1H10A

High resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to ins(1,3,4,5)-tetrakisphophate
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
117
structure length
117
Chain Sequence
SMSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High Resolution Structure of the Pleckstrin Homology Domain of Protein Kinase B/Akt Bound to Phosphatidylinositol (3,4,5)-Trisphosphate
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords RAC-ALPHA SERINE/THREONINE KINASE
total genus 29
structure length 117
sequence length 117
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2002-07-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1h10A00
4TYZA 3RCPA 2D9ZA 1U5EA 2K2JA 1OQNA 4ZRJA 3G9WA 4WJ7A 4WSFA 1X1GA 2VKIA 4L6EA 5HE0A 1U2BA 2QKMA 2FJLA 4KHOA 1GC7A 1GC6A 1RRPB 5FI0A 2I1KA 2UVMA 2P0DA 5D3VA 3OANA 2M14A 1SGHA 3DXEA 1XD4A 1U27A 1P5TA 1QC6A 1UNRA 4K2OA 2J59M 3TFMA 2H7EA 3PZDA 1WVHA 2DKQA 2EC1A 1BWNA 2D4QA 3VIAA 1LB1A 1DDWA 1TJ6A 3ML4A 3PEGA 4TKNA 2EJ8A 1AWEA 4IFSA 1KI1B 1Z87A 2DKPA 2GJYA 1V5MA 1W1GA 2HE7A 5J3TA 1NI2A 2ROZB 2N23A 3BJIA 2KCJA 2GS0A 1PMSA 4HB0B 4K17A 4MY6A 1P3RA 2EMTA 1I2HA 5DIFB 4DX90 2COFA 4MT7A 1UEFA 1MK9B 2R09A 1MKEA 3ODOA 2L1CA 2YSZA 4P7IA 2D9XA 1I7AA 1PFJA 1TQZA 2ELAA 1ZM0A 5FI1A 3TVVA 5DH9B 4Z2NA 2KUPA 4MK0A 4ZRIA 5DI9B 3KRWA 4IOYX 1H10A 2VSZA 1GG3A 3F0WA 4ZRKA 3V5WA 1FHOA 3P6AA 1B55A 3LJUX 2NMBA 5D3XA 2D2QA 3A8PA 5HE3A 3ODXA 1UNPA 3HW2B 1PLSA 2OQBA 4D0NB 1W1HA 4Y94A 3HK0A 2I5CA 2CODA 2I5FA 2YS1A 4KHAA 2J0KA 1ZC4B 3DXDA 3SUZA 1K5GB 4GZUA 2LKOA 2D10A 2RGNB 3A8QA 2VRWB 1XKEA 5L81A 2PZ1A 1NTVA 2R0DA 2DHJA 5LOPB 2J0MA 1SHCA 1U5FA 2K2UA 1UPQA 1WGQA 4NSWA 4HB4B 1FHWA 2YF0A 3D8EA 4HB3B 2MDXA 2G35A 2J0JA 2K00A 2RVBB 4NY0A 2DX5A 1KZ7A 1KZGA 4A6FB 5C6RA 1U5DA 2NZ8B 1V88A 4HAVB 2LYDA 2BCJA 2D9YA 2P8VA 4F7UP 2EMSA 2W2XD 3PG7A 3T06A 2I1JA 3SNHA 5C16A 5D3WA 2OTXA 2ELBA 2AL6A 5JP4A 4PQ0A 4BBKA 3TO1A 3P7ZA 2L2IA 1FGZA 3QBVB 2KGXB 1DDMA 4IAPA 2DHIA 1EVHA 2E2XA 2N0YA 1U5GA 1K5DB 1XR0B 2GCLA 3ZVRA 4HAUB 3KRXA 4YL8A 4K2PA 4B6HA 2COCA 5C5BA 2Z0PA 5KCVA 4F7GA 2IYBA 5GOWB 2GCJA 1V61A 2MKRA 2YVCA 4GMXB 1EAZA 1RJ2A 2DYNA 1AQCA 2DHKA 3FM8C 2D9WA 1BAKA 5KQ4A 4A6HA 3PSCA 4GN1A 5KQ1A 3QIJA 4HATB 2CAYA 1M7EA 3SV1A 5EFXA 2XQNM 3PVWA 1W1DA 1Y19B 5LONB 2DTCA 1J0WA 1LW3A 2CRFA 2MFQA 4HHVA 1X1FA 3HQCA 4HAXB 2DLWA 2CY5A 1N3HA 3AU5A 1EGXA 2M38A 2Y8GA 5DHFB 2COAA 2W2XC 2RUKB 4DXAB 4H8SA 5JHGA 4CYEA 1XCGA 1X11A 4Z2MB 2V76A 2DA0A 1X86A 3TW1A 2X18A 2JP2A 5D27A 2DX1A 2YS3A 3CXBB 1X05A 4C0AA 3O96A 4K81A 4DX8A 1M7RA 4A6FA 4GMVA 2DN6A 4HAZB 5J3QA 2CY4A 3TCAA 2UZRA 2HTHB 4EMOA 3SYXA 3MPXA 5JHHA 3U8ZA 3UZTA 5HE1A 2RLOA 1MIZB 1QQGA 1V5PA 4DBBA 1ISNA 2W2WA 1WI1A 2DFKA 1MAIA 5HE2A 1FHXA 4F7HA 2UZSA 1Y5OA 1UPRA 1FGYA 3N7CA 2IFSA 3IVFA 3QWMA 2MWNB 4KHBB 1ZSQA 4CHMA 3A98B 1WG7A 4GPTB 3NSUA 4HDQA 2LULA 3AJ4A 3ODWA 2Y7BA 2Z0QA 1DYNA 1DROA 1TXDA 1BTNA 2ZPYA 3PP2A 2ROVA 2LG1A 1WJMA 2AEHA 1E5WA 3DXCA 4HDOA 2LOZA 2ADZA 3ULCA 1FB8A 3PVUA 3BINA 5J3YA 1MPHA 4A6KA 1WGUA 3GYPA 2H7DA 4HB2B 3KSYA 5DHAB 5CLQB 1FOEA 1V5UA 1WJ1A 1MIXA 3U7DA 1DDVA 1BTKA 3SO6A 1ZVRA 4HAYB 5D3YA 4KVGB 3FEHA 2YT1A 5CLLB 3PVLA 1NTYA 2RSGA 4EKUA 2P0HA 3D8FA 3KZ1A 3WA0A 3X23A 2D11A 1H4RA 5JLJB 4EJNA 4KAXB 5C5BB 2P0FA 4WVFB 1OMWA 3WYFB 1MK7B 3CIKA 2RNRB 2YRYA 2Q13A 2DYQA 4GXBA 5C79A 1J19A 1IRSA 3M1IB 2D9VA 4XWXA 1P6SA 2QKLA 1Q67A 1DBHA 4PNKA 1OY2A 2Z0OA 4A5KA 3GYOA 2YS5A 4YONA 3MDBC 2Y8FA 1FAOA 3F5RA 3D8DA 1V89A 1NU2A 3AU4A 3ULBA 3VOQA 1ZC3B 1U29A 1EF1A 3ZDTA 3KY9A 4CHJA 1UNQA 1XX0A 2YT0A 3FSSA 2LOXA 1XODA 4HAWB
chains in the Genus database with same CATH superfamily
4TYZA 3RCPA 2D9ZA 1U5EA 2K2JA 1OQNA 4ZRJA 3G9WA 4WJ7A 4WSFA 1X1GA 2VKIA 4CSQA 4L6EA 5HE0A 1U2BA 2QKMA 2FJLA 4KHOA 1GC7A 1GC6A 1RRPB 2ZKMX 5FI0A 2I1KA 2UVMA 2P0DA 5D3VA 3OANA 2M14A 1SGHA 3DXEA 1XD4A 1U27A 2KR0A 1P5TA 4GOUA 1QC6A 1UNRA 4K2OA 2J59M 3TFMA 2H7EA 2YT2A 3PZDA 4QJ5B 2Z13A 1WVHA 2DKQA 2EC1A 1BWNA 2D4QA 3VIAA 1LB1A 1DDWA 1TJ6A 3DCXA 3ML4A 4OT1A 3PEGA 4TKNA 2EJ8A 1AWEA 4IFSA 1KI1B 1Z87A 2DKPA 2GJYA 1V5MA 1W1GA 2HE7A 5J3TA 1NI2A 2ROZB 2N23A 3BJIA 2KCJA 2GS0A 1PMSA 2FJUB 2GUMA 4HB0B 4K17A 4MY6A 1P3RA 2EMTA 1I2HA 2R2YA 5DIFB 2KIGA 4DX90 2COFA 4MT7A 1UEFA 1MK9B 2R09A 1MKEA 3ODOA 2L1CA 2YSZA 4P7IA 2D9XA 1I7AA 1PFJA 1TQZA 2ELAA 1ZM0A 5FI1A 3TVVA 5DH9B 4Z2NA 2KUPA 4MK0A 4ZRIA 5DI9B 3KRWA 4IOYX 2K8EA 1H10A 2VSZA 1GG3A 3F0WA 4ZRKA 3V5WA 1FHOA 3P6AA 1B55A 3LJUX 2NMBA 5D3XA 2D2QA 3A8PA 5HE3A 3ODXA 1UNPA 3HW2B 1PLSA 4D6WA 2OQBA 4D0NB 1W1HA 4Y94A 3HK0A 2I5CA 2CODA 2I5FA 2YS1A 4KHAA 2J0KA 1ZC4B 3DXDA 3SUZA 1K5GB 4GZUA 2LKOA 2D10A 2RGNB 3A8QA 2VRWB 1XKEA 4KHBA 5L81A 2PZ1A 1NTVA 2R0DA 2DHJA 5LOPB 2J0MA 1SHCA 1U5FA 2K2UA 1UPQA 1WGQA 4NSWA 4HB4B 1FHWA 2YF0A 3D8EA 4HB3B 2MDXA 2G35A 2J0JA 2K00A 2RVBB 4NY0A 2DX5A 1KZ7A 1KZGA 4A6FB 3U12A 5C6RA 5I2SA 1U5DA 2NZ8B 1V88A 4HAVB 2LYDA 2BCJA 4QXAB 2D9YA 2P8VA 4F7UP 2EMSA 2W2XD 3PG7A 3T06A 2I1JA 3SNHA 5C16A 5D3WA 2OTXA 2ELBA 2AL6A 5JP4A 5IRSA 4PQ0A 4BBKA 3TO1A 3P7ZA 2L2IA 1FGZA 3QBVB 2KGXB 1DDMA 4IAPA 2DHIA 1EVHA 3NWAA 2E2XA 2N0YA 1U5GA 1K5DB 1XR0B 2GCLA 3ZVRA 4HAUB 3KRXA 4YL8A 4K2PA 4B6HA 1ZYIA 2COCA 5C5BA 2Z0PA 1MI1A 5KCVA 4F7GA 2IYBA 5GOWB 2GCJA 1V61A 2MKRA 2YVCA 4OSNA 4GMXB 1EAZA 1RJ2A 2NBVA 2DYNA 1AQCA 2DHKA 3FM8C 2KUQA 2D9WA 1BAKA 5KQ4A 4A6HA 3PSCA 4GN1A 3NW8A 5KQ1A 3QIJA 4HATB 5LG4B 2CAYA 1M7EA 3SV1A 5EFXA 2XQNM 3PVWA 1W1DA 1Y19B 5LONB 2DTCA 1J0WA 1LW3A 3A58A 2CRFA 2MFQA 4HHVA 1X1FA 3HQCA 4HAXB 2DLWA 3HIEA 2CY5A 4QJ3B 3AU5A 1N3HA 1EGXA 2M38A 2Y8GA 5DHFB 2COAA 2W2XC 2RUKB 2Z4DA 4DXAB 4H8SA 5JHGA 4CYEA 1XCGA 1X11A 4Z2MB 2V76A 2DA0A 1X86A 3TW1A 2X18A 2JP2A 5D27A 2DX1A 2YS3A 3CXBB 1X05A 4C0AA 3O96A 4K81A 4DX8A 1M7RA 4A6FA 4GMVA 2DN6A 4HAZB 5J3QA 2CY4A 3TCAA 2UZRA 2HTHB 4EMOA 3SYXA 3MPXA 5JHHA 3U8ZA 3UZTA 5HE1A 2RLOA 1MIZB 1QQGA 3NWFA 1V5PA 4DBBA 1ISNA 2W2WA 1WI1A 2DFKA 1MAIA 5HE2A 1FHXA 4F7HA 2UZSA 1Y5OA 1UPRA 1FGYA 3N7CA 2IFSA 3IVFA 3QWMA 2MWNB 4KHBB 1ZSQA 4CHMA 3A98B 1WG7A 4GPTB 3NSUA 4HDQA 2LULA 3AJ4A 3ODWA 2Y7BA 2Z0QA 1DYNA 1DROA 1TXDA 1BTNA 2ZPYA 2Z59A 3PP2A 2ROVA 2LG1A 1WJMA 2AEHA 1E5WA 3DXCA 4HDOA 2LOZA 2ADZA 3ULCA 1FB8A 2Z14A 3PVUA 3BINA 5I2MA 4DIXA 5J3YA 1MPHA 4A6KA 4GNKB 1WGUA 3GYPA 4HSIA 2H7DA 4HB2B 3KSYA 5DHAB 5CLQB 1FOEA 1V5UA 1WJ1A 1MIXA 3U7DA 1DDVA 1BTKA 2K49A 3SO6A 1ZVRA 4HAYB 5D3YA 3OHMB 4L1RA 4KVGB 3FEHA 2YT1A 5M4YB 5CLLB 3PVLA 1NTYA 4QJ4B 2RSGA 4EKUA 2P0HA 2KIEA 3D8FA 3KZ1A 3WA0A 3X23A 3HSAA 2D11A 1H4RA 5JLJB 4EJNA 4KAXB 5C5BB 2P0FA 4WVFB 1OMWA 3WYFB 1MK7B 3CIKA 2RNRB 2YRYA 2Q13A 2DYQA 4GXBA 2RRFA 5C79A 1J19A 1IRSA 3M1IB 2D9VA 4XWXA 1P6SA 2QKLA 1Q67A 1DBHA 4PNKA 1OY2A 2Z0OA 4A5KA 3NWDA 3B77A 3GYOA 2YS5A 4YONA 3MDBC 2Y8FA 1FAOA 3F5RA 3D8DA 1V89A 1NU2A 3AU4A 3ULBA 3VOQA 1T77A 1ZC3B 1U29A 1EF1A 3ZDTA 3KY9A 4CHJA 1UNQA 1XX0A 2YT0A 3FSSA 2LOXA 1XODA 3FVCA 4HAWB
chains in the Genus database with same CATH topology
4TYZA 3RCPA 2D9ZA 1U5EA 2K2JA 1OQNA 4ZRJA 3G9WA 4WJ7A 4WSFA 1X1GA 2VKIA 4L6EA 5HE0A 1U2BA 2QKMA 2FJLA 4KHOA 1GC7A 1GC6A 1RRPB 5FI0A 2I1KA 2UVMA 2P0DA 5D3VA 3OANA 2M14A 1SGHA 3DXEA 1XD4A 1U27A 1P5TA 1QC6A 1UNRA 4K2OA 2J59M 3TFMA 2H7EA 3PZDA 1WVHA 2DKQA 2EC1A 1BWNA 2D4QA 3VIAA 1LB1A 1DDWA 1TJ6A 3ML4A 3PEGA 4TKNA 2EJ8A 1AWEA 4IFSA 1KI1B 1Z87A 2DKPA 2GJYA 1V5MA 1W1GA 2HE7A 5J3TA 1NI2A 2ROZB 2N23A 3BJIA 2KCJA 2GS0A 1PMSA 4HB0B 4K17A 4MY6A 1P3RA 2EMTA 1I2HA 5DIFB 4DX90 2COFA 4MT7A 1UEFA 1MK9B 2R09A 1MKEA 3ODOA 2L1CA 2YSZA 4P7IA 2D9XA 1I7AA 1PFJA 1TQZA 2ELAA 1ZM0A 5FI1A 3TVVA 5DH9B 4Z2NA 2KUPA 4MK0A 4ZRIA 5DI9B 3KRWA 4IOYX 1H10A 2VSZA 1GG3A 3F0WA 4ZRKA 3V5WA 1FHOA 3P6AA 1B55A 3LJUX 2NMBA 5D3XA 2D2QA 3A8PA 5HE3A 3ODXA 1UNPA 3HW2B 1PLSA 2OQBA 4D0NB 1W1HA 4Y94A 3HK0A 2I5CA 2CODA 2I5FA 2YS1A 4KHAA 2J0KA 1ZC4B 3DXDA 3SUZA 1K5GB 4GZUA 2LKOA 2D10A 2RGNB 3A8QA 2VRWB 1XKEA 5L81A 2PZ1A 1NTVA 2R0DA 2DHJA 5LOPB 2J0MA 1SHCA 1U5FA 2K2UA 1UPQA 1WGQA 4NSWA 4HB4B 1FHWA 2YF0A 3D8EA 4HB3B 2MDXA 2G35A 2J0JA 2K00A 2RVBB 4NY0A 2DX5A 1KZ7A 1KZGA 4A6FB 5C6RA 1U5DA 2NZ8B 1V88A 4HAVB 2LYDA 2BCJA 2D9YA 2P8VA 4F7UP 2EMSA 2W2XD 3PG7A 3T06A 2I1JA 3SNHA 5C16A 5D3WA 2OTXA 2ELBA 2AL6A 5JP4A 4PQ0A 4BBKA 3TO1A 3P7ZA 2L2IA 1FGZA 3QBVB 2KGXB 1DDMA 4IAPA 2DHIA 1EVHA 2E2XA 2N0YA 1U5GA 1K5DB 1XR0B 2GCLA 3ZVRA 4HAUB 3KRXA 4YL8A 4K2PA 4B6HA 2COCA 5C5BA 2Z0PA 5KCVA 4F7GA 2IYBA 5GOWB 2GCJA 1V61A 2MKRA 2YVCA 4GMXB 1EAZA 1RJ2A 2DYNA 1AQCA 2DHKA 3FM8C 2D9WA 1BAKA 5KQ4A 4A6HA 3PSCA 4GN1A 5KQ1A 3QIJA 4HATB 2CAYA 1M7EA 3SV1A 5EFXA 2XQNM 3PVWA 1W1DA 1Y19B 5LONB 2DTCA 1J0WA 1LW3A 2CRFA 2MFQA 4HHVA 1X1FA 3HQCA 4HAXB 2DLWA 2CY5A 1N3HA 3AU5A 1EGXA 2M38A 2Y8GA 5DHFB 2COAA 2W2XC 2RUKB 4DXAB 4H8SA 5JHGA 4CYEA 1XCGA 1X11A 4Z2MB 2V76A 2DA0A 1X86A 3TW1A 2X18A 2JP2A 5D27A 2DX1A 2YS3A 3CXBB 1X05A 4C0AA 3O96A 4K81A 4DX8A 1M7RA 4A6FA 4GMVA 2DN6A 4HAZB 5J3QA 2CY4A 3TCAA 2UZRA 2HTHB 4EMOA 3SYXA 3MPXA 5JHHA 3U8ZA 3UZTA 5HE1A 2RLOA 1MIZB 1QQGA 1V5PA 4DBBA 1ISNA 2W2WA 1WI1A 2DFKA 1MAIA 5HE2A 1FHXA 4F7HA 2UZSA 1Y5OA 1UPRA 1FGYA 3N7CA 2IFSA 3IVFA 3QWMA 2MWNB 4KHBB 1ZSQA 4CHMA 3A98B 1WG7A 4GPTB 3NSUA 4HDQA 2LULA 3AJ4A 3ODWA 2Y7BA 2Z0QA 1DYNA 1DROA 1TXDA 1BTNA 2ZPYA 3PP2A 2ROVA 2LG1A 1WJMA 2AEHA 1E5WA 3DXCA 4HDOA 2LOZA 2ADZA 3ULCA 1FB8A 3PVUA 3BINA 5J3YA 1MPHA 4A6KA 1WGUA 3GYPA 2H7DA 4HB2B 3KSYA 5DHAB 5CLQB 1FOEA 1V5UA 1WJ1A 1MIXA 3U7DA 1DDVA 1BTKA 3SO6A 1ZVRA 4HAYB 5D3YA 4KVGB 3FEHA 2YT1A 5CLLB 3PVLA 1NTYA 2RSGA 4EKUA 2P0HA 3D8FA 3KZ1A 3WA0A 3X23A 2D11A 1H4RA 5JLJB 4EJNA 4KAXB 5C5BB 2P0FA 4WVFB 1OMWA 3WYFB 1MK7B 3CIKA 2RNRB 2YRYA 2Q13A 2DYQA 4GXBA 5C79A 1J19A 1IRSA 3M1IB 2D9VA 4XWXA 1P6SA 2QKLA 1Q67A 1DBHA 4PNKA 1OY2A 2Z0OA 4A5KA 3GYOA 2YS5A 4YONA 3MDBC 2Y8FA 1FAOA 3F5RA 3D8DA 1V89A 1NU2A 3AU4A 3ULBA 3VOQA 1ZC3B 1U29A 1EF1A 3ZDTA 3KY9A 4CHJA 1UNQA 1XX0A 2YT0A 3FSSA 2LOXA 1XODA 4HAWB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TYZ A;  3RCP A;  2D9Z A;  1U5E A;  2K2J A;  1OQN A;  4ZRJ A;  3G9W A;  4WJ7 A;  4WSF A;  1X1G A;  2VKI A;  4L6E A;  5HE0 A;  1U2B A;  2QKM A;  2FJL A;  4KHO A;  1GC7 A;  1GC6 A;  1RRP B;  5FI0 A;  2I1K A;  2UVM A;  2P0D A;  5D3V A;  3OAN A;  2M14 A;  1SGH A;  3DXE A;  1XD4 A;  1U27 A;  1P5T A;  1QC6 A;  1UNR A;  4K2O A;  2J59 M;  3TFM A;  2H7E A;  3PZD A;  1WVH A;  2DKQ A;  2EC1 A;  1BWN A;  2D4Q A;  3VIA A;  1LB1 A;  1DDW A;  1TJ6 A;  3ML4 A;  3PEG A;  4TKN A;  2EJ8 A;  1AWE A;  4IFS A;  1KI1 B;  1Z87 A;  2DKP A;  2GJY A;  1V5M A;  1W1G A;  2HE7 A;  5J3T A;  1NI2 A;  2ROZ B;  2N23 A;  3BJI A;  2KCJ A;  2GS0 A;  1PMS A;  4HB0 B;  4K17 A;  4MY6 A;  1P3R A;  2EMT A;  1I2H A;  5DIF B;  4DX9 0;  2COF A;  4MT7 A;  1UEF A;  1MK9 B;  2R09 A;  1MKE A;  3ODO A;  2L1C A;  2YSZ A;  4P7I A;  2D9X A;  1I7A A;  1PFJ A;  1TQZ A;  2ELA A;  1ZM0 A;  5FI1 A;  3TVV A;  5DH9 B;  4Z2N A;  2KUP A;  4MK0 A;  4ZRI A;  5DI9 B;  3KRW A;  4IOY X;  1H10 A;  2VSZ A;  1GG3 A;  3F0W A;  4ZRK A;  3V5W A;  1FHO A;  3P6A A;  1B55 A;  3LJU X;  2NMB A;  5D3X A;  2D2Q A;  3A8P A;  5HE3 A;  3ODX A;  1UNP A;  3HW2 B;  1PLS A;  2OQB A;  4D0N B;  1W1H A;  4Y94 A;  3HK0 A;  2I5C A;  2COD A;  2I5F A;  2YS1 A;  4KHA A;  2J0K A;  1ZC4 B;  3DXD A;  3SUZ A;  1K5G B;  4GZU A;  2LKO A;  2D10 A;  2RGN B;  3A8Q A;  2VRW B;  1XKE A;  5L81 A;  2PZ1 A;  1NTV A;  2R0D A;  2DHJ A;  5LOP B;  2J0M A;  1SHC A;  1U5F A;  2K2U A;  1UPQ A;  1WGQ A;  4NSW A;  4HB4 B;  1FHW A;  2YF0 A;  3D8E A;  4HB3 B;  2MDX A;  2G35 A;  2J0J A;  2K00 A;  2RVB B;  4NY0 A;  2DX5 A;  1KZ7 A;  1KZG A;  4A6F B;  5C6R A;  1U5D A;  2NZ8 B;  1V88 A;  4HAV B;  2LYD A;  2BCJ A;  2D9Y A;  2P8V A;  4F7U P;  2EMS A;  2W2X D;  3PG7 A;  3T06 A;  2I1J A;  3SNH A;  5C16 A;  5D3W A;  2OTX A;  2ELB A;  2AL6 A;  5JP4 A;  4PQ0 A;  4BBK A;  3TO1 A;  3P7Z A;  2L2I A;  1FGZ A;  3QBV B;  2KGX B;  1DDM A;  4IAP A;  2DHI A;  1EVH A;  2E2X A;  2N0Y A;  1U5G A;  1K5D B;  1XR0 B;  2GCL A;  3ZVR A;  4HAU B;  3KRX A;  4YL8 A;  4K2P A;  4B6H A;  2COC A;  5C5B A;  2Z0P A;  5KCV A;  4F7G A;  2IYB A;  5GOW B;  2GCJ A;  1V61 A;  2MKR A;  2YVC A;  4GMX B;  1EAZ A;  1RJ2 A;  2DYN A;  1AQC A;  2DHK A;  3FM8 C;  2D9W A;  1BAK A;  5KQ4 A;  4A6H A;  3PSC A;  4GN1 A;  5KQ1 A;  3QIJ A;  4HAT B;  2CAY A;  1M7E A;  3SV1 A;  5EFX A;  2XQN M;  3PVW A;  1W1D A;  1Y19 B;  5LON B;  2DTC A;  1J0W A;  1LW3 A;  2CRF A;  2MFQ A;  4HHV A;  1X1F A;  3HQC A;  4HAX B;  2DLW A;  2CY5 A;  1N3H A;  3AU5 A;  1EGX A;  2M38 A;  2Y8G A;  5DHF B;  2COA A;  2W2X C;  2RUK B;  4DXA B;  4H8S A;  5JHG A;  4CYE A;  1XCG A;  1X11 A;  4Z2M B;  2V76 A;  2DA0 A;  1X86 A;  3TW1 A;  2X18 A;  2JP2 A;  5D27 A;  2DX1 A;  2YS3 A;  3CXB B;  1X05 A;  4C0A A;  3O96 A;  4K81 A;  4DX8 A;  1M7R A;  4A6F A;  4GMV A;  2DN6 A;  4HAZ B;  5J3Q A;  2CY4 A;  3TCA A;  2UZR A;  2HTH B;  4EMO A;  3SYX A;  3MPX A;  5JHH A;  3U8Z A;  3UZT A;  5HE1 A;  2RLO A;  1MIZ B;  1QQG A;  1V5P A;  4DBB A;  1ISN A;  2W2W A;  1WI1 A;  2DFK A;  1MAI A;  5HE2 A;  1FHX A;  4F7H A;  2UZS A;  1Y5O A;  1UPR A;  1FGY A;  3N7C A;  2IFS A;  3IVF A;  3QWM A;  2MWN B;  4KHB B;  1ZSQ A;  4CHM A;  3A98 B;  1WG7 A;  4GPT B;  3NSU A;  4HDQ A;  2LUL A;  3AJ4 A;  3ODW A;  2Y7B A;  2Z0Q A;  1DYN A;  1DRO A;  1TXD A;  1BTN A;  2ZPY A;  3PP2 A;  2ROV A;  2LG1 A;  1WJM A;  2AEH A;  1E5W A;  3DXC A;  4HDO A;  2LOZ A;  2ADZ A;  3ULC A;  1FB8 A;  3PVU A;  3BIN A;  5J3Y A;  1MPH A;  4A6K A;  1WGU A;  3GYP A;  2H7D A;  4HB2 B;  3KSY A;  5DHA B;  5CLQ B;  1FOE A;  1V5U A;  1WJ1 A;  1MIX A;  3U7D A;  1DDV A;  1BTK A;  3SO6 A;  1ZVR A;  4HAY B;  5D3Y A;  4KVG B;  3FEH A;  2YT1 A;  5CLL B;  3PVL A;  1NTY A;  2RSG A;  4EKU A;  2P0H A;  3D8F A;  3KZ1 A;  3WA0 A;  3X23 A;  2D11 A;  1H4R A;  5JLJ B;  4EJN A;  4KAX B;  5C5B B;  2P0F A;  4WVF B;  1OMW A;  3WYF B;  1MK7 B;  3CIK A;  2RNR B;  2YRY A;  2Q13 A;  2DYQ A;  4GXB A;  5C79 A;  1J19 A;  1IRS A;  3M1I B;  2D9V A;  4XWX A;  1P6S A;  2QKL A;  1Q67 A;  1DBH A;  4PNK A;  1OY2 A;  2Z0O A;  4A5K A;  3GYO A;  2YS5 A;  4YON A;  3MDB C;  2Y8F A;  1FAO A;  3F5R A;  3D8D A;  1V89 A;  1NU2 A;  3AU4 A;  3ULB A;  3VOQ A;  1ZC3 B;  1U29 A;  1EF1 A;  3ZDT A;  3KY9 A;  4CHJ A;  1UNQ A;  1XX0 A;  2YT0 A;  3FSS A;  2LOX A;  1XOD A;  4HAW B; 
#chains in the Genus database with same CATH topology
 4TYZ A;  3RCP A;  2D9Z A;  1U5E A;  2K2J A;  1OQN A;  4ZRJ A;  3G9W A;  4WJ7 A;  4WSF A;  1X1G A;  2VKI A;  4CSQ A;  4L6E A;  5HE0 A;  1U2B A;  2QKM A;  2FJL A;  4KHO A;  1GC7 A;  1GC6 A;  1RRP B;  2ZKM X;  5FI0 A;  2I1K A;  2UVM A;  2P0D A;  5D3V A;  3OAN A;  2M14 A;  1SGH A;  3DXE A;  1XD4 A;  1U27 A;  2KR0 A;  1P5T A;  4GOU A;  1QC6 A;  1UNR A;  4K2O A;  2J59 M;  3TFM A;  2H7E A;  2YT2 A;  3PZD A;  4QJ5 B;  2Z13 A;  1WVH A;  2DKQ A;  2EC1 A;  1BWN A;  2D4Q A;  3VIA A;  1LB1 A;  1DDW A;  1TJ6 A;  3DCX A;  3ML4 A;  4OT1 A;  3PEG A;  4TKN A;  2EJ8 A;  1AWE A;  4IFS A;  1KI1 B;  1Z87 A;  2DKP A;  2GJY A;  1V5M A;  1W1G A;  2HE7 A;  5J3T A;  1NI2 A;  2ROZ B;  2N23 A;  3BJI A;  2KCJ A;  2GS0 A;  1PMS A;  2FJU B;  2GUM A;  4HB0 B;  4K17 A;  4MY6 A;  1P3R A;  2EMT A;  1I2H A;  2R2Y A;  5DIF B;  2KIG A;  4DX9 0;  2COF A;  4MT7 A;  1UEF A;  1MK9 B;  2R09 A;  1MKE A;  3ODO A;  2L1C A;  2YSZ A;  4P7I A;  2D9X A;  1I7A A;  1PFJ A;  1TQZ A;  2ELA A;  1ZM0 A;  5FI1 A;  3TVV A;  5DH9 B;  4Z2N A;  2KUP A;  4MK0 A;  4ZRI A;  5DI9 B;  3KRW A;  4IOY X;  2K8E A;  1H10 A;  2VSZ A;  1GG3 A;  3F0W A;  4ZRK A;  3V5W A;  1FHO A;  3P6A A;  1B55 A;  3LJU X;  2NMB A;  5D3X A;  2D2Q A;  3A8P A;  5HE3 A;  3ODX A;  1UNP A;  3HW2 B;  1PLS A;  4D6W A;  2OQB A;  4D0N B;  1W1H A;  4Y94 A;  3HK0 A;  2I5C A;  2COD A;  2I5F A;  2YS1 A;  4KHA A;  2J0K A;  1ZC4 B;  3DXD A;  3SUZ A;  1K5G B;  4GZU A;  2LKO A;  2D10 A;  2RGN B;  3A8Q A;  2VRW B;  1XKE A;  4KHB A;  5L81 A;  2PZ1 A;  1NTV A;  2R0D A;  2DHJ A;  5LOP B;  2J0M A;  1SHC A;  1U5F A;  2K2U A;  1UPQ A;  1WGQ A;  4NSW A;  4HB4 B;  1FHW A;  2YF0 A;  3D8E A;  4HB3 B;  2MDX A;  2G35 A;  2J0J A;  2K00 A;  2RVB B;  4NY0 A;  2DX5 A;  1KZ7 A;  1KZG A;  4A6F B;  3U12 A;  5C6R A;  5I2S A;  1U5D A;  2NZ8 B;  1V88 A;  4HAV B;  2LYD A;  2BCJ A;  4QXA B;  2D9Y A;  2P8V A;  4F7U P;  2EMS A;  2W2X D;  3PG7 A;  3T06 A;  2I1J A;  3SNH A;  5C16 A;  5D3W A;  2OTX A;  2ELB A;  2AL6 A;  5JP4 A;  5IRS A;  4PQ0 A;  4BBK A;  3TO1 A;  3P7Z A;  2L2I A;  1FGZ A;  3QBV B;  2KGX B;  1DDM A;  4IAP A;  2DHI A;  1EVH A;  3NWA A;  2E2X A;  2N0Y A;  1U5G A;  1K5D B;  1XR0 B;  2GCL A;  3ZVR A;  4HAU B;  3KRX A;  4YL8 A;  4K2P A;  4B6H A;  1ZYI A;  2COC A;  5C5B A;  2Z0P A;  1MI1 A;  5KCV A;  4F7G A;  2IYB A;  5GOW B;  2GCJ A;  1V61 A;  2MKR A;  2YVC A;  4OSN A;  4GMX B;  1EAZ A;  1RJ2 A;  2NBV A;  2DYN A;  1AQC A;  2DHK A;  3FM8 C;  2KUQ A;  2D9W A;  1BAK A;  5KQ4 A;  4A6H A;  3PSC A;  4GN1 A;  3NW8 A;  5KQ1 A;  3QIJ A;  4HAT B;  5LG4 B;  2CAY A;  1M7E A;  3SV1 A;  5EFX A;  2XQN M;  3PVW A;  1W1D A;  1Y19 B;  5LON B;  2DTC A;  1J0W A;  1LW3 A;  3A58 A;  2CRF A;  2MFQ A;  4HHV A;  1X1F A;  3HQC A;  4HAX B;  2DLW A;  3HIE A;  2CY5 A;  4QJ3 B;  3AU5 A;  1N3H A;  1EGX A;  2M38 A;  2Y8G A;  5DHF B;  2COA A;  2W2X C;  2RUK B;  2Z4D A;  4DXA B;  4H8S A;  5JHG A;  4CYE A;  1XCG A;  1X11 A;  4Z2M B;  2V76 A;  2DA0 A;  1X86 A;  3TW1 A;  2X18 A;  2JP2 A;  5D27 A;  2DX1 A;  2YS3 A;  3CXB B;  1X05 A;  4C0A A;  3O96 A;  4K81 A;  4DX8 A;  1M7R A;  4A6F A;  4GMV A;  2DN6 A;  4HAZ B;  5J3Q A;  2CY4 A;  3TCA A;  2UZR A;  2HTH B;  4EMO A;  3SYX A;  3MPX A;  5JHH A;  3U8Z A;  3UZT A;  5HE1 A;  2RLO A;  1MIZ B;  1QQG A;  3NWF A;  1V5P A;  4DBB A;  1ISN A;  2W2W A;  1WI1 A;  2DFK A;  1MAI A;  5HE2 A;  1FHX A;  4F7H A;  2UZS A;  1Y5O A;  1UPR A;  1FGY A;  3N7C A;  2IFS A;  3IVF A;  3QWM A;  2MWN B;  4KHB B;  1ZSQ A;  4CHM A;  3A98 B;  1WG7 A;  4GPT B;  3NSU A;  4HDQ A;  2LUL A;  3AJ4 A;  3ODW A;  2Y7B A;  2Z0Q A;  1DYN A;  1DRO A;  1TXD A;  1BTN A;  2ZPY A;  2Z59 A;  3PP2 A;  2ROV A;  2LG1 A;  1WJM A;  2AEH A;  1E5W A;  3DXC A;  4HDO A;  2LOZ A;  2ADZ A;  3ULC A;  1FB8 A;  2Z14 A;  3PVU A;  3BIN A;  5I2M A;  4DIX A;  5J3Y A;  1MPH A;  4A6K A;  4GNK B;  1WGU A;  3GYP A;  4HSI A;  2H7D A;  4HB2 B;  3KSY A;  5DHA B;  5CLQ B;  1FOE A;  1V5U A;  1WJ1 A;  1MIX A;  3U7D A;  1DDV A;  1BTK A;  2K49 A;  3SO6 A;  1ZVR A;  4HAY B;  5D3Y A;  3OHM B;  4L1R A;  4KVG B;  3FEH A;  2YT1 A;  5M4Y B;  5CLL B;  3PVL A;  1NTY A;  4QJ4 B;  2RSG A;  4EKU A;  2P0H A;  2KIE A;  3D8F A;  3KZ1 A;  3WA0 A;  3X23 A;  3HSA A;  2D11 A;  1H4R A;  5JLJ B;  4EJN A;  4KAX B;  5C5B B;  2P0F A;  4WVF B;  1OMW A;  3WYF B;  1MK7 B;  3CIK A;  2RNR B;  2YRY A;  2Q13 A;  2DYQ A;  4GXB A;  2RRF A;  5C79 A;  1J19 A;  1IRS A;  3M1I B;  2D9V A;  4XWX A;  1P6S A;  2QKL A;  1Q67 A;  1DBH A;  4PNK A;  1OY2 A;  2Z0O A;  4A5K A;  3NWD A;  3B77 A;  3GYO A;  2YS5 A;  4YON A;  3MDB C;  2Y8F A;  1FAO A;  3F5R A;  3D8D A;  1V89 A;  1NU2 A;  3AU4 A;  3ULB A;  3VOQ A;  1T77 A;  1ZC3 B;  1U29 A;  1EF1 A;  3ZDT A;  3KY9 A;  4CHJ A;  1UNQ A;  1XX0 A;  2YT0 A;  3FSS A;  2LOX A;  1XOD A;  3FVC A;  4HAW B; 
#chains in the Genus database with same CATH homology
 4TYZ A;  3RCP A;  2D9Z A;  1U5E A;  2K2J A;  1OQN A;  4ZRJ A;  3G9W A;  4WJ7 A;  4WSF A;  1X1G A;  2VKI A;  4L6E A;  5HE0 A;  1U2B A;  2QKM A;  2FJL A;  4KHO A;  1GC7 A;  1GC6 A;  1RRP B;  5FI0 A;  2I1K A;  2UVM A;  2P0D A;  5D3V A;  3OAN A;  2M14 A;  1SGH A;  3DXE A;  1XD4 A;  1U27 A;  1P5T A;  1QC6 A;  1UNR A;  4K2O A;  2J59 M;  3TFM A;  2H7E A;  3PZD A;  1WVH A;  2DKQ A;  2EC1 A;  1BWN A;  2D4Q A;  3VIA A;  1LB1 A;  1DDW A;  1TJ6 A;  3ML4 A;  3PEG A;  4TKN A;  2EJ8 A;  1AWE A;  4IFS A;  1KI1 B;  1Z87 A;  2DKP A;  2GJY A;  1V5M A;  1W1G A;  2HE7 A;  5J3T A;  1NI2 A;  2ROZ B;  2N23 A;  3BJI A;  2KCJ A;  2GS0 A;  1PMS A;  4HB0 B;  4K17 A;  4MY6 A;  1P3R A;  2EMT A;  1I2H A;  5DIF B;  4DX9 0;  2COF A;  4MT7 A;  1UEF A;  1MK9 B;  2R09 A;  1MKE A;  3ODO A;  2L1C A;  2YSZ A;  4P7I A;  2D9X A;  1I7A A;  1PFJ A;  1TQZ A;  2ELA A;  1ZM0 A;  5FI1 A;  3TVV A;  5DH9 B;  4Z2N A;  2KUP A;  4MK0 A;  4ZRI A;  5DI9 B;  3KRW A;  4IOY X;  1H10 A;  2VSZ A;  1GG3 A;  3F0W A;  4ZRK A;  3V5W A;  1FHO A;  3P6A A;  1B55 A;  3LJU X;  2NMB A;  5D3X A;  2D2Q A;  3A8P A;  5HE3 A;  3ODX A;  1UNP A;  3HW2 B;  1PLS A;  2OQB A;  4D0N B;  1W1H A;  4Y94 A;  3HK0 A;  2I5C A;  2COD A;  2I5F A;  2YS1 A;  4KHA A;  2J0K A;  1ZC4 B;  3DXD A;  3SUZ A;  1K5G B;  4GZU A;  2LKO A;  2D10 A;  2RGN B;  3A8Q A;  2VRW B;  1XKE A;  5L81 A;  2PZ1 A;  1NTV A;  2R0D A;  2DHJ A;  5LOP B;  2J0M A;  1SHC A;  1U5F A;  2K2U A;  1UPQ A;  1WGQ A;  4NSW A;  4HB4 B;  1FHW A;  2YF0 A;  3D8E A;  4HB3 B;  2MDX A;  2G35 A;  2J0J A;  2K00 A;  2RVB B;  4NY0 A;  2DX5 A;  1KZ7 A;  1KZG A;  4A6F B;  5C6R A;  1U5D A;  2NZ8 B;  1V88 A;  4HAV B;  2LYD A;  2BCJ A;  2D9Y A;  2P8V A;  4F7U P;  2EMS A;  2W2X D;  3PG7 A;  3T06 A;  2I1J A;  3SNH A;  5C16 A;  5D3W A;  2OTX A;  2ELB A;  2AL6 A;  5JP4 A;  4PQ0 A;  4BBK A;  3TO1 A;  3P7Z A;  2L2I A;  1FGZ A;  3QBV B;  2KGX B;  1DDM A;  4IAP A;  2DHI A;  1EVH A;  2E2X A;  2N0Y A;  1U5G A;  1K5D B;  1XR0 B;  2GCL A;  3ZVR A;  4HAU B;  3KRX A;  4YL8 A;  4K2P A;  4B6H A;  2COC A;  5C5B A;  2Z0P A;  5KCV A;  4F7G A;  2IYB A;  5GOW B;  2GCJ A;  1V61 A;  2MKR A;  2YVC A;  4GMX B;  1EAZ A;  1RJ2 A;  2DYN A;  1AQC A;  2DHK A;  3FM8 C;  2D9W A;  1BAK A;  5KQ4 A;  4A6H A;  3PSC A;  4GN1 A;  5KQ1 A;  3QIJ A;  4HAT B;  2CAY A;  1M7E A;  3SV1 A;  5EFX A;  2XQN M;  3PVW A;  1W1D A;  1Y19 B;  5LON B;  2DTC A;  1J0W A;  1LW3 A;  2CRF A;  2MFQ A;  4HHV A;  1X1F A;  3HQC A;  4HAX B;  2DLW A;  2CY5 A;  1N3H A;  3AU5 A;  1EGX A;  2M38 A;  2Y8G A;  5DHF B;  2COA A;  2W2X C;  2RUK B;  4DXA B;  4H8S A;  5JHG A;  4CYE A;  1XCG A;  1X11 A;  4Z2M B;  2V76 A;  2DA0 A;  1X86 A;  3TW1 A;  2X18 A;  2JP2 A;  5D27 A;  2DX1 A;  2YS3 A;  3CXB B;  1X05 A;  4C0A A;  3O96 A;  4K81 A;  4DX8 A;  1M7R A;  4A6F A;  4GMV A;  2DN6 A;  4HAZ B;  5J3Q A;  2CY4 A;  3TCA A;  2UZR A;  2HTH B;  4EMO A;  3SYX A;  3MPX A;  5JHH A;  3U8Z A;  3UZT A;  5HE1 A;  2RLO A;  1MIZ B;  1QQG A;  1V5P A;  4DBB A;  1ISN A;  2W2W A;  1WI1 A;  2DFK A;  1MAI A;  5HE2 A;  1FHX A;  4F7H A;  2UZS A;  1Y5O A;  1UPR A;  1FGY A;  3N7C A;  2IFS A;  3IVF A;  3QWM A;  2MWN B;  4KHB B;  1ZSQ A;  4CHM A;  3A98 B;  1WG7 A;  4GPT B;  3NSU A;  4HDQ A;  2LUL A;  3AJ4 A;  3ODW A;  2Y7B A;  2Z0Q A;  1DYN A;  1DRO A;  1TXD A;  1BTN A;  2ZPY A;  3PP2 A;  2ROV A;  2LG1 A;  1WJM A;  2AEH A;  1E5W A;  3DXC A;  4HDO A;  2LOZ A;  2ADZ A;  3ULC A;  1FB8 A;  3PVU A;  3BIN A;  5J3Y A;  1MPH A;  4A6K A;  1WGU A;  3GYP A;  2H7D A;  4HB2 B;  3KSY A;  5DHA B;  5CLQ B;  1FOE A;  1V5U A;  1WJ1 A;  1MIX A;  3U7D A;  1DDV A;  1BTK A;  3SO6 A;  1ZVR A;  4HAY B;  5D3Y A;  4KVG B;  3FEH A;  2YT1 A;  5CLL B;  3PVL A;  1NTY A;  2RSG A;  4EKU A;  2P0H A;  3D8F A;  3KZ1 A;  3WA0 A;  3X23 A;  2D11 A;  1H4R A;  5JLJ B;  4EJN A;  4KAX B;  5C5B B;  2P0F A;  4WVF B;  1OMW A;  3WYF B;  1MK7 B;  3CIK A;  2RNR B;  2YRY A;  2Q13 A;  2DYQ A;  4GXB A;  5C79 A;  1J19 A;  1IRS A;  3M1I B;  2D9V A;  4XWX A;  1P6S A;  2QKL A;  1Q67 A;  1DBH A;  4PNK A;  1OY2 A;  2Z0O A;  4A5K A;  3GYO A;  2YS5 A;  4YON A;  3MDB C;  2Y8F A;  1FAO A;  3F5R A;  3D8D A;  1V89 A;  1NU2 A;  3AU4 A;  3ULB A;  3VOQ A;  1ZC3 B;  1U29 A;  1EF1 A;  3ZDT A;  3KY9 A;  4CHJ A;  1UNQ A;  1XX0 A;  2YT0 A;  3FSS A;  2LOX A;  1XOD A;  4HAW B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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