1T77 | Genus

Total Genus 124

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	124
sequence length	414
structure length	414
Chain Sequence	GPVSLSTPAQLVAPSVVVKGTLSVTSSELYFEVDEEDPNFKKIDPKILAYTEGLHGKWLFTEIRSIFSRRYLLQNTALEIFMANRVAVMFNFPDPATVKKVVNFLPRVGVGTSFGLPQTRRISLASPRQLFKASNMTQRWQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEELDLTLPTNFRDLSKPIGALNPKRAAFFAERYESWEDDQVPKFHYGTHYSTASFVLAWLLRIEPFTTYFLNLQGGKFDHADRTFSSISRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVMDDGTVVSDVELPPWAKTSEEFVHINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPR

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Signaling protein
source organism	Homo sapiens
publication title	Crystal Structure of the PH-BEACH Domains of Human LRBA/BGL pubmed doi rcsb
molecule keywords	Lipopolysaccharide-responsive and beige-like anchor protein
total genus	124
structure length	414
sequence length	414
chains with identical sequence	B, C, D
ec nomenclature
pdb deposition date	2004-05-08

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02138	Beach	Beige/BEACH domain
A	PF14844	PH_BEACH	PH domain associated with Beige/BEACH

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.1540.10	Mainly Alpha	Orthogonal Bundle	Neurobeachin; Chain: A, domain 1	BEACH domain	1t77A02
2.30.29.40	Mainly Beta	Roll	PH-domain like	PH domain-like; domain 1	1t77A01

1MI1A 1T77A
chains in the Genus database with same CATH superfamily

3U7DA 2MDXA 3QWMA 2V76A 1BAKA 2YT2A 5DI9B 4HB4B 3VOQA 2ELAA 1WI1A 2JP2A 3NW8A 3PVLA 3ODOA 1OQNA 3PP2A 2LYDA 4A6FB 4TKNA 3A8PA 4WJ7A 5J3TA 1MI1A 3ODWA 4MK0A 1UNPA 1M7RA 3F5RA 2FJUB 1V5UA 2M14A 2Q13A 1EAZA 4CHJA 5C5BB 1WGQA 4HAYB 1ZVRA 3WYFB 2R2YA 3G9WA 2N23A 4NY0A 2D2QA 1NI2A 3AJ4A 2CY4A 4DBBA 1X1FA 2D9YA 4GN1A 2HTHB 1U5FA 4PQ0A 1RJ2A 4GPTB 5LONB 1U27A 2GCLA 3ZVRA 2PZ1A 1P5TA 3MPXA 1M7EA 4HAXB 5DHAB 4GXBA 3OANA 4MT7A 4OSNA 1X86A 1DBHA 3ZDTA 1Q67A 2YRYA 2X18A 1U5GA 2COFA 1IRSA 1PLSA 3GYOA 4HDQA 3P6AA 4F7GA 2EMSA 2UZSA 1W1DA 1V5MA 4HB3B 2NMBA 1FGYA 1Z87A 1UPRA 1SHCA 4KVGB 2DHKA 2G35A 4DX8A 1B55A 1ZM0A 3FEHA 1DDVA 2D11A 3QIJA 2Y8GA 2DTCA 2YS1A 2HE7A 4WSFA 2ROVA 2KIEA 3AU4A 1UNRA 3KRXA 2KR0A 2YSZA 1FAOA 4PNKA 2P8VA 3BJIA 3TVVA 1KI1B 2FJLA 5I2SA 2H7EA 2K49A 2BCJA 4ZRJA 2MWNB 1N3HA 3PVUA 4GOUA 3HK0A 2E2XA 3T06A 2RLOA 3RCPA 4EKUA 1DROA 2DX5A 2RUKB 3D8FA 4CSQA 1WVHA 2I1JA 2ZPYA 4HB2B 1Y5OA 1AQCA 4KHAA 1DYNA 1MKEA 4QXAB 5KCVA 3ML4A 5D3YA 2YT0A 4L1RA 4YONA 1MIZB 4K17A 1TJ6A 2ADZA 3DXDA 3N7CA 3P7ZA 5C6RA 4YL8A 1ZYIA 3DXCA 2KIGA 3ODXA 5GOWB 2LOXA 1EF1A 3MDBC 1ZC4B 2P0DA 2EMTA 2P0HA 2YVCA 4MY6A 5J3YA 5JHGA 1BWNA 3CIKA 1FB8A 1BTNA 1H10A 5FI1A 4Z2MB 4EMOA 1FHOA 2K8EA 1XX0A 2COCA 4GMVA 1X1GA 4HDOA 4K2OA 1J0WA 2Z13A 1MPHA 1AWEA 2J0JA 3SV1A 2I1KA 4C0AA 2YT1A 2I5FA 2KGXB 5DHFB 2H7DA 2OTXA 4DX90 1DDWA 1BTKA 4KHOA 2IFSA 1I7AA 3KY9A 2DYQA 3SYXA 1WG7A 1XKEA 3GYPA 5D3VA 5HE3A 4ZRKA 4QJ5B 2DYNA 4HAZB 1J19A 2RRFA 5I2MA 1U2BA 2YS5A 1K5DB 1DDMA 5D3XA 2CODA 3IVFA 2Y8FA 2RGNB 2COAA 1EGXA 3O96A 5JHHA 3KZ1A 1TXDA 5D27A 4HAVB 1KZ7A 1V61A 1OY2A 5IRSA 3AU5A 3M1IB 2Z4DA 3ULBA 5HE2A 4A5KA 4GZUA 4DIXA 4P7IA 3OHMB 1X05A 3FM8C 1W1HA 5FI0A 1ZC3B 2RNRB 2D10A 4HSIA 4HB0B 2L2IA 3QBVB 4A6HA 1WGUA 5CLLB 2DLWA 1T77A 4D0NB 2D9WA 2Y7BA 2YF0A 1WJ1A 1P6SA 1U5DA 2IYBA 4BBKA 3TFMA 4KHBA 1H4RA 3SUZA 1QC6A 3B77A 3NWAA 2ELBA 3PEGA 5KQ4A 1X11A 1U5EA 5J3QA 2NZ8B 2Z0OA 3PSCA 1K5GB 2CY5A 4CHMA 2DKQA 4QJ3B 2DHJA 3HW2B 1MAIA 2YS3A 2AL6A 3NWFA 1LW3A 2N0YA 1GC6A 5C5BA 4Z2NA 2QKMA 4HATB 1XCGA 3FSSA 3D8EA 1NU2A 1WJMA 4K81A 3VIAA 5C79A 2DKPA 5DH9B 3BINA 5CLQB 4GNKB 4ZRIA 4L6EA 3A98B 5HE0A 4F7HA 2DHIA 1E5WA 2KCJA 3PVWA 3TO1A 2CRFA 3NSUA 2ROZB 2Z14A 5JLJB 1TQZA 3SO6A 3LJUX 4GMXB 2EC1A 3HSAA 2P0FA 1FHXA 4OT1A 2LULA 2VSZA 2DN6A 2LOZA 1V88A 2W2XD 4A6KA 2LKOA 1PMSA 2XQNM 1FGZA 4IFSA 3U12A 1FHWA 1OMWA 2I5CA 1NTYA 2MFQA 1MK9B 3HIEA 4Y94A 1EVHA 3FVCA 1Y19B 2LG1A 4IOYX 4K2PA 3UZTA 3DCXA 2K2JA 4NSWA 2VKIA 5C16A 2GUMA 2D9ZA 4B6HA 3A58A 1GC7A 4HAWB 1LB1A 4XWXA 1UPQA 4TYZA 2D9VA 1XD4A 2ZKMX 4H8SA 2NBVA 1V5PA 3KSYA 4F7UP 2QKLA 2GCJA 4HHVA 3TCAA 3V5WA 5D3WA 1W1GA 2DX1A 3X23A 1U29A 5HE1A 1UEFA 2UZRA 1KZGA 2RVBB 2Z0QA 1RRPB 2CAYA 4D6WA 2D4QA 2UVMA 5M4YB 2M38A 1GG3A 5LG4B 1SGHA 5DIFB 3U8ZA 2L1CA 2GS0A 2R09A 5LOPB 2GJYA 1XR0B 2W2WA 4IAPA 2D9XA 4DXAB 2RSGA 2EJ8A 2KUPA 3TW1A 1ZSQA 1V89A 3NWDA 2MKRA 2R0DA 5L81A 3A8QA 1QQGA 2VRWB 2W2XC 3PG7A 1UNQA 4A6FA 2KUQA 2K00A 3D8DA 1MK7B 3DXEA 3HQCA 1MIXA 4KAXB 2AEHA 2DA0A 2J59M 4HAUB 1PFJA 1FOEA 4QJ4B 2J0MA 3F0WA 3CXBB 4WVFB 2Z0PA 2K2UA 1P3RA 1I2HA 5EFXA 3KRWA 1ISNA 4EJNA 3SNHA 3WA0A 1XODA 3ULCA 5KQ1A 5JP4A 1NTVA 4CYEA 2J0KA 2Z59A 2DFKA 3PZDA 2OQBA 4KHBB
chains in the Genus database with same CATH topology

1MI1A 1T77A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1MI1 A;  1T77 A; 
#chains in the Genus database with same CATH topology
 3U7D A;  2MDX A;  3QWM A;  2V76 A;  1BAK A;  2YT2 A;  5DI9 B;  4HB4 B;  3VOQ A;  2ELA A;  1WI1 A;  2JP2 A;  3NW8 A;  3PVL A;  3ODO A;  1OQN A;  3PP2 A;  2LYD A;  4A6F B;  4TKN A;  3A8P A;  4WJ7 A;  5J3T A;  1MI1 A;  3ODW A;  4MK0 A;  1UNP A;  1M7R A;  3F5R A;  2FJU B;  1V5U A;  2M14 A;  2Q13 A;  1EAZ A;  4CHJ A;  5C5B B;  1WGQ A;  4HAY B;  1ZVR A;  3WYF B;  2R2Y A;  3G9W A;  2N23 A;  4NY0 A;  2D2Q A;  1NI2 A;  3AJ4 A;  2CY4 A;  4DBB A;  1X1F A;  2D9Y A;  4GN1 A;  2HTH B;  1U5F A;  4PQ0 A;  1RJ2 A;  4GPT B;  5LON B;  1U27 A;  2GCL A;  3ZVR A;  2PZ1 A;  1P5T A;  3MPX A;  1M7E A;  4HAX B;  5DHA B;  4GXB A;  3OAN A;  4MT7 A;  4OSN A;  1X86 A;  1DBH A;  3ZDT A;  1Q67 A;  2YRY A;  2X18 A;  1U5G A;  2COF A;  1IRS A;  1PLS A;  3GYO A;  4HDQ A;  3P6A A;  4F7G A;  2EMS A;  2UZS A;  1W1D A;  1V5M A;  4HB3 B;  2NMB A;  1FGY A;  1Z87 A;  1UPR A;  1SHC A;  4KVG B;  2DHK A;  2G35 A;  4DX8 A;  1B55 A;  1ZM0 A;  3FEH A;  1DDV A;  2D11 A;  3QIJ A;  2Y8G A;  2DTC A;  2YS1 A;  2HE7 A;  4WSF A;  2ROV A;  2KIE A;  3AU4 A;  1UNR A;  3KRX A;  2KR0 A;  2YSZ A;  1FAO A;  4PNK A;  2P8V A;  3BJI A;  3TVV A;  1KI1 B;  2FJL A;  5I2S A;  2H7E A;  2K49 A;  2BCJ A;  4ZRJ A;  2MWN B;  1N3H A;  3PVU A;  4GOU A;  3HK0 A;  2E2X A;  3T06 A;  2RLO A;  3RCP A;  4EKU A;  1DRO A;  2DX5 A;  2RUK B;  3D8F A;  4CSQ A;  1WVH A;  2I1J A;  2ZPY A;  4HB2 B;  1Y5O A;  1AQC A;  4KHA A;  1DYN A;  1MKE A;  4QXA B;  5KCV A;  3ML4 A;  5D3Y A;  2YT0 A;  4L1R A;  4YON A;  1MIZ B;  4K17 A;  1TJ6 A;  2ADZ A;  3DXD A;  3N7C A;  3P7Z A;  5C6R A;  4YL8 A;  1ZYI A;  3DXC A;  2KIG A;  3ODX A;  5GOW B;  2LOX A;  1EF1 A;  3MDB C;  1ZC4 B;  2P0D A;  2EMT A;  2P0H A;  2YVC A;  4MY6 A;  5J3Y A;  5JHG A;  1BWN A;  3CIK A;  1FB8 A;  1BTN A;  1H10 A;  5FI1 A;  4Z2M B;  4EMO A;  1FHO A;  2K8E A;  1XX0 A;  2COC A;  4GMV A;  1X1G A;  4HDO A;  4K2O A;  1J0W A;  2Z13 A;  1MPH A;  1AWE A;  2J0J A;  3SV1 A;  2I1K A;  4C0A A;  2YT1 A;  2I5F A;  2KGX B;  5DHF B;  2H7D A;  2OTX A;  4DX9 0;  1DDW A;  1BTK A;  4KHO A;  2IFS A;  1I7A A;  3KY9 A;  2DYQ A;  3SYX A;  1WG7 A;  1XKE A;  3GYP A;  5D3V A;  5HE3 A;  4ZRK A;  4QJ5 B;  2DYN A;  4HAZ B;  1J19 A;  2RRF A;  5I2M A;  1U2B A;  2YS5 A;  1K5D B;  1DDM A;  5D3X A;  2COD A;  3IVF A;  2Y8F A;  2RGN B;  2COA A;  1EGX A;  3O96 A;  5JHH A;  3KZ1 A;  1TXD A;  5D27 A;  4HAV B;  1KZ7 A;  1V61 A;  1OY2 A;  5IRS A;  3AU5 A;  3M1I B;  2Z4D A;  3ULB A;  5HE2 A;  4A5K A;  4GZU A;  4DIX A;  4P7I A;  3OHM B;  1X05 A;  3FM8 C;  1W1H A;  5FI0 A;  1ZC3 B;  2RNR B;  2D10 A;  4HSI A;  4HB0 B;  2L2I A;  3QBV B;  4A6H A;  1WGU A;  5CLL B;  2DLW A;  1T77 A;  4D0N B;  2D9W A;  2Y7B A;  2YF0 A;  1WJ1 A;  1P6S A;  1U5D A;  2IYB A;  4BBK A;  3TFM A;  4KHB A;  1H4R A;  3SUZ A;  1QC6 A;  3B77 A;  3NWA A;  2ELB A;  3PEG A;  5KQ4 A;  1X11 A;  1U5E A;  5J3Q A;  2NZ8 B;  2Z0O A;  3PSC A;  1K5G B;  2CY5 A;  4CHM A;  2DKQ A;  4QJ3 B;  2DHJ A;  3HW2 B;  1MAI A;  2YS3 A;  2AL6 A;  3NWF A;  1LW3 A;  2N0Y A;  1GC6 A;  5C5B A;  4Z2N A;  2QKM A;  4HAT B;  1XCG A;  3FSS A;  3D8E A;  1NU2 A;  1WJM A;  4K81 A;  3VIA A;  5C79 A;  2DKP A;  5DH9 B;  3BIN A;  5CLQ B;  4GNK B;  4ZRI A;  4L6E A;  3A98 B;  5HE0 A;  4F7H A;  2DHI A;  1E5W A;  2KCJ A;  3PVW A;  3TO1 A;  2CRF A;  3NSU A;  2ROZ B;  2Z14 A;  5JLJ B;  1TQZ A;  3SO6 A;  3LJU X;  4GMX B;  2EC1 A;  3HSA A;  2P0F A;  1FHX A;  4OT1 A;  2LUL A;  2VSZ A;  2DN6 A;  2LOZ A;  1V88 A;  2W2X D;  4A6K A;  2LKO A;  1PMS A;  2XQN M;  1FGZ A;  4IFS A;  3U12 A;  1FHW A;  1OMW A;  2I5C A;  1NTY A;  2MFQ A;  1MK9 B;  3HIE A;  4Y94 A;  1EVH A;  3FVC A;  1Y19 B;  2LG1 A;  4IOY X;  4K2P A;  3UZT A;  3DCX A;  2K2J A;  4NSW A;  2VKI A;  5C16 A;  2GUM A;  2D9Z A;  4B6H A;  3A58 A;  1GC7 A;  4HAW B;  1LB1 A;  4XWX A;  1UPQ A;  4TYZ A;  2D9V A;  1XD4 A;  2ZKM X;  4H8S A;  2NBV A;  1V5P A;  3KSY A;  4F7U P;  2QKL A;  2GCJ A;  4HHV A;  3TCA A;  3V5W A;  5D3W A;  1W1G A;  2DX1 A;  3X23 A;  1U29 A;  5HE1 A;  1UEF A;  2UZR A;  1KZG A;  2RVB B;  2Z0Q A;  1RRP B;  2CAY A;  4D6W A;  2D4Q A;  2UVM A;  5M4Y B;  2M38 A;  1GG3 A;  5LG4 B;  1SGH A;  5DIF B;  3U8Z A;  2L1C A;  2GS0 A;  2R09 A;  5LOP B;  2GJY A;  1XR0 B;  2W2W A;  4IAP A;  2D9X A;  4DXA B;  2RSG A;  2EJ8 A;  2KUP A;  3TW1 A;  1ZSQ A;  1V89 A;  3NWD A;  2MKR A;  2R0D A;  5L81 A;  3A8Q A;  1QQG A;  2VRW B;  2W2X C;  3PG7 A;  1UNQ A;  4A6F A;  2KUQ A;  2K00 A;  3D8D A;  1MK7 B;  3DXE A;  3HQC A;  1MIX A;  4KAX B;  2AEH A;  2DA0 A;  2J59 M;  4HAU B;  1PFJ A;  1FOE A;  4QJ4 B;  2J0M A;  3F0W A;  3CXB B;  4WVF B;  2Z0P A;  2K2U A;  1P3R A;  1I2H A;  5EFX A;  3KRW A;  1ISN A;  4EJN A;  3SNH A;  3WA0 A;  1XOD A;  3ULC A;  5KQ1 A;  5JP4 A;  1NTV A;  4CYE A;  2J0K A;  2Z59 A;  2DFK A;  3PZD A;  2OQB A;  4KHB B; 
#chains in the Genus database with same CATH homology
 1MI1 A;  1T77 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1T77A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations