The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
172
|
sequence length |
573
|
structure length |
481
|
Chain Sequence |
KSMNVRVTTMDAELEFAIQQTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGDLTWIKLYKKVMQQDVKKENPLQFKFRAKFYPEDVADELIQEITLKLFYLQVKNAILSDEIYCPPETSVLLASYAVQARHGDHNPAVHGPGFLANDRLLPQRVTDQHKMSREEWEQSITNWWQEHRGMLREDAMMEYLKIAQDLEMYGVNYFEIRNKKNTELWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDRKFIIKPIDKKAPDFVFFAPRVRVNKRILALCMGNHELYMRRRKPDTIDVQQMKAQAREEKLAKQAQREKLQLEIAARERAEKKQQEYQDRLRQMQEEMERSQANLLEAQDMVEDARRKQDEAAAALLAATTPQHHHVAERESGGGDLARGPDDLVDPVADRRTLAERNERLHNQLKALKQDLARSCDETKETAMDKIHRENVRQGRDKYKTLREIRKGNTKRRVDQFENM
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule keywords |
Moesin
|
| publication title |
Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain.
pubmed doi rcsb |
| molecule tags |
Cell adhesion, membrane protein
|
| total genus |
172
|
| structure length |
481
|
| sequence length |
573
|
| ec nomenclature | |
| pdb deposition date | 2006-08-14 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00373 | FERM_M | FERM central domain |
| A | PF00769 | ERM | Ezrin/radixin/moesin family |
| A | PF09379 | FERM_N | FERM N-terminal domain |
| A | PF09380 | FERM_C | FERM C-terminal PH-like domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Up-down Bundle | Single alpha-helices involved in coiled-coils or other helix-helix interfaces | Single alpha-helices involved in coiled-coils or other helix-helix interfaces | ||
| Mainly Alpha | Up-down Bundle | Acyl-CoA Binding Protein | Acyl-CoA Binding Protein | ||
| Mainly Alpha | Alpha Horseshoe | Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat | Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat | ||
| Mainly Beta | Roll | PH-domain like | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | ||
| Alpha Beta | Roll | Ubiquitin-like (UB roll) | Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
