1QQGA

Crystal structure of the ph-ptb targeting region of irs-1
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
251
structure length
207
Chain Sequence
DVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHAFKEVWQVILKPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1.
pubmed doi rcsb
molecule tags Signal transduction
source organism Homo sapiens
molecule keywords INSULIN RECEPTOR SUBSTRATE 1
total genus 51
structure length 207
sequence length 251
chains with identical sequence B
ec nomenclature
pdb deposition date 1999-06-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF02174 IRS PTB domain (IRS-1 type)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1qqgA02
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1qqgA01
4MK0A 1SHCA 5D3VA 1WGUA 5HE2A 1NI2A 3KZ1A 2D9WA 1PMSA 2Y8FA 4F7HA 5JHHA 2RNRB 3IVFA 2E2XA 4EKUA 3HK0A 4A6FA 3DXEA 2YSZA 3FEHA 2MKRA 4CHJA 3ODWA 4KAXB 2MWNB 3A98B 2KUPA 1DYNA 1P3RA 3M1IB 4GMXB 2DKQA 2D9YA 4GZUA 2V76A 3BINA 2UZSA 2LKOA 2D4QA 2R09A 3KRXA 2COAA 2W2WA 4B6HA 2AL6A 2YF0A 4CYEA 5GOWB 1FGZA 3WA0A 5LONB 2RLOA 2L2IA 2UVMA 1K5DB 2PZ1A 2DN6A 2M14A 3ZVRA 3G9WA 4KHBB 3QBVB 1NTYA 2X18A 3KRWA 2YVCA 1U2BA 1V5UA 5D3WA 4TYZA 1N3HA 2Z0OA 3MDBC 1MIXA 1XCGA 5C5BA 5DHAB 1UEFA 5J3YA 3D8DA 4ZRKA 2EMSA 4H8SA 4HAUB 4WVFB 3VOQA 4CHMA 2GCJA 4HAVB 2D11A 2ROZB 4DXAB 2R0DA 1LB1A 1FOEA 2LYDA 2CRFA 4K2OA 2RGNB 4WJ7A 1P5TA 1KZ7A 5CLLB 1W1DA 2CAYA 4HAXB 5FI1A 3UZTA 2JP2A 5C16A 1WJ1A 2OQBA 4NSWA 1Z87A 1V89A 3QWMA 3SNHA 2Y7BA 1U5FA 4DBBA 5C6RA 1AWEA 2P0HA 2YT0A 1DBHA 1SGHA 4HAZB 4PQ0A 4L6EA 1ZVRA 4F7GA 4KVGB 4DX8A 3QIJA 1H4RA 1FAOA 1UNRA 1QC6A 2YS3A 2DX5A 2IFSA 2KGXB 1XX0A 1MIZB 1MK7B 1U27A 4ZRJA 1XKEA 2DX1A 5JP4A 3GYOA 2D9ZA 3D8FA 3SYXA 1ZSQA 1U5GA 1EAZA 1UNPA 2M38A 2YS1A 1U5EA 2COFA 2K00A 5KQ1A 2EC1A 2RVBB 4P7IA 2ELBA 2GCLA 4EMOA 4F7UP 3KSYA 4DX90 1FB8A 4KHOA 1PFJA 1ZC3B 1MPHA 3ULCA 5DH9B 3PEGA 1K5GB 4HB3B 4KHAA 2CY4A 4C0AA 2DFKA 1U29A 2LG1A 3LJUX 1I7AA 2J59M 2DA0A 1Y19B 2P0FA 2CY5A 1W1HA 1EVHA 1J0WA 4MT7A 4A6HA 2P0DA 5L81A 3P6AA 2RUKB 2I5FA 1M7RA 1TJ6A 3O96A 1B55A 3F0WA 4GMVA 1E5WA 2HE7A 4K2PA 1ISNA 5DI9B 1IRSA 2DHKA 1X05A 1BTKA 1X86A 2J0JA 1GG3A 4HAWB 3TCAA 1EF1A 1UNQA 2J0MA 3TFMA 4YL8A 3RCPA 3PVWA 2QKLA 4HATB 2G35A 4Z2MB 1BWNA 1M7EA 3VIAA 1X1GA 1J19A 5D27A 2HTHB 2LULA 4NY0A 2NMBA 3A8QA 2K2UA 2W2XC 3AU5A 1OMWA 3CXBB 1DROA 2MFQA 4BBKA 1DDVA 2ADZA 4IOYX 2D9XA 2DLWA 2VKIA 3KY9A 1WGQA 1NU2A 1X11A 2NZ8B 1Q67A 4Y94A 1X1FA 1UPRA 1H10A 1XD4A 1FHOA 2AEHA 2N0YA 3SV1A 5DIFB 2MDXA 1QQGA 3AU4A 3PVLA 4XWXA 5JHGA 3MPXA 1V88A 2W2XD 4HHVA 1U5DA 5KQ4A 3U8ZA 4WSFA 3P7ZA 2N23A 1P6SA 1RRPB 2D10A 2LOXA 4D0NB 2VRWB 3HW2B 1FHXA 3DXCA 5FI0A 4ZRIA 2I1KA 1MKEA 5EFXA 5DHFB 1BTNA 1TQZA 3X23A 4HB4B 3PSCA 1XODA 2ELAA 4YONA 2ROVA 1WI1A 3PZDA 1V61A 3CIKA 2H7DA 4HDOA 3ULBA 5J3QA 2DTCA 3PVUA 2YRYA 2EMTA 4A5KA 2DHJA 1DDWA 1DDMA 4HDQA 2Y8GA 1EGXA 2IYBA 3FM8C 3WYFB 4GN1A 1RJ2A 5J3TA 2D2QA 1UPQA 1I2HA 1WVHA 2H7EA 2L1CA 3AJ4A 1Y5OA 2J0KA 1ZM0A 1V5PA 4K17A 2D9VA 2FJLA 5C79A 3T06A 3HQCA 2DYNA 2YS5A 1BAKA 2BCJA 4IFSA 3TO1A 2YT1A 3OANA 4HB2B 1OQNA 3ML4A 1MAIA 3DXDA 3TVVA 1KI1B 1XR0B 1KZGA 2RSGA 4HB0B 2OTXA 2CODA 2Q13A 2GS0A 2VSZA 3BJIA 2COCA 1V5MA 4A6FB 3A8PA 3ZDTA 5LOPB 5D3XA 5HE1A 3ODOA 4HAYB 2DKPA 1NTVA 1LW3A 1WG7A 2Z0QA 5CLQB 3TW1A 1ZC4B 4IAPA 3D8EA 4PNKA 3NSUA 2ZPYA 3SO6A 1FHWA 4A6KA 2P8VA 4Z2NA 2LOZA 4K81A 2I5CA 2Z0PA 4TKNA 1OY2A 3PG7A 4MY6A 2GJYA 5D3YA 1PLSA 3V5WA 2I1JA 3FSSA 1GC7A 3ODXA 1WJMA 3U7DA 4GPTB 1AQCA 3PP2A 5HE0A 3SUZA 4EJNA 2XQNM 1MK9B 2QKMA 3GYPA 1W1GA 1TXDA 1FGYA 5JLJB 5C5BB 2DYQA 2KCJA 2UZRA 2K2JA 2EJ8A 3F5RA 2DHIA 5KCVA 5HE3A 4GXBA 1GC6A 3N7CA
chains in the Genus database with same CATH superfamily
4MK0A 1SHCA 5D3VA 1WGUA 5HE2A 1NI2A 3KZ1A 2D9WA 1PMSA 3HIEA 2Y8FA 4F7HA 5JHHA 2RNRB 3IVFA 2E2XA 4L1RA 4EKUA 3HK0A 4A6FA 3DXEA 2YSZA 3FEHA 4OSNA 2MKRA 4CHJA 2Z13A 3ODWA 4KAXB 2MWNB 3A98B 2KUPA 1DYNA 1P3RA 3M1IB 4GMXB 2DKQA 2D9YA 3N7CA 4GZUA 4QJ4B 2V76A 3BINA 2UZSA 2LKOA 2FJUB 2D4QA 2R09A 3KRXA 2COAA 2W2WA 4B6HA 2AL6A 2YF0A 2R2YA 2KIEA 4CYEA 5GOWB 1FGZA 3WA0A 5LONB 2RLOA 2L2IA 2UVMA 1K5DB 2PZ1A 2DN6A 2M14A 3ZVRA 3G9WA 4KHBB 3QBVB 1NTYA 2X18A 3KRWA 2YVCA 1U2BA 1V5UA 5D3WA 4TYZA 1N3HA 2Z0OA 3MDBC 1MIXA 1XCGA 5C5BA 5DHAB 1UEFA 3HSAA 5J3YA 3D8DA 4ZRKA 2EMSA 4H8SA 4HAUB 4WVFB 3VOQA 4CHMA 2GCJA 4HAVB 2D11A 2ROZB 4DXAB 2R0DA 5IRSA 1LB1A 1FOEA 2LYDA 2CRFA 4K2OA 2RGNB 4WJ7A 2KR0A 1P5TA 1KZ7A 5CLLB 1W1DA 2CAYA 4HAXB 5FI1A 3UZTA 2JP2A 5C16A 1WJ1A 2OQBA 4NSWA 1Z87A 1V89A 3QWMA 3SNHA 2Y7BA 1U5FA 4DBBA 5C6RA 1AWEA 2P0HA 2YT0A 1DBHA 1SGHA 4HAZB 4PQ0A 4L6EA 1ZVRA 4F7GA 4KVGB 4DX8A 3QIJA 1H4RA 1FAOA 1UNRA 1QC6A 2YS3A 2DX5A 2IFSA 2KGXB 3NW8A 1XX0A 1MIZB 1MK7B 1U27A 4ZRJA 4KHBA 1XKEA 2DX1A 5JP4A 3GYOA 2D9ZA 3D8FA 3SYXA 1ZSQA 1U5GA 1EAZA 1UNPA 2M38A 2YS1A 1U5EA 2COFA 2K00A 5KQ1A 2EC1A 2RVBB 4P7IA 2ELBA 2GCLA 4EMOA 4F7UP 3KSYA 4DX90 1FB8A 4KHOA 1PFJA 1T77A 1ZC3B 1MPHA 3ULCA 5DH9B 3PEGA 1K5GB 4HB3B 4KHAA 2CY4A 4C0AA 2DFKA 1U29A 2LG1A 3LJUX 3A58A 1I7AA 2J59M 2DA0A 1Y19B 2P0FA 3NWAA 2CY5A 1W1HA 1EVHA 1J0WA 4MT7A 4A6HA 2P0DA 5L81A 3P6AA 2RUKB 2I5FA 1M7RA 1TJ6A 3O96A 1B55A 3F0WA 4GMVA 1E5WA 2HE7A 4K2PA 1ISNA 5DI9B 1IRSA 2DHKA 1X05A 1BTKA 1X86A 2J0JA 1GG3A 4HAWB 3TCAA 1EF1A 1UNQA 2K49A 2J0MA 3TFMA 4YL8A 3RCPA 3PVWA 2QKLA 4HATB 2G35A 4Z2MB 1BWNA 1M7EA 3VIAA 1X1GA 1J19A 5D27A 2HTHB 2LULA 4NY0A 2NMBA 3A8QA 2K2UA 1MI1A 2W2XC 3AU5A 1OMWA 1DROA 2MFQA 4BBKA 1DDVA 2ADZA 4IOYX 4GNKB 2D9XA 2DLWA 2VKIA 3KY9A 1WGQA 1NU2A 1X11A 2YT2A 2NZ8B 1Q67A 4Y94A 1X1FA 1UPRA 5M4YB 1H10A 1XD4A 1FHOA 2RRFA 2AEHA 2N0YA 3SV1A 5DIFB 2MDXA 1QQGA 3AU4A 3PVLA 4XWXA 5JHGA 3MPXA 1V88A 2W2XD 4HHVA 1U5DA 5KQ4A 3U8ZA 4WSFA 3P7ZA 2N23A 2Z59A 1P6SA 1RRPB 2D10A 2LOXA 4D0NB 2VRWB 3HW2B 1FHXA 3DXCA 2Z14A 5FI0A 4ZRIA 2I1KA 4HSIA 1MKEA 5EFXA 5DHFB 2KUQA 1BTNA 1TQZA 3X23A 4HB4B 3PSCA 1XODA 2ELAA 4YONA 2ROVA 1WI1A 3CIKA 1V61A 3PZDA 2H7DA 4HDOA 4GOUA 3ULBA 5J3QA 3FVCA 2DTCA 4CSQA 3PVUA 2YRYA 2EMTA 4A5KA 2DHJA 1DDWA 1DDMA 4HDQA 2Y8GA 1EGXA 2IYBA 3FM8C 3WYFB 4GN1A 1RJ2A 4QJ5B 5J3TA 2D2QA 1UPQA 4QJ3B 1I2HA 1WVHA 2H7EA 2K8EA 2L1CA 3AJ4A 3OHMB 1Y5OA 2J0KA 1ZM0A 1V5PA 3U12A 4K17A 2D9VA 2FJLA 5C79A 3T06A 3NWDA 3HQCA 2DYNA 2YS5A 1BAKA 2BCJA 4IFSA 2KIGA 3TO1A 2YT1A 3OANA 4HB2B 1OQNA 3ML4A 3B77A 1MAIA 3DXDA 3TVVA 1KI1B 1XR0B 1KZGA 2RSGA 4HB0B 1ZYIA 2OTXA 2CODA 2Q13A 2GS0A 2VSZA 3BJIA 2COCA 1V5MA 4A6FB 3A8PA 3ZDTA 5LOPB 5LG4B 5D3XA 5HE1A 3ODOA 4HAYB 2DKPA 1NTVA 2Z4DA 1LW3A 1WG7A 2Z0QA 5CLQB 3TW1A 1ZC4B 3DCXA 4IAPA 3D8EA 4PNKA 3NSUA 2ZPYA 3SO6A 1FHWA 4A6KA 2P8VA 4Z2NA 2LOZA 4D6WA 4K81A 2I5CA 2Z0PA 4TKNA 1OY2A 3PG7A 4OT1A 4MY6A 4QXAB 2GJYA 5D3YA 1PLSA 3V5WA 2I1JA 3FSSA 1GC7A 3ODXA 1WJMA 3U7DA 2ZKMX 1AQCA 3PP2A 4GPTB 5HE0A 3SUZA 4EJNA 2XQNM 1MK9B 2QKMA 3GYPA 1W1GA 1TXDA 5I2MA 1FGYA 5JLJB 4DIXA 5C5BB 2DYQA 5I2SA 2GUMA 2KCJA 3NWFA 2UZRA 2K2JA 2EJ8A 3F5RA 2DHIA 5KCVA 5HE3A 4GXBA 1GC6A 2NBVA 3CXBB
chains in the Genus database with same CATH topology
4MK0A 1SHCA 5D3VA 1WGUA 5HE2A 1NI2A 3KZ1A 2D9WA 1PMSA 2Y8FA 4F7HA 5JHHA 2RNRB 3IVFA 2E2XA 4EKUA 3HK0A 4A6FA 3DXEA 2YSZA 3FEHA 2MKRA 4CHJA 3ODWA 4KAXB 2MWNB 3A98B 2KUPA 1DYNA 1P3RA 3M1IB 4GMXB 2DKQA 2D9YA 4GZUA 2V76A 3BINA 2UZSA 2LKOA 2D4QA 2R09A 3KRXA 2COAA 2W2WA 4B6HA 2AL6A 2YF0A 4CYEA 5GOWB 1FGZA 3WA0A 5LONB 2RLOA 2L2IA 2UVMA 1K5DB 2PZ1A 2DN6A 2M14A 3ZVRA 3G9WA 4KHBB 3QBVB 1NTYA 2X18A 3KRWA 2YVCA 1U2BA 1V5UA 5D3WA 4TYZA 1N3HA 2Z0OA 3MDBC 1MIXA 1XCGA 5C5BA 5DHAB 1UEFA 5J3YA 3D8DA 4ZRKA 2EMSA 4H8SA 4HAUB 4WVFB 3VOQA 4CHMA 2GCJA 4HAVB 2D11A 2ROZB 4DXAB 2R0DA 1LB1A 1FOEA 2LYDA 2CRFA 4K2OA 2RGNB 4WJ7A 1P5TA 1KZ7A 5CLLB 1W1DA 2CAYA 4HAXB 5FI1A 3UZTA 2JP2A 5C16A 1WJ1A 2OQBA 4NSWA 1Z87A 1V89A 3QWMA 3SNHA 2Y7BA 1U5FA 4DBBA 5C6RA 1AWEA 2P0HA 2YT0A 1DBHA 1SGHA 4HAZB 4PQ0A 4L6EA 1ZVRA 4F7GA 4KVGB 4DX8A 3QIJA 1H4RA 1FAOA 1UNRA 1QC6A 2YS3A 2DX5A 2IFSA 2KGXB 1XX0A 1MIZB 1MK7B 1U27A 4ZRJA 1XKEA 2DX1A 5JP4A 3GYOA 2D9ZA 3D8FA 3SYXA 1ZSQA 1U5GA 1EAZA 1UNPA 2M38A 2YS1A 1U5EA 2COFA 2K00A 5KQ1A 2EC1A 2RVBB 4P7IA 2ELBA 2GCLA 4EMOA 4F7UP 3KSYA 4DX90 1FB8A 4KHOA 1PFJA 1ZC3B 1MPHA 3ULCA 5DH9B 3PEGA 1K5GB 4HB3B 4KHAA 2CY4A 4C0AA 2DFKA 1U29A 2LG1A 3LJUX 1I7AA 2J59M 2DA0A 1Y19B 2P0FA 2CY5A 1W1HA 1EVHA 1J0WA 4MT7A 4A6HA 2P0DA 5L81A 3P6AA 2RUKB 2I5FA 1M7RA 1TJ6A 3O96A 1B55A 3F0WA 4GMVA 1E5WA 2HE7A 4K2PA 1ISNA 5DI9B 1IRSA 2DHKA 1X05A 1BTKA 1X86A 2J0JA 1GG3A 4HAWB 3TCAA 1EF1A 1UNQA 2J0MA 3TFMA 4YL8A 3RCPA 3PVWA 2QKLA 4HATB 2G35A 4Z2MB 1BWNA 1M7EA 3VIAA 1X1GA 1J19A 5D27A 2HTHB 2LULA 4NY0A 2NMBA 3A8QA 2K2UA 2W2XC 3AU5A 1OMWA 3CXBB 1DROA 2MFQA 4BBKA 1DDVA 2ADZA 4IOYX 2D9XA 2DLWA 2VKIA 3KY9A 1WGQA 1NU2A 1X11A 2NZ8B 1Q67A 4Y94A 1X1FA 1UPRA 1H10A 1XD4A 1FHOA 2AEHA 2N0YA 3SV1A 5DIFB 2MDXA 1QQGA 3AU4A 3PVLA 4XWXA 5JHGA 3MPXA 1V88A 2W2XD 4HHVA 1U5DA 5KQ4A 3U8ZA 4WSFA 3P7ZA 2N23A 1P6SA 1RRPB 2D10A 2LOXA 4D0NB 2VRWB 3HW2B 1FHXA 3DXCA 5FI0A 4ZRIA 2I1KA 1MKEA 5EFXA 5DHFB 1BTNA 1TQZA 3X23A 4HB4B 3PSCA 1XODA 2ELAA 4YONA 2ROVA 1WI1A 3PZDA 1V61A 3CIKA 2H7DA 4HDOA 3ULBA 5J3QA 2DTCA 3PVUA 2YRYA 2EMTA 4A5KA 2DHJA 1DDWA 1DDMA 4HDQA 2Y8GA 1EGXA 2IYBA 3FM8C 3WYFB 4GN1A 1RJ2A 5J3TA 2D2QA 1UPQA 1I2HA 1WVHA 2H7EA 2L1CA 3AJ4A 1Y5OA 2J0KA 1ZM0A 1V5PA 4K17A 2D9VA 2FJLA 5C79A 3T06A 3HQCA 2DYNA 2YS5A 1BAKA 2BCJA 4IFSA 3TO1A 2YT1A 3OANA 4HB2B 1OQNA 3ML4A 1MAIA 3DXDA 3TVVA 1KI1B 1XR0B 1KZGA 2RSGA 4HB0B 2OTXA 2CODA 2Q13A 2GS0A 2VSZA 3BJIA 2COCA 1V5MA 4A6FB 3A8PA 3ZDTA 5LOPB 5D3XA 5HE1A 3ODOA 4HAYB 2DKPA 1NTVA 1LW3A 1WG7A 2Z0QA 5CLQB 3TW1A 1ZC4B 4IAPA 3D8EA 4PNKA 3NSUA 2ZPYA 3SO6A 1FHWA 4A6KA 2P8VA 4Z2NA 2LOZA 4K81A 2I5CA 2Z0PA 4TKNA 1OY2A 3PG7A 4MY6A 2GJYA 5D3YA 1PLSA 3V5WA 2I1JA 3FSSA 1GC7A 3ODXA 1WJMA 3U7DA 4GPTB 1AQCA 3PP2A 5HE0A 3SUZA 4EJNA 2XQNM 1MK9B 2QKMA 3GYPA 1W1GA 1TXDA 1FGYA 5JLJB 5C5BB 2DYQA 2KCJA 2UZRA 2K2JA 2EJ8A 3F5RA 2DHIA 5KCVA 5HE3A 4GXBA 1GC6A 3N7CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MK0 A;  1SHC A;  5D3V A;  1WGU A;  5HE2 A;  1NI2 A;  3KZ1 A;  2D9W A;  1PMS A;  2Y8F A;  4F7H A;  5JHH A;  2RNR B;  3IVF A;  2E2X A;  4EKU A;  3HK0 A;  4A6F A;  3DXE A;  2YSZ A;  3FEH A;  2MKR A;  4CHJ A;  3ODW A;  4KAX B;  2MWN B;  3A98 B;  2KUP A;  1DYN A;  1P3R A;  3M1I B;  4GMX B;  2DKQ A;  2D9Y A;  4GZU A;  2V76 A;  3BIN A;  2UZS A;  2LKO A;  2D4Q A;  2R09 A;  3KRX A;  2COA A;  2W2W A;  4B6H A;  2AL6 A;  2YF0 A;  4CYE A;  5GOW B;  1FGZ A;  3WA0 A;  5LON B;  2RLO A;  2L2I A;  2UVM A;  1K5D B;  2PZ1 A;  2DN6 A;  2M14 A;  3ZVR A;  3G9W A;  4KHB B;  3QBV B;  1NTY A;  2X18 A;  3KRW A;  2YVC A;  1U2B A;  1V5U A;  5D3W A;  4TYZ A;  1N3H A;  2Z0O A;  3MDB C;  1MIX A;  1XCG A;  5C5B A;  5DHA B;  1UEF A;  5J3Y A;  3D8D A;  4ZRK A;  2EMS A;  4H8S A;  4HAU B;  4WVF B;  3VOQ A;  4CHM A;  2GCJ A;  4HAV B;  2D11 A;  2ROZ B;  4DXA B;  2R0D A;  1LB1 A;  1FOE A;  2LYD A;  2CRF A;  4K2O A;  2RGN B;  4WJ7 A;  1P5T A;  1KZ7 A;  5CLL B;  1W1D A;  2CAY A;  4HAX B;  5FI1 A;  3UZT A;  2JP2 A;  5C16 A;  1WJ1 A;  2OQB A;  4NSW A;  1Z87 A;  1V89 A;  3QWM A;  3SNH A;  2Y7B A;  1U5F A;  4DBB A;  5C6R A;  1AWE A;  2P0H A;  2YT0 A;  1DBH A;  1SGH A;  4HAZ B;  4PQ0 A;  4L6E A;  1ZVR A;  4F7G A;  4KVG B;  4DX8 A;  3QIJ A;  1H4R A;  1FAO A;  1UNR A;  1QC6 A;  2YS3 A;  2DX5 A;  2IFS A;  2KGX B;  1XX0 A;  1MIZ B;  1MK7 B;  1U27 A;  4ZRJ A;  1XKE A;  2DX1 A;  5JP4 A;  3GYO A;  2D9Z A;  3D8F A;  3SYX A;  1ZSQ A;  1U5G A;  1EAZ A;  1UNP A;  2M38 A;  2YS1 A;  1U5E A;  2COF A;  2K00 A;  5KQ1 A;  2EC1 A;  2RVB B;  4P7I A;  2ELB A;  2GCL A;  4EMO A;  4F7U P;  3KSY A;  4DX9 0;  1FB8 A;  4KHO A;  1PFJ A;  1ZC3 B;  1MPH A;  3ULC A;  5DH9 B;  3PEG A;  1K5G B;  4HB3 B;  4KHA A;  2CY4 A;  4C0A A;  2DFK A;  1U29 A;  2LG1 A;  3LJU X;  1I7A A;  2J59 M;  2DA0 A;  1Y19 B;  2P0F A;  2CY5 A;  1W1H A;  1EVH A;  1J0W A;  4MT7 A;  4A6H A;  2P0D A;  5L81 A;  3P6A A;  2RUK B;  2I5F A;  1M7R A;  1TJ6 A;  3O96 A;  1B55 A;  3F0W A;  4GMV A;  1E5W A;  2HE7 A;  4K2P A;  1ISN A;  5DI9 B;  1IRS A;  2DHK A;  1X05 A;  1BTK A;  1X86 A;  2J0J A;  1GG3 A;  4HAW B;  3TCA A;  1EF1 A;  1UNQ A;  2J0M A;  3TFM A;  4YL8 A;  3RCP A;  3PVW A;  2QKL A;  4HAT B;  2G35 A;  4Z2M B;  1BWN A;  1M7E A;  3VIA A;  1X1G A;  1J19 A;  5D27 A;  2HTH B;  2LUL A;  4NY0 A;  2NMB A;  3A8Q A;  2K2U A;  2W2X C;  3AU5 A;  1OMW A;  3CXB B;  1DRO A;  2MFQ A;  4BBK A;  1DDV A;  2ADZ A;  4IOY X;  2D9X A;  2DLW A;  2VKI A;  3KY9 A;  1WGQ A;  1NU2 A;  1X11 A;  2NZ8 B;  1Q67 A;  4Y94 A;  1X1F A;  1UPR A;  1H10 A;  1XD4 A;  1FHO A;  2AEH A;  2N0Y A;  3SV1 A;  5DIF B;  2MDX A;  1QQG A;  3AU4 A;  3PVL A;  4XWX A;  5JHG A;  3MPX A;  1V88 A;  2W2X D;  4HHV A;  1U5D A;  5KQ4 A;  3U8Z A;  4WSF A;  3P7Z A;  2N23 A;  1P6S A;  1RRP B;  2D10 A;  2LOX A;  4D0N B;  2VRW B;  3HW2 B;  1FHX A;  3DXC A;  5FI0 A;  4ZRI A;  2I1K A;  1MKE A;  5EFX A;  5DHF B;  1BTN A;  1TQZ A;  3X23 A;  4HB4 B;  3PSC A;  1XOD A;  2ELA A;  4YON A;  2ROV A;  1WI1 A;  3PZD A;  1V61 A;  3CIK A;  2H7D A;  4HDO A;  3ULB A;  5J3Q A;  2DTC A;  3PVU A;  2YRY A;  2EMT A;  4A5K A;  2DHJ A;  1DDW A;  1DDM A;  4HDQ A;  2Y8G A;  1EGX A;  2IYB A;  3FM8 C;  3WYF B;  4GN1 A;  1RJ2 A;  5J3T A;  2D2Q A;  1UPQ A;  1I2H A;  1WVH A;  2H7E A;  2L1C A;  3AJ4 A;  1Y5O A;  2J0K A;  1ZM0 A;  1V5P A;  4K17 A;  2D9V A;  2FJL A;  5C79 A;  3T06 A;  3HQC A;  2DYN A;  2YS5 A;  1BAK A;  2BCJ A;  4IFS A;  3TO1 A;  2YT1 A;  3OAN A;  4HB2 B;  1OQN A;  3ML4 A;  1MAI A;  3DXD A;  3TVV A;  1KI1 B;  1XR0 B;  1KZG A;  2RSG A;  4HB0 B;  2OTX A;  2COD A;  2Q13 A;  2GS0 A;  2VSZ A;  3BJI A;  2COC A;  1V5M A;  4A6F B;  3A8P A;  3ZDT A;  5LOP B;  5D3X A;  5HE1 A;  3ODO A;  4HAY B;  2DKP A;  1NTV A;  1LW3 A;  1WG7 A;  2Z0Q A;  5CLQ B;  3TW1 A;  1ZC4 B;  4IAP A;  3D8E A;  4PNK A;  3NSU A;  2ZPY A;  3SO6 A;  1FHW A;  4A6K A;  2P8V A;  4Z2N A;  2LOZ A;  4K81 A;  2I5C A;  2Z0P A;  4TKN A;  1OY2 A;  3PG7 A;  4MY6 A;  2GJY A;  5D3Y A;  1PLS A;  3V5W A;  2I1J A;  3FSS A;  1GC7 A;  3ODX A;  1WJM A;  3U7D A;  4GPT B;  1AQC A;  3PP2 A;  5HE0 A;  3SUZ A;  4EJN A;  2XQN M;  1MK9 B;  2QKM A;  3GYP A;  1W1G A;  1TXD A;  1FGY A;  5JLJ B;  5C5B B;  2DYQ A;  2KCJ A;  2UZR A;  2K2J A;  2EJ8 A;  3F5R A;  2DHI A;  5KCV A;  5HE3 A;  4GXB A;  1GC6 A;  3N7C A; 
#chains in the Genus database with same CATH topology
 4MK0 A;  1SHC A;  5D3V A;  1WGU A;  5HE2 A;  1NI2 A;  3KZ1 A;  2D9W A;  1PMS A;  3HIE A;  2Y8F A;  4F7H A;  5JHH A;  2RNR B;  3IVF A;  2E2X A;  4L1R A;  4EKU A;  3HK0 A;  4A6F A;  3DXE A;  2YSZ A;  3FEH A;  4OSN A;  2MKR A;  4CHJ A;  2Z13 A;  3ODW A;  4KAX B;  2MWN B;  3A98 B;  2KUP A;  1DYN A;  1P3R A;  3M1I B;  4GMX B;  2DKQ A;  2D9Y A;  3N7C A;  4GZU A;  4QJ4 B;  2V76 A;  3BIN A;  2UZS A;  2LKO A;  2FJU B;  2D4Q A;  2R09 A;  3KRX A;  2COA A;  2W2W A;  4B6H A;  2AL6 A;  2YF0 A;  2R2Y A;  2KIE A;  4CYE A;  5GOW B;  1FGZ A;  3WA0 A;  5LON B;  2RLO A;  2L2I A;  2UVM A;  1K5D B;  2PZ1 A;  2DN6 A;  2M14 A;  3ZVR A;  3G9W A;  4KHB B;  3QBV B;  1NTY A;  2X18 A;  3KRW A;  2YVC A;  1U2B A;  1V5U A;  5D3W A;  4TYZ A;  1N3H A;  2Z0O A;  3MDB C;  1MIX A;  1XCG A;  5C5B A;  5DHA B;  1UEF A;  3HSA A;  5J3Y A;  3D8D A;  4ZRK A;  2EMS A;  4H8S A;  4HAU B;  4WVF B;  3VOQ A;  4CHM A;  2GCJ A;  4HAV B;  2D11 A;  2ROZ B;  4DXA B;  2R0D A;  5IRS A;  1LB1 A;  1FOE A;  2LYD A;  2CRF A;  4K2O A;  2RGN B;  4WJ7 A;  2KR0 A;  1P5T A;  1KZ7 A;  5CLL B;  1W1D A;  2CAY A;  4HAX B;  5FI1 A;  3UZT A;  2JP2 A;  5C16 A;  1WJ1 A;  2OQB A;  4NSW A;  1Z87 A;  1V89 A;  3QWM A;  3SNH A;  2Y7B A;  1U5F A;  4DBB A;  5C6R A;  1AWE A;  2P0H A;  2YT0 A;  1DBH A;  1SGH A;  4HAZ B;  4PQ0 A;  4L6E A;  1ZVR A;  4F7G A;  4KVG B;  4DX8 A;  3QIJ A;  1H4R A;  1FAO A;  1UNR A;  1QC6 A;  2YS3 A;  2DX5 A;  2IFS A;  2KGX B;  3NW8 A;  1XX0 A;  1MIZ B;  1MK7 B;  1U27 A;  4ZRJ A;  4KHB A;  1XKE A;  2DX1 A;  5JP4 A;  3GYO A;  2D9Z A;  3D8F A;  3SYX A;  1ZSQ A;  1U5G A;  1EAZ A;  1UNP A;  2M38 A;  2YS1 A;  1U5E A;  2COF A;  2K00 A;  5KQ1 A;  2EC1 A;  2RVB B;  4P7I A;  2ELB A;  2GCL A;  4EMO A;  4F7U P;  3KSY A;  4DX9 0;  1FB8 A;  4KHO A;  1PFJ A;  1T77 A;  1ZC3 B;  1MPH A;  3ULC A;  5DH9 B;  3PEG A;  1K5G B;  4HB3 B;  4KHA A;  2CY4 A;  4C0A A;  2DFK A;  1U29 A;  2LG1 A;  3LJU X;  3A58 A;  1I7A A;  2J59 M;  2DA0 A;  1Y19 B;  2P0F A;  3NWA A;  2CY5 A;  1W1H A;  1EVH A;  1J0W A;  4MT7 A;  4A6H A;  2P0D A;  5L81 A;  3P6A A;  2RUK B;  2I5F A;  1M7R A;  1TJ6 A;  3O96 A;  1B55 A;  3F0W A;  4GMV A;  1E5W A;  2HE7 A;  4K2P A;  1ISN A;  5DI9 B;  1IRS A;  2DHK A;  1X05 A;  1BTK A;  1X86 A;  2J0J A;  1GG3 A;  4HAW B;  3TCA A;  1EF1 A;  1UNQ A;  2K49 A;  2J0M A;  3TFM A;  4YL8 A;  3RCP A;  3PVW A;  2QKL A;  4HAT B;  2G35 A;  4Z2M B;  1BWN A;  1M7E A;  3VIA A;  1X1G A;  1J19 A;  5D27 A;  2HTH B;  2LUL A;  4NY0 A;  2NMB A;  3A8Q A;  2K2U A;  1MI1 A;  2W2X C;  3AU5 A;  1OMW A;  1DRO A;  2MFQ A;  4BBK A;  1DDV A;  2ADZ A;  4IOY X;  4GNK B;  2D9X A;  2DLW A;  2VKI A;  3KY9 A;  1WGQ A;  1NU2 A;  1X11 A;  2YT2 A;  2NZ8 B;  1Q67 A;  4Y94 A;  1X1F A;  1UPR A;  5M4Y B;  1H10 A;  1XD4 A;  1FHO A;  2RRF A;  2AEH A;  2N0Y A;  3SV1 A;  5DIF B;  2MDX A;  1QQG A;  3AU4 A;  3PVL A;  4XWX A;  5JHG A;  3MPX A;  1V88 A;  2W2X D;  4HHV A;  1U5D A;  5KQ4 A;  3U8Z A;  4WSF A;  3P7Z A;  2N23 A;  2Z59 A;  1P6S A;  1RRP B;  2D10 A;  2LOX A;  4D0N B;  2VRW B;  3HW2 B;  1FHX A;  3DXC A;  2Z14 A;  5FI0 A;  4ZRI A;  2I1K A;  4HSI A;  1MKE A;  5EFX A;  5DHF B;  2KUQ A;  1BTN A;  1TQZ A;  3X23 A;  4HB4 B;  3PSC A;  1XOD A;  2ELA A;  4YON A;  2ROV A;  1WI1 A;  3CIK A;  1V61 A;  3PZD A;  2H7D A;  4HDO A;  4GOU A;  3ULB A;  5J3Q A;  3FVC A;  2DTC A;  4CSQ A;  3PVU A;  2YRY A;  2EMT A;  4A5K A;  2DHJ A;  1DDW A;  1DDM A;  4HDQ A;  2Y8G A;  1EGX A;  2IYB A;  3FM8 C;  3WYF B;  4GN1 A;  1RJ2 A;  4QJ5 B;  5J3T A;  2D2Q A;  1UPQ A;  4QJ3 B;  1I2H A;  1WVH A;  2H7E A;  2K8E A;  2L1C A;  3AJ4 A;  3OHM B;  1Y5O A;  2J0K A;  1ZM0 A;  1V5P A;  3U12 A;  4K17 A;  2D9V A;  2FJL A;  5C79 A;  3T06 A;  3NWD A;  3HQC A;  2DYN A;  2YS5 A;  1BAK A;  2BCJ A;  4IFS A;  2KIG A;  3TO1 A;  2YT1 A;  3OAN A;  4HB2 B;  1OQN A;  3ML4 A;  3B77 A;  1MAI A;  3DXD A;  3TVV A;  1KI1 B;  1XR0 B;  1KZG A;  2RSG A;  4HB0 B;  1ZYI A;  2OTX A;  2COD A;  2Q13 A;  2GS0 A;  2VSZ A;  3BJI A;  2COC A;  1V5M A;  4A6F B;  3A8P A;  3ZDT A;  5LOP B;  5LG4 B;  5D3X A;  5HE1 A;  3ODO A;  4HAY B;  2DKP A;  1NTV A;  2Z4D A;  1LW3 A;  1WG7 A;  2Z0Q A;  5CLQ B;  3TW1 A;  1ZC4 B;  3DCX A;  4IAP A;  3D8E A;  4PNK A;  3NSU A;  2ZPY A;  3SO6 A;  1FHW A;  4A6K A;  2P8V A;  4Z2N A;  2LOZ A;  4D6W A;  4K81 A;  2I5C A;  2Z0P A;  4TKN A;  1OY2 A;  3PG7 A;  4OT1 A;  4MY6 A;  4QXA B;  2GJY A;  5D3Y A;  1PLS A;  3V5W A;  2I1J A;  3FSS A;  1GC7 A;  3ODX A;  1WJM A;  3U7D A;  2ZKM X;  1AQC A;  3PP2 A;  4GPT B;  5HE0 A;  3SUZ A;  4EJN A;  2XQN M;  1MK9 B;  2QKM A;  3GYP A;  1W1G A;  1TXD A;  5I2M A;  1FGY A;  5JLJ B;  4DIX A;  5C5B B;  2DYQ A;  5I2S A;  2GUM A;  2KCJ A;  3NWF A;  2UZR A;  2K2J A;  2EJ8 A;  3F5R A;  2DHI A;  5KCV A;  5HE3 A;  4GXB A;  1GC6 A;  2NBV A;  3CXB B; 
#chains in the Genus database with same CATH homology
 4MK0 A;  1SHC A;  5D3V A;  1WGU A;  5HE2 A;  1NI2 A;  3KZ1 A;  2D9W A;  1PMS A;  2Y8F A;  4F7H A;  5JHH A;  2RNR B;  3IVF A;  2E2X A;  4EKU A;  3HK0 A;  4A6F A;  3DXE A;  2YSZ A;  3FEH A;  2MKR A;  4CHJ A;  3ODW A;  4KAX B;  2MWN B;  3A98 B;  2KUP A;  1DYN A;  1P3R A;  3M1I B;  4GMX B;  2DKQ A;  2D9Y A;  4GZU A;  2V76 A;  3BIN A;  2UZS A;  2LKO A;  2D4Q A;  2R09 A;  3KRX A;  2COA A;  2W2W A;  4B6H A;  2AL6 A;  2YF0 A;  4CYE A;  5GOW B;  1FGZ A;  3WA0 A;  5LON B;  2RLO A;  2L2I A;  2UVM A;  1K5D B;  2PZ1 A;  2DN6 A;  2M14 A;  3ZVR A;  3G9W A;  4KHB B;  3QBV B;  1NTY A;  2X18 A;  3KRW A;  2YVC A;  1U2B A;  1V5U A;  5D3W A;  4TYZ A;  1N3H A;  2Z0O A;  3MDB C;  1MIX A;  1XCG A;  5C5B A;  5DHA B;  1UEF A;  5J3Y A;  3D8D A;  4ZRK A;  2EMS A;  4H8S A;  4HAU B;  4WVF B;  3VOQ A;  4CHM A;  2GCJ A;  4HAV B;  2D11 A;  2ROZ B;  4DXA B;  2R0D A;  1LB1 A;  1FOE A;  2LYD A;  2CRF A;  4K2O A;  2RGN B;  4WJ7 A;  1P5T A;  1KZ7 A;  5CLL B;  1W1D A;  2CAY A;  4HAX B;  5FI1 A;  3UZT A;  2JP2 A;  5C16 A;  1WJ1 A;  2OQB A;  4NSW A;  1Z87 A;  1V89 A;  3QWM A;  3SNH A;  2Y7B A;  1U5F A;  4DBB A;  5C6R A;  1AWE A;  2P0H A;  2YT0 A;  1DBH A;  1SGH A;  4HAZ B;  4PQ0 A;  4L6E A;  1ZVR A;  4F7G A;  4KVG B;  4DX8 A;  3QIJ A;  1H4R A;  1FAO A;  1UNR A;  1QC6 A;  2YS3 A;  2DX5 A;  2IFS A;  2KGX B;  1XX0 A;  1MIZ B;  1MK7 B;  1U27 A;  4ZRJ A;  1XKE A;  2DX1 A;  5JP4 A;  3GYO A;  2D9Z A;  3D8F A;  3SYX A;  1ZSQ A;  1U5G A;  1EAZ A;  1UNP A;  2M38 A;  2YS1 A;  1U5E A;  2COF A;  2K00 A;  5KQ1 A;  2EC1 A;  2RVB B;  4P7I A;  2ELB A;  2GCL A;  4EMO A;  4F7U P;  3KSY A;  4DX9 0;  1FB8 A;  4KHO A;  1PFJ A;  1ZC3 B;  1MPH A;  3ULC A;  5DH9 B;  3PEG A;  1K5G B;  4HB3 B;  4KHA A;  2CY4 A;  4C0A A;  2DFK A;  1U29 A;  2LG1 A;  3LJU X;  1I7A A;  2J59 M;  2DA0 A;  1Y19 B;  2P0F A;  2CY5 A;  1W1H A;  1EVH A;  1J0W A;  4MT7 A;  4A6H A;  2P0D A;  5L81 A;  3P6A A;  2RUK B;  2I5F A;  1M7R A;  1TJ6 A;  3O96 A;  1B55 A;  3F0W A;  4GMV A;  1E5W A;  2HE7 A;  4K2P A;  1ISN A;  5DI9 B;  1IRS A;  2DHK A;  1X05 A;  1BTK A;  1X86 A;  2J0J A;  1GG3 A;  4HAW B;  3TCA A;  1EF1 A;  1UNQ A;  2J0M A;  3TFM A;  4YL8 A;  3RCP A;  3PVW A;  2QKL A;  4HAT B;  2G35 A;  4Z2M B;  1BWN A;  1M7E A;  3VIA A;  1X1G A;  1J19 A;  5D27 A;  2HTH B;  2LUL A;  4NY0 A;  2NMB A;  3A8Q A;  2K2U A;  2W2X C;  3AU5 A;  1OMW A;  3CXB B;  1DRO A;  2MFQ A;  4BBK A;  1DDV A;  2ADZ A;  4IOY X;  2D9X A;  2DLW A;  2VKI A;  3KY9 A;  1WGQ A;  1NU2 A;  1X11 A;  2NZ8 B;  1Q67 A;  4Y94 A;  1X1F A;  1UPR A;  1H10 A;  1XD4 A;  1FHO A;  2AEH A;  2N0Y A;  3SV1 A;  5DIF B;  2MDX A;  1QQG A;  3AU4 A;  3PVL A;  4XWX A;  5JHG A;  3MPX A;  1V88 A;  2W2X D;  4HHV A;  1U5D A;  5KQ4 A;  3U8Z A;  4WSF A;  3P7Z A;  2N23 A;  1P6S A;  1RRP B;  2D10 A;  2LOX A;  4D0N B;  2VRW B;  3HW2 B;  1FHX A;  3DXC A;  5FI0 A;  4ZRI A;  2I1K A;  1MKE A;  5EFX A;  5DHF B;  1BTN A;  1TQZ A;  3X23 A;  4HB4 B;  3PSC A;  1XOD A;  2ELA A;  4YON A;  2ROV A;  1WI1 A;  3PZD A;  1V61 A;  3CIK A;  2H7D A;  4HDO A;  3ULB A;  5J3Q A;  2DTC A;  3PVU A;  2YRY A;  2EMT A;  4A5K A;  2DHJ A;  1DDW A;  1DDM A;  4HDQ A;  2Y8G A;  1EGX A;  2IYB A;  3FM8 C;  3WYF B;  4GN1 A;  1RJ2 A;  5J3T A;  2D2Q A;  1UPQ A;  1I2H A;  1WVH A;  2H7E A;  2L1C A;  3AJ4 A;  1Y5O A;  2J0K A;  1ZM0 A;  1V5P A;  4K17 A;  2D9V A;  2FJL A;  5C79 A;  3T06 A;  3HQC A;  2DYN A;  2YS5 A;  1BAK A;  2BCJ A;  4IFS A;  3TO1 A;  2YT1 A;  3OAN A;  4HB2 B;  1OQN A;  3ML4 A;  1MAI A;  3DXD A;  3TVV A;  1KI1 B;  1XR0 B;  1KZG A;  2RSG A;  4HB0 B;  2OTX A;  2COD A;  2Q13 A;  2GS0 A;  2VSZ A;  3BJI A;  2COC A;  1V5M A;  4A6F B;  3A8P A;  3ZDT A;  5LOP B;  5D3X A;  5HE1 A;  3ODO A;  4HAY B;  2DKP A;  1NTV A;  1LW3 A;  1WG7 A;  2Z0Q A;  5CLQ B;  3TW1 A;  1ZC4 B;  4IAP A;  3D8E A;  4PNK A;  3NSU A;  2ZPY A;  3SO6 A;  1FHW A;  4A6K A;  2P8V A;  4Z2N A;  2LOZ A;  4K81 A;  2I5C A;  2Z0P A;  4TKN A;  1OY2 A;  3PG7 A;  4MY6 A;  2GJY A;  5D3Y A;  1PLS A;  3V5W A;  2I1J A;  3FSS A;  1GC7 A;  3ODX A;  1WJM A;  3U7D A;  4GPT B;  1AQC A;  3PP2 A;  5HE0 A;  3SUZ A;  4EJN A;  2XQN M;  1MK9 B;  2QKM A;  3GYP A;  1W1G A;  1TXD A;  1FGY A;  5JLJ B;  5C5B B;  2DYQ A;  2KCJ A;  2UZR A;  2K2J A;  2EJ8 A;  3F5R A;  2DHI A;  5KCV A;  5HE3 A;  4GXB A;  1GC6 A;  3N7C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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