2UZRA

A transforming mutation in the pleckstrin homology domain of akt1 in cancer (akt1-ph_e17k)
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
118
structure length
113
Chain Sequence
DVAIVKEGWLHKRGKYIKTWRPRYFLLKNDGTFIGYKERPREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords RAC-alpha serine/threonine-protein kinase
publication title A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 30
structure length 113
sequence length 118
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-05-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 2uzrA00
2DA0A 4Z2NA 1UNPA 2D9YA 2COFA 4GZUA 5HE1A 1Y19B 1WI1A 3V5WA 2AL6A 1U27A 3U8ZA 1IRSA 1M7EA 2DYQA 4KAXB 2KGXB 2ADZA 3HK0A 1FHXA 3PZDA 2K00A 4K2PA 2NMBA 4HAYB 3RCPA 4WJ7A 1J19A 3PP2A 1MAIA 2EC1A 3PG7A 2D2QA 1X1GA 4EJNA 5D3VA 3KZ1A 3ULBA 2Z0OA 3P7ZA 4GXBA 4TYZA 4IAPA 3F5RA 4NY0A 2YF0A 2EMSA 2L1CA 1W1GA 4C0AA 2AEHA 1DDMA 4Z2MB 2V76A 1GC7A 2LULA 4KHOA 2VRWB 3TFMA 1TJ6A 2YT0A 4BBKA 2YT1A 5DHFB 2I1JA 3SYXA 1WGUA 1N3HA 5D3WA 1MK7B 1W1HA 1TQZA 4GPTB 3OANA 1BTNA 2BCJA 2GS0A 3N7CA 4IOYX 1WVHA 2DHJA 4F7UP 3SUZA 3ULCA 1WGQA 5LOPB 3QIJA 1XD4A 1UNQA 2Z0PA 3VIAA 1EAZA 1QC6A 3TO1A 3SO6A 2RVBB 2W2WA 3O96A 3UZTA 1V88A 2GCLA 4A6KA 4CHJA 2DKPA 1MIZB 2D11A 2K2JA 2MFQA 1X05A 4K81A 2KUPA 4HAUB 2D9ZA 4YL8A 1FGZA 2DHKA 3MPXA 2P0FA 4K17A 1MK9B 1X86A 2IYBA 2YRYA 4HATB 3FM8C 4A6HA 3ZVRA 4EKUA 3WA0A 3KRWA 1BAKA 1WG7A 3A98B 1SHCA 3T06A 2ZPYA 1H4RA 3CIKA 2IFSA 3FSSA 4HB4B 2MKRA 2HTHB 1U5DA 2D4QA 2RNRB 5FI0A 3G9WA 4IFSA 3SV1A 2GJYA 1OQNA 2M14A 1NTVA 1AWEA 1KI1B 1FOEA 2I1KA 1MIXA 4WSFA 3PVWA 1DBHA 2UZSA 2LOXA 4L6EA 4XWXA 3KSYA 3P6AA 2DYNA 4CHMA 4A6FB 5JHGA 1OMWA 2CY4A 1ZC3B 1XODA 3A8QA 2Y7BA 3QWMA 2CRFA 1DROA 5J3TA 1SGHA 4DX8A 1J0WA 2XQNM 1K5GB 1UNRA 2CY5A 1U29A 1W1DA 3DXCA 1NI2A 1P5TA 1Y5OA 3KY9A 1XX0A 1EVHA 1I7AA 3SNHA 1M7RA 5JP4A 1ZVRA 4HB2B 1U5FA 1NU2A 2YS3A 1KZGA 2H7DA 4HB0B 1OY2A 1MKEA 4ZRJA 2ROVA 1X1FA 2QKLA 1EGXA 5C79A 3LJUX 3WYFB 1LB1A 2D9XA 2VKIA 2J59M 3HW2B 3PVLA 5DHAB 4F7HA 1PLSA 1V61A 2N23A 1XR0B 4NSWA 5JLJB 3PEGA 2YS5A 4DXAB 1ZM0A 2P8VA 2W2XD 2G35A 1XCGA 3IVFA 2J0KA 4GN1A 4K2OA 3TW1A 1UPQA 1Q67A 2VSZA 1I2HA 2I5CA 4P7IA 2J0JA 2CAYA 3NSUA 1RJ2A 2COCA 1B55A 2Y8GA 1QQGA 1WJMA 5J3QA 4H8SA 2YVCA 5C6RA 5D27A 2OQBA 1V5MA 3GYPA 1UEFA 1Z87A 2D9VA 2RSGA 2GCJA 1X11A 3AU4A 3AU5A 5D3XA 2FJLA 2KCJA 2DX1A 4PNKA 5L81A 3BJIA 3AJ4A 1DYNA 4HAZB 2NZ8B 2JP2A 3PSCA 2MWNB 1P6SA 1E5WA 1P3RA 1DDVA 5KQ4A 1PMSA 2RGNB 5DIFB 4HDOA 2L2IA 2I5FA 2YSZA 5C16A 5FI1A 5D3YA 2N0YA 1V89A 2P0DA 2RLOA 5C5BA 5JHHA 2MDXA 3QBVB 2J0MA 5EFXA 2RUKB 3ODOA 1H10A 3ODWA 4HAVB 1U5GA 5HE2A 2COAA 2P0HA 1ZC4B 1BTKA 2ELAA 1V5UA 4A6FA 1KZ7A 5HE3A 1DDWA 5J3YA 4Y94A 1EF1A 1LW3A 2R0DA 3ZDTA 3D8FA 2DHIA 2LG1A 4GMXB 2Z0QA 2E2XA 2DKQA 4F7GA 2H7EA 2LOZA 5LONB 2PZ1A 2X18A 1GG3A 4ZRKA 4KHBB 4KVGB 4MK0A 2EJ8A 4DX90 3M1IB 4PQ0A 4TKNA 4D0NB 1AQCA 1TXDA 2DLWA 3U7DA 3F0WA 4GMVA 4B6HA 4CYEA 1K5DB 1ZSQA 2DFKA 2LKOA 1FHWA 1V5PA 2DX5A 5GOWB 1NTYA 3KRXA 2M38A 2EMTA 2UZRA 5KCVA 3FEHA 3D8DA 4DBBA 3PVUA 2W2XC 4MY6A 3X23A 1U5EA 2LYDA 4A5KA 3GYOA 3TVVA 4KHAA 5HE0A 4EMOA 4ZRIA 2R09A 2Q13A 1MPHA 4MT7A 4HHVA 3ML4A 3DXEA 1U2BA 4WVFB 1FHOA 1FAOA 2ROZB 4YONA 1FGYA 2QKMA 2D10A 3A8PA 2K2UA 3D8EA 3TCAA 4HAXB 4HB3B 1RRPB 1PFJA 2CODA 2UVMA 1ISNA 1BWNA 2YS1A 1UPRA 2HE7A 1XKEA 3MDBC 1GC6A 2DN6A 5DI9B 3HQCA 4HAWB 5CLQB 3VOQA 2OTXA 2ELBA 2Y8FA 1FB8A 3BINA 1WJ1A 3DXDA 5CLLB 5C5BB 2D9WA 4HDQA 2DTCA 3ODXA 5DH9B 5KQ1A 3CXBB
chains in the Genus database with same CATH superfamily
2DA0A 4Z2NA 1UNPA 2D9YA 2COFA 3HSAA 4GZUA 5HE1A 1Y19B 1WI1A 3V5WA 2R2YA 2AL6A 1U27A 3U8ZA 1IRSA 1M7EA 2DYQA 1ZYIA 4KAXB 2KGXB 2ADZA 3HK0A 1FHXA 3PZDA 2K00A 4K2PA 2NMBA 4HAYB 3RCPA 4WJ7A 2K49A 1J19A 3PP2A 1MAIA 2EC1A 3PG7A 2D2QA 1X1GA 4EJNA 5D3VA 3KZ1A 3ULBA 2Z0OA 3P7ZA 4GXBA 4TYZA 4IAPA 3F5RA 4NY0A 2YF0A 2EMSA 2L1CA 1W1GA 4C0AA 2AEHA 1MI1A 3OHMB 1DDMA 4Z2MB 2V76A 1GC7A 2LULA 4KHOA 2VRWB 3TFMA 1TJ6A 2YT0A 4BBKA 2YT1A 5DHFB 3A58A 2I1JA 3SYXA 2YT2A 1WGUA 1N3HA 5D3WA 1MK7B 1W1HA 1TQZA 4GPTB 5I2MA 3OANA 1BTNA 2BCJA 4QXAB 2GS0A 3N7CA 4IOYX 4QJ4B 1WVHA 2DHJA 4F7UP 3SUZA 3ULCA 1WGQA 5LOPB 3QIJA 1XD4A 1UNQA 2Z0PA 4GOUA 3VIAA 1EAZA 1QC6A 3TO1A 3SO6A 2RVBB 2W2WA 3O96A 3UZTA 1V88A 2GCLA 4A6KA 4CHJA 2DKPA 1MIZB 2D11A 2K2JA 2MFQA 1X05A 4K81A 2KUPA 4HAUB 2D9ZA 4YL8A 1FGZA 2DHKA 3MPXA 2P0FA 4K17A 1MK9B 1X86A 2IYBA 2YRYA 4HATB 3FM8C 4A6HA 4OSNA 3ZVRA 4EKUA 3WA0A 3KRWA 1BAKA 1WG7A 3A98B 1SHCA 3T06A 2ZPYA 1H4RA 3CIKA 2IFSA 3FSSA 4HB4B 2MKRA 4HSIA 2Z59A 2HTHB 1U5DA 2D4QA 3DCXA 2RNRB 2KR0A 2NBVA 5FI0A 3G9WA 4IFSA 3SV1A 2GJYA 1OQNA 2M14A 1NTVA 1AWEA 1KI1B 1FOEA 2I1KA 1MIXA 4WSFA 3PVWA 1DBHA 2UZSA 2LOXA 4L6EA 4XWXA 3KSYA 3P6AA 2DYNA 4CHMA 4A6FB 5LG4B 5JHGA 1OMWA 2CY4A 1ZC3B 1XODA 3NWDA 3A8QA 2Y7BA 3QWMA 2CRFA 1DROA 5J3TA 1SGHA 4DX8A 1J0WA 2XQNM 1K5GB 1UNRA 2CY5A 1U29A 1W1DA 3DXCA 1NI2A 1P5TA 1Y5OA 3KY9A 1XX0A 1EVHA 1I7AA 3SNHA 3FVCA 1M7RA 5JP4A 1ZVRA 4HB2B 1U5FA 1T77A 1NU2A 4QJ5B 2YS3A 1KZGA 2H7DA 4HB0B 1OY2A 1MKEA 4ZRJA 2ROVA 1X1FA 2Z4DA 2QKLA 1EGXA 5C79A 3LJUX 3WYFB 1LB1A 2KUQA 2D9XA 4KHBA 2VKIA 2J59M 3HW2B 3PVLA 4D6WA 3NWAA 5DHAB 4F7HA 1PLSA 1V61A 2N23A 1XR0B 4NSWA 5JLJB 3PEGA 2YS5A 4DXAB 1ZM0A 2P8VA 2W2XD 2G35A 1XCGA 3IVFA 2J0KA 4GN1A 4K2OA 3TW1A 1UPQA 1Q67A 2VSZA 1I2HA 2I5CA 4P7IA 2J0JA 2CAYA 3NSUA 1RJ2A 2COCA 1B55A 2Y8GA 1QQGA 1WJMA 5J3QA 4H8SA 2YVCA 5C6RA 5D27A 2OQBA 1V5MA 3B77A 3GYPA 1UEFA 2RRFA 1Z87A 2D9VA 2RSGA 5IRSA 2GCJA 1X11A 3AU4A 3AU5A 5D3XA 2FJLA 2KCJA 3NW8A 2DX1A 4PNKA 5L81A 3U12A 3BJIA 3AJ4A 1DYNA 4GNKB 4HAZB 2NZ8B 2JP2A 3PSCA 2MWNB 1P6SA 1E5WA 5I2SA 1P3RA 1DDVA 5KQ4A 1PMSA 2RGNB 5DIFB 4HDOA 3HIEA 2L2IA 4CSQA 2I5FA 2YSZA 5C16A 5FI1A 5D3YA 2N0YA 1V89A 2P0DA 2Z14A 2RLOA 5C5BA 2K8EA 5JHHA 2MDXA 3QBVB 2J0MA 5EFXA 2RUKB 3ODOA 1H10A 3ODWA 4HAVB 5M4YB 1U5GA 5HE2A 2COAA 2P0HA 1ZC4B 4DIXA 1BTKA 2ELAA 1V5UA 4A6FA 1KZ7A 5HE3A 1DDWA 5J3YA 4Y94A 1EF1A 1LW3A 2R0DA 3ZDTA 3D8FA 2DHIA 2LG1A 4GMXB 2Z0QA 2E2XA 2DKQA 4F7GA 2H7EA 2GUMA 2LOZA 5LONB 2PZ1A 2X18A 1GG3A 4ZRKA 4KHBB 4KVGB 4MK0A 2EJ8A 4DX90 2FJUB 3M1IB 4PQ0A 4TKNA 4D0NB 1AQCA 2KIGA 1TXDA 2DLWA 3U7DA 3F0WA 4GMVA 4B6HA 4CYEA 1K5DB 1ZSQA 3NWFA 2DFKA 2LKOA 1FHWA 1V5PA 2DX5A 2KIEA 5GOWB 1NTYA 3KRXA 2M38A 2EMTA 2UZRA 5KCVA 3FEHA 3D8DA 4DBBA 3PVUA 2W2XC 4MY6A 3X23A 1U5EA 2LYDA 4A5KA 3GYOA 3TVVA 4KHAA 5HE0A 2ZKMX 4EMOA 4ZRIA 2R09A 2Q13A 1MPHA 4MT7A 4HHVA 3ML4A 3DXEA 1U2BA 4WVFB 1FHOA 1FAOA 2ROZB 4YONA 1FGYA 2QKMA 2D10A 3A8PA 2K2UA 3D8EA 3TCAA 4HAXB 4HB3B 4OT1A 1RRPB 1PFJA 2CODA 2UVMA 1ISNA 1BWNA 2YS1A 1UPRA 4L1RA 2HE7A 1XKEA 3MDBC 1GC6A 2DN6A 5DI9B 3HQCA 4HAWB 5CLQB 3VOQA 2OTXA 2ELBA 4QJ3B 2Y8FA 1FB8A 3BINA 1WJ1A 3DXDA 5CLLB 2Z13A 5C5BB 2D9WA 4HDQA 2DTCA 3ODXA 5DH9B 5KQ1A 3CXBB
chains in the Genus database with same CATH topology
2DA0A 4Z2NA 1UNPA 2D9YA 2COFA 4GZUA 5HE1A 1Y19B 1WI1A 3V5WA 2AL6A 1U27A 3U8ZA 1IRSA 1M7EA 2DYQA 4KAXB 2KGXB 2ADZA 3HK0A 1FHXA 3PZDA 2K00A 4K2PA 2NMBA 4HAYB 3RCPA 4WJ7A 1J19A 3PP2A 1MAIA 2EC1A 3PG7A 2D2QA 1X1GA 4EJNA 5D3VA 3KZ1A 3ULBA 2Z0OA 3P7ZA 4GXBA 4TYZA 4IAPA 3F5RA 4NY0A 2YF0A 2EMSA 2L1CA 1W1GA 4C0AA 2AEHA 1DDMA 4Z2MB 2V76A 1GC7A 2LULA 4KHOA 2VRWB 3TFMA 1TJ6A 2YT0A 4BBKA 2YT1A 5DHFB 2I1JA 3SYXA 1WGUA 1N3HA 5D3WA 1MK7B 1W1HA 1TQZA 4GPTB 3OANA 1BTNA 2BCJA 2GS0A 3N7CA 4IOYX 1WVHA 2DHJA 4F7UP 3SUZA 3ULCA 1WGQA 5LOPB 3QIJA 1XD4A 1UNQA 2Z0PA 3VIAA 1EAZA 1QC6A 3TO1A 3SO6A 2RVBB 2W2WA 3O96A 3UZTA 1V88A 2GCLA 4A6KA 4CHJA 2DKPA 1MIZB 2D11A 2K2JA 2MFQA 1X05A 4K81A 2KUPA 4HAUB 2D9ZA 4YL8A 1FGZA 2DHKA 3MPXA 2P0FA 4K17A 1MK9B 1X86A 2IYBA 2YRYA 4HATB 3FM8C 4A6HA 3ZVRA 4EKUA 3WA0A 3KRWA 1BAKA 1WG7A 3A98B 1SHCA 3T06A 2ZPYA 1H4RA 3CIKA 2IFSA 3FSSA 4HB4B 2MKRA 2HTHB 1U5DA 2D4QA 2RNRB 5FI0A 3G9WA 4IFSA 3SV1A 2GJYA 1OQNA 2M14A 1NTVA 1AWEA 1KI1B 1FOEA 2I1KA 1MIXA 4WSFA 3PVWA 1DBHA 2UZSA 2LOXA 4L6EA 4XWXA 3KSYA 3P6AA 2DYNA 4CHMA 4A6FB 5JHGA 1OMWA 2CY4A 1ZC3B 1XODA 3A8QA 2Y7BA 3QWMA 2CRFA 1DROA 5J3TA 1SGHA 4DX8A 1J0WA 2XQNM 1K5GB 1UNRA 2CY5A 1U29A 1W1DA 3DXCA 1NI2A 1P5TA 1Y5OA 3KY9A 1XX0A 1EVHA 1I7AA 3SNHA 1M7RA 5JP4A 1ZVRA 4HB2B 1U5FA 1NU2A 2YS3A 1KZGA 2H7DA 4HB0B 1OY2A 1MKEA 4ZRJA 2ROVA 1X1FA 2QKLA 1EGXA 5C79A 3LJUX 3WYFB 1LB1A 2D9XA 2VKIA 2J59M 3HW2B 3PVLA 5DHAB 4F7HA 1PLSA 1V61A 2N23A 1XR0B 4NSWA 5JLJB 3PEGA 2YS5A 4DXAB 1ZM0A 2P8VA 2W2XD 2G35A 1XCGA 3IVFA 2J0KA 4GN1A 4K2OA 3TW1A 1UPQA 1Q67A 2VSZA 1I2HA 2I5CA 4P7IA 2J0JA 2CAYA 3NSUA 1RJ2A 2COCA 1B55A 2Y8GA 1QQGA 1WJMA 5J3QA 4H8SA 2YVCA 5C6RA 5D27A 2OQBA 1V5MA 3GYPA 1UEFA 1Z87A 2D9VA 2RSGA 2GCJA 1X11A 3AU4A 3AU5A 5D3XA 2FJLA 2KCJA 2DX1A 4PNKA 5L81A 3BJIA 3AJ4A 1DYNA 4HAZB 2NZ8B 2JP2A 3PSCA 2MWNB 1P6SA 1E5WA 1P3RA 1DDVA 5KQ4A 1PMSA 2RGNB 5DIFB 4HDOA 2L2IA 2I5FA 2YSZA 5C16A 5FI1A 5D3YA 2N0YA 1V89A 2P0DA 2RLOA 5C5BA 5JHHA 2MDXA 3QBVB 2J0MA 5EFXA 2RUKB 3ODOA 1H10A 3ODWA 4HAVB 1U5GA 5HE2A 2COAA 2P0HA 1ZC4B 1BTKA 2ELAA 1V5UA 4A6FA 1KZ7A 5HE3A 1DDWA 5J3YA 4Y94A 1EF1A 1LW3A 2R0DA 3ZDTA 3D8FA 2DHIA 2LG1A 4GMXB 2Z0QA 2E2XA 2DKQA 4F7GA 2H7EA 2LOZA 5LONB 2PZ1A 2X18A 1GG3A 4ZRKA 4KHBB 4KVGB 4MK0A 2EJ8A 4DX90 3M1IB 4PQ0A 4TKNA 4D0NB 1AQCA 1TXDA 2DLWA 3U7DA 3F0WA 4GMVA 4B6HA 4CYEA 1K5DB 1ZSQA 2DFKA 2LKOA 1FHWA 1V5PA 2DX5A 5GOWB 1NTYA 3KRXA 2M38A 2EMTA 2UZRA 5KCVA 3FEHA 3D8DA 4DBBA 3PVUA 2W2XC 4MY6A 3X23A 1U5EA 2LYDA 4A5KA 3GYOA 3TVVA 4KHAA 5HE0A 4EMOA 4ZRIA 2R09A 2Q13A 1MPHA 4MT7A 4HHVA 3ML4A 3DXEA 1U2BA 4WVFB 1FHOA 1FAOA 2ROZB 4YONA 1FGYA 2QKMA 2D10A 3A8PA 2K2UA 3D8EA 3TCAA 4HAXB 4HB3B 1RRPB 1PFJA 2CODA 2UVMA 1ISNA 1BWNA 2YS1A 1UPRA 2HE7A 1XKEA 3MDBC 1GC6A 2DN6A 5DI9B 3HQCA 4HAWB 5CLQB 3VOQA 2OTXA 2ELBA 2Y8FA 1FB8A 3BINA 1WJ1A 3DXDA 5CLLB 5C5BB 2D9WA 4HDQA 2DTCA 3ODXA 5DH9B 5KQ1A 3CXBB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DA0 A;  4Z2N A;  1UNP A;  2D9Y A;  2COF A;  4GZU A;  5HE1 A;  1Y19 B;  1WI1 A;  3V5W A;  2AL6 A;  1U27 A;  3U8Z A;  1IRS A;  1M7E A;  2DYQ A;  4KAX B;  2KGX B;  2ADZ A;  3HK0 A;  1FHX A;  3PZD A;  2K00 A;  4K2P A;  2NMB A;  4HAY B;  3RCP A;  4WJ7 A;  1J19 A;  3PP2 A;  1MAI A;  2EC1 A;  3PG7 A;  2D2Q A;  1X1G A;  4EJN A;  5D3V A;  3KZ1 A;  3ULB A;  2Z0O A;  3P7Z A;  4GXB A;  4TYZ A;  4IAP A;  3F5R A;  4NY0 A;  2YF0 A;  2EMS A;  2L1C A;  1W1G A;  4C0A A;  2AEH A;  1DDM A;  4Z2M B;  2V76 A;  1GC7 A;  2LUL A;  4KHO A;  2VRW B;  3TFM A;  1TJ6 A;  2YT0 A;  4BBK A;  2YT1 A;  5DHF B;  2I1J A;  3SYX A;  1WGU A;  1N3H A;  5D3W A;  1MK7 B;  1W1H A;  1TQZ A;  4GPT B;  3OAN A;  1BTN A;  2BCJ A;  2GS0 A;  3N7C A;  4IOY X;  1WVH A;  2DHJ A;  4F7U P;  3SUZ A;  3ULC A;  1WGQ A;  5LOP B;  3QIJ A;  1XD4 A;  1UNQ A;  2Z0P A;  3VIA A;  1EAZ A;  1QC6 A;  3TO1 A;  3SO6 A;  2RVB B;  2W2W A;  3O96 A;  3UZT A;  1V88 A;  2GCL A;  4A6K A;  4CHJ A;  2DKP A;  1MIZ B;  2D11 A;  2K2J A;  2MFQ A;  1X05 A;  4K81 A;  2KUP A;  4HAU B;  2D9Z A;  4YL8 A;  1FGZ A;  2DHK A;  3MPX A;  2P0F A;  4K17 A;  1MK9 B;  1X86 A;  2IYB A;  2YRY A;  4HAT B;  3FM8 C;  4A6H A;  3ZVR A;  4EKU A;  3WA0 A;  3KRW A;  1BAK A;  1WG7 A;  3A98 B;  1SHC A;  3T06 A;  2ZPY A;  1H4R A;  3CIK A;  2IFS A;  3FSS A;  4HB4 B;  2MKR A;  2HTH B;  1U5D A;  2D4Q A;  2RNR B;  5FI0 A;  3G9W A;  4IFS A;  3SV1 A;  2GJY A;  1OQN A;  2M14 A;  1NTV A;  1AWE A;  1KI1 B;  1FOE A;  2I1K A;  1MIX A;  4WSF A;  3PVW A;  1DBH A;  2UZS A;  2LOX A;  4L6E A;  4XWX A;  3KSY A;  3P6A A;  2DYN A;  4CHM A;  4A6F B;  5JHG A;  1OMW A;  2CY4 A;  1ZC3 B;  1XOD A;  3A8Q A;  2Y7B A;  3QWM A;  2CRF A;  1DRO A;  5J3T A;  1SGH A;  4DX8 A;  1J0W A;  2XQN M;  1K5G B;  1UNR A;  2CY5 A;  1U29 A;  1W1D A;  3DXC A;  1NI2 A;  1P5T A;  1Y5O A;  3KY9 A;  1XX0 A;  1EVH A;  1I7A A;  3SNH A;  1M7R A;  5JP4 A;  1ZVR A;  4HB2 B;  1U5F A;  1NU2 A;  2YS3 A;  1KZG A;  2H7D A;  4HB0 B;  1OY2 A;  1MKE A;  4ZRJ A;  2ROV A;  1X1F A;  2QKL A;  1EGX A;  5C79 A;  3LJU X;  3WYF B;  1LB1 A;  2D9X A;  2VKI A;  2J59 M;  3HW2 B;  3PVL A;  5DHA B;  4F7H A;  1PLS A;  1V61 A;  2N23 A;  1XR0 B;  4NSW A;  5JLJ B;  3PEG A;  2YS5 A;  4DXA B;  1ZM0 A;  2P8V A;  2W2X D;  2G35 A;  1XCG A;  3IVF A;  2J0K A;  4GN1 A;  4K2O A;  3TW1 A;  1UPQ A;  1Q67 A;  2VSZ A;  1I2H A;  2I5C A;  4P7I A;  2J0J A;  2CAY A;  3NSU A;  1RJ2 A;  2COC A;  1B55 A;  2Y8G A;  1QQG A;  1WJM A;  5J3Q A;  4H8S A;  2YVC A;  5C6R A;  5D27 A;  2OQB A;  1V5M A;  3GYP A;  1UEF A;  1Z87 A;  2D9V A;  2RSG A;  2GCJ A;  1X11 A;  3AU4 A;  3AU5 A;  5D3X A;  2FJL A;  2KCJ A;  2DX1 A;  4PNK A;  5L81 A;  3BJI A;  3AJ4 A;  1DYN A;  4HAZ B;  2NZ8 B;  2JP2 A;  3PSC A;  2MWN B;  1P6S A;  1E5W A;  1P3R A;  1DDV A;  5KQ4 A;  1PMS A;  2RGN B;  5DIF B;  4HDO A;  2L2I A;  2I5F A;  2YSZ A;  5C16 A;  5FI1 A;  5D3Y A;  2N0Y A;  1V89 A;  2P0D A;  2RLO A;  5C5B A;  5JHH A;  2MDX A;  3QBV B;  2J0M A;  5EFX A;  2RUK B;  3ODO A;  1H10 A;  3ODW A;  4HAV B;  1U5G A;  5HE2 A;  2COA A;  2P0H A;  1ZC4 B;  1BTK A;  2ELA A;  1V5U A;  4A6F A;  1KZ7 A;  5HE3 A;  1DDW A;  5J3Y A;  4Y94 A;  1EF1 A;  1LW3 A;  2R0D A;  3ZDT A;  3D8F A;  2DHI A;  2LG1 A;  4GMX B;  2Z0Q A;  2E2X A;  2DKQ A;  4F7G A;  2H7E A;  2LOZ A;  5LON B;  2PZ1 A;  2X18 A;  1GG3 A;  4ZRK A;  4KHB B;  4KVG B;  4MK0 A;  2EJ8 A;  4DX9 0;  3M1I B;  4PQ0 A;  4TKN A;  4D0N B;  1AQC A;  1TXD A;  2DLW A;  3U7D A;  3F0W A;  4GMV A;  4B6H A;  4CYE A;  1K5D B;  1ZSQ A;  2DFK A;  2LKO A;  1FHW A;  1V5P A;  2DX5 A;  5GOW B;  1NTY A;  3KRX A;  2M38 A;  2EMT A;  2UZR A;  5KCV A;  3FEH A;  3D8D A;  4DBB A;  3PVU A;  2W2X C;  4MY6 A;  3X23 A;  1U5E A;  2LYD A;  4A5K A;  3GYO A;  3TVV A;  4KHA A;  5HE0 A;  4EMO A;  4ZRI A;  2R09 A;  2Q13 A;  1MPH A;  4MT7 A;  4HHV A;  3ML4 A;  3DXE A;  1U2B A;  4WVF B;  1FHO A;  1FAO A;  2ROZ B;  4YON A;  1FGY A;  2QKM A;  2D10 A;  3A8P A;  2K2U A;  3D8E A;  3TCA A;  4HAX B;  4HB3 B;  1RRP B;  1PFJ A;  2COD A;  2UVM A;  1ISN A;  1BWN A;  2YS1 A;  1UPR A;  2HE7 A;  1XKE A;  3MDB C;  1GC6 A;  2DN6 A;  5DI9 B;  3HQC A;  4HAW B;  5CLQ B;  3VOQ A;  2OTX A;  2ELB A;  2Y8F A;  1FB8 A;  3BIN A;  1WJ1 A;  3DXD A;  5CLL B;  5C5B B;  2D9W A;  4HDQ A;  2DTC A;  3ODX A;  5DH9 B;  5KQ1 A;  3CXB B; 
#chains in the Genus database with same CATH topology
 2DA0 A;  4Z2N A;  1UNP A;  2D9Y A;  2COF A;  3HSA A;  4GZU A;  5HE1 A;  1Y19 B;  1WI1 A;  3V5W A;  2R2Y A;  2AL6 A;  1U27 A;  3U8Z A;  1IRS A;  1M7E A;  2DYQ A;  1ZYI A;  4KAX B;  2KGX B;  2ADZ A;  3HK0 A;  1FHX A;  3PZD A;  2K00 A;  4K2P A;  2NMB A;  4HAY B;  3RCP A;  4WJ7 A;  2K49 A;  1J19 A;  3PP2 A;  1MAI A;  2EC1 A;  3PG7 A;  2D2Q A;  1X1G A;  4EJN A;  5D3V A;  3KZ1 A;  3ULB A;  2Z0O A;  3P7Z A;  4GXB A;  4TYZ A;  4IAP A;  3F5R A;  4NY0 A;  2YF0 A;  2EMS A;  2L1C A;  1W1G A;  4C0A A;  2AEH A;  1MI1 A;  3OHM B;  1DDM A;  4Z2M B;  2V76 A;  1GC7 A;  2LUL A;  4KHO A;  2VRW B;  3TFM A;  1TJ6 A;  2YT0 A;  4BBK A;  2YT1 A;  5DHF B;  3A58 A;  2I1J A;  3SYX A;  2YT2 A;  1WGU A;  1N3H A;  5D3W A;  1MK7 B;  1W1H A;  1TQZ A;  4GPT B;  5I2M A;  3OAN A;  1BTN A;  2BCJ A;  4QXA B;  2GS0 A;  3N7C A;  4IOY X;  4QJ4 B;  1WVH A;  2DHJ A;  4F7U P;  3SUZ A;  3ULC A;  1WGQ A;  5LOP B;  3QIJ A;  1XD4 A;  1UNQ A;  2Z0P A;  4GOU A;  3VIA A;  1EAZ A;  1QC6 A;  3TO1 A;  3SO6 A;  2RVB B;  2W2W A;  3O96 A;  3UZT A;  1V88 A;  2GCL A;  4A6K A;  4CHJ A;  2DKP A;  1MIZ B;  2D11 A;  2K2J A;  2MFQ A;  1X05 A;  4K81 A;  2KUP A;  4HAU B;  2D9Z A;  4YL8 A;  1FGZ A;  2DHK A;  3MPX A;  2P0F A;  4K17 A;  1MK9 B;  1X86 A;  2IYB A;  2YRY A;  4HAT B;  3FM8 C;  4A6H A;  4OSN A;  3ZVR A;  4EKU A;  3WA0 A;  3KRW A;  1BAK A;  1WG7 A;  3A98 B;  1SHC A;  3T06 A;  2ZPY A;  1H4R A;  3CIK A;  2IFS A;  3FSS A;  4HB4 B;  2MKR A;  4HSI A;  2Z59 A;  2HTH B;  1U5D A;  2D4Q A;  3DCX A;  2RNR B;  2KR0 A;  2NBV A;  5FI0 A;  3G9W A;  4IFS A;  3SV1 A;  2GJY A;  1OQN A;  2M14 A;  1NTV A;  1AWE A;  1KI1 B;  1FOE A;  2I1K A;  1MIX A;  4WSF A;  3PVW A;  1DBH A;  2UZS A;  2LOX A;  4L6E A;  4XWX A;  3KSY A;  3P6A A;  2DYN A;  4CHM A;  4A6F B;  5LG4 B;  5JHG A;  1OMW A;  2CY4 A;  1ZC3 B;  1XOD A;  3NWD A;  3A8Q A;  2Y7B A;  3QWM A;  2CRF A;  1DRO A;  5J3T A;  1SGH A;  4DX8 A;  1J0W A;  2XQN M;  1K5G B;  1UNR A;  2CY5 A;  1U29 A;  1W1D A;  3DXC A;  1NI2 A;  1P5T A;  1Y5O A;  3KY9 A;  1XX0 A;  1EVH A;  1I7A A;  3SNH A;  3FVC A;  1M7R A;  5JP4 A;  1ZVR A;  4HB2 B;  1U5F A;  1T77 A;  1NU2 A;  4QJ5 B;  2YS3 A;  1KZG A;  2H7D A;  4HB0 B;  1OY2 A;  1MKE A;  4ZRJ A;  2ROV A;  1X1F A;  2Z4D A;  2QKL A;  1EGX A;  5C79 A;  3LJU X;  3WYF B;  1LB1 A;  2KUQ A;  2D9X A;  4KHB A;  2VKI A;  2J59 M;  3HW2 B;  3PVL A;  4D6W A;  3NWA A;  5DHA B;  4F7H A;  1PLS A;  1V61 A;  2N23 A;  1XR0 B;  4NSW A;  5JLJ B;  3PEG A;  2YS5 A;  4DXA B;  1ZM0 A;  2P8V A;  2W2X D;  2G35 A;  1XCG A;  3IVF A;  2J0K A;  4GN1 A;  4K2O A;  3TW1 A;  1UPQ A;  1Q67 A;  2VSZ A;  1I2H A;  2I5C A;  4P7I A;  2J0J A;  2CAY A;  3NSU A;  1RJ2 A;  2COC A;  1B55 A;  2Y8G A;  1QQG A;  1WJM A;  5J3Q A;  4H8S A;  2YVC A;  5C6R A;  5D27 A;  2OQB A;  1V5M A;  3B77 A;  3GYP A;  1UEF A;  2RRF A;  1Z87 A;  2D9V A;  2RSG A;  5IRS A;  2GCJ A;  1X11 A;  3AU4 A;  3AU5 A;  5D3X A;  2FJL A;  2KCJ A;  3NW8 A;  2DX1 A;  4PNK A;  5L81 A;  3U12 A;  3BJI A;  3AJ4 A;  1DYN A;  4GNK B;  4HAZ B;  2NZ8 B;  2JP2 A;  3PSC A;  2MWN B;  1P6S A;  1E5W A;  5I2S A;  1P3R A;  1DDV A;  5KQ4 A;  1PMS A;  2RGN B;  5DIF B;  4HDO A;  3HIE A;  2L2I A;  4CSQ A;  2I5F A;  2YSZ A;  5C16 A;  5FI1 A;  5D3Y A;  2N0Y A;  1V89 A;  2P0D A;  2Z14 A;  2RLO A;  5C5B A;  2K8E A;  5JHH A;  2MDX A;  3QBV B;  2J0M A;  5EFX A;  2RUK B;  3ODO A;  1H10 A;  3ODW A;  4HAV B;  5M4Y B;  1U5G A;  5HE2 A;  2COA A;  2P0H A;  1ZC4 B;  4DIX A;  1BTK A;  2ELA A;  1V5U A;  4A6F A;  1KZ7 A;  5HE3 A;  1DDW A;  5J3Y A;  4Y94 A;  1EF1 A;  1LW3 A;  2R0D A;  3ZDT A;  3D8F A;  2DHI A;  2LG1 A;  4GMX B;  2Z0Q A;  2E2X A;  2DKQ A;  4F7G A;  2H7E A;  2GUM A;  2LOZ A;  5LON B;  2PZ1 A;  2X18 A;  1GG3 A;  4ZRK A;  4KHB B;  4KVG B;  4MK0 A;  2EJ8 A;  4DX9 0;  2FJU B;  3M1I B;  4PQ0 A;  4TKN A;  4D0N B;  1AQC A;  2KIG A;  1TXD A;  2DLW A;  3U7D A;  3F0W A;  4GMV A;  4B6H A;  4CYE A;  1K5D B;  1ZSQ A;  3NWF A;  2DFK A;  2LKO A;  1FHW A;  1V5P A;  2DX5 A;  2KIE A;  5GOW B;  1NTY A;  3KRX A;  2M38 A;  2EMT A;  2UZR A;  5KCV A;  3FEH A;  3D8D A;  4DBB A;  3PVU A;  2W2X C;  4MY6 A;  3X23 A;  1U5E A;  2LYD A;  4A5K A;  3GYO A;  3TVV A;  4KHA A;  5HE0 A;  2ZKM X;  4EMO A;  4ZRI A;  2R09 A;  2Q13 A;  1MPH A;  4MT7 A;  4HHV A;  3ML4 A;  3DXE A;  1U2B A;  4WVF B;  1FHO A;  1FAO A;  2ROZ B;  4YON A;  1FGY A;  2QKM A;  2D10 A;  3A8P A;  2K2U A;  3D8E A;  3TCA A;  4HAX B;  4HB3 B;  4OT1 A;  1RRP B;  1PFJ A;  2COD A;  2UVM A;  1ISN A;  1BWN A;  2YS1 A;  1UPR A;  4L1R A;  2HE7 A;  1XKE A;  3MDB C;  1GC6 A;  2DN6 A;  5DI9 B;  3HQC A;  4HAW B;  5CLQ B;  3VOQ A;  2OTX A;  2ELB A;  4QJ3 B;  2Y8F A;  1FB8 A;  3BIN A;  1WJ1 A;  3DXD A;  5CLL B;  2Z13 A;  5C5B B;  2D9W A;  4HDQ A;  2DTC A;  3ODX A;  5DH9 B;  5KQ1 A;  3CXB B; 
#chains in the Genus database with same CATH homology
 2DA0 A;  4Z2N A;  1UNP A;  2D9Y A;  2COF A;  4GZU A;  5HE1 A;  1Y19 B;  1WI1 A;  3V5W A;  2AL6 A;  1U27 A;  3U8Z A;  1IRS A;  1M7E A;  2DYQ A;  4KAX B;  2KGX B;  2ADZ A;  3HK0 A;  1FHX A;  3PZD A;  2K00 A;  4K2P A;  2NMB A;  4HAY B;  3RCP A;  4WJ7 A;  1J19 A;  3PP2 A;  1MAI A;  2EC1 A;  3PG7 A;  2D2Q A;  1X1G A;  4EJN A;  5D3V A;  3KZ1 A;  3ULB A;  2Z0O A;  3P7Z A;  4GXB A;  4TYZ A;  4IAP A;  3F5R A;  4NY0 A;  2YF0 A;  2EMS A;  2L1C A;  1W1G A;  4C0A A;  2AEH A;  1DDM A;  4Z2M B;  2V76 A;  1GC7 A;  2LUL A;  4KHO A;  2VRW B;  3TFM A;  1TJ6 A;  2YT0 A;  4BBK A;  2YT1 A;  5DHF B;  2I1J A;  3SYX A;  1WGU A;  1N3H A;  5D3W A;  1MK7 B;  1W1H A;  1TQZ A;  4GPT B;  3OAN A;  1BTN A;  2BCJ A;  2GS0 A;  3N7C A;  4IOY X;  1WVH A;  2DHJ A;  4F7U P;  3SUZ A;  3ULC A;  1WGQ A;  5LOP B;  3QIJ A;  1XD4 A;  1UNQ A;  2Z0P A;  3VIA A;  1EAZ A;  1QC6 A;  3TO1 A;  3SO6 A;  2RVB B;  2W2W A;  3O96 A;  3UZT A;  1V88 A;  2GCL A;  4A6K A;  4CHJ A;  2DKP A;  1MIZ B;  2D11 A;  2K2J A;  2MFQ A;  1X05 A;  4K81 A;  2KUP A;  4HAU B;  2D9Z A;  4YL8 A;  1FGZ A;  2DHK A;  3MPX A;  2P0F A;  4K17 A;  1MK9 B;  1X86 A;  2IYB A;  2YRY A;  4HAT B;  3FM8 C;  4A6H A;  3ZVR A;  4EKU A;  3WA0 A;  3KRW A;  1BAK A;  1WG7 A;  3A98 B;  1SHC A;  3T06 A;  2ZPY A;  1H4R A;  3CIK A;  2IFS A;  3FSS A;  4HB4 B;  2MKR A;  2HTH B;  1U5D A;  2D4Q A;  2RNR B;  5FI0 A;  3G9W A;  4IFS A;  3SV1 A;  2GJY A;  1OQN A;  2M14 A;  1NTV A;  1AWE A;  1KI1 B;  1FOE A;  2I1K A;  1MIX A;  4WSF A;  3PVW A;  1DBH A;  2UZS A;  2LOX A;  4L6E A;  4XWX A;  3KSY A;  3P6A A;  2DYN A;  4CHM A;  4A6F B;  5JHG A;  1OMW A;  2CY4 A;  1ZC3 B;  1XOD A;  3A8Q A;  2Y7B A;  3QWM A;  2CRF A;  1DRO A;  5J3T A;  1SGH A;  4DX8 A;  1J0W A;  2XQN M;  1K5G B;  1UNR A;  2CY5 A;  1U29 A;  1W1D A;  3DXC A;  1NI2 A;  1P5T A;  1Y5O A;  3KY9 A;  1XX0 A;  1EVH A;  1I7A A;  3SNH A;  1M7R A;  5JP4 A;  1ZVR A;  4HB2 B;  1U5F A;  1NU2 A;  2YS3 A;  1KZG A;  2H7D A;  4HB0 B;  1OY2 A;  1MKE A;  4ZRJ A;  2ROV A;  1X1F A;  2QKL A;  1EGX A;  5C79 A;  3LJU X;  3WYF B;  1LB1 A;  2D9X A;  2VKI A;  2J59 M;  3HW2 B;  3PVL A;  5DHA B;  4F7H A;  1PLS A;  1V61 A;  2N23 A;  1XR0 B;  4NSW A;  5JLJ B;  3PEG A;  2YS5 A;  4DXA B;  1ZM0 A;  2P8V A;  2W2X D;  2G35 A;  1XCG A;  3IVF A;  2J0K A;  4GN1 A;  4K2O A;  3TW1 A;  1UPQ A;  1Q67 A;  2VSZ A;  1I2H A;  2I5C A;  4P7I A;  2J0J A;  2CAY A;  3NSU A;  1RJ2 A;  2COC A;  1B55 A;  2Y8G A;  1QQG A;  1WJM A;  5J3Q A;  4H8S A;  2YVC A;  5C6R A;  5D27 A;  2OQB A;  1V5M A;  3GYP A;  1UEF A;  1Z87 A;  2D9V A;  2RSG A;  2GCJ A;  1X11 A;  3AU4 A;  3AU5 A;  5D3X A;  2FJL A;  2KCJ A;  2DX1 A;  4PNK A;  5L81 A;  3BJI A;  3AJ4 A;  1DYN A;  4HAZ B;  2NZ8 B;  2JP2 A;  3PSC A;  2MWN B;  1P6S A;  1E5W A;  1P3R A;  1DDV A;  5KQ4 A;  1PMS A;  2RGN B;  5DIF B;  4HDO A;  2L2I A;  2I5F A;  2YSZ A;  5C16 A;  5FI1 A;  5D3Y A;  2N0Y A;  1V89 A;  2P0D A;  2RLO A;  5C5B A;  5JHH A;  2MDX A;  3QBV B;  2J0M A;  5EFX A;  2RUK B;  3ODO A;  1H10 A;  3ODW A;  4HAV B;  1U5G A;  5HE2 A;  2COA A;  2P0H A;  1ZC4 B;  1BTK A;  2ELA A;  1V5U A;  4A6F A;  1KZ7 A;  5HE3 A;  1DDW A;  5J3Y A;  4Y94 A;  1EF1 A;  1LW3 A;  2R0D A;  3ZDT A;  3D8F A;  2DHI A;  2LG1 A;  4GMX B;  2Z0Q A;  2E2X A;  2DKQ A;  4F7G A;  2H7E A;  2LOZ A;  5LON B;  2PZ1 A;  2X18 A;  1GG3 A;  4ZRK A;  4KHB B;  4KVG B;  4MK0 A;  2EJ8 A;  4DX9 0;  3M1I B;  4PQ0 A;  4TKN A;  4D0N B;  1AQC A;  1TXD A;  2DLW A;  3U7D A;  3F0W A;  4GMV A;  4B6H A;  4CYE A;  1K5D B;  1ZSQ A;  2DFK A;  2LKO A;  1FHW A;  1V5P A;  2DX5 A;  5GOW B;  1NTY A;  3KRX A;  2M38 A;  2EMT A;  2UZR A;  5KCV A;  3FEH A;  3D8D A;  4DBB A;  3PVU A;  2W2X C;  4MY6 A;  3X23 A;  1U5E A;  2LYD A;  4A5K A;  3GYO A;  3TVV A;  4KHA A;  5HE0 A;  4EMO A;  4ZRI A;  2R09 A;  2Q13 A;  1MPH A;  4MT7 A;  4HHV A;  3ML4 A;  3DXE A;  1U2B A;  4WVF B;  1FHO A;  1FAO A;  2ROZ B;  4YON A;  1FGY A;  2QKM A;  2D10 A;  3A8P A;  2K2U A;  3D8E A;  3TCA A;  4HAX B;  4HB3 B;  1RRP B;  1PFJ A;  2COD A;  2UVM A;  1ISN A;  1BWN A;  2YS1 A;  1UPR A;  2HE7 A;  1XKE A;  3MDB C;  1GC6 A;  2DN6 A;  5DI9 B;  3HQC A;  4HAW B;  5CLQ B;  3VOQ A;  2OTX A;  2ELB A;  2Y8F A;  1FB8 A;  3BIN A;  1WJ1 A;  3DXD A;  5CLL B;  5C5B B;  2D9W A;  4HDQ A;  2DTC A;  3ODX A;  5DH9 B;  5KQ1 A;  3CXB B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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