1BTKA

Ph domain and btk motif from bruton's tyrosine kinase mutant r28c
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
169
structure length
160
Chain Sequence
AAVILESIFLKRSQQKKKTSPLNFKKCLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILEN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemia.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords BRUTON'S TYROSINE KINASE
total genus 33
structure length 160
sequence length 169
chains with identical sequence B
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 1997-07-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF00779 BTK BTK motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1btkA00
1WGQA 2DHKA 3PEGA 1XX0A 5L81A 1W1HA 2L2IA 1Q67A 2D9YA 2MDXA 1X1FA 4HAZB 4Y94A 1FAOA 3CIKA 3A8QA 4PNKA 3QBVB 5KQ1A 2QKMA 4D0NB 2ROVA 1K5GB 1V89A 1QQGA 3ZDTA 1SGHA 3ML4A 2DX5A 2DX1A 1P5TA 3OANA 2RNRB 1B55A 1GC6A 1RJ2A 2ROZB 4KHAA 2Y7BA 1BTKA 2D2QA 3PSCA 4HB3B 1N3HA 1NU2A 2EC1A 1XR0B 4EJNA 1MK9B 3TO1A 2UVMA 1ISNA 1WJMA 3CXBB 1P6SA 3PVWA 2FJLA 4GXBA 1M7EA 3GYOA 5HE3A 2N0YA 3AJ4A 1UEFA 3GYPA 1FB8A 1XCGA 4L6EA 2DA0A 2NMBA 4TKNA 4EKUA 2K00A 2P0FA 1BTNA 2ELAA 2COCA 2CAYA 1P3RA 1Y19B 1UPQA 1NTVA 4WJ7A 3QIJA 4GN1A 5DH9B 4GMXB 5CLLB 2M38A 1SHCA 5JHGA 1U5EA 4NSWA 1I7AA 4YONA 4HHVA 4YL8A 2E2XA 2I5CA 1WJ1A 2G35A 2ELBA 3RCPA 4GMVA 2ZPYA 5DHAB 4K17A 3U7DA 4HAUB 1X05A 2RUKB 1ZVRA 1Z87A 1FOEA 2M14A 3F0WA 1KZ7A 1RRPB 4GZUA 4MY6A 3U8ZA 4A6KA 1PFJA 2VRWB 4PQ0A 4F7HA 2AEHA 2PZ1A 1WI1A 2IYBA 2DLWA 3SNHA 5DI9B 4HDQA 3TW1A 1UPRA 1DROA 3D8FA 4Z2NA 1FHWA 5D3XA 3D8EA 5HE1A 2OTXA 2EMSA 1BAKA 2Y8GA 4B6HA 5JHHA 2RSGA 3KRWA 2DYQA 2LG1A 2LYDA 3WYFB 4KAXB 1QC6A 2L1CA 1EGXA 1U27A 3SUZA 4ZRIA 3M1IB 1KI1B 2CODA 4GPTB 2YS5A 2W2XC 1DDMA 3SO6A 1EAZA 1J19A 1FHOA 5KQ4A 2LOZA 2I5FA 4HATB 4Z2MB 2OQBA 1U5DA 4A6HA 1E5WA 2MKRA 3ODWA 3HK0A 1Y5OA 3WA0A 1U5GA 2H7DA 4CHMA 2YVCA 2HE7A 1XD4A 1FHXA 4F7UP 2D10A 2DHJA 3LJUX 5J3YA 3KRXA 3ODOA 1AWEA 3SYXA 5HE0A 2R0DA 1W1DA 4K2PA 2ADZA 5J3TA 2NZ8B 5KCVA 1MIXA 1DYNA 1K5DB 1WGUA 2D11A 2HTHB 4A6FB 4HAVB 4XWXA 1MKEA 4NY0A 5J3QA 5DHFB 2CY5A 5C6RA 4K81A 4HDOA 3KSYA 1FGYA 3V5WA 1MK7B 1X11A 2XQNM 4A6FA 4WSFA 4F7GA 1V5UA 1IRSA 2KUPA 2W2WA 2CRFA 4HAYB 1H10A 2K2JA 2GCLA 3QWMA 2Z0OA 3X23A 2YT0A 2D4QA 4EMOA 1OY2A 1OQNA 3BINA 3IVFA 2I1KA 2X18A 3TVVA 3PZDA 2D9WA 4TYZA 3F5RA 1V5PA 2BCJA 5LOPB 3DXDA 1DDWA 2GS0A 2YS3A 3MDBC 1TXDA 4WVFB 5D3WA 2DTCA 1EF1A 1WVHA 2D9ZA 2Z0PA 2Y8FA 5C79A 2H7EA 2QKLA 3FEHA 1NTYA 2DN6A 1M7RA 2RGNB 1EVHA 3N7CA 3KZ1A 3D8DA 4KHOA 4KVGB 1X86A 4DX90 2YT1A 2V76A 1NI2A 5C16A 3DXCA 2LULA 2J59M 3A8PA 2R09A 4IOYX 3TCAA 3MPXA 1DDVA 2MFQA 4MT7A 1PMSA 1AQCA 1ZM0A 3SV1A 4HAXB 4HB2B 1TQZA 2Z0QA 2COFA 4C0AA 3FM8C 4DXAB 1XODA 3ULCA 4DX8A 3ODXA 1UNRA 1WG7A 3DXEA 3P6AA 3PG7A 1PLSA 3A98B 2DYNA 2RVBB 2IFSA 2MWNB 4BBKA 2YRYA 5HE2A 5EFXA 1ZSQA 5C5BB 2VSZA 2RLOA 1J0WA 2K2UA 1U2BA 1V88A 2DFKA 3ULBA 1MAIA 4DBBA 1MIZB 1BWNA 2UZRA 5JP4A 4IAPA 2YS1A 5GOWB 5C5BA 3VIAA 2YSZA 4K2OA 5FI0A 1GG3A 1UNQA 4CHJA 4MK0A 4ZRKA 2P0HA 3PVUA 5DIFB 1DBHA 2Q13A 1OMWA 2W2XD 4HAWB 4ZRJA 2GCJA 2COAA 2N23A 3BJIA 4CYEA 1LW3A 2VKIA 4IFSA 2JP2A 1I2HA 2D9XA 3O96A 3VOQA 5D27A 2J0MA 1FGZA 1TJ6A 3UZTA 2LKOA 3HW2B 1V5MA 2D9VA 5JLJB 2KGXB 4H8SA 5LONB 5D3VA 2EJ8A 3HQCA 5D3YA 1XKEA 3T06A 1U5FA 4HB4B 4HB0B 2LOXA 2GJYA 2I1JA 4A5KA 4P7IA 3AU4A 2UZSA 2EMTA 1W1GA 1ZC3B 3PVLA 2P0DA 3P7ZA 1V61A 5CLQB 2YF0A 5FI1A 1LB1A 1GC7A 2P8VA 1H4RA 3ZVRA 1U29A 2KCJA 1ZC4B 1MPHA 3G9WA 2DHIA 3PP2A 1X1GA 1KZGA 2DKPA 2AL6A 2J0KA 3FSSA 3AU5A 4KHBB 3NSUA 1UNPA 2J0JA 2CY4A 3KY9A 3TFMA 2DKQA
chains in the Genus database with same CATH superfamily
1WGQA 2DHKA 3PEGA 1XX0A 5L81A 1W1HA 2L2IA 4KHBA 1Q67A 2D9YA 2MDXA 1X1FA 4HAZB 4Y94A 1FAOA 3CIKA 3A8QA 4CSQA 2KR0A 4PNKA 3QBVB 5KQ1A 2QKMA 4D0NB 2ROVA 1K5GB 1V89A 1QQGA 3ZDTA 1SGHA 3ML4A 2DX5A 2DX1A 1P5TA 3OANA 2RNRB 1B55A 1GC6A 1RJ2A 2ROZB 4KHAA 2Y7BA 1BTKA 2D2QA 3PSCA 4HB3B 1N3HA 1NU2A 2EC1A 1XR0B 4HSIA 4EJNA 1MK9B 3TO1A 3U12A 2UVMA 1ISNA 1WJMA 3CXBB 1P6SA 3PVWA 2FJLA 4GXBA 1M7EA 3GYOA 5HE3A 2N0YA 3AJ4A 1UEFA 3NWFA 3GYPA 1FB8A 1XCGA 4L6EA 2DA0A 2NMBA 4TKNA 4EKUA 2K00A 2P0FA 1BTNA 2ELAA 2COCA 2CAYA 1P3RA 1Y19B 1UPQA 1NTVA 4WJ7A 4GOUA 3QIJA 4GN1A 5DH9B 4GMXB 5CLLB 2M38A 1SHCA 5JHGA 1U5EA 4NSWA 1I7AA 4YONA 4HHVA 4YL8A 2E2XA 2I5CA 1WJ1A 4L1RA 2G35A 2ELBA 3RCPA 4GMVA 3DCXA 2ZPYA 5DHAB 4K17A 3U7DA 4HAUB 1X05A 2RUKB 1ZVRA 1Z87A 1FOEA 2M14A 3F0WA 1KZ7A 1RRPB 4GZUA 4MY6A 4D6WA 3U8ZA 4A6KA 1PFJA 2VRWB 4PQ0A 4F7HA 2AEHA 2PZ1A 1WI1A 2IYBA 2DLWA 3SNHA 5DI9B 4HDQA 3TW1A 1UPRA 1DROA 3D8FA 4Z2NA 1FHWA 5D3XA 2YT2A 4DIXA 3D8EA 5HE1A 2OTXA 2EMSA 1BAKA 2Y8GA 4B6HA 5JHHA 1ZYIA 2RSGA 3KRWA 2DYQA 2LG1A 2LYDA 3WYFB 4KAXB 1QC6A 2L1CA 1EGXA 1U27A 3SUZA 4ZRIA 3M1IB 1KI1B 2CODA 4GPTB 2YS5A 2W2XC 1DDMA 3SO6A 1EAZA 1J19A 1FHOA 5KQ4A 2LOZA 2I5FA 4HATB 4Z2MB 2OQBA 1U5DA 3A58A 4A6HA 1E5WA 2MKRA 3ODWA 3HK0A 1Y5OA 3WA0A 1U5GA 2H7DA 4CHMA 2YVCA 2HE7A 1XD4A 1FHXA 4F7UP 2D10A 2DHJA 3LJUX 5J3YA 3KRXA 3ODOA 1AWEA 3SYXA 5IRSA 5HE0A 2R0DA 1W1DA 4K2PA 2ADZA 5J3TA 2NZ8B 5KCVA 1MIXA 1DYNA 1K5DB 1WGUA 2D11A 2HTHB 4A6FB 4HAVB 4XWXA 3HSAA 1MKEA 4NY0A 4QXAB 5J3QA 4QJ5B 5DHFB 2CY5A 5C6RA 4K81A 3B77A 4HDOA 3KSYA 1FGYA 3V5WA 4QJ3B 1MK7B 1X11A 2XQNM 4A6FA 4WSFA 4F7GA 1V5UA 1IRSA 2KUPA 2W2WA 2CRFA 4HAYB 1H10A 2K2JA 2GCLA 3QWMA 2GUMA 2Z0OA 3X23A 2YT0A 2K49A 2D4QA 2Z59A 4EMOA 1OY2A 1OQNA 3BINA 3IVFA 2I1KA 2X18A 4OT1A 3TVVA 3PZDA 2D9WA 4TYZA 3F5RA 1V5PA 2BCJA 5LOPB 3DXDA 1DDWA 2GS0A 2YS3A 3MDBC 1TXDA 4WVFB 5D3WA 2DTCA 1EF1A 1WVHA 2D9ZA 2Z13A 2Z0PA 2Y8FA 5C79A 2H7EA 2QKLA 3FEHA 1NTYA 2DN6A 1M7RA 2RGNB 1EVHA 3N7CA 3KZ1A 3D8DA 4KHOA 4KVGB 1X86A 2K8EA 4DX90 2YT1A 2V76A 1NI2A 2KUQA 5C16A 3DXCA 2LULA 2KIGA 2J59M 3A8PA 2R09A 4IOYX 3TCAA 3MPXA 1DDVA 2MFQA 4MT7A 1PMSA 2Z14A 1AQCA 1ZM0A 3SV1A 4HAXB 4HB2B 1TQZA 2Z0QA 2COFA 4C0AA 3FM8C 4GNKB 4DXAB 1XODA 3ULCA 4DX8A 3ODXA 1UNRA 1WG7A 3DXEA 3P6AA 3PG7A 1PLSA 3A98B 2DYNA 2RVBB 2IFSA 2MWNB 4BBKA 2YRYA 5HE2A 2Z4DA 5EFXA 1T77A 2R2YA 1ZSQA 5C5BB 2VSZA 2RLOA 1J0WA 2K2UA 1U2BA 1V88A 2DFKA 3ULBA 1MAIA 4DBBA 1MIZB 1BWNA 2UZRA 5JP4A 2NBVA 4IAPA 2YS1A 5GOWB 5C5BA 3VIAA 2YSZA 4K2OA 5FI0A 4OSNA 1GG3A 1UNQA 4CHJA 4MK0A 4ZRKA 2P0HA 3PVUA 5DIFB 1DBHA 2Q13A 1OMWA 2W2XD 4HAWB 4ZRJA 2GCJA 2COAA 2N23A 3BJIA 4CYEA 1LW3A 2VKIA 4IFSA 2JP2A 1MI1A 1I2HA 2D9XA 3O96A 3VOQA 5D27A 2FJUB 2J0MA 1FGZA 1TJ6A 3UZTA 2LKOA 3HW2B 3HIEA 1V5MA 2D9VA 5JLJB 2KGXB 5M4YB 4H8SA 5LONB 5D3VA 2EJ8A 3HQCA 5D3YA 1XKEA 3T06A 1U5FA 2KIEA 4HB4B 4QJ4B 4HB0B 2LOXA 2GJYA 2I1JA 4A5KA 4P7IA 5LG4B 3NWAA 2ZKMX 3AU4A 2UZSA 2EMTA 1W1GA 1ZC3B 3PVLA 2P0DA 3NW8A 3OHMB 3P7ZA 5I2SA 1V61A 5CLQB 2YF0A 5FI1A 1LB1A 1GC7A 2P8VA 1H4RA 3ZVRA 1U29A 2KCJA 1ZC4B 1MPHA 3G9WA 2DHIA 3PP2A 1X1GA 1KZGA 2DKPA 2AL6A 2J0KA 3FSSA 3AU5A 2RRFA 4KHBB 3NSUA 1UNPA 2J0JA 2CY4A 3NWDA 3KY9A 3TFMA 3FVCA 5I2MA 2DKQA
chains in the Genus database with same CATH topology
1WGQA 2DHKA 3PEGA 1XX0A 5L81A 1W1HA 2L2IA 1Q67A 2D9YA 2MDXA 1X1FA 4HAZB 4Y94A 1FAOA 3CIKA 3A8QA 4PNKA 3QBVB 5KQ1A 2QKMA 4D0NB 2ROVA 1K5GB 1V89A 1QQGA 3ZDTA 1SGHA 3ML4A 2DX5A 2DX1A 1P5TA 3OANA 2RNRB 1B55A 1GC6A 1RJ2A 2ROZB 4KHAA 2Y7BA 1BTKA 2D2QA 3PSCA 4HB3B 1N3HA 1NU2A 2EC1A 1XR0B 4EJNA 1MK9B 3TO1A 2UVMA 1ISNA 1WJMA 3CXBB 1P6SA 3PVWA 2FJLA 4GXBA 1M7EA 3GYOA 5HE3A 2N0YA 3AJ4A 1UEFA 3GYPA 1FB8A 1XCGA 4L6EA 2DA0A 2NMBA 4TKNA 4EKUA 2K00A 2P0FA 1BTNA 2ELAA 2COCA 2CAYA 1P3RA 1Y19B 1UPQA 1NTVA 4WJ7A 3QIJA 4GN1A 5DH9B 4GMXB 5CLLB 2M38A 1SHCA 5JHGA 1U5EA 4NSWA 1I7AA 4YONA 4HHVA 4YL8A 2E2XA 2I5CA 1WJ1A 2G35A 2ELBA 3RCPA 4GMVA 2ZPYA 5DHAB 4K17A 3U7DA 4HAUB 1X05A 2RUKB 1ZVRA 1Z87A 1FOEA 2M14A 3F0WA 1KZ7A 1RRPB 4GZUA 4MY6A 3U8ZA 4A6KA 1PFJA 2VRWB 4PQ0A 4F7HA 2AEHA 2PZ1A 1WI1A 2IYBA 2DLWA 3SNHA 5DI9B 4HDQA 3TW1A 1UPRA 1DROA 3D8FA 4Z2NA 1FHWA 5D3XA 3D8EA 5HE1A 2OTXA 2EMSA 1BAKA 2Y8GA 4B6HA 5JHHA 2RSGA 3KRWA 2DYQA 2LG1A 2LYDA 3WYFB 4KAXB 1QC6A 2L1CA 1EGXA 1U27A 3SUZA 4ZRIA 3M1IB 1KI1B 2CODA 4GPTB 2YS5A 2W2XC 1DDMA 3SO6A 1EAZA 1J19A 1FHOA 5KQ4A 2LOZA 2I5FA 4HATB 4Z2MB 2OQBA 1U5DA 4A6HA 1E5WA 2MKRA 3ODWA 3HK0A 1Y5OA 3WA0A 1U5GA 2H7DA 4CHMA 2YVCA 2HE7A 1XD4A 1FHXA 4F7UP 2D10A 2DHJA 3LJUX 5J3YA 3KRXA 3ODOA 1AWEA 3SYXA 5HE0A 2R0DA 1W1DA 4K2PA 2ADZA 5J3TA 2NZ8B 5KCVA 1MIXA 1DYNA 1K5DB 1WGUA 2D11A 2HTHB 4A6FB 4HAVB 4XWXA 1MKEA 4NY0A 5J3QA 5DHFB 2CY5A 5C6RA 4K81A 4HDOA 3KSYA 1FGYA 3V5WA 1MK7B 1X11A 2XQNM 4A6FA 4WSFA 4F7GA 1V5UA 1IRSA 2KUPA 2W2WA 2CRFA 4HAYB 1H10A 2K2JA 2GCLA 3QWMA 2Z0OA 3X23A 2YT0A 2D4QA 4EMOA 1OY2A 1OQNA 3BINA 3IVFA 2I1KA 2X18A 3TVVA 3PZDA 2D9WA 4TYZA 3F5RA 1V5PA 2BCJA 5LOPB 3DXDA 1DDWA 2GS0A 2YS3A 3MDBC 1TXDA 4WVFB 5D3WA 2DTCA 1EF1A 1WVHA 2D9ZA 2Z0PA 2Y8FA 5C79A 2H7EA 2QKLA 3FEHA 1NTYA 2DN6A 1M7RA 2RGNB 1EVHA 3N7CA 3KZ1A 3D8DA 4KHOA 4KVGB 1X86A 4DX90 2YT1A 2V76A 1NI2A 5C16A 3DXCA 2LULA 2J59M 3A8PA 2R09A 4IOYX 3TCAA 3MPXA 1DDVA 2MFQA 4MT7A 1PMSA 1AQCA 1ZM0A 3SV1A 4HAXB 4HB2B 1TQZA 2Z0QA 2COFA 4C0AA 3FM8C 4DXAB 1XODA 3ULCA 4DX8A 3ODXA 1UNRA 1WG7A 3DXEA 3P6AA 3PG7A 1PLSA 3A98B 2DYNA 2RVBB 2IFSA 2MWNB 4BBKA 2YRYA 5HE2A 5EFXA 1ZSQA 5C5BB 2VSZA 2RLOA 1J0WA 2K2UA 1U2BA 1V88A 2DFKA 3ULBA 1MAIA 4DBBA 1MIZB 1BWNA 2UZRA 5JP4A 4IAPA 2YS1A 5GOWB 5C5BA 3VIAA 2YSZA 4K2OA 5FI0A 1GG3A 1UNQA 4CHJA 4MK0A 4ZRKA 2P0HA 3PVUA 5DIFB 1DBHA 2Q13A 1OMWA 2W2XD 4HAWB 4ZRJA 2GCJA 2COAA 2N23A 3BJIA 4CYEA 1LW3A 2VKIA 4IFSA 2JP2A 1I2HA 2D9XA 3O96A 3VOQA 5D27A 2J0MA 1FGZA 1TJ6A 3UZTA 2LKOA 3HW2B 1V5MA 2D9VA 5JLJB 2KGXB 4H8SA 5LONB 5D3VA 2EJ8A 3HQCA 5D3YA 1XKEA 3T06A 1U5FA 4HB4B 4HB0B 2LOXA 2GJYA 2I1JA 4A5KA 4P7IA 3AU4A 2UZSA 2EMTA 1W1GA 1ZC3B 3PVLA 2P0DA 3P7ZA 1V61A 5CLQB 2YF0A 5FI1A 1LB1A 1GC7A 2P8VA 1H4RA 3ZVRA 1U29A 2KCJA 1ZC4B 1MPHA 3G9WA 2DHIA 3PP2A 1X1GA 1KZGA 2DKPA 2AL6A 2J0KA 3FSSA 3AU5A 4KHBB 3NSUA 1UNPA 2J0JA 2CY4A 3KY9A 3TFMA 2DKQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WGQ A;  2DHK A;  3PEG A;  1XX0 A;  5L81 A;  1W1H A;  2L2I A;  1Q67 A;  2D9Y A;  2MDX A;  1X1F A;  4HAZ B;  4Y94 A;  1FAO A;  3CIK A;  3A8Q A;  4PNK A;  3QBV B;  5KQ1 A;  2QKM A;  4D0N B;  2ROV A;  1K5G B;  1V89 A;  1QQG A;  3ZDT A;  1SGH A;  3ML4 A;  2DX5 A;  2DX1 A;  1P5T A;  3OAN A;  2RNR B;  1B55 A;  1GC6 A;  1RJ2 A;  2ROZ B;  4KHA A;  2Y7B A;  1BTK A;  2D2Q A;  3PSC A;  4HB3 B;  1N3H A;  1NU2 A;  2EC1 A;  1XR0 B;  4EJN A;  1MK9 B;  3TO1 A;  2UVM A;  1ISN A;  1WJM A;  3CXB B;  1P6S A;  3PVW A;  2FJL A;  4GXB A;  1M7E A;  3GYO A;  5HE3 A;  2N0Y A;  3AJ4 A;  1UEF A;  3GYP A;  1FB8 A;  1XCG A;  4L6E A;  2DA0 A;  2NMB A;  4TKN A;  4EKU A;  2K00 A;  2P0F A;  1BTN A;  2ELA A;  2COC A;  2CAY A;  1P3R A;  1Y19 B;  1UPQ A;  1NTV A;  4WJ7 A;  3QIJ A;  4GN1 A;  5DH9 B;  4GMX B;  5CLL B;  2M38 A;  1SHC A;  5JHG A;  1U5E A;  4NSW A;  1I7A A;  4YON A;  4HHV A;  4YL8 A;  2E2X A;  2I5C A;  1WJ1 A;  2G35 A;  2ELB A;  3RCP A;  4GMV A;  2ZPY A;  5DHA B;  4K17 A;  3U7D A;  4HAU B;  1X05 A;  2RUK B;  1ZVR A;  1Z87 A;  1FOE A;  2M14 A;  3F0W A;  1KZ7 A;  1RRP B;  4GZU A;  4MY6 A;  3U8Z A;  4A6K A;  1PFJ A;  2VRW B;  4PQ0 A;  4F7H A;  2AEH A;  2PZ1 A;  1WI1 A;  2IYB A;  2DLW A;  3SNH A;  5DI9 B;  4HDQ A;  3TW1 A;  1UPR A;  1DRO A;  3D8F A;  4Z2N A;  1FHW A;  5D3X A;  3D8E A;  5HE1 A;  2OTX A;  2EMS A;  1BAK A;  2Y8G A;  4B6H A;  5JHH A;  2RSG A;  3KRW A;  2DYQ A;  2LG1 A;  2LYD A;  3WYF B;  4KAX B;  1QC6 A;  2L1C A;  1EGX A;  1U27 A;  3SUZ A;  4ZRI A;  3M1I B;  1KI1 B;  2COD A;  4GPT B;  2YS5 A;  2W2X C;  1DDM A;  3SO6 A;  1EAZ A;  1J19 A;  1FHO A;  5KQ4 A;  2LOZ A;  2I5F A;  4HAT B;  4Z2M B;  2OQB A;  1U5D A;  4A6H A;  1E5W A;  2MKR A;  3ODW A;  3HK0 A;  1Y5O A;  3WA0 A;  1U5G A;  2H7D A;  4CHM A;  2YVC A;  2HE7 A;  1XD4 A;  1FHX A;  4F7U P;  2D10 A;  2DHJ A;  3LJU X;  5J3Y A;  3KRX A;  3ODO A;  1AWE A;  3SYX A;  5HE0 A;  2R0D A;  1W1D A;  4K2P A;  2ADZ A;  5J3T A;  2NZ8 B;  5KCV A;  1MIX A;  1DYN A;  1K5D B;  1WGU A;  2D11 A;  2HTH B;  4A6F B;  4HAV B;  4XWX A;  1MKE A;  4NY0 A;  5J3Q A;  5DHF B;  2CY5 A;  5C6R A;  4K81 A;  4HDO A;  3KSY A;  1FGY A;  3V5W A;  1MK7 B;  1X11 A;  2XQN M;  4A6F A;  4WSF A;  4F7G A;  1V5U A;  1IRS A;  2KUP A;  2W2W A;  2CRF A;  4HAY B;  1H10 A;  2K2J A;  2GCL A;  3QWM A;  2Z0O A;  3X23 A;  2YT0 A;  2D4Q A;  4EMO A;  1OY2 A;  1OQN A;  3BIN A;  3IVF A;  2I1K A;  2X18 A;  3TVV A;  3PZD A;  2D9W A;  4TYZ A;  3F5R A;  1V5P A;  2BCJ A;  5LOP B;  3DXD A;  1DDW A;  2GS0 A;  2YS3 A;  3MDB C;  1TXD A;  4WVF B;  5D3W A;  2DTC A;  1EF1 A;  1WVH A;  2D9Z A;  2Z0P A;  2Y8F A;  5C79 A;  2H7E A;  2QKL A;  3FEH A;  1NTY A;  2DN6 A;  1M7R A;  2RGN B;  1EVH A;  3N7C A;  3KZ1 A;  3D8D A;  4KHO A;  4KVG B;  1X86 A;  4DX9 0;  2YT1 A;  2V76 A;  1NI2 A;  5C16 A;  3DXC A;  2LUL A;  2J59 M;  3A8P A;  2R09 A;  4IOY X;  3TCA A;  3MPX A;  1DDV A;  2MFQ A;  4MT7 A;  1PMS A;  1AQC A;  1ZM0 A;  3SV1 A;  4HAX B;  4HB2 B;  1TQZ A;  2Z0Q A;  2COF A;  4C0A A;  3FM8 C;  4DXA B;  1XOD A;  3ULC A;  4DX8 A;  3ODX A;  1UNR A;  1WG7 A;  3DXE A;  3P6A A;  3PG7 A;  1PLS A;  3A98 B;  2DYN A;  2RVB B;  2IFS A;  2MWN B;  4BBK A;  2YRY A;  5HE2 A;  5EFX A;  1ZSQ A;  5C5B B;  2VSZ A;  2RLO A;  1J0W A;  2K2U A;  1U2B A;  1V88 A;  2DFK A;  3ULB A;  1MAI A;  4DBB A;  1MIZ B;  1BWN A;  2UZR A;  5JP4 A;  4IAP A;  2YS1 A;  5GOW B;  5C5B A;  3VIA A;  2YSZ A;  4K2O A;  5FI0 A;  1GG3 A;  1UNQ A;  4CHJ A;  4MK0 A;  4ZRK A;  2P0H A;  3PVU A;  5DIF B;  1DBH A;  2Q13 A;  1OMW A;  2W2X D;  4HAW B;  4ZRJ A;  2GCJ A;  2COA A;  2N23 A;  3BJI A;  4CYE A;  1LW3 A;  2VKI A;  4IFS A;  2JP2 A;  1I2H A;  2D9X A;  3O96 A;  3VOQ A;  5D27 A;  2J0M A;  1FGZ A;  1TJ6 A;  3UZT A;  2LKO A;  3HW2 B;  1V5M A;  2D9V A;  5JLJ B;  2KGX B;  4H8S A;  5LON B;  5D3V A;  2EJ8 A;  3HQC A;  5D3Y A;  1XKE A;  3T06 A;  1U5F A;  4HB4 B;  4HB0 B;  2LOX A;  2GJY A;  2I1J A;  4A5K A;  4P7I A;  3AU4 A;  2UZS A;  2EMT A;  1W1G A;  1ZC3 B;  3PVL A;  2P0D A;  3P7Z A;  1V61 A;  5CLQ B;  2YF0 A;  5FI1 A;  1LB1 A;  1GC7 A;  2P8V A;  1H4R A;  3ZVR A;  1U29 A;  2KCJ A;  1ZC4 B;  1MPH A;  3G9W A;  2DHI A;  3PP2 A;  1X1G A;  1KZG A;  2DKP A;  2AL6 A;  2J0K A;  3FSS A;  3AU5 A;  4KHB B;  3NSU A;  1UNP A;  2J0J A;  2CY4 A;  3KY9 A;  3TFM A;  2DKQ A; 
#chains in the Genus database with same CATH topology
 1WGQ A;  2DHK A;  3PEG A;  1XX0 A;  5L81 A;  1W1H A;  2L2I A;  4KHB A;  1Q67 A;  2D9Y A;  2MDX A;  1X1F A;  4HAZ B;  4Y94 A;  1FAO A;  3CIK A;  3A8Q A;  4CSQ A;  2KR0 A;  4PNK A;  3QBV B;  5KQ1 A;  2QKM A;  4D0N B;  2ROV A;  1K5G B;  1V89 A;  1QQG A;  3ZDT A;  1SGH A;  3ML4 A;  2DX5 A;  2DX1 A;  1P5T A;  3OAN A;  2RNR B;  1B55 A;  1GC6 A;  1RJ2 A;  2ROZ B;  4KHA A;  2Y7B A;  1BTK A;  2D2Q A;  3PSC A;  4HB3 B;  1N3H A;  1NU2 A;  2EC1 A;  1XR0 B;  4HSI A;  4EJN A;  1MK9 B;  3TO1 A;  3U12 A;  2UVM A;  1ISN A;  1WJM A;  3CXB B;  1P6S A;  3PVW A;  2FJL A;  4GXB A;  1M7E A;  3GYO A;  5HE3 A;  2N0Y A;  3AJ4 A;  1UEF A;  3NWF A;  3GYP A;  1FB8 A;  1XCG A;  4L6E A;  2DA0 A;  2NMB A;  4TKN A;  4EKU A;  2K00 A;  2P0F A;  1BTN A;  2ELA A;  2COC A;  2CAY A;  1P3R A;  1Y19 B;  1UPQ A;  1NTV A;  4WJ7 A;  4GOU A;  3QIJ A;  4GN1 A;  5DH9 B;  4GMX B;  5CLL B;  2M38 A;  1SHC A;  5JHG A;  1U5E A;  4NSW A;  1I7A A;  4YON A;  4HHV A;  4YL8 A;  2E2X A;  2I5C A;  1WJ1 A;  4L1R A;  2G35 A;  2ELB A;  3RCP A;  4GMV A;  3DCX A;  2ZPY A;  5DHA B;  4K17 A;  3U7D A;  4HAU B;  1X05 A;  2RUK B;  1ZVR A;  1Z87 A;  1FOE A;  2M14 A;  3F0W A;  1KZ7 A;  1RRP B;  4GZU A;  4MY6 A;  4D6W A;  3U8Z A;  4A6K A;  1PFJ A;  2VRW B;  4PQ0 A;  4F7H A;  2AEH A;  2PZ1 A;  1WI1 A;  2IYB A;  2DLW A;  3SNH A;  5DI9 B;  4HDQ A;  3TW1 A;  1UPR A;  1DRO A;  3D8F A;  4Z2N A;  1FHW A;  5D3X A;  2YT2 A;  4DIX A;  3D8E A;  5HE1 A;  2OTX A;  2EMS A;  1BAK A;  2Y8G A;  4B6H A;  5JHH A;  1ZYI A;  2RSG A;  3KRW A;  2DYQ A;  2LG1 A;  2LYD A;  3WYF B;  4KAX B;  1QC6 A;  2L1C A;  1EGX A;  1U27 A;  3SUZ A;  4ZRI A;  3M1I B;  1KI1 B;  2COD A;  4GPT B;  2YS5 A;  2W2X C;  1DDM A;  3SO6 A;  1EAZ A;  1J19 A;  1FHO A;  5KQ4 A;  2LOZ A;  2I5F A;  4HAT B;  4Z2M B;  2OQB A;  1U5D A;  3A58 A;  4A6H A;  1E5W A;  2MKR A;  3ODW A;  3HK0 A;  1Y5O A;  3WA0 A;  1U5G A;  2H7D A;  4CHM A;  2YVC A;  2HE7 A;  1XD4 A;  1FHX A;  4F7U P;  2D10 A;  2DHJ A;  3LJU X;  5J3Y A;  3KRX A;  3ODO A;  1AWE A;  3SYX A;  5IRS A;  5HE0 A;  2R0D A;  1W1D A;  4K2P A;  2ADZ A;  5J3T A;  2NZ8 B;  5KCV A;  1MIX A;  1DYN A;  1K5D B;  1WGU A;  2D11 A;  2HTH B;  4A6F B;  4HAV B;  4XWX A;  3HSA A;  1MKE A;  4NY0 A;  4QXA B;  5J3Q A;  4QJ5 B;  5DHF B;  2CY5 A;  5C6R A;  4K81 A;  3B77 A;  4HDO A;  3KSY A;  1FGY A;  3V5W A;  4QJ3 B;  1MK7 B;  1X11 A;  2XQN M;  4A6F A;  4WSF A;  4F7G A;  1V5U A;  1IRS A;  2KUP A;  2W2W A;  2CRF A;  4HAY B;  1H10 A;  2K2J A;  2GCL A;  3QWM A;  2GUM A;  2Z0O A;  3X23 A;  2YT0 A;  2K49 A;  2D4Q A;  2Z59 A;  4EMO A;  1OY2 A;  1OQN A;  3BIN A;  3IVF A;  2I1K A;  2X18 A;  4OT1 A;  3TVV A;  3PZD A;  2D9W A;  4TYZ A;  3F5R A;  1V5P A;  2BCJ A;  5LOP B;  3DXD A;  1DDW A;  2GS0 A;  2YS3 A;  3MDB C;  1TXD A;  4WVF B;  5D3W A;  2DTC A;  1EF1 A;  1WVH A;  2D9Z A;  2Z13 A;  2Z0P A;  2Y8F A;  5C79 A;  2H7E A;  2QKL A;  3FEH A;  1NTY A;  2DN6 A;  1M7R A;  2RGN B;  1EVH A;  3N7C A;  3KZ1 A;  3D8D A;  4KHO A;  4KVG B;  1X86 A;  2K8E A;  4DX9 0;  2YT1 A;  2V76 A;  1NI2 A;  2KUQ A;  5C16 A;  3DXC A;  2LUL A;  2KIG A;  2J59 M;  3A8P A;  2R09 A;  4IOY X;  3TCA A;  3MPX A;  1DDV A;  2MFQ A;  4MT7 A;  1PMS A;  2Z14 A;  1AQC A;  1ZM0 A;  3SV1 A;  4HAX B;  4HB2 B;  1TQZ A;  2Z0Q A;  2COF A;  4C0A A;  3FM8 C;  4GNK B;  4DXA B;  1XOD A;  3ULC A;  4DX8 A;  3ODX A;  1UNR A;  1WG7 A;  3DXE A;  3P6A A;  3PG7 A;  1PLS A;  3A98 B;  2DYN A;  2RVB B;  2IFS A;  2MWN B;  4BBK A;  2YRY A;  5HE2 A;  2Z4D A;  5EFX A;  1T77 A;  2R2Y A;  1ZSQ A;  5C5B B;  2VSZ A;  2RLO A;  1J0W A;  2K2U A;  1U2B A;  1V88 A;  2DFK A;  3ULB A;  1MAI A;  4DBB A;  1MIZ B;  1BWN A;  2UZR A;  5JP4 A;  2NBV A;  4IAP A;  2YS1 A;  5GOW B;  5C5B A;  3VIA A;  2YSZ A;  4K2O A;  5FI0 A;  4OSN A;  1GG3 A;  1UNQ A;  4CHJ A;  4MK0 A;  4ZRK A;  2P0H A;  3PVU A;  5DIF B;  1DBH A;  2Q13 A;  1OMW A;  2W2X D;  4HAW B;  4ZRJ A;  2GCJ A;  2COA A;  2N23 A;  3BJI A;  4CYE A;  1LW3 A;  2VKI A;  4IFS A;  2JP2 A;  1MI1 A;  1I2H A;  2D9X A;  3O96 A;  3VOQ A;  5D27 A;  2FJU B;  2J0M A;  1FGZ A;  1TJ6 A;  3UZT A;  2LKO A;  3HW2 B;  3HIE A;  1V5M A;  2D9V A;  5JLJ B;  2KGX B;  5M4Y B;  4H8S A;  5LON B;  5D3V A;  2EJ8 A;  3HQC A;  5D3Y A;  1XKE A;  3T06 A;  1U5F A;  2KIE A;  4HB4 B;  4QJ4 B;  4HB0 B;  2LOX A;  2GJY A;  2I1J A;  4A5K A;  4P7I A;  5LG4 B;  3NWA A;  2ZKM X;  3AU4 A;  2UZS A;  2EMT A;  1W1G A;  1ZC3 B;  3PVL A;  2P0D A;  3NW8 A;  3OHM B;  3P7Z A;  5I2S A;  1V61 A;  5CLQ B;  2YF0 A;  5FI1 A;  1LB1 A;  1GC7 A;  2P8V A;  1H4R A;  3ZVR A;  1U29 A;  2KCJ A;  1ZC4 B;  1MPH A;  3G9W A;  2DHI A;  3PP2 A;  1X1G A;  1KZG A;  2DKP A;  2AL6 A;  2J0K A;  3FSS A;  3AU5 A;  2RRF A;  4KHB B;  3NSU A;  1UNP A;  2J0J A;  2CY4 A;  3NWD A;  3KY9 A;  3TFM A;  3FVC A;  5I2M A;  2DKQ A; 
#chains in the Genus database with same CATH homology
 1WGQ A;  2DHK A;  3PEG A;  1XX0 A;  5L81 A;  1W1H A;  2L2I A;  1Q67 A;  2D9Y A;  2MDX A;  1X1F A;  4HAZ B;  4Y94 A;  1FAO A;  3CIK A;  3A8Q A;  4PNK A;  3QBV B;  5KQ1 A;  2QKM A;  4D0N B;  2ROV A;  1K5G B;  1V89 A;  1QQG A;  3ZDT A;  1SGH A;  3ML4 A;  2DX5 A;  2DX1 A;  1P5T A;  3OAN A;  2RNR B;  1B55 A;  1GC6 A;  1RJ2 A;  2ROZ B;  4KHA A;  2Y7B A;  1BTK A;  2D2Q A;  3PSC A;  4HB3 B;  1N3H A;  1NU2 A;  2EC1 A;  1XR0 B;  4EJN A;  1MK9 B;  3TO1 A;  2UVM A;  1ISN A;  1WJM A;  3CXB B;  1P6S A;  3PVW A;  2FJL A;  4GXB A;  1M7E A;  3GYO A;  5HE3 A;  2N0Y A;  3AJ4 A;  1UEF A;  3GYP A;  1FB8 A;  1XCG A;  4L6E A;  2DA0 A;  2NMB A;  4TKN A;  4EKU A;  2K00 A;  2P0F A;  1BTN A;  2ELA A;  2COC A;  2CAY A;  1P3R A;  1Y19 B;  1UPQ A;  1NTV A;  4WJ7 A;  3QIJ A;  4GN1 A;  5DH9 B;  4GMX B;  5CLL B;  2M38 A;  1SHC A;  5JHG A;  1U5E A;  4NSW A;  1I7A A;  4YON A;  4HHV A;  4YL8 A;  2E2X A;  2I5C A;  1WJ1 A;  2G35 A;  2ELB A;  3RCP A;  4GMV A;  2ZPY A;  5DHA B;  4K17 A;  3U7D A;  4HAU B;  1X05 A;  2RUK B;  1ZVR A;  1Z87 A;  1FOE A;  2M14 A;  3F0W A;  1KZ7 A;  1RRP B;  4GZU A;  4MY6 A;  3U8Z A;  4A6K A;  1PFJ A;  2VRW B;  4PQ0 A;  4F7H A;  2AEH A;  2PZ1 A;  1WI1 A;  2IYB A;  2DLW A;  3SNH A;  5DI9 B;  4HDQ A;  3TW1 A;  1UPR A;  1DRO A;  3D8F A;  4Z2N A;  1FHW A;  5D3X A;  3D8E A;  5HE1 A;  2OTX A;  2EMS A;  1BAK A;  2Y8G A;  4B6H A;  5JHH A;  2RSG A;  3KRW A;  2DYQ A;  2LG1 A;  2LYD A;  3WYF B;  4KAX B;  1QC6 A;  2L1C A;  1EGX A;  1U27 A;  3SUZ A;  4ZRI A;  3M1I B;  1KI1 B;  2COD A;  4GPT B;  2YS5 A;  2W2X C;  1DDM A;  3SO6 A;  1EAZ A;  1J19 A;  1FHO A;  5KQ4 A;  2LOZ A;  2I5F A;  4HAT B;  4Z2M B;  2OQB A;  1U5D A;  4A6H A;  1E5W A;  2MKR A;  3ODW A;  3HK0 A;  1Y5O A;  3WA0 A;  1U5G A;  2H7D A;  4CHM A;  2YVC A;  2HE7 A;  1XD4 A;  1FHX A;  4F7U P;  2D10 A;  2DHJ A;  3LJU X;  5J3Y A;  3KRX A;  3ODO A;  1AWE A;  3SYX A;  5HE0 A;  2R0D A;  1W1D A;  4K2P A;  2ADZ A;  5J3T A;  2NZ8 B;  5KCV A;  1MIX A;  1DYN A;  1K5D B;  1WGU A;  2D11 A;  2HTH B;  4A6F B;  4HAV B;  4XWX A;  1MKE A;  4NY0 A;  5J3Q A;  5DHF B;  2CY5 A;  5C6R A;  4K81 A;  4HDO A;  3KSY A;  1FGY A;  3V5W A;  1MK7 B;  1X11 A;  2XQN M;  4A6F A;  4WSF A;  4F7G A;  1V5U A;  1IRS A;  2KUP A;  2W2W A;  2CRF A;  4HAY B;  1H10 A;  2K2J A;  2GCL A;  3QWM A;  2Z0O A;  3X23 A;  2YT0 A;  2D4Q A;  4EMO A;  1OY2 A;  1OQN A;  3BIN A;  3IVF A;  2I1K A;  2X18 A;  3TVV A;  3PZD A;  2D9W A;  4TYZ A;  3F5R A;  1V5P A;  2BCJ A;  5LOP B;  3DXD A;  1DDW A;  2GS0 A;  2YS3 A;  3MDB C;  1TXD A;  4WVF B;  5D3W A;  2DTC A;  1EF1 A;  1WVH A;  2D9Z A;  2Z0P A;  2Y8F A;  5C79 A;  2H7E A;  2QKL A;  3FEH A;  1NTY A;  2DN6 A;  1M7R A;  2RGN B;  1EVH A;  3N7C A;  3KZ1 A;  3D8D A;  4KHO A;  4KVG B;  1X86 A;  4DX9 0;  2YT1 A;  2V76 A;  1NI2 A;  5C16 A;  3DXC A;  2LUL A;  2J59 M;  3A8P A;  2R09 A;  4IOY X;  3TCA A;  3MPX A;  1DDV A;  2MFQ A;  4MT7 A;  1PMS A;  1AQC A;  1ZM0 A;  3SV1 A;  4HAX B;  4HB2 B;  1TQZ A;  2Z0Q A;  2COF A;  4C0A A;  3FM8 C;  4DXA B;  1XOD A;  3ULC A;  4DX8 A;  3ODX A;  1UNR A;  1WG7 A;  3DXE A;  3P6A A;  3PG7 A;  1PLS A;  3A98 B;  2DYN A;  2RVB B;  2IFS A;  2MWN B;  4BBK A;  2YRY A;  5HE2 A;  5EFX A;  1ZSQ A;  5C5B B;  2VSZ A;  2RLO A;  1J0W A;  2K2U A;  1U2B A;  1V88 A;  2DFK A;  3ULB A;  1MAI A;  4DBB A;  1MIZ B;  1BWN A;  2UZR A;  5JP4 A;  4IAP A;  2YS1 A;  5GOW B;  5C5B A;  3VIA A;  2YSZ A;  4K2O A;  5FI0 A;  1GG3 A;  1UNQ A;  4CHJ A;  4MK0 A;  4ZRK A;  2P0H A;  3PVU A;  5DIF B;  1DBH A;  2Q13 A;  1OMW A;  2W2X D;  4HAW B;  4ZRJ A;  2GCJ A;  2COA A;  2N23 A;  3BJI A;  4CYE A;  1LW3 A;  2VKI A;  4IFS A;  2JP2 A;  1I2H A;  2D9X A;  3O96 A;  3VOQ A;  5D27 A;  2J0M A;  1FGZ A;  1TJ6 A;  3UZT A;  2LKO A;  3HW2 B;  1V5M A;  2D9V A;  5JLJ B;  2KGX B;  4H8S A;  5LON B;  5D3V A;  2EJ8 A;  3HQC A;  5D3Y A;  1XKE A;  3T06 A;  1U5F A;  4HB4 B;  4HB0 B;  2LOX A;  2GJY A;  2I1J A;  4A5K A;  4P7I A;  3AU4 A;  2UZS A;  2EMT A;  1W1G A;  1ZC3 B;  3PVL A;  2P0D A;  3P7Z A;  1V61 A;  5CLQ B;  2YF0 A;  5FI1 A;  1LB1 A;  1GC7 A;  2P8V A;  1H4R A;  3ZVR A;  1U29 A;  2KCJ A;  1ZC4 B;  1MPH A;  3G9W A;  2DHI A;  3PP2 A;  1X1G A;  1KZG A;  2DKP A;  2AL6 A;  2J0K A;  3FSS A;  3AU5 A;  4KHB B;  3NSU A;  1UNP A;  2J0J A;  2CY4 A;  3KY9 A;  3TFM A;  2DKQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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