1M7R | Genus

Total Genus 177

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	177
sequence length	513
structure length	513
Chain Sequence	EEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHSSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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Time for openFile(/file/5cfb93be94e8e74666e62f5c/pdb.gz): 2086 ms

reading 513 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

513 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 88 ms

Adding embedded #jmolscript: select ({0:512});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Hydrolase
source organism	Homo sapiens
publication title	Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndrome pubmed doi rcsb
molecule keywords	Myotubularin-related Protein-2
total genus	177
structure length	513
sequence length	513
chains with identical sequence	B
ec nomenclature	ec 3.1.3.64: Phosphatidylinositol-3-phosphatase.
pdb deposition date	2002-07-22

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02893	GRAM	GRAM domain
A	PF06602	Myotub-related	Myotubularin-like phosphatase domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.30.29.30	Mainly Beta	Roll	PH-domain like	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	1m7rA01

4BBKA 4CHJA 2RSGA 4YL8A 1MK7B 5JLJB 5LONB 1KZ7A 2K2UA 3FEHA 3ZVRA 3V5WA 3DXEA 1U5FA 1NI2A 3KRXA 1NU2A 4IAPA 2M14A 1MK9B 2DLWA 2RVBB 4MY6A 2W2XD 1U27A 1X1GA 3N7CA 2K2JA 1UNQA 3VIAA 1V88A 2YT0A 2DN6A 3F0WA 2EMSA 3GYPA 3VOQA 4HB2B 1U5EA 3BJIA 2AL6A 4KHBB 2AEHA 4ZRJA 3DXDA 1BWNA 1GC7A 4Y94A 1I7AA 2R09A 2P0DA 1V89A 2GCLA 3AJ4A 5JP4A 1B55A 3WYFB 5C6RA 2Y8FA 1IRSA 4HB0B 4HAWB 3PZDA 3TVVA 1SHCA 5LOPB 1KZGA 2DKPA 1X1FA 1ZC4B 1UPQA 1RJ2A 1FAOA 2CODA 4B6HA 4KHOA 2HTHB 1UNRA 1PFJA 2YF0A 2YS1A 2D2QA 4A6FA 4F7UP 3P6AA 2Z0OA 2YT1A 3QBVB 4XWXA 3ML4A 2YVCA 2VRWB 1ZSQA 4P7IA 4WSFA 2D9YA 2DYNA 3KRWA 1DBHA 4Z2MB 3TW1A 1FOEA 2Y7BA 1DDWA 1LW3A 1Y19B 2P0FA 3PEGA 4K2OA 3SYXA 2GS0A 2DKQA 2EMTA 2I5CA 2RNRB 1NTYA 1U5GA 5DHFB 5J3YA 5J3QA 3FSSA 1WI1A 4GMXB 2Z0PA 5HE1A 5J3TA 5KCVA 1P5TA 2OQBA 3P7ZA 1P6SA 4KVGB 2Q13A 4ZRIA 1X11A 2GJYA 3PVWA 1V61A 4ZRKA 3U8ZA 1Y5OA 1BAKA 1Q67A 2KGXB 2PZ1A 4HAUB 2LULA 3HQCA 1FHXA 3ODXA 4C0AA 4CYEA 3SUZA 1DDVA 3BINA 2DFKA 1GC6A 1MAIA 1V5UA 5L81A 3D8DA 4KHAA 3D8FA 2IYBA 1U29A 4GN1A 2XQNM 2H7DA 2J0KA 3HK0A 4A6HA 5D3XA 1MIXA 4HB4B 2UZSA 4K17A 3MPXA 5JHHA 2I5FA 3X23A 4A6FB 4HAXB 2N0YA 2DX1A 3PG7A 4HDOA 3A8QA 2ELBA 2MDXA 1FB8A 1UEFA 4DX8A 2X18A 1H4RA 1Z87A 3OANA 4HHVA 2J0JA 2CY5A 3AU5A 1EAZA 3IVFA 2MKRA 3RCPA 5JHGA 1EGXA 2RUKB 5CLQB 1SGHA 2J59M 1X86A 5C5BA 2COFA 2D9WA 3A8PA 2LOXA 3PVUA 1MKEA 1N3HA 1MPHA 2J0MA 1XD4A 3ULCA 2OTXA 2DYQA 1TJ6A 2P0HA 1ZC3B 1ZM0A 5CLLB 3CIKA 2KCJA 5D3VA 1WGQA 3QIJA 4DBBA 1XR0B 1EVHA 3QWMA 2W2XC 1OY2A 2CRFA 3PP2A 2H7EA 4WJ7A 2JP2A 5DI9B 1TQZA 2NMBA 4NY0A 2G35A 2CY4A 1WVHA 4YONA 1NTVA 3GYOA 2YSZA 5FI0A 2YRYA 1FHWA 2ROZB 1TXDA 2UVMA 1FGYA 2D9VA 4GMVA 4H8SA 1MIZB 1QQGA 3TO1A 4KAXB 1WJ1A 1W1DA 1ISNA 5DHAB 3TCAA 5KQ4A 1DYNA 2D9XA 1W1GA 2V76A 3MDBC 4K2PA 1AWEA 1M7EA 4MT7A 4A6KA 4D0NB 4TYZA 1AQCA 4GXBA 1UPRA 2W2WA 1OMWA 4HATB 4EMOA 2YS5A 1DROA 1XODA 2P8VA 2IFSA 5C5BB 2DHJA 2KUPA 2EC1A 2I1KA 2Y8GA 1PLSA 1LB1A 4DX90 2D9ZA 2QKLA 1J19A 4MK0A 2DHKA 3DXCA 1RRPB 2LG1A 2QKMA 5HE0A 1P3RA 2UZRA 4HAVB 4L6EA 3WA0A 1U5DA 2BCJA 4Z2NA 2VKIA 3G9WA 2L2IA 1KI1B 1XX0A 5KQ1A 3PSCA 3SO6A 3U7DA 2NZ8B 4GPTB 1DDMA 1X05A 3ODWA 1U2BA 3PVLA 4PQ0A 2GCJA 1K5DB 1M7RA 2DA0A 1XCGA 4CHMA 4F7HA 1OQNA 1V5MA 2DHIA 2D10A 5D3WA 4GZUA 3AU4A 2ROVA 3KSYA 5C16A 4HAYB 2ADZA 5DIFB 3UZTA 2DTCA 2LYDA 2ZPYA 3F5RA 5DH9B 5D3YA 1UNPA 2FJLA 3ZDTA 1W1HA 3T06A 4F7GA 3ODOA 2E2XA 3A98B 3ULBA 1V5PA 2EJ8A 3M1IB 4NSWA 3CXBB 4HAZB 1H10A 4WVFB 1BTKA 1K5GB 1I2HA 1WGUA 2RLOA 4IFSA 4EJNA 1FGZA 5HE3A 2HE7A 5C79A 1FHOA 2VSZA 3FM8C 2MFQA 3D8EA 3SV1A 2Z0QA 3TFMA 4K81A 2DX5A 2D4QA 4HB3B 2N23A 4PNKA 3LJUX 1BTNA 5EFXA 2K00A 5HE2A 1PMSA 1EF1A 2CAYA 2LKOA 3HW2B 4HDQA 2RGNB 5D27A 3O96A 2L1CA 2COAA 4A5KA 2M38A 1E5WA 4DXAB 5FI1A 4EKUA 2YS3A 2ELAA 3SNHA 4TKNA 1WJMA 2I1JA 2MWNB 2COCA 2D11A 4IOYX 2R0DA 1J0WA 1GG3A 3NSUA 5GOWB 1XKEA 3KZ1A 3KY9A 2LOZA 1WG7A 1ZVRA 1QC6A
chains in the Genus database with same CATH superfamily

4BBKA 4CHJA 2RSGA 4YL8A 1MK7B 5JLJB 5LONB 1KZ7A 2FJUB 2K2UA 3FEHA 3ZVRA 3V5WA 3DXEA 1U5FA 1NI2A 3KRXA 1NU2A 4IAPA 2KR0A 2M14A 1MK9B 2DLWA 2RVBB 4MY6A 2W2XD 1U27A 1X1GA 3N7CA 2K2JA 1UNQA 3VIAA 1V88A 3U12A 2YT0A 2DN6A 3F0WA 2EMSA 3GYPA 3VOQA 4HB2B 1U5EA 3BJIA 2AL6A 4KHBB 2AEHA 4ZRJA 3HSAA 3NWAA 3DXDA 1BWNA 1GC7A 4Y94A 1I7AA 2R09A 2P0DA 1V89A 2GCLA 2Z14A 3AJ4A 5JP4A 1B55A 3WYFB 5C6RA 2Y8FA 1IRSA 4HB0B 4HAWB 3PZDA 3DCXA 3TVVA 1SHCA 5LOPB 1KZGA 2DKPA 1X1FA 1ZC4B 1UPQA 1RJ2A 1FAOA 2CODA 4B6HA 4KHOA 2HTHB 1UNRA 1PFJA 2YF0A 2YS1A 1T77A 2D2QA 4A6FA 4F7UP 3P6AA 2Z0OA 2YT1A 3QBVB 4XWXA 3ML4A 2YVCA 2VRWB 1ZSQA 4P7IA 4WSFA 2D9YA 2DYNA 3KRWA 1DBHA 4Z2MB 2Z13A 3TW1A 1FOEA 5M4YB 2Y7BA 4D6WA 1DDWA 1LW3A 1Y19B 2P0FA 3PEGA 4K2OA 3SYXA 2K8EA 2GS0A 2DKQA 2EMTA 2I5CA 2RNRB 1NTYA 1U5GA 5DHFB 5J3YA 5J3QA 3FSSA 1WI1A 4GMXB 4HSIA 2Z0PA 5HE1A 5J3TA 5KCVA 1P5TA 4OSNA 2OQBA 3OHMB 3P7ZA 1P6SA 4KVGB 2Q13A 3NWFA 4ZRIA 1X11A 2GJYA 3PVWA 1V61A 4ZRKA 3U8ZA 1Y5OA 1ZYIA 1BAKA 1Q67A 2KGXB 2PZ1A 5I2MA 4HAUB 2LULA 3HQCA 1FHXA 3ODXA 4C0AA 4CYEA 3SUZA 1DDVA 3BINA 2DFKA 1GC6A 1MAIA 1V5UA 5L81A 3D8DA 4KHAA 3D8FA 2IYBA 1U29A 4GN1A 2XQNM 2H7DA 2J0KA 3HK0A 4A6HA 5D3XA 1MIXA 4HB4B 2UZSA 4K17A 3NWDA 3MPXA 5JHHA 2I5FA 3X23A 4A6FB 4HAXB 2N0YA 2DX1A 4OT1A 3PG7A 4HDOA 3A8QA 2ELBA 2MDXA 1FB8A 1UEFA 4DX8A 2X18A 1H4RA 1Z87A 4GNKB 3OANA 4HHVA 2J0JA 4DIXA 2CY5A 3AU5A 4QJ5B 1EAZA 3IVFA 2MKRA 3RCPA 5JHGA 1EGXA 2RUKB 3FVCA 5CLQB 1SGHA 2J59M 1X86A 5C5BA 2COFA 2D9WA 3A8PA 2LOXA 3PVUA 1MKEA 1N3HA 1MPHA 2J0MA 1XD4A 3ULCA 2OTXA 2DYQA 2RRFA 1TJ6A 2Z4DA 2P0HA 1ZC3B 1ZM0A 5CLLB 3CIKA 2KCJA 5D3VA 1WGQA 3QIJA 4DBBA 1XR0B 1EVHA 2GUMA 3QWMA 4L1RA 2W2XC 1OY2A 2CRFA 3PP2A 2H7EA 4WJ7A 2JP2A 5DI9B 1TQZA 2NMBA 4NY0A 2G35A 2CY4A 1WVHA 4YONA 1NTVA 3GYOA 2YSZA 5FI0A 2YRYA 1FHWA 2ROZB 5IRSA 1TXDA 2UVMA 1FGYA 2D9VA 4GMVA 4H8SA 1MIZB 4QXAB 1QQGA 3TO1A 4KAXB 1WJ1A 1W1DA 1ISNA 5DHAB 3TCAA 5KQ4A 1DYNA 2D9XA 1W1GA 2V76A 3MDBC 4K2PA 1AWEA 1M7EA 4MT7A 4A6KA 4D0NB 4TYZA 3NW8A 1AQCA 4GXBA 1UPRA 2W2WA 1OMWA 4HATB 4EMOA 2YS5A 1DROA 1XODA 2P8VA 2IFSA 5C5BB 2DHJA 2KUPA 2EC1A 2I1KA 2KUQA 2Y8GA 1PLSA 1LB1A 2K49A 4DX90 2NBVA 2D9ZA 2QKLA 1J19A 4MK0A 2DHKA 3DXCA 1RRPB 2LG1A 2YT2A 2KIGA 2QKMA 5HE0A 1P3RA 2UZRA 4HAVB 4L6EA 3WA0A 1U5DA 2BCJA 4Z2NA 2VKIA 3G9WA 4QJ4B 2L2IA 1KI1B 1XX0A 5KQ1A 3PSCA 3SO6A 3U7DA 2NZ8B 4GPTB 1DDMA 1X05A 1U2BA 3ODWA 3PVLA 4PQ0A 2GCJA 1K5DB 1M7RA 2DA0A 1XCGA 4CHMA 4F7HA 1OQNA 2Z59A 1V5MA 2DHIA 2D10A 5D3WA 4GZUA 3AU4A 2ROVA 3KSYA 5C16A 4HAYB 2ADZA 2R2YA 5DIFB 3UZTA 2DTCA 2LYDA 2ZPYA 3F5RA 5DH9B 5D3YA 1UNPA 2FJLA 3ZDTA 1W1HA 3T06A 4F7GA 3ODOA 2E2XA 3A58A 3A98B 3ULBA 1V5PA 2EJ8A 3M1IB 4NSWA 3CXBB 4HAZB 1H10A 4WVFB 1BTKA 1K5GB 1I2HA 1WGUA 2ZKMX 2RLOA 4IFSA 4EJNA 1FGZA 5HE3A 2HE7A 5C79A 1FHOA 4CSQA 2VSZA 5LG4B 3FM8C 2MFQA 3D8EA 3SV1A 2Z0QA 3TFMA 4K81A 2DX5A 2D4QA 4HB3B 2N23A 4PNKA 3LJUX 1BTNA 5EFXA 4KHBA 2K00A 5HE2A 1PMSA 2KIEA 1EF1A 2CAYA 2LKOA 3HW2B 4HDQA 2RGNB 5D27A 3O96A 2L1CA 2COAA 4A5KA 2M38A 1E5WA 3HIEA 4DXAB 5FI1A 4EKUA 2YS3A 2ELAA 3SNHA 1MI1A 4TKNA 5I2SA 1WJMA 4QJ3B 2I1JA 2MWNB 2COCA 2D11A 4IOYX 3B77A 4GOUA 2R0DA 1J0WA 1GG3A 3NSUA 5GOWB 1XKEA 3KZ1A 3KY9A 2LOZA 1WG7A 1ZVRA 1QC6A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4BBK A;  4CHJ A;  2RSG A;  4YL8 A;  1MK7 B;  5JLJ B;  5LON B;  1KZ7 A;  2K2U A;  3FEH A;  3ZVR A;  3V5W A;  3DXE A;  1U5F A;  1NI2 A;  3KRX A;  1NU2 A;  4IAP A;  2M14 A;  1MK9 B;  2DLW A;  2RVB B;  4MY6 A;  2W2X D;  1U27 A;  1X1G A;  3N7C A;  2K2J A;  1UNQ A;  3VIA A;  1V88 A;  2YT0 A;  2DN6 A;  3F0W A;  2EMS A;  3GYP A;  3VOQ A;  4HB2 B;  1U5E A;  3BJI A;  2AL6 A;  4KHB B;  2AEH A;  4ZRJ A;  3DXD A;  1BWN A;  1GC7 A;  4Y94 A;  1I7A A;  2R09 A;  2P0D A;  1V89 A;  2GCL A;  3AJ4 A;  5JP4 A;  1B55 A;  3WYF B;  5C6R A;  2Y8F A;  1IRS A;  4HB0 B;  4HAW B;  3PZD A;  3TVV A;  1SHC A;  5LOP B;  1KZG A;  2DKP A;  1X1F A;  1ZC4 B;  1UPQ A;  1RJ2 A;  1FAO A;  2COD A;  4B6H A;  4KHO A;  2HTH B;  1UNR A;  1PFJ A;  2YF0 A;  2YS1 A;  2D2Q A;  4A6F A;  4F7U P;  3P6A A;  2Z0O A;  2YT1 A;  3QBV B;  4XWX A;  3ML4 A;  2YVC A;  2VRW B;  1ZSQ A;  4P7I A;  4WSF A;  2D9Y A;  2DYN A;  3KRW A;  1DBH A;  4Z2M B;  3TW1 A;  1FOE A;  2Y7B A;  1DDW A;  1LW3 A;  1Y19 B;  2P0F A;  3PEG A;  4K2O A;  3SYX A;  2GS0 A;  2DKQ A;  2EMT A;  2I5C A;  2RNR B;  1NTY A;  1U5G A;  5DHF B;  5J3Y A;  5J3Q A;  3FSS A;  1WI1 A;  4GMX B;  2Z0P A;  5HE1 A;  5J3T A;  5KCV A;  1P5T A;  2OQB A;  3P7Z A;  1P6S A;  4KVG B;  2Q13 A;  4ZRI A;  1X11 A;  2GJY A;  3PVW A;  1V61 A;  4ZRK A;  3U8Z A;  1Y5O A;  1BAK A;  1Q67 A;  2KGX B;  2PZ1 A;  4HAU B;  2LUL A;  3HQC A;  1FHX A;  3ODX A;  4C0A A;  4CYE A;  3SUZ A;  1DDV A;  3BIN A;  2DFK A;  1GC6 A;  1MAI A;  1V5U A;  5L81 A;  3D8D A;  4KHA A;  3D8F A;  2IYB A;  1U29 A;  4GN1 A;  2XQN M;  2H7D A;  2J0K A;  3HK0 A;  4A6H A;  5D3X A;  1MIX A;  4HB4 B;  2UZS A;  4K17 A;  3MPX A;  5JHH A;  2I5F A;  3X23 A;  4A6F B;  4HAX B;  2N0Y A;  2DX1 A;  3PG7 A;  4HDO A;  3A8Q A;  2ELB A;  2MDX A;  1FB8 A;  1UEF A;  4DX8 A;  2X18 A;  1H4R A;  1Z87 A;  3OAN A;  4HHV A;  2J0J A;  2CY5 A;  3AU5 A;  1EAZ A;  3IVF A;  2MKR A;  3RCP A;  5JHG A;  1EGX A;  2RUK B;  5CLQ B;  1SGH A;  2J59 M;  1X86 A;  5C5B A;  2COF A;  2D9W A;  3A8P A;  2LOX A;  3PVU A;  1MKE A;  1N3H A;  1MPH A;  2J0M A;  1XD4 A;  3ULC A;  2OTX A;  2DYQ A;  1TJ6 A;  2P0H A;  1ZC3 B;  1ZM0 A;  5CLL B;  3CIK A;  2KCJ A;  5D3V A;  1WGQ A;  3QIJ A;  4DBB A;  1XR0 B;  1EVH A;  3QWM A;  2W2X C;  1OY2 A;  2CRF A;  3PP2 A;  2H7E A;  4WJ7 A;  2JP2 A;  5DI9 B;  1TQZ A;  2NMB A;  4NY0 A;  2G35 A;  2CY4 A;  1WVH A;  4YON A;  1NTV A;  3GYO A;  2YSZ A;  5FI0 A;  2YRY A;  1FHW A;  2ROZ B;  1TXD A;  2UVM A;  1FGY A;  2D9V A;  4GMV A;  4H8S A;  1MIZ B;  1QQG A;  3TO1 A;  4KAX B;  1WJ1 A;  1W1D A;  1ISN A;  5DHA B;  3TCA A;  5KQ4 A;  1DYN A;  2D9X A;  1W1G A;  2V76 A;  3MDB C;  4K2P A;  1AWE A;  1M7E A;  4MT7 A;  4A6K A;  4D0N B;  4TYZ A;  1AQC A;  4GXB A;  1UPR A;  2W2W A;  1OMW A;  4HAT B;  4EMO A;  2YS5 A;  1DRO A;  1XOD A;  2P8V A;  2IFS A;  5C5B B;  2DHJ A;  2KUP A;  2EC1 A;  2I1K A;  2Y8G A;  1PLS A;  1LB1 A;  4DX9 0;  2D9Z A;  2QKL A;  1J19 A;  4MK0 A;  2DHK A;  3DXC A;  1RRP B;  2LG1 A;  2QKM A;  5HE0 A;  1P3R A;  2UZR A;  4HAV B;  4L6E A;  3WA0 A;  1U5D A;  2BCJ A;  4Z2N A;  2VKI A;  3G9W A;  2L2I A;  1KI1 B;  1XX0 A;  5KQ1 A;  3PSC A;  3SO6 A;  3U7D A;  2NZ8 B;  4GPT B;  1DDM A;  1X05 A;  3ODW A;  1U2B A;  3PVL A;  4PQ0 A;  2GCJ A;  1K5D B;  1M7R A;  2DA0 A;  1XCG A;  4CHM A;  4F7H A;  1OQN A;  1V5M A;  2DHI A;  2D10 A;  5D3W A;  4GZU A;  3AU4 A;  2ROV A;  3KSY A;  5C16 A;  4HAY B;  2ADZ A;  5DIF B;  3UZT A;  2DTC A;  2LYD A;  2ZPY A;  3F5R A;  5DH9 B;  5D3Y A;  1UNP A;  2FJL A;  3ZDT A;  1W1H A;  3T06 A;  4F7G A;  3ODO A;  2E2X A;  3A98 B;  3ULB A;  1V5P A;  2EJ8 A;  3M1I B;  4NSW A;  3CXB B;  4HAZ B;  1H10 A;  4WVF B;  1BTK A;  1K5G B;  1I2H A;  1WGU A;  2RLO A;  4IFS A;  4EJN A;  1FGZ A;  5HE3 A;  2HE7 A;  5C79 A;  1FHO A;  2VSZ A;  3FM8 C;  2MFQ A;  3D8E A;  3SV1 A;  2Z0Q A;  3TFM A;  4K81 A;  2DX5 A;  2D4Q A;  4HB3 B;  2N23 A;  4PNK A;  3LJU X;  1BTN A;  5EFX A;  2K00 A;  5HE2 A;  1PMS A;  1EF1 A;  2CAY A;  2LKO A;  3HW2 B;  4HDQ A;  2RGN B;  5D27 A;  3O96 A;  2L1C A;  2COA A;  4A5K A;  2M38 A;  1E5W A;  4DXA B;  5FI1 A;  4EKU A;  2YS3 A;  2ELA A;  3SNH A;  4TKN A;  1WJM A;  2I1J A;  2MWN B;  2COC A;  2D11 A;  4IOY X;  2R0D A;  1J0W A;  1GG3 A;  3NSU A;  5GOW B;  1XKE A;  3KZ1 A;  3KY9 A;  2LOZ A;  1WG7 A;  1ZVR A;  1QC6 A; 
#chains in the Genus database with same CATH topology
 4BBK A;  4CHJ A;  2RSG A;  4YL8 A;  1MK7 B;  5JLJ B;  5LON B;  1KZ7 A;  2FJU B;  2K2U A;  3FEH A;  3ZVR A;  3V5W A;  3DXE A;  1U5F A;  1NI2 A;  3KRX A;  1NU2 A;  4IAP A;  2KR0 A;  2M14 A;  1MK9 B;  2DLW A;  2RVB B;  4MY6 A;  2W2X D;  1U27 A;  1X1G A;  3N7C A;  2K2J A;  1UNQ A;  3VIA A;  1V88 A;  3U12 A;  2YT0 A;  2DN6 A;  3F0W A;  2EMS A;  3GYP A;  3VOQ A;  4HB2 B;  1U5E A;  3BJI A;  2AL6 A;  4KHB B;  2AEH A;  4ZRJ A;  3HSA A;  3NWA A;  3DXD A;  1BWN A;  1GC7 A;  4Y94 A;  1I7A A;  2R09 A;  2P0D A;  1V89 A;  2GCL A;  2Z14 A;  3AJ4 A;  5JP4 A;  1B55 A;  3WYF B;  5C6R A;  2Y8F A;  1IRS A;  4HB0 B;  4HAW B;  3PZD A;  3DCX A;  3TVV A;  1SHC A;  5LOP B;  1KZG A;  2DKP A;  1X1F A;  1ZC4 B;  1UPQ A;  1RJ2 A;  1FAO A;  2COD A;  4B6H A;  4KHO A;  2HTH B;  1UNR A;  1PFJ A;  2YF0 A;  2YS1 A;  1T77 A;  2D2Q A;  4A6F A;  4F7U P;  3P6A A;  2Z0O A;  2YT1 A;  3QBV B;  4XWX A;  3ML4 A;  2YVC A;  2VRW B;  1ZSQ A;  4P7I A;  4WSF A;  2D9Y A;  2DYN A;  3KRW A;  1DBH A;  4Z2M B;  2Z13 A;  3TW1 A;  1FOE A;  5M4Y B;  2Y7B A;  4D6W A;  1DDW A;  1LW3 A;  1Y19 B;  2P0F A;  3PEG A;  4K2O A;  3SYX A;  2K8E A;  2GS0 A;  2DKQ A;  2EMT A;  2I5C A;  2RNR B;  1NTY A;  1U5G A;  5DHF B;  5J3Y A;  5J3Q A;  3FSS A;  1WI1 A;  4GMX B;  4HSI A;  2Z0P A;  5HE1 A;  5J3T A;  5KCV A;  1P5T A;  4OSN A;  2OQB A;  3OHM B;  3P7Z A;  1P6S A;  4KVG B;  2Q13 A;  3NWF A;  4ZRI A;  1X11 A;  2GJY A;  3PVW A;  1V61 A;  4ZRK A;  3U8Z A;  1Y5O A;  1ZYI A;  1BAK A;  1Q67 A;  2KGX B;  2PZ1 A;  5I2M A;  4HAU B;  2LUL A;  3HQC A;  1FHX A;  3ODX A;  4C0A A;  4CYE A;  3SUZ A;  1DDV A;  3BIN A;  2DFK A;  1GC6 A;  1MAI A;  1V5U A;  5L81 A;  3D8D A;  4KHA A;  3D8F A;  2IYB A;  1U29 A;  4GN1 A;  2XQN M;  2H7D A;  2J0K A;  3HK0 A;  4A6H A;  5D3X A;  1MIX A;  4HB4 B;  2UZS A;  4K17 A;  3NWD A;  3MPX A;  5JHH A;  2I5F A;  3X23 A;  4A6F B;  4HAX B;  2N0Y A;  2DX1 A;  4OT1 A;  3PG7 A;  4HDO A;  3A8Q A;  2ELB A;  2MDX A;  1FB8 A;  1UEF A;  4DX8 A;  2X18 A;  1H4R A;  1Z87 A;  4GNK B;  3OAN A;  4HHV A;  2J0J A;  4DIX A;  2CY5 A;  3AU5 A;  4QJ5 B;  1EAZ A;  3IVF A;  2MKR A;  3RCP A;  5JHG A;  1EGX A;  2RUK B;  3FVC A;  5CLQ B;  1SGH A;  2J59 M;  1X86 A;  5C5B A;  2COF A;  2D9W A;  3A8P A;  2LOX A;  3PVU A;  1MKE A;  1N3H A;  1MPH A;  2J0M A;  1XD4 A;  3ULC A;  2OTX A;  2DYQ A;  2RRF A;  1TJ6 A;  2Z4D A;  2P0H A;  1ZC3 B;  1ZM0 A;  5CLL B;  3CIK A;  2KCJ A;  5D3V A;  1WGQ A;  3QIJ A;  4DBB A;  1XR0 B;  1EVH A;  2GUM A;  3QWM A;  4L1R A;  2W2X C;  1OY2 A;  2CRF A;  3PP2 A;  2H7E A;  4WJ7 A;  2JP2 A;  5DI9 B;  1TQZ A;  2NMB A;  4NY0 A;  2G35 A;  2CY4 A;  1WVH A;  4YON A;  1NTV A;  3GYO A;  2YSZ A;  5FI0 A;  2YRY A;  1FHW A;  2ROZ B;  5IRS A;  1TXD A;  2UVM A;  1FGY A;  2D9V A;  4GMV A;  4H8S A;  1MIZ B;  4QXA B;  1QQG A;  3TO1 A;  4KAX B;  1WJ1 A;  1W1D A;  1ISN A;  5DHA B;  3TCA A;  5KQ4 A;  1DYN A;  2D9X A;  1W1G A;  2V76 A;  3MDB C;  4K2P A;  1AWE A;  1M7E A;  4MT7 A;  4A6K A;  4D0N B;  4TYZ A;  3NW8 A;  1AQC A;  4GXB A;  1UPR A;  2W2W A;  1OMW A;  4HAT B;  4EMO A;  2YS5 A;  1DRO A;  1XOD A;  2P8V A;  2IFS A;  5C5B B;  2DHJ A;  2KUP A;  2EC1 A;  2I1K A;  2KUQ A;  2Y8G A;  1PLS A;  1LB1 A;  2K49 A;  4DX9 0;  2NBV A;  2D9Z A;  2QKL A;  1J19 A;  4MK0 A;  2DHK A;  3DXC A;  1RRP B;  2LG1 A;  2YT2 A;  2KIG A;  2QKM A;  5HE0 A;  1P3R A;  2UZR A;  4HAV B;  4L6E A;  3WA0 A;  1U5D A;  2BCJ A;  4Z2N A;  2VKI A;  3G9W A;  4QJ4 B;  2L2I A;  1KI1 B;  1XX0 A;  5KQ1 A;  3PSC A;  3SO6 A;  3U7D A;  2NZ8 B;  4GPT B;  1DDM A;  1X05 A;  1U2B A;  3ODW A;  3PVL A;  4PQ0 A;  2GCJ A;  1K5D B;  1M7R A;  2DA0 A;  1XCG A;  4CHM A;  4F7H A;  1OQN A;  2Z59 A;  1V5M A;  2DHI A;  2D10 A;  5D3W A;  4GZU A;  3AU4 A;  2ROV A;  3KSY A;  5C16 A;  4HAY B;  2ADZ A;  2R2Y A;  5DIF B;  3UZT A;  2DTC A;  2LYD A;  2ZPY A;  3F5R A;  5DH9 B;  5D3Y A;  1UNP A;  2FJL A;  3ZDT A;  1W1H A;  3T06 A;  4F7G A;  3ODO A;  2E2X A;  3A58 A;  3A98 B;  3ULB A;  1V5P A;  2EJ8 A;  3M1I B;  4NSW A;  3CXB B;  4HAZ B;  1H10 A;  4WVF B;  1BTK A;  1K5G B;  1I2H A;  1WGU A;  2ZKM X;  2RLO A;  4IFS A;  4EJN A;  1FGZ A;  5HE3 A;  2HE7 A;  5C79 A;  1FHO A;  4CSQ A;  2VSZ A;  5LG4 B;  3FM8 C;  2MFQ A;  3D8E A;  3SV1 A;  2Z0Q A;  3TFM A;  4K81 A;  2DX5 A;  2D4Q A;  4HB3 B;  2N23 A;  4PNK A;  3LJU X;  1BTN A;  5EFX A;  4KHB A;  2K00 A;  5HE2 A;  1PMS A;  2KIE A;  1EF1 A;  2CAY A;  2LKO A;  3HW2 B;  4HDQ A;  2RGN B;  5D27 A;  3O96 A;  2L1C A;  2COA A;  4A5K A;  2M38 A;  1E5W A;  3HIE A;  4DXA B;  5FI1 A;  4EKU A;  2YS3 A;  2ELA A;  3SNH A;  1MI1 A;  4TKN A;  5I2S A;  1WJM A;  4QJ3 B;  2I1J A;  2MWN B;  2COC A;  2D11 A;  4IOY X;  3B77 A;  4GOU A;  2R0D A;  1J0W A;  1GG3 A;  3NSU A;  5GOW B;  1XKE A;  3KZ1 A;  3KY9 A;  2LOZ A;  1WG7 A;  1ZVR A;  1QC6 A; 
#chains in the Genus database with same CATH homology
 4BBK A;  4CHJ A;  2RSG A;  4YL8 A;  1MK7 B;  5JLJ B;  5LON B;  1KZ7 A;  2K2U A;  3FEH A;  3ZVR A;  3V5W A;  3DXE A;  1U5F A;  1NI2 A;  3KRX A;  1NU2 A;  4IAP A;  2M14 A;  1MK9 B;  2DLW A;  2RVB B;  4MY6 A;  2W2X D;  1U27 A;  1X1G A;  3N7C A;  2K2J A;  1UNQ A;  3VIA A;  1V88 A;  2YT0 A;  2DN6 A;  3F0W A;  2EMS A;  3GYP A;  3VOQ A;  4HB2 B;  1U5E A;  3BJI A;  2AL6 A;  4KHB B;  2AEH A;  4ZRJ A;  3DXD A;  1BWN A;  1GC7 A;  4Y94 A;  1I7A A;  2R09 A;  2P0D A;  1V89 A;  2GCL A;  3AJ4 A;  5JP4 A;  1B55 A;  3WYF B;  5C6R A;  2Y8F A;  1IRS A;  4HB0 B;  4HAW B;  3PZD A;  3TVV A;  1SHC A;  5LOP B;  1KZG A;  2DKP A;  1X1F A;  1ZC4 B;  1UPQ A;  1RJ2 A;  1FAO A;  2COD A;  4B6H A;  4KHO A;  2HTH B;  1UNR A;  1PFJ A;  2YF0 A;  2YS1 A;  2D2Q A;  4A6F A;  4F7U P;  3P6A A;  2Z0O A;  2YT1 A;  3QBV B;  4XWX A;  3ML4 A;  2YVC A;  2VRW B;  1ZSQ A;  4P7I A;  4WSF A;  2D9Y A;  2DYN A;  3KRW A;  1DBH A;  4Z2M B;  3TW1 A;  1FOE A;  2Y7B A;  1DDW A;  1LW3 A;  1Y19 B;  2P0F A;  3PEG A;  4K2O A;  3SYX A;  2GS0 A;  2DKQ A;  2EMT A;  2I5C A;  2RNR B;  1NTY A;  1U5G A;  5DHF B;  5J3Y A;  5J3Q A;  3FSS A;  1WI1 A;  4GMX B;  2Z0P A;  5HE1 A;  5J3T A;  5KCV A;  1P5T A;  2OQB A;  3P7Z A;  1P6S A;  4KVG B;  2Q13 A;  4ZRI A;  1X11 A;  2GJY A;  3PVW A;  1V61 A;  4ZRK A;  3U8Z A;  1Y5O A;  1BAK A;  1Q67 A;  2KGX B;  2PZ1 A;  4HAU B;  2LUL A;  3HQC A;  1FHX A;  3ODX A;  4C0A A;  4CYE A;  3SUZ A;  1DDV A;  3BIN A;  2DFK A;  1GC6 A;  1MAI A;  1V5U A;  5L81 A;  3D8D A;  4KHA A;  3D8F A;  2IYB A;  1U29 A;  4GN1 A;  2XQN M;  2H7D A;  2J0K A;  3HK0 A;  4A6H A;  5D3X A;  1MIX A;  4HB4 B;  2UZS A;  4K17 A;  3MPX A;  5JHH A;  2I5F A;  3X23 A;  4A6F B;  4HAX B;  2N0Y A;  2DX1 A;  3PG7 A;  4HDO A;  3A8Q A;  2ELB A;  2MDX A;  1FB8 A;  1UEF A;  4DX8 A;  2X18 A;  1H4R A;  1Z87 A;  3OAN A;  4HHV A;  2J0J A;  2CY5 A;  3AU5 A;  1EAZ A;  3IVF A;  2MKR A;  3RCP A;  5JHG A;  1EGX A;  2RUK B;  5CLQ B;  1SGH A;  2J59 M;  1X86 A;  5C5B A;  2COF A;  2D9W A;  3A8P A;  2LOX A;  3PVU A;  1MKE A;  1N3H A;  1MPH A;  2J0M A;  1XD4 A;  3ULC A;  2OTX A;  2DYQ A;  1TJ6 A;  2P0H A;  1ZC3 B;  1ZM0 A;  5CLL B;  3CIK A;  2KCJ A;  5D3V A;  1WGQ A;  3QIJ A;  4DBB A;  1XR0 B;  1EVH A;  3QWM A;  2W2X C;  1OY2 A;  2CRF A;  3PP2 A;  2H7E A;  4WJ7 A;  2JP2 A;  5DI9 B;  1TQZ A;  2NMB A;  4NY0 A;  2G35 A;  2CY4 A;  1WVH A;  4YON A;  1NTV A;  3GYO A;  2YSZ A;  5FI0 A;  2YRY A;  1FHW A;  2ROZ B;  1TXD A;  2UVM A;  1FGY A;  2D9V A;  4GMV A;  4H8S A;  1MIZ B;  1QQG A;  3TO1 A;  4KAX B;  1WJ1 A;  1W1D A;  1ISN A;  5DHA B;  3TCA A;  5KQ4 A;  1DYN A;  2D9X A;  1W1G A;  2V76 A;  3MDB C;  4K2P A;  1AWE A;  1M7E A;  4MT7 A;  4A6K A;  4D0N B;  4TYZ A;  1AQC A;  4GXB A;  1UPR A;  2W2W A;  1OMW A;  4HAT B;  4EMO A;  2YS5 A;  1DRO A;  1XOD A;  2P8V A;  2IFS A;  5C5B B;  2DHJ A;  2KUP A;  2EC1 A;  2I1K A;  2Y8G A;  1PLS A;  1LB1 A;  4DX9 0;  2D9Z A;  2QKL A;  1J19 A;  4MK0 A;  2DHK A;  3DXC A;  1RRP B;  2LG1 A;  2QKM A;  5HE0 A;  1P3R A;  2UZR A;  4HAV B;  4L6E A;  3WA0 A;  1U5D A;  2BCJ A;  4Z2N A;  2VKI A;  3G9W A;  2L2I A;  1KI1 B;  1XX0 A;  5KQ1 A;  3PSC A;  3SO6 A;  3U7D A;  2NZ8 B;  4GPT B;  1DDM A;  1X05 A;  3ODW A;  1U2B A;  3PVL A;  4PQ0 A;  2GCJ A;  1K5D B;  1M7R A;  2DA0 A;  1XCG A;  4CHM A;  4F7H A;  1OQN A;  1V5M A;  2DHI A;  2D10 A;  5D3W A;  4GZU A;  3AU4 A;  2ROV A;  3KSY A;  5C16 A;  4HAY B;  2ADZ A;  5DIF B;  3UZT A;  2DTC A;  2LYD A;  2ZPY A;  3F5R A;  5DH9 B;  5D3Y A;  1UNP A;  2FJL A;  3ZDT A;  1W1H A;  3T06 A;  4F7G A;  3ODO A;  2E2X A;  3A98 B;  3ULB A;  1V5P A;  2EJ8 A;  3M1I B;  4NSW A;  3CXB B;  4HAZ B;  1H10 A;  4WVF B;  1BTK A;  1K5G B;  1I2H A;  1WGU A;  2RLO A;  4IFS A;  4EJN A;  1FGZ A;  5HE3 A;  2HE7 A;  5C79 A;  1FHO A;  2VSZ A;  3FM8 C;  2MFQ A;  3D8E A;  3SV1 A;  2Z0Q A;  3TFM A;  4K81 A;  2DX5 A;  2D4Q A;  4HB3 B;  2N23 A;  4PNK A;  3LJU X;  1BTN A;  5EFX A;  2K00 A;  5HE2 A;  1PMS A;  1EF1 A;  2CAY A;  2LKO A;  3HW2 B;  4HDQ A;  2RGN B;  5D27 A;  3O96 A;  2L1C A;  2COA A;  4A5K A;  2M38 A;  1E5W A;  4DXA B;  5FI1 A;  4EKU A;  2YS3 A;  2ELA A;  3SNH A;  4TKN A;  1WJM A;  2I1J A;  2MWN B;  2COC A;  2D11 A;  4IOY X;  2R0D A;  1J0W A;  1GG3 A;  3NSU A;  5GOW B;  1XKE A;  3KZ1 A;  3KY9 A;  2LOZ A;  1WG7 A;  1ZVR A;  1QC6 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1M7RA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations