1FHXA

Structure of the pleckstrin homology domain from grp1 in complex with inositol 1,3,4,5-tetrakisphosphate
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
123
structure length
123
Chain Sequence
NPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
pubmed doi rcsb
molecule tags Signaling protein
source organism Mus musculus
molecule keywords GUANINE NUCLEOTIDE EXCHANGE FACTOR AND INTEGRIN BINDING PROT
total genus 17
structure length 123
sequence length 123
chains with identical sequence B
ec nomenclature
pdb deposition date 2000-08-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1fhxA00
2DKQA 4A6HA 5DIFB 2DA0A 2QKLA 3SYXA 2DN6A 2L1CA 3FM8C 1UNRA 1AWEA 1GC6A 2LYDA 1BWNA 1AQCA 3DXEA 1W1DA 2N23A 1DDWA 3GYPA 1WJMA 2DX5A 1U29A 2M14A 4DXAB 4GZUA 4D0NB 1EVHA 2DFKA 2DX1A 3TCAA 3KRWA 5D27A 5DHFB 3DXCA 3WA0A 2J59M 1XKEA 2VRWB 1UPQA 3T06A 1V88A 1FGYA 1U5DA 2E2XA 2DTCA 4GMXB 4MK0A 5J3YA 4DX8A 2I5FA 4A6FA 2R09A 2CODA 3ULBA 3VOQA 4KHOA 1QC6A 5FI0A 3NSUA 2AL6A 1WJ1A 1UEFA 4K81A 1M7EA 2IFSA 1W1GA 2K2JA 1ZVRA 1P3RA 1Z87A 3ODXA 2DLWA 4KHBB 3AU5A 5C6RA 1PLSA 3A98B 5JHHA 3X23A 2YS1A 2I5CA 1W1HA 2COFA 1ISNA 1B55A 4XWXA 3G9WA 2D9YA 4IAPA 2Y8FA 2D11A 3PSCA 1SGHA 1GC7A 4DBBA 5CLLB 5JP4A 3HW2B 2EJ8A 2V76A 1X11A 1MKEA 1I7AA 3DXDA 4H8SA 4EMOA 1ZSQA 2UZRA 2ELBA 3P7ZA 4ZRJA 2MFQA 4DX90 2GCJA 2BCJA 2H7DA 1QQGA 2ZPYA 4C0AA 3ULCA 1U2BA 3ODOA 1V61A 3LJUX 5HE3A 3IVFA 2EMSA 3GYOA 1EAZA 2ROVA 1ZM0A 3PVUA 1WGQA 3PZDA 1P5TA 2YT0A 5HE1A 2D10A 2EC1A 2ROZB 4HB2B 4WSFA 2GS0A 2Y8GA 1U27A 4CHMA 1NU2A 1J0WA 2M38A 1BTKA 4K2OA 2HE7A 5CLQB 4GXBA 2JP2A 1KI1B 2KCJA 1K5DB 5C5BB 2AEHA 4L6EA 1DYNA 5JHGA 5C79A 1MPHA 1IRSA 5D3YA 3AJ4A 4KAXB 5L81A 2YRYA 3KRXA 4KVGB 5D3VA 1UNPA 3U7DA 3PVWA 2OTXA 3F0WA 3FSSA 2YVCA 3UZTA 4NSWA 1KZGA 4MT7A 2LULA 5DH9B 3V5WA 5J3QA 3A8PA 1OQNA 4P7IA 2XQNM 1MK9B 3ZVRA 4A5KA 2D9VA 1V89A 3KSYA 1XD4A 1EF1A 4HATB 2P8VA 4HAUB 4HHVA 5D3WA 3BJIA 3ZDTA 1FHOA 1BTNA 2FJLA 2DHKA 1LW3A 2RLOA 3MDBC 4HAYB 2DHJA 3SNHA 1XR0B 2P0FA 1X1GA 2W2XD 2Y7BA 3ODWA 2QKMA 4CHJA 1OY2A 3PVLA 3QIJA 5JLJB 3KZ1A 5KQ1A 4HDQA 1WI1A 1EGXA 1DBHA 2IYBA 2Z0QA 1KZ7A 3TFMA 5FI1A 5KCVA 3FEHA 1E5WA 2COCA 3O96A 2YSZA 3QWMA 2DYNA 3BINA 2VSZA 2RNRB 1XODA 4K17A 3HQCA 3N7CA 4HB3B 2RUKB 1MK7B 3MPXA 1J19A 1V5PA 2COAA 1Q67A 2DKPA 5J3TA 1XX0A 4YONA 2Z0OA 4K2PA 3D8FA 2I1KA 4MY6A 2RGNB 2OQBA 1DDMA 3QBVB 1FGZA 1Y19B 1FOEA 2MKRA 2YS5A 5C16A 1I2HA 4F7GA 2GJYA 2D9XA 4TYZA 5LONB 4A6FB 4NY0A 3D8DA 2HTHB 3PEGA 5GOWB 1X86A 1OMWA 2H7EA 2D9WA 4IFSA 1FHWA 3P6AA 4Z2MB 2NMBA 2KGXB 4ZRIA 4Z2NA 5EFXA 1RJ2A 2DYQA 1SHCA 2PZ1A 2Z0PA 2YT1A 1FAOA 5HE0A 2P0HA 1U5FA 2ADZA 1NTVA 3SO6A 1LB1A 3TVVA 3ML4A 3VIAA 3U8ZA 2KUPA 1UPRA 4HAVB 2RVBB 2P0DA 4GMVA 3RCPA 1H4RA 4PQ0A 2N0YA 2CY5A 1V5MA 1Y5OA 1X05A 1TQZA 5LOPB 1P6SA 1XCGA 3CXBB 3KY9A 2W2XC 2D2QA 2X18A 1MIXA 4A6KA 4IOYX 2EMTA 3D8EA 2Q13A 1N3HA 1U5GA 1TJ6A 3OANA 3SV1A 4GN1A 2R0DA 2CY4A 1PFJA 1DDVA 2L2IA 3SUZA 3PP2A 2J0MA 5HE2A 1TXDA 4Y94A 1NI2A 2G35A 1M7RA 2J0KA 4CYEA 2MWNB 2CRFA 2LG1A 1RRPB 2UVMA 5DHAB 4WVFB 1K5GB 1DROA 2ELAA 5C5BA 4PNKA 4F7HA 4HAXB 2K00A 1PMSA 1WG7A 2LKOA 2LOXA 2MDXA 2YS3A 2UZSA 4HDOA 1ZC4B 4ZRKA 4BBKA 1FHXA 2YF0A 1U5EA 3A8QA 1WGUA 3HK0A 2I1JA 4HAZB 3M1IB 2W2WA 5DI9B 2RSGA 1BAKA 3WYFB 4EJNA 4F7UP 3AU4A 4TKNA 1V5UA 1FB8A 2D4QA 2CAYA 2J0JA 4HAWB 4KHAA 1MIZB 4YL8A 3PG7A 4GPTB 1ZC3B 5KQ4A 4HB0B 1X1FA 5D3XA 1H10A 1MAIA 3TO1A 3TW1A 2NZ8B 2GCLA 2D9ZA 2DHIA 4EKUA 2K2UA 1WVHA 4HB4B 1UNQA 1GG3A 2VKIA 4B6HA 3F5RA 2LOZA 4WJ7A 3CIKA 1NTYA
chains in the Genus database with same CATH superfamily
2DKQA 4A6HA 5DIFB 2DA0A 2QKLA 3SYXA 2DN6A 2L1CA 3FM8C 1UNRA 1AWEA 1GC6A 2LYDA 2Z14A 1BWNA 1AQCA 2ZKMX 3DXEA 1W1DA 2N23A 1DDWA 3GYPA 1WJMA 2DX5A 1U29A 2M14A 4GOUA 4DXAB 4GZUA 4D0NB 1EVHA 2DFKA 2DX1A 3TCAA 3KRWA 5D27A 5DHFB 3DXCA 3WA0A 2J59M 1XKEA 2VRWB 1UPQA 3T06A 2KR0A 1V88A 1FGYA 1U5DA 2E2XA 2DTCA 4GMXB 4MK0A 5J3YA 4DX8A 2I5FA 4A6FA 2R09A 2CODA 3ULBA 4OT1A 3VOQA 4KHOA 1QC6A 5FI0A 3NSUA 2AL6A 1WJ1A 1UEFA 4K81A 1M7EA 2IFSA 1W1GA 2K2JA 1ZVRA 1P3RA 4QJ4B 1Z87A 3ODXA 2DLWA 4KHBB 3AU5A 3OHMB 2KUQA 5C6RA 1PLSA 3A98B 5JHHA 3X23A 2YS1A 2I5CA 1W1HA 2COFA 3NW8A 1ISNA 1B55A 2RRFA 4XWXA 3G9WA 2D9YA 4IAPA 2Y8FA 2D11A 3PSCA 1SGHA 1GC7A 4DBBA 5CLLB 5JP4A 3HW2B 2EJ8A 2V76A 1X11A 1MKEA 1I7AA 3DXDA 4H8SA 4EMOA 1ZSQA 2UZRA 2ELBA 3P7ZA 4ZRJA 2MFQA 1ZYIA 4DX90 2GCJA 2BCJA 2H7DA 1QQGA 2ZPYA 4C0AA 3ULCA 1U2BA 3ODOA 1V61A 3LJUX 5HE3A 3IVFA 2EMSA 3GYOA 1EAZA 2ROVA 2Z13A 1ZM0A 3PVUA 1WGQA 3PZDA 1P5TA 2YT0A 5HE1A 2D10A 2EC1A 2ROZB 4HB2B 4WSFA 2GS0A 2Y8GA 1U27A 4CHMA 1NU2A 2KIEA 1J0WA 2M38A 1BTKA 4K2OA 2HE7A 5CLQB 4GXBA 2JP2A 1KI1B 2KCJA 1K5DB 5C5BB 2AEHA 3HSAA 4L6EA 1DYNA 5JHGA 5C79A 1MPHA 1IRSA 5D3YA 3AJ4A 4KAXB 5L81A 2YRYA 3KRXA 4KVGB 5D3VA 1UNPA 3U7DA 3PVWA 2OTXA 3F0WA 3NWAA 3FSSA 2YVCA 3UZTA 4NSWA 1KZGA 4MT7A 2LULA 5DH9B 3V5WA 5J3QA 3A8PA 1OQNA 2K8EA 4P7IA 4QXAB 2XQNM 1MK9B 3ZVRA 4A5KA 2D9VA 1V89A 3KSYA 1XD4A 1EF1A 4HATB 2P8VA 2FJUB 4HAUB 3FVCA 4HHVA 3BJIA 5D3WA 3ZDTA 1FHOA 1BTNA 2FJLA 4DIXA 2DHKA 1LW3A 2RLOA 3MDBC 4HAYB 2DHJA 3SNHA 3B77A 1XR0B 2P0FA 1X1GA 2W2XD 2Y7BA 3ODWA 2QKMA 4CHJA 1OY2A 3PVLA 3QIJA 5JLJB 3KZ1A 5KQ1A 4HDQA 1WI1A 1EGXA 2NBVA 1DBHA 2IYBA 2Z0QA 1KZ7A 3TFMA 5FI1A 5KCVA 3FEHA 1E5WA 2COCA 3O96A 2YSZA 3QWMA 5I2MA 2DYNA 3BINA 2VSZA 2RNRB 1XODA 4K17A 3HQCA 5IRSA 3N7CA 4HB3B 2RUKB 1MK7B 3MPXA 1J19A 1V5PA 2COAA 1Q67A 2DKPA 5J3TA 1XX0A 4YONA 2Z0OA 4K2PA 3D8FA 2I1KA 2K49A 3NWDA 4MY6A 2RGNB 2OQBA 5LG4B 1DDMA 4OSNA 3QBVB 1FGZA 1Y19B 1FOEA 2MKRA 2YS5A 5C16A 1I2HA 4F7GA 2GJYA 3U12A 2D9XA 4TYZA 5LONB 4A6FB 4NY0A 3D8DA 2HTHB 3PEGA 5GOWB 1MI1A 1X86A 1OMWA 2H7EA 2D9WA 4IFSA 1FHWA 3P6AA 4Z2MB 2NMBA 2KGXB 4ZRIA 4Z2NA 4L1RA 5EFXA 1RJ2A 2DYQA 1SHCA 2PZ1A 2Z0PA 2YT1A 1FAOA 2YT2A 5HE0A 2P0HA 1U5FA 4KHBA 2ADZA 1NTVA 3SO6A 1LB1A 3TVVA 3ML4A 3VIAA 2KIGA 3U8ZA 2KUPA 1UPRA 4HAVB 2RVBB 2P0DA 4GMVA 3RCPA 1H4RA 4PQ0A 1T77A 2N0YA 2CY5A 1V5MA 1Y5OA 1X05A 4D6WA 1TQZA 5LOPB 4CSQA 1P6SA 1XCGA 3CXBB 3KY9A 2W2XC 2D2QA 2X18A 1MIXA 4A6KA 4IOYX 2EMTA 3D8EA 2Q13A 1N3HA 1U5GA 1TJ6A 3OANA 3SV1A 4GN1A 2R0DA 2CY4A 2Z4DA 1PFJA 1DDVA 2L2IA 3SUZA 3PP2A 2J0MA 4HSIA 3DCXA 5HE2A 1TXDA 4Y94A 1NI2A 2G35A 1M7RA 2J0KA 4CYEA 2MWNB 2CRFA 2LG1A 1RRPB 2UVMA 5DHAB 2GUMA 4WVFB 1K5GB 1DROA 2ELAA 5C5BA 4PNKA 4F7HA 5I2SA 4HAXB 2K00A 1PMSA 1WG7A 2LKOA 2LOXA 2MDXA 2YS3A 2UZSA 4HDOA 1ZC4B 4ZRKA 4BBKA 1FHXA 2YF0A 1U5EA 3A8QA 1WGUA 3HK0A 2I1JA 4HAZB 3M1IB 2W2WA 5DI9B 2RSGA 1BAKA 3WYFB 4EJNA 4F7UP 3AU4A 4TKNA 3HIEA 1V5UA 1FB8A 2D4QA 4QJ5B 3A58A 2CAYA 2J0JA 4HAWB 4KHAA 1MIZB 4YL8A 3NWFA 3PG7A 4GPTB 1ZC3B 5KQ4A 4HB0B 1X1FA 5D3XA 1H10A 1MAIA 3TO1A 4QJ3B 2NZ8B 2R2YA 2GCLA 3TW1A 2D9ZA 2DHIA 4EKUA 2K2UA 1WVHA 2Z59A 4HB4B 5M4YB 1UNQA 1GG3A 2VKIA 4B6HA 3F5RA 2LOZA 4WJ7A 4GNKB 3CIKA 1NTYA
chains in the Genus database with same CATH topology
2DKQA 4A6HA 5DIFB 2DA0A 2QKLA 3SYXA 2DN6A 2L1CA 3FM8C 1UNRA 1AWEA 1GC6A 2LYDA 1BWNA 1AQCA 3DXEA 1W1DA 2N23A 1DDWA 3GYPA 1WJMA 2DX5A 1U29A 2M14A 4DXAB 4GZUA 4D0NB 1EVHA 2DFKA 2DX1A 3TCAA 3KRWA 5D27A 5DHFB 3DXCA 3WA0A 2J59M 1XKEA 2VRWB 1UPQA 3T06A 1V88A 1FGYA 1U5DA 2E2XA 2DTCA 4GMXB 4MK0A 5J3YA 4DX8A 2I5FA 4A6FA 2R09A 2CODA 3ULBA 3VOQA 4KHOA 1QC6A 5FI0A 3NSUA 2AL6A 1WJ1A 1UEFA 4K81A 1M7EA 2IFSA 1W1GA 2K2JA 1ZVRA 1P3RA 1Z87A 3ODXA 2DLWA 4KHBB 3AU5A 5C6RA 1PLSA 3A98B 5JHHA 3X23A 2YS1A 2I5CA 1W1HA 2COFA 1ISNA 1B55A 4XWXA 3G9WA 2D9YA 4IAPA 2Y8FA 2D11A 3PSCA 1SGHA 1GC7A 4DBBA 5CLLB 5JP4A 3HW2B 2EJ8A 2V76A 1X11A 1MKEA 1I7AA 3DXDA 4H8SA 4EMOA 1ZSQA 2UZRA 2ELBA 3P7ZA 4ZRJA 2MFQA 4DX90 2GCJA 2BCJA 2H7DA 1QQGA 2ZPYA 4C0AA 3ULCA 1U2BA 3ODOA 1V61A 3LJUX 5HE3A 3IVFA 2EMSA 3GYOA 1EAZA 2ROVA 1ZM0A 3PVUA 1WGQA 3PZDA 1P5TA 2YT0A 5HE1A 2D10A 2EC1A 2ROZB 4HB2B 4WSFA 2GS0A 2Y8GA 1U27A 4CHMA 1NU2A 1J0WA 2M38A 1BTKA 4K2OA 2HE7A 5CLQB 4GXBA 2JP2A 1KI1B 2KCJA 1K5DB 5C5BB 2AEHA 4L6EA 1DYNA 5JHGA 5C79A 1MPHA 1IRSA 5D3YA 3AJ4A 4KAXB 5L81A 2YRYA 3KRXA 4KVGB 5D3VA 1UNPA 3U7DA 3PVWA 2OTXA 3F0WA 3FSSA 2YVCA 3UZTA 4NSWA 1KZGA 4MT7A 2LULA 5DH9B 3V5WA 5J3QA 3A8PA 1OQNA 4P7IA 2XQNM 1MK9B 3ZVRA 4A5KA 2D9VA 1V89A 3KSYA 1XD4A 1EF1A 4HATB 2P8VA 4HAUB 4HHVA 5D3WA 3BJIA 3ZDTA 1FHOA 1BTNA 2FJLA 2DHKA 1LW3A 2RLOA 3MDBC 4HAYB 2DHJA 3SNHA 1XR0B 2P0FA 1X1GA 2W2XD 2Y7BA 3ODWA 2QKMA 4CHJA 1OY2A 3PVLA 3QIJA 5JLJB 3KZ1A 5KQ1A 4HDQA 1WI1A 1EGXA 1DBHA 2IYBA 2Z0QA 1KZ7A 3TFMA 5FI1A 5KCVA 3FEHA 1E5WA 2COCA 3O96A 2YSZA 3QWMA 2DYNA 3BINA 2VSZA 2RNRB 1XODA 4K17A 3HQCA 3N7CA 4HB3B 2RUKB 1MK7B 3MPXA 1J19A 1V5PA 2COAA 1Q67A 2DKPA 5J3TA 1XX0A 4YONA 2Z0OA 4K2PA 3D8FA 2I1KA 4MY6A 2RGNB 2OQBA 1DDMA 3QBVB 1FGZA 1Y19B 1FOEA 2MKRA 2YS5A 5C16A 1I2HA 4F7GA 2GJYA 2D9XA 4TYZA 5LONB 4A6FB 4NY0A 3D8DA 2HTHB 3PEGA 5GOWB 1X86A 1OMWA 2H7EA 2D9WA 4IFSA 1FHWA 3P6AA 4Z2MB 2NMBA 2KGXB 4ZRIA 4Z2NA 5EFXA 1RJ2A 2DYQA 1SHCA 2PZ1A 2Z0PA 2YT1A 1FAOA 5HE0A 2P0HA 1U5FA 2ADZA 1NTVA 3SO6A 1LB1A 3TVVA 3ML4A 3VIAA 3U8ZA 2KUPA 1UPRA 4HAVB 2RVBB 2P0DA 4GMVA 3RCPA 1H4RA 4PQ0A 2N0YA 2CY5A 1V5MA 1Y5OA 1X05A 1TQZA 5LOPB 1P6SA 1XCGA 3CXBB 3KY9A 2W2XC 2D2QA 2X18A 1MIXA 4A6KA 4IOYX 2EMTA 3D8EA 2Q13A 1N3HA 1U5GA 1TJ6A 3OANA 3SV1A 4GN1A 2R0DA 2CY4A 1PFJA 1DDVA 2L2IA 3SUZA 3PP2A 2J0MA 5HE2A 1TXDA 4Y94A 1NI2A 2G35A 1M7RA 2J0KA 4CYEA 2MWNB 2CRFA 2LG1A 1RRPB 2UVMA 5DHAB 4WVFB 1K5GB 1DROA 2ELAA 5C5BA 4PNKA 4F7HA 4HAXB 2K00A 1PMSA 1WG7A 2LKOA 2LOXA 2MDXA 2YS3A 2UZSA 4HDOA 1ZC4B 4ZRKA 4BBKA 1FHXA 2YF0A 1U5EA 3A8QA 1WGUA 3HK0A 2I1JA 4HAZB 3M1IB 2W2WA 5DI9B 2RSGA 1BAKA 3WYFB 4EJNA 4F7UP 3AU4A 4TKNA 1V5UA 1FB8A 2D4QA 2CAYA 2J0JA 4HAWB 4KHAA 1MIZB 4YL8A 3PG7A 4GPTB 1ZC3B 5KQ4A 4HB0B 1X1FA 5D3XA 1H10A 1MAIA 3TO1A 3TW1A 2NZ8B 2GCLA 2D9ZA 2DHIA 4EKUA 2K2UA 1WVHA 4HB4B 1UNQA 1GG3A 2VKIA 4B6HA 3F5RA 2LOZA 4WJ7A 3CIKA 1NTYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DKQ A;  4A6H A;  5DIF B;  2DA0 A;  2QKL A;  3SYX A;  2DN6 A;  2L1C A;  3FM8 C;  1UNR A;  1AWE A;  1GC6 A;  2LYD A;  1BWN A;  1AQC A;  3DXE A;  1W1D A;  2N23 A;  1DDW A;  3GYP A;  1WJM A;  2DX5 A;  1U29 A;  2M14 A;  4DXA B;  4GZU A;  4D0N B;  1EVH A;  2DFK A;  2DX1 A;  3TCA A;  3KRW A;  5D27 A;  5DHF B;  3DXC A;  3WA0 A;  2J59 M;  1XKE A;  2VRW B;  1UPQ A;  3T06 A;  1V88 A;  1FGY A;  1U5D A;  2E2X A;  2DTC A;  4GMX B;  4MK0 A;  5J3Y A;  4DX8 A;  2I5F A;  4A6F A;  2R09 A;  2COD A;  3ULB A;  3VOQ A;  4KHO A;  1QC6 A;  5FI0 A;  3NSU A;  2AL6 A;  1WJ1 A;  1UEF A;  4K81 A;  1M7E A;  2IFS A;  1W1G A;  2K2J A;  1ZVR A;  1P3R A;  1Z87 A;  3ODX A;  2DLW A;  4KHB B;  3AU5 A;  5C6R A;  1PLS A;  3A98 B;  5JHH A;  3X23 A;  2YS1 A;  2I5C A;  1W1H A;  2COF A;  1ISN A;  1B55 A;  4XWX A;  3G9W A;  2D9Y A;  4IAP A;  2Y8F A;  2D11 A;  3PSC A;  1SGH A;  1GC7 A;  4DBB A;  5CLL B;  5JP4 A;  3HW2 B;  2EJ8 A;  2V76 A;  1X11 A;  1MKE A;  1I7A A;  3DXD A;  4H8S A;  4EMO A;  1ZSQ A;  2UZR A;  2ELB A;  3P7Z A;  4ZRJ A;  2MFQ A;  4DX9 0;  2GCJ A;  2BCJ A;  2H7D A;  1QQG A;  2ZPY A;  4C0A A;  3ULC A;  1U2B A;  3ODO A;  1V61 A;  3LJU X;  5HE3 A;  3IVF A;  2EMS A;  3GYO A;  1EAZ A;  2ROV A;  1ZM0 A;  3PVU A;  1WGQ A;  3PZD A;  1P5T A;  2YT0 A;  5HE1 A;  2D10 A;  2EC1 A;  2ROZ B;  4HB2 B;  4WSF A;  2GS0 A;  2Y8G A;  1U27 A;  4CHM A;  1NU2 A;  1J0W A;  2M38 A;  1BTK A;  4K2O A;  2HE7 A;  5CLQ B;  4GXB A;  2JP2 A;  1KI1 B;  2KCJ A;  1K5D B;  5C5B B;  2AEH A;  4L6E A;  1DYN A;  5JHG A;  5C79 A;  1MPH A;  1IRS A;  5D3Y A;  3AJ4 A;  4KAX B;  5L81 A;  2YRY A;  3KRX A;  4KVG B;  5D3V A;  1UNP A;  3U7D A;  3PVW A;  2OTX A;  3F0W A;  3FSS A;  2YVC A;  3UZT A;  4NSW A;  1KZG A;  4MT7 A;  2LUL A;  5DH9 B;  3V5W A;  5J3Q A;  3A8P A;  1OQN A;  4P7I A;  2XQN M;  1MK9 B;  3ZVR A;  4A5K A;  2D9V A;  1V89 A;  3KSY A;  1XD4 A;  1EF1 A;  4HAT B;  2P8V A;  4HAU B;  4HHV A;  5D3W A;  3BJI A;  3ZDT A;  1FHO A;  1BTN A;  2FJL A;  2DHK A;  1LW3 A;  2RLO A;  3MDB C;  4HAY B;  2DHJ A;  3SNH A;  1XR0 B;  2P0F A;  1X1G A;  2W2X D;  2Y7B A;  3ODW A;  2QKM A;  4CHJ A;  1OY2 A;  3PVL A;  3QIJ A;  5JLJ B;  3KZ1 A;  5KQ1 A;  4HDQ A;  1WI1 A;  1EGX A;  1DBH A;  2IYB A;  2Z0Q A;  1KZ7 A;  3TFM A;  5FI1 A;  5KCV A;  3FEH A;  1E5W A;  2COC A;  3O96 A;  2YSZ A;  3QWM A;  2DYN A;  3BIN A;  2VSZ A;  2RNR B;  1XOD A;  4K17 A;  3HQC A;  3N7C A;  4HB3 B;  2RUK B;  1MK7 B;  3MPX A;  1J19 A;  1V5P A;  2COA A;  1Q67 A;  2DKP A;  5J3T A;  1XX0 A;  4YON A;  2Z0O A;  4K2P A;  3D8F A;  2I1K A;  4MY6 A;  2RGN B;  2OQB A;  1DDM A;  3QBV B;  1FGZ A;  1Y19 B;  1FOE A;  2MKR A;  2YS5 A;  5C16 A;  1I2H A;  4F7G A;  2GJY A;  2D9X A;  4TYZ A;  5LON B;  4A6F B;  4NY0 A;  3D8D A;  2HTH B;  3PEG A;  5GOW B;  1X86 A;  1OMW A;  2H7E A;  2D9W A;  4IFS A;  1FHW A;  3P6A A;  4Z2M B;  2NMB A;  2KGX B;  4ZRI A;  4Z2N A;  5EFX A;  1RJ2 A;  2DYQ A;  1SHC A;  2PZ1 A;  2Z0P A;  2YT1 A;  1FAO A;  5HE0 A;  2P0H A;  1U5F A;  2ADZ A;  1NTV A;  3SO6 A;  1LB1 A;  3TVV A;  3ML4 A;  3VIA A;  3U8Z A;  2KUP A;  1UPR A;  4HAV B;  2RVB B;  2P0D A;  4GMV A;  3RCP A;  1H4R A;  4PQ0 A;  2N0Y A;  2CY5 A;  1V5M A;  1Y5O A;  1X05 A;  1TQZ A;  5LOP B;  1P6S A;  1XCG A;  3CXB B;  3KY9 A;  2W2X C;  2D2Q A;  2X18 A;  1MIX A;  4A6K A;  4IOY X;  2EMT A;  3D8E A;  2Q13 A;  1N3H A;  1U5G A;  1TJ6 A;  3OAN A;  3SV1 A;  4GN1 A;  2R0D A;  2CY4 A;  1PFJ A;  1DDV A;  2L2I A;  3SUZ A;  3PP2 A;  2J0M A;  5HE2 A;  1TXD A;  4Y94 A;  1NI2 A;  2G35 A;  1M7R A;  2J0K A;  4CYE A;  2MWN B;  2CRF A;  2LG1 A;  1RRP B;  2UVM A;  5DHA B;  4WVF B;  1K5G B;  1DRO A;  2ELA A;  5C5B A;  4PNK A;  4F7H A;  4HAX B;  2K00 A;  1PMS A;  1WG7 A;  2LKO A;  2LOX A;  2MDX A;  2YS3 A;  2UZS A;  4HDO A;  1ZC4 B;  4ZRK A;  4BBK A;  1FHX A;  2YF0 A;  1U5E A;  3A8Q A;  1WGU A;  3HK0 A;  2I1J A;  4HAZ B;  3M1I B;  2W2W A;  5DI9 B;  2RSG A;  1BAK A;  3WYF B;  4EJN A;  4F7U P;  3AU4 A;  4TKN A;  1V5U A;  1FB8 A;  2D4Q A;  2CAY A;  2J0J A;  4HAW B;  4KHA A;  1MIZ B;  4YL8 A;  3PG7 A;  4GPT B;  1ZC3 B;  5KQ4 A;  4HB0 B;  1X1F A;  5D3X A;  1H10 A;  1MAI A;  3TO1 A;  3TW1 A;  2NZ8 B;  2GCL A;  2D9Z A;  2DHI A;  4EKU A;  2K2U A;  1WVH A;  4HB4 B;  1UNQ A;  1GG3 A;  2VKI A;  4B6H A;  3F5R A;  2LOZ A;  4WJ7 A;  3CIK A;  1NTY A; 
#chains in the Genus database with same CATH topology
 2DKQ A;  4A6H A;  5DIF B;  2DA0 A;  2QKL A;  3SYX A;  2DN6 A;  2L1C A;  3FM8 C;  1UNR A;  1AWE A;  1GC6 A;  2LYD A;  2Z14 A;  1BWN A;  1AQC A;  2ZKM X;  3DXE A;  1W1D A;  2N23 A;  1DDW A;  3GYP A;  1WJM A;  2DX5 A;  1U29 A;  2M14 A;  4GOU A;  4DXA B;  4GZU A;  4D0N B;  1EVH A;  2DFK A;  2DX1 A;  3TCA A;  3KRW A;  5D27 A;  5DHF B;  3DXC A;  3WA0 A;  2J59 M;  1XKE A;  2VRW B;  1UPQ A;  3T06 A;  2KR0 A;  1V88 A;  1FGY A;  1U5D A;  2E2X A;  2DTC A;  4GMX B;  4MK0 A;  5J3Y A;  4DX8 A;  2I5F A;  4A6F A;  2R09 A;  2COD A;  3ULB A;  4OT1 A;  3VOQ A;  4KHO A;  1QC6 A;  5FI0 A;  3NSU A;  2AL6 A;  1WJ1 A;  1UEF A;  4K81 A;  1M7E A;  2IFS A;  1W1G A;  2K2J A;  1ZVR A;  1P3R A;  4QJ4 B;  1Z87 A;  3ODX A;  2DLW A;  4KHB B;  3AU5 A;  3OHM B;  2KUQ A;  5C6R A;  1PLS A;  3A98 B;  5JHH A;  3X23 A;  2YS1 A;  2I5C A;  1W1H A;  2COF A;  3NW8 A;  1ISN A;  1B55 A;  2RRF A;  4XWX A;  3G9W A;  2D9Y A;  4IAP A;  2Y8F A;  2D11 A;  3PSC A;  1SGH A;  1GC7 A;  4DBB A;  5CLL B;  5JP4 A;  3HW2 B;  2EJ8 A;  2V76 A;  1X11 A;  1MKE A;  1I7A A;  3DXD A;  4H8S A;  4EMO A;  1ZSQ A;  2UZR A;  2ELB A;  3P7Z A;  4ZRJ A;  2MFQ A;  1ZYI A;  4DX9 0;  2GCJ A;  2BCJ A;  2H7D A;  1QQG A;  2ZPY A;  4C0A A;  3ULC A;  1U2B A;  3ODO A;  1V61 A;  3LJU X;  5HE3 A;  3IVF A;  2EMS A;  3GYO A;  1EAZ A;  2ROV A;  2Z13 A;  1ZM0 A;  3PVU A;  1WGQ A;  3PZD A;  1P5T A;  2YT0 A;  5HE1 A;  2D10 A;  2EC1 A;  2ROZ B;  4HB2 B;  4WSF A;  2GS0 A;  2Y8G A;  1U27 A;  4CHM A;  1NU2 A;  2KIE A;  1J0W A;  2M38 A;  1BTK A;  4K2O A;  2HE7 A;  5CLQ B;  4GXB A;  2JP2 A;  1KI1 B;  2KCJ A;  1K5D B;  5C5B B;  2AEH A;  3HSA A;  4L6E A;  1DYN A;  5JHG A;  5C79 A;  1MPH A;  1IRS A;  5D3Y A;  3AJ4 A;  4KAX B;  5L81 A;  2YRY A;  3KRX A;  4KVG B;  5D3V A;  1UNP A;  3U7D A;  3PVW A;  2OTX A;  3F0W A;  3NWA A;  3FSS A;  2YVC A;  3UZT A;  4NSW A;  1KZG A;  4MT7 A;  2LUL A;  5DH9 B;  3V5W A;  5J3Q A;  3A8P A;  1OQN A;  2K8E A;  4P7I A;  4QXA B;  2XQN M;  1MK9 B;  3ZVR A;  4A5K A;  2D9V A;  1V89 A;  3KSY A;  1XD4 A;  1EF1 A;  4HAT B;  2P8V A;  2FJU B;  4HAU B;  3FVC A;  4HHV A;  3BJI A;  5D3W A;  3ZDT A;  1FHO A;  1BTN A;  2FJL A;  4DIX A;  2DHK A;  1LW3 A;  2RLO A;  3MDB C;  4HAY B;  2DHJ A;  3SNH A;  3B77 A;  1XR0 B;  2P0F A;  1X1G A;  2W2X D;  2Y7B A;  3ODW A;  2QKM A;  4CHJ A;  1OY2 A;  3PVL A;  3QIJ A;  5JLJ B;  3KZ1 A;  5KQ1 A;  4HDQ A;  1WI1 A;  1EGX A;  2NBV A;  1DBH A;  2IYB A;  2Z0Q A;  1KZ7 A;  3TFM A;  5FI1 A;  5KCV A;  3FEH A;  1E5W A;  2COC A;  3O96 A;  2YSZ A;  3QWM A;  5I2M A;  2DYN A;  3BIN A;  2VSZ A;  2RNR B;  1XOD A;  4K17 A;  3HQC A;  5IRS A;  3N7C A;  4HB3 B;  2RUK B;  1MK7 B;  3MPX A;  1J19 A;  1V5P A;  2COA A;  1Q67 A;  2DKP A;  5J3T A;  1XX0 A;  4YON A;  2Z0O A;  4K2P A;  3D8F A;  2I1K A;  2K49 A;  3NWD A;  4MY6 A;  2RGN B;  2OQB A;  5LG4 B;  1DDM A;  4OSN A;  3QBV B;  1FGZ A;  1Y19 B;  1FOE A;  2MKR A;  2YS5 A;  5C16 A;  1I2H A;  4F7G A;  2GJY A;  3U12 A;  2D9X A;  4TYZ A;  5LON B;  4A6F B;  4NY0 A;  3D8D A;  2HTH B;  3PEG A;  5GOW B;  1MI1 A;  1X86 A;  1OMW A;  2H7E A;  2D9W A;  4IFS A;  1FHW A;  3P6A A;  4Z2M B;  2NMB A;  2KGX B;  4ZRI A;  4Z2N A;  4L1R A;  5EFX A;  1RJ2 A;  2DYQ A;  1SHC A;  2PZ1 A;  2Z0P A;  2YT1 A;  1FAO A;  2YT2 A;  5HE0 A;  2P0H A;  1U5F A;  4KHB A;  2ADZ A;  1NTV A;  3SO6 A;  1LB1 A;  3TVV A;  3ML4 A;  3VIA A;  2KIG A;  3U8Z A;  2KUP A;  1UPR A;  4HAV B;  2RVB B;  2P0D A;  4GMV A;  3RCP A;  1H4R A;  4PQ0 A;  1T77 A;  2N0Y A;  2CY5 A;  1V5M A;  1Y5O A;  1X05 A;  4D6W A;  1TQZ A;  5LOP B;  4CSQ A;  1P6S A;  1XCG A;  3CXB B;  3KY9 A;  2W2X C;  2D2Q A;  2X18 A;  1MIX A;  4A6K A;  4IOY X;  2EMT A;  3D8E A;  2Q13 A;  1N3H A;  1U5G A;  1TJ6 A;  3OAN A;  3SV1 A;  4GN1 A;  2R0D A;  2CY4 A;  2Z4D A;  1PFJ A;  1DDV A;  2L2I A;  3SUZ A;  3PP2 A;  2J0M A;  4HSI A;  3DCX A;  5HE2 A;  1TXD A;  4Y94 A;  1NI2 A;  2G35 A;  1M7R A;  2J0K A;  4CYE A;  2MWN B;  2CRF A;  2LG1 A;  1RRP B;  2UVM A;  5DHA B;  2GUM A;  4WVF B;  1K5G B;  1DRO A;  2ELA A;  5C5B A;  4PNK A;  4F7H A;  5I2S A;  4HAX B;  2K00 A;  1PMS A;  1WG7 A;  2LKO A;  2LOX A;  2MDX A;  2YS3 A;  2UZS A;  4HDO A;  1ZC4 B;  4ZRK A;  4BBK A;  1FHX A;  2YF0 A;  1U5E A;  3A8Q A;  1WGU A;  3HK0 A;  2I1J A;  4HAZ B;  3M1I B;  2W2W A;  5DI9 B;  2RSG A;  1BAK A;  3WYF B;  4EJN A;  4F7U P;  3AU4 A;  4TKN A;  3HIE A;  1V5U A;  1FB8 A;  2D4Q A;  4QJ5 B;  3A58 A;  2CAY A;  2J0J A;  4HAW B;  4KHA A;  1MIZ B;  4YL8 A;  3NWF A;  3PG7 A;  4GPT B;  1ZC3 B;  5KQ4 A;  4HB0 B;  1X1F A;  5D3X A;  1H10 A;  1MAI A;  3TO1 A;  4QJ3 B;  2NZ8 B;  2R2Y A;  2GCL A;  3TW1 A;  2D9Z A;  2DHI A;  4EKU A;  2K2U A;  1WVH A;  2Z59 A;  4HB4 B;  5M4Y B;  1UNQ A;  1GG3 A;  2VKI A;  4B6H A;  3F5R A;  2LOZ A;  4WJ7 A;  4GNK B;  3CIK A;  1NTY A; 
#chains in the Genus database with same CATH homology
 2DKQ A;  4A6H A;  5DIF B;  2DA0 A;  2QKL A;  3SYX A;  2DN6 A;  2L1C A;  3FM8 C;  1UNR A;  1AWE A;  1GC6 A;  2LYD A;  1BWN A;  1AQC A;  3DXE A;  1W1D A;  2N23 A;  1DDW A;  3GYP A;  1WJM A;  2DX5 A;  1U29 A;  2M14 A;  4DXA B;  4GZU A;  4D0N B;  1EVH A;  2DFK A;  2DX1 A;  3TCA A;  3KRW A;  5D27 A;  5DHF B;  3DXC A;  3WA0 A;  2J59 M;  1XKE A;  2VRW B;  1UPQ A;  3T06 A;  1V88 A;  1FGY A;  1U5D A;  2E2X A;  2DTC A;  4GMX B;  4MK0 A;  5J3Y A;  4DX8 A;  2I5F A;  4A6F A;  2R09 A;  2COD A;  3ULB A;  3VOQ A;  4KHO A;  1QC6 A;  5FI0 A;  3NSU A;  2AL6 A;  1WJ1 A;  1UEF A;  4K81 A;  1M7E A;  2IFS A;  1W1G A;  2K2J A;  1ZVR A;  1P3R A;  1Z87 A;  3ODX A;  2DLW A;  4KHB B;  3AU5 A;  5C6R A;  1PLS A;  3A98 B;  5JHH A;  3X23 A;  2YS1 A;  2I5C A;  1W1H A;  2COF A;  1ISN A;  1B55 A;  4XWX A;  3G9W A;  2D9Y A;  4IAP A;  2Y8F A;  2D11 A;  3PSC A;  1SGH A;  1GC7 A;  4DBB A;  5CLL B;  5JP4 A;  3HW2 B;  2EJ8 A;  2V76 A;  1X11 A;  1MKE A;  1I7A A;  3DXD A;  4H8S A;  4EMO A;  1ZSQ A;  2UZR A;  2ELB A;  3P7Z A;  4ZRJ A;  2MFQ A;  4DX9 0;  2GCJ A;  2BCJ A;  2H7D A;  1QQG A;  2ZPY A;  4C0A A;  3ULC A;  1U2B A;  3ODO A;  1V61 A;  3LJU X;  5HE3 A;  3IVF A;  2EMS A;  3GYO A;  1EAZ A;  2ROV A;  1ZM0 A;  3PVU A;  1WGQ A;  3PZD A;  1P5T A;  2YT0 A;  5HE1 A;  2D10 A;  2EC1 A;  2ROZ B;  4HB2 B;  4WSF A;  2GS0 A;  2Y8G A;  1U27 A;  4CHM A;  1NU2 A;  1J0W A;  2M38 A;  1BTK A;  4K2O A;  2HE7 A;  5CLQ B;  4GXB A;  2JP2 A;  1KI1 B;  2KCJ A;  1K5D B;  5C5B B;  2AEH A;  4L6E A;  1DYN A;  5JHG A;  5C79 A;  1MPH A;  1IRS A;  5D3Y A;  3AJ4 A;  4KAX B;  5L81 A;  2YRY A;  3KRX A;  4KVG B;  5D3V A;  1UNP A;  3U7D A;  3PVW A;  2OTX A;  3F0W A;  3FSS A;  2YVC A;  3UZT A;  4NSW A;  1KZG A;  4MT7 A;  2LUL A;  5DH9 B;  3V5W A;  5J3Q A;  3A8P A;  1OQN A;  4P7I A;  2XQN M;  1MK9 B;  3ZVR A;  4A5K A;  2D9V A;  1V89 A;  3KSY A;  1XD4 A;  1EF1 A;  4HAT B;  2P8V A;  4HAU B;  4HHV A;  5D3W A;  3BJI A;  3ZDT A;  1FHO A;  1BTN A;  2FJL A;  2DHK A;  1LW3 A;  2RLO A;  3MDB C;  4HAY B;  2DHJ A;  3SNH A;  1XR0 B;  2P0F A;  1X1G A;  2W2X D;  2Y7B A;  3ODW A;  2QKM A;  4CHJ A;  1OY2 A;  3PVL A;  3QIJ A;  5JLJ B;  3KZ1 A;  5KQ1 A;  4HDQ A;  1WI1 A;  1EGX A;  1DBH A;  2IYB A;  2Z0Q A;  1KZ7 A;  3TFM A;  5FI1 A;  5KCV A;  3FEH A;  1E5W A;  2COC A;  3O96 A;  2YSZ A;  3QWM A;  2DYN A;  3BIN A;  2VSZ A;  2RNR B;  1XOD A;  4K17 A;  3HQC A;  3N7C A;  4HB3 B;  2RUK B;  1MK7 B;  3MPX A;  1J19 A;  1V5P A;  2COA A;  1Q67 A;  2DKP A;  5J3T A;  1XX0 A;  4YON A;  2Z0O A;  4K2P A;  3D8F A;  2I1K A;  4MY6 A;  2RGN B;  2OQB A;  1DDM A;  3QBV B;  1FGZ A;  1Y19 B;  1FOE A;  2MKR A;  2YS5 A;  5C16 A;  1I2H A;  4F7G A;  2GJY A;  2D9X A;  4TYZ A;  5LON B;  4A6F B;  4NY0 A;  3D8D A;  2HTH B;  3PEG A;  5GOW B;  1X86 A;  1OMW A;  2H7E A;  2D9W A;  4IFS A;  1FHW A;  3P6A A;  4Z2M B;  2NMB A;  2KGX B;  4ZRI A;  4Z2N A;  5EFX A;  1RJ2 A;  2DYQ A;  1SHC A;  2PZ1 A;  2Z0P A;  2YT1 A;  1FAO A;  5HE0 A;  2P0H A;  1U5F A;  2ADZ A;  1NTV A;  3SO6 A;  1LB1 A;  3TVV A;  3ML4 A;  3VIA A;  3U8Z A;  2KUP A;  1UPR A;  4HAV B;  2RVB B;  2P0D A;  4GMV A;  3RCP A;  1H4R A;  4PQ0 A;  2N0Y A;  2CY5 A;  1V5M A;  1Y5O A;  1X05 A;  1TQZ A;  5LOP B;  1P6S A;  1XCG A;  3CXB B;  3KY9 A;  2W2X C;  2D2Q A;  2X18 A;  1MIX A;  4A6K A;  4IOY X;  2EMT A;  3D8E A;  2Q13 A;  1N3H A;  1U5G A;  1TJ6 A;  3OAN A;  3SV1 A;  4GN1 A;  2R0D A;  2CY4 A;  1PFJ A;  1DDV A;  2L2I A;  3SUZ A;  3PP2 A;  2J0M A;  5HE2 A;  1TXD A;  4Y94 A;  1NI2 A;  2G35 A;  1M7R A;  2J0K A;  4CYE A;  2MWN B;  2CRF A;  2LG1 A;  1RRP B;  2UVM A;  5DHA B;  4WVF B;  1K5G B;  1DRO A;  2ELA A;  5C5B A;  4PNK A;  4F7H A;  4HAX B;  2K00 A;  1PMS A;  1WG7 A;  2LKO A;  2LOX A;  2MDX A;  2YS3 A;  2UZS A;  4HDO A;  1ZC4 B;  4ZRK A;  4BBK A;  1FHX A;  2YF0 A;  1U5E A;  3A8Q A;  1WGU A;  3HK0 A;  2I1J A;  4HAZ B;  3M1I B;  2W2W A;  5DI9 B;  2RSG A;  1BAK A;  3WYF B;  4EJN A;  4F7U P;  3AU4 A;  4TKN A;  1V5U A;  1FB8 A;  2D4Q A;  2CAY A;  2J0J A;  4HAW B;  4KHA A;  1MIZ B;  4YL8 A;  3PG7 A;  4GPT B;  1ZC3 B;  5KQ4 A;  4HB0 B;  1X1F A;  5D3X A;  1H10 A;  1MAI A;  3TO1 A;  3TW1 A;  2NZ8 B;  2GCL A;  2D9Z A;  2DHI A;  4EKU A;  2K2U A;  1WVH A;  4HB4 B;  1UNQ A;  1GG3 A;  2VKI A;  4B6H A;  3F5R A;  2LOZ A;  4WJ7 A;  3CIK A;  1NTY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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