5D3YA

Crystal structure of the p-rex1 ph domain with inositol-(1,3,4,5)-tetrakisphosphate bound
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
151
structure length
136
Chain Sequence
ALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKSRVSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Lipid binding protein
molecule keywords Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac excha
publication title Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
pubmed doi rcsb
source organism Homo sapiens
total genus 40
structure length 136
sequence length 151
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-08-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 5d3yA00
4CHMA 2YS3A 5C5BA 4DX8A 2QKLA 3U7DA 2IFSA 1UPQA 3ODWA 2E2XA 2RVBB 1QQGA 2YVCA 2DX1A 2P0FA 2DTCA 5FI1A 1ZC3B 2UZSA 3CXBB 1MIZB 4HAWB 4HB3B 1OQNA 5DHFB 4GMXB 2D11A 1WI1A 3KRXA 3G9WA 1P6SA 2M14A 2H7DA 2P0HA 3X23A 4KAXB 1UNRA 4KHOA 4CHJA 1U5FA 2NMBA 2NZ8B 1BTNA 3TW1A 4A6FA 4F7HA 2L2IA 3HK0A 3HQCA 4IFSA 4PQ0A 3SO6A 1DROA 4IAPA 1P5TA 3U8ZA 3D8DA 4HB0B 3ML4A 1WG7A 2YSZA 3AU4A 2D9WA 3O96A 5HE3A 2ROVA 2VRWB 1FHXA 2XQNM 1Y19B 1Q67A 1UNQA 1WGQA 3TO1A 4HB4B 2R09A 1FAOA 2J0KA 5KCVA 3SNHA 4D0NB 2LOXA 3TCAA 4K81A 4A6FB 3SYXA 2LYDA 1XD4A 4EJNA 4HDOA 3TVVA 2D10A 3QWMA 2Y8FA 4XWXA 1BTKA 1Y5OA 4WJ7A 1EVHA 2RGNB 4HAXB 2QKMA 1EAZA 3A8QA 3QBVB 2CY5A 2V76A 4ZRJA 1U2BA 5C16A 1EF1A 2CODA 3SV1A 4Y94A 3DXDA 1TQZA 2G35A 1FGYA 2DKPA 2RUKB 2D9ZA 1XCGA 4DBBA 4KHAA 2N0YA 3TFMA 4HAYB 2HTHB 3GYPA 4NSWA 2ELBA 4KHBB 2L1CA 3FEHA 1SHCA 3M1IB 4K2OA 4Z2MB 3MPXA 3GYOA 3UZTA 2W2XC 3VOQA 5D3WA 5DH9B 2LULA 3P6AA 3DXCA 2I1JA 5LONB 1E5WA 1RJ2A 2LG1A 1NTYA 1X05A 3D8FA 1X1GA 1B55A 5CLQB 1W1GA 3P7ZA 1K5GB 2PZ1A 4GN1A 2D9YA 1J19A 2COFA 1XODA 3PVLA 4KVGB 2GS0A 3KSYA 2COAA 5KQ1A 1U5DA 3AJ4A 4DXAB 1UNPA 2K2JA 3KZ1A 3F0WA 3QIJA 4MY6A 1U29A 2KCJA 3D8EA 5D3XA 1V5UA 1MPHA 1MK7B 4P7IA 1WVHA 1ZVRA 5C5BB 2YS1A 1V5PA 2P8VA 1UPRA 5J3TA 2COCA 1V89A 2FJLA 1Z87A 1AQCA 3WYFB 5JHHA 5GOWB 1BAKA 4YL8A 2D2QA 4F7UP 2N23A 2Q13A 2VKIA 3OANA 5JLJB 1IRSA 2RSGA 1P3RA 3MDBC 4F7GA 1X11A 1V88A 5CLLB 2MKRA 5LOPB 4WSFA 4WVFB 1FHWA 1U5GA 4ZRIA 4Z2NA 1FOEA 4A6HA 1GC6A 2W2WA 1MAIA 4A6KA 3PEGA 2CAYA 1NTVA 4GXBA 2YT0A 4HHVA 5FI0A 1PMSA 2DKQA 2Y7BA 1GC7A 2DLWA 1DYNA 1QC6A 2AEHA 4HAZB 2Z0PA 2GCJA 2KUPA 4EKUA 1NU2A 1ZM0A 1KZGA 5D3YA 1PLSA 2CY4A 1WGUA 2AL6A 1NI2A 5JP4A 2Z0OA 3V5WA 3PG7A 5JHGA 1V5MA 1MK9B 1I2HA 4C0AA 3FSSA 2K00A 3ZDTA 4GZUA 4BBKA 2DN6A 1X86A 2EC1A 3BINA 3F5RA 1W1HA 4K2PA 2YT1A 2JP2A 1J0WA 2YRYA 2GJYA 4HAUB 4A5KA 2ROZB 2YS5A 5J3YA 1DDVA 4MT7A 2CRFA 2LOZA 1MIXA 3ODOA 2W2XD 1LB1A 1XX0A 2M38A 3KY9A 4ZRKA 1H10A 4B6HA 4TKNA 5DI9B 4YONA 2D9XA 4NY0A 1U5EA 1W1DA 1WJ1A 2J0JA 3A98B 3AU5A 2VSZA 1OMWA 3N7CA 1XR0B 4MK0A 2I1KA 1ISNA 3HW2B 5C6RA 2Z0QA 2DA0A 1DDMA 1DBHA 2GCLA 1TXDA 2HE7A 1AWEA 3PSCA 3LJUX 1BWNA 2KGXB 5KQ4A 2UZRA 2DFKA 1ZC4B 2K2UA 3NSUA 4GMVA 2ELAA 3IVFA 2MFQA 2UVMA 1FGZA 5HE0A 2P0DA 2OQBA 2IYBA 3RCPA 2D4QA 1M7EA 2DYNA 1RRPB 1H4RA 2MWNB 4HATB 3ODXA 3PVUA 2RNRB 2EJ8A 3T06A 3PP2A 4TYZA 3SUZA 1N3HA 5EFXA 5DIFB 1K5DB 1FHOA 1KI1B 1KZ7A 4HDQA 3ZVRA 2BCJA 3VIAA 5D3VA 1UEFA 2I5CA 1DDWA 5L81A 1FB8A 4H8SA 3BJIA 5HE1A 1ZSQA 2LKOA 2EMSA 2MDXA 2RLOA 3WA0A 1PFJA 2H7EA 5D27A 4GPTB 3DXEA 5C79A 3A8PA 3ULCA 1SGHA 4K17A 2Y8GA 1GG3A 2ZPYA 1MKEA 4PNKA 1LW3A 2X18A 3FM8C 2D9VA 4L6EA 4HB2B 3ULBA 2J59M 4CYEA 5DHAB 2OTXA 3PVWA 2ADZA 1XKEA 2YF0A 3KRWA 2EMTA 2DX5A 3PZDA 1M7RA 3CIKA 2DYQA 5HE2A 1V61A 2R0DA 4HAVB 1X1FA 4IOYX 2DHKA 1I7AA 4DX90 1OY2A 2J0MA 4EMOA 1EGXA 1WJMA 2DHIA 5J3QA 2DHJA 2I5FA 1TJ6A 1U27A
chains in the Genus database with same CATH superfamily
4CHMA 2YS3A 5C5BA 4DX8A 2QKLA 3U7DA 2IFSA 1UPQA 3ODWA 2E2XA 2RVBB 1QQGA 2YVCA 2DX1A 2P0FA 2DTCA 5FI1A 1ZC3B 2UZSA 3CXBB 1MIZB 4OT1A 4HAWB 4HB3B 1OQNA 5DHFB 4GMXB 2D11A 1WI1A 3KRXA 3G9WA 1P6SA 2M14A 2Z14A 2H7DA 2P0HA 3X23A 4KAXB 1UNRA 4KHOA 4CHJA 1U5FA 2NMBA 4HSIA 2NZ8B 1BTNA 3TW1A 4A6FA 4F7HA 2L2IA 3HK0A 3HQCA 4DIXA 4IFSA 4PQ0A 3SO6A 1DROA 4IAPA 1P5TA 3U8ZA 3D8DA 4HB0B 3ML4A 1WG7A 2YSZA 3AU4A 2Z13A 2D9WA 3O96A 5HE3A 2ROVA 2VRWB 1FHXA 2XQNM 1Y19B 1Q67A 1UNQA 1WGQA 3TO1A 4HB4B 2R09A 1FAOA 2J0KA 5KCVA 3SNHA 4D0NB 2LOXA 3TCAA 4K81A 4A6FB 3SYXA 2LYDA 1XD4A 4EJNA 4HDOA 1ZYIA 3TVVA 3OHMB 5IRSA 2D10A 3QWMA 2Y8FA 4XWXA 1BTKA 1Y5OA 4WJ7A 1EVHA 2RGNB 4HAXB 4QXAB 2QKMA 1EAZA 3A8QA 1MI1A 2CY5A 2V76A 3QBVB 4ZRJA 1U2BA 5C16A 1EF1A 2CODA 3SV1A 2Z4DA 4Y94A 3DXDA 1TQZA 2G35A 1FGYA 2DKPA 2RUKB 2D9ZA 1XCGA 4DBBA 4KHAA 2N0YA 1T77A 3TFMA 4HAYB 2HTHB 3GYPA 4NSWA 2ELBA 4KHBB 2L1CA 3FEHA 1SHCA 3FVCA 3M1IB 4K2OA 4Z2MB 3MPXA 3GYOA 3UZTA 2W2XC 3VOQA 5D3WA 5DH9B 2LULA 3P6AA 3DXCA 2Z59A 2I1JA 5LONB 1E5WA 1RJ2A 2LG1A 1NTYA 1X05A 3D8FA 1X1GA 1B55A 5CLQB 1W1GA 3P7ZA 1K5GB 2PZ1A 4GN1A 2D9YA 1J19A 2COFA 1XODA 3PVLA 4KVGB 2GS0A 3KSYA 2COAA 5KQ1A 1U5DA 3AJ4A 4DXAB 1UNPA 3A58A 2K2JA 3KZ1A 3F0WA 3HSAA 3QIJA 2YT2A 4MY6A 1U29A 2KCJA 3D8EA 5D3XA 3HIEA 1V5UA 1MPHA 1MK7B 4P7IA 1WVHA 1ZVRA 5C5BB 2YS1A 1V5PA 2P8VA 1UPRA 5J3TA 2COCA 1V89A 2FJLA 1Z87A 1AQCA 3WYFB 5JHHA 5GOWB 1BAKA 4YL8A 2D2QA 4F7UP 2N23A 2Q13A 2VKIA 3OANA 5JLJB 1IRSA 2RSGA 1P3RA 3MDBC 2KR0A 1X11A 4F7GA 1V88A 5CLLB 2MKRA 5LOPB 4WSFA 4WVFB 2R2YA 1FHWA 1U5GA 4ZRIA 4Z2NA 1FOEA 4A6HA 1GC6A 2W2WA 1MAIA 4A6KA 3PEGA 2CAYA 1NTVA 4GXBA 5I2MA 2YT0A 4HHVA 5FI0A 1PMSA 4QJ4B 2DKQA 2Y7BA 1GC7A 3DCXA 2DLWA 1DYNA 1QC6A 2AEHA 4HAZB 2Z0PA 2GCJA 2KUPA 4EKUA 1NU2A 1ZM0A 1KZGA 5D3YA 1PLSA 2KUQA 2CY4A 1WGUA 2AL6A 1NI2A 5JP4A 2Z0OA 3V5WA 3PG7A 5JHGA 1V5MA 1MK9B 1I2HA 4C0AA 3FSSA 2K00A 3ZDTA 4GZUA 4BBKA 2DN6A 1X86A 2EC1A 3BINA 3F5RA 3U12A 1W1HA 4K2PA 2YT1A 2JP2A 1J0WA 2YRYA 2GJYA 4HAUB 4A5KA 2ROZB 2YS5A 5J3YA 1DDVA 4MT7A 2CRFA 2LOZA 2RRFA 1MIXA 2K49A 3ODOA 2W2XD 1LB1A 1XX0A 2M38A 3KY9A 2K8EA 4ZRKA 1H10A 4B6HA 4TKNA 5DI9B 4YONA 2D9XA 4NY0A 1U5EA 1W1DA 1WJ1A 2J0JA 3A98B 3AU5A 2VSZA 1OMWA 3N7CA 1XR0B 4MK0A 2I1KA 1ISNA 3HW2B 5C6RA 2Z0QA 2DA0A 4D6WA 1DDMA 3B77A 1DBHA 2GCLA 1TXDA 2HE7A 1AWEA 3PSCA 3LJUX 1BWNA 2KGXB 2KIGA 5KQ4A 2UZRA 2DFKA 1ZC4B 2K2UA 3NSUA 4GMVA 2ELAA 2MFQA 3IVFA 2UVMA 1FGZA 5HE0A 2P0DA 2OQBA 2IYBA 3NWAA 3RCPA 2D4QA 1M7EA 2DYNA 1RRPB 1H4RA 2MWNB 4HATB 3ODXA 3PVUA 2RNRB 4OSNA 2EJ8A 3T06A 3PP2A 4TYZA 3SUZA 1N3HA 5EFXA 5DIFB 1K5DB 4QJ5B 1FHOA 1KI1B 1KZ7A 4HDQA 3ZVRA 2BCJA 3VIAA 5D3VA 1UEFA 2I5CA 1DDWA 5L81A 1FB8A 4H8SA 3BJIA 5HE1A 1ZSQA 2LKOA 2EMSA 2GUMA 2MDXA 2RLOA 3WA0A 4CSQA 1PFJA 2H7EA 5D27A 4GPTB 3DXEA 3NW8A 5C79A 3A8PA 3ULCA 1SGHA 4K17A 2Y8GA 4KHBA 4GNKB 1GG3A 2ZPYA 1MKEA 4PNKA 2KIEA 1LW3A 2X18A 3FM8C 2FJUB 2D9VA 4L6EA 4HB2B 3ULBA 4QJ3B 2J59M 4L1RA 4CYEA 5DHAB 5M4YB 2OTXA 3PVWA 2ADZA 1XKEA 2YF0A 3KRWA 2EMTA 2DX5A 3PZDA 1M7RA 2ZKMX 3CIKA 3NWFA 2DYQA 5HE2A 1V61A 2NBVA 2R0DA 4HAVB 1X1FA 4IOYX 2DHKA 1I7AA 4DX90 1OY2A 2J0MA 4EMOA 5LG4B 1EGXA 1WJMA 2DHIA 3NWDA 5I2SA 5J3QA 4GOUA 2DHJA 2I5FA 1TJ6A 1U27A
chains in the Genus database with same CATH topology
4CHMA 2YS3A 5C5BA 4DX8A 2QKLA 3U7DA 2IFSA 1UPQA 3ODWA 2E2XA 2RVBB 1QQGA 2YVCA 2DX1A 2P0FA 2DTCA 5FI1A 1ZC3B 2UZSA 3CXBB 1MIZB 4HAWB 4HB3B 1OQNA 5DHFB 4GMXB 2D11A 1WI1A 3KRXA 3G9WA 1P6SA 2M14A 2H7DA 2P0HA 3X23A 4KAXB 1UNRA 4KHOA 4CHJA 1U5FA 2NMBA 2NZ8B 1BTNA 3TW1A 4A6FA 4F7HA 2L2IA 3HK0A 3HQCA 4IFSA 4PQ0A 3SO6A 1DROA 4IAPA 1P5TA 3U8ZA 3D8DA 4HB0B 3ML4A 1WG7A 2YSZA 3AU4A 2D9WA 3O96A 5HE3A 2ROVA 2VRWB 1FHXA 2XQNM 1Y19B 1Q67A 1UNQA 1WGQA 3TO1A 4HB4B 2R09A 1FAOA 2J0KA 5KCVA 3SNHA 4D0NB 2LOXA 3TCAA 4K81A 4A6FB 3SYXA 2LYDA 1XD4A 4EJNA 4HDOA 3TVVA 2D10A 3QWMA 2Y8FA 4XWXA 1BTKA 1Y5OA 4WJ7A 1EVHA 2RGNB 4HAXB 2QKMA 1EAZA 3A8QA 3QBVB 2CY5A 2V76A 4ZRJA 1U2BA 5C16A 1EF1A 2CODA 3SV1A 4Y94A 3DXDA 1TQZA 2G35A 1FGYA 2DKPA 2RUKB 2D9ZA 1XCGA 4DBBA 4KHAA 2N0YA 3TFMA 4HAYB 2HTHB 3GYPA 4NSWA 2ELBA 4KHBB 2L1CA 3FEHA 1SHCA 3M1IB 4K2OA 4Z2MB 3MPXA 3GYOA 3UZTA 2W2XC 3VOQA 5D3WA 5DH9B 2LULA 3P6AA 3DXCA 2I1JA 5LONB 1E5WA 1RJ2A 2LG1A 1NTYA 1X05A 3D8FA 1X1GA 1B55A 5CLQB 1W1GA 3P7ZA 1K5GB 2PZ1A 4GN1A 2D9YA 1J19A 2COFA 1XODA 3PVLA 4KVGB 2GS0A 3KSYA 2COAA 5KQ1A 1U5DA 3AJ4A 4DXAB 1UNPA 2K2JA 3KZ1A 3F0WA 3QIJA 4MY6A 1U29A 2KCJA 3D8EA 5D3XA 1V5UA 1MPHA 1MK7B 4P7IA 1WVHA 1ZVRA 5C5BB 2YS1A 1V5PA 2P8VA 1UPRA 5J3TA 2COCA 1V89A 2FJLA 1Z87A 1AQCA 3WYFB 5JHHA 5GOWB 1BAKA 4YL8A 2D2QA 4F7UP 2N23A 2Q13A 2VKIA 3OANA 5JLJB 1IRSA 2RSGA 1P3RA 3MDBC 4F7GA 1X11A 1V88A 5CLLB 2MKRA 5LOPB 4WSFA 4WVFB 1FHWA 1U5GA 4ZRIA 4Z2NA 1FOEA 4A6HA 1GC6A 2W2WA 1MAIA 4A6KA 3PEGA 2CAYA 1NTVA 4GXBA 2YT0A 4HHVA 5FI0A 1PMSA 2DKQA 2Y7BA 1GC7A 2DLWA 1DYNA 1QC6A 2AEHA 4HAZB 2Z0PA 2GCJA 2KUPA 4EKUA 1NU2A 1ZM0A 1KZGA 5D3YA 1PLSA 2CY4A 1WGUA 2AL6A 1NI2A 5JP4A 2Z0OA 3V5WA 3PG7A 5JHGA 1V5MA 1MK9B 1I2HA 4C0AA 3FSSA 2K00A 3ZDTA 4GZUA 4BBKA 2DN6A 1X86A 2EC1A 3BINA 3F5RA 1W1HA 4K2PA 2YT1A 2JP2A 1J0WA 2YRYA 2GJYA 4HAUB 4A5KA 2ROZB 2YS5A 5J3YA 1DDVA 4MT7A 2CRFA 2LOZA 1MIXA 3ODOA 2W2XD 1LB1A 1XX0A 2M38A 3KY9A 4ZRKA 1H10A 4B6HA 4TKNA 5DI9B 4YONA 2D9XA 4NY0A 1U5EA 1W1DA 1WJ1A 2J0JA 3A98B 3AU5A 2VSZA 1OMWA 3N7CA 1XR0B 4MK0A 2I1KA 1ISNA 3HW2B 5C6RA 2Z0QA 2DA0A 1DDMA 1DBHA 2GCLA 1TXDA 2HE7A 1AWEA 3PSCA 3LJUX 1BWNA 2KGXB 5KQ4A 2UZRA 2DFKA 1ZC4B 2K2UA 3NSUA 4GMVA 2ELAA 3IVFA 2MFQA 2UVMA 1FGZA 5HE0A 2P0DA 2OQBA 2IYBA 3RCPA 2D4QA 1M7EA 2DYNA 1RRPB 1H4RA 2MWNB 4HATB 3ODXA 3PVUA 2RNRB 2EJ8A 3T06A 3PP2A 4TYZA 3SUZA 1N3HA 5EFXA 5DIFB 1K5DB 1FHOA 1KI1B 1KZ7A 4HDQA 3ZVRA 2BCJA 3VIAA 5D3VA 1UEFA 2I5CA 1DDWA 5L81A 1FB8A 4H8SA 3BJIA 5HE1A 1ZSQA 2LKOA 2EMSA 2MDXA 2RLOA 3WA0A 1PFJA 2H7EA 5D27A 4GPTB 3DXEA 5C79A 3A8PA 3ULCA 1SGHA 4K17A 2Y8GA 1GG3A 2ZPYA 1MKEA 4PNKA 1LW3A 2X18A 3FM8C 2D9VA 4L6EA 4HB2B 3ULBA 2J59M 4CYEA 5DHAB 2OTXA 3PVWA 2ADZA 1XKEA 2YF0A 3KRWA 2EMTA 2DX5A 3PZDA 1M7RA 3CIKA 2DYQA 5HE2A 1V61A 2R0DA 4HAVB 1X1FA 4IOYX 2DHKA 1I7AA 4DX90 1OY2A 2J0MA 4EMOA 1EGXA 1WJMA 2DHIA 5J3QA 2DHJA 2I5FA 1TJ6A 1U27A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CHM A;  2YS3 A;  5C5B A;  4DX8 A;  2QKL A;  3U7D A;  2IFS A;  1UPQ A;  3ODW A;  2E2X A;  2RVB B;  1QQG A;  2YVC A;  2DX1 A;  2P0F A;  2DTC A;  5FI1 A;  1ZC3 B;  2UZS A;  3CXB B;  1MIZ B;  4HAW B;  4HB3 B;  1OQN A;  5DHF B;  4GMX B;  2D11 A;  1WI1 A;  3KRX A;  3G9W A;  1P6S A;  2M14 A;  2H7D A;  2P0H A;  3X23 A;  4KAX B;  1UNR A;  4KHO A;  4CHJ A;  1U5F A;  2NMB A;  2NZ8 B;  1BTN A;  3TW1 A;  4A6F A;  4F7H A;  2L2I A;  3HK0 A;  3HQC A;  4IFS A;  4PQ0 A;  3SO6 A;  1DRO A;  4IAP A;  1P5T A;  3U8Z A;  3D8D A;  4HB0 B;  3ML4 A;  1WG7 A;  2YSZ A;  3AU4 A;  2D9W A;  3O96 A;  5HE3 A;  2ROV A;  2VRW B;  1FHX A;  2XQN M;  1Y19 B;  1Q67 A;  1UNQ A;  1WGQ A;  3TO1 A;  4HB4 B;  2R09 A;  1FAO A;  2J0K A;  5KCV A;  3SNH A;  4D0N B;  2LOX A;  3TCA A;  4K81 A;  4A6F B;  3SYX A;  2LYD A;  1XD4 A;  4EJN A;  4HDO A;  3TVV A;  2D10 A;  3QWM A;  2Y8F A;  4XWX A;  1BTK A;  1Y5O A;  4WJ7 A;  1EVH A;  2RGN B;  4HAX B;  2QKM A;  1EAZ A;  3A8Q A;  3QBV B;  2CY5 A;  2V76 A;  4ZRJ A;  1U2B A;  5C16 A;  1EF1 A;  2COD A;  3SV1 A;  4Y94 A;  3DXD A;  1TQZ A;  2G35 A;  1FGY A;  2DKP A;  2RUK B;  2D9Z A;  1XCG A;  4DBB A;  4KHA A;  2N0Y A;  3TFM A;  4HAY B;  2HTH B;  3GYP A;  4NSW A;  2ELB A;  4KHB B;  2L1C A;  3FEH A;  1SHC A;  3M1I B;  4K2O A;  4Z2M B;  3MPX A;  3GYO A;  3UZT A;  2W2X C;  3VOQ A;  5D3W A;  5DH9 B;  2LUL A;  3P6A A;  3DXC A;  2I1J A;  5LON B;  1E5W A;  1RJ2 A;  2LG1 A;  1NTY A;  1X05 A;  3D8F A;  1X1G A;  1B55 A;  5CLQ B;  1W1G A;  3P7Z A;  1K5G B;  2PZ1 A;  4GN1 A;  2D9Y A;  1J19 A;  2COF A;  1XOD A;  3PVL A;  4KVG B;  2GS0 A;  3KSY A;  2COA A;  5KQ1 A;  1U5D A;  3AJ4 A;  4DXA B;  1UNP A;  2K2J A;  3KZ1 A;  3F0W A;  3QIJ A;  4MY6 A;  1U29 A;  2KCJ A;  3D8E A;  5D3X A;  1V5U A;  1MPH A;  1MK7 B;  4P7I A;  1WVH A;  1ZVR A;  5C5B B;  2YS1 A;  1V5P A;  2P8V A;  1UPR A;  5J3T A;  2COC A;  1V89 A;  2FJL A;  1Z87 A;  1AQC A;  3WYF B;  5JHH A;  5GOW B;  1BAK A;  4YL8 A;  2D2Q A;  4F7U P;  2N23 A;  2Q13 A;  2VKI A;  3OAN A;  5JLJ B;  1IRS A;  2RSG A;  1P3R A;  3MDB C;  4F7G A;  1X11 A;  1V88 A;  5CLL B;  2MKR A;  5LOP B;  4WSF A;  4WVF B;  1FHW A;  1U5G A;  4ZRI A;  4Z2N A;  1FOE A;  4A6H A;  1GC6 A;  2W2W A;  1MAI A;  4A6K A;  3PEG A;  2CAY A;  1NTV A;  4GXB A;  2YT0 A;  4HHV A;  5FI0 A;  1PMS A;  2DKQ A;  2Y7B A;  1GC7 A;  2DLW A;  1DYN A;  1QC6 A;  2AEH A;  4HAZ B;  2Z0P A;  2GCJ A;  2KUP A;  4EKU A;  1NU2 A;  1ZM0 A;  1KZG A;  5D3Y A;  1PLS A;  2CY4 A;  1WGU A;  2AL6 A;  1NI2 A;  5JP4 A;  2Z0O A;  3V5W A;  3PG7 A;  5JHG A;  1V5M A;  1MK9 B;  1I2H A;  4C0A A;  3FSS A;  2K00 A;  3ZDT A;  4GZU A;  4BBK A;  2DN6 A;  1X86 A;  2EC1 A;  3BIN A;  3F5R A;  1W1H A;  4K2P A;  2YT1 A;  2JP2 A;  1J0W A;  2YRY A;  2GJY A;  4HAU B;  4A5K A;  2ROZ B;  2YS5 A;  5J3Y A;  1DDV A;  4MT7 A;  2CRF A;  2LOZ A;  1MIX A;  3ODO A;  2W2X D;  1LB1 A;  1XX0 A;  2M38 A;  3KY9 A;  4ZRK A;  1H10 A;  4B6H A;  4TKN A;  5DI9 B;  4YON A;  2D9X A;  4NY0 A;  1U5E A;  1W1D A;  1WJ1 A;  2J0J A;  3A98 B;  3AU5 A;  2VSZ A;  1OMW A;  3N7C A;  1XR0 B;  4MK0 A;  2I1K A;  1ISN A;  3HW2 B;  5C6R A;  2Z0Q A;  2DA0 A;  1DDM A;  1DBH A;  2GCL A;  1TXD A;  2HE7 A;  1AWE A;  3PSC A;  3LJU X;  1BWN A;  2KGX B;  5KQ4 A;  2UZR A;  2DFK A;  1ZC4 B;  2K2U A;  3NSU A;  4GMV A;  2ELA A;  3IVF A;  2MFQ A;  2UVM A;  1FGZ A;  5HE0 A;  2P0D A;  2OQB A;  2IYB A;  3RCP A;  2D4Q A;  1M7E A;  2DYN A;  1RRP B;  1H4R A;  2MWN B;  4HAT B;  3ODX A;  3PVU A;  2RNR B;  2EJ8 A;  3T06 A;  3PP2 A;  4TYZ A;  3SUZ A;  1N3H A;  5EFX A;  5DIF B;  1K5D B;  1FHO A;  1KI1 B;  1KZ7 A;  4HDQ A;  3ZVR A;  2BCJ A;  3VIA A;  5D3V A;  1UEF A;  2I5C A;  1DDW A;  5L81 A;  1FB8 A;  4H8S A;  3BJI A;  5HE1 A;  1ZSQ A;  2LKO A;  2EMS A;  2MDX A;  2RLO A;  3WA0 A;  1PFJ A;  2H7E A;  5D27 A;  4GPT B;  3DXE A;  5C79 A;  3A8P A;  3ULC A;  1SGH A;  4K17 A;  2Y8G A;  1GG3 A;  2ZPY A;  1MKE A;  4PNK A;  1LW3 A;  2X18 A;  3FM8 C;  2D9V A;  4L6E A;  4HB2 B;  3ULB A;  2J59 M;  4CYE A;  5DHA B;  2OTX A;  3PVW A;  2ADZ A;  1XKE A;  2YF0 A;  3KRW A;  2EMT A;  2DX5 A;  3PZD A;  1M7R A;  3CIK A;  2DYQ A;  5HE2 A;  1V61 A;  2R0D A;  4HAV B;  1X1F A;  4IOY X;  2DHK A;  1I7A A;  4DX9 0;  1OY2 A;  2J0M A;  4EMO A;  1EGX A;  1WJM A;  2DHI A;  5J3Q A;  2DHJ A;  2I5F A;  1TJ6 A;  1U27 A; 
#chains in the Genus database with same CATH topology
 4CHM A;  2YS3 A;  5C5B A;  4DX8 A;  2QKL A;  3U7D A;  2IFS A;  1UPQ A;  3ODW A;  2E2X A;  2RVB B;  1QQG A;  2YVC A;  2DX1 A;  2P0F A;  2DTC A;  5FI1 A;  1ZC3 B;  2UZS A;  3CXB B;  1MIZ B;  4OT1 A;  4HAW B;  4HB3 B;  1OQN A;  5DHF B;  4GMX B;  2D11 A;  1WI1 A;  3KRX A;  3G9W A;  1P6S A;  2M14 A;  2Z14 A;  2H7D A;  2P0H A;  3X23 A;  4KAX B;  1UNR A;  4KHO A;  4CHJ A;  1U5F A;  2NMB A;  4HSI A;  2NZ8 B;  1BTN A;  3TW1 A;  4A6F A;  4F7H A;  2L2I A;  3HK0 A;  3HQC A;  4DIX A;  4IFS A;  4PQ0 A;  3SO6 A;  1DRO A;  4IAP A;  1P5T A;  3U8Z A;  3D8D A;  4HB0 B;  3ML4 A;  1WG7 A;  2YSZ A;  3AU4 A;  2Z13 A;  2D9W A;  3O96 A;  5HE3 A;  2ROV A;  2VRW B;  1FHX A;  2XQN M;  1Y19 B;  1Q67 A;  1UNQ A;  1WGQ A;  3TO1 A;  4HB4 B;  2R09 A;  1FAO A;  2J0K A;  5KCV A;  3SNH A;  4D0N B;  2LOX A;  3TCA A;  4K81 A;  4A6F B;  3SYX A;  2LYD A;  1XD4 A;  4EJN A;  4HDO A;  1ZYI A;  3TVV A;  3OHM B;  5IRS A;  2D10 A;  3QWM A;  2Y8F A;  4XWX A;  1BTK A;  1Y5O A;  4WJ7 A;  1EVH A;  2RGN B;  4HAX B;  4QXA B;  2QKM A;  1EAZ A;  3A8Q A;  1MI1 A;  2CY5 A;  2V76 A;  3QBV B;  4ZRJ A;  1U2B A;  5C16 A;  1EF1 A;  2COD A;  3SV1 A;  2Z4D A;  4Y94 A;  3DXD A;  1TQZ A;  2G35 A;  1FGY A;  2DKP A;  2RUK B;  2D9Z A;  1XCG A;  4DBB A;  4KHA A;  2N0Y A;  1T77 A;  3TFM A;  4HAY B;  2HTH B;  3GYP A;  4NSW A;  2ELB A;  4KHB B;  2L1C A;  3FEH A;  1SHC A;  3FVC A;  3M1I B;  4K2O A;  4Z2M B;  3MPX A;  3GYO A;  3UZT A;  2W2X C;  3VOQ A;  5D3W A;  5DH9 B;  2LUL A;  3P6A A;  3DXC A;  2Z59 A;  2I1J A;  5LON B;  1E5W A;  1RJ2 A;  2LG1 A;  1NTY A;  1X05 A;  3D8F A;  1X1G A;  1B55 A;  5CLQ B;  1W1G A;  3P7Z A;  1K5G B;  2PZ1 A;  4GN1 A;  2D9Y A;  1J19 A;  2COF A;  1XOD A;  3PVL A;  4KVG B;  2GS0 A;  3KSY A;  2COA A;  5KQ1 A;  1U5D A;  3AJ4 A;  4DXA B;  1UNP A;  3A58 A;  2K2J A;  3KZ1 A;  3F0W A;  3HSA A;  3QIJ A;  2YT2 A;  4MY6 A;  1U29 A;  2KCJ A;  3D8E A;  5D3X A;  3HIE A;  1V5U A;  1MPH A;  1MK7 B;  4P7I A;  1WVH A;  1ZVR A;  5C5B B;  2YS1 A;  1V5P A;  2P8V A;  1UPR A;  5J3T A;  2COC A;  1V89 A;  2FJL A;  1Z87 A;  1AQC A;  3WYF B;  5JHH A;  5GOW B;  1BAK A;  4YL8 A;  2D2Q A;  4F7U P;  2N23 A;  2Q13 A;  2VKI A;  3OAN A;  5JLJ B;  1IRS A;  2RSG A;  1P3R A;  3MDB C;  2KR0 A;  1X11 A;  4F7G A;  1V88 A;  5CLL B;  2MKR A;  5LOP B;  4WSF A;  4WVF B;  2R2Y A;  1FHW A;  1U5G A;  4ZRI A;  4Z2N A;  1FOE A;  4A6H A;  1GC6 A;  2W2W A;  1MAI A;  4A6K A;  3PEG A;  2CAY A;  1NTV A;  4GXB A;  5I2M A;  2YT0 A;  4HHV A;  5FI0 A;  1PMS A;  4QJ4 B;  2DKQ A;  2Y7B A;  1GC7 A;  3DCX A;  2DLW A;  1DYN A;  1QC6 A;  2AEH A;  4HAZ B;  2Z0P A;  2GCJ A;  2KUP A;  4EKU A;  1NU2 A;  1ZM0 A;  1KZG A;  5D3Y A;  1PLS A;  2KUQ A;  2CY4 A;  1WGU A;  2AL6 A;  1NI2 A;  5JP4 A;  2Z0O A;  3V5W A;  3PG7 A;  5JHG A;  1V5M A;  1MK9 B;  1I2H A;  4C0A A;  3FSS A;  2K00 A;  3ZDT A;  4GZU A;  4BBK A;  2DN6 A;  1X86 A;  2EC1 A;  3BIN A;  3F5R A;  3U12 A;  1W1H A;  4K2P A;  2YT1 A;  2JP2 A;  1J0W A;  2YRY A;  2GJY A;  4HAU B;  4A5K A;  2ROZ B;  2YS5 A;  5J3Y A;  1DDV A;  4MT7 A;  2CRF A;  2LOZ A;  2RRF A;  1MIX A;  2K49 A;  3ODO A;  2W2X D;  1LB1 A;  1XX0 A;  2M38 A;  3KY9 A;  2K8E A;  4ZRK A;  1H10 A;  4B6H A;  4TKN A;  5DI9 B;  4YON A;  2D9X A;  4NY0 A;  1U5E A;  1W1D A;  1WJ1 A;  2J0J A;  3A98 B;  3AU5 A;  2VSZ A;  1OMW A;  3N7C A;  1XR0 B;  4MK0 A;  2I1K A;  1ISN A;  3HW2 B;  5C6R A;  2Z0Q A;  2DA0 A;  4D6W A;  1DDM A;  3B77 A;  1DBH A;  2GCL A;  1TXD A;  2HE7 A;  1AWE A;  3PSC A;  3LJU X;  1BWN A;  2KGX B;  2KIG A;  5KQ4 A;  2UZR A;  2DFK A;  1ZC4 B;  2K2U A;  3NSU A;  4GMV A;  2ELA A;  2MFQ A;  3IVF A;  2UVM A;  1FGZ A;  5HE0 A;  2P0D A;  2OQB A;  2IYB A;  3NWA A;  3RCP A;  2D4Q A;  1M7E A;  2DYN A;  1RRP B;  1H4R A;  2MWN B;  4HAT B;  3ODX A;  3PVU A;  2RNR B;  4OSN A;  2EJ8 A;  3T06 A;  3PP2 A;  4TYZ A;  3SUZ A;  1N3H A;  5EFX A;  5DIF B;  1K5D B;  4QJ5 B;  1FHO A;  1KI1 B;  1KZ7 A;  4HDQ A;  3ZVR A;  2BCJ A;  3VIA A;  5D3V A;  1UEF A;  2I5C A;  1DDW A;  5L81 A;  1FB8 A;  4H8S A;  3BJI A;  5HE1 A;  1ZSQ A;  2LKO A;  2EMS A;  2GUM A;  2MDX A;  2RLO A;  3WA0 A;  4CSQ A;  1PFJ A;  2H7E A;  5D27 A;  4GPT B;  3DXE A;  3NW8 A;  5C79 A;  3A8P A;  3ULC A;  1SGH A;  4K17 A;  2Y8G A;  4KHB A;  4GNK B;  1GG3 A;  2ZPY A;  1MKE A;  4PNK A;  2KIE A;  1LW3 A;  2X18 A;  3FM8 C;  2FJU B;  2D9V A;  4L6E A;  4HB2 B;  3ULB A;  4QJ3 B;  2J59 M;  4L1R A;  4CYE A;  5DHA B;  5M4Y B;  2OTX A;  3PVW A;  2ADZ A;  1XKE A;  2YF0 A;  3KRW A;  2EMT A;  2DX5 A;  3PZD A;  1M7R A;  2ZKM X;  3CIK A;  3NWF A;  2DYQ A;  5HE2 A;  1V61 A;  2NBV A;  2R0D A;  4HAV B;  1X1F A;  4IOY X;  2DHK A;  1I7A A;  4DX9 0;  1OY2 A;  2J0M A;  4EMO A;  5LG4 B;  1EGX A;  1WJM A;  2DHI A;  3NWD A;  5I2S A;  5J3Q A;  4GOU A;  2DHJ A;  2I5F A;  1TJ6 A;  1U27 A; 
#chains in the Genus database with same CATH homology
 4CHM A;  2YS3 A;  5C5B A;  4DX8 A;  2QKL A;  3U7D A;  2IFS A;  1UPQ A;  3ODW A;  2E2X A;  2RVB B;  1QQG A;  2YVC A;  2DX1 A;  2P0F A;  2DTC A;  5FI1 A;  1ZC3 B;  2UZS A;  3CXB B;  1MIZ B;  4HAW B;  4HB3 B;  1OQN A;  5DHF B;  4GMX B;  2D11 A;  1WI1 A;  3KRX A;  3G9W A;  1P6S A;  2M14 A;  2H7D A;  2P0H A;  3X23 A;  4KAX B;  1UNR A;  4KHO A;  4CHJ A;  1U5F A;  2NMB A;  2NZ8 B;  1BTN A;  3TW1 A;  4A6F A;  4F7H A;  2L2I A;  3HK0 A;  3HQC A;  4IFS A;  4PQ0 A;  3SO6 A;  1DRO A;  4IAP A;  1P5T A;  3U8Z A;  3D8D A;  4HB0 B;  3ML4 A;  1WG7 A;  2YSZ A;  3AU4 A;  2D9W A;  3O96 A;  5HE3 A;  2ROV A;  2VRW B;  1FHX A;  2XQN M;  1Y19 B;  1Q67 A;  1UNQ A;  1WGQ A;  3TO1 A;  4HB4 B;  2R09 A;  1FAO A;  2J0K A;  5KCV A;  3SNH A;  4D0N B;  2LOX A;  3TCA A;  4K81 A;  4A6F B;  3SYX A;  2LYD A;  1XD4 A;  4EJN A;  4HDO A;  3TVV A;  2D10 A;  3QWM A;  2Y8F A;  4XWX A;  1BTK A;  1Y5O A;  4WJ7 A;  1EVH A;  2RGN B;  4HAX B;  2QKM A;  1EAZ A;  3A8Q A;  3QBV B;  2CY5 A;  2V76 A;  4ZRJ A;  1U2B A;  5C16 A;  1EF1 A;  2COD A;  3SV1 A;  4Y94 A;  3DXD A;  1TQZ A;  2G35 A;  1FGY A;  2DKP A;  2RUK B;  2D9Z A;  1XCG A;  4DBB A;  4KHA A;  2N0Y A;  3TFM A;  4HAY B;  2HTH B;  3GYP A;  4NSW A;  2ELB A;  4KHB B;  2L1C A;  3FEH A;  1SHC A;  3M1I B;  4K2O A;  4Z2M B;  3MPX A;  3GYO A;  3UZT A;  2W2X C;  3VOQ A;  5D3W A;  5DH9 B;  2LUL A;  3P6A A;  3DXC A;  2I1J A;  5LON B;  1E5W A;  1RJ2 A;  2LG1 A;  1NTY A;  1X05 A;  3D8F A;  1X1G A;  1B55 A;  5CLQ B;  1W1G A;  3P7Z A;  1K5G B;  2PZ1 A;  4GN1 A;  2D9Y A;  1J19 A;  2COF A;  1XOD A;  3PVL A;  4KVG B;  2GS0 A;  3KSY A;  2COA A;  5KQ1 A;  1U5D A;  3AJ4 A;  4DXA B;  1UNP A;  2K2J A;  3KZ1 A;  3F0W A;  3QIJ A;  4MY6 A;  1U29 A;  2KCJ A;  3D8E A;  5D3X A;  1V5U A;  1MPH A;  1MK7 B;  4P7I A;  1WVH A;  1ZVR A;  5C5B B;  2YS1 A;  1V5P A;  2P8V A;  1UPR A;  5J3T A;  2COC A;  1V89 A;  2FJL A;  1Z87 A;  1AQC A;  3WYF B;  5JHH A;  5GOW B;  1BAK A;  4YL8 A;  2D2Q A;  4F7U P;  2N23 A;  2Q13 A;  2VKI A;  3OAN A;  5JLJ B;  1IRS A;  2RSG A;  1P3R A;  3MDB C;  4F7G A;  1X11 A;  1V88 A;  5CLL B;  2MKR A;  5LOP B;  4WSF A;  4WVF B;  1FHW A;  1U5G A;  4ZRI A;  4Z2N A;  1FOE A;  4A6H A;  1GC6 A;  2W2W A;  1MAI A;  4A6K A;  3PEG A;  2CAY A;  1NTV A;  4GXB A;  2YT0 A;  4HHV A;  5FI0 A;  1PMS A;  2DKQ A;  2Y7B A;  1GC7 A;  2DLW A;  1DYN A;  1QC6 A;  2AEH A;  4HAZ B;  2Z0P A;  2GCJ A;  2KUP A;  4EKU A;  1NU2 A;  1ZM0 A;  1KZG A;  5D3Y A;  1PLS A;  2CY4 A;  1WGU A;  2AL6 A;  1NI2 A;  5JP4 A;  2Z0O A;  3V5W A;  3PG7 A;  5JHG A;  1V5M A;  1MK9 B;  1I2H A;  4C0A A;  3FSS A;  2K00 A;  3ZDT A;  4GZU A;  4BBK A;  2DN6 A;  1X86 A;  2EC1 A;  3BIN A;  3F5R A;  1W1H A;  4K2P A;  2YT1 A;  2JP2 A;  1J0W A;  2YRY A;  2GJY A;  4HAU B;  4A5K A;  2ROZ B;  2YS5 A;  5J3Y A;  1DDV A;  4MT7 A;  2CRF A;  2LOZ A;  1MIX A;  3ODO A;  2W2X D;  1LB1 A;  1XX0 A;  2M38 A;  3KY9 A;  4ZRK A;  1H10 A;  4B6H A;  4TKN A;  5DI9 B;  4YON A;  2D9X A;  4NY0 A;  1U5E A;  1W1D A;  1WJ1 A;  2J0J A;  3A98 B;  3AU5 A;  2VSZ A;  1OMW A;  3N7C A;  1XR0 B;  4MK0 A;  2I1K A;  1ISN A;  3HW2 B;  5C6R A;  2Z0Q A;  2DA0 A;  1DDM A;  1DBH A;  2GCL A;  1TXD A;  2HE7 A;  1AWE A;  3PSC A;  3LJU X;  1BWN A;  2KGX B;  5KQ4 A;  2UZR A;  2DFK A;  1ZC4 B;  2K2U A;  3NSU A;  4GMV A;  2ELA A;  3IVF A;  2MFQ A;  2UVM A;  1FGZ A;  5HE0 A;  2P0D A;  2OQB A;  2IYB A;  3RCP A;  2D4Q A;  1M7E A;  2DYN A;  1RRP B;  1H4R A;  2MWN B;  4HAT B;  3ODX A;  3PVU A;  2RNR B;  2EJ8 A;  3T06 A;  3PP2 A;  4TYZ A;  3SUZ A;  1N3H A;  5EFX A;  5DIF B;  1K5D B;  1FHO A;  1KI1 B;  1KZ7 A;  4HDQ A;  3ZVR A;  2BCJ A;  3VIA A;  5D3V A;  1UEF A;  2I5C A;  1DDW A;  5L81 A;  1FB8 A;  4H8S A;  3BJI A;  5HE1 A;  1ZSQ A;  2LKO A;  2EMS A;  2MDX A;  2RLO A;  3WA0 A;  1PFJ A;  2H7E A;  5D27 A;  4GPT B;  3DXE A;  5C79 A;  3A8P A;  3ULC A;  1SGH A;  4K17 A;  2Y8G A;  1GG3 A;  2ZPY A;  1MKE A;  4PNK A;  1LW3 A;  2X18 A;  3FM8 C;  2D9V A;  4L6E A;  4HB2 B;  3ULB A;  2J59 M;  4CYE A;  5DHA B;  2OTX A;  3PVW A;  2ADZ A;  1XKE A;  2YF0 A;  3KRW A;  2EMT A;  2DX5 A;  3PZD A;  1M7R A;  3CIK A;  2DYQ A;  5HE2 A;  1V61 A;  2R0D A;  4HAV B;  1X1F A;  4IOY X;  2DHK A;  1I7A A;  4DX9 0;  1OY2 A;  2J0M A;  4EMO A;  1EGX A;  1WJM A;  2DHI A;  5J3Q A;  2DHJ A;  2I5F A;  1TJ6 A;  1U27 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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