1MI1 | Genus

Total Genus 111

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	111
sequence length	414
structure length	414
Chain Sequence	GPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDSAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSTLSWLVRIEPFTTFFLNANDGKFDHPDRTFSSVARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYNLGVREDEVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDPVLREAMEAQIQNFGQTPSQLLIEPHPPR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Signaling protein
source organism	Homo sapiens
publication title	Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain. pubmed doi rcsb
molecule keywords	Neurobeachin
total genus	111
structure length	414
sequence length	414
chains with identical sequence	B
ec nomenclature
pdb deposition date	2002-08-21

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02138	Beach	Beige/BEACH domain
A	PF14844	PH_BEACH	PH domain associated with Beige/BEACH

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.1540.10	Mainly Alpha	Orthogonal Bundle	Neurobeachin; Chain: A, domain 1	BEACH domain	1mi1A02
2.30.29.40	Mainly Beta	Roll	PH-domain like	PH domain-like; domain 1	1mi1A01

1T77A 1MI1A
chains in the Genus database with same CATH superfamily

3U8ZA 2K2JA 1V89A 3BJIA 2Z59A 1Y5OA 3HK0A 1EVHA 2NMBA 5HE1A 2GS0A 2I1JA 2L2IA 1X11A 5C6RA 2COFA 1WG7A 4OT1A 1ZC4B 2COAA 2I1KA 5I2SA 1BWNA 5KCVA 2KCJA 2KGXB 2P0FA 2VRWB 1OY2A 4ZRIA 4HHVA 4MY6A 2AL6A 1ZYIA 4IOYX 1FHXA 4A6KA 3ODOA 3AU4A 3NSUA 1V5MA 4IFSA 2OTXA 1FOEA 4GPTB 1MK7B 1IRSA 1WVHA 2D9ZA 4TYZA 5KQ4A 2NBVA 2ELBA 4NY0A 3B77A 2DA0A 3AJ4A 3QWMA 1LW3A 1I2HA 2MDXA 1XCGA 3A8PA 5DIFB 2LKOA 4ZRJA 4QXAB 3V5WA 1MI1A 3DXDA 4YL8A 1XKEA 4CYEA 5JHGA 5FI1A 3SYXA 2K8EA 4H8SA 1K5DB 2COCA 4BBKA 1ZSQA 1V88A 4GNKB 4HB4B 2UZSA 3M1IB 1PFJA 4D6WA 1P3RA 5DH9B 1W1DA 1U5GA 4DX90 1GC7A 2BCJA 2FJUB 4CSQA 1UEFA 2ADZA 3F5RA 2EJ8A 3PZDA 1QC6A 2W2XC 2VKIA 5C5BA 4OSNA 2K2UA 1B55A 1LB1A 2Z13A 3DXEA 2CRFA 1SGHA 4A6HA 4MK0A 1SHCA 2DFKA 1W1HA 2R09A 2NZ8B 1M7EA 4KHBA 5HE0A 5LG4B 1DDWA 3FEHA 2ZKMX 5D3YA 2KIGA 2MWNB 2D9YA 4IAPA 2AEHA 2L1CA 5JHHA 5J3YA 3P7ZA 5JLJB 3U7DA 1W1GA 2MFQA 1MIXA 4HB3B 1XX0A 2YRYA 2UZRA 2ROZB 4KAXB 2D9VA 1DDVA 1RRPB 3CXBB 5KQ1A 2YF0A 4KVGB 1FGZA 2DHJA 1PLSA 5LOPB 3HQCA 2HE7A 1ZM0A 4GZUA 1UNQA 1WJ1A 2N23A 3NWAA 1Q67A 4K81A 4ZRKA 1TXDA 2DHKA 1QQGA 3X23A 4PQ0A 1OMWA 4P7IA 2H7EA 1U5FA 3VIAA 2D11A 2DKPA 2LOXA 3ULCA 5D3XA 2DX1A 3D8DA 1EGXA 5DHFB 4EMOA 2ELAA 5DHAB 1GC6A 2D9XA 1UNPA 2DHIA 4EKUA 2D2QA 3SO6A 2GJYA 3U12A 2RGNB 2P8VA 4D0NB 5D3VA 4K2OA 4TKNA 1UPRA 4DX8A 2YVCA 3PSCA 4K17A 4A6FA 1KZGA 2RSGA 2MKRA 1TQZA 3ZVRA 1WGQA 2P0DA 3FVCA 1J0WA 2ROVA 3TFMA 1NTYA 2GUMA 3FSSA 4KHAA 1DDMA 3BINA 4KHOA 3F0WA 1XODA 1T77A 4HAZB 2M14A 2D4QA 1U5EA 4DXAB 5J3TA 3SNHA 2Z4DA 5C79A 1MIZB 2YS1A 1FHOA 2RNRB 4QJ4B 4A6FB 5J3QA 1M7RA 2RUKB 1H4RA 1TJ6A 1X1FA 5C16A 5M4YB 5IRSA 1Z87A 2YS5A 1XD4A 4L1RA 2CODA 3PVLA 2RLOA 2LOZA 2J0KA 2K00A 1ISNA 1Y19B 2K49A 3ODXA 3HW2B 5CLQB 4HAWB 4HAXB 1BTNA 3PG7A 3KRWA 1BAKA 2D9WA 3SV1A 3WA0A 3UZTA 2LG1A 3HIEA 3O96A 3OANA 4PNKA 1DYNA 5HE2A 3A98B 4WJ7A 1WI1A 4DIXA 2HTHB 2M38A 2CAYA 2EC1A 3RCPA 3KZ1A 1H10A 4GOUA 2Y8FA 2EMTA 4Y94A 4C0AA 3WYFB 3OHMB 3NW8A 5C5BB 1K5GB 3A8QA 3VOQA 5L81A 1X05A 4GMXB 1V61A 2FJLA 2UVMA 1U2BA 4HAUB 3GYPA 1WGUA 5EFXA 4KHBB 2V76A 2IFSA 3PP2A 3ULBA 4A5KA 2KUQA 1MPHA 1NU2A 2D10A 1P6SA 3TW1A 2CY5A 2CY4A 2E2XA 2DN6A 2DLWA 2W2WA 5CLLB 1ZVRA 1FB8A 1GG3A 2J0JA 3TCAA 1DROA 4HB0B 1NI2A 3HSAA 1NTVA 4HSIA 4XWXA 3NWDA 2YT0A 2EMSA 4DBBA 3ML4A 4QJ3B 3QBVB 1N3HA 1EAZA 4HDQA 4HB2B 1P5TA 4F7GA 3MDBC 2I5FA 2Z14A 3PVWA 4Z2NA 1X1GA 2VSZA 2Y7BA 1E5WA 3GYOA 5D3WA 5GOWB 3CIKA 1AQCA 1DBHA 2KR0A 2I5CA 1MAIA 2YS3A 2YSZA 5D27A 2DTCA 2Z0QA 2GCLA 3MPXA 2Q13A 2IYBA 2RRFA 3KY9A 4YONA 4CHJA 1V5PA 1WJMA 2DYNA 3P6AA 1I7AA 4GXBA 1J19A 4HDOA 3ODWA 3TVVA 2Z0OA 3N7CA 2LYDA 2QKLA 4K2PA 2GCJA 4MT7A 1MK9B 3FM8C 4WSFA 2DX5A 2QKMA 4WVFB 4GMVA 1XR0B 2Y8GA 2R0DA 4NSWA 3LJUX 3TO1A 1FHWA 2Z0PA 2W2XD 2YT2A 4EJNA 3SUZA 2PZ1A 1BTKA 4L6EA 2X18A 2DKQA 1MKEA 3AU5A 4CHMA 4HAVB 3ZDTA 4F7UP 1ZC3B 1UPQA 1V5UA 2JP2A 3NWFA 1UNRA 5JP4A 3PEGA 1U29A 3DXCA 3QIJA 3T06A 2J59M 2OQBA 1KZ7A 1EF1A 2R2YA 5I2MA 1FAOA 2RVBB 4F7HA 2KUPA 2G35A 1U5DA 4QJ5B 5DI9B 1X86A 2J0MA 2KIEA 2DYQA 1OQNA 3PVUA 1RJ2A 1PMSA 2LULA 2XQNM 3KSYA 4HATB 3A58A 3G9WA 2P0HA 4Z2MB 5HE3A 2YT1A 4GN1A 3IVFA 3KRXA 2H7DA 3DCXA 1KI1B 3D8EA 3D8FA 1U27A 4B6HA 5LONB 4HAYB 5FI0A 2ZPYA 1FGYA 2N0YA 1AWEA
chains in the Genus database with same CATH topology

1T77A 1MI1A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1T77 A;  1MI1 A; 
#chains in the Genus database with same CATH topology
 3U8Z A;  2K2J A;  1V89 A;  3BJI A;  2Z59 A;  1Y5O A;  3HK0 A;  1EVH A;  2NMB A;  5HE1 A;  2GS0 A;  2I1J A;  2L2I A;  1X11 A;  5C6R A;  2COF A;  1WG7 A;  4OT1 A;  1ZC4 B;  2COA A;  2I1K A;  5I2S A;  1BWN A;  5KCV A;  2KCJ A;  2KGX B;  2P0F A;  2VRW B;  1OY2 A;  4ZRI A;  4HHV A;  4MY6 A;  2AL6 A;  1ZYI A;  4IOY X;  1FHX A;  4A6K A;  3ODO A;  3AU4 A;  3NSU A;  1V5M A;  4IFS A;  2OTX A;  1FOE A;  4GPT B;  1MK7 B;  1IRS A;  1WVH A;  2D9Z A;  4TYZ A;  5KQ4 A;  2NBV A;  2ELB A;  4NY0 A;  3B77 A;  2DA0 A;  3AJ4 A;  3QWM A;  1LW3 A;  1I2H A;  2MDX A;  1XCG A;  3A8P A;  5DIF B;  2LKO A;  4ZRJ A;  4QXA B;  3V5W A;  1MI1 A;  3DXD A;  4YL8 A;  1XKE A;  4CYE A;  5JHG A;  5FI1 A;  3SYX A;  2K8E A;  4H8S A;  1K5D B;  2COC A;  4BBK A;  1ZSQ A;  1V88 A;  4GNK B;  4HB4 B;  2UZS A;  3M1I B;  1PFJ A;  4D6W A;  1P3R A;  5DH9 B;  1W1D A;  1U5G A;  4DX9 0;  1GC7 A;  2BCJ A;  2FJU B;  4CSQ A;  1UEF A;  2ADZ A;  3F5R A;  2EJ8 A;  3PZD A;  1QC6 A;  2W2X C;  2VKI A;  5C5B A;  4OSN A;  2K2U A;  1B55 A;  1LB1 A;  2Z13 A;  3DXE A;  2CRF A;  1SGH A;  4A6H A;  4MK0 A;  1SHC A;  2DFK A;  1W1H A;  2R09 A;  2NZ8 B;  1M7E A;  4KHB A;  5HE0 A;  5LG4 B;  1DDW A;  3FEH A;  2ZKM X;  5D3Y A;  2KIG A;  2MWN B;  2D9Y A;  4IAP A;  2AEH A;  2L1C A;  5JHH A;  5J3Y A;  3P7Z A;  5JLJ B;  3U7D A;  1W1G A;  2MFQ A;  1MIX A;  4HB3 B;  1XX0 A;  2YRY A;  2UZR A;  2ROZ B;  4KAX B;  2D9V A;  1DDV A;  1RRP B;  3CXB B;  5KQ1 A;  2YF0 A;  4KVG B;  1FGZ A;  2DHJ A;  1PLS A;  5LOP B;  3HQC A;  2HE7 A;  1ZM0 A;  4GZU A;  1UNQ A;  1WJ1 A;  2N23 A;  3NWA A;  1Q67 A;  4K81 A;  4ZRK A;  1TXD A;  2DHK A;  1QQG A;  3X23 A;  4PQ0 A;  1OMW A;  4P7I A;  2H7E A;  1U5F A;  3VIA A;  2D11 A;  2DKP A;  2LOX A;  3ULC A;  5D3X A;  2DX1 A;  3D8D A;  1EGX A;  5DHF B;  4EMO A;  2ELA A;  5DHA B;  1GC6 A;  2D9X A;  1UNP A;  2DHI A;  4EKU A;  2D2Q A;  3SO6 A;  2GJY A;  3U12 A;  2RGN B;  2P8V A;  4D0N B;  5D3V A;  4K2O A;  4TKN A;  1UPR A;  4DX8 A;  2YVC A;  3PSC A;  4K17 A;  4A6F A;  1KZG A;  2RSG A;  2MKR A;  1TQZ A;  3ZVR A;  1WGQ A;  2P0D A;  3FVC A;  1J0W A;  2ROV A;  3TFM A;  1NTY A;  2GUM A;  3FSS A;  4KHA A;  1DDM A;  3BIN A;  4KHO A;  3F0W A;  1XOD A;  1T77 A;  4HAZ B;  2M14 A;  2D4Q A;  1U5E A;  4DXA B;  5J3T A;  3SNH A;  2Z4D A;  5C79 A;  1MIZ B;  2YS1 A;  1FHO A;  2RNR B;  4QJ4 B;  4A6F B;  5J3Q A;  1M7R A;  2RUK B;  1H4R A;  1TJ6 A;  1X1F A;  5C16 A;  5M4Y B;  5IRS A;  1Z87 A;  2YS5 A;  1XD4 A;  4L1R A;  2COD A;  3PVL A;  2RLO A;  2LOZ A;  2J0K A;  2K00 A;  1ISN A;  1Y19 B;  2K49 A;  3ODX A;  3HW2 B;  5CLQ B;  4HAW B;  4HAX B;  1BTN A;  3PG7 A;  3KRW A;  1BAK A;  2D9W A;  3SV1 A;  3WA0 A;  3UZT A;  2LG1 A;  3HIE A;  3O96 A;  3OAN A;  4PNK A;  1DYN A;  5HE2 A;  3A98 B;  4WJ7 A;  1WI1 A;  4DIX A;  2HTH B;  2M38 A;  2CAY A;  2EC1 A;  3RCP A;  3KZ1 A;  1H10 A;  4GOU A;  2Y8F A;  2EMT A;  4Y94 A;  4C0A A;  3WYF B;  3OHM B;  3NW8 A;  5C5B B;  1K5G B;  3A8Q A;  3VOQ A;  5L81 A;  1X05 A;  4GMX B;  1V61 A;  2FJL A;  2UVM A;  1U2B A;  4HAU B;  3GYP A;  1WGU A;  5EFX A;  4KHB B;  2V76 A;  2IFS A;  3PP2 A;  3ULB A;  4A5K A;  2KUQ A;  1MPH A;  1NU2 A;  2D10 A;  1P6S A;  3TW1 A;  2CY5 A;  2CY4 A;  2E2X A;  2DN6 A;  2DLW A;  2W2W A;  5CLL B;  1ZVR A;  1FB8 A;  1GG3 A;  2J0J A;  3TCA A;  1DRO A;  4HB0 B;  1NI2 A;  3HSA A;  1NTV A;  4HSI A;  4XWX A;  3NWD A;  2YT0 A;  2EMS A;  4DBB A;  3ML4 A;  4QJ3 B;  3QBV B;  1N3H A;  1EAZ A;  4HDQ A;  4HB2 B;  1P5T A;  4F7G A;  3MDB C;  2I5F A;  2Z14 A;  3PVW A;  4Z2N A;  1X1G A;  2VSZ A;  2Y7B A;  1E5W A;  3GYO A;  5D3W A;  5GOW B;  3CIK A;  1AQC A;  1DBH A;  2KR0 A;  2I5C A;  1MAI A;  2YS3 A;  2YSZ A;  5D27 A;  2DTC A;  2Z0Q A;  2GCL A;  3MPX A;  2Q13 A;  2IYB A;  2RRF A;  3KY9 A;  4YON A;  4CHJ A;  1V5P A;  1WJM A;  2DYN A;  3P6A A;  1I7A A;  4GXB A;  1J19 A;  4HDO A;  3ODW A;  3TVV A;  2Z0O A;  3N7C A;  2LYD A;  2QKL A;  4K2P A;  2GCJ A;  4MT7 A;  1MK9 B;  3FM8 C;  4WSF A;  2DX5 A;  2QKM A;  4WVF B;  4GMV A;  1XR0 B;  2Y8G A;  2R0D A;  4NSW A;  3LJU X;  3TO1 A;  1FHW A;  2Z0P A;  2W2X D;  2YT2 A;  4EJN A;  3SUZ A;  2PZ1 A;  1BTK A;  4L6E A;  2X18 A;  2DKQ A;  1MKE A;  3AU5 A;  4CHM A;  4HAV B;  3ZDT A;  4F7U P;  1ZC3 B;  1UPQ A;  1V5U A;  2JP2 A;  3NWF A;  1UNR A;  5JP4 A;  3PEG A;  1U29 A;  3DXC A;  3QIJ A;  3T06 A;  2J59 M;  2OQB A;  1KZ7 A;  1EF1 A;  2R2Y A;  5I2M A;  1FAO A;  2RVB B;  4F7H A;  2KUP A;  2G35 A;  1U5D A;  4QJ5 B;  5DI9 B;  1X86 A;  2J0M A;  2KIE A;  2DYQ A;  1OQN A;  3PVU A;  1RJ2 A;  1PMS A;  2LUL A;  2XQN M;  3KSY A;  4HAT B;  3A58 A;  3G9W A;  2P0H A;  4Z2M B;  5HE3 A;  2YT1 A;  4GN1 A;  3IVF A;  3KRX A;  2H7D A;  3DCX A;  1KI1 B;  3D8E A;  3D8F A;  1U27 A;  4B6H A;  5LON B;  4HAY B;  5FI0 A;  2ZPY A;  1FGY A;  2N0Y A;  1AWE A; 
#chains in the Genus database with same CATH homology
 1T77 A;  1MI1 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1MI1A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations