2UZRA

A transforming mutation in the pleckstrin homology domain of akt1 in cancer (akt1-ph_e17k)
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
118
structure length
113
Chain Sequence
DVAIVKEGWLHKRGKYIKTWRPRYFLLKNDGTFIGYKERPREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords RAC-alpha serine/threonine-protein kinase
publication title A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
pubmed doi rcsb
source organism Homo sapiens
total genus 30
structure length 113
sequence length 118
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-05-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 2uzrA00
2DTCA 1BWNA 2ADZA 2L1CA 1FHWA 3LJUX 2BCJA 5LOPB 1LB1A 1FGZA 3U7DA 2CAYA 2G35A 3HK0A 1LW3A 1DROA 5KQ1A 1MIZB 1AWEA 4H8SA 2DKPA 1DDVA 1XR0B 2Z0PA 1DDWA 4KHAA 1N3HA 3M1IB 5JLJB 2YS5A 1FOEA 2J0KA 2VKIA 1X05A 3VIAA 3TCAA 1ZSQA 1ZM0A 2CRFA 2UZSA 2Z0OA 4Z2NA 2LKOA 2AEHA 2YS1A 1BTKA 2YT1A 1NTYA 3TO1A 2VSZA 5D3VA 1V5UA 2JP2A 3D8DA 2LG1A 4F7HA 3A98B 2J0JA 4HAVB 3SNHA 1UNPA 4K17A 3PEGA 5C5BB 1FAOA 1KZ7A 2OTXA 4IAPA 2J0MA 1GC7A 2ELBA 1V5MA 4Y94A 3BINA 4MK0A 2MDXA 3QWMA 2UVMA 3DXCA 4MT7A 1U29A 2DX1A 4GMXB 2I1KA 2DHJA 5KCVA 4A6KA 1AQCA 2RUKB 1J0WA 1WJMA 4GZUA 2RLOA 4KHOA 5JHHA 2DN6A 5C6RA 4ZRJA 1UPQA 2D9VA 2AL6A 3A8PA 2N23A 4XWXA 1M7RA 3F0WA 2P0FA 3U8ZA 3ODOA 1QC6A 2DA0A 2GJYA 1BTNA 4HDOA 1V88A 2H7DA 1XKEA 2I5FA 3ZVRA 5HE3A 2OQBA 2M14A 2R09A 4PNKA 1XODA 1UNRA 2K00A 3KY9A 1GC6A 1V5PA 1EF1A 2NMBA 5CLLB 2IFSA 1WI1A 1U27A 5CLQB 1J19A 1ZVRA 5FI0A 2CY5A 5D3XA 1RRPB 3D8EA 4ZRKA 3F5RA 4Z2MB 2VRWB 2I5CA 3VOQA 1W1DA 2N0YA 5DHAB 2LULA 3ML4A 1I2HA 4HAYB 1FHOA 2YF0A 2EJ8A 2Y8GA 2DHIA 4HDQA 4EMOA 3KZ1A 2P0HA 3O96A 5C79A 2RNRB 3OANA 4WJ7A 3X23A 1X11A 1Z87A 2D2QA 4A6FA 5LONB 2FJLA 1OY2A 2EMSA 3MPXA 2DLWA 3N7CA 1WJ1A 1XCGA 4D0NB 1NTVA 5DI9B 2PZ1A 4ZRIA 1U5EA 3GYPA 3TW1A 4CYEA 2D9ZA 1W1HA 3QBVB 3IVFA 1PLSA 4DX90 1UPRA 1FB8A 2KGXB 1XD4A 1U5GA 3RCPA 5J3TA 1TJ6A 3SYXA 1EGXA 5J3YA 3PVWA 5D3YA 4DBBA 1RJ2A 3SUZA 4DX8A 1OQNA 3P6AA 4GPTB 1UNQA 3ZDTA 2ZPYA 4A5KA 4DXAB 4B6HA 4CHMA 1DDMA 3PP2A 1U2BA 3AJ4A 2ELAA 4EKUA 1ZC4B 1MK7B 1W1GA 4GMVA 2D9YA 4PQ0A 3DXEA 2YS3A 3HQCA 3TFMA 2GCJA 2DHKA 4WVFB 3P7ZA 2YSZA 1UEFA 2R0DA 4P7IA 3QIJA 1K5DB 1H10A 4A6HA 3SO6A 2GCLA 3WA0A 4HAWB 1U5FA 1TXDA 1B55A 2H7EA 5J3QA 2X18A 1PMSA 1SHCA 2E2XA 3T06A 4F7UP 4YONA 3CXBB 2HE7A 1PFJA 1ZC3B 3SV1A 4HB2B 2NZ8B 3ULCA 4HATB 1KI1B 4BBKA 2LOXA 1Q67A 1P5TA 1DYNA 1ISNA 4EJNA 2I1JA 3PZDA 2DKQA 5C16A 2RVBB 1MAIA 4TKNA 1V61A 2Y7BA 4KAXB 2QKMA 4HB3B 2V76A 2D10A 2UZRA 2MWNB 5DHFB 2LOZA 3PG7A 2M38A 2W2XD 3FSSA 4MY6A 3WYFB 3D8FA 4F7GA 5JHGA 1Y19B 1WGQA 1MPHA 2P0DA 4YL8A 4HB0B 1SGHA 1KZGA 2L2IA 1WVHA 3HW2B 3ODXA 3AU4A 1XX0A 4K2PA 5DIFB 3UZTA 1V89A 1NU2A 2KUPA 2DYQA 5EFXA 2Y8FA 2IYBA 3KRWA 1X1GA 2J59M 2EC1A 2P8VA 2D4QA 1I7AA 1NI2A 2MFQA 5L81A 4L6EA 5C5BA 3PVLA 4HB4B 3FEHA 1WGUA 1FGYA 4IOYX 1Y5OA 2GS0A 4NSWA 4HAUB 4HHVA 1DBHA 1EVHA 2ROZB 3DXDA 2YT0A 4KHBB 3KRXA 4IFSA 3PVUA 2QKLA 3BJIA 2D9WA 2ROVA 2W2XC 1MKEA 4A6FB 3A8QA 1FHXA 1X86A 3TVVA 1U5DA 1H4RA 1K5GB 4HAXB 5KQ4A 4K81A 1GG3A 5DH9B 2CY4A 5HE0A 2COCA 2CODA 3ULBA 5JP4A 2YVCA 3CIKA 2D9XA 2Z0QA 2DYNA 2COAA 4KVGB 4C0AA 3ODWA 2DX5A 1OMWA 5FI1A 5HE2A 3KSYA 1IRSA 4HAZB 3FM8C 2K2JA 2YRYA 3PSCA 4GXBA 1E5WA 3GYOA 2HTHB 4GN1A 4TYZA 2EMTA 4WSFA 4NY0A 2RGNB 2COFA 2W2WA 3NSUA 2K2UA 2XQNM 5GOWB 1X1FA 1EAZA 2LYDA 3G9WA 3MDBC 1P3RA 1MK9B 2KCJA 1MIXA 1BAKA 1TQZA 4CHJA 5D27A 2RSGA 2D11A 1P6SA 3V5WA 5D3WA 2DFKA 1WG7A 1M7EA 5HE1A 2MKRA 4K2OA 2Q13A 3AU5A 1QQGA
chains in the Genus database with same CATH superfamily
2DTCA 1BWNA 2ADZA 2L1CA 1FHWA 3LJUX 2BCJA 5LOPB 1LB1A 4CSQA 1FGZA 3U7DA 3A58A 2CAYA 2G35A 5LG4B 3HK0A 1LW3A 1DROA 5KQ1A 1MIZB 1AWEA 4H8SA 2DKPA 1DDVA 1XR0B 2Z0PA 1DDWA 4KHAA 1N3HA 3M1IB 5JLJB 2YS5A 1FOEA 2J0KA 2VKIA 1X05A 3VIAA 3U12A 3TCAA 2Z14A 1ZSQA 1ZM0A 2CRFA 2UZSA 2Z0OA 4Z2NA 2LKOA 2AEHA 2YS1A 1BTKA 2YT1A 1NTYA 3TO1A 2VSZA 5D3VA 1V5UA 2JP2A 3D8DA 2LG1A 4F7HA 3A98B 2J0JA 4HAVB 3SNHA 1UNPA 4K17A 2YT2A 4OT1A 3PEGA 5C5BB 1FAOA 1KZ7A 2OTXA 4IAPA 1T77A 2J0MA 1GC7A 2ELBA 1V5MA 4Y94A 3BINA 4MK0A 2MDXA 3QWMA 2UVMA 3DXCA 4MT7A 1U29A 2DX1A 4GMXB 2I1KA 2DHJA 5KCVA 4A6KA 1AQCA 2RUKB 3HSAA 3FVCA 1J0WA 1WJMA 4GZUA 2RLOA 4KHOA 5JHHA 2DN6A 5C6RA 4ZRJA 1UPQA 2D9VA 2AL6A 3A8PA 2N23A 4XWXA 2KUQA 1M7RA 3F0WA 2KIGA 2P0FA 3U8ZA 3ODOA 1QC6A 2DA0A 2GJYA 1BTNA 4QJ5B 4HDOA 1V88A 2H7DA 1XKEA 2I5FA 3NWFA 3ZVRA 5HE3A 3NWAA 2OQBA 2M14A 2R09A 4PNKA 1XODA 3NW8A 1UNRA 2K00A 3KY9A 1GC6A 1V5PA 1EF1A 2NMBA 5CLLB 2IFSA 1WI1A 1U27A 2K8EA 5CLQB 1J19A 3OHMB 1ZVRA 5FI0A 2CY5A 4DIXA 5D3XA 1RRPB 3D8EA 4ZRKA 3F5RA 4Z2MB 2VRWB 2I5CA 3VOQA 1W1DA 2N0YA 5DHAB 5I2SA 2LULA 3ML4A 1I2HA 4HAYB 1FHOA 2YF0A 2EJ8A 2Y8GA 2GUMA 2DHIA 4HDQA 4EMOA 4QXAB 3KZ1A 4KHBA 2P0HA 3O96A 5C79A 2RNRB 3OANA 4WJ7A 3X23A 1X11A 1Z87A 2D2QA 4A6FA 5LONB 2FJLA 1OY2A 2EMSA 3MPXA 2DLWA 3N7CA 1WJ1A 1XCGA 2Z13A 4D0NB 1NTVA 5DI9B 2PZ1A 2Z59A 2Z4DA 1U5EA 3GYPA 4ZRIA 3TW1A 4CYEA 2D9ZA 1W1HA 3NWDA 3QBVB 3IVFA 1PLSA 4DX90 1UPRA 4D6WA 1FB8A 2KGXB 1XD4A 1U5GA 3RCPA 5J3TA 1TJ6A 3SYXA 3DCXA 1EGXA 5J3YA 3PVWA 5D3YA 4DBBA 1RJ2A 3SUZA 2FJUB 1OQNA 4DX8A 3P6AA 4GPTB 1UNQA 3ZDTA 2ZPYA 4A5KA 4DXAB 4B6HA 4CHMA 1DDMA 3PP2A 1U2BA 3AJ4A 2ELAA 4EKUA 1ZC4B 1MK7B 1W1GA 4GMVA 2D9YA 4PQ0A 3DXEA 2YS3A 3HQCA 3TFMA 2GCJA 4QJ3B 2DHKA 4WVFB 3P7ZA 4OSNA 2YSZA 1UEFA 2R0DA 4P7IA 3QIJA 1K5DB 1H10A 4A6HA 3SO6A 2GCLA 3WA0A 4HAWB 1U5FA 1TXDA 1B55A 2H7EA 5J3QA 2X18A 1PMSA 1SHCA 2E2XA 3T06A 4F7UP 4YONA 3CXBB 2HE7A 1PFJA 1ZC3B 3SV1A 4HB2B 2NZ8B 3ULCA 4HATB 1KI1B 4BBKA 2LOXA 1Q67A 1P5TA 1DYNA 4QJ4B 1ISNA 4EJNA 2I1JA 3PZDA 2DKQA 5C16A 2RVBB 1MAIA 4TKNA 1V61A 2Y7BA 4KAXB 2QKMA 4HB3B 2ZKMX 2V76A 2D10A 2KIEA 2UZRA 2MWNB 5DHFB 2LOZA 1MI1A 3PG7A 2M38A 2W2XD 3FSSA 4MY6A 3WYFB 3D8FA 4F7GA 5JHGA 1Y19B 1WGQA 1MPHA 2P0DA 4YL8A 4HB0B 1SGHA 1KZGA 2L2IA 1WVHA 3HW2B 3ODXA 3AU4A 1XX0A 4K2PA 5DIFB 3UZTA 1V89A 5I2MA 1NU2A 2KUPA 2DYQA 5EFXA 3B77A 2Y8FA 2IYBA 3KRWA 1X1GA 2J59M 2EC1A 2P8VA 2D4QA 1I7AA 1NI2A 2MFQA 2R2YA 5L81A 4L6EA 5C5BA 3PVLA 4HB4B 3FEHA 1WGUA 1FGYA 4GNKB 4IOYX 1Y5OA 2RRFA 2GS0A 4NSWA 4HAUB 4HHVA 1DBHA 1EVHA 2ROZB 3DXDA 4L1RA 2YT0A 4KHBB 3KRXA 4IFSA 3PVUA 2QKLA 3BJIA 5IRSA 5M4YB 2D9WA 2ROVA 2W2XC 1MKEA 4A6FB 3A8QA 2K49A 1FHXA 1X86A 4HSIA 3TVVA 1U5DA 1H4RA 1K5GB 4HAXB 5KQ4A 4K81A 1GG3A 5DH9B 2CY4A 5HE0A 2COCA 2CODA 3ULBA 5JP4A 2YVCA 3CIKA 2D9XA 2Z0QA 2DYNA 2COAA 4KVGB 4C0AA 3ODWA 2DX5A 1OMWA 1ZYIA 5FI1A 5HE2A 3KSYA 1IRSA 4HAZB 3FM8C 2K2JA 2YRYA 3PSCA 4GXBA 4GOUA 1E5WA 3GYOA 2HTHB 4GN1A 4TYZA 2EMTA 4WSFA 4NY0A 2RGNB 2COFA 2W2WA 3NSUA 2K2UA 2XQNM 5GOWB 1X1FA 1EAZA 2LYDA 3G9WA 3MDBC 1P3RA 1MK9B 2KR0A 2KCJA 1MIXA 3HIEA 1BAKA 1TQZA 4CHJA 5D27A 2RSGA 2D11A 1P6SA 3V5WA 5D3WA 2DFKA 1WG7A 1M7EA 5HE1A 2MKRA 4K2OA 2Q13A 2NBVA 3AU5A 1QQGA
chains in the Genus database with same CATH topology
2DTCA 1BWNA 2ADZA 2L1CA 1FHWA 3LJUX 2BCJA 5LOPB 1LB1A 1FGZA 3U7DA 2CAYA 2G35A 3HK0A 1LW3A 1DROA 5KQ1A 1MIZB 1AWEA 4H8SA 2DKPA 1DDVA 1XR0B 2Z0PA 1DDWA 4KHAA 1N3HA 3M1IB 5JLJB 2YS5A 1FOEA 2J0KA 2VKIA 1X05A 3VIAA 3TCAA 1ZSQA 1ZM0A 2CRFA 2UZSA 2Z0OA 4Z2NA 2LKOA 2AEHA 2YS1A 1BTKA 2YT1A 1NTYA 3TO1A 2VSZA 5D3VA 1V5UA 2JP2A 3D8DA 2LG1A 4F7HA 3A98B 2J0JA 4HAVB 3SNHA 1UNPA 4K17A 3PEGA 5C5BB 1FAOA 1KZ7A 2OTXA 4IAPA 2J0MA 1GC7A 2ELBA 1V5MA 4Y94A 3BINA 4MK0A 2MDXA 3QWMA 2UVMA 3DXCA 4MT7A 1U29A 2DX1A 4GMXB 2I1KA 2DHJA 5KCVA 4A6KA 1AQCA 2RUKB 1J0WA 1WJMA 4GZUA 2RLOA 4KHOA 5JHHA 2DN6A 5C6RA 4ZRJA 1UPQA 2D9VA 2AL6A 3A8PA 2N23A 4XWXA 1M7RA 3F0WA 2P0FA 3U8ZA 3ODOA 1QC6A 2DA0A 2GJYA 1BTNA 4HDOA 1V88A 2H7DA 1XKEA 2I5FA 3ZVRA 5HE3A 2OQBA 2M14A 2R09A 4PNKA 1XODA 1UNRA 2K00A 3KY9A 1GC6A 1V5PA 1EF1A 2NMBA 5CLLB 2IFSA 1WI1A 1U27A 5CLQB 1J19A 1ZVRA 5FI0A 2CY5A 5D3XA 1RRPB 3D8EA 4ZRKA 3F5RA 4Z2MB 2VRWB 2I5CA 3VOQA 1W1DA 2N0YA 5DHAB 2LULA 3ML4A 1I2HA 4HAYB 1FHOA 2YF0A 2EJ8A 2Y8GA 2DHIA 4HDQA 4EMOA 3KZ1A 2P0HA 3O96A 5C79A 2RNRB 3OANA 4WJ7A 3X23A 1X11A 1Z87A 2D2QA 4A6FA 5LONB 2FJLA 1OY2A 2EMSA 3MPXA 2DLWA 3N7CA 1WJ1A 1XCGA 4D0NB 1NTVA 5DI9B 2PZ1A 4ZRIA 1U5EA 3GYPA 3TW1A 4CYEA 2D9ZA 1W1HA 3QBVB 3IVFA 1PLSA 4DX90 1UPRA 1FB8A 2KGXB 1XD4A 1U5GA 3RCPA 5J3TA 1TJ6A 3SYXA 1EGXA 5J3YA 3PVWA 5D3YA 4DBBA 1RJ2A 3SUZA 4DX8A 1OQNA 3P6AA 4GPTB 1UNQA 3ZDTA 2ZPYA 4A5KA 4DXAB 4B6HA 4CHMA 1DDMA 3PP2A 1U2BA 3AJ4A 2ELAA 4EKUA 1ZC4B 1MK7B 1W1GA 4GMVA 2D9YA 4PQ0A 3DXEA 2YS3A 3HQCA 3TFMA 2GCJA 2DHKA 4WVFB 3P7ZA 2YSZA 1UEFA 2R0DA 4P7IA 3QIJA 1K5DB 1H10A 4A6HA 3SO6A 2GCLA 3WA0A 4HAWB 1U5FA 1TXDA 1B55A 2H7EA 5J3QA 2X18A 1PMSA 1SHCA 2E2XA 3T06A 4F7UP 4YONA 3CXBB 2HE7A 1PFJA 1ZC3B 3SV1A 4HB2B 2NZ8B 3ULCA 4HATB 1KI1B 4BBKA 2LOXA 1Q67A 1P5TA 1DYNA 1ISNA 4EJNA 2I1JA 3PZDA 2DKQA 5C16A 2RVBB 1MAIA 4TKNA 1V61A 2Y7BA 4KAXB 2QKMA 4HB3B 2V76A 2D10A 2UZRA 2MWNB 5DHFB 2LOZA 3PG7A 2M38A 2W2XD 3FSSA 4MY6A 3WYFB 3D8FA 4F7GA 5JHGA 1Y19B 1WGQA 1MPHA 2P0DA 4YL8A 4HB0B 1SGHA 1KZGA 2L2IA 1WVHA 3HW2B 3ODXA 3AU4A 1XX0A 4K2PA 5DIFB 3UZTA 1V89A 1NU2A 2KUPA 2DYQA 5EFXA 2Y8FA 2IYBA 3KRWA 1X1GA 2J59M 2EC1A 2P8VA 2D4QA 1I7AA 1NI2A 2MFQA 5L81A 4L6EA 5C5BA 3PVLA 4HB4B 3FEHA 1WGUA 1FGYA 4IOYX 1Y5OA 2GS0A 4NSWA 4HAUB 4HHVA 1DBHA 1EVHA 2ROZB 3DXDA 2YT0A 4KHBB 3KRXA 4IFSA 3PVUA 2QKLA 3BJIA 2D9WA 2ROVA 2W2XC 1MKEA 4A6FB 3A8QA 1FHXA 1X86A 3TVVA 1U5DA 1H4RA 1K5GB 4HAXB 5KQ4A 4K81A 1GG3A 5DH9B 2CY4A 5HE0A 2COCA 2CODA 3ULBA 5JP4A 2YVCA 3CIKA 2D9XA 2Z0QA 2DYNA 2COAA 4KVGB 4C0AA 3ODWA 2DX5A 1OMWA 5FI1A 5HE2A 3KSYA 1IRSA 4HAZB 3FM8C 2K2JA 2YRYA 3PSCA 4GXBA 1E5WA 3GYOA 2HTHB 4GN1A 4TYZA 2EMTA 4WSFA 4NY0A 2RGNB 2COFA 2W2WA 3NSUA 2K2UA 2XQNM 5GOWB 1X1FA 1EAZA 2LYDA 3G9WA 3MDBC 1P3RA 1MK9B 2KCJA 1MIXA 1BAKA 1TQZA 4CHJA 5D27A 2RSGA 2D11A 1P6SA 3V5WA 5D3WA 2DFKA 1WG7A 1M7EA 5HE1A 2MKRA 4K2OA 2Q13A 3AU5A 1QQGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DTC A;  1BWN A;  2ADZ A;  2L1C A;  1FHW A;  3LJU X;  2BCJ A;  5LOP B;  1LB1 A;  1FGZ A;  3U7D A;  2CAY A;  2G35 A;  3HK0 A;  1LW3 A;  1DRO A;  5KQ1 A;  1MIZ B;  1AWE A;  4H8S A;  2DKP A;  1DDV A;  1XR0 B;  2Z0P A;  1DDW A;  4KHA A;  1N3H A;  3M1I B;  5JLJ B;  2YS5 A;  1FOE A;  2J0K A;  2VKI A;  1X05 A;  3VIA A;  3TCA A;  1ZSQ A;  1ZM0 A;  2CRF A;  2UZS A;  2Z0O A;  4Z2N A;  2LKO A;  2AEH A;  2YS1 A;  1BTK A;  2YT1 A;  1NTY A;  3TO1 A;  2VSZ A;  5D3V A;  1V5U A;  2JP2 A;  3D8D A;  2LG1 A;  4F7H A;  3A98 B;  2J0J A;  4HAV B;  3SNH A;  1UNP A;  4K17 A;  3PEG A;  5C5B B;  1FAO A;  1KZ7 A;  2OTX A;  4IAP A;  2J0M A;  1GC7 A;  2ELB A;  1V5M A;  4Y94 A;  3BIN A;  4MK0 A;  2MDX A;  3QWM A;  2UVM A;  3DXC A;  4MT7 A;  1U29 A;  2DX1 A;  4GMX B;  2I1K A;  2DHJ A;  5KCV A;  4A6K A;  1AQC A;  2RUK B;  1J0W A;  1WJM A;  4GZU A;  2RLO A;  4KHO A;  5JHH A;  2DN6 A;  5C6R A;  4ZRJ A;  1UPQ A;  2D9V A;  2AL6 A;  3A8P A;  2N23 A;  4XWX A;  1M7R A;  3F0W A;  2P0F A;  3U8Z A;  3ODO A;  1QC6 A;  2DA0 A;  2GJY A;  1BTN A;  4HDO A;  1V88 A;  2H7D A;  1XKE A;  2I5F A;  3ZVR A;  5HE3 A;  2OQB A;  2M14 A;  2R09 A;  4PNK A;  1XOD A;  1UNR A;  2K00 A;  3KY9 A;  1GC6 A;  1V5P A;  1EF1 A;  2NMB A;  5CLL B;  2IFS A;  1WI1 A;  1U27 A;  5CLQ B;  1J19 A;  1ZVR A;  5FI0 A;  2CY5 A;  5D3X A;  1RRP B;  3D8E A;  4ZRK A;  3F5R A;  4Z2M B;  2VRW B;  2I5C A;  3VOQ A;  1W1D A;  2N0Y A;  5DHA B;  2LUL A;  3ML4 A;  1I2H A;  4HAY B;  1FHO A;  2YF0 A;  2EJ8 A;  2Y8G A;  2DHI A;  4HDQ A;  4EMO A;  3KZ1 A;  2P0H A;  3O96 A;  5C79 A;  2RNR B;  3OAN A;  4WJ7 A;  3X23 A;  1X11 A;  1Z87 A;  2D2Q A;  4A6F A;  5LON B;  2FJL A;  1OY2 A;  2EMS A;  3MPX A;  2DLW A;  3N7C A;  1WJ1 A;  1XCG A;  4D0N B;  1NTV A;  5DI9 B;  2PZ1 A;  4ZRI A;  1U5E A;  3GYP A;  3TW1 A;  4CYE A;  2D9Z A;  1W1H A;  3QBV B;  3IVF A;  1PLS A;  4DX9 0;  1UPR A;  1FB8 A;  2KGX B;  1XD4 A;  1U5G A;  3RCP A;  5J3T A;  1TJ6 A;  3SYX A;  1EGX A;  5J3Y A;  3PVW A;  5D3Y A;  4DBB A;  1RJ2 A;  3SUZ A;  4DX8 A;  1OQN A;  3P6A A;  4GPT B;  1UNQ A;  3ZDT A;  2ZPY A;  4A5K A;  4DXA B;  4B6H A;  4CHM A;  1DDM A;  3PP2 A;  1U2B A;  3AJ4 A;  2ELA A;  4EKU A;  1ZC4 B;  1MK7 B;  1W1G A;  4GMV A;  2D9Y A;  4PQ0 A;  3DXE A;  2YS3 A;  3HQC A;  3TFM A;  2GCJ A;  2DHK A;  4WVF B;  3P7Z A;  2YSZ A;  1UEF A;  2R0D A;  4P7I A;  3QIJ A;  1K5D B;  1H10 A;  4A6H A;  3SO6 A;  2GCL A;  3WA0 A;  4HAW B;  1U5F A;  1TXD A;  1B55 A;  2H7E A;  5J3Q A;  2X18 A;  1PMS A;  1SHC A;  2E2X A;  3T06 A;  4F7U P;  4YON A;  3CXB B;  2HE7 A;  1PFJ A;  1ZC3 B;  3SV1 A;  4HB2 B;  2NZ8 B;  3ULC A;  4HAT B;  1KI1 B;  4BBK A;  2LOX A;  1Q67 A;  1P5T A;  1DYN A;  1ISN A;  4EJN A;  2I1J A;  3PZD A;  2DKQ A;  5C16 A;  2RVB B;  1MAI A;  4TKN A;  1V61 A;  2Y7B A;  4KAX B;  2QKM A;  4HB3 B;  2V76 A;  2D10 A;  2UZR A;  2MWN B;  5DHF B;  2LOZ A;  3PG7 A;  2M38 A;  2W2X D;  3FSS A;  4MY6 A;  3WYF B;  3D8F A;  4F7G A;  5JHG A;  1Y19 B;  1WGQ A;  1MPH A;  2P0D A;  4YL8 A;  4HB0 B;  1SGH A;  1KZG A;  2L2I A;  1WVH A;  3HW2 B;  3ODX A;  3AU4 A;  1XX0 A;  4K2P A;  5DIF B;  3UZT A;  1V89 A;  1NU2 A;  2KUP A;  2DYQ A;  5EFX A;  2Y8F A;  2IYB A;  3KRW A;  1X1G A;  2J59 M;  2EC1 A;  2P8V A;  2D4Q A;  1I7A A;  1NI2 A;  2MFQ A;  5L81 A;  4L6E A;  5C5B A;  3PVL A;  4HB4 B;  3FEH A;  1WGU A;  1FGY A;  4IOY X;  1Y5O A;  2GS0 A;  4NSW A;  4HAU B;  4HHV A;  1DBH A;  1EVH A;  2ROZ B;  3DXD A;  2YT0 A;  4KHB B;  3KRX A;  4IFS A;  3PVU A;  2QKL A;  3BJI A;  2D9W A;  2ROV A;  2W2X C;  1MKE A;  4A6F B;  3A8Q A;  1FHX A;  1X86 A;  3TVV A;  1U5D A;  1H4R A;  1K5G B;  4HAX B;  5KQ4 A;  4K81 A;  1GG3 A;  5DH9 B;  2CY4 A;  5HE0 A;  2COC A;  2COD A;  3ULB A;  5JP4 A;  2YVC A;  3CIK A;  2D9X A;  2Z0Q A;  2DYN A;  2COA A;  4KVG B;  4C0A A;  3ODW A;  2DX5 A;  1OMW A;  5FI1 A;  5HE2 A;  3KSY A;  1IRS A;  4HAZ B;  3FM8 C;  2K2J A;  2YRY A;  3PSC A;  4GXB A;  1E5W A;  3GYO A;  2HTH B;  4GN1 A;  4TYZ A;  2EMT A;  4WSF A;  4NY0 A;  2RGN B;  2COF A;  2W2W A;  3NSU A;  2K2U A;  2XQN M;  5GOW B;  1X1F A;  1EAZ A;  2LYD A;  3G9W A;  3MDB C;  1P3R A;  1MK9 B;  2KCJ A;  1MIX A;  1BAK A;  1TQZ A;  4CHJ A;  5D27 A;  2RSG A;  2D11 A;  1P6S A;  3V5W A;  5D3W A;  2DFK A;  1WG7 A;  1M7E A;  5HE1 A;  2MKR A;  4K2O A;  2Q13 A;  3AU5 A;  1QQG A; 
#chains in the Genus database with same CATH topology
 2DTC A;  1BWN A;  2ADZ A;  2L1C A;  1FHW A;  3LJU X;  2BCJ A;  5LOP B;  1LB1 A;  4CSQ A;  1FGZ A;  3U7D A;  3A58 A;  2CAY A;  2G35 A;  5LG4 B;  3HK0 A;  1LW3 A;  1DRO A;  5KQ1 A;  1MIZ B;  1AWE A;  4H8S A;  2DKP A;  1DDV A;  1XR0 B;  2Z0P A;  1DDW A;  4KHA A;  1N3H A;  3M1I B;  5JLJ B;  2YS5 A;  1FOE A;  2J0K A;  2VKI A;  1X05 A;  3VIA A;  3U12 A;  3TCA A;  2Z14 A;  1ZSQ A;  1ZM0 A;  2CRF A;  2UZS A;  2Z0O A;  4Z2N A;  2LKO A;  2AEH A;  2YS1 A;  1BTK A;  2YT1 A;  1NTY A;  3TO1 A;  2VSZ A;  5D3V A;  1V5U A;  2JP2 A;  3D8D A;  2LG1 A;  4F7H A;  3A98 B;  2J0J A;  4HAV B;  3SNH A;  1UNP A;  4K17 A;  2YT2 A;  4OT1 A;  3PEG A;  5C5B B;  1FAO A;  1KZ7 A;  2OTX A;  4IAP A;  1T77 A;  2J0M A;  1GC7 A;  2ELB A;  1V5M A;  4Y94 A;  3BIN A;  4MK0 A;  2MDX A;  3QWM A;  2UVM A;  3DXC A;  4MT7 A;  1U29 A;  2DX1 A;  4GMX B;  2I1K A;  2DHJ A;  5KCV A;  4A6K A;  1AQC A;  2RUK B;  3HSA A;  3FVC A;  1J0W A;  1WJM A;  4GZU A;  2RLO A;  4KHO A;  5JHH A;  2DN6 A;  5C6R A;  4ZRJ A;  1UPQ A;  2D9V A;  2AL6 A;  3A8P A;  2N23 A;  4XWX A;  2KUQ A;  1M7R A;  3F0W A;  2KIG A;  2P0F A;  3U8Z A;  3ODO A;  1QC6 A;  2DA0 A;  2GJY A;  1BTN A;  4QJ5 B;  4HDO A;  1V88 A;  2H7D A;  1XKE A;  2I5F A;  3NWF A;  3ZVR A;  5HE3 A;  3NWA A;  2OQB A;  2M14 A;  2R09 A;  4PNK A;  1XOD A;  3NW8 A;  1UNR A;  2K00 A;  3KY9 A;  1GC6 A;  1V5P A;  1EF1 A;  2NMB A;  5CLL B;  2IFS A;  1WI1 A;  1U27 A;  2K8E A;  5CLQ B;  1J19 A;  3OHM B;  1ZVR A;  5FI0 A;  2CY5 A;  4DIX A;  5D3X A;  1RRP B;  3D8E A;  4ZRK A;  3F5R A;  4Z2M B;  2VRW B;  2I5C A;  3VOQ A;  1W1D A;  2N0Y A;  5DHA B;  5I2S A;  2LUL A;  3ML4 A;  1I2H A;  4HAY B;  1FHO A;  2YF0 A;  2EJ8 A;  2Y8G A;  2GUM A;  2DHI A;  4HDQ A;  4EMO A;  4QXA B;  3KZ1 A;  4KHB A;  2P0H A;  3O96 A;  5C79 A;  2RNR B;  3OAN A;  4WJ7 A;  3X23 A;  1X11 A;  1Z87 A;  2D2Q A;  4A6F A;  5LON B;  2FJL A;  1OY2 A;  2EMS A;  3MPX A;  2DLW A;  3N7C A;  1WJ1 A;  1XCG A;  2Z13 A;  4D0N B;  1NTV A;  5DI9 B;  2PZ1 A;  2Z59 A;  2Z4D A;  1U5E A;  3GYP A;  4ZRI A;  3TW1 A;  4CYE A;  2D9Z A;  1W1H A;  3NWD A;  3QBV B;  3IVF A;  1PLS A;  4DX9 0;  1UPR A;  4D6W A;  1FB8 A;  2KGX B;  1XD4 A;  1U5G A;  3RCP A;  5J3T A;  1TJ6 A;  3SYX A;  3DCX A;  1EGX A;  5J3Y A;  3PVW A;  5D3Y A;  4DBB A;  1RJ2 A;  3SUZ A;  2FJU B;  1OQN A;  4DX8 A;  3P6A A;  4GPT B;  1UNQ A;  3ZDT A;  2ZPY A;  4A5K A;  4DXA B;  4B6H A;  4CHM A;  1DDM A;  3PP2 A;  1U2B A;  3AJ4 A;  2ELA A;  4EKU A;  1ZC4 B;  1MK7 B;  1W1G A;  4GMV A;  2D9Y A;  4PQ0 A;  3DXE A;  2YS3 A;  3HQC A;  3TFM A;  2GCJ A;  4QJ3 B;  2DHK A;  4WVF B;  3P7Z A;  4OSN A;  2YSZ A;  1UEF A;  2R0D A;  4P7I A;  3QIJ A;  1K5D B;  1H10 A;  4A6H A;  3SO6 A;  2GCL A;  3WA0 A;  4HAW B;  1U5F A;  1TXD A;  1B55 A;  2H7E A;  5J3Q A;  2X18 A;  1PMS A;  1SHC A;  2E2X A;  3T06 A;  4F7U P;  4YON A;  3CXB B;  2HE7 A;  1PFJ A;  1ZC3 B;  3SV1 A;  4HB2 B;  2NZ8 B;  3ULC A;  4HAT B;  1KI1 B;  4BBK A;  2LOX A;  1Q67 A;  1P5T A;  1DYN A;  4QJ4 B;  1ISN A;  4EJN A;  2I1J A;  3PZD A;  2DKQ A;  5C16 A;  2RVB B;  1MAI A;  4TKN A;  1V61 A;  2Y7B A;  4KAX B;  2QKM A;  4HB3 B;  2ZKM X;  2V76 A;  2D10 A;  2KIE A;  2UZR A;  2MWN B;  5DHF B;  2LOZ A;  1MI1 A;  3PG7 A;  2M38 A;  2W2X D;  3FSS A;  4MY6 A;  3WYF B;  3D8F A;  4F7G A;  5JHG A;  1Y19 B;  1WGQ A;  1MPH A;  2P0D A;  4YL8 A;  4HB0 B;  1SGH A;  1KZG A;  2L2I A;  1WVH A;  3HW2 B;  3ODX A;  3AU4 A;  1XX0 A;  4K2P A;  5DIF B;  3UZT A;  1V89 A;  5I2M A;  1NU2 A;  2KUP A;  2DYQ A;  5EFX A;  3B77 A;  2Y8F A;  2IYB A;  3KRW A;  1X1G A;  2J59 M;  2EC1 A;  2P8V A;  2D4Q A;  1I7A A;  1NI2 A;  2MFQ A;  2R2Y A;  5L81 A;  4L6E A;  5C5B A;  3PVL A;  4HB4 B;  3FEH A;  1WGU A;  1FGY A;  4GNK B;  4IOY X;  1Y5O A;  2RRF A;  2GS0 A;  4NSW A;  4HAU B;  4HHV A;  1DBH A;  1EVH A;  2ROZ B;  3DXD A;  4L1R A;  2YT0 A;  4KHB B;  3KRX A;  4IFS A;  3PVU A;  2QKL A;  3BJI A;  5IRS A;  5M4Y B;  2D9W A;  2ROV A;  2W2X C;  1MKE A;  4A6F B;  3A8Q A;  2K49 A;  1FHX A;  1X86 A;  4HSI A;  3TVV A;  1U5D A;  1H4R A;  1K5G B;  4HAX B;  5KQ4 A;  4K81 A;  1GG3 A;  5DH9 B;  2CY4 A;  5HE0 A;  2COC A;  2COD A;  3ULB A;  5JP4 A;  2YVC A;  3CIK A;  2D9X A;  2Z0Q A;  2DYN A;  2COA A;  4KVG B;  4C0A A;  3ODW A;  2DX5 A;  1OMW A;  1ZYI A;  5FI1 A;  5HE2 A;  3KSY A;  1IRS A;  4HAZ B;  3FM8 C;  2K2J A;  2YRY A;  3PSC A;  4GXB A;  4GOU A;  1E5W A;  3GYO A;  2HTH B;  4GN1 A;  4TYZ A;  2EMT A;  4WSF A;  4NY0 A;  2RGN B;  2COF A;  2W2W A;  3NSU A;  2K2U A;  2XQN M;  5GOW B;  1X1F A;  1EAZ A;  2LYD A;  3G9W A;  3MDB C;  1P3R A;  1MK9 B;  2KR0 A;  2KCJ A;  1MIX A;  3HIE A;  1BAK A;  1TQZ A;  4CHJ A;  5D27 A;  2RSG A;  2D11 A;  1P6S A;  3V5W A;  5D3W A;  2DFK A;  1WG7 A;  1M7E A;  5HE1 A;  2MKR A;  4K2O A;  2Q13 A;  2NBV A;  3AU5 A;  1QQG A; 
#chains in the Genus database with same CATH homology
 2DTC A;  1BWN A;  2ADZ A;  2L1C A;  1FHW A;  3LJU X;  2BCJ A;  5LOP B;  1LB1 A;  1FGZ A;  3U7D A;  2CAY A;  2G35 A;  3HK0 A;  1LW3 A;  1DRO A;  5KQ1 A;  1MIZ B;  1AWE A;  4H8S A;  2DKP A;  1DDV A;  1XR0 B;  2Z0P A;  1DDW A;  4KHA A;  1N3H A;  3M1I B;  5JLJ B;  2YS5 A;  1FOE A;  2J0K A;  2VKI A;  1X05 A;  3VIA A;  3TCA A;  1ZSQ A;  1ZM0 A;  2CRF A;  2UZS A;  2Z0O A;  4Z2N A;  2LKO A;  2AEH A;  2YS1 A;  1BTK A;  2YT1 A;  1NTY A;  3TO1 A;  2VSZ A;  5D3V A;  1V5U A;  2JP2 A;  3D8D A;  2LG1 A;  4F7H A;  3A98 B;  2J0J A;  4HAV B;  3SNH A;  1UNP A;  4K17 A;  3PEG A;  5C5B B;  1FAO A;  1KZ7 A;  2OTX A;  4IAP A;  2J0M A;  1GC7 A;  2ELB A;  1V5M A;  4Y94 A;  3BIN A;  4MK0 A;  2MDX A;  3QWM A;  2UVM A;  3DXC A;  4MT7 A;  1U29 A;  2DX1 A;  4GMX B;  2I1K A;  2DHJ A;  5KCV A;  4A6K A;  1AQC A;  2RUK B;  1J0W A;  1WJM A;  4GZU A;  2RLO A;  4KHO A;  5JHH A;  2DN6 A;  5C6R A;  4ZRJ A;  1UPQ A;  2D9V A;  2AL6 A;  3A8P A;  2N23 A;  4XWX A;  1M7R A;  3F0W A;  2P0F A;  3U8Z A;  3ODO A;  1QC6 A;  2DA0 A;  2GJY A;  1BTN A;  4HDO A;  1V88 A;  2H7D A;  1XKE A;  2I5F A;  3ZVR A;  5HE3 A;  2OQB A;  2M14 A;  2R09 A;  4PNK A;  1XOD A;  1UNR A;  2K00 A;  3KY9 A;  1GC6 A;  1V5P A;  1EF1 A;  2NMB A;  5CLL B;  2IFS A;  1WI1 A;  1U27 A;  5CLQ B;  1J19 A;  1ZVR A;  5FI0 A;  2CY5 A;  5D3X A;  1RRP B;  3D8E A;  4ZRK A;  3F5R A;  4Z2M B;  2VRW B;  2I5C A;  3VOQ A;  1W1D A;  2N0Y A;  5DHA B;  2LUL A;  3ML4 A;  1I2H A;  4HAY B;  1FHO A;  2YF0 A;  2EJ8 A;  2Y8G A;  2DHI A;  4HDQ A;  4EMO A;  3KZ1 A;  2P0H A;  3O96 A;  5C79 A;  2RNR B;  3OAN A;  4WJ7 A;  3X23 A;  1X11 A;  1Z87 A;  2D2Q A;  4A6F A;  5LON B;  2FJL A;  1OY2 A;  2EMS A;  3MPX A;  2DLW A;  3N7C A;  1WJ1 A;  1XCG A;  4D0N B;  1NTV A;  5DI9 B;  2PZ1 A;  4ZRI A;  1U5E A;  3GYP A;  3TW1 A;  4CYE A;  2D9Z A;  1W1H A;  3QBV B;  3IVF A;  1PLS A;  4DX9 0;  1UPR A;  1FB8 A;  2KGX B;  1XD4 A;  1U5G A;  3RCP A;  5J3T A;  1TJ6 A;  3SYX A;  1EGX A;  5J3Y A;  3PVW A;  5D3Y A;  4DBB A;  1RJ2 A;  3SUZ A;  4DX8 A;  1OQN A;  3P6A A;  4GPT B;  1UNQ A;  3ZDT A;  2ZPY A;  4A5K A;  4DXA B;  4B6H A;  4CHM A;  1DDM A;  3PP2 A;  1U2B A;  3AJ4 A;  2ELA A;  4EKU A;  1ZC4 B;  1MK7 B;  1W1G A;  4GMV A;  2D9Y A;  4PQ0 A;  3DXE A;  2YS3 A;  3HQC A;  3TFM A;  2GCJ A;  2DHK A;  4WVF B;  3P7Z A;  2YSZ A;  1UEF A;  2R0D A;  4P7I A;  3QIJ A;  1K5D B;  1H10 A;  4A6H A;  3SO6 A;  2GCL A;  3WA0 A;  4HAW B;  1U5F A;  1TXD A;  1B55 A;  2H7E A;  5J3Q A;  2X18 A;  1PMS A;  1SHC A;  2E2X A;  3T06 A;  4F7U P;  4YON A;  3CXB B;  2HE7 A;  1PFJ A;  1ZC3 B;  3SV1 A;  4HB2 B;  2NZ8 B;  3ULC A;  4HAT B;  1KI1 B;  4BBK A;  2LOX A;  1Q67 A;  1P5T A;  1DYN A;  1ISN A;  4EJN A;  2I1J A;  3PZD A;  2DKQ A;  5C16 A;  2RVB B;  1MAI A;  4TKN A;  1V61 A;  2Y7B A;  4KAX B;  2QKM A;  4HB3 B;  2V76 A;  2D10 A;  2UZR A;  2MWN B;  5DHF B;  2LOZ A;  3PG7 A;  2M38 A;  2W2X D;  3FSS A;  4MY6 A;  3WYF B;  3D8F A;  4F7G A;  5JHG A;  1Y19 B;  1WGQ A;  1MPH A;  2P0D A;  4YL8 A;  4HB0 B;  1SGH A;  1KZG A;  2L2I A;  1WVH A;  3HW2 B;  3ODX A;  3AU4 A;  1XX0 A;  4K2P A;  5DIF B;  3UZT A;  1V89 A;  1NU2 A;  2KUP A;  2DYQ A;  5EFX A;  2Y8F A;  2IYB A;  3KRW A;  1X1G A;  2J59 M;  2EC1 A;  2P8V A;  2D4Q A;  1I7A A;  1NI2 A;  2MFQ A;  5L81 A;  4L6E A;  5C5B A;  3PVL A;  4HB4 B;  3FEH A;  1WGU A;  1FGY A;  4IOY X;  1Y5O A;  2GS0 A;  4NSW A;  4HAU B;  4HHV A;  1DBH A;  1EVH A;  2ROZ B;  3DXD A;  2YT0 A;  4KHB B;  3KRX A;  4IFS A;  3PVU A;  2QKL A;  3BJI A;  2D9W A;  2ROV A;  2W2X C;  1MKE A;  4A6F B;  3A8Q A;  1FHX A;  1X86 A;  3TVV A;  1U5D A;  1H4R A;  1K5G B;  4HAX B;  5KQ4 A;  4K81 A;  1GG3 A;  5DH9 B;  2CY4 A;  5HE0 A;  2COC A;  2COD A;  3ULB A;  5JP4 A;  2YVC A;  3CIK A;  2D9X A;  2Z0Q A;  2DYN A;  2COA A;  4KVG B;  4C0A A;  3ODW A;  2DX5 A;  1OMW A;  5FI1 A;  5HE2 A;  3KSY A;  1IRS A;  4HAZ B;  3FM8 C;  2K2J A;  2YRY A;  3PSC A;  4GXB A;  1E5W A;  3GYO A;  2HTH B;  4GN1 A;  4TYZ A;  2EMT A;  4WSF A;  4NY0 A;  2RGN B;  2COF A;  2W2W A;  3NSU A;  2K2U A;  2XQN M;  5GOW B;  1X1F A;  1EAZ A;  2LYD A;  3G9W A;  3MDB C;  1P3R A;  1MK9 B;  2KCJ A;  1MIX A;  1BAK A;  1TQZ A;  4CHJ A;  5D27 A;  2RSG A;  2D11 A;  1P6S A;  3V5W A;  5D3W A;  2DFK A;  1WG7 A;  1M7E A;  5HE1 A;  2MKR A;  4K2O A;  2Q13 A;  3AU5 A;  1QQG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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