2VKIA

Structure of the pdk1 ph domain k465e mutant
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
139
structure length
139
Chain Sequence
SNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDERKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRYQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mutation of the Pdk1 Ph Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance.
pubmed doi rcsb
molecule keywords 3-PHOPSHOINOSITIDE DEPENDENT PROTEIN KINASE 1
molecule tags Transferase
source organism Homo sapiens
total genus 39
structure length 139
sequence length 139
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-12-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14593 PH_3 PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 2vkiA00
1W1GA 2LOZA 4WJ7A 1J19A 2N0YA 3TW1A 2EC1A 3SO6A 1U5DA 4DX8A 2YVCA 4F7UP 2QKMA 1UPRA 2UVMA 3M1IB 5J3YA 3F5RA 5C16A 1U27A 1IRSA 3ODWA 5DHFB 4A6HA 3QWMA 2R09A 4CYEA 3PVLA 3KRWA 2MWNB 1EF1A 2OTXA 1RJ2A 3ML4A 2CODA 4K2PA 4ZRIA 2KCJA 2I1KA 2J0MA 2M14A 3SYXA 4KHOA 2RGNB 1XODA 5C79A 1WI1A 1U5EA 1GC6A 4DBBA 1RRPB 5JHGA 3ZVRA 3MPXA 1X86A 2RNRB 5J3QA 3PEGA 5DIFB 4MK0A 2W2XC 1OQNA 5HE0A 1BAKA 4Y94A 1PFJA 4HDOA 3FEHA 2LKOA 4CHJA 4KVGB 5JHHA 1X1FA 2D10A 4HB2B 3VIAA 2J0JA 5DHAB 2RVBB 2DHKA 5DI9B 2AL6A 2KGXB 5EFXA 2MDXA 4HAVB 5J3TA 2GS0A 1P3RA 1H10A 2MKRA 1UPQA 1W1HA 3ULBA 1EGXA 1V61A 4HAUB 4GPTB 2ZPYA 1U5FA 2VRWB 1I7AA 4HB3B 3BINA 2YS1A 1V88A 4EMOA 1NTYA 3QIJA 1FB8A 2DHJA 1K5DB 2H7DA 5FI1A 1H4RA 2X18A 3DXCA 2ROVA 2D9XA 5C5BB 1X1GA 3DXEA 4IFSA 2G35A 3CIKA 2UZSA 4HAWB 2K00A 1Q67A 1KI1B 1PMSA 1ISNA 2N23A 4GXBA 1I2HA 2OQBA 2V76A 3A8QA 1DROA 2CRFA 4EKUA 4K17A 2DYQA 1TQZA 4GMXB 1FGYA 2YT0A 3O96A 2COAA 5KQ1A 1BWNA 4BBKA 2BCJA 2I1JA 2RLOA 1X11A 2FJLA 3D8FA 1Z87A 3NSUA 5LONB 1NTVA 2J0KA 2P0HA 4GN1A 4HAZB 1GC7A 2DN6A 2COFA 4F7GA 2P0DA 2DFKA 2M38A 3HW2B 3ULCA 4GZUA 2DYNA 4MT7A 2D9VA 3PVWA 1DDVA 3PG7A 4Z2NA 4HDQA 2D2QA 5C6RA 2DKQA 4PQ0A 4MY6A 4KAXB 2ELAA 2D11A 4A6FB 2Y8GA 1V5MA 2W2XD 5HE3A 1ZSQA 3TO1A 1XCGA 1BTKA 3PSCA 1DYNA 1MK9B 2DX1A 5KCVA 3FM8C 4Z2MB 1WVHA 1FGZA 4WSFA 4A6FA 4HAXB 1MKEA 1NI2A 2Q13A 2E2XA 1P5TA 1KZ7A 1U5GA 1ZVRA 3BJIA 2I5FA 2LOXA 4CHMA 2D4QA 4TYZA 1FHWA 1ZM0A 4ZRKA 2RSGA 3KRXA 1XD4A 4TKNA 1OMWA 2CY4A 1SHCA 1K5GB 1LW3A 2EMTA 4HB0B 1LB1A 2YRYA 2R0DA 3AU4A 3HK0A 3CXBB 1PLSA 5D3WA 1MIXA 4GMVA 2ADZA 3TFMA 2DX5A 1WGUA 1DBHA 2D9YA 2HE7A 2VSZA 5L81A 1XR0B 4WVFB 5D27A 4D0NB 3MDBC 1V5PA 2H7EA 1KZGA 2DHIA 3D8DA 3DXDA 4P7IA 2QKLA 2LG1A 5LOPB 2MFQA 3IVFA 2KUPA 5HE2A 5CLQB 1QQGA 2RUKB 5JLJB 1FHXA 1U2BA 5C5BA 4HAYB 5DH9B 3GYOA 3D8EA 4HB4B 3GYPA 4ZRJA 3FSSA 1DDWA 2VKIA 3N7CA 5CLLB 3RCPA 2CY5A 4YONA 2YT1A 3X23A 3G9WA 3SUZA 1NU2A 1SGHA 1WJ1A 2L1CA 3P7ZA 3ODXA 4HHVA 3HQCA 1AQCA 1WJMA 2XQNM 2EJ8A 2COCA 5JP4A 5D3XA 2Z0QA 1TJ6A 1OY2A 2EMSA 1FOEA 3VOQA 2DTCA 3T06A 3UZTA 4EJNA 3ODOA 2JP2A 3P6AA 1TXDA 4A6KA 2IYBA 5GOWB 3SNHA 3KY9A 3U7DA 1AWEA 4XWXA 4DXAB 2LULA 1Y5OA 3A8PA 2HTHB 4IAPA 2Z0PA 3OANA 2I5CA 4H8SA 4YL8A 1FAOA 4F7HA 3PVUA 2YS3A 1GG3A 4KHAA 4HATB 2PZ1A 2GCJA 1U29A 3ZDTA 2IFSA 5HE1A 2GCLA 1MIZB 2W2WA 1V89A 2D9ZA 3QBVB 1XKEA 1EVHA 2YS5A 2ELBA 1B55A 4C0AA 2K2JA 2NMBA 3V5WA 1V5UA 1M7RA 4DX90 1DDMA 2YSZA 3WYFB 2ROZB 3AU5A 2Y8FA 1FHOA 2DKPA 1J0WA 4NSWA 2NZ8B 3AJ4A 1ZC3B 4KHBB 4A5KA 3PP2A 1UNQA 3TCAA 1W1DA 4K81A 1M7EA 1MK7B 2CAYA 2DLWA 2YF0A 3PZDA 3KSYA 4PNKA 2L2IA 3KZ1A 1EAZA 3A98B 5D3YA 1UNRA 4L6EA 3U8ZA 1ZC4B 1WG7A 2J59M 1MAIA 2Z0OA 4B6HA 2UZRA 1XX0A 3SV1A 3TVVA 4K2OA 2P0FA 3F0WA 2K2UA 1MPHA 3LJUX 2P8VA 1WGQA 2D9WA 2DA0A 1P6SA 5D3VA 2Y7BA 1X05A 1BTNA 1N3HA 5FI0A 2GJYA 4NY0A 2LYDA 1QC6A 1Y19B 5KQ4A 1E5WA 2AEHA 4IOYX 3WA0A 1UNPA 1UEFA
chains in the Genus database with same CATH superfamily
1W1GA 2LOZA 4WJ7A 1J19A 2N0YA 3TW1A 2EC1A 3SO6A 1U5DA 4DX8A 2YVCA 4F7UP 1ZYIA 2QKMA 1UPRA 2UVMA 3M1IB 5J3YA 3F5RA 5C16A 1U27A 1IRSA 3ODWA 5DHFB 4A6HA 3HSAA 3QWMA 2R09A 4CYEA 3PVLA 3KRWA 2MWNB 1EF1A 2OTXA 1RJ2A 5IRSA 1T77A 4HSIA 3ML4A 2CODA 4K2PA 4ZRIA 2KCJA 2I1KA 2J0MA 2M14A 3SYXA 4KHOA 2GUMA 2RGNB 1XODA 2K49A 1WI1A 3NWFA 5C79A 1U5EA 1GC6A 4DBBA 1RRPB 5JHGA 3ZVRA 3MPXA 1X86A 2RNRB 5J3QA 3PEGA 5DIFB 4MK0A 2W2XC 1OQNA 5HE0A 1BAKA 4Y94A 1PFJA 4HDOA 3FEHA 2LKOA 4CHJA 3OHMB 2KR0A 4KVGB 5JHHA 1X1FA 2D10A 4HB2B 3VIAA 2J0JA 5DHAB 2RVBB 2DHKA 5DI9B 2AL6A 2KGXB 5EFXA 2MDXA 4HAVB 5J3TA 2GS0A 1P3RA 1H10A 2MKRA 1UPQA 1W1HA 3NWAA 3ULBA 1EGXA 1V61A 4HAUB 4GPTB 2ZPYA 1U5FA 2VRWB 1I7AA 4HB3B 3BINA 2YS1A 1V88A 4EMOA 1NTYA 3QIJA 4KHBA 1FB8A 2DHJA 1K5DB 2H7DA 5FI1A 2Z4DA 1H4RA 2X18A 3DXCA 2ROVA 2D9XA 5C5BB 1X1GA 3DXEA 1MI1A 4IFSA 2G35A 3CIKA 2UZSA 4HAWB 2K00A 3FVCA 1Q67A 1KI1B 1PMSA 1ISNA 2N23A 4GXBA 1I2HA 2OQBA 4GNKB 2V76A 3A8QA 5I2MA 1DROA 2CRFA 4EKUA 4K17A 2DYQA 1TQZA 4GMXB 1FGYA 2YT0A 3O96A 4OT1A 2COAA 5KQ1A 1BWNA 4BBKA 2BCJA 2I1JA 2RLOA 1X11A 2FJLA 3D8FA 1Z87A 3NSUA 5LONB 1NTVA 2J0KA 2P0HA 4GN1A 4HAZB 1GC7A 2DN6A 2COFA 4F7GA 2P0DA 2DFKA 2M38A 3HW2B 3ULCA 4GZUA 2DYNA 4MT7A 2D9VA 3PVWA 1DDVA 3PG7A 4Z2NA 4HDQA 2D2QA 5C6RA 2DKQA 4PQ0A 4MY6A 4KAXB 2ELAA 2D11A 3HIEA 4A6FB 2Y8GA 1V5MA 2W2XD 5HE3A 1ZSQA 3TO1A 1XCGA 1BTKA 3PSCA 1DYNA 1MK9B 4CSQA 2DX1A 5KCVA 3FM8C 4Z2MB 3NWDA 1WVHA 1FGZA 3NW8A 4WSFA 4A6FA 4HAXB 1MKEA 3U12A 1NI2A 2Q13A 2E2XA 1P5TA 1KZ7A 1U5GA 1ZVRA 3BJIA 2I5FA 2LOXA 4CHMA 2D4QA 4TYZA 1FHWA 1ZM0A 2KIGA 2RSGA 4ZRKA 3KRXA 1XD4A 2ZKMX 1OMWA 2CY4A 4TKNA 2R2YA 1SHCA 1K5GB 5LG4B 1LW3A 2EMTA 4HB0B 1LB1A 4QXAB 2YRYA 4QJ5B 2R0DA 3AU4A 3HK0A 3CXBB 1PLSA 2Z13A 5D3WA 1MIXA 4GMVA 2ADZA 3TFMA 2DX5A 1WGUA 1DBHA 2D9YA 2HE7A 2NBVA 2VSZA 5L81A 1XR0B 4WVFB 5D27A 4D0NB 3MDBC 1V5PA 2H7EA 1KZGA 2DHIA 3D8DA 3DXDA 3A58A 4P7IA 2QKLA 2LG1A 5LOPB 3B77A 2MFQA 3IVFA 2KUPA 5HE2A 5CLQB 1QQGA 2RUKB 5JLJB 1FHXA 1U2BA 5C5BA 4HAYB 5DH9B 3GYOA 3D8EA 4L1RA 4HB4B 3GYPA 4ZRJA 3FSSA 1DDWA 2VKIA 3N7CA 5CLLB 3RCPA 2CY5A 4YONA 2YT1A 3X23A 3G9WA 3SUZA 1NU2A 1SGHA 1WJ1A 2L1CA 3P7ZA 4QJ4B 3ODXA 4HHVA 3HQCA 1AQCA 4D6WA 1WJMA 2XQNM 2EJ8A 2COCA 5JP4A 5D3XA 2Z0QA 1TJ6A 1OY2A 2EMSA 4GOUA 1FOEA 3VOQA 2DTCA 3T06A 3UZTA 4EJNA 3ODOA 2JP2A 3P6AA 1TXDA 4A6KA 2IYBA 5GOWB 3SNHA 3KY9A 5I2SA 5M4YB 3U7DA 1AWEA 4XWXA 4DXAB 2LULA 1Y5OA 3A8PA 2Z14A 2HTHB 4IAPA 2Z0PA 3OANA 2I5CA 4H8SA 4YL8A 1FAOA 4F7HA 3PVUA 2YS3A 1GG3A 4KHAA 4HATB 2PZ1A 2GCJA 1U29A 3ZDTA 2IFSA 2K8EA 5HE1A 2GCLA 1MIZB 2W2WA 2FJUB 1V89A 2D9ZA 3QBVB 1XKEA 1EVHA 2YS5A 2ELBA 1B55A 4C0AA 2K2JA 2NMBA 2Z59A 3V5WA 1V5UA 1M7RA 4DX90 1DDMA 2YSZA 2YT2A 3WYFB 2ROZB 3AU5A 2Y8FA 1FHOA 2DKPA 1J0WA 4NSWA 2NZ8B 3AJ4A 1ZC3B 4KHBB 4A5KA 3PP2A 2KUQA 1UNQA 3TCAA 1W1DA 4K81A 2KIEA 1M7EA 1MK7B 2CAYA 2DLWA 2YF0A 3PZDA 3KSYA 4OSNA 4PNKA 2L2IA 3KZ1A 1EAZA 3A98B 5D3YA 1UNRA 4L6EA 3U8ZA 1ZC4B 1WG7A 2RRFA 2J59M 1MAIA 2Z0OA 4B6HA 2UZRA 1XX0A 3SV1A 3TVVA 4K2OA 2P0FA 3F0WA 4DIXA 2K2UA 1MPHA 3LJUX 3DCXA 2P8VA 1WGQA 2D9WA 2DA0A 1P6SA 5D3VA 2Y7BA 1X05A 1BTNA 1N3HA 5FI0A 2GJYA 4NY0A 2LYDA 1QC6A 1Y19B 5KQ4A 1E5WA 2AEHA 4IOYX 4QJ3B 3WA0A 1UNPA 1UEFA
chains in the Genus database with same CATH topology
1W1GA 2LOZA 4WJ7A 1J19A 2N0YA 3TW1A 2EC1A 3SO6A 1U5DA 4DX8A 2YVCA 4F7UP 2QKMA 1UPRA 2UVMA 3M1IB 5J3YA 3F5RA 5C16A 1U27A 1IRSA 3ODWA 5DHFB 4A6HA 3QWMA 2R09A 4CYEA 3PVLA 3KRWA 2MWNB 1EF1A 2OTXA 1RJ2A 3ML4A 2CODA 4K2PA 4ZRIA 2KCJA 2I1KA 2J0MA 2M14A 3SYXA 4KHOA 2RGNB 1XODA 5C79A 1WI1A 1U5EA 1GC6A 4DBBA 1RRPB 5JHGA 3ZVRA 3MPXA 1X86A 2RNRB 5J3QA 3PEGA 5DIFB 4MK0A 2W2XC 1OQNA 5HE0A 1BAKA 4Y94A 1PFJA 4HDOA 3FEHA 2LKOA 4CHJA 4KVGB 5JHHA 1X1FA 2D10A 4HB2B 3VIAA 2J0JA 5DHAB 2RVBB 2DHKA 5DI9B 2AL6A 2KGXB 5EFXA 2MDXA 4HAVB 5J3TA 2GS0A 1P3RA 1H10A 2MKRA 1UPQA 1W1HA 3ULBA 1EGXA 1V61A 4HAUB 4GPTB 2ZPYA 1U5FA 2VRWB 1I7AA 4HB3B 3BINA 2YS1A 1V88A 4EMOA 1NTYA 3QIJA 1FB8A 2DHJA 1K5DB 2H7DA 5FI1A 1H4RA 2X18A 3DXCA 2ROVA 2D9XA 5C5BB 1X1GA 3DXEA 4IFSA 2G35A 3CIKA 2UZSA 4HAWB 2K00A 1Q67A 1KI1B 1PMSA 1ISNA 2N23A 4GXBA 1I2HA 2OQBA 2V76A 3A8QA 1DROA 2CRFA 4EKUA 4K17A 2DYQA 1TQZA 4GMXB 1FGYA 2YT0A 3O96A 2COAA 5KQ1A 1BWNA 4BBKA 2BCJA 2I1JA 2RLOA 1X11A 2FJLA 3D8FA 1Z87A 3NSUA 5LONB 1NTVA 2J0KA 2P0HA 4GN1A 4HAZB 1GC7A 2DN6A 2COFA 4F7GA 2P0DA 2DFKA 2M38A 3HW2B 3ULCA 4GZUA 2DYNA 4MT7A 2D9VA 3PVWA 1DDVA 3PG7A 4Z2NA 4HDQA 2D2QA 5C6RA 2DKQA 4PQ0A 4MY6A 4KAXB 2ELAA 2D11A 4A6FB 2Y8GA 1V5MA 2W2XD 5HE3A 1ZSQA 3TO1A 1XCGA 1BTKA 3PSCA 1DYNA 1MK9B 2DX1A 5KCVA 3FM8C 4Z2MB 1WVHA 1FGZA 4WSFA 4A6FA 4HAXB 1MKEA 1NI2A 2Q13A 2E2XA 1P5TA 1KZ7A 1U5GA 1ZVRA 3BJIA 2I5FA 2LOXA 4CHMA 2D4QA 4TYZA 1FHWA 1ZM0A 4ZRKA 2RSGA 3KRXA 1XD4A 4TKNA 1OMWA 2CY4A 1SHCA 1K5GB 1LW3A 2EMTA 4HB0B 1LB1A 2YRYA 2R0DA 3AU4A 3HK0A 3CXBB 1PLSA 5D3WA 1MIXA 4GMVA 2ADZA 3TFMA 2DX5A 1WGUA 1DBHA 2D9YA 2HE7A 2VSZA 5L81A 1XR0B 4WVFB 5D27A 4D0NB 3MDBC 1V5PA 2H7EA 1KZGA 2DHIA 3D8DA 3DXDA 4P7IA 2QKLA 2LG1A 5LOPB 2MFQA 3IVFA 2KUPA 5HE2A 5CLQB 1QQGA 2RUKB 5JLJB 1FHXA 1U2BA 5C5BA 4HAYB 5DH9B 3GYOA 3D8EA 4HB4B 3GYPA 4ZRJA 3FSSA 1DDWA 2VKIA 3N7CA 5CLLB 3RCPA 2CY5A 4YONA 2YT1A 3X23A 3G9WA 3SUZA 1NU2A 1SGHA 1WJ1A 2L1CA 3P7ZA 3ODXA 4HHVA 3HQCA 1AQCA 1WJMA 2XQNM 2EJ8A 2COCA 5JP4A 5D3XA 2Z0QA 1TJ6A 1OY2A 2EMSA 1FOEA 3VOQA 2DTCA 3T06A 3UZTA 4EJNA 3ODOA 2JP2A 3P6AA 1TXDA 4A6KA 2IYBA 5GOWB 3SNHA 3KY9A 3U7DA 1AWEA 4XWXA 4DXAB 2LULA 1Y5OA 3A8PA 2HTHB 4IAPA 2Z0PA 3OANA 2I5CA 4H8SA 4YL8A 1FAOA 4F7HA 3PVUA 2YS3A 1GG3A 4KHAA 4HATB 2PZ1A 2GCJA 1U29A 3ZDTA 2IFSA 5HE1A 2GCLA 1MIZB 2W2WA 1V89A 2D9ZA 3QBVB 1XKEA 1EVHA 2YS5A 2ELBA 1B55A 4C0AA 2K2JA 2NMBA 3V5WA 1V5UA 1M7RA 4DX90 1DDMA 2YSZA 3WYFB 2ROZB 3AU5A 2Y8FA 1FHOA 2DKPA 1J0WA 4NSWA 2NZ8B 3AJ4A 1ZC3B 4KHBB 4A5KA 3PP2A 1UNQA 3TCAA 1W1DA 4K81A 1M7EA 1MK7B 2CAYA 2DLWA 2YF0A 3PZDA 3KSYA 4PNKA 2L2IA 3KZ1A 1EAZA 3A98B 5D3YA 1UNRA 4L6EA 3U8ZA 1ZC4B 1WG7A 2J59M 1MAIA 2Z0OA 4B6HA 2UZRA 1XX0A 3SV1A 3TVVA 4K2OA 2P0FA 3F0WA 2K2UA 1MPHA 3LJUX 2P8VA 1WGQA 2D9WA 2DA0A 1P6SA 5D3VA 2Y7BA 1X05A 1BTNA 1N3HA 5FI0A 2GJYA 4NY0A 2LYDA 1QC6A 1Y19B 5KQ4A 1E5WA 2AEHA 4IOYX 3WA0A 1UNPA 1UEFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W1G A;  2LOZ A;  4WJ7 A;  1J19 A;  2N0Y A;  3TW1 A;  2EC1 A;  3SO6 A;  1U5D A;  4DX8 A;  2YVC A;  4F7U P;  2QKM A;  1UPR A;  2UVM A;  3M1I B;  5J3Y A;  3F5R A;  5C16 A;  1U27 A;  1IRS A;  3ODW A;  5DHF B;  4A6H A;  3QWM A;  2R09 A;  4CYE A;  3PVL A;  3KRW A;  2MWN B;  1EF1 A;  2OTX A;  1RJ2 A;  3ML4 A;  2COD A;  4K2P A;  4ZRI A;  2KCJ A;  2I1K A;  2J0M A;  2M14 A;  3SYX A;  4KHO A;  2RGN B;  1XOD A;  5C79 A;  1WI1 A;  1U5E A;  1GC6 A;  4DBB A;  1RRP B;  5JHG A;  3ZVR A;  3MPX A;  1X86 A;  2RNR B;  5J3Q A;  3PEG A;  5DIF B;  4MK0 A;  2W2X C;  1OQN A;  5HE0 A;  1BAK A;  4Y94 A;  1PFJ A;  4HDO A;  3FEH A;  2LKO A;  4CHJ A;  4KVG B;  5JHH A;  1X1F A;  2D10 A;  4HB2 B;  3VIA A;  2J0J A;  5DHA B;  2RVB B;  2DHK A;  5DI9 B;  2AL6 A;  2KGX B;  5EFX A;  2MDX A;  4HAV B;  5J3T A;  2GS0 A;  1P3R A;  1H10 A;  2MKR A;  1UPQ A;  1W1H A;  3ULB A;  1EGX A;  1V61 A;  4HAU B;  4GPT B;  2ZPY A;  1U5F A;  2VRW B;  1I7A A;  4HB3 B;  3BIN A;  2YS1 A;  1V88 A;  4EMO A;  1NTY A;  3QIJ A;  1FB8 A;  2DHJ A;  1K5D B;  2H7D A;  5FI1 A;  1H4R A;  2X18 A;  3DXC A;  2ROV A;  2D9X A;  5C5B B;  1X1G A;  3DXE A;  4IFS A;  2G35 A;  3CIK A;  2UZS A;  4HAW B;  2K00 A;  1Q67 A;  1KI1 B;  1PMS A;  1ISN A;  2N23 A;  4GXB A;  1I2H A;  2OQB A;  2V76 A;  3A8Q A;  1DRO A;  2CRF A;  4EKU A;  4K17 A;  2DYQ A;  1TQZ A;  4GMX B;  1FGY A;  2YT0 A;  3O96 A;  2COA A;  5KQ1 A;  1BWN A;  4BBK A;  2BCJ A;  2I1J A;  2RLO A;  1X11 A;  2FJL A;  3D8F A;  1Z87 A;  3NSU A;  5LON B;  1NTV A;  2J0K A;  2P0H A;  4GN1 A;  4HAZ B;  1GC7 A;  2DN6 A;  2COF A;  4F7G A;  2P0D A;  2DFK A;  2M38 A;  3HW2 B;  3ULC A;  4GZU A;  2DYN A;  4MT7 A;  2D9V A;  3PVW A;  1DDV A;  3PG7 A;  4Z2N A;  4HDQ A;  2D2Q A;  5C6R A;  2DKQ A;  4PQ0 A;  4MY6 A;  4KAX B;  2ELA A;  2D11 A;  4A6F B;  2Y8G A;  1V5M A;  2W2X D;  5HE3 A;  1ZSQ A;  3TO1 A;  1XCG A;  1BTK A;  3PSC A;  1DYN A;  1MK9 B;  2DX1 A;  5KCV A;  3FM8 C;  4Z2M B;  1WVH A;  1FGZ A;  4WSF A;  4A6F A;  4HAX B;  1MKE A;  1NI2 A;  2Q13 A;  2E2X A;  1P5T A;  1KZ7 A;  1U5G A;  1ZVR A;  3BJI A;  2I5F A;  2LOX A;  4CHM A;  2D4Q A;  4TYZ A;  1FHW A;  1ZM0 A;  4ZRK A;  2RSG A;  3KRX A;  1XD4 A;  4TKN A;  1OMW A;  2CY4 A;  1SHC A;  1K5G B;  1LW3 A;  2EMT A;  4HB0 B;  1LB1 A;  2YRY A;  2R0D A;  3AU4 A;  3HK0 A;  3CXB B;  1PLS A;  5D3W A;  1MIX A;  4GMV A;  2ADZ A;  3TFM A;  2DX5 A;  1WGU A;  1DBH A;  2D9Y A;  2HE7 A;  2VSZ A;  5L81 A;  1XR0 B;  4WVF B;  5D27 A;  4D0N B;  3MDB C;  1V5P A;  2H7E A;  1KZG A;  2DHI A;  3D8D A;  3DXD A;  4P7I A;  2QKL A;  2LG1 A;  5LOP B;  2MFQ A;  3IVF A;  2KUP A;  5HE2 A;  5CLQ B;  1QQG A;  2RUK B;  5JLJ B;  1FHX A;  1U2B A;  5C5B A;  4HAY B;  5DH9 B;  3GYO A;  3D8E A;  4HB4 B;  3GYP A;  4ZRJ A;  3FSS A;  1DDW A;  2VKI A;  3N7C A;  5CLL B;  3RCP A;  2CY5 A;  4YON A;  2YT1 A;  3X23 A;  3G9W A;  3SUZ A;  1NU2 A;  1SGH A;  1WJ1 A;  2L1C A;  3P7Z A;  3ODX A;  4HHV A;  3HQC A;  1AQC A;  1WJM A;  2XQN M;  2EJ8 A;  2COC A;  5JP4 A;  5D3X A;  2Z0Q A;  1TJ6 A;  1OY2 A;  2EMS A;  1FOE A;  3VOQ A;  2DTC A;  3T06 A;  3UZT A;  4EJN A;  3ODO A;  2JP2 A;  3P6A A;  1TXD A;  4A6K A;  2IYB A;  5GOW B;  3SNH A;  3KY9 A;  3U7D A;  1AWE A;  4XWX A;  4DXA B;  2LUL A;  1Y5O A;  3A8P A;  2HTH B;  4IAP A;  2Z0P A;  3OAN A;  2I5C A;  4H8S A;  4YL8 A;  1FAO A;  4F7H A;  3PVU A;  2YS3 A;  1GG3 A;  4KHA A;  4HAT B;  2PZ1 A;  2GCJ A;  1U29 A;  3ZDT A;  2IFS A;  5HE1 A;  2GCL A;  1MIZ B;  2W2W A;  1V89 A;  2D9Z A;  3QBV B;  1XKE A;  1EVH A;  2YS5 A;  2ELB A;  1B55 A;  4C0A A;  2K2J A;  2NMB A;  3V5W A;  1V5U A;  1M7R A;  4DX9 0;  1DDM A;  2YSZ A;  3WYF B;  2ROZ B;  3AU5 A;  2Y8F A;  1FHO A;  2DKP A;  1J0W A;  4NSW A;  2NZ8 B;  3AJ4 A;  1ZC3 B;  4KHB B;  4A5K A;  3PP2 A;  1UNQ A;  3TCA A;  1W1D A;  4K81 A;  1M7E A;  1MK7 B;  2CAY A;  2DLW A;  2YF0 A;  3PZD A;  3KSY A;  4PNK A;  2L2I A;  3KZ1 A;  1EAZ A;  3A98 B;  5D3Y A;  1UNR A;  4L6E A;  3U8Z A;  1ZC4 B;  1WG7 A;  2J59 M;  1MAI A;  2Z0O A;  4B6H A;  2UZR A;  1XX0 A;  3SV1 A;  3TVV A;  4K2O A;  2P0F A;  3F0W A;  2K2U A;  1MPH A;  3LJU X;  2P8V A;  1WGQ A;  2D9W A;  2DA0 A;  1P6S A;  5D3V A;  2Y7B A;  1X05 A;  1BTN A;  1N3H A;  5FI0 A;  2GJY A;  4NY0 A;  2LYD A;  1QC6 A;  1Y19 B;  5KQ4 A;  1E5W A;  2AEH A;  4IOY X;  3WA0 A;  1UNP A;  1UEF A; 
#chains in the Genus database with same CATH topology
 1W1G A;  2LOZ A;  4WJ7 A;  1J19 A;  2N0Y A;  3TW1 A;  2EC1 A;  3SO6 A;  1U5D A;  4DX8 A;  2YVC A;  4F7U P;  1ZYI A;  2QKM A;  1UPR A;  2UVM A;  3M1I B;  5J3Y A;  3F5R A;  5C16 A;  1U27 A;  1IRS A;  3ODW A;  5DHF B;  4A6H A;  3HSA A;  3QWM A;  2R09 A;  4CYE A;  3PVL A;  3KRW A;  2MWN B;  1EF1 A;  2OTX A;  1RJ2 A;  5IRS A;  1T77 A;  4HSI A;  3ML4 A;  2COD A;  4K2P A;  4ZRI A;  2KCJ A;  2I1K A;  2J0M A;  2M14 A;  3SYX A;  4KHO A;  2GUM A;  2RGN B;  1XOD A;  2K49 A;  1WI1 A;  3NWF A;  5C79 A;  1U5E A;  1GC6 A;  4DBB A;  1RRP B;  5JHG A;  3ZVR A;  3MPX A;  1X86 A;  2RNR B;  5J3Q A;  3PEG A;  5DIF B;  4MK0 A;  2W2X C;  1OQN A;  5HE0 A;  1BAK A;  4Y94 A;  1PFJ A;  4HDO A;  3FEH A;  2LKO A;  4CHJ A;  3OHM B;  2KR0 A;  4KVG B;  5JHH A;  1X1F A;  2D10 A;  4HB2 B;  3VIA A;  2J0J A;  5DHA B;  2RVB B;  2DHK A;  5DI9 B;  2AL6 A;  2KGX B;  5EFX A;  2MDX A;  4HAV B;  5J3T A;  2GS0 A;  1P3R A;  1H10 A;  2MKR A;  1UPQ A;  1W1H A;  3NWA A;  3ULB A;  1EGX A;  1V61 A;  4HAU B;  4GPT B;  2ZPY A;  1U5F A;  2VRW B;  1I7A A;  4HB3 B;  3BIN A;  2YS1 A;  1V88 A;  4EMO A;  1NTY A;  3QIJ A;  4KHB A;  1FB8 A;  2DHJ A;  1K5D B;  2H7D A;  5FI1 A;  2Z4D A;  1H4R A;  2X18 A;  3DXC A;  2ROV A;  2D9X A;  5C5B B;  1X1G A;  3DXE A;  1MI1 A;  4IFS A;  2G35 A;  3CIK A;  2UZS A;  4HAW B;  2K00 A;  3FVC A;  1Q67 A;  1KI1 B;  1PMS A;  1ISN A;  2N23 A;  4GXB A;  1I2H A;  2OQB A;  4GNK B;  2V76 A;  3A8Q A;  5I2M A;  1DRO A;  2CRF A;  4EKU A;  4K17 A;  2DYQ A;  1TQZ A;  4GMX B;  1FGY A;  2YT0 A;  3O96 A;  4OT1 A;  2COA A;  5KQ1 A;  1BWN A;  4BBK A;  2BCJ A;  2I1J A;  2RLO A;  1X11 A;  2FJL A;  3D8F A;  1Z87 A;  3NSU A;  5LON B;  1NTV A;  2J0K A;  2P0H A;  4GN1 A;  4HAZ B;  1GC7 A;  2DN6 A;  2COF A;  4F7G A;  2P0D A;  2DFK A;  2M38 A;  3HW2 B;  3ULC A;  4GZU A;  2DYN A;  4MT7 A;  2D9V A;  3PVW A;  1DDV A;  3PG7 A;  4Z2N A;  4HDQ A;  2D2Q A;  5C6R A;  2DKQ A;  4PQ0 A;  4MY6 A;  4KAX B;  2ELA A;  2D11 A;  3HIE A;  4A6F B;  2Y8G A;  1V5M A;  2W2X D;  5HE3 A;  1ZSQ A;  3TO1 A;  1XCG A;  1BTK A;  3PSC A;  1DYN A;  1MK9 B;  4CSQ A;  2DX1 A;  5KCV A;  3FM8 C;  4Z2M B;  3NWD A;  1WVH A;  1FGZ A;  3NW8 A;  4WSF A;  4A6F A;  4HAX B;  1MKE A;  3U12 A;  1NI2 A;  2Q13 A;  2E2X A;  1P5T A;  1KZ7 A;  1U5G A;  1ZVR A;  3BJI A;  2I5F A;  2LOX A;  4CHM A;  2D4Q A;  4TYZ A;  1FHW A;  1ZM0 A;  2KIG A;  2RSG A;  4ZRK A;  3KRX A;  1XD4 A;  2ZKM X;  1OMW A;  2CY4 A;  4TKN A;  2R2Y A;  1SHC A;  1K5G B;  5LG4 B;  1LW3 A;  2EMT A;  4HB0 B;  1LB1 A;  4QXA B;  2YRY A;  4QJ5 B;  2R0D A;  3AU4 A;  3HK0 A;  3CXB B;  1PLS A;  2Z13 A;  5D3W A;  1MIX A;  4GMV A;  2ADZ A;  3TFM A;  2DX5 A;  1WGU A;  1DBH A;  2D9Y A;  2HE7 A;  2NBV A;  2VSZ A;  5L81 A;  1XR0 B;  4WVF B;  5D27 A;  4D0N B;  3MDB C;  1V5P A;  2H7E A;  1KZG A;  2DHI A;  3D8D A;  3DXD A;  3A58 A;  4P7I A;  2QKL A;  2LG1 A;  5LOP B;  3B77 A;  2MFQ A;  3IVF A;  2KUP A;  5HE2 A;  5CLQ B;  1QQG A;  2RUK B;  5JLJ B;  1FHX A;  1U2B A;  5C5B A;  4HAY B;  5DH9 B;  3GYO A;  3D8E A;  4L1R A;  4HB4 B;  3GYP A;  4ZRJ A;  3FSS A;  1DDW A;  2VKI A;  3N7C A;  5CLL B;  3RCP A;  2CY5 A;  4YON A;  2YT1 A;  3X23 A;  3G9W A;  3SUZ A;  1NU2 A;  1SGH A;  1WJ1 A;  2L1C A;  3P7Z A;  4QJ4 B;  3ODX A;  4HHV A;  3HQC A;  1AQC A;  4D6W A;  1WJM A;  2XQN M;  2EJ8 A;  2COC A;  5JP4 A;  5D3X A;  2Z0Q A;  1TJ6 A;  1OY2 A;  2EMS A;  4GOU A;  1FOE A;  3VOQ A;  2DTC A;  3T06 A;  3UZT A;  4EJN A;  3ODO A;  2JP2 A;  3P6A A;  1TXD A;  4A6K A;  2IYB A;  5GOW B;  3SNH A;  3KY9 A;  5I2S A;  5M4Y B;  3U7D A;  1AWE A;  4XWX A;  4DXA B;  2LUL A;  1Y5O A;  3A8P A;  2Z14 A;  2HTH B;  4IAP A;  2Z0P A;  3OAN A;  2I5C A;  4H8S A;  4YL8 A;  1FAO A;  4F7H A;  3PVU A;  2YS3 A;  1GG3 A;  4KHA A;  4HAT B;  2PZ1 A;  2GCJ A;  1U29 A;  3ZDT A;  2IFS A;  2K8E A;  5HE1 A;  2GCL A;  1MIZ B;  2W2W A;  2FJU B;  1V89 A;  2D9Z A;  3QBV B;  1XKE A;  1EVH A;  2YS5 A;  2ELB A;  1B55 A;  4C0A A;  2K2J A;  2NMB A;  2Z59 A;  3V5W A;  1V5U A;  1M7R A;  4DX9 0;  1DDM A;  2YSZ A;  2YT2 A;  3WYF B;  2ROZ B;  3AU5 A;  2Y8F A;  1FHO A;  2DKP A;  1J0W A;  4NSW A;  2NZ8 B;  3AJ4 A;  1ZC3 B;  4KHB B;  4A5K A;  3PP2 A;  2KUQ A;  1UNQ A;  3TCA A;  1W1D A;  4K81 A;  2KIE A;  1M7E A;  1MK7 B;  2CAY A;  2DLW A;  2YF0 A;  3PZD A;  3KSY A;  4OSN A;  4PNK A;  2L2I A;  3KZ1 A;  1EAZ A;  3A98 B;  5D3Y A;  1UNR A;  4L6E A;  3U8Z A;  1ZC4 B;  1WG7 A;  2RRF A;  2J59 M;  1MAI A;  2Z0O A;  4B6H A;  2UZR A;  1XX0 A;  3SV1 A;  3TVV A;  4K2O A;  2P0F A;  3F0W A;  4DIX A;  2K2U A;  1MPH A;  3LJU X;  3DCX A;  2P8V A;  1WGQ A;  2D9W A;  2DA0 A;  1P6S A;  5D3V A;  2Y7B A;  1X05 A;  1BTN A;  1N3H A;  5FI0 A;  2GJY A;  4NY0 A;  2LYD A;  1QC6 A;  1Y19 B;  5KQ4 A;  1E5W A;  2AEH A;  4IOY X;  4QJ3 B;  3WA0 A;  1UNP A;  1UEF A; 
#chains in the Genus database with same CATH homology
 1W1G A;  2LOZ A;  4WJ7 A;  1J19 A;  2N0Y A;  3TW1 A;  2EC1 A;  3SO6 A;  1U5D A;  4DX8 A;  2YVC A;  4F7U P;  2QKM A;  1UPR A;  2UVM A;  3M1I B;  5J3Y A;  3F5R A;  5C16 A;  1U27 A;  1IRS A;  3ODW A;  5DHF B;  4A6H A;  3QWM A;  2R09 A;  4CYE A;  3PVL A;  3KRW A;  2MWN B;  1EF1 A;  2OTX A;  1RJ2 A;  3ML4 A;  2COD A;  4K2P A;  4ZRI A;  2KCJ A;  2I1K A;  2J0M A;  2M14 A;  3SYX A;  4KHO A;  2RGN B;  1XOD A;  5C79 A;  1WI1 A;  1U5E A;  1GC6 A;  4DBB A;  1RRP B;  5JHG A;  3ZVR A;  3MPX A;  1X86 A;  2RNR B;  5J3Q A;  3PEG A;  5DIF B;  4MK0 A;  2W2X C;  1OQN A;  5HE0 A;  1BAK A;  4Y94 A;  1PFJ A;  4HDO A;  3FEH A;  2LKO A;  4CHJ A;  4KVG B;  5JHH A;  1X1F A;  2D10 A;  4HB2 B;  3VIA A;  2J0J A;  5DHA B;  2RVB B;  2DHK A;  5DI9 B;  2AL6 A;  2KGX B;  5EFX A;  2MDX A;  4HAV B;  5J3T A;  2GS0 A;  1P3R A;  1H10 A;  2MKR A;  1UPQ A;  1W1H A;  3ULB A;  1EGX A;  1V61 A;  4HAU B;  4GPT B;  2ZPY A;  1U5F A;  2VRW B;  1I7A A;  4HB3 B;  3BIN A;  2YS1 A;  1V88 A;  4EMO A;  1NTY A;  3QIJ A;  1FB8 A;  2DHJ A;  1K5D B;  2H7D A;  5FI1 A;  1H4R A;  2X18 A;  3DXC A;  2ROV A;  2D9X A;  5C5B B;  1X1G A;  3DXE A;  4IFS A;  2G35 A;  3CIK A;  2UZS A;  4HAW B;  2K00 A;  1Q67 A;  1KI1 B;  1PMS A;  1ISN A;  2N23 A;  4GXB A;  1I2H A;  2OQB A;  2V76 A;  3A8Q A;  1DRO A;  2CRF A;  4EKU A;  4K17 A;  2DYQ A;  1TQZ A;  4GMX B;  1FGY A;  2YT0 A;  3O96 A;  2COA A;  5KQ1 A;  1BWN A;  4BBK A;  2BCJ A;  2I1J A;  2RLO A;  1X11 A;  2FJL A;  3D8F A;  1Z87 A;  3NSU A;  5LON B;  1NTV A;  2J0K A;  2P0H A;  4GN1 A;  4HAZ B;  1GC7 A;  2DN6 A;  2COF A;  4F7G A;  2P0D A;  2DFK A;  2M38 A;  3HW2 B;  3ULC A;  4GZU A;  2DYN A;  4MT7 A;  2D9V A;  3PVW A;  1DDV A;  3PG7 A;  4Z2N A;  4HDQ A;  2D2Q A;  5C6R A;  2DKQ A;  4PQ0 A;  4MY6 A;  4KAX B;  2ELA A;  2D11 A;  4A6F B;  2Y8G A;  1V5M A;  2W2X D;  5HE3 A;  1ZSQ A;  3TO1 A;  1XCG A;  1BTK A;  3PSC A;  1DYN A;  1MK9 B;  2DX1 A;  5KCV A;  3FM8 C;  4Z2M B;  1WVH A;  1FGZ A;  4WSF A;  4A6F A;  4HAX B;  1MKE A;  1NI2 A;  2Q13 A;  2E2X A;  1P5T A;  1KZ7 A;  1U5G A;  1ZVR A;  3BJI A;  2I5F A;  2LOX A;  4CHM A;  2D4Q A;  4TYZ A;  1FHW A;  1ZM0 A;  4ZRK A;  2RSG A;  3KRX A;  1XD4 A;  4TKN A;  1OMW A;  2CY4 A;  1SHC A;  1K5G B;  1LW3 A;  2EMT A;  4HB0 B;  1LB1 A;  2YRY A;  2R0D A;  3AU4 A;  3HK0 A;  3CXB B;  1PLS A;  5D3W A;  1MIX A;  4GMV A;  2ADZ A;  3TFM A;  2DX5 A;  1WGU A;  1DBH A;  2D9Y A;  2HE7 A;  2VSZ A;  5L81 A;  1XR0 B;  4WVF B;  5D27 A;  4D0N B;  3MDB C;  1V5P A;  2H7E A;  1KZG A;  2DHI A;  3D8D A;  3DXD A;  4P7I A;  2QKL A;  2LG1 A;  5LOP B;  2MFQ A;  3IVF A;  2KUP A;  5HE2 A;  5CLQ B;  1QQG A;  2RUK B;  5JLJ B;  1FHX A;  1U2B A;  5C5B A;  4HAY B;  5DH9 B;  3GYO A;  3D8E A;  4HB4 B;  3GYP A;  4ZRJ A;  3FSS A;  1DDW A;  2VKI A;  3N7C A;  5CLL B;  3RCP A;  2CY5 A;  4YON A;  2YT1 A;  3X23 A;  3G9W A;  3SUZ A;  1NU2 A;  1SGH A;  1WJ1 A;  2L1C A;  3P7Z A;  3ODX A;  4HHV A;  3HQC A;  1AQC A;  1WJM A;  2XQN M;  2EJ8 A;  2COC A;  5JP4 A;  5D3X A;  2Z0Q A;  1TJ6 A;  1OY2 A;  2EMS A;  1FOE A;  3VOQ A;  2DTC A;  3T06 A;  3UZT A;  4EJN A;  3ODO A;  2JP2 A;  3P6A A;  1TXD A;  4A6K A;  2IYB A;  5GOW B;  3SNH A;  3KY9 A;  3U7D A;  1AWE A;  4XWX A;  4DXA B;  2LUL A;  1Y5O A;  3A8P A;  2HTH B;  4IAP A;  2Z0P A;  3OAN A;  2I5C A;  4H8S A;  4YL8 A;  1FAO A;  4F7H A;  3PVU A;  2YS3 A;  1GG3 A;  4KHA A;  4HAT B;  2PZ1 A;  2GCJ A;  1U29 A;  3ZDT A;  2IFS A;  5HE1 A;  2GCL A;  1MIZ B;  2W2W A;  1V89 A;  2D9Z A;  3QBV B;  1XKE A;  1EVH A;  2YS5 A;  2ELB A;  1B55 A;  4C0A A;  2K2J A;  2NMB A;  3V5W A;  1V5U A;  1M7R A;  4DX9 0;  1DDM A;  2YSZ A;  3WYF B;  2ROZ B;  3AU5 A;  2Y8F A;  1FHO A;  2DKP A;  1J0W A;  4NSW A;  2NZ8 B;  3AJ4 A;  1ZC3 B;  4KHB B;  4A5K A;  3PP2 A;  1UNQ A;  3TCA A;  1W1D A;  4K81 A;  1M7E A;  1MK7 B;  2CAY A;  2DLW A;  2YF0 A;  3PZD A;  3KSY A;  4PNK A;  2L2I A;  3KZ1 A;  1EAZ A;  3A98 B;  5D3Y A;  1UNR A;  4L6E A;  3U8Z A;  1ZC4 B;  1WG7 A;  2J59 M;  1MAI A;  2Z0O A;  4B6H A;  2UZR A;  1XX0 A;  3SV1 A;  3TVV A;  4K2O A;  2P0F A;  3F0W A;  2K2U A;  1MPH A;  3LJU X;  2P8V A;  1WGQ A;  2D9W A;  2DA0 A;  1P6S A;  5D3V A;  2Y7B A;  1X05 A;  1BTN A;  1N3H A;  5FI0 A;  2GJY A;  4NY0 A;  2LYD A;  1QC6 A;  1Y19 B;  5KQ4 A;  1E5W A;  2AEH A;  4IOY X;  3WA0 A;  1UNP A;  1UEF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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