;  3PG7 A;  1TXD A;  2YS3 A;  4D6W A;  3HW2 B;  2MDX A;  2N23 A;  5DHF B;  3U12 A;  1NTV A;  5L81 A;  2J59 M;  1Y19 B;  2KIG A;  2H7D A;  4WVF B;  4GOU A;  4F7U P;  2COD A;  4IFS A;  4XWX A;  2RSG A;  4HAT B;  4HAV B;  5HE0 A;  2K2J A;  1V5U A;  4BBK A;  4NSW A;  1U29 A;  1GC6 A;  3ML4 A;  4H8S A;  4DX8 A;  5LG4 B;  1QQG A;  2D10 A;  3DXE A;  1WGU A;  1BTK A;  1I2H A; 
#chains in the Genus database with same CATH homology
 3U7D A;  1EVH A;  3SO6 A;  4DBB A;  2CRF A;  3SYX A;  2DYQ A;  4K2O A;  4TYZ A;  1TJ6 A;  1KZG A;  3F5R A;  1U5F A;  1U2B A;  3KRX A;  3HK0 A;  1LB1 A;  3FM8 C;  2KCJ A;  3GYO A;  4A6H A;  5D3X A;  1XCG A;  3DXC A;  3F0W A;  2D9V A;  3QWM A;  2CAY A;  2BCJ A;  2VSZ A;  2DKP A;  4IOY X;  3A8P A;  1MK7 B;  3A98 B;  1J0W A;  2RNR B;  1MKE A;  4CYE A;  1TQZ A;  1Z87 A;  1E5W A;  1XX0 A;  1XR0 B;  5LON B;  5C6R A;  1V89 A;  5JHG A;  2FJL A;  2AL6 A;  2RGN B;  2UZR A;  4MY6 A;  1WJ1 A;  5C79 A;  5KCV A;  5J3Q A;  3ULB A;  2I1J A;  4IAP A;  5DI9 B;  2JP2 A;  5D27 A;  3FEH A;  1OY2 A;  3P7Z A;  1DBH A;  2GCJ A;  4K17 A;  1FGZ A;  4HAZ B;  4YON A;  5JP4 A;  2YS5 A;  1FAO A;  2CY5 A;  4TKN A;  3SUZ A;  1X1F A;  3KSY A;  2ZPY A;  2IFS A;  2LYD A;  4MT7 A;  2GCL A;  1Q67 A;  5C5B B;  2DKQ A;  4HB2 B;  4D0N B;  3D8E A;  2P0F A;  1K5G B;  1WVH A;  1XOD A;  4PQ0 A;  2Z0P A;  2M38 A;  1U5G A;  1J19 A;  3G9W A;  1M7E A;  2MWN B;  1FGY A;  3KZ1 A;  1IRS A;  5JHH A;  3AU4 A;  3NSU A;  3ZVR A;  1Y5O A;  1DDM A;  1BWN A;  2XQN M;  2I1K A;  2D9W A;  4CHM A;  2OTX A;  1OMW A;  2LUL A;  2W2X D;  2LOX A;  3PVU A;  2YSZ A;  4P7I A;  2Z0Q A;  1ZC3 B;  1PMS A;  2ROZ B;  1H10 A;  1XKE A;  4HB0 B;  2KUP A;  1BTN A;  3LJU X;  3ODX A;  1NI2 A;  2QKM A;  4WSF A;  3AU5 A;  1FOE A;  3D8D A;  2NZ8 B;  1UNQ A;  1UNP A;  2DX1 A;  4KAX B;  3N7C A;  2YRY A;  4HB3 B;  2Y7B A;  3KRW A;  2EMT A;  5DIF B;  4EMO A;  2J0K A;  5C16 A;  1H4R A;  5CLL B;  2P0D A;  2W2X C;  2RUK B;  4L6E A;  4GMV A;  4HB4 B;  5J3T A;  2GS0 A;  2ADZ A;  3T06 A;  1KI1 B;  3PSC A;  1EF1 A;  1ISN A;  5FI1 A;  4B6H A;  4GZU A;  5EFX A;  2COA A;  1UEF A;  2J0J A;  2DX5 A;  4ZRJ A;  2COC A;  5JLJ B;  1DDV A;  3HQC A;  5GOW B;  4Z2M B;  1MAI A;  3WA0 A;  1V88 A;  1FHO A;  4HAW B;  3P6A A;  1MIZ B;  4MK0 A;  2YF0 A;  1X1G A;  3FSS A;  3X23 A;  1GC7 A;  4A6F A;  3MDB C;  1FHX A;  5HE3 A;  4KHA A;  1KZ7 A;  3V5W A;  4WJ7 A;  1LW3 A;  1I7A A;  1ZSQ A;  1P6S A;  4HAU B;  1V61 A;  2EC1 A;  2OQB A;  2VKI A;  2NMB A;  2PZ1 A;  3TO1 A;  2E2X A;  4A5K A;  4ZRI A;  4A6K A;  1ZC4 B;  3TW1 A;  4HHV A;  3VOQ A;  3ULC A;  5D3V A;  2W2W A;  2IYB A;  3AJ4 A;  1WJM A;  3CXB B;  1W1G A;  2D4Q A;  2MFQ A;  4F7G A;  2GJY A;  2ELA A;  2D2Q A;  2M14 A;  3ZDT A;  1PLS A;  2Q13 A;  4K2P A;  4Y94 A;  3PZD A;  2V76 A;  1RRP B;  1UNR A;  2DN6 A;  3DXD A;  1P5T A;  1DRO A;  4GPT B;  4YL8 A;  3PP2 A;  1AQC A;  3D8F A;  3VIA A;  2DHK A;  3QIJ A;  2DTC A;  1SGH A;  2VRW B;  1SHC A;  2COF A;  2J0M A;  1GG3 A;  4HDO A;  4HDQ A;  1MK9 B;  2D9X A;  2ROV A;  2HTH B;  4GMX B;  2L2I A;  2DHJ A;  2UZS A;  1QC6 A;  2YVC A;  1U5E A;  1NTY A;  3M1I B;  2L1C A;  1WG7 A;  1W1H A;  3BIN A;  2UVM A;  1UPQ A;  2DHI A;  2DFK A;  3WYF B;  1V5P A;  2X18 A;  2K2U A;  2R09 A;  1ZM0 A;  2P0H A;  3O96 A;  3GYP A;  3TCA A;  4KHB B;  2RVB B;  1EAZ A;  4HAY B;  4K81 A;  1X86 A;  2D11 A;  2R0D A;  1U27 A;  1V5M A;  2I5F A;  5D3W A;  1RJ2 A;  1EGX A;  1WGQ A;  3A8Q A;  5DH9 B;  2LKO A;  1X11 A;  3TVV A;  3OAN A;  3RCP A;  3TFM A;  2K00 A;  3CIK A;  2LOZ A;  1MIX A;  5FI0 A;  4A6F B;  1DYN A;  1XD4 A;  1MPH A;  2YT1 A;  5DHA B;  2ELB A;  4GN1 A;  2D9Y A;  5D3Y A;  3BJI A;  4EJN A;  4C0A A;  2QKL A;  3ODO A;  3SNH A;  2D9Z A;  2DLW A;  3MPX A;  3KY9 A;  2CY4 A;  4HAX B;  2HE7 A;  1B55 A;  3SV1 A;  1ZVR A;  2MKR A;  4PNK A;  1X05 A;  4KHO A;  5KQ4 A;  1FB8 A;  4CHJ A;  1NU2 A;  2G35 A;  2KGX B;  4GXB A;  2Y8F A;  1AWE A;  5KQ1 A;  2P8V A;  3U8Z A;  1PFJ A;  3PVW A;  2Y8G A;  2DYN A;  3PVL A;  1BAK A;  4DXA B;  4KVG B;  2AEH A;  4Z2N A;  2I5C A;  2YT0 A;  3QBV B;  2Z0O A;  4F7H A;  5C5B A;  5CLQ B;  4ZRK A;  2H7E A;  2EMS A;  1FHW A;  4EKU A;  3UZT A;  2N0Y A;  1P3R A;  1OQN A;  2DA0 A;  2EJ8 A;  1N3H A;  3ODW A;  2RLO A;  1UPR A;  2LG1 A;  4NY0 A;  1WI1 A;  1M7R A;  4DX9 0;  5HE1 A;  2YS1 A;  1DDW A;  5J3Y A;  1U5D A;  3IVF A;  3PEG A;  1K5D B;  1W1D A;  5LOP B;  5HE2 A;  3PG7 A;  1TXD A;  2YS3 A;  3HW2 B;  2MDX A;  2N23 A;  5DHF B;  1NTV A;  5L81 A;  2J59 M;  1Y19 B;  2H7D A;  4WVF B;  4F7U P;  2COD A;  4IFS A;  4XWX A;  2RSG A;  4HAT B;  4HAV B;  5HE0 A;  2K2J A;  1V5U A;  4BBK A;  4NSW A;  1U29 A;  1GC6 A;  3ML4 A;  4H8S A;  4DX8 A;  1QQG A;  2D10 A;  3DXE A;  1WGU A;  1BTK A;  1I2H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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