2UZRA

A transforming mutation in the pleckstrin homology domain of akt1 in cancer (akt1-ph_e17k)
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
118
structure length
113
Chain Sequence
DVAIVKEGWLHKRGKYIKTWRPRYFLLKNDGTFIGYKERPREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
molecule keywords RAC-alpha serine/threonine-protein kinase
total genus 30
structure length 113
sequence length 118
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-05-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 2uzrA00
1B55A 1KZ7A 1ZC4B 2PZ1A 1U5GA 2ADZA 1BWNA 1RRPB 2DYNA 2I5CA 2LKOA 1EGXA 3TO1A 2UVMA 4HATB 2MWNB 3V5WA 1EVHA 1OY2A 4WJ7A 4HDOA 3T06A 4DXAB 4HDQA 3PG7A 1WJ1A 1U2BA 5FI1A 1OMWA 1ISNA 3HQCA 2P0DA 3BJIA 2COAA 3ML4A 2Q13A 2BCJA 4F7GA 3OANA 2YSZA 4A6KA 2VSZA 1BAKA 2EMTA 3AU5A 2K2JA 3DXEA 3F0WA 5C5BA 2D9WA 3IVFA 2XQNM 2N23A 2FJLA 1DROA 5GOWB 3U7DA 1UNQA 2P8VA 4HAXB 2LG1A 2D4QA 3RCPA 2QKMA 3A98B 1RJ2A 2V76A 2IFSA 1PFJA 2COCA 3NSUA 4NSWA 3PP2A 1GG3A 1NTVA 3SO6A 2Y7BA 3HW2B 5DI9B 4GZUA 5HE3A 2DA0A 5C6RA 4HAVB 2YRYA 1KI1B 1E5WA 3M1IB 2VKIA 1ZM0A 5HE1A 4ZRKA 4HAWB 2RLOA 5KQ4A 1WVHA 2UZSA 3D8EA 2CODA 2L1CA 3N7CA 1V88A 1NI2A 2YS1A 2DX5A 5L81A 2RNRB 4F7HA 3PVUA 5C16A 3TFMA 1V5PA 3A8PA 3VIAA 5D3VA 1M7EA 2YF0A 2LOZA 4IAPA 4HAYB 2ZPYA 4A6HA 2ELBA 4A5KA 2DKPA 3PVWA 1EF1A 4F7UP 5LONB 3HK0A 3TW1A 2M38A 2ELAA 1U5FA 2NZ8B 3D8DA 3P6AA 4YONA 2DHKA 3PEGA 4WSFA 1TQZA 1Q67A 4KHAA 4L6EA 3X23A 3ZVRA 1U5DA 1I2HA 4EKUA 4GMVA 5KCVA 1QC6A 4B6HA 1P3RA 3ULBA 2D2QA 2LOXA 1X05A 1XD4A 2Y8GA 5JHGA 1FHOA 2DN6A 2P0HA 1AQCA 3QWMA 1FOEA 1LB1A 3P7ZA 2YT1A 1DBHA 2D11A 3ODXA 1PLSA 2HTHB 1QQGA 5LOPB 2ROVA 2OTXA 4CHJA 4K2OA 4MY6A 3AJ4A 2JP2A 1EAZA 1X1GA 5EFXA 2DHJA 1TJ6A 1XR0B 3DXDA 4Z2MB 5CLLB 4GXBA 1Z87A 2KCJA 3ZDTA 2DTCA 1AWEA 1K5GB 3SNHA 1GC7A 3KY9A 3MPXA 2E2XA 1UPRA 2D9VA 1J0WA 4EJNA 3ODOA 2X18A 4WVFB 1MKEA 3DXCA 2DLWA 4PQ0A 1DDVA 4A6FB 2M14A 4GMXB 3UZTA 1X11A 4H8SA 2R0DA 4MT7A 1V5UA 4Y94A 2DX1A 1FHWA 3VOQA 5HE2A 2H7DA 4HAUB 5JLJB 2D10A 3U8ZA 2DYQA 2I5FA 2OQBA 3KSYA 5JHHA 5C5BB 4HB3B 3QIJA 3LJUX 1ZSQA 1W1HA 4IOYX 1X86A 2GCLA 1W1DA 1FGYA 2RUKB 1WGUA 1MK7B 2H7EA 5DIFB 3AU4A 1IRSA 1X1FA 5DH9B 1V61A 2W2XD 4YL8A 4Z2NA 2CY4A 2J0KA 2YS5A 4CHMA 1FGZA 2KGXB 4HB4B 3SUZA 1BTNA 2D9ZA 2P0FA 2Z0PA 1MIZB 1XODA 4BBKA 2RGNB 4DBBA 2DFKA 1GC6A 2KUPA 4DX8A 2Z0QA 2I1KA 1M7RA 1MAIA 1H10A 1FAOA 5CLQB 2AEHA 2EJ8A 3CIKA 4TKNA 5C79A 1SGHA 3O96A 5DHFB 5J3TA 1TXDA 1KZGA 3CXBB 4P7IA 4MK0A 1NTYA 3GYOA 3SYXA 4KHBB 4DX90 1Y5OA 1UNRA 3KRWA 4ZRJA 4D0NB 3SV1A 1UPQA 3FEHA 4IFSA 4KAXB 1H4RA 2W2XC 3WYFB 1OQNA 1U5EA 3BINA 2K00A 1UEFA 1Y19B 1MIXA 5D27A 3TVVA 5FI0A 3F5RA 1FB8A 3TCAA 2HE7A 1V5MA 4XWXA 1PMSA 3ODWA 2GS0A 4EMOA 4HAZB 4GPTB 3ULCA 1U29A 2L2IA 2GJYA 3GYPA 2ROZB 4NY0A 3KRXA 5HE0A 2QKLA 2COFA 5KQ1A 2Z0OA 1P6SA 2AL6A 2D9XA 2EMSA 5D3YA 2LULA 1FHXA 1WG7A 2J59M 2CY5A 1UNPA 1XKEA 2Y8FA 1DYNA 1WGQA 1DDWA 2UZRA 5J3QA 5J3YA 4CYEA 5D3XA 3FSSA 2YVCA 3KZ1A 1K5DB 2MKRA 1I7AA 1ZC3B 2D9YA 3QBVB 4K2PA 5DHAB 4PNKA 4HB0B 4GN1A 4TYZA 2R09A 2CRFA 4A6FA 1J19A 1W1GA 1MK9B 1BTKA 4ZRIA 2LYDA 2W2WA 4K17A 3WA0A 4C0AA 2G35A 1N3HA 2J0JA 2MDXA 1SHCA 3PVLA 1MPHA 1ZVRA 2MFQA 2VRWB 1DDMA 2DKQA 2YT0A 4KHOA 1LW3A 2DHIA 2I1JA 2J0MA 2YS3A 3G9WA 2RSGA 2IYBA 2K2UA 3FM8C 2GCJA 1NU2A 1V89A 1XX0A 3D8FA 1WJMA 2CAYA 2EC1A 4KVGB 3A8QA 4HHVA 3PSCA 1WI1A 2N0YA 5D3WA 3MDBC 4K81A 4HB2B 2RVBB 3PZDA 1P5TA 1U27A 2NMBA 5JP4A 1XCGA
chains in the Genus database with same CATH superfamily
1B55A 1KZ7A 1ZC4B 2PZ1A 1U5GA 2ADZA 1BWNA 1RRPB 2DYNA 2I5CA 2LKOA 1EGXA 4GOUA 3TO1A 2UVMA 4HATB 2MWNB 3V5WA 3B77A 1EVHA 1OY2A 4WJ7A 4HDOA 3T06A 4DXAB 4HDQA 3PG7A 1WJ1A 1U2BA 5FI1A 1OMWA 1ISNA 3HQCA 2Z13A 3NWAA 2P0DA 3BJIA 2COAA 3ML4A 2Q13A 4QXAB 2BCJA 4F7GA 3OANA 2YSZA 4A6KA 2VSZA 4GNKB 1BAKA 2EMTA 3AU5A 2K2JA 3DXEA 3F0WA 5C5BA 2D9WA 3IVFA 2XQNM 2N23A 5M4YB 2FJLA 1DROA 5GOWB 3U7DA 1UNQA 2Z59A 2P8VA 4HAXB 2LG1A 2D4QA 3RCPA 2QKMA 3A98B 1RJ2A 2V76A 2IFSA 1PFJA 2COCA 3NSUA 4NSWA 3PP2A 1GG3A 1NTVA 3SO6A 2KR0A 2Y7BA 3HW2B 5DI9B 4GZUA 3A58A 5HE3A 2DA0A 5C6RA 4HAVB 2KUQA 2YRYA 1KI1B 1E5WA 3M1IB 2VKIA 1ZM0A 5HE1A 2Z4DA 4ZRKA 4HAWB 2RLOA 5KQ4A 1WVHA 2UZSA 3D8EA 2CODA 2L1CA 3N7CA 1V88A 1NI2A 2YS1A 2DX5A 4HSIA 1T77A 2RNRB 2Z14A 4F7HA 5L81A 3PVUA 5C16A 3TFMA 1V5PA 3A8PA 3VIAA 5D3VA 1M7EA 2YF0A 2LOZA 4IAPA 4HAYB 2ZPYA 4A6HA 2ELBA 4A5KA 2DKPA 3PVWA 1EF1A 4F7UP 5LONB 3HK0A 3TW1A 2M38A 2ELAA 1U5FA 2NZ8B 3D8DA 3P6AA 4D6WA 4YONA 2DHKA 1MI1A 3PEGA 4WSFA 1TQZA 1Q67A 4KHAA 4L6EA 3X23A 3ZVRA 1U5DA 1I2HA 4EKUA 4GMVA 5KCVA 1QC6A 3NWDA 4B6HA 1P3RA 3ULBA 2D2QA 2LOXA 1X05A 1XD4A 2Y8GA 5JHGA 1FHOA 2DN6A 1ZYIA 2P0HA 1AQCA 1FOEA 3QWMA 1LB1A 3P7ZA 2YT1A 1DBHA 2D11A 3ODXA 1PLSA 2HTHB 1QQGA 5LOPB 2ROVA 2OTXA 4CHJA 4K2OA 3NWFA 4MY6A 5LG4B 3AJ4A 2JP2A 5I2MA 1EAZA 1X1GA 5EFXA 2DHJA 1TJ6A 1XR0B 3DXDA 4Z2MB 5CLLB 4GXBA 1Z87A 2KCJA 3ZDTA 2DTCA 1AWEA 1K5GB 3DCXA 3SNHA 1GC7A 3KY9A 3MPXA 2E2XA 1UPRA 2D9VA 1J0WA 4EJNA 3ODOA 2X18A 4WVFB 1MKEA 3DXCA 3HSAA 2DLWA 4PQ0A 1DDVA 4A6FB 2M14A 4GMXB 3UZTA 1X11A 4H8SA 2R0DA 4MT7A 1V5UA 3NW8A 4Y94A 2DX1A 1FHWA 3VOQA 5HE2A 4CSQA 2H7DA 4HAUB 5JLJB 2NBVA 2D10A 3U8ZA 2KIEA 2DYQA 2I5FA 2OQBA 3KSYA 5JHHA 2YT2A 5C5BB 4HB3B 3QIJA 3LJUX 1ZSQA 1W1HA 4IOYX 1X86A 2GCLA 2FJUB 1W1DA 1FGYA 2RUKB 1WGUA 1MK7B 2H7EA 5DIFB 3AU4A 1IRSA 1X1FA 5DH9B 1V61A 2W2XD 4YL8A 4Z2NA 2CY4A 2J0KA 2YS5A 4CHMA 1FGZA 2KGXB 4HB4B 3SUZA 1BTNA 2D9ZA 2P0FA 2Z0PA 5IRSA 1MIZB 1XODA 4BBKA 2RGNB 4DBBA 2DFKA 1GC6A 2KUPA 4DX8A 2Z0QA 2I1KA 1M7RA 1MAIA 1H10A 4L1RA 1FAOA 5CLQB 2AEHA 2EJ8A 3CIKA 4TKNA 5C79A 1SGHA 3O96A 5DHFB 5J3TA 1TXDA 1KZGA 3CXBB 4P7IA 3U12A 4MK0A 3FVCA 1NTYA 3GYOA 3SYXA 4KHBB 4DX90 1Y5OA 4QJ4B 1UNRA 3KRWA 4ZRJA 4D0NB 3SV1A 5I2SA 1UPQA 3FEHA 4IFSA 4KAXB 1H4RA 2W2XC 3WYFB 1OQNA 1U5EA 3BINA 2K00A 1UEFA 4QJ3B 1Y19B 1MIXA 5D27A 3TVVA 5FI0A 3F5RA 1FB8A 3TCAA 2HE7A 1V5MA 4XWXA 1PMSA 3ODWA 2GS0A 4EMOA 4HAZB 4GPTB 3ULCA 1U29A 2L2IA 2GJYA 3GYPA 2ROZB 4NY0A 4QJ5B 3KRXA 5HE0A 2QKLA 2COFA 4OT1A 5KQ1A 2Z0OA 1P6SA 2AL6A 2D9XA 2EMSA 5D3YA 2LULA 1FHXA 1WG7A 2J59M 2CY5A 4KHBA 1UNPA 1XKEA 2Y8FA 1DYNA 1WGQA 1DDWA 2R2YA 2UZRA 5J3QA 5J3YA 4CYEA 5D3XA 3FSSA 2GUMA 2YVCA 3KZ1A 1K5DB 2MKRA 1I7AA 1ZC3B 2D9YA 3QBVB 4K2PA 5DHAB 4PNKA 4HB0B 4GN1A 4TYZA 2K8EA 2R09A 2CRFA 4A6FA 1J19A 1W1GA 1MK9B 1BTKA 2KIGA 4ZRIA 2LYDA 2W2WA 4K17A 3WA0A 3OHMB 4C0AA 4DIXA 2G35A 1N3HA 2J0JA 2MDXA 1SHCA 3PVLA 1MPHA 1ZVRA 2MFQA 2VRWB 3HIEA 1DDMA 2DKQA 2YT0A 2K49A 4KHOA 1LW3A 2DHIA 2I1JA 2J0MA 2YS3A 3G9WA 2RSGA 2IYBA 2K2UA 3FM8C 2GCJA 1NU2A 1V89A 1XX0A 2ZKMX 3D8FA 1WJMA 2CAYA 2EC1A 4KVGB 4OSNA 3A8QA 4HHVA 3PSCA 1WI1A 2N0YA 5D3WA 3MDBC 4K81A 4HB2B 2RVBB 3PZDA 1P5TA 2RRFA 1U27A 2NMBA 5JP4A 1XCGA
chains in the Genus database with same CATH topology
1B55A 1KZ7A 1ZC4B 2PZ1A 1U5GA 2ADZA 1BWNA 1RRPB 2DYNA 2I5CA 2LKOA 1EGXA 3TO1A 2UVMA 4HATB 2MWNB 3V5WA 1EVHA 1OY2A 4WJ7A 4HDOA 3T06A 4DXAB 4HDQA 3PG7A 1WJ1A 1U2BA 5FI1A 1OMWA 1ISNA 3HQCA 2P0DA 3BJIA 2COAA 3ML4A 2Q13A 2BCJA 4F7GA 3OANA 2YSZA 4A6KA 2VSZA 1BAKA 2EMTA 3AU5A 2K2JA 3DXEA 3F0WA 5C5BA 2D9WA 3IVFA 2XQNM 2N23A 2FJLA 1DROA 5GOWB 3U7DA 1UNQA 2P8VA 4HAXB 2LG1A 2D4QA 3RCPA 2QKMA 3A98B 1RJ2A 2V76A 2IFSA 1PFJA 2COCA 3NSUA 4NSWA 3PP2A 1GG3A 1NTVA 3SO6A 2Y7BA 3HW2B 5DI9B 4GZUA 5HE3A 2DA0A 5C6RA 4HAVB 2YRYA 1KI1B 1E5WA 3M1IB 2VKIA 1ZM0A 5HE1A 4ZRKA 4HAWB 2RLOA 5KQ4A 1WVHA 2UZSA 3D8EA 2CODA 2L1CA 3N7CA 1V88A 1NI2A 2YS1A 2DX5A 5L81A 2RNRB 4F7HA 3PVUA 5C16A 3TFMA 1V5PA 3A8PA 3VIAA 5D3VA 1M7EA 2YF0A 2LOZA 4IAPA 4HAYB 2ZPYA 4A6HA 2ELBA 4A5KA 2DKPA 3PVWA 1EF1A 4F7UP 5LONB 3HK0A 3TW1A 2M38A 2ELAA 1U5FA 2NZ8B 3D8DA 3P6AA 4YONA 2DHKA 3PEGA 4WSFA 1TQZA 1Q67A 4KHAA 4L6EA 3X23A 3ZVRA 1U5DA 1I2HA 4EKUA 4GMVA 5KCVA 1QC6A 4B6HA 1P3RA 3ULBA 2D2QA 2LOXA 1X05A 1XD4A 2Y8GA 5JHGA 1FHOA 2DN6A 2P0HA 1AQCA 3QWMA 1FOEA 1LB1A 3P7ZA 2YT1A 1DBHA 2D11A 3ODXA 1PLSA 2HTHB 1QQGA 5LOPB 2ROVA 2OTXA 4CHJA 4K2OA 4MY6A 3AJ4A 2JP2A 1EAZA 1X1GA 5EFXA 2DHJA 1TJ6A 1XR0B 3DXDA 4Z2MB 5CLLB 4GXBA 1Z87A 2KCJA 3ZDTA 2DTCA 1AWEA 1K5GB 3SNHA 1GC7A 3KY9A 3MPXA 2E2XA 1UPRA 2D9VA 1J0WA 4EJNA 3ODOA 2X18A 4WVFB 1MKEA 3DXCA 2DLWA 4PQ0A 1DDVA 4A6FB 2M14A 4GMXB 3UZTA 1X11A 4H8SA 2R0DA 4MT7A 1V5UA 4Y94A 2DX1A 1FHWA 3VOQA 5HE2A 2H7DA 4HAUB 5JLJB 2D10A 3U8ZA 2DYQA 2I5FA 2OQBA 3KSYA 5JHHA 5C5BB 4HB3B 3QIJA 3LJUX 1ZSQA 1W1HA 4IOYX 1X86A 2GCLA 1W1DA 1FGYA 2RUKB 1WGUA 1MK7B 2H7EA 5DIFB 3AU4A 1IRSA 1X1FA 5DH9B 1V61A 2W2XD 4YL8A 4Z2NA 2CY4A 2J0KA 2YS5A 4CHMA 1FGZA 2KGXB 4HB4B 3SUZA 1BTNA 2D9ZA 2P0FA 2Z0PA 1MIZB 1XODA 4BBKA 2RGNB 4DBBA 2DFKA 1GC6A 2KUPA 4DX8A 2Z0QA 2I1KA 1M7RA 1MAIA 1H10A 1FAOA 5CLQB 2AEHA 2EJ8A 3CIKA 4TKNA 5C79A 1SGHA 3O96A 5DHFB 5J3TA 1TXDA 1KZGA 3CXBB 4P7IA 4MK0A 1NTYA 3GYOA 3SYXA 4KHBB 4DX90 1Y5OA 1UNRA 3KRWA 4ZRJA 4D0NB 3SV1A 1UPQA 3FEHA 4IFSA 4KAXB 1H4RA 2W2XC 3WYFB 1OQNA 1U5EA 3BINA 2K00A 1UEFA 1Y19B 1MIXA 5D27A 3TVVA 5FI0A 3F5RA 1FB8A 3TCAA 2HE7A 1V5MA 4XWXA 1PMSA 3ODWA 2GS0A 4EMOA 4HAZB 4GPTB 3ULCA 1U29A 2L2IA 2GJYA 3GYPA 2ROZB 4NY0A 3KRXA 5HE0A 2QKLA 2COFA 5KQ1A 2Z0OA 1P6SA 2AL6A 2D9XA 2EMSA 5D3YA 2LULA 1FHXA 1WG7A 2J59M 2CY5A 1UNPA 1XKEA 2Y8FA 1DYNA 1WGQA 1DDWA 2UZRA 5J3QA 5J3YA 4CYEA 5D3XA 3FSSA 2YVCA 3KZ1A 1K5DB 2MKRA 1I7AA 1ZC3B 2D9YA 3QBVB 4K2PA 5DHAB 4PNKA 4HB0B 4GN1A 4TYZA 2R09A 2CRFA 4A6FA 1J19A 1W1GA 1MK9B 1BTKA 4ZRIA 2LYDA 2W2WA 4K17A 3WA0A 4C0AA 2G35A 1N3HA 2J0JA 2MDXA 1SHCA 3PVLA 1MPHA 1ZVRA 2MFQA 2VRWB 1DDMA 2DKQA 2YT0A 4KHOA 1LW3A 2DHIA 2I1JA 2J0MA 2YS3A 3G9WA 2RSGA 2IYBA 2K2UA 3FM8C 2GCJA 1NU2A 1V89A 1XX0A 3D8FA 1WJMA 2CAYA 2EC1A 4KVGB 3A8QA 4HHVA 3PSCA 1WI1A 2N0YA 5D3WA 3MDBC 4K81A 4HB2B 2RVBB 3PZDA 1P5TA 1U27A 2NMBA 5JP4A 1XCGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B55 A;  1KZ7 A;  1ZC4 B;  2PZ1 A;  1U5G A;  2ADZ A;  1BWN A;  1RRP B;  2DYN A;  2I5C A;  2LKO A;  1EGX A;  3TO1 A;  2UVM A;  4HAT B;  2MWN B;  3V5W A;  1EVH A;  1OY2 A;  4WJ7 A;  4HDO A;  3T06 A;  4DXA B;  4HDQ A;  3PG7 A;  1WJ1 A;  1U2B A;  5FI1 A;  1OMW A;  1ISN A;  3HQC A;  2P0D A;  3BJI A;  2COA A;  3ML4 A;  2Q13 A;  2BCJ A;  4F7G A;  3OAN A;  2YSZ A;  4A6K A;  2VSZ A;  1BAK A;  2EMT A;  3AU5 A;  2K2J A;  3DXE A;  3F0W A;  5C5B A;  2D9W A;  3IVF A;  2XQN M;  2N23 A;  2FJL A;  1DRO A;  5GOW B;  3U7D A;  1UNQ A;  2P8V A;  4HAX B;  2LG1 A;  2D4Q A;  3RCP A;  2QKM A;  3A98 B;  1RJ2 A;  2V76 A;  2IFS A;  1PFJ A;  2COC A;  3NSU A;  4NSW A;  3PP2 A;  1GG3 A;  1NTV A;  3SO6 A;  2Y7B A;  3HW2 B;  5DI9 B;  4GZU A;  5HE3 A;  2DA0 A;  5C6R A;  4HAV B;  2YRY A;  1KI1 B;  1E5W A;  3M1I B;  2VKI A;  1ZM0 A;  5HE1 A;  4ZRK A;  4HAW B;  2RLO A;  5KQ4 A;  1WVH A;  2UZS A;  3D8E A;  2COD A;  2L1C A;  3N7C A;  1V88 A;  1NI2 A;  2YS1 A;  2DX5 A;  5L81 A;  2RNR B;  4F7H A;  3PVU A;  5C16 A;  3TFM A;  1V5P A;  3A8P A;  3VIA A;  5D3V A;  1M7E A;  2YF0 A;  2LOZ A;  4IAP A;  4HAY B;  2ZPY A;  4A6H A;  2ELB A;  4A5K A;  2DKP A;  3PVW A;  1EF1 A;  4F7U P;  5LON B;  3HK0 A;  3TW1 A;  2M38 A;  2ELA A;  1U5F A;  2NZ8 B;  3D8D A;  3P6A A;  4YON A;  2DHK A;  3PEG A;  4WSF A;  1TQZ A;  1Q67 A;  4KHA A;  4L6E A;  3X23 A;  3ZVR A;  1U5D A;  1I2H A;  4EKU A;  4GMV A;  5KCV A;  1QC6 A;  4B6H A;  1P3R A;  3ULB A;  2D2Q A;  2LOX A;  1X05 A;  1XD4 A;  2Y8G A;  5JHG A;  1FHO A;  2DN6 A;  2P0H A;  1AQC A;  3QWM A;  1FOE A;  1LB1 A;  3P7Z A;  2YT1 A;  1DBH A;  2D11 A;  3ODX A;  1PLS A;  2HTH B;  1QQG A;  5LOP B;  2ROV A;  2OTX A;  4CHJ A;  4K2O A;  4MY6 A;  3AJ4 A;  2JP2 A;  1EAZ A;  1X1G A;  5EFX A;  2DHJ A;  1TJ6 A;  1XR0 B;  3DXD A;  4Z2M B;  5CLL B;  4GXB A;  1Z87 A;  2KCJ A;  3ZDT A;  2DTC A;  1AWE A;  1K5G B;  3SNH A;  1GC7 A;  3KY9 A;  3MPX A;  2E2X A;  1UPR A;  2D9V A;  1J0W A;  4EJN A;  3ODO A;  2X18 A;  4WVF B;  1MKE A;  3DXC A;  2DLW A;  4PQ0 A;  1DDV A;  4A6F B;  2M14 A;  4GMX B;  3UZT A;  1X11 A;  4H8S A;  2R0D A;  4MT7 A;  1V5U A;  4Y94 A;  2DX1 A;  1FHW A;  3VOQ A;  5HE2 A;  2H7D A;  4HAU B;  5JLJ B;  2D10 A;  3U8Z A;  2DYQ A;  2I5F A;  2OQB A;  3KSY A;  5JHH A;  5C5B B;  4HB3 B;  3QIJ A;  3LJU X;  1ZSQ A;  1W1H A;  4IOY X;  1X86 A;  2GCL A;  1W1D A;  1FGY A;  2RUK B;  1WGU A;  1MK7 B;  2H7E A;  5DIF B;  3AU4 A;  1IRS A;  1X1F A;  5DH9 B;  1V61 A;  2W2X D;  4YL8 A;  4Z2N A;  2CY4 A;  2J0K A;  2YS5 A;  4CHM A;  1FGZ A;  2KGX B;  4HB4 B;  3SUZ A;  1BTN A;  2D9Z A;  2P0F A;  2Z0P A;  1MIZ B;  1XOD A;  4BBK A;  2RGN B;  4DBB A;  2DFK A;  1GC6 A;  2KUP A;  4DX8 A;  2Z0Q A;  2I1K A;  1M7R A;  1MAI A;  1H10 A;  1FAO A;  5CLQ B;  2AEH A;  2EJ8 A;  3CIK A;  4TKN A;  5C79 A;  1SGH A;  3O96 A;  5DHF B;  5J3T A;  1TXD A;  1KZG A;  3CXB B;  4P7I A;  4MK0 A;  1NTY A;  3GYO A;  3SYX A;  4KHB B;  4DX9 0;  1Y5O A;  1UNR A;  3KRW A;  4ZRJ A;  4D0N B;  3SV1 A;  1UPQ A;  3FEH A;  4IFS A;  4KAX B;  1H4R A;  2W2X C;  3WYF B;  1OQN A;  1U5E A;  3BIN A;  2K00 A;  1UEF A;  1Y19 B;  1MIX A;  5D27 A;  3TVV A;  5FI0 A;  3F5R A;  1FB8 A;  3TCA A;  2HE7 A;  1V5M A;  4XWX A;  1PMS A;  3ODW A;  2GS0 A;  4EMO A;  4HAZ B;  4GPT B;  3ULC A;  1U29 A;  2L2I A;  2GJY A;  3GYP A;  2ROZ B;  4NY0 A;  3KRX A;  5HE0 A;  2QKL A;  2COF A;  5KQ1 A;  2Z0O A;  1P6S A;  2AL6 A;  2D9X A;  2EMS A;  5D3Y A;  2LUL A;  1FHX A;  1WG7 A;  2J59 M;  2CY5 A;  1UNP A;  1XKE A;  2Y8F A;  1DYN A;  1WGQ A;  1DDW A;  2UZR A;  5J3Q A;  5J3Y A;  4CYE A;  5D3X A;  3FSS A;  2YVC A;  3KZ1 A;  1K5D B;  2MKR A;  1I7A A;  1ZC3 B;  2D9Y A;  3QBV B;  4K2P A;  5DHA B;  4PNK A;  4HB0 B;  4GN1 A;  4TYZ A;  2R09 A;  2CRF A;  4A6F A;  1J19 A;  1W1G A;  1MK9 B;  1BTK A;  4ZRI A;  2LYD A;  2W2W A;  4K17 A;  3WA0 A;  4C0A A;  2G35 A;  1N3H A;  2J0J A;  2MDX A;  1SHC A;  3PVL A;  1MPH A;  1ZVR A;  2MFQ A;  2VRW B;  1DDM A;  2DKQ A;  2YT0 A;  4KHO A;  1LW3 A;  2DHI A;  2I1J A;  2J0M A;  2YS3 A;  3G9W A;  2RSG A;  2IYB A;  2K2U A;  3FM8 C;  2GCJ A;  1NU2 A;  1V89 A;  1XX0 A;  3D8F A;  1WJM A;  2CAY A;  2EC1 A;  4KVG B;  3A8Q A;  4HHV A;  3PSC A;  1WI1 A;  2N0Y A;  5D3W A;  3MDB C;  4K81 A;  4HB2 B;  2RVB B;  3PZD A;  1P5T A;  1U27 A;  2NMB A;  5JP4 A;  1XCG A; 
#chains in the Genus database with same CATH topology
 1B55 A;  1KZ7 A;  1ZC4 B;  2PZ1 A;  1U5G A;  2ADZ A;  1BWN A;  1RRP B;  2DYN A;  2I5C A;  2LKO A;  1EGX A;  4GOU A;  3TO1 A;  2UVM A;  4HAT B;  2MWN B;  3V5W A;  3B77 A;  1EVH A;  1OY2 A;  4WJ7 A;  4HDO A;  3T06 A;  4DXA B;  4HDQ A;  3PG7 A;  1WJ1 A;  1U2B A;  5FI1 A;  1OMW A;  1ISN A;  3HQC A;  2Z13 A;  3NWA A;  2P0D A;  3BJI A;  2COA A;  3ML4 A;  2Q13 A;  4QXA B;  2BCJ A;  4F7G A;  3OAN A;  2YSZ A;  4A6K A;  2VSZ A;  4GNK B;  1BAK A;  2EMT A;  3AU5 A;  2K2J A;  3DXE A;  3F0W A;  5C5B A;  2D9W A;  3IVF A;  2XQN M;  2N23 A;  5M4Y B;  2FJL A;  1DRO A;  5GOW B;  3U7D A;  1UNQ A;  2Z59 A;  2P8V A;  4HAX B;  2LG1 A;  2D4Q A;  3RCP A;  2QKM A;  3A98 B;  1RJ2 A;  2V76 A;  2IFS A;  1PFJ A;  2COC A;  3NSU A;  4NSW A;  3PP2 A;  1GG3 A;  1NTV A;  3SO6 A;  2KR0 A;  2Y7B A;  3HW2 B;  5DI9 B;  4GZU A;  3A58 A;  5HE3 A;  2DA0 A;  5C6R A;  4HAV B;  2KUQ A;  2YRY A;  1KI1 B;  1E5W A;  3M1I B;  2VKI A;  1ZM0 A;  5HE1 A;  2Z4D A;  4ZRK A;  4HAW B;  2RLO A;  5KQ4 A;  1WVH A;  2UZS A;  3D8E A;  2COD A;  2L1C A;  3N7C A;  1V88 A;  1NI2 A;  2YS1 A;  2DX5 A;  4HSI A;  1T77 A;  2RNR B;  2Z14 A;  4F7H A;  5L81 A;  3PVU A;  5C16 A;  3TFM A;  1V5P A;  3A8P A;  3VIA A;  5D3V A;  1M7E A;  2YF0 A;  2LOZ A;  4IAP A;  4HAY B;  2ZPY A;  4A6H A;  2ELB A;  4A5K A;  2DKP A;  3PVW A;  1EF1 A;  4F7U P;  5LON B;  3HK0 A;  3TW1 A;  2M38 A;  2ELA A;  1U5F A;  2NZ8 B;  3D8D A;  3P6A A;  4D6W A;  4YON A;  2DHK A;  1MI1 A;  3PEG A;  4WSF A;  1TQZ A;  1Q67 A;  4KHA A;  4L6E A;  3X23 A;  3ZVR A;  1U5D A;  1I2H A;  4EKU A;  4GMV A;  5KCV A;  1QC6 A;  3NWD A;  4B6H A;  1P3R A;  3ULB A;  2D2Q A;  2LOX A;  1X05 A;  1XD4 A;  2Y8G A;  5JHG A;  1FHO A;  2DN6 A;  1ZYI A;  2P0H A;  1AQC A;  1FOE A;  3QWM A;  1LB1 A;  3P7Z A;  2YT1 A;  1DBH A;  2D11 A;  3ODX A;  1PLS A;  2HTH B;  1QQG A;  5LOP B;  2ROV A;  2OTX A;  4CHJ A;  4K2O A;  3NWF A;  4MY6 A;  5LG4 B;  3AJ4 A;  2JP2 A;  5I2M A;  1EAZ A;  1X1G A;  5EFX A;  2DHJ A;  1TJ6 A;  1XR0 B;  3DXD A;  4Z2M B;  5CLL B;  4GXB A;  1Z87 A;  2KCJ A;  3ZDT A;  2DTC A;  1AWE A;  1K5G B;  3DCX A;  3SNH A;  1GC7 A;  3KY9 A;  3MPX A;  2E2X A;  1UPR A;  2D9V A;  1J0W A;  4EJN A;  3ODO A;  2X18 A;  4WVF B;  1MKE A;  3DXC A;  3HSA A;  2DLW A;  4PQ0 A;  1DDV A;  4A6F B;  2M14 A;  4GMX B;  3UZT A;  1X11 A;  4H8S A;  2R0D A;  4MT7 A;  1V5U A;  3NW8 A;  4Y94 A;  2DX1 A;  1FHW A;  3VOQ A;  5HE2 A;  4CSQ A;  2H7D A;  4HAU B;  5JLJ B;  2NBV A;  2D10 A;  3U8Z A;  2KIE A;  2DYQ A;  2I5F A;  2OQB A;  3KSY A;  5JHH A;  2YT2 A;  5C5B B;  4HB3 B;  3QIJ A;  3LJU X;  1ZSQ A;  1W1H A;  4IOY X;  1X86 A;  2GCL A;  2FJU B;  1W1D A;  1FGY A;  2RUK B;  1WGU A;  1MK7 B;  2H7E A;  5DIF B;  3AU4 A;  1IRS A;  1X1F A;  5DH9 B;  1V61 A;  2W2X D;  4YL8 A;  4Z2N A;  2CY4 A;  2J0K A;  2YS5 A;  4CHM A;  1FGZ A;  2KGX B;  4HB4 B;  3SUZ A;  1BTN A;  2D9Z A;  2P0F A;  2Z0P A;  5IRS A;  1MIZ B;  1XOD A;  4BBK A;  2RGN B;  4DBB A;  2DFK A;  1GC6 A;  2KUP A;  4DX8 A;  2Z0Q A;  2I1K A;  1M7R A;  1MAI A;  1H10 A;  4L1R A;  1FAO A;  5CLQ B;  2AEH A;  2EJ8 A;  3CIK A;  4TKN A;  5C79 A;  1SGH A;  3O96 A;  5DHF B;  5J3T A;  1TXD A;  1KZG A;  3CXB B;  4P7I A;  3U12 A;  4MK0 A;  3FVC A;  1NTY A;  3GYO A;  3SYX A;  4KHB B;  4DX9 0;  1Y5O A;  4QJ4 B;  1UNR A;  3KRW A;  4ZRJ A;  4D0N B;  3SV1 A;  5I2S A;  1UPQ A;  3FEH A;  4IFS A;  4KAX B;  1H4R A;  2W2X C;  3WYF B;  1OQN A;  1U5E A;  3BIN A;  2K00 A;  1UEF A;  4QJ3 B;  1Y19 B;  1MIX A;  5D27 A;  3TVV A;  5FI0 A;  3F5R A;  1FB8 A;  3TCA A;  2HE7 A;  1V5M A;  4XWX A;  1PMS A;  3ODW A;  2GS0 A;  4EMO A;  4HAZ B;  4GPT B;  3ULC A;  1U29 A;  2L2I A;  2GJY A;  3GYP A;  2ROZ B;  4NY0 A;  4QJ5 B;  3KRX A;  5HE0 A;  2QKL A;  2COF A;  4OT1 A;  5KQ1 A;  2Z0O A;  1P6S A;  2AL6 A;  2D9X A;  2EMS A;  5D3Y A;  2LUL A;  1FHX A;  1WG7 A;  2J59 M;  2CY5 A;  4KHB A;  1UNP A;  1XKE A;  2Y8F A;  1DYN A;  1WGQ A;  1DDW A;  2R2Y A;  2UZR A;  5J3Q A;  5J3Y A;  4CYE A;  5D3X A;  3FSS A;  2GUM A;  2YVC A;  3KZ1 A;  1K5D B;  2MKR A;  1I7A A;  1ZC3 B;  2D9Y A;  3QBV B;  4K2P A;  5DHA B;  4PNK A;  4HB0 B;  4GN1 A;  4TYZ A;  2K8E A;  2R09 A;  2CRF A;  4A6F A;  1J19 A;  1W1G A;  1MK9 B;  1BTK A;  2KIG A;  4ZRI A;  2LYD A;  2W2W A;  4K17 A;  3WA0 A;  3OHM B;  4C0A A;  4DIX A;  2G35 A;  1N3H A;  2J0J A;  2MDX A;  1SHC A;  3PVL A;  1MPH A;  1ZVR A;  2MFQ A;  2VRW B;  3HIE A;  1DDM A;  2DKQ A;  2YT0 A;  2K49 A;  4KHO A;  1LW3 A;  2DHI A;  2I1J A;  2J0M A;  2YS3 A;  3G9W A;  2RSG A;  2IYB A;  2K2U A;  3FM8 C;  2GCJ A;  1NU2 A;  1V89 A;  1XX0 A;  2ZKM X;  3D8F A;  1WJM A;  2CAY A;  2EC1 A;  4KVG B;  4OSN A;  3A8Q A;  4HHV A;  3PSC A;  1WI1 A;  2N0Y A;  5D3W A;  3MDB C;  4K81 A;  4HB2 B;  2RVB B;  3PZD A;  1P5T A;  2RRF A;  1U27 A;  2NMB A;  5JP4 A;  1XCG A; 
#chains in the Genus database with same CATH homology
 1B55 A;  1KZ7 A;  1ZC4 B;  2PZ1 A;  1U5G A;  2ADZ A;  1BWN A;  1RRP B;  2DYN A;  2I5C A;  2LKO A;  1EGX A;  3TO1 A;  2UVM A;  4HAT B;  2MWN B;  3V5W A;  1EVH A;  1OY2 A;  4WJ7 A;  4HDO A;  3T06 A;  4DXA B;  4HDQ A;  3PG7 A;  1WJ1 A;  1U2B A;  5FI1 A;  1OMW A;  1ISN A;  3HQC A;  2P0D A;  3BJI A;  2COA A;  3ML4 A;  2Q13 A;  2BCJ A;  4F7G A;  3OAN A;  2YSZ A;  4A6K A;  2VSZ A;  1BAK A;  2EMT A;  3AU5 A;  2K2J A;  3DXE A;  3F0W A;  5C5B A;  2D9W A;  3IVF A;  2XQN M;  2N23 A;  2FJL A;  1DRO A;  5GOW B;  3U7D A;  1UNQ A;  2P8V A;  4HAX B;  2LG1 A;  2D4Q A;  3RCP A;  2QKM A;  3A98 B;  1RJ2 A;  2V76 A;  2IFS A;  1PFJ A;  2COC A;  3NSU A;  4NSW A;  3PP2 A;  1GG3 A;  1NTV A;  3SO6 A;  2Y7B A;  3HW2 B;  5DI9 B;  4GZU A;  5HE3 A;  2DA0 A;  5C6R A;  4HAV B;  2YRY A;  1KI1 B;  1E5W A;  3M1I B;  2VKI A;  1ZM0 A;  5HE1 A;  4ZRK A;  4HAW B;  2RLO A;  5KQ4 A;  1WVH A;  2UZS A;  3D8E A;  2COD A;  2L1C A;  3N7C A;  1V88 A;  1NI2 A;  2YS1 A;  2DX5 A;  5L81 A;  2RNR B;  4F7H A;  3PVU A;  5C16 A;  3TFM A;  1V5P A;  3A8P A;  3VIA A;  5D3V A;  1M7E A;  2YF0 A;  2LOZ A;  4IAP A;  4HAY B;  2ZPY A;  4A6H A;  2ELB A;  4A5K A;  2DKP A;  3PVW A;  1EF1 A;  4F7U P;  5LON B;  3HK0 A;  3TW1 A;  2M38 A;  2ELA A;  1U5F A;  2NZ8 B;  3D8D A;  3P6A A;  4YON A;  2DHK A;  3PEG A;  4WSF A;  1TQZ A;  1Q67 A;  4KHA A;  4L6E A;  3X23 A;  3ZVR A;  1U5D A;  1I2H A;  4EKU A;  4GMV A;  5KCV A;  1QC6 A;  4B6H A;  1P3R A;  3ULB A;  2D2Q A;  2LOX A;  1X05 A;  1XD4 A;  2Y8G A;  5JHG A;  1FHO A;  2DN6 A;  2P0H A;  1AQC A;  3QWM A;  1FOE A;  1LB1 A;  3P7Z A;  2YT1 A;  1DBH A;  2D11 A;  3ODX A;  1PLS A;  2HTH B;  1QQG A;  5LOP B;  2ROV A;  2OTX A;  4CHJ A;  4K2O A;  4MY6 A;  3AJ4 A;  2JP2 A;  1EAZ A;  1X1G A;  5EFX A;  2DHJ A;  1TJ6 A;  1XR0 B;  3DXD A;  4Z2M B;  5CLL B;  4GXB A;  1Z87 A;  2KCJ A;  3ZDT A;  2DTC A;  1AWE A;  1K5G B;  3SNH A;  1GC7 A;  3KY9 A;  3MPX A;  2E2X A;  1UPR A;  2D9V A;  1J0W A;  4EJN A;  3ODO A;  2X18 A;  4WVF B;  1MKE A;  3DXC A;  2DLW A;  4PQ0 A;  1DDV A;  4A6F B;  2M14 A;  4GMX B;  3UZT A;  1X11 A;  4H8S A;  2R0D A;  4MT7 A;  1V5U A;  4Y94 A;  2DX1 A;  1FHW A;  3VOQ A;  5HE2 A;  2H7D A;  4HAU B;  5JLJ B;  2D10 A;  3U8Z A;  2DYQ A;  2I5F A;  2OQB A;  3KSY A;  5JHH A;  5C5B B;  4HB3 B;  3QIJ A;  3LJU X;  1ZSQ A;  1W1H A;  4IOY X;  1X86 A;  2GCL A;  1W1D A;  1FGY A;  2RUK B;  1WGU A;  1MK7 B;  2H7E A;  5DIF B;  3AU4 A;  1IRS A;  1X1F A;  5DH9 B;  1V61 A;  2W2X D;  4YL8 A;  4Z2N A;  2CY4 A;  2J0K A;  2YS5 A;  4CHM A;  1FGZ A;  2KGX B;  4HB4 B;  3SUZ A;  1BTN A;  2D9Z A;  2P0F A;  2Z0P A;  1MIZ B;  1XOD A;  4BBK A;  2RGN B;  4DBB A;  2DFK A;  1GC6 A;  2KUP A;  4DX8 A;  2Z0Q A;  2I1K A;  1M7R A;  1MAI A;  1H10 A;  1FAO A;  5CLQ B;  2AEH A;  2EJ8 A;  3CIK A;  4TKN A;  5C79 A;  1SGH A;  3O96 A;  5DHF B;  5J3T A;  1TXD A;  1KZG A;  3CXB B;  4P7I A;  4MK0 A;  1NTY A;  3GYO A;  3SYX A;  4KHB B;  4DX9 0;  1Y5O A;  1UNR A;  3KRW A;  4ZRJ A;  4D0N B;  3SV1 A;  1UPQ A;  3FEH A;  4IFS A;  4KAX B;  1H4R A;  2W2X C;  3WYF B;  1OQN A;  1U5E A;  3BIN A;  2K00 A;  1UEF A;  1Y19 B;  1MIX A;  5D27 A;  3TVV A;  5FI0 A;  3F5R A;  1FB8 A;  3TCA A;  2HE7 A;  1V5M A;  4XWX A;  1PMS A;  3ODW A;  2GS0 A;  4EMO A;  4HAZ B;  4GPT B;  3ULC A;  1U29 A;  2L2I A;  2GJY A;  3GYP A;  2ROZ B;  4NY0 A;  3KRX A;  5HE0 A;  2QKL A;  2COF A;  5KQ1 A;  2Z0O A;  1P6S A;  2AL6 A;  2D9X A;  2EMS A;  5D3Y A;  2LUL A;  1FHX A;  1WG7 A;  2J59 M;  2CY5 A;  1UNP A;  1XKE A;  2Y8F A;  1DYN A;  1WGQ A;  1DDW A;  2UZR A;  5J3Q A;  5J3Y A;  4CYE A;  5D3X A;  3FSS A;  2YVC A;  3KZ1 A;  1K5D B;  2MKR A;  1I7A A;  1ZC3 B;  2D9Y A;  3QBV B;  4K2P A;  5DHA B;  4PNK A;  4HB0 B;  4GN1 A;  4TYZ A;  2R09 A;  2CRF A;  4A6F A;  1J19 A;  1W1G A;  1MK9 B;  1BTK A;  4ZRI A;  2LYD A;  2W2W A;  4K17 A;  3WA0 A;  4C0A A;  2G35 A;  1N3H A;  2J0J A;  2MDX A;  1SHC A;  3PVL A;  1MPH A;  1ZVR A;  2MFQ A;  2VRW B;  1DDM A;  2DKQ A;  2YT0 A;  4KHO A;  1LW3 A;  2DHI A;  2I1J A;  2J0M A;  2YS3 A;  3G9W A;  2RSG A;  2IYB A;  2K2U A;  3FM8 C;  2GCJ A;  1NU2 A;  1V89 A;  1XX0 A;  3D8F A;  1WJM A;  2CAY A;  2EC1 A;  4KVG B;  3A8Q A;  4HHV A;  3PSC A;  1WI1 A;  2N0Y A;  5D3W A;  3MDB C;  4K81 A;  4HB2 B;  2RVB B;  3PZD A;  1P5T A;  1U27 A;  2NMB A;  5JP4 A;  1XCG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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