1W1GA

Crystal structure of the pdk1 pleckstrin homology (ph) domain bound to dic4-phosphatidylinositol (3,4,5)-trisphosphate
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
143
structure length
143
Chain Sequence
PLGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRYQS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insights Into the Regulation of Pdk1 by Phosphoinositides and Inositol Phosphates
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1
total genus 40
structure length 143
sequence length 143
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2004-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14593 PH_3 PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1w1gA00
2V76A 3ML4A 1P6SA 2QKLA 3QBVB 2JP2A 2KGXB 2P0DA 3FM8C 1FB8A 2LYDA 1PFJA 1FGYA 4WVFB 1W1DA 1ZVRA 1XX0A 2GS0A 1WGUA 2VSZA 3AU5A 5D27A 2NMBA 2D9VA 5D3XA 2X18A 1WG7A 2M14A 3TO1A 5KQ1A 5LONB 4TYZA 2DYQA 2RLOA 2AL6A 1UNRA 4K2OA 3A98B 2W2WA 1U5FA 1FOEA 1TJ6A 3TVVA 1LB1A 2Z0PA 2Z0QA 1V89A 3DXCA 4Z2MB 2COFA 4EKUA 3AJ4A 4CHMA 4CHJA 3KSYA 3KRWA 1PLSA 2ELBA 3MDBC 1IRSA 1UPQA 3D8EA 2I1KA 3VIAA 2CODA 1MAIA 1V5PA 5J3YA 4P7IA 3PVUA 5DHFB 3HQCA 5DHAB 4NY0A 4DX90 4PQ0A 2DLWA 1DBHA 1U2BA 4XWXA 3D8DA 5C79A 4GMVA 1BTKA 4HB4B 4YL8A 2RSGA 1X86A 1B55A 2CAYA 4MT7A 3P6AA 2DYNA 2IYBA 5LOPB 2H7DA 3SV1A 3O96A 2D9YA 2J0MA 2R0DA 4C0AA 1AQCA 3QWMA 1KZGA 2L2IA 5FI0A 3TCAA 1NTYA 1X1FA 1ZM0A 3VOQA 2K2UA 2K2JA 1XKEA 2Q13A 4GPTB 2EC1A 3PP2A 5JHGA 1KI1B 1KZ7A 2D4QA 3PVLA 4HDOA 2LULA 4DXAB 1GG3A 4WJ7A 1AWEA 3F0WA 5J3QA 2LKOA 5FI1A 1U5DA 2ZPYA 2I5CA 4HDQA 3RCPA 5JHHA 2D11A 2EJ8A 2M38A 1TQZA 2YS1A 4DX8A 2YS5A 2L1CA 2DA0A 2ADZA 4MK0A 2CY5A 1WI1A 4Z2NA 4B6HA 1DDVA 3GYOA 2LOXA 2RNRB 1EAZA 1WVHA 2K00A 1W1GA 2LG1A 3ODOA 3U7DA 2KUPA 3HK0A 5D3YA 2D9WA 2NZ8B 5DIFB 1FHWA 4EJNA 1V5UA 1Q67A 2P8VA 2Z0OA 2CY4A 1BTNA 2YT0A 3SYXA 1MK7B 3A8PA 4KVGB 4PNKA 1OQNA 1XODA 5HE1A 1XCGA 1P5TA 4EMOA 2HTHB 1BAKA 3PVWA 4HAYB 3WYFB 3ULCA 1WGQA 1X11A 4BBKA 3KRXA 1NTVA 2UVMA 4GXBA 3UZTA 2YRYA 5DH9B 1QC6A 4GMXB 5HE3A 1UEFA 3F5RA 3PZDA 3CXBB 1DROA 2I1JA 1P3RA 4HAXB 4HAVB 3N7CA 1ZC4B 2YT1A 1U27A 2G35A 2W2XD 2MWNB 1W1HA 2DX5A 1PMSA 2DHKA 1GC6A 2N23A 2IFSA 5GOWB 1DDMA 3PSCA 1LW3A 1DDWA 1Y19B 3WA0A 3LJUX 4HHVA 1MPHA 1NI2A 4K81A 2P0FA 1ISNA 4NSWA 4IFSA 2OQBA 3BINA 4HAZB 4HAWB 2YSZA 2W2XC 3U8ZA 2FJLA 1J0WA 1XD4A 4HAUB 2PZ1A 2QKMA 2P0HA 1FHXA 3M1IB 5EFXA 4F7HA 5C5BB 1MIZB 2GCJA 1K5DB 4KHOA 1DYNA 3NSUA 4MY6A 1M7EA 4K17A 2HE7A 5D3VA 2MDXA 3SNHA 4HATB 3TW1A 3D8FA 1SGHA 1BWNA 1RJ2A 3SUZA 2KCJA 1GC7A 1U5GA 4HB3B 3DXEA 4L6EA 2EMTA 4KHAA 5KCVA 5C5BA 1V5MA 3DXDA 2J59M 3TFMA 4A6FB 3OANA 3FEHA 1I7AA 1I2HA 2DX1A 2CRFA 3G9WA 1U29A 3ODXA 4A5KA 3QIJA 2ELAA 5DI9B 3ODWA 5CLLB 3V5WA 3SO6A 4GZUA 1OY2A 5JP4A 2OTXA 3HW2B 2YF0A 3MPXA 2DFKA 3T06A 4ZRKA 5J3TA 1WJMA 4IOYX 2E2XA 3ZDTA 3IVFA 2BCJA 3X23A 1TXDA 2DTCA 4A6FA 2RGNB 4HB2B 2GJYA 4ZRIA 4ZRJA 3ULBA 5L81A 1FHOA 2UZRA 2D9XA 5C16A 2AEHA 1WJ1A 5D3WA 2D10A 1UNPA 2MFQA 1Y5OA 3A8QA 1EGXA 1V88A 2MKRA 1FGZA 3KZ1A 1ZSQA 4IAPA 1MKEA 1UNQA 1EF1A 2VKIA 4F7GA 1H4RA 1ZC3B 4KAXB 4CYEA 3KY9A 4TKNA 1K5GB 3P7ZA 2XQNM 1J19A 2J0JA 4H8SA 1EVHA 1M7RA 2DKPA 4YONA 1FAOA 1U5EA 1V61A 2GCLA 1RRPB 1SHCA 2Y8FA 3ZVRA 2EMSA 4F7UP 2DKQA 1OMWA 1Z87A 4A6KA 2COCA 4A6HA 4WSFA 2RVBB 4GN1A 5KQ4A 2DHJA 2UZSA 3BJIA 3AU4A 4K2PA 2ROVA 2I5FA 5HE2A 2N0YA 2YS3A 1X05A 2R09A 3PG7A 2YVCA 1QQGA 3PEGA 1X1GA 2COAA 5C6RA 2J0KA 2Y8GA 4D0NB 4KHBB 2DHIA 2VRWB 4Y94A 2H7EA 2D2QA 1MIXA 1E5WA 2ROZB 1UPRA 4HB0B 5JLJB 1MK9B 2Y7BA 5CLQB 2LOZA 5HE0A 1H10A 3FSSA 2RUKB 2DN6A 3GYPA 1XR0B 4DBBA 2D9ZA 1N3HA 3CIKA 1NU2A
chains in the Genus database with same CATH superfamily
2V76A 3ML4A 1P6SA 2QKLA 3QBVB 2JP2A 2KGXB 2P0DA 3FM8C 1FB8A 2LYDA 5I2MA 1PFJA 1FGYA 4WVFB 1W1DA 1ZVRA 1XX0A 2GS0A 1WGUA 4OT1A 2VSZA 3AU5A 5D27A 2NMBA 1MI1A 2D9VA 5D3XA 2X18A 1WG7A 2M14A 3TO1A 5KQ1A 5LONB 4TYZA 2DYQA 2Z13A 2RLOA 2AL6A 1UNRA 4K2OA 3A98B 2W2WA 1U5FA 1FOEA 1TJ6A 3TVVA 1LB1A 2Z0PA 2Z0QA 1V89A 3DXCA 4Z2MB 2COFA 4EKUA 3AJ4A 4CHMA 4CHJA 3KSYA 3KRWA 1PLSA 2RRFA 2ELBA 3MDBC 1IRSA 1UPQA 3D8EA 2ZKMX 2I1KA 3VIAA 2CODA 1MAIA 1V5PA 5J3YA 4P7IA 3PVUA 5DHFB 3HQCA 4DIXA 5DHAB 4NY0A 4DX90 4PQ0A 2DLWA 1DBHA 1U2BA 4XWXA 2KR0A 3D8DA 5C79A 4GMVA 1BTKA 4HB4B 4YL8A 2RSGA 1X86A 1B55A 2CAYA 4MT7A 3P6AA 2DYNA 2IYBA 5LOPB 2H7DA 3SV1A 3O96A 2D9YA 4QJ5B 2J0MA 2GUMA 2R0DA 4C0AA 1AQCA 3QWMA 1KZGA 2L2IA 5FI0A 3TCAA 1NTYA 1X1FA 1ZM0A 3VOQA 2K2UA 2K2JA 1XKEA 2Q13A 4GPTB 2EC1A 2Z59A 3PP2A 5JHGA 1KI1B 1KZ7A 2D4QA 3PVLA 4HDOA 2LULA 3OHMB 3NWDA 4DXAB 1GG3A 4WJ7A 1AWEA 3F0WA 5J3QA 2LKOA 5FI1A 1U5DA 2ZPYA 2I5CA 4HDQA 3RCPA 2KIEA 5JHHA 2D11A 2EJ8A 2M38A 1TQZA 2YS1A 4DX8A 2YS5A 2L1CA 4GNKB 2DA0A 2ADZA 4MK0A 2CY5A 1WI1A 4Z2NA 4B6HA 3NWAA 1DDVA 3GYOA 2LOXA 2RNRB 1EAZA 1WVHA 2K00A 4OSNA 1W1GA 2LG1A 3ODOA 3U7DA 2KUPA 3HK0A 5D3YA 2KUQA 2D9WA 2NZ8B 5DIFB 1FHWA 4EJNA 1V5UA 1Q67A 2P8VA 2Z0OA 2CY4A 1BTNA 2YT0A 3SYXA 4L1RA 1MK7B 3A8PA 4KVGB 4PNKA 1OQNA 1XODA 5HE1A 1XCGA 1P5TA 4EMOA 2HTHB 2Z14A 1BAKA 3PVWA 4HAYB 3WYFB 3ULCA 1WGQA 1X11A 4BBKA 3KRXA 1NTVA 2UVMA 4GXBA 3UZTA 2YT2A 2YRYA 5DH9B 1QC6A 4GMXB 3HSAA 5HE3A 1UEFA 3F5RA 3PZDA 3CXBB 1DROA 2I1JA 1P3RA 4HAXB 4HAVB 3N7CA 1ZC4B 2YT1A 1U27A 2K8EA 2G35A 2W2XD 2MWNB 1W1HA 2DX5A 1PMSA 5M4YB 2DHKA 1GC6A 2N23A 2IFSA 5GOWB 1DDMA 3PSCA 1LW3A 4QJ4B 1DDWA 1Y19B 3WA0A 3LJUX 4HHVA 1MPHA 4QJ3B 1NI2A 4K81A 2P0FA 1ISNA 4NSWA 4IFSA 2OQBA 3BINA 4HAZB 4D6WA 4HAWB 2YSZA 2W2XC 3U8ZA 2FJLA 1J0WA 1XD4A 4HAUB 2PZ1A 2QKMA 2P0HA 1FHXA 3M1IB 5EFXA 4F7HA 5C5BB 1MIZB 2GCJA 1K5DB 4KHOA 1DYNA 3NSUA 4MY6A 1M7EA 4K17A 2HE7A 5D3VA 2MDXA 3SNHA 4HATB 3TW1A 3D8FA 1SGHA 1BWNA 1RJ2A 3SUZA 2KCJA 1GC7A 1ZYIA 1U5GA 4HB3B 3DXEA 4L6EA 2EMTA 4KHAA 5KCVA 5C5BA 1V5MA 3DXDA 2J59M 3TFMA 3B77A 3OANA 4A6FB 3FEHA 1I7AA 1I2HA 2DX1A 2CRFA 3G9WA 1U29A 3ODXA 4A5KA 3HIEA 3QIJA 2ELAA 5DI9B 3ODWA 5CLLB 3V5WA 3SO6A 4GZUA 1OY2A 5JP4A 2OTXA 3HW2B 2YF0A 3MPXA 2DFKA 3T06A 4ZRKA 5J3TA 1WJMA 4IOYX 2E2XA 3ZDTA 3IVFA 2BCJA 3X23A 1TXDA 2DTCA 4A6FA 2RGNB 4HB2B 2GJYA 4ZRIA 4ZRJA 3ULBA 5L81A 1FHOA 2KIGA 2UZRA 2D9XA 3DCXA 5C16A 2AEHA 1WJ1A 5D3WA 2D10A 1UNPA 2MFQA 1Y5OA 3A8QA 1EGXA 1V88A 2MKRA 1FGZA 3KZ1A 1ZSQA 4IAPA 1MKEA 1UNQA 1EF1A 2VKIA 4F7GA 1H4RA 1ZC3B 4QXAB 4KAXB 4CYEA 3KY9A 4TKNA 1K5GB 3P7ZA 2XQNM 1J19A 2J0JA 4H8SA 1EVHA 1M7RA 2DKPA 4YONA 1FAOA 1U5EA 1V61A 2GCLA 1RRPB 1SHCA 2Y8FA 3ZVRA 2EMSA 4F7UP 2DKQA 1OMWA 3FVCA 1Z87A 4A6KA 2COCA 4A6HA 4WSFA 2RVBB 4GN1A 5KQ4A 2DHJA 2R2YA 2UZSA 3BJIA 3AU4A 4K2PA 2ROVA 2I5FA 5HE2A 2N0YA 2YS3A 1X05A 2R09A 4HSIA 3PG7A 2YVCA 1QQGA 3PEGA 1X1GA 2COAA 2FJUB 5C6RA 4GOUA 2Z4DA 2J0KA 2Y8GA 4D0NB 3NWFA 4KHBB 4CSQA 1T77A 2DHIA 2VRWB 5IRSA 4Y94A 2H7EA 2D2QA 1MIXA 5LG4B 1E5WA 2ROZB 1UPRA 4HB0B 5I2SA 5JLJB 1MK9B 2Y7BA 5CLQB 2LOZA 5HE0A 1H10A 3U12A 3A58A 3FSSA 2RUKB 2DN6A 2NBVA 3GYPA 1XR0B 4DBBA 2D9ZA 3NW8A 2K49A 1N3HA 3CIKA 4KHBA 1NU2A
chains in the Genus database with same CATH topology
2V76A 3ML4A 1P6SA 2QKLA 3QBVB 2JP2A 2KGXB 2P0DA 3FM8C 1FB8A 2LYDA 1PFJA 1FGYA 4WVFB 1W1DA 1ZVRA 1XX0A 2GS0A 1WGUA 2VSZA 3AU5A 5D27A 2NMBA 2D9VA 5D3XA 2X18A 1WG7A 2M14A 3TO1A 5KQ1A 5LONB 4TYZA 2DYQA 2RLOA 2AL6A 1UNRA 4K2OA 3A98B 2W2WA 1U5FA 1FOEA 1TJ6A 3TVVA 1LB1A 2Z0PA 2Z0QA 1V89A 3DXCA 4Z2MB 2COFA 4EKUA 3AJ4A 4CHMA 4CHJA 3KSYA 3KRWA 1PLSA 2ELBA 3MDBC 1IRSA 1UPQA 3D8EA 2I1KA 3VIAA 2CODA 1MAIA 1V5PA 5J3YA 4P7IA 3PVUA 5DHFB 3HQCA 5DHAB 4NY0A 4DX90 4PQ0A 2DLWA 1DBHA 1U2BA 4XWXA 3D8DA 5C79A 4GMVA 1BTKA 4HB4B 4YL8A 2RSGA 1X86A 1B55A 2CAYA 4MT7A 3P6AA 2DYNA 2IYBA 5LOPB 2H7DA 3SV1A 3O96A 2D9YA 2J0MA 2R0DA 4C0AA 1AQCA 3QWMA 1KZGA 2L2IA 5FI0A 3TCAA 1NTYA 1X1FA 1ZM0A 3VOQA 2K2UA 2K2JA 1XKEA 2Q13A 4GPTB 2EC1A 3PP2A 5JHGA 1KI1B 1KZ7A 2D4QA 3PVLA 4HDOA 2LULA 4DXAB 1GG3A 4WJ7A 1AWEA 3F0WA 5J3QA 2LKOA 5FI1A 1U5DA 2ZPYA 2I5CA 4HDQA 3RCPA 5JHHA 2D11A 2EJ8A 2M38A 1TQZA 2YS1A 4DX8A 2YS5A 2L1CA 2DA0A 2ADZA 4MK0A 2CY5A 1WI1A 4Z2NA 4B6HA 1DDVA 3GYOA 2LOXA 2RNRB 1EAZA 1WVHA 2K00A 1W1GA 2LG1A 3ODOA 3U7DA 2KUPA 3HK0A 5D3YA 2D9WA 2NZ8B 5DIFB 1FHWA 4EJNA 1V5UA 1Q67A 2P8VA 2Z0OA 2CY4A 1BTNA 2YT0A 3SYXA 1MK7B 3A8PA 4KVGB 4PNKA 1OQNA 1XODA 5HE1A 1XCGA 1P5TA 4EMOA 2HTHB 1BAKA 3PVWA 4HAYB 3WYFB 3ULCA 1WGQA 1X11A 4BBKA 3KRXA 1NTVA 2UVMA 4GXBA 3UZTA 2YRYA 5DH9B 1QC6A 4GMXB 5HE3A 1UEFA 3F5RA 3PZDA 3CXBB 1DROA 2I1JA 1P3RA 4HAXB 4HAVB 3N7CA 1ZC4B 2YT1A 1U27A 2G35A 2W2XD 2MWNB 1W1HA 2DX5A 1PMSA 2DHKA 1GC6A 2N23A 2IFSA 5GOWB 1DDMA 3PSCA 1LW3A 1DDWA 1Y19B 3WA0A 3LJUX 4HHVA 1MPHA 1NI2A 4K81A 2P0FA 1ISNA 4NSWA 4IFSA 2OQBA 3BINA 4HAZB 4HAWB 2YSZA 2W2XC 3U8ZA 2FJLA 1J0WA 1XD4A 4HAUB 2PZ1A 2QKMA 2P0HA 1FHXA 3M1IB 5EFXA 4F7HA 5C5BB 1MIZB 2GCJA 1K5DB 4KHOA 1DYNA 3NSUA 4MY6A 1M7EA 4K17A 2HE7A 5D3VA 2MDXA 3SNHA 4HATB 3TW1A 3D8FA 1SGHA 1BWNA 1RJ2A 3SUZA 2KCJA 1GC7A 1U5GA 4HB3B 3DXEA 4L6EA 2EMTA 4KHAA 5KCVA 5C5BA 1V5MA 3DXDA 2J59M 3TFMA 4A6FB 3OANA 3FEHA 1I7AA 1I2HA 2DX1A 2CRFA 3G9WA 1U29A 3ODXA 4A5KA 3QIJA 2ELAA 5DI9B 3ODWA 5CLLB 3V5WA 3SO6A 4GZUA 1OY2A 5JP4A 2OTXA 3HW2B 2YF0A 3MPXA 2DFKA 3T06A 4ZRKA 5J3TA 1WJMA 4IOYX 2E2XA 3ZDTA 3IVFA 2BCJA 3X23A 1TXDA 2DTCA 4A6FA 2RGNB 4HB2B 2GJYA 4ZRIA 4ZRJA 3ULBA 5L81A 1FHOA 2UZRA 2D9XA 5C16A 2AEHA 1WJ1A 5D3WA 2D10A 1UNPA 2MFQA 1Y5OA 3A8QA 1EGXA 1V88A 2MKRA 1FGZA 3KZ1A 1ZSQA 4IAPA 1MKEA 1UNQA 1EF1A 2VKIA 4F7GA 1H4RA 1ZC3B 4KAXB 4CYEA 3KY9A 4TKNA 1K5GB 3P7ZA 2XQNM 1J19A 2J0JA 4H8SA 1EVHA 1M7RA 2DKPA 4YONA 1FAOA 1U5EA 1V61A 2GCLA 1RRPB 1SHCA 2Y8FA 3ZVRA 2EMSA 4F7UP 2DKQA 1OMWA 1Z87A 4A6KA 2COCA 4A6HA 4WSFA 2RVBB 4GN1A 5KQ4A 2DHJA 2UZSA 3BJIA 3AU4A 4K2PA 2ROVA 2I5FA 5HE2A 2N0YA 2YS3A 1X05A 2R09A 3PG7A 2YVCA 1QQGA 3PEGA 1X1GA 2COAA 5C6RA 2J0KA 2Y8GA 4D0NB 4KHBB 2DHIA 2VRWB 4Y94A 2H7EA 2D2QA 1MIXA 1E5WA 2ROZB 1UPRA 4HB0B 5JLJB 1MK9B 2Y7BA 5CLQB 2LOZA 5HE0A 1H10A 3FSSA 2RUKB 2DN6A 3GYPA 1XR0B 4DBBA 2D9ZA 1N3HA 3CIKA 1NU2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V76 A;  3ML4 A;  1P6S A;  2QKL A;  3QBV B;  2JP2 A;  2KGX B;  2P0D A;  3FM8 C;  1FB8 A;  2LYD A;  1PFJ A;  1FGY A;  4WVF B;  1W1D A;  1ZVR A;  1XX0 A;  2GS0 A;  1WGU A;  2VSZ A;  3AU5 A;  5D27 A;  2NMB A;  2D9V A;  5D3X A;  2X18 A;  1WG7 A;  2M14 A;  3TO1 A;  5KQ1 A;  5LON B;  4TYZ A;  2DYQ A;  2RLO A;  2AL6 A;  1UNR A;  4K2O A;  3A98 B;  2W2W A;  1U5F A;  1FOE A;  1TJ6 A;  3TVV A;  1LB1 A;  2Z0P A;  2Z0Q A;  1V89 A;  3DXC A;  4Z2M B;  2COF A;  4EKU A;  3AJ4 A;  4CHM A;  4CHJ A;  3KSY A;  3KRW A;  1PLS A;  2ELB A;  3MDB C;  1IRS A;  1UPQ A;  3D8E A;  2I1K A;  3VIA A;  2COD A;  1MAI A;  1V5P A;  5J3Y A;  4P7I A;  3PVU A;  5DHF B;  3HQC A;  5DHA B;  4NY0 A;  4DX9 0;  4PQ0 A;  2DLW A;  1DBH A;  1U2B A;  4XWX A;  3D8D A;  5C79 A;  4GMV A;  1BTK A;  4HB4 B;  4YL8 A;  2RSG A;  1X86 A;  1B55 A;  2CAY A;  4MT7 A;  3P6A A;  2DYN A;  2IYB A;  5LOP B;  2H7D A;  3SV1 A;  3O96 A;  2D9Y A;  2J0M A;  2R0D A;  4C0A A;  1AQC A;  3QWM A;  1KZG A;  2L2I A;  5FI0 A;  3TCA A;  1NTY A;  1X1F A;  1ZM0 A;  3VOQ A;  2K2U A;  2K2J A;  1XKE A;  2Q13 A;  4GPT B;  2EC1 A;  3PP2 A;  5JHG A;  1KI1 B;  1KZ7 A;  2D4Q A;  3PVL A;  4HDO A;  2LUL A;  4DXA B;  1GG3 A;  4WJ7 A;  1AWE A;  3F0W A;  5J3Q A;  2LKO A;  5FI1 A;  1U5D A;  2ZPY A;  2I5C A;  4HDQ A;  3RCP A;  5JHH A;  2D11 A;  2EJ8 A;  2M38 A;  1TQZ A;  2YS1 A;  4DX8 A;  2YS5 A;  2L1C A;  2DA0 A;  2ADZ A;  4MK0 A;  2CY5 A;  1WI1 A;  4Z2N A;  4B6H A;  1DDV A;  3GYO A;  2LOX A;  2RNR B;  1EAZ A;  1WVH A;  2K00 A;  1W1G A;  2LG1 A;  3ODO A;  3U7D A;  2KUP A;  3HK0 A;  5D3Y A;  2D9W A;  2NZ8 B;  5DIF B;  1FHW A;  4EJN A;  1V5U A;  1Q67 A;  2P8V A;  2Z0O A;  2CY4 A;  1BTN A;  2YT0 A;  3SYX A;  1MK7 B;  3A8P A;  4KVG B;  4PNK A;  1OQN A;  1XOD A;  5HE1 A;  1XCG A;  1P5T A;  4EMO A;  2HTH B;  1BAK A;  3PVW A;  4HAY B;  3WYF B;  3ULC A;  1WGQ A;  1X11 A;  4BBK A;  3KRX A;  1NTV A;  2UVM A;  4GXB A;  3UZT A;  2YRY A;  5DH9 B;  1QC6 A;  4GMX B;  5HE3 A;  1UEF A;  3F5R A;  3PZD A;  3CXB B;  1DRO A;  2I1J A;  1P3R A;  4HAX B;  4HAV B;  3N7C A;  1ZC4 B;  2YT1 A;  1U27 A;  2G35 A;  2W2X D;  2MWN B;  1W1H A;  2DX5 A;  1PMS A;  2DHK A;  1GC6 A;  2N23 A;  2IFS A;  5GOW B;  1DDM A;  3PSC A;  1LW3 A;  1DDW A;  1Y19 B;  3WA0 A;  3LJU X;  4HHV A;  1MPH A;  1NI2 A;  4K81 A;  2P0F A;  1ISN A;  4NSW A;  4IFS A;  2OQB A;  3BIN A;  4HAZ B;  4HAW B;  2YSZ A;  2W2X C;  3U8Z A;  2FJL A;  1J0W A;  1XD4 A;  4HAU B;  2PZ1 A;  2QKM A;  2P0H A;  1FHX A;  3M1I B;  5EFX A;  4F7H A;  5C5B B;  1MIZ B;  2GCJ A;  1K5D B;  4KHO A;  1DYN A;  3NSU A;  4MY6 A;  1M7E A;  4K17 A;  2HE7 A;  5D3V A;  2MDX A;  3SNH A;  4HAT B;  3TW1 A;  3D8F A;  1SGH A;  1BWN A;  1RJ2 A;  3SUZ A;  2KCJ A;  1GC7 A;  1U5G A;  4HB3 B;  3DXE A;  4L6E A;  2EMT A;  4KHA A;  5KCV A;  5C5B A;  1V5M A;  3DXD A;  2J59 M;  3TFM A;  4A6F B;  3OAN A;  3FEH A;  1I7A A;  1I2H A;  2DX1 A;  2CRF A;  3G9W A;  1U29 A;  3ODX A;  4A5K A;  3QIJ A;  2ELA A;  5DI9 B;  3ODW A;  5CLL B;  3V5W A;  3SO6 A;  4GZU A;  1OY2 A;  5JP4 A;  2OTX A;  3HW2 B;  2YF0 A;  3MPX A;  2DFK A;  3T06 A;  4ZRK A;  5J3T A;  1WJM A;  4IOY X;  2E2X A;  3ZDT A;  3IVF A;  2BCJ A;  3X23 A;  1TXD A;  2DTC A;  4A6F A;  2RGN B;  4HB2 B;  2GJY A;  4ZRI A;  4ZRJ A;  3ULB A;  5L81 A;  1FHO A;  2UZR A;  2D9X A;  5C16 A;  2AEH A;  1WJ1 A;  5D3W A;  2D10 A;  1UNP A;  2MFQ A;  1Y5O A;  3A8Q A;  1EGX A;  1V88 A;  2MKR A;  1FGZ A;  3KZ1 A;  1ZSQ A;  4IAP A;  1MKE A;  1UNQ A;  1EF1 A;  2VKI A;  4F7G A;  1H4R A;  1ZC3 B;  4KAX B;  4CYE A;  3KY9 A;  4TKN A;  1K5G B;  3P7Z A;  2XQN M;  1J19 A;  2J0J A;  4H8S A;  1EVH A;  1M7R A;  2DKP A;  4YON A;  1FAO A;  1U5E A;  1V61 A;  2GCL A;  1RRP B;  1SHC A;  2Y8F A;  3ZVR A;  2EMS A;  4F7U P;  2DKQ A;  1OMW A;  1Z87 A;  4A6K A;  2COC A;  4A6H A;  4WSF A;  2RVB B;  4GN1 A;  5KQ4 A;  2DHJ A;  2UZS A;  3BJI A;  3AU4 A;  4K2P A;  2ROV A;  2I5F A;  5HE2 A;  2N0Y A;  2YS3 A;  1X05 A;  2R09 A;  3PG7 A;  2YVC A;  1QQG A;  3PEG A;  1X1G A;  2COA A;  5C6R A;  2J0K A;  2Y8G A;  4D0N B;  4KHB B;  2DHI A;  2VRW B;  4Y94 A;  2H7E A;  2D2Q A;  1MIX A;  1E5W A;  2ROZ B;  1UPR A;  4HB0 B;  5JLJ B;  1MK9 B;  2Y7B A;  5CLQ B;  2LOZ A;  5HE0 A;  1H10 A;  3FSS A;  2RUK B;  2DN6 A;  3GYP A;  1XR0 B;  4DBB A;  2D9Z A;  1N3H A;  3CIK A;  1NU2 A; 
#chains in the Genus database with same CATH topology
 2V76 A;  3ML4 A;  1P6S A;  2QKL A;  3QBV B;  2JP2 A;  2KGX B;  2P0D A;  3FM8 C;  1FB8 A;  2LYD A;  5I2M A;  1PFJ A;  1FGY A;  4WVF B;  1W1D A;  1ZVR A;  1XX0 A;  2GS0 A;  1WGU A;  4OT1 A;  2VSZ A;  3AU5 A;  5D27 A;  2NMB A;  1MI1 A;  2D9V A;  5D3X A;  2X18 A;  1WG7 A;  2M14 A;  3TO1 A;  5KQ1 A;  5LON B;  4TYZ A;  2DYQ A;  2Z13 A;  2RLO A;  2AL6 A;  1UNR A;  4K2O A;  3A98 B;  2W2W A;  1U5F A;  1FOE A;  1TJ6 A;  3TVV A;  1LB1 A;  2Z0P A;  2Z0Q A;  1V89 A;  3DXC A;  4Z2M B;  2COF A;  4EKU A;  3AJ4 A;  4CHM A;  4CHJ A;  3KSY A;  3KRW A;  1PLS A;  2RRF A;  2ELB A;  3MDB C;  1IRS A;  1UPQ A;  3D8E A;  2ZKM X;  2I1K A;  3VIA A;  2COD A;  1MAI A;  1V5P A;  5J3Y A;  4P7I A;  3PVU A;  5DHF B;  3HQC A;  4DIX A;  5DHA B;  4NY0 A;  4DX9 0;  4PQ0 A;  2DLW A;  1DBH A;  1U2B A;  4XWX A;  2KR0 A;  3D8D A;  5C79 A;  4GMV A;  1BTK A;  4HB4 B;  4YL8 A;  2RSG A;  1X86 A;  1B55 A;  2CAY A;  4MT7 A;  3P6A A;  2DYN A;  2IYB A;  5LOP B;  2H7D A;  3SV1 A;  3O96 A;  2D9Y A;  4QJ5 B;  2J0M A;  2GUM A;  2R0D A;  4C0A A;  1AQC A;  3QWM A;  1KZG A;  2L2I A;  5FI0 A;  3TCA A;  1NTY A;  1X1F A;  1ZM0 A;  3VOQ A;  2K2U A;  2K2J A;  1XKE A;  2Q13 A;  4GPT B;  2EC1 A;  2Z59 A;  3PP2 A;  5JHG A;  1KI1 B;  1KZ7 A;  2D4Q A;  3PVL A;  4HDO A;  2LUL A;  3OHM B;  3NWD A;  4DXA B;  1GG3 A;  4WJ7 A;  1AWE A;  3F0W A;  5J3Q A;  2LKO A;  5FI1 A;  1U5D A;  2ZPY A;  2I5C A;  4HDQ A;  3RCP A;  2KIE A;  5JHH A;  2D11 A;  2EJ8 A;  2M38 A;  1TQZ A;  2YS1 A;  4DX8 A;  2YS5 A;  2L1C A;  4GNK B;  2DA0 A;  2ADZ A;  4MK0 A;  2CY5 A;  1WI1 A;  4Z2N A;  4B6H A;  3NWA A;  1DDV A;  3GYO A;  2LOX A;  2RNR B;  1EAZ A;  1WVH A;  2K00 A;  4OSN A;  1W1G A;  2LG1 A;  3ODO A;  3U7D A;  2KUP A;  3HK0 A;  5D3Y A;  2KUQ A;  2D9W A;  2NZ8 B;  5DIF B;  1FHW A;  4EJN A;  1V5U A;  1Q67 A;  2P8V A;  2Z0O A;  2CY4 A;  1BTN A;  2YT0 A;  3SYX A;  4L1R A;  1MK7 B;  3A8P A;  4KVG B;  4PNK A;  1OQN A;  1XOD A;  5HE1 A;  1XCG A;  1P5T A;  4EMO A;  2HTH B;  2Z14 A;  1BAK A;  3PVW A;  4HAY B;  3WYF B;  3ULC A;  1WGQ A;  1X11 A;  4BBK A;  3KRX A;  1NTV A;  2UVM A;  4GXB A;  3UZT A;  2YT2 A;  2YRY A;  5DH9 B;  1QC6 A;  4GMX B;  3HSA A;  5HE3 A;  1UEF A;  3F5R A;  3PZD A;  3CXB B;  1DRO A;  2I1J A;  1P3R A;  4HAX B;  4HAV B;  3N7C A;  1ZC4 B;  2YT1 A;  1U27 A;  2K8E A;  2G35 A;  2W2X D;  2MWN B;  1W1H A;  2DX5 A;  1PMS A;  5M4Y B;  2DHK A;  1GC6 A;  2N23 A;  2IFS A;  5GOW B;  1DDM A;  3PSC A;  1LW3 A;  4QJ4 B;  1DDW A;  1Y19 B;  3WA0 A;  3LJU X;  4HHV A;  1MPH A;  4QJ3 B;  1NI2 A;  4K81 A;  2P0F A;  1ISN A;  4NSW A;  4IFS A;  2OQB A;  3BIN A;  4HAZ B;  4D6W A;  4HAW B;  2YSZ A;  2W2X C;  3U8Z A;  2FJL A;  1J0W A;  1XD4 A;  4HAU B;  2PZ1 A;  2QKM A;  2P0H A;  1FHX A;  3M1I B;  5EFX A;  4F7H A;  5C5B B;  1MIZ B;  2GCJ A;  1K5D B;  4KHO A;  1DYN A;  3NSU A;  4MY6 A;  1M7E A;  4K17 A;  2HE7 A;  5D3V A;  2MDX A;  3SNH A;  4HAT B;  3TW1 A;  3D8F A;  1SGH A;  1BWN A;  1RJ2 A;  3SUZ A;  2KCJ A;  1GC7 A;  1ZYI A;  1U5G A;  4HB3 B;  3DXE A;  4L6E A;  2EMT A;  4KHA A;  5KCV A;  5C5B A;  1V5M A;  3DXD A;  2J59 M;  3TFM A;  3B77 A;  3OAN A;  4A6F B;  3FEH A;  1I7A A;  1I2H A;  2DX1 A;  2CRF A;  3G9W A;  1U29 A;  3ODX A;  4A5K A;  3HIE A;  3QIJ A;  2ELA A;  5DI9 B;  3ODW A;  5CLL B;  3V5W A;  3SO6 A;  4GZU A;  1OY2 A;  5JP4 A;  2OTX A;  3HW2 B;  2YF0 A;  3MPX A;  2DFK A;  3T06 A;  4ZRK A;  5J3T A;  1WJM A;  4IOY X;  2E2X A;  3ZDT A;  3IVF A;  2BCJ A;  3X23 A;  1TXD A;  2DTC A;  4A6F A;  2RGN B;  4HB2 B;  2GJY A;  4ZRI A;  4ZRJ A;  3ULB A;  5L81 A;  1FHO A;  2KIG A;  2UZR A;  2D9X A;  3DCX A;  5C16 A;  2AEH A;  1WJ1 A;  5D3W A;  2D10 A;  1UNP A;  2MFQ A;  1Y5O A;  3A8Q A;  1EGX A;  1V88 A;  2MKR A;  1FGZ A;  3KZ1 A;  1ZSQ A;  4IAP A;  1MKE A;  1UNQ A;  1EF1 A;  2VKI A;  4F7G A;  1H4R A;  1ZC3 B;  4QXA B;  4KAX B;  4CYE A;  3KY9 A;  4TKN A;  1K5G B;  3P7Z A;  2XQN M;  1J19 A;  2J0J A;  4H8S A;  1EVH A;  1M7R A;  2DKP A;  4YON A;  1FAO A;  1U5E A;  1V61 A;  2GCL A;  1RRP B;  1SHC A;  2Y8F A;  3ZVR A;  2EMS A;  4F7U P;  2DKQ A;  1OMW A;  3FVC A;  1Z87 A;  4A6K A;  2COC A;  4A6H A;  4WSF A;  2RVB B;  4GN1 A;  5KQ4 A;  2DHJ A;  2R2Y A;  2UZS A;  3BJI A;  3AU4 A;  4K2P A;  2ROV A;  2I5F A;  5HE2 A;  2N0Y A;  2YS3 A;  1X05 A;  2R09 A;  4HSI A;  3PG7 A;  2YVC A;  1QQG A;  3PEG A;  1X1G A;  2COA A;  2FJU B;  5C6R A;  4GOU A;  2Z4D A;  2J0K A;  2Y8G A;  4D0N B;  3NWF A;  4KHB B;  4CSQ A;  1T77 A;  2DHI A;  2VRW B;  5IRS A;  4Y94 A;  2H7E A;  2D2Q A;  1MIX A;  5LG4 B;  1E5W A;  2ROZ B;  1UPR A;  4HB0 B;  5I2S A;  5JLJ B;  1MK9 B;  2Y7B A;  5CLQ B;  2LOZ A;  5HE0 A;  1H10 A;  3U12 A;  3A58 A;  3FSS A;  2RUK B;  2DN6 A;  2NBV A;  3GYP A;  1XR0 B;  4DBB A;  2D9Z A;  3NW8 A;  2K49 A;  1N3H A;  3CIK A;  4KHB A;  1NU2 A; 
#chains in the Genus database with same CATH homology
 2V76 A;  3ML4 A;  1P6S A;  2QKL A;  3QBV B;  2JP2 A;  2KGX B;  2P0D A;  3FM8 C;  1FB8 A;  2LYD A;  1PFJ A;  1FGY A;  4WVF B;  1W1D A;  1ZVR A;  1XX0 A;  2GS0 A;  1WGU A;  2VSZ A;  3AU5 A;  5D27 A;  2NMB A;  2D9V A;  5D3X A;  2X18 A;  1WG7 A;  2M14 A;  3TO1 A;  5KQ1 A;  5LON B;  4TYZ A;  2DYQ A;  2RLO A;  2AL6 A;  1UNR A;  4K2O A;  3A98 B;  2W2W A;  1U5F A;  1FOE A;  1TJ6 A;  3TVV A;  1LB1 A;  2Z0P A;  2Z0Q A;  1V89 A;  3DXC A;  4Z2M B;  2COF A;  4EKU A;  3AJ4 A;  4CHM A;  4CHJ A;  3KSY A;  3KRW A;  1PLS A;  2ELB A;  3MDB C;  1IRS A;  1UPQ A;  3D8E A;  2I1K A;  3VIA A;  2COD A;  1MAI A;  1V5P A;  5J3Y A;  4P7I A;  3PVU A;  5DHF B;  3HQC A;  5DHA B;  4NY0 A;  4DX9 0;  4PQ0 A;  2DLW A;  1DBH A;  1U2B A;  4XWX A;  3D8D A;  5C79 A;  4GMV A;  1BTK A;  4HB4 B;  4YL8 A;  2RSG A;  1X86 A;  1B55 A;  2CAY A;  4MT7 A;  3P6A A;  2DYN A;  2IYB A;  5LOP B;  2H7D A;  3SV1 A;  3O96 A;  2D9Y A;  2J0M A;  2R0D A;  4C0A A;  1AQC A;  3QWM A;  1KZG A;  2L2I A;  5FI0 A;  3TCA A;  1NTY A;  1X1F A;  1ZM0 A;  3VOQ A;  2K2U A;  2K2J A;  1XKE A;  2Q13 A;  4GPT B;  2EC1 A;  3PP2 A;  5JHG A;  1KI1 B;  1KZ7 A;  2D4Q A;  3PVL A;  4HDO A;  2LUL A;  4DXA B;  1GG3 A;  4WJ7 A;  1AWE A;  3F0W A;  5J3Q A;  2LKO A;  5FI1 A;  1U5D A;  2ZPY A;  2I5C A;  4HDQ A;  3RCP A;  5JHH A;  2D11 A;  2EJ8 A;  2M38 A;  1TQZ A;  2YS1 A;  4DX8 A;  2YS5 A;  2L1C A;  2DA0 A;  2ADZ A;  4MK0 A;  2CY5 A;  1WI1 A;  4Z2N A;  4B6H A;  1DDV A;  3GYO A;  2LOX A;  2RNR B;  1EAZ A;  1WVH A;  2K00 A;  1W1G A;  2LG1 A;  3ODO A;  3U7D A;  2KUP A;  3HK0 A;  5D3Y A;  2D9W A;  2NZ8 B;  5DIF B;  1FHW A;  4EJN A;  1V5U A;  1Q67 A;  2P8V A;  2Z0O A;  2CY4 A;  1BTN A;  2YT0 A;  3SYX A;  1MK7 B;  3A8P A;  4KVG B;  4PNK A;  1OQN A;  1XOD A;  5HE1 A;  1XCG A;  1P5T A;  4EMO A;  2HTH B;  1BAK A;  3PVW A;  4HAY B;  3WYF B;  3ULC A;  1WGQ A;  1X11 A;  4BBK A;  3KRX A;  1NTV A;  2UVM A;  4GXB A;  3UZT A;  2YRY A;  5DH9 B;  1QC6 A;  4GMX B;  5HE3 A;  1UEF A;  3F5R A;  3PZD A;  3CXB B;  1DRO A;  2I1J A;  1P3R A;  4HAX B;  4HAV B;  3N7C A;  1ZC4 B;  2YT1 A;  1U27 A;  2G35 A;  2W2X D;  2MWN B;  1W1H A;  2DX5 A;  1PMS A;  2DHK A;  1GC6 A;  2N23 A;  2IFS A;  5GOW B;  1DDM A;  3PSC A;  1LW3 A;  1DDW A;  1Y19 B;  3WA0 A;  3LJU X;  4HHV A;  1MPH A;  1NI2 A;  4K81 A;  2P0F A;  1ISN A;  4NSW A;  4IFS A;  2OQB A;  3BIN A;  4HAZ B;  4HAW B;  2YSZ A;  2W2X C;  3U8Z A;  2FJL A;  1J0W A;  1XD4 A;  4HAU B;  2PZ1 A;  2QKM A;  2P0H A;  1FHX A;  3M1I B;  5EFX A;  4F7H A;  5C5B B;  1MIZ B;  2GCJ A;  1K5D B;  4KHO A;  1DYN A;  3NSU A;  4MY6 A;  1M7E A;  4K17 A;  2HE7 A;  5D3V A;  2MDX A;  3SNH A;  4HAT B;  3TW1 A;  3D8F A;  1SGH A;  1BWN A;  1RJ2 A;  3SUZ A;  2KCJ A;  1GC7 A;  1U5G A;  4HB3 B;  3DXE A;  4L6E A;  2EMT A;  4KHA A;  5KCV A;  5C5B A;  1V5M A;  3DXD A;  2J59 M;  3TFM A;  4A6F B;  3OAN A;  3FEH A;  1I7A A;  1I2H A;  2DX1 A;  2CRF A;  3G9W A;  1U29 A;  3ODX A;  4A5K A;  3QIJ A;  2ELA A;  5DI9 B;  3ODW A;  5CLL B;  3V5W A;  3SO6 A;  4GZU A;  1OY2 A;  5JP4 A;  2OTX A;  3HW2 B;  2YF0 A;  3MPX A;  2DFK A;  3T06 A;  4ZRK A;  5J3T A;  1WJM A;  4IOY X;  2E2X A;  3ZDT A;  3IVF A;  2BCJ A;  3X23 A;  1TXD A;  2DTC A;  4A6F A;  2RGN B;  4HB2 B;  2GJY A;  4ZRI A;  4ZRJ A;  3ULB A;  5L81 A;  1FHO A;  2UZR A;  2D9X A;  5C16 A;  2AEH A;  1WJ1 A;  5D3W A;  2D10 A;  1UNP A;  2MFQ A;  1Y5O A;  3A8Q A;  1EGX A;  1V88 A;  2MKR A;  1FGZ A;  3KZ1 A;  1ZSQ A;  4IAP A;  1MKE A;  1UNQ A;  1EF1 A;  2VKI A;  4F7G A;  1H4R A;  1ZC3 B;  4KAX B;  4CYE A;  3KY9 A;  4TKN A;  1K5G B;  3P7Z A;  2XQN M;  1J19 A;  2J0J A;  4H8S A;  1EVH A;  1M7R A;  2DKP A;  4YON A;  1FAO A;  1U5E A;  1V61 A;  2GCL A;  1RRP B;  1SHC A;  2Y8F A;  3ZVR A;  2EMS A;  4F7U P;  2DKQ A;  1OMW A;  1Z87 A;  4A6K A;  2COC A;  4A6H A;  4WSF A;  2RVB B;  4GN1 A;  5KQ4 A;  2DHJ A;  2UZS A;  3BJI A;  3AU4 A;  4K2P A;  2ROV A;  2I5F A;  5HE2 A;  2N0Y A;  2YS3 A;  1X05 A;  2R09 A;  3PG7 A;  2YVC A;  1QQG A;  3PEG A;  1X1G A;  2COA A;  5C6R A;  2J0K A;  2Y8G A;  4D0N B;  4KHB B;  2DHI A;  2VRW B;  4Y94 A;  2H7E A;  2D2Q A;  1MIX A;  1E5W A;  2ROZ B;  1UPR A;  4HB0 B;  5JLJ B;  1MK9 B;  2Y7B A;  5CLQ B;  2LOZ A;  5HE0 A;  1H10 A;  3FSS A;  2RUK B;  2DN6 A;  3GYP A;  1XR0 B;  4DBB A;  2D9Z A;  1N3H A;  3CIK A;  1NU2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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