1IRSA

Irs-1 ptb domain complexed with a il-4 receptor phosphopeptide, nmr, minimized average structure
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
112
structure length
112
Chain Sequence
MGPAFKEVWQVILKPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSDEFRPR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Complex (signal transduction/peptide)
source organism Homo sapiens
publication title Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain.
pubmed doi rcsb
molecule keywords IRS-1
total genus 17
structure length 112
sequence length 112
ec nomenclature
pdb deposition date 1996-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02174 IRS PTB domain (IRS-1 type)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1irsA00
4B6HA 2ELAA 2Z0QA 2NMBA 4C0AA 2R0DA 2YSZA 4TYZA 2UVMA 2ELBA 5FI1A 5HE2A 2DA0A 4HAYB 2IYBA 4TKNA 1ZSQA 5DIFB 1MK7B 2VRWB 3KRWA 4EMOA 3U8ZA 4K17A 3GYOA 1UEFA 2H7EA 2UZSA 1MKEA 5JHGA 1NTVA 2G35A 3G9WA 4WJ7A 3AU5A 3AJ4A 1QQGA 3ODWA 4ZRJA 4KAXB 1DROA 1WJMA 3ULCA 5C6RA 2R09A 1WGUA 2J0MA 5C79A 1U5FA 3A8QA 1W1HA 4KHBB 1EVHA 1H4RA 1U5EA 1RJ2A 2ROVA 2HE7A 4GMXB 3IVFA 1V5MA 4EJNA 2P0HA 1MAIA 2RLOA 1MK9B 1UPRA 2DHIA 1QC6A 3OANA 4KHAA 4ZRKA 4HAVB 4CHJA 5KCVA 5LONB 2DYNA 2P8VA 3HK0A 1X11A 1DYNA 1NI2A 4K81A 3FEHA 1EAZA 1OQNA 2MKRA 2W2XD 2I5CA 2KCJA 2D4QA 5D3XA 5FI0A 3TFMA 1EF1A 1W1GA 3ODOA 1WJ1A 1DDWA 2J0KA 3RCPA 5D3VA 2Y8FA 4F7UP 4DX8A 1SGHA 2EJ8A 1KZ7A 4Y94A 5J3TA 1NTYA 2RGNB 5HE0A 3FM8C 4DX90 1ISNA 1XR0B 3QBVB 2YS1A 2LULA 3WYFB 2YT0A 1GC6A 5L81A 2YS3A 3KY9A 2KGXB 2YF0A 1W1DA 3KZ1A 3SYXA 4F7HA 3ZVRA 3PVLA 2DFKA 4WSFA 2MFQA 1FB8A 2VSZA 2K2UA 4WVFB 3PP2A 2X18A 2D9ZA 3F0WA 1MIXA 1UNQA 1DDVA 1PFJA 5C5BB 4HAZB 2COFA 2D9YA 1DBHA 1GC7A 5JLJB 1U5GA 1NU2A 1XX0A 2UZRA 4P7IA 1J0WA 1FGYA 3HW2B 4HAUB 3PSCA 2QKMA 2RSGA 2ZPYA 2D9XA 2D11A 2K2JA 1ZC4B 2IFSA 2XQNM 1M7RA 4HDOA 1UPQA 3KSYA 1KI1B 2N23A 3N7CA 1P5TA 4GZUA 4H8SA 1MIZB 2CRFA 3FSSA 2YT1A 3PZDA 1FHWA 3UZTA 5HE1A 3BJIA 1V88A 1WG7A 3F5RA 2VKIA 5KQ1A 2M14A 3A98B 3T06A 3ML4A 3PG7A 4YL8A 3P6AA 4Z2NA 3ULBA 4GN1A 4EKUA 1AWEA 3PEGA 1SHCA 1Y5OA 2OTXA 3BINA 3CXBB 5CLLB 1X1FA 4MK0A 3HQCA 1H10A 1I7AA 2P0FA 2P0DA 3GYPA 1TQZA 2J59M 1UNRA 2QKLA 3SO6A 2L1CA 2COAA 2DYQA 4HHVA 5D3WA 4ZRIA 1U27A 1DDMA 4GMVA 2GCLA 1IRSA 2D9VA 2GJYA 5J3YA 2N0YA 2BCJA 1EGXA 4A6KA 2DTCA 4PQ0A 4GXBA 2J0JA 5KQ4A 1FOEA 2E2XA 1XKEA 1ZVRA 2MDXA 2RVBB 1KZGA 2AEHA 4A6FB 2GCJA 1Q67A 1X86A 5GOWB 2CODA 2ROZB 2COCA 2LG1A 2RNRB 3ODXA 3QIJA 4KVGB 5C5BA 1BTKA 2YRYA 4MT7A 4L6EA 2DN6A 2DX5A 3D8EA 3DXEA 1V5PA 2L2IA 5DHFB 2D9WA 2D10A 4HB3B 2OQBA 2M38A 3X23A 2LOXA 1E5WA 1OMWA 2Q13A 2LYDA 2DKQA 4D0NB 4DXAB 1MPHA 1AQCA 2EMSA 4K2PA 2RUKB 1WI1A 1LB1A 2W2WA 4PNKA 4HB2B 1J19A 2I1KA 3U7DA 4A5KA 4XWXA 1K5DB 2I5FA 3O96A 2YVCA 3A8PA 2H7DA 1U29A 3CIKA 4BBKA 2HTHB 2NZ8B 1XCGA 1PMSA 2ADZA 1M7EA 3TVVA 2YS5A 4CYEA 5D3YA 5DI9B 2CY5A 2EC1A 3AU4A 2Y8GA 5DH9B 4HAXB 2CAYA 4GPTB 3SNHA 1BAKA 3DXCA 2V76A 3QWMA 5C16A 3P7ZA 1Z87A 4HB4B 1LW3A 4IAPA 3VOQA 1WVHA 5JHHA 4DBBA 1RRPB 1TXDA 1P6SA 1X05A 2JP2A 4HDQA 4HATB 1K5GB 1V5UA 3SUZA 2Y7BA 4NY0A 4IFSA 5HE3A 2GS0A 1GG3A 1WGQA 2Z0OA 3PVWA 5LOPB 2AL6A 3MPXA 3PVUA 1ZC3B 2LKOA 3MDBC 3TO1A 4A6HA 3D8FA 3DXDA 4Z2MB 3WA0A 1UNPA 2EMTA 2W2XC 3D8DA 3TCAA 2DX1A 5EFXA 1BWNA 1XD4A 5D27A 1FHXA 1V89A 2FJLA 4KHOA 4A6FA 3V5WA 1I2HA 3M1IB 3VIAA 2DHJA 1Y19B 2K00A 2KUPA 5J3QA 5DHAB 1FGZA 5CLQB 2DHKA 2DKPA 4HAWB 2I1JA 2DLWA 1XODA 1V61A 3NSUA 1P3RA 1N3HA 4CHMA 4IOYX 3LJUX 3KRXA 4K2OA 4NSWA 4YONA 4MY6A 1OY2A 2CY4A 3SV1A 2LOZA 1U2BA 1ZM0A 2D2QA 2PZ1A 1FHOA 1BTNA 1FAOA 1TJ6A 4F7GA 5JP4A 3ZDTA 1B55A 2MWNB 2Z0PA 1PLSA 1U5DA 3TW1A 1X1GA 4HB0B
chains in the Genus database with same CATH superfamily
4B6HA 2ELAA 2Z0QA 2NMBA 4C0AA 2R0DA 2YSZA 4TYZA 2UVMA 2ELBA 5FI1A 5HE2A 2DA0A 4HAYB 2IYBA 4TKNA 1ZSQA 5DIFB 1MK7B 2VRWB 3KRWA 4EMOA 3U8ZA 4D6WA 4K17A 3GYOA 1UEFA 2H7EA 2UZSA 1MKEA 5JHGA 1NTVA 3NWDA 2G35A 3G9WA 4WJ7A 3AU5A 3AJ4A 1QQGA 3ODWA 2KIEA 4ZRJA 4KAXB 1DROA 1WJMA 3ULCA 5C6RA 2R09A 2K8EA 1WGUA 2J0MA 5C79A 1U5FA 3A8QA 1W1HA 2Z4DA 5I2SA 3OHMB 4KHBB 1EVHA 1H4RA 4OSNA 1U5EA 2GUMA 1RJ2A 2ROVA 2HE7A 3B77A 4GMXB 3IVFA 1V5MA 4EJNA 2P0HA 1MAIA 2RLOA 2Z59A 2Z14A 1MK9B 1UPRA 2DHIA 1QC6A 3OANA 4KHAA 4ZRKA 4HAVB 4CHJA 5KCVA 5LONB 2DYNA 2P8VA 3HK0A 1X11A 1DYNA 1NI2A 4K81A 3FEHA 1EAZA 1OQNA 2MKRA 2W2XD 2I5CA 2KCJA 2D4QA 5D3XA 5FI0A 3TFMA 1EF1A 1W1GA 4QXAB 3ODOA 1WJ1A 1DDWA 2J0KA 3RCPA 3NWAA 5D3VA 2Y8FA 4F7UP 4DX8A 1SGHA 2EJ8A 1KZ7A 4Y94A 5J3TA 1NTYA 2RGNB 5HE0A 3FM8C 4DX90 1ISNA 1XR0B 3QBVB 2YS1A 2LULA 3WYFB 5IRSA 2YT0A 1GC6A 1ZYIA 5L81A 2YS3A 3KY9A 2KGXB 2YF0A 1W1DA 3KZ1A 3SYXA 4F7HA 3ZVRA 3U12A 3PVLA 2DFKA 4WSFA 2MFQA 1FB8A 2VSZA 2K2UA 4WVFB 3PP2A 2X18A 2D9ZA 3F0WA 1MIXA 1UNQA 1DDVA 1PFJA 5C5BB 4HAZB 2COFA 2D9YA 1DBHA 1GC7A 5JLJB 1U5GA 3NW8A 4CSQA 1NU2A 1XX0A 2UZRA 2KIGA 4P7IA 1J0WA 1FGYA 3HW2B 4HAUB 3PSCA 2QKMA 2RSGA 2ZPYA 2D9XA 2D11A 2K2JA 1ZC4B 2IFSA 2XQNM 1M7RA 4HDOA 1UPQA 3KSYA 1KI1B 2N23A 3N7CA 1P5TA 4GZUA 4H8SA 1MIZB 2CRFA 3FSSA 2YT1A 4QJ5B 3PZDA 1FHWA 3UZTA 5HE1A 3BJIA 1V88A 4KHBA 1WG7A 3F5RA 2VKIA 5KQ1A 2M14A 3A98B 3T06A 3ML4A 3PG7A 4YL8A 3P6AA 4Z2NA 3ULBA 4GN1A 4EKUA 1AWEA 3PEGA 1SHCA 1Y5OA 2OTXA 3BINA 3CXBB 2KUQA 5CLLB 1X1FA 4MK0A 3HQCA 1H10A 1I7AA 2P0FA 2P0DA 4QJ3B 3GYPA 1TQZA 5LG4B 2J59M 1UNRA 2QKLA 3SO6A 2L1CA 2COAA 2DYQA 4HHVA 5D3WA 4ZRIA 1U27A 1DDMA 1T77A 4GMVA 2GCLA 1IRSA 2D9VA 2GJYA 5J3YA 2N0YA 2BCJA 1EGXA 4A6KA 2DTCA 4PQ0A 4GXBA 2J0JA 2ZKMX 5KQ4A 4DIXA 1FOEA 2E2XA 1XKEA 4HSIA 1ZVRA 2MDXA 2RVBB 1KZGA 2AEHA 4A6FB 4OT1A 2GCJA 1Q67A 1X86A 5GOWB 2CODA 2ROZB 2COCA 2LG1A 2RNRB 3ODXA 3QIJA 4KVGB 5C5BA 1BTKA 2YRYA 4MT7A 4L6EA 2DN6A 2DX5A 3D8EA 3DXEA 1V5PA 2L2IA 5DHFB 2D9WA 2D10A 4HB3B 2OQBA 2M38A 3X23A 4L1RA 3A58A 2LOXA 1E5WA 4QJ4B 1OMWA 2Q13A 2LYDA 2DKQA 4D0NB 4DXAB 1MPHA 1AQCA 2EMSA 4K2PA 2RUKB 2FJUB 1WI1A 1LB1A 2W2WA 4PNKA 4GOUA 4HB2B 1J19A 2I1KA 4GNKB 3U7DA 4A5KA 4XWXA 1K5DB 2I5FA 3O96A 2YVCA 3A8PA 2H7DA 1U29A 3CIKA 4BBKA 2HTHB 2NZ8B 2RRFA 1XCGA 1PMSA 2ADZA 3HIEA 1M7EA 3TVVA 2YS5A 4CYEA 3DCXA 5D3YA 5DI9B 2CY5A 2EC1A 3AU4A 2Y8GA 5DH9B 4HAXB 2CAYA 4GPTB 3SNHA 1BAKA 3DXCA 2V76A 3QWMA 5C16A 3P7ZA 1Z87A 4HB4B 1LW3A 4IAPA 3VOQA 1WVHA 5JHHA 4DBBA 1RRPB 1TXDA 1P6SA 1X05A 2JP2A 4HDQA 1MI1A 4HATB 1K5GB 3NWFA 1V5UA 3SUZA 2Y7BA 4NY0A 4IFSA 5HE3A 2GS0A 1GG3A 1WGQA 2Z0OA 3PVWA 5LOPB 2AL6A 3MPXA 3PVUA 1ZC3B 2LKOA 3MDBC 3TO1A 4A6HA 3D8FA 3DXDA 4Z2MB 3WA0A 1UNPA 2EMTA 2W2XC 3D8DA 3TCAA 2DX1A 5EFXA 1BWNA 1XD4A 5D27A 1FHXA 5I2MA 1V89A 2FJLA 4KHOA 4A6FA 3V5WA 1I2HA 3M1IB 3VIAA 3HSAA 2DHJA 1Y19B 5M4YB 2K00A 2KUPA 5J3QA 5DHAB 1FGZA 5CLQB 2DHKA 2DKPA 4HAWB 2I1JA 2DLWA 1XODA 1V61A 2NBVA 3NSUA 2K49A 1P3RA 1N3HA 4CHMA 4IOYX 3LJUX 2R2YA 3KRXA 4K2OA 4NSWA 2YT2A 4YONA 4MY6A 1OY2A 2CY4A 3SV1A 2LOZA 3FVCA 1U2BA 1ZM0A 2D2QA 2PZ1A 1FHOA 2KR0A 1BTNA 1FAOA 1TJ6A 4F7GA 5JP4A 3ZDTA 1B55A 2MWNB 2Z0PA 1PLSA 1U5DA 3TW1A 1X1GA 4HB0B 2Z13A
chains in the Genus database with same CATH topology
4B6HA 2ELAA 2Z0QA 2NMBA 4C0AA 2R0DA 2YSZA 4TYZA 2UVMA 2ELBA 5FI1A 5HE2A 2DA0A 4HAYB 2IYBA 4TKNA 1ZSQA 5DIFB 1MK7B 2VRWB 3KRWA 4EMOA 3U8ZA 4K17A 3GYOA 1UEFA 2H7EA 2UZSA 1MKEA 5JHGA 1NTVA 2G35A 3G9WA 4WJ7A 3AU5A 3AJ4A 1QQGA 3ODWA 4ZRJA 4KAXB 1DROA 1WJMA 3ULCA 5C6RA 2R09A 1WGUA 2J0MA 5C79A 1U5FA 3A8QA 1W1HA 4KHBB 1EVHA 1H4RA 1U5EA 1RJ2A 2ROVA 2HE7A 4GMXB 3IVFA 1V5MA 4EJNA 2P0HA 1MAIA 2RLOA 1MK9B 1UPRA 2DHIA 1QC6A 3OANA 4KHAA 4ZRKA 4HAVB 4CHJA 5KCVA 5LONB 2DYNA 2P8VA 3HK0A 1X11A 1DYNA 1NI2A 4K81A 3FEHA 1EAZA 1OQNA 2MKRA 2W2XD 2I5CA 2KCJA 2D4QA 5D3XA 5FI0A 3TFMA 1EF1A 1W1GA 3ODOA 1WJ1A 1DDWA 2J0KA 3RCPA 5D3VA 2Y8FA 4F7UP 4DX8A 1SGHA 2EJ8A 1KZ7A 4Y94A 5J3TA 1NTYA 2RGNB 5HE0A 3FM8C 4DX90 1ISNA 1XR0B 3QBVB 2YS1A 2LULA 3WYFB 2YT0A 1GC6A 5L81A 2YS3A 3KY9A 2KGXB 2YF0A 1W1DA 3KZ1A 3SYXA 4F7HA 3ZVRA 3PVLA 2DFKA 4WSFA 2MFQA 1FB8A 2VSZA 2K2UA 4WVFB 3PP2A 2X18A 2D9ZA 3F0WA 1MIXA 1UNQA 1DDVA 1PFJA 5C5BB 4HAZB 2COFA 2D9YA 1DBHA 1GC7A 5JLJB 1U5GA 1NU2A 1XX0A 2UZRA 4P7IA 1J0WA 1FGYA 3HW2B 4HAUB 3PSCA 2QKMA 2RSGA 2ZPYA 2D9XA 2D11A 2K2JA 1ZC4B 2IFSA 2XQNM 1M7RA 4HDOA 1UPQA 3KSYA 1KI1B 2N23A 3N7CA 1P5TA 4GZUA 4H8SA 1MIZB 2CRFA 3FSSA 2YT1A 3PZDA 1FHWA 3UZTA 5HE1A 3BJIA 1V88A 1WG7A 3F5RA 2VKIA 5KQ1A 2M14A 3A98B 3T06A 3ML4A 3PG7A 4YL8A 3P6AA 4Z2NA 3ULBA 4GN1A 4EKUA 1AWEA 3PEGA 1SHCA 1Y5OA 2OTXA 3BINA 3CXBB 5CLLB 1X1FA 4MK0A 3HQCA 1H10A 1I7AA 2P0FA 2P0DA 3GYPA 1TQZA 2J59M 1UNRA 2QKLA 3SO6A 2L1CA 2COAA 2DYQA 4HHVA 5D3WA 4ZRIA 1U27A 1DDMA 4GMVA 2GCLA 1IRSA 2D9VA 2GJYA 5J3YA 2N0YA 2BCJA 1EGXA 4A6KA 2DTCA 4PQ0A 4GXBA 2J0JA 5KQ4A 1FOEA 2E2XA 1XKEA 1ZVRA 2MDXA 2RVBB 1KZGA 2AEHA 4A6FB 2GCJA 1Q67A 1X86A 5GOWB 2CODA 2ROZB 2COCA 2LG1A 2RNRB 3ODXA 3QIJA 4KVGB 5C5BA 1BTKA 2YRYA 4MT7A 4L6EA 2DN6A 2DX5A 3D8EA 3DXEA 1V5PA 2L2IA 5DHFB 2D9WA 2D10A 4HB3B 2OQBA 2M38A 3X23A 2LOXA 1E5WA 1OMWA 2Q13A 2LYDA 2DKQA 4D0NB 4DXAB 1MPHA 1AQCA 2EMSA 4K2PA 2RUKB 1WI1A 1LB1A 2W2WA 4PNKA 4HB2B 1J19A 2I1KA 3U7DA 4A5KA 4XWXA 1K5DB 2I5FA 3O96A 2YVCA 3A8PA 2H7DA 1U29A 3CIKA 4BBKA 2HTHB 2NZ8B 1XCGA 1PMSA 2ADZA 1M7EA 3TVVA 2YS5A 4CYEA 5D3YA 5DI9B 2CY5A 2EC1A 3AU4A 2Y8GA 5DH9B 4HAXB 2CAYA 4GPTB 3SNHA 1BAKA 3DXCA 2V76A 3QWMA 5C16A 3P7ZA 1Z87A 4HB4B 1LW3A 4IAPA 3VOQA 1WVHA 5JHHA 4DBBA 1RRPB 1TXDA 1P6SA 1X05A 2JP2A 4HDQA 4HATB 1K5GB 1V5UA 3SUZA 2Y7BA 4NY0A 4IFSA 5HE3A 2GS0A 1GG3A 1WGQA 2Z0OA 3PVWA 5LOPB 2AL6A 3MPXA 3PVUA 1ZC3B 2LKOA 3MDBC 3TO1A 4A6HA 3D8FA 3DXDA 4Z2MB 3WA0A 1UNPA 2EMTA 2W2XC 3D8DA 3TCAA 2DX1A 5EFXA 1BWNA 1XD4A 5D27A 1FHXA 1V89A 2FJLA 4KHOA 4A6FA 3V5WA 1I2HA 3M1IB 3VIAA 2DHJA 1Y19B 2K00A 2KUPA 5J3QA 5DHAB 1FGZA 5CLQB 2DHKA 2DKPA 4HAWB 2I1JA 2DLWA 1XODA 1V61A 3NSUA 1P3RA 1N3HA 4CHMA 4IOYX 3LJUX 3KRXA 4K2OA 4NSWA 4YONA 4MY6A 1OY2A 2CY4A 3SV1A 2LOZA 1U2BA 1ZM0A 2D2QA 2PZ1A 1FHOA 1BTNA 1FAOA 1TJ6A 4F7GA 5JP4A 3ZDTA 1B55A 2MWNB 2Z0PA 1PLSA 1U5DA 3TW1A 1X1GA 4HB0B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4B6H A;  2ELA A;  2Z0Q A;  2NMB A;  4C0A A;  2R0D A;  2YSZ A;  4TYZ A;  2UVM A;  2ELB A;  5FI1 A;  5HE2 A;  2DA0 A;  4HAY B;  2IYB A;  4TKN A;  1ZSQ A;  5DIF B;  1MK7 B;  2VRW B;  3KRW A;  4EMO A;  3U8Z A;  4K17 A;  3GYO A;  1UEF A;  2H7E A;  2UZS A;  1MKE A;  5JHG A;  1NTV A;  2G35 A;  3G9W A;  4WJ7 A;  3AU5 A;  3AJ4 A;  1QQG A;  3ODW A;  4ZRJ A;  4KAX B;  1DRO A;  1WJM A;  3ULC A;  5C6R A;  2R09 A;  1WGU A;  2J0M A;  5C79 A;  1U5F A;  3A8Q A;  1W1H A;  4KHB B;  1EVH A;  1H4R A;  1U5E A;  1RJ2 A;  2ROV A;  2HE7 A;  4GMX B;  3IVF A;  1V5M A;  4EJN A;  2P0H A;  1MAI A;  2RLO A;  1MK9 B;  1UPR A;  2DHI A;  1QC6 A;  3OAN A;  4KHA A;  4ZRK A;  4HAV B;  4CHJ A;  5KCV A;  5LON B;  2DYN A;  2P8V A;  3HK0 A;  1X11 A;  1DYN A;  1NI2 A;  4K81 A;  3FEH A;  1EAZ A;  1OQN A;  2MKR A;  2W2X D;  2I5C A;  2KCJ A;  2D4Q A;  5D3X A;  5FI0 A;  3TFM A;  1EF1 A;  1W1G A;  3ODO A;  1WJ1 A;  1DDW A;  2J0K A;  3RCP A;  5D3V A;  2Y8F A;  4F7U P;  4DX8 A;  1SGH A;  2EJ8 A;  1KZ7 A;  4Y94 A;  5J3T A;  1NTY A;  2RGN B;  5HE0 A;  3FM8 C;  4DX9 0;  1ISN A;  1XR0 B;  3QBV B;  2YS1 A;  2LUL A;  3WYF B;  2YT0 A;  1GC6 A;  5L81 A;  2YS3 A;  3KY9 A;  2KGX B;  2YF0 A;  1W1D A;  3KZ1 A;  3SYX A;  4F7H A;  3ZVR A;  3PVL A;  2DFK A;  4WSF A;  2MFQ A;  1FB8 A;  2VSZ A;  2K2U A;  4WVF B;  3PP2 A;  2X18 A;  2D9Z A;  3F0W A;  1MIX A;  1UNQ A;  1DDV A;  1PFJ A;  5C5B B;  4HAZ B;  2COF A;  2D9Y A;  1DBH A;  1GC7 A;  5JLJ B;  1U5G A;  1NU2 A;  1XX0 A;  2UZR A;  4P7I A;  1J0W A;  1FGY A;  3HW2 B;  4HAU B;  3PSC A;  2QKM A;  2RSG A;  2ZPY A;  2D9X A;  2D11 A;  2K2J A;  1ZC4 B;  2IFS A;  2XQN M;  1M7R A;  4HDO A;  1UPQ A;  3KSY A;  1KI1 B;  2N23 A;  3N7C A;  1P5T A;  4GZU A;  4H8S A;  1MIZ B;  2CRF A;  3FSS A;  2YT1 A;  3PZD A;  1FHW A;  3UZT A;  5HE1 A;  3BJI A;  1V88 A;  1WG7 A;  3F5R A;  2VKI A;  5KQ1 A;  2M14 A;  3A98 B;  3T06 A;  3ML4 A;  3PG7 A;  4YL8 A;  3P6A A;  4Z2N A;  3ULB A;  4GN1 A;  4EKU A;  1AWE A;  3PEG A;  1SHC A;  1Y5O A;  2OTX A;  3BIN A;  3CXB B;  5CLL B;  1X1F A;  4MK0 A;  3HQC A;  1H10 A;  1I7A A;  2P0F A;  2P0D A;  3GYP A;  1TQZ A;  2J59 M;  1UNR A;  2QKL A;  3SO6 A;  2L1C A;  2COA A;  2DYQ A;  4HHV A;  5D3W A;  4ZRI A;  1U27 A;  1DDM A;  4GMV A;  2GCL A;  1IRS A;  2D9V A;  2GJY A;  5J3Y A;  2N0Y A;  2BCJ A;  1EGX A;  4A6K A;  2DTC A;  4PQ0 A;  4GXB A;  2J0J A;  5KQ4 A;  1FOE A;  2E2X A;  1XKE A;  1ZVR A;  2MDX A;  2RVB B;  1KZG A;  2AEH A;  4A6F B;  2GCJ A;  1Q67 A;  1X86 A;  5GOW B;  2COD A;  2ROZ B;  2COC A;  2LG1 A;  2RNR B;  3ODX A;  3QIJ A;  4KVG B;  5C5B A;  1BTK A;  2YRY A;  4MT7 A;  4L6E A;  2DN6 A;  2DX5 A;  3D8E A;  3DXE A;  1V5P A;  2L2I A;  5DHF B;  2D9W A;  2D10 A;  4HB3 B;  2OQB A;  2M38 A;  3X23 A;  2LOX A;  1E5W A;  1OMW A;  2Q13 A;  2LYD A;  2DKQ A;  4D0N B;  4DXA B;  1MPH A;  1AQC A;  2EMS A;  4K2P A;  2RUK B;  1WI1 A;  1LB1 A;  2W2W A;  4PNK A;  4HB2 B;  1J19 A;  2I1K A;  3U7D A;  4A5K A;  4XWX A;  1K5D B;  2I5F A;  3O96 A;  2YVC A;  3A8P A;  2H7D A;  1U29 A;  3CIK A;  4BBK A;  2HTH B;  2NZ8 B;  1XCG A;  1PMS A;  2ADZ A;  1M7E A;  3TVV A;  2YS5 A;  4CYE A;  5D3Y A;  5DI9 B;  2CY5 A;  2EC1 A;  3AU4 A;  2Y8G A;  5DH9 B;  4HAX B;  2CAY A;  4GPT B;  3SNH A;  1BAK A;  3DXC A;  2V76 A;  3QWM A;  5C16 A;  3P7Z A;  1Z87 A;  4HB4 B;  1LW3 A;  4IAP A;  3VOQ A;  1WVH A;  5JHH A;  4DBB A;  1RRP B;  1TXD A;  1P6S A;  1X05 A;  2JP2 A;  4HDQ A;  4HAT B;  1K5G B;  1V5U A;  3SUZ A;  2Y7B A;  4NY0 A;  4IFS A;  5HE3 A;  2GS0 A;  1GG3 A;  1WGQ A;  2Z0O A;  3PVW A;  5LOP B;  2AL6 A;  3MPX A;  3PVU A;  1ZC3 B;  2LKO A;  3MDB C;  3TO1 A;  4A6H A;  3D8F A;  3DXD A;  4Z2M B;  3WA0 A;  1UNP A;  2EMT A;  2W2X C;  3D8D A;  3TCA A;  2DX1 A;  5EFX A;  1BWN A;  1XD4 A;  5D27 A;  1FHX A;  1V89 A;  2FJL A;  4KHO A;  4A6F A;  3V5W A;  1I2H A;  3M1I B;  3VIA A;  2DHJ A;  1Y19 B;  2K00 A;  2KUP A;  5J3Q A;  5DHA B;  1FGZ A;  5CLQ B;  2DHK A;  2DKP A;  4HAW B;  2I1J A;  2DLW A;  1XOD A;  1V61 A;  3NSU A;  1P3R A;  1N3H A;  4CHM A;  4IOY X;  3LJU X;  3KRX A;  4K2O A;  4NSW A;  4YON A;  4MY6 A;  1OY2 A;  2CY4 A;  3SV1 A;  2LOZ A;  1U2B A;  1ZM0 A;  2D2Q A;  2PZ1 A;  1FHO A;  1BTN A;  1FAO A;  1TJ6 A;  4F7G A;  5JP4 A;  3ZDT A;  1B55 A;  2MWN B;  2Z0P A;  1PLS A;  1U5D A;  3TW1 A;  1X1G A;  4HB0 B; 
#chains in the Genus database with same CATH topology
 4B6H A;  2ELA A;  2Z0Q A;  2NMB A;  4C0A A;  2R0D A;  2YSZ A;  4TYZ A;  2UVM A;  2ELB A;  5FI1 A;  5HE2 A;  2DA0 A;  4HAY B;  2IYB A;  4TKN A;  1ZSQ A;  5DIF B;  1MK7 B;  2VRW B;  3KRW A;  4EMO A;  3U8Z A;  4D6W A;  4K17 A;  3GYO A;  1UEF A;  2H7E A;  2UZS A;  1MKE A;  5JHG A;  1NTV A;  3NWD A;  2G35 A;  3G9W A;  4WJ7 A;  3AU5 A;  3AJ4 A;  1QQG A;  3ODW A;  2KIE A;  4ZRJ A;  4KAX B;  1DRO A;  1WJM A;  3ULC A;  5C6R A;  2R09 A;  2K8E A;  1WGU A;  2J0M A;  5C79 A;  1U5F A;  3A8Q A;  1W1H A;  2Z4D A;  5I2S A;  3OHM B;  4KHB B;  1EVH A;  1H4R A;  4OSN A;  1U5E A;  2GUM A;  1RJ2 A;  2ROV A;  2HE7 A;  3B77 A;  4GMX B;  3IVF A;  1V5M A;  4EJN A;  2P0H A;  1MAI A;  2RLO A;  2Z59 A;  2Z14 A;  1MK9 B;  1UPR A;  2DHI A;  1QC6 A;  3OAN A;  4KHA A;  4ZRK A;  4HAV B;  4CHJ A;  5KCV A;  5LON B;  2DYN A;  2P8V A;  3HK0 A;  1X11 A;  1DYN A;  1NI2 A;  4K81 A;  3FEH A;  1EAZ A;  1OQN A;  2MKR A;  2W2X D;  2I5C A;  2KCJ A;  2D4Q A;  5D3X A;  5FI0 A;  3TFM A;  1EF1 A;  1W1G A;  4QXA B;  3ODO A;  1WJ1 A;  1DDW A;  2J0K A;  3RCP A;  3NWA A;  5D3V A;  2Y8F A;  4F7U P;  4DX8 A;  1SGH A;  2EJ8 A;  1KZ7 A;  4Y94 A;  5J3T A;  1NTY A;  2RGN B;  5HE0 A;  3FM8 C;  4DX9 0;  1ISN A;  1XR0 B;  3QBV B;  2YS1 A;  2LUL A;  3WYF B;  5IRS A;  2YT0 A;  1GC6 A;  1ZYI A;  5L81 A;  2YS3 A;  3KY9 A;  2KGX B;  2YF0 A;  1W1D A;  3KZ1 A;  3SYX A;  4F7H A;  3ZVR A;  3U12 A;  3PVL A;  2DFK A;  4WSF A;  2MFQ A;  1FB8 A;  2VSZ A;  2K2U A;  4WVF B;  3PP2 A;  2X18 A;  2D9Z A;  3F0W A;  1MIX A;  1UNQ A;  1DDV A;  1PFJ A;  5C5B B;  4HAZ B;  2COF A;  2D9Y A;  1DBH A;  1GC7 A;  5JLJ B;  1U5G A;  3NW8 A;  4CSQ A;  1NU2 A;  1XX0 A;  2UZR A;  2KIG A;  4P7I A;  1J0W A;  1FGY A;  3HW2 B;  4HAU B;  3PSC A;  2QKM A;  2RSG A;  2ZPY A;  2D9X A;  2D11 A;  2K2J A;  1ZC4 B;  2IFS A;  2XQN M;  1M7R A;  4HDO A;  1UPQ A;  3KSY A;  1KI1 B;  2N23 A;  3N7C A;  1P5T A;  4GZU A;  4H8S A;  1MIZ B;  2CRF A;  3FSS A;  2YT1 A;  4QJ5 B;  3PZD A;  1FHW A;  3UZT A;  5HE1 A;  3BJI A;  1V88 A;  4KHB A;  1WG7 A;  3F5R A;  2VKI A;  5KQ1 A;  2M14 A;  3A98 B;  3T06 A;  3ML4 A;  3PG7 A;  4YL8 A;  3P6A A;  4Z2N A;  3ULB A;  4GN1 A;  4EKU A;  1AWE A;  3PEG A;  1SHC A;  1Y5O A;  2OTX A;  3BIN A;  3CXB B;  2KUQ A;  5CLL B;  1X1F A;  4MK0 A;  3HQC A;  1H10 A;  1I7A A;  2P0F A;  2P0D A;  4QJ3 B;  3GYP A;  1TQZ A;  5LG4 B;  2J59 M;  1UNR A;  2QKL A;  3SO6 A;  2L1C A;  2COA A;  2DYQ A;  4HHV A;  5D3W A;  4ZRI A;  1U27 A;  1DDM A;  1T77 A;  4GMV A;  2GCL A;  1IRS A;  2D9V A;  2GJY A;  5J3Y A;  2N0Y A;  2BCJ A;  1EGX A;  4A6K A;  2DTC A;  4PQ0 A;  4GXB A;  2J0J A;  2ZKM X;  5KQ4 A;  4DIX A;  1FOE A;  2E2X A;  1XKE A;  4HSI A;  1ZVR A;  2MDX A;  2RVB B;  1KZG A;  2AEH A;  4A6F B;  4OT1 A;  2GCJ A;  1Q67 A;  1X86 A;  5GOW B;  2COD A;  2ROZ B;  2COC A;  2LG1 A;  2RNR B;  3ODX A;  3QIJ A;  4KVG B;  5C5B A;  1BTK A;  2YRY A;  4MT7 A;  4L6E A;  2DN6 A;  2DX5 A;  3D8E A;  3DXE A;  1V5P A;  2L2I A;  5DHF B;  2D9W A;  2D10 A;  4HB3 B;  2OQB A;  2M38 A;  3X23 A;  4L1R A;  3A58 A;  2LOX A;  1E5W A;  4QJ4 B;  1OMW A;  2Q13 A;  2LYD A;  2DKQ A;  4D0N B;  4DXA B;  1MPH A;  1AQC A;  2EMS A;  4K2P A;  2RUK B;  2FJU B;  1WI1 A;  1LB1 A;  2W2W A;  4PNK A;  4GOU A;  4HB2 B;  1J19 A;  2I1K A;  4GNK B;  3U7D A;  4A5K A;  4XWX A;  1K5D B;  2I5F A;  3O96 A;  2YVC A;  3A8P A;  2H7D A;  1U29 A;  3CIK A;  4BBK A;  2HTH B;  2NZ8 B;  2RRF A;  1XCG A;  1PMS A;  2ADZ A;  3HIE A;  1M7E A;  3TVV A;  2YS5 A;  4CYE A;  3DCX A;  5D3Y A;  5DI9 B;  2CY5 A;  2EC1 A;  3AU4 A;  2Y8G A;  5DH9 B;  4HAX B;  2CAY A;  4GPT B;  3SNH A;  1BAK A;  3DXC A;  2V76 A;  3QWM A;  5C16 A;  3P7Z A;  1Z87 A;  4HB4 B;  1LW3 A;  4IAP A;  3VOQ A;  1WVH A;  5JHH A;  4DBB A;  1RRP B;  1TXD A;  1P6S A;  1X05 A;  2JP2 A;  4HDQ A;  1MI1 A;  4HAT B;  1K5G B;  3NWF A;  1V5U A;  3SUZ A;  2Y7B A;  4NY0 A;  4IFS A;  5HE3 A;  2GS0 A;  1GG3 A;  1WGQ A;  2Z0O A;  3PVW A;  5LOP B;  2AL6 A;  3MPX A;  3PVU A;  1ZC3 B;  2LKO A;  3MDB C;  3TO1 A;  4A6H A;  3D8F A;  3DXD A;  4Z2M B;  3WA0 A;  1UNP A;  2EMT A;  2W2X C;  3D8D A;  3TCA A;  2DX1 A;  5EFX A;  1BWN A;  1XD4 A;  5D27 A;  1FHX A;  5I2M A;  1V89 A;  2FJL A;  4KHO A;  4A6F A;  3V5W A;  1I2H A;  3M1I B;  3VIA A;  3HSA A;  2DHJ A;  1Y19 B;  5M4Y B;  2K00 A;  2KUP A;  5J3Q A;  5DHA B;  1FGZ A;  5CLQ B;  2DHK A;  2DKP A;  4HAW B;  2I1J A;  2DLW A;  1XOD A;  1V61 A;  2NBV A;  3NSU A;  2K49 A;  1P3R A;  1N3H A;  4CHM A;  4IOY X;  3LJU X;  2R2Y A;  3KRX A;  4K2O A;  4NSW A;  2YT2 A;  4YON A;  4MY6 A;  1OY2 A;  2CY4 A;  3SV1 A;  2LOZ A;  3FVC A;  1U2B A;  1ZM0 A;  2D2Q A;  2PZ1 A;  1FHO A;  2KR0 A;  1BTN A;  1FAO A;  1TJ6 A;  4F7G A;  5JP4 A;  3ZDT A;  1B55 A;  2MWN B;  2Z0P A;  1PLS A;  1U5D A;  3TW1 A;  1X1G A;  4HB0 B;  2Z13 A; 
#chains in the Genus database with same CATH homology
 4B6H A;  2ELA A;  2Z0Q A;  2NMB A;  4C0A A;  2R0D A;  2YSZ A;  4TYZ A;  2UVM A;  2ELB A;  5FI1 A;  5HE2 A;  2DA0 A;  4HAY B;  2IYB A;  4TKN A;  1ZSQ A;  5DIF B;  1MK7 B;  2VRW B;  3KRW A;  4EMO A;  3U8Z A;  4K17 A;  3GYO A;  1UEF A;  2H7E A;  2UZS A;  1MKE A;  5JHG A;  1NTV A;  2G35 A;  3G9W A;  4WJ7 A;  3AU5 A;  3AJ4 A;  1QQG A;  3ODW A;  4ZRJ A;  4KAX B;  1DRO A;  1WJM A;  3ULC A;  5C6R A;  2R09 A;  1WGU A;  2J0M A;  5C79 A;  1U5F A;  3A8Q A;  1W1H A;  4KHB B;  1EVH A;  1H4R A;  1U5E A;  1RJ2 A;  2ROV A;  2HE7 A;  4GMX B;  3IVF A;  1V5M A;  4EJN A;  2P0H A;  1MAI A;  2RLO A;  1MK9 B;  1UPR A;  2DHI A;  1QC6 A;  3OAN A;  4KHA A;  4ZRK A;  4HAV B;  4CHJ A;  5KCV A;  5LON B;  2DYN A;  2P8V A;  3HK0 A;  1X11 A;  1DYN A;  1NI2 A;  4K81 A;  3FEH A;  1EAZ A;  1OQN A;  2MKR A;  2W2X D;  2I5C A;  2KCJ A;  2D4Q A;  5D3X A;  5FI0 A;  3TFM A;  1EF1 A;  1W1G A;  3ODO A;  1WJ1 A;  1DDW A;  2J0K A;  3RCP A;  5D3V A;  2Y8F A;  4F7U P;  4DX8 A;  1SGH A;  2EJ8 A;  1KZ7 A;  4Y94 A;  5J3T A;  1NTY A;  2RGN B;  5HE0 A;  3FM8 C;  4DX9 0;  1ISN A;  1XR0 B;  3QBV B;  2YS1 A;  2LUL A;  3WYF B;  2YT0 A;  1GC6 A;  5L81 A;  2YS3 A;  3KY9 A;  2KGX B;  2YF0 A;  1W1D A;  3KZ1 A;  3SYX A;  4F7H A;  3ZVR A;  3PVL A;  2DFK A;  4WSF A;  2MFQ A;  1FB8 A;  2VSZ A;  2K2U A;  4WVF B;  3PP2 A;  2X18 A;  2D9Z A;  3F0W A;  1MIX A;  1UNQ A;  1DDV A;  1PFJ A;  5C5B B;  4HAZ B;  2COF A;  2D9Y A;  1DBH A;  1GC7 A;  5JLJ B;  1U5G A;  1NU2 A;  1XX0 A;  2UZR A;  4P7I A;  1J0W A;  1FGY A;  3HW2 B;  4HAU B;  3PSC A;  2QKM A;  2RSG A;  2ZPY A;  2D9X A;  2D11 A;  2K2J A;  1ZC4 B;  2IFS A;  2XQN M;  1M7R A;  4HDO A;  1UPQ A;  3KSY A;  1KI1 B;  2N23 A;  3N7C A;  1P5T A;  4GZU A;  4H8S A;  1MIZ B;  2CRF A;  3FSS A;  2YT1 A;  3PZD A;  1FHW A;  3UZT A;  5HE1 A;  3BJI A;  1V88 A;  1WG7 A;  3F5R A;  2VKI A;  5KQ1 A;  2M14 A;  3A98 B;  3T06 A;  3ML4 A;  3PG7 A;  4YL8 A;  3P6A A;  4Z2N A;  3ULB A;  4GN1 A;  4EKU A;  1AWE A;  3PEG A;  1SHC A;  1Y5O A;  2OTX A;  3BIN A;  3CXB B;  5CLL B;  1X1F A;  4MK0 A;  3HQC A;  1H10 A;  1I7A A;  2P0F A;  2P0D A;  3GYP A;  1TQZ A;  2J59 M;  1UNR A;  2QKL A;  3SO6 A;  2L1C A;  2COA A;  2DYQ A;  4HHV A;  5D3W A;  4ZRI A;  1U27 A;  1DDM A;  4GMV A;  2GCL A;  1IRS A;  2D9V A;  2GJY A;  5J3Y A;  2N0Y A;  2BCJ A;  1EGX A;  4A6K A;  2DTC A;  4PQ0 A;  4GXB A;  2J0J A;  5KQ4 A;  1FOE A;  2E2X A;  1XKE A;  1ZVR A;  2MDX A;  2RVB B;  1KZG A;  2AEH A;  4A6F B;  2GCJ A;  1Q67 A;  1X86 A;  5GOW B;  2COD A;  2ROZ B;  2COC A;  2LG1 A;  2RNR B;  3ODX A;  3QIJ A;  4KVG B;  5C5B A;  1BTK A;  2YRY A;  4MT7 A;  4L6E A;  2DN6 A;  2DX5 A;  3D8E A;  3DXE A;  1V5P A;  2L2I A;  5DHF B;  2D9W A;  2D10 A;  4HB3 B;  2OQB A;  2M38 A;  3X23 A;  2LOX A;  1E5W A;  1OMW A;  2Q13 A;  2LYD A;  2DKQ A;  4D0N B;  4DXA B;  1MPH A;  1AQC A;  2EMS A;  4K2P A;  2RUK B;  1WI1 A;  1LB1 A;  2W2W A;  4PNK A;  4HB2 B;  1J19 A;  2I1K A;  3U7D A;  4A5K A;  4XWX A;  1K5D B;  2I5F A;  3O96 A;  2YVC A;  3A8P A;  2H7D A;  1U29 A;  3CIK A;  4BBK A;  2HTH B;  2NZ8 B;  1XCG A;  1PMS A;  2ADZ A;  1M7E A;  3TVV A;  2YS5 A;  4CYE A;  5D3Y A;  5DI9 B;  2CY5 A;  2EC1 A;  3AU4 A;  2Y8G A;  5DH9 B;  4HAX B;  2CAY A;  4GPT B;  3SNH A;  1BAK A;  3DXC A;  2V76 A;  3QWM A;  5C16 A;  3P7Z A;  1Z87 A;  4HB4 B;  1LW3 A;  4IAP A;  3VOQ A;  1WVH A;  5JHH A;  4DBB A;  1RRP B;  1TXD A;  1P6S A;  1X05 A;  2JP2 A;  4HDQ A;  4HAT B;  1K5G B;  1V5U A;  3SUZ A;  2Y7B A;  4NY0 A;  4IFS A;  5HE3 A;  2GS0 A;  1GG3 A;  1WGQ A;  2Z0O A;  3PVW A;  5LOP B;  2AL6 A;  3MPX A;  3PVU A;  1ZC3 B;  2LKO A;  3MDB C;  3TO1 A;  4A6H A;  3D8F A;  3DXD A;  4Z2M B;  3WA0 A;  1UNP A;  2EMT A;  2W2X C;  3D8D A;  3TCA A;  2DX1 A;  5EFX A;  1BWN A;  1XD4 A;  5D27 A;  1FHX A;  1V89 A;  2FJL A;  4KHO A;  4A6F A;  3V5W A;  1I2H A;  3M1I B;  3VIA A;  2DHJ A;  1Y19 B;  2K00 A;  2KUP A;  5J3Q A;  5DHA B;  1FGZ A;  5CLQ B;  2DHK A;  2DKP A;  4HAW B;  2I1J A;  2DLW A;  1XOD A;  1V61 A;  3NSU A;  1P3R A;  1N3H A;  4CHM A;  4IOY X;  3LJU X;  3KRX A;  4K2O A;  4NSW A;  4YON A;  4MY6 A;  1OY2 A;  2CY4 A;  3SV1 A;  2LOZ A;  1U2B A;  1ZM0 A;  2D2Q A;  2PZ1 A;  1FHO A;  1BTN A;  1FAO A;  1TJ6 A;  4F7G A;  5JP4 A;  3ZDT A;  1B55 A;  2MWN B;  2Z0P A;  1PLS A;  1U5D A;  3TW1 A;  1X1G A;  4HB0 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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