2RRFA

The solution structure of the c-terminal region of zinc finger fyve domain-containing protein 21
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
141
structure length
141
Chain Sequence
GSSGSSGAEFYDKQLKVLLSGATFLVTFGNSEKPETMTCRLSNNQRYLFLDGDSHYEIEIVHISTVQILTEGFPPGGGNARATGMFLQYTVPGTEGVTQLKLTVVEDVTVGRRQAVAWLVAMHKAAKLLYESRDQSGPSSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Unknown function
molecule keywords Zinc finger FYVE domain-containing protein 21
publication title ZF21 protein, a regulator of the disassembly of focal adhesions and cancer metastasis, contains a novel noncanonical pleckstrin homology domain
pubmed doi rcsb
source organism Homo sapiens
total genus 19
structure length 141
sequence length 141
ec nomenclature
pdb deposition date 2010-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16696 ZFYVE21_C Zinc finger FYVE domain-containing protein 21 C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.160 Mainly Beta Roll PH-domain like PH-domain like 2rrfA00
2RRFA
chains in the Genus database with same CATH superfamily
3U7DA 4KVGB 4WSFA 2KUPA 1Z87A 3KRXA 4MT7A 2NBVA 5D3YA 2R2YA 5KQ1A 2J0KA 4HDQA 1DDWA 3AU4A 1U5DA 3GYPA 4KHAA 4P7IA 1XKEA 2DLWA 5J3YA 4CSQA 5FI1A 4Z2NA 1W1HA 2YSZA 3RCPA 5DI9B 2YS3A 2PZ1A 1GG3A 2ROZB 1U5EA 2HE7A 3KSYA 5LONB 5M4YB 2RUKB 2GCJA 3PVUA 1ISNA 2IYBA 3NWAA 2D9XA 3UZTA 1FB8A 1EAZA 2GCLA 5LG4B 2DYQA 1KZGA 4GPTB 1Y19B 3QWMA 3CXBB 1K5DB 2W2XD 4XWXA 1MI1A 1GC7A 4A5KA 5C79A 3HW2B 2DA0A 1KZ7A 2Y8FA 4QJ5B 3F0WA 1NU2A 2RRFA 2DX1A 2COAA 4PQ0A 4A6KA 5J3QA 1I7AA 1WVHA 2Z59A 4QXAB 2KGXB 2GJYA 3QBVB 1DYNA 5JLJB 2D9WA 3PSCA 2YT0A 1ZVRA 2AL6A 2J0MA 3U8ZA 1XX0A 5KCVA 2D4QA 4HAVB 4HSIA 4H8SA 2HTHB 4DBBA 1X86A 2I5FA 3AU5A 2Y7BA 2K8EA 4Y94A 2ELAA 1M7RA 4L6EA 4PNKA 4HATB 5EFXA 2KUQA 1J0WA 1MIZB 2DN6A 2EMSA 4DIXA 4DX8A 3PVWA 4ZRIA 4K17A 1W1GA 1IRSA 1PFJA 4HB4B 5DH9B 1WJ1A 1M7EA 4GNKB 1J19A 5HE2A 4GXBA 4GOUA 3T06A 4CHMA 4DX90 3TCAA 1UPRA 2MKRA 4HHVA 1U2BA 3BINA 2P8VA 3MPXA 1DBHA 1H10A 3A8PA 2DTCA 1Y5OA 3TO1A 2Z0QA 3O96A 2ZPYA 2E2XA 2AEHA 2R0DA 2MWNB 2RNRB 4F7GA 2DX5A 3ZVRA 5I2SA 2CY5A 1AQCA 2D9YA 1DDVA 2ZKMX 3D8DA 3ZDTA 2EC1A 3NWDA 1OQNA 2YVCA 4GZUA 2M14A 2EJ8A 3A98B 1U27A 2YRYA 1BTNA 3SUZA 2CY4A 1U5GA 4EJNA 4Z2MB 2IFSA 1FOEA 1QQGA 3IVFA 2YT2A 1Q67A 2L1CA 2Z0PA 3M1IB 2K49A 2W2WA 2W2XC 1I2HA 2Z0OA 4YL8A 2LOZA 2RVBB 3PZDA 5D3WA 2H7DA 5L81A 3BJIA 5JP4A 3KRWA 1P6SA 4D6WA 2DKPA 2I5CA 4D0NB 2J59M 1ZC4B 2K2JA 3GYOA 2KIGA 1OY2A 1FHXA 4ZRKA 2M38A 1MKEA 4OT1A 1BTKA 1B55A 1T77A 5DHFB 2CODA 4ZRJA 2DHIA 1PLSA 3X23A 4B6HA 4F7UP 5JHGA 2Q13A 3LJUX 4MK0A 5CLLB 1XODA 1P5TA 1MIXA 1SGHA 1V5PA 2FJUB 3TW1A 1TQZA 3OHMB 1WJMA 2K2UA 4IAPA 2R09A 1QC6A 4BBKA 2LULA 4DXAB 2LOXA 5IRSA 4HB2B 1V88A 2KCJA 1W1DA 2ROVA 3DXDA 5D3XA 2MFQA 3FVCA 3NW8A 1OMWA 2DHJA 1V5UA 1V5MA 4YONA 2YS5A 5D3VA 3WYFB 4QJ4B 4A6FB 5HE0A 1H4RA 2D11A 1WG7A 1NTYA 4HAYB 4K2OA 2X18A 2QKMA 2G35A 2LG1A 3DCXA 4CHJA 1XD4A 4HAZB 3HIEA 1E5WA 1FHOA 4EMOA 1FHWA 2DKQA 2UZRA 4IFSA 1NTVA 5C6RA 2V76A 3VOQA 1EGXA 4A6HA 4K2PA 4TKNA 3PVLA 1AWEA 1TJ6A 1KI1B 2D2QA 3P7ZA 5DIFB 3AJ4A 2LKOA 1LW3A 2J0JA 2RLOA 1XCGA 4WJ7A 1MK7B 3DXCA 5FI0A 1GC6A 1V89A 1MPHA 3PP2A 2UZSA 1EF1A 2FJLA 1RJ2A 4KHBB 3P6AA 1X1FA 2D9ZA 3NWFA 1RRPB 4KHBA 5I2MA 1PMSA 2CAYA 4HDOA 5GOWB 1BWNA 3FSSA 3TFMA 2XQNM 2I1JA 2VRWB 3V5WA 5HE1A 3CIKA 2VSZA 2P0HA 4HAXB 3FM8C 3ULBA 1V61A 3SNHA 4F7HA 1UPQA 4C0AA 4KAXB 3N7CA 2P0DA 4WVFB 1TXDA 4GN1A 2OQBA 4EKUA 1ZM0A 3DXEA 3OANA 3TVVA 1XR0B 5C5BB 1U29A 2DHKA 3ODXA 1DROA 4HAWB 3QIJA 3D8FA 3KZ1A 4K81A 4QJ3B 4CYEA 1SHCA 5C5BA 3ULCA 2Z4DA 1ZYIA 4HB3B 3MDBC 1EVHA 3WA0A 5C16A 3F5RA 2I1KA 3SYXA 2D9VA 2KIEA 3HSAA 2UVMA 4GMVA 1FGYA 2DYNA 5J3TA 3D8EA 1P3RA 3HK0A 3SV1A 3FEHA 2QKLA 4NY0A 3PEGA 2Z13A 2N0YA 1UEFA 2OTXA 2RGNB 2LYDA 2N23A 1WI1A 3ML4A 1X05A 2KR0A 3ODWA 3B77A 4GMXB 4MY6A 3G9WA 2NZ8B 2YS1A 1UNQA 1X11A 5DHAB 2ELBA 1WGQA 2H7EA 2Y8GA 2EMTA 3KY9A 4A6FA 3VIAA 1U5FA 2CRFA 4TYZA 4NSWA 5KQ4A 3NSUA 1WGUA 3A58A 4KHOA 5CLQB 2NMBA 4HB0B 1DDMA 3HQCA 4HAUB 1NI2A 2ADZA 3A8QA 2JP2A 2DFKA 3ODOA 2Z14A 4L1RA 1K5GB 2COFA 5JHHA 1LB1A 2RSGA 5LOPB 5HE3A 1N3HA 4OSNA 2MDXA 2BCJA 2GUMA 1MAIA 5D27A 1X1GA 4IOYX 2COCA 1MK9B 1FGZA 2YT1A 2D10A 1FAOA 2YF0A 3SO6A 2K00A 3U12A 1ZSQA 2L2IA 3PG7A 2P0FA 2GS0A 2VKIA 1UNPA 1UNRA 1ZC3B 1BAKA
chains in the Genus database with same CATH topology
4GNKB 4OSNA 5IRSA 2RRFA 2ZKMX 2Z13A 4GOUA 2NBVA 3HIEA 2GUMA 2Z4DA 2R2YA 4PQ0A 5M4YB 1ZYIA 3NWDA 2K8EA 2GCJA 4IOYX 3FVCA 3A58A 3NWAA 2Z59A 2KR0A 3GYPA 2KUQA 3NW8A 2GCLA 4KHBB 4KHOA 4QXAB 4D6WA 5LG4B 4KHAA 4IFSA 5I2SA 3NWFA 4DIXA 4Z2MB 3TO1A 4KHBA 5I2MA 4CSQA 2KIEA 2FJUB 2YT2A 2KIGA 3GYOA 3TW1A 2Z14A 4L1RA 4QJ4B 4Z2NA 3U12A 2K49A 3TVVA 3FSSA 3OHMB 4HSIA 4QJ5B 4QJ3B 4OT1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RRF A; 
#chains in the Genus database with same CATH topology
 3U7D A;  4KVG B;  4WSF A;  2KUP A;  1Z87 A;  3KRX A;  4MT7 A;  2NBV A;  5D3Y A;  2R2Y A;  5KQ1 A;  2J0K A;  4HDQ A;  1DDW A;  3AU4 A;  1U5D A;  3GYP A;  4KHA A;  4P7I A;  1XKE A;  2DLW A;  5J3Y A;  4CSQ A;  5FI1 A;  4Z2N A;  1W1H A;  2YSZ A;  3RCP A;  5DI9 B;  2YS3 A;  2PZ1 A;  1GG3 A;  2ROZ B;  1U5E A;  2HE7 A;  3KSY A;  5LON B;  5M4Y B;  2RUK B;  2GCJ A;  3PVU A;  1ISN A;  2IYB A;  3NWA A;  2D9X A;  3UZT A;  1FB8 A;  1EAZ A;  2GCL A;  5LG4 B;  2DYQ A;  1KZG A;  4GPT B;  1Y19 B;  3QWM A;  3CXB B;  1K5D B;  2W2X D;  4XWX A;  1MI1 A;  1GC7 A;  4A5K A;  5C79 A;  3HW2 B;  2DA0 A;  1KZ7 A;  2Y8F A;  4QJ5 B;  3F0W A;  1NU2 A;  2RRF A;  2DX1 A;  2COA A;  4PQ0 A;  4A6K A;  5J3Q A;  1I7A A;  1WVH A;  2Z59 A;  4QXA B;  2KGX B;  2GJY A;  3QBV B;  1DYN A;  5JLJ B;  2D9W A;  3PSC A;  2YT0 A;  1ZVR A;  2AL6 A;  2J0M A;  3U8Z A;  1XX0 A;  5KCV A;  2D4Q A;  4HAV B;  4HSI A;  4H8S A;  2HTH B;  4DBB A;  1X86 A;  2I5F A;  3AU5 A;  2Y7B A;  2K8E A;  4Y94 A;  2ELA A;  1M7R A;  4L6E A;  4PNK A;  4HAT B;  5EFX A;  2KUQ A;  1J0W A;  1MIZ B;  2DN6 A;  2EMS A;  4DIX A;  4DX8 A;  3PVW A;  4ZRI A;  4K17 A;  1W1G A;  1IRS A;  1PFJ A;  4HB4 B;  5DH9 B;  1WJ1 A;  1M7E A;  4GNK B;  1J19 A;  5HE2 A;  4GXB A;  4GOU A;  3T06 A;  4CHM A;  4DX9 0;  3TCA A;  1UPR A;  2MKR A;  4HHV A;  1U2B A;  3BIN A;  2P8V A;  3MPX A;  1DBH A;  1H10 A;  3A8P A;  2DTC A;  1Y5O A;  3TO1 A;  2Z0Q A;  3O96 A;  2ZPY A;  2E2X A;  2AEH A;  2R0D A;  2MWN B;  2RNR B;  4F7G A;  2DX5 A;  3ZVR A;  5I2S A;  2CY5 A;  1AQC A;  2D9Y A;  1DDV A;  2ZKM X;  3D8D A;  3ZDT A;  2EC1 A;  3NWD A;  1OQN A;  2YVC A;  4GZU A;  2M14 A;  2EJ8 A;  3A98 B;  1U27 A;  2YRY A;  1BTN A;  3SUZ A;  2CY4 A;  1U5G A;  4EJN A;  4Z2M B;  2IFS A;  1FOE A;  1QQG A;  3IVF A;  2YT2 A;  1Q67 A;  2L1C A;  2Z0P A;  3M1I B;  2K49 A;  2W2W A;  2W2X C;  1I2H A;  2Z0O A;  4YL8 A;  2LOZ A;  2RVB B;  3PZD A;  5D3W A;  2H7D A;  5L81 A;  3BJI A;  5JP4 A;  3KRW A;  1P6S A;  4D6W A;  2DKP A;  2I5C A;  4D0N B;  2J59 M;  1ZC4 B;  2K2J A;  3GYO A;  2KIG A;  1OY2 A;  1FHX A;  4ZRK A;  2M38 A;  1MKE A;  4OT1 A;  1BTK A;  1B55 A;  1T77 A;  5DHF B;  2COD A;  4ZRJ A;  2DHI A;  1PLS A;  3X23 A;  4B6H A;  4F7U P;  5JHG A;  2Q13 A;  3LJU X;  4MK0 A;  5CLL B;  1XOD A;  1P5T A;  1MIX A;  1SGH A;  1V5P A;  2FJU B;  3TW1 A;  1TQZ A;  3OHM B;  1WJM A;  2K2U A;  4IAP A;  2R09 A;  1QC6 A;  4BBK A;  2LUL A;  4DXA B;  2LOX A;  5IRS A;  4HB2 B;  1V88 A;  2KCJ A;  1W1D A;  2ROV A;  3DXD A;  5D3X A;  2MFQ A;  3FVC A;  3NW8 A;  1OMW A;  2DHJ A;  1V5U A;  1V5M A;  4YON A;  2YS5 A;  5D3V A;  3WYF B;  4QJ4 B;  4A6F B;  5HE0 A;  1H4R A;  2D11 A;  1WG7 A;  1NTY A;  4HAY B;  4K2O A;  2X18 A;  2QKM A;  2G35 A;  2LG1 A;  3DCX A;  4CHJ A;  1XD4 A;  4HAZ B;  3HIE A;  1E5W A;  1FHO A;  4EMO A;  1FHW A;  2DKQ A;  2UZR A;  4IFS A;  1NTV A;  5C6R A;  2V76 A;  3VOQ A;  1EGX A;  4A6H A;  4K2P A;  4TKN A;  3PVL A;  1AWE A;  1TJ6 A;  1KI1 B;  2D2Q A;  3P7Z A;  5DIF B;  3AJ4 A;  2LKO A;  1LW3 A;  2J0J A;  2RLO A;  1XCG A;  4WJ7 A;  1MK7 B;  3DXC A;  5FI0 A;  1GC6 A;  1V89 A;  1MPH A;  3PP2 A;  2UZS A;  1EF1 A;  2FJL A;  1RJ2 A;  4KHB B;  3P6A A;  1X1F A;  2D9Z A;  3NWF A;  1RRP B;  4KHB A;  5I2M A;  1PMS A;  2CAY A;  4HDO A;  5GOW B;  1BWN A;  3FSS A;  3TFM A;  2XQN M;  2I1J A;  2VRW B;  3V5W A;  5HE1 A;  3CIK A;  2VSZ A;  2P0H A;  4HAX B;  3FM8 C;  3ULB A;  1V61 A;  3SNH A;  4F7H A;  1UPQ A;  4C0A A;  4KAX B;  3N7C A;  2P0D A;  4WVF B;  1TXD A;  4GN1 A;  2OQB A;  4EKU A;  1ZM0 A;  3DXE A;  3OAN A;  3TVV A;  1XR0 B;  5C5B B;  1U29 A;  2DHK A;  3ODX A;  1DRO A;  4HAW B;  3QIJ A;  3D8F A;  3KZ1 A;  4K81 A;  4QJ3 B;  4CYE A;  1SHC A;  5C5B A;  3ULC A;  2Z4D A;  1ZYI A;  4HB3 B;  3MDB C;  1EVH A;  3WA0 A;  5C16 A;  3F5R A;  2I1K A;  3SYX A;  2D9V A;  2KIE A;  3HSA A;  2UVM A;  4GMV A;  1FGY A;  2DYN A;  5J3T A;  3D8E A;  1P3R A;  3HK0 A;  3SV1 A;  3FEH A;  2QKL A;  4NY0 A;  3PEG A;  2Z13 A;  2N0Y A;  1UEF A;  2OTX A;  2RGN B;  2LYD A;  2N23 A;  1WI1 A;  3ML4 A;  1X05 A;  2KR0 A;  3ODW A;  3B77 A;  4GMX B;  4MY6 A;  3G9W A;  2NZ8 B;  2YS1 A;  1UNQ A;  1X11 A;  5DHA B;  2ELB A;  1WGQ A;  2H7E A;  2Y8G A;  2EMT A;  3KY9 A;  4A6F A;  3VIA A;  1U5F A;  2CRF A;  4TYZ A;  4NSW A;  5KQ4 A;  3NSU A;  1WGU A;  3A58 A;  4KHO A;  5CLQ B;  2NMB A;  4HB0 B;  1DDM A;  3HQC A;  4HAU B;  1NI2 A;  2ADZ A;  3A8Q A;  2JP2 A;  2DFK A;  3ODO A;  2Z14 A;  4L1R A;  1K5G B;  2COF A;  5JHH A;  1LB1 A;  2RSG A;  5LOP B;  5HE3 A;  1N3H A;  4OSN A;  2MDX A;  2BCJ A;  2GUM A;  1MAI A;  5D27 A;  1X1G A;  4IOY X;  2COC A;  1MK9 B;  1FGZ A;  2YT1 A;  2D10 A;  1FAO A;  2YF0 A;  3SO6 A;  2K00 A;  3U12 A;  1ZSQ A;  2L2I A;  3PG7 A;  2P0F A;  2GS0 A;  2VKI A;  1UNP A;  1UNR A;  1ZC3 B;  1BAK A; 
#chains in the Genus database with same CATH homology
 4GNK B;  4OSN A;  5IRS A;  2RRF A;  2ZKM X;  2Z13 A;  4GOU A;  2NBV A;  3HIE A;  2GUM A;  2Z4D A;  2R2Y A;  4PQ0 A;  5M4Y B;  1ZYI A;  3NWD A;  2K8E A;  2GCJ A;  4IOY X;  3FVC A;  3A58 A;  3NWA A;  2Z59 A;  2KR0 A;  3GYP A;  2KUQ A;  3NW8 A;  2GCL A;  4KHB B;  4KHO A;  4QXA B;  4D6W A;  5LG4 B;  4KHA A;  4IFS A;  5I2S A;  3NWF A;  4DIX A;  4Z2M B;  3TO1 A;  4KHB A;  5I2M A;  4CSQ A;  2KIE A;  2FJU B;  2YT2 A;  2KIG A;  3GYO A;  3TW1 A;  2Z14 A;  4L1R A;  4QJ4 B;  4Z2N A;  3U12 A;  2K49 A;  3TVV A;  3FSS A;  3OHM B;  4HSI A;  4QJ5 B;  4QJ3 B;  4OT1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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