1AWEA

Human sos1 pleckstrin homology (ph) domain, nmr, 20 structures
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
130
structure length
130
Chain Sequence
MNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains.
pubmed doi rcsb
molecule tags Signal transduction
source organism Homo sapiens
molecule keywords SOS1
total genus 17
structure length 130
sequence length 130
ec nomenclature
pdb deposition date 1997-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1aweA00
4HAWB 5HE3A 1J0WA 4A6FA 2IFSA 2KUPA 1KZGA 3NSUA 4B6HA 3O96A 2LKOA 5DHFB 5C16A 1GG3A 3D8FA 2LOXA 5JP4A 3KZ1A 4HB2B 1XR0B 2ELBA 4NY0A 3MPXA 3G9WA 4HDOA 5CLLB 4YONA 3KY9A 3TO1A 4MK0A 2P8VA 2YSZA 1OMWA 2LYDA 1AWEA 1WG7A 2DA0A 2ROVA 4WVFB 1ZVRA 2K2UA 4F7HA 2CAYA 1NI2A 1EF1A 2MWNB 5JHHA 2Y8FA 2N0YA 3PP2A 4HB3B 1W1DA 1N3HA 2D9YA 5KQ1A 2MDXA 1PMSA 4HATB 2RNRB 5C6RA 4CHMA 2CODA 2CY5A 2I5FA 2D9WA 2DN6A 1MK7B 4PQ0A 3PVLA 3DXCA 4TKNA 2RUKB 1M7RA 1TQZA 2DHIA 2KCJA 5GOWB 3F5RA 3LJUX 4GN1A 1XX0A 2N23A 2D2QA 4EJNA 3VIAA 4HAVB 1FOEA 4EKUA 3QIJA 2IYBA 4HDQA 1FB8A 4K17A 1Y5OA 4P7IA 1FHWA 1H10A 1I2HA 2M38A 1XCGA 5KQ4A 2JP2A 1DYNA 3P6AA 1XODA 5JHGA 1QC6A 2D4QA 3WYFB 2YT1A 5KCVA 1Z87A 4H8SA 1XD4A 4HHVA 4KAXB 2GS0A 3HK0A 2DYQA 2LULA 3V5WA 4C0AA 4HB0B 4NSWA 3F0WA 1X1GA 4MT7A 4F7GA 3AU4A 2W2WA 1B55A 5C5BB 2DHJA 1NTYA 4GZUA 4KHBB 2FJLA 5LONB 1UPRA 3ULBA 2I1KA 4EMOA 3PVUA 2GCJA 3U8ZA 3TFMA 1V5PA 5D3XA 2G35A 1AQCA 1ISNA 2CY4A 2OQBA 2HE7A 5J3QA 5LOPB 5C79A 2YF0A 5J3YA 3WA0A 2W2XD 2K00A 4DBBA 5D3YA 4Y94A 3HW2B 1P3RA 4CYEA 2D10A 3P7ZA 2KGXB 1RJ2A 3X23A 1BTKA 1UNRA 3KRXA 1V5UA 3ODOA 3QWMA 1EAZA 4GMXB 2NZ8B 2VSZA 4KHAA 2M14A 2J0MA 3BINA 1KI1B 2D11A 2DTCA 2ELAA 2P0HA 2QKMA 3AJ4A 4MY6A 1E5WA 3TW1A 3A8QA 2Z0QA 2DX5A 4K2PA 2NMBA 1RRPB 3PG7A 2H7EA 5DHAB 1KZ7A 1WJMA 2DLWA 2P0FA 1K5DB 3SV1A 3SYXA 1WVHA 4HAZB 4D0NB 1UNQA 4KVGB 2MKRA 2GCLA 2J0JA 2EMSA 4IOYX 5HE0A 3U7DA 1Y19B 3DXEA 2J59M 1MK9B 1NU2A 3SO6A 3FM8C 1V88A 5C5BA 1X1FA 2XQNM 2QKLA 4L6EA 5D3WA 3SUZA 2BCJA 3FSSA 4A6KA 1PLSA 1WI1A 3FEHA 1XKEA 5D27A 4ZRJA 2UZSA 2YVCA 1FGYA 3PVWA 2W2XC 1EGXA 3A8PA 3ODXA 1J19A 1DDVA 1WGUA 5FI0A 1LW3A 2COFA 4DXAB 1X05A 2YS1A 1GC7A 1U5GA 1UEFA 2V76A 1QQGA 2ROZB 1DROA 2R09A 3RCPA 2YS5A 3ML4A 4Z2MB 3PSCA 4CHJA 5D3VA 2ZPYA 2H7DA 1V5MA 4IFSA 4GXBA 2L2IA 2D9VA 2RLOA 4HAYB 1MAIA 4A5KA 2DKQA 3SNHA 1SHCA 1W1GA 3D8DA 4IAPA 4GPTB 1DDWA 1MPHA 3GYOA 3ZDTA 4HAXB 2UVMA 2DKPA 3BJIA 4ZRIA 1U29A 2R0DA 4WSFA 1TJ6A 4BBKA 5DI9B 4A6HA 1NTVA 2Z0OA 4XWXA 3IVFA 3D8EA 3OANA 2P0DA 1DDMA 1PFJA 3M1IB 3GYPA 4GMVA 1UPQA 1U2BA 3QBVB 5L81A 1ZSQA 4YL8A 3UZTA 2DFKA 5JLJB 1Q67A 5DH9B 2LG1A 3ODWA 3AU5A 4K2OA 2Q13A 4PNKA 2LOZA 2D9ZA 3VOQA 2COAA 2AEHA 5HE1A 3CXBB 1ZC3B 3ULCA 4KHOA 2YS3A 3HQCA 4K81A 4DX90 2ADZA 4WJ7A 2CRFA 2K2JA 2EJ8A 2E2XA 4TYZA 1H4RA 1FHOA 1FGZA 4HB4B 2J0KA 1MKEA 1K5GB 4A6FB 5FI1A 1U5FA 2DX1A 2AL6A 2D9XA 2GJYA 1BWNA 1UNPA 3ZVRA 5J3TA 2X18A 1I7AA 2PZ1A 3N7CA 2MFQA 2RSGA 3A98B 1P5TA 5DIFB 1P6SA 2RVBB 1W1HA 2Y8GA 4DX8A 1U5DA 3PZDA 4F7UP 1BTNA 3DXDA 3TVVA 1WJ1A 3TCAA 1V61A 1LB1A 2DHKA 5HE2A 2I1JA 1U27A 2VKIA 1DBHA 3T06A 2YRYA 1X11A 3MDBC 1MIZB 2HTHB 2COCA 1FHXA 3KRWA 5CLQB 2Y7BA 1TXDA 2L1CA 1WGQA 4Z2NA 4ZRKA 1IRSA 1X86A 1FAOA 5EFXA 1ZC4B 2UZRA 2DYNA 1BAKA 2EC1A 3CIKA 1M7EA 3PEGA 1U5EA 2I5CA 4HAUB 1V89A 1MIXA 2OTXA 1SGHA 2YT0A 2VRWB 1GC6A 1EVHA 1OQNA 1OY2A 2EMTA 3KSYA 2RGNB 1ZM0A 2Z0PA
chains in the Genus database with same CATH superfamily
4HAWB 5HE3A 1J0WA 4A6FA 2IFSA 2KUPA 4GOUA 1KZGA 3NSUA 4GNKB 4B6HA 3O96A 2LKOA 5DHFB 5C16A 1GG3A 3D8FA 2LOXA 5I2MA 5JP4A 3KZ1A 4HB2B 1XR0B 2ELBA 4NY0A 3MPXA 3NWDA 3G9WA 4HDOA 5CLLB 4YONA 3KY9A 3TO1A 2KUQA 4MK0A 4OSNA 2P8VA 2YSZA 1OMWA 2LYDA 1AWEA 1WG7A 2DA0A 2ROVA 4WVFB 1ZVRA 2K2UA 4F7HA 2CAYA 1NI2A 1EF1A 2MWNB 5JHHA 2Y8FA 2N0YA 3PP2A 4HB3B 1W1DA 1N3HA 2D9YA 5KQ1A 2MDXA 1PMSA 4HATB 3NW8A 2RNRB 3OHMB 5C6RA 4CHMA 2CODA 2CY5A 2I5FA 1T77A 2D9WA 2Z14A 2DN6A 1MK7B 4PQ0A 3PVLA 3DXCA 4TKNA 2RUKB 1M7RA 1TQZA 2DHIA 2KCJA 5GOWB 3F5RA 3LJUX 4GN1A 1XX0A 2N23A 2D2QA 4EJNA 3FVCA 3VIAA 4HAVB 1FOEA 4EKUA 5IRSA 3QIJA 2IYBA 4HDQA 1FB8A 4K17A 1Y5OA 4P7IA 1FHWA 1H10A 4HSIA 2Z59A 1I2HA 2M38A 1XCGA 5KQ4A 2JP2A 1DYNA 3P6AA 1XODA 5JHGA 1QC6A 2D4QA 3WYFB 2YT1A 5KCVA 1Z87A 4H8SA 1XD4A 4HHVA 4KAXB 2GS0A 3HK0A 2DYQA 2LULA 3V5WA 2Z4DA 4C0AA 4HB0B 4NSWA 3F0WA 1X1GA 4MT7A 4F7GA 3AU4A 2W2WA 1B55A 5C5BB 2DHJA 1NTYA 4GZUA 4KHBB 2FJLA 5LONB 4CSQA 1UPRA 3ULBA 2NBVA 2I1KA 4EMOA 3PVUA 2GCJA 3U8ZA 3TFMA 1V5PA 5D3XA 2G35A 1AQCA 1ISNA 2CY4A 2OQBA 3HSAA 2HE7A 5J3QA 5LOPB 5C79A 2YF0A 5J3YA 4L1RA 3WA0A 2W2XD 2K00A 4DBBA 5D3YA 4Y94A 3HW2B 1P3RA 4CYEA 4QXAB 2D10A 3P7ZA 2KGXB 1RJ2A 3X23A 1BTKA 1UNRA 3KRXA 1V5UA 3ODOA 2FJUB 1EAZA 3QWMA 4GMXB 2NZ8B 2VSZA 4KHAA 2M14A 2J0MA 2P0HA 3BINA 1KI1B 2D11A 2DTCA 2ELAA 2QKMA 3AJ4A 4MY6A 1E5WA 4QJ3B 3TW1A 3A8QA 2K49A 2Z0QA 2KIGA 2DX5A 4QJ4B 4K2PA 2NMBA 1RRPB 3PG7A 2H7EA 3B77A 5DHAB 1KZ7A 1WJMA 2DLWA 2P0FA 1K5DB 3SV1A 3SYXA 1WVHA 4HAZB 4D0NB 1UNQA 4KVGB 2MKRA 2GCLA 2J0JA 2EMSA 4IOYX 5HE0A 3U7DA 1Y19B 3DXEA 2J59M 4OT1A 1MK9B 1NU2A 3SO6A 3FM8C 1V88A 5C5BA 1X1FA 2XQNM 2QKLA 2R2YA 4L6EA 5D3WA 3SUZA 4KHBA 2BCJA 3FSSA 4A6KA 1PLSA 1WI1A 3FEHA 1XKEA 5D27A 4ZRJA 2UZSA 2YVCA 1FGYA 3PVWA 2Z13A 2W2XC 1EGXA 3A8PA 3ODXA 1J19A 1DDVA 1WGUA 5FI0A 1LW3A 2COFA 4DXAB 1X05A 2YS1A 3NWAA 1GC7A 1U5GA 1UEFA 2V76A 1QQGA 2ROZB 5M4YB 1DROA 2R09A 3RCPA 2YS5A 2KIEA 3ML4A 4Z2MB 3PSCA 4CHJA 5D3VA 2ZPYA 2H7DA 1V5MA 4IFSA 4GXBA 2L2IA 2D9VA 2RLOA 4HAYB 1ZYIA 1MAIA 4A5KA 2DKQA 3SNHA 1SHCA 1W1GA 3D8DA 4IAPA 4GPTB 1DDWA 2KR0A 1MPHA 3GYOA 5I2SA 3ZDTA 4HAXB 2UVMA 2DKPA 3BJIA 4ZRIA 1U29A 2R0DA 4WSFA 1TJ6A 4BBKA 5DI9B 4A6HA 1NTVA 2Z0OA 4XWXA 3IVFA 3D8EA 3OANA 2P0DA 1DDMA 3A58A 1PFJA 3M1IB 3GYPA 4GMVA 1UPQA 1U2BA 3QBVB 5L81A 1ZSQA 4YL8A 3UZTA 2DFKA 5JLJB 1Q67A 3U12A 5DH9B 2LG1A 3ODWA 3AU5A 4K2OA 2Q13A 4PNKA 5LG4B 2LOZA 2D9ZA 3NWFA 3VOQA 2COAA 2AEHA 5HE1A 3CXBB 1ZC3B 3ULCA 4KHOA 2YS3A 3HQCA 4K81A 4DX90 2ADZA 4D6WA 4WJ7A 2CRFA 2K2JA 2EJ8A 2E2XA 2ZKMX 4TYZA 1H4RA 1FHOA 1FGZA 4HB4B 2J0KA 1MKEA 1K5GB 4A6FB 3DCXA 5FI1A 1U5FA 2GUMA 2DX1A 2K8EA 2AL6A 2D9XA 2GJYA 1BWNA 1UNPA 3ZVRA 5J3TA 2X18A 1I7AA 2PZ1A 3N7CA 2MFQA 2RSGA 3A98B 2YT2A 1P5TA 5DIFB 1P6SA 2RVBB 2RRFA 1W1HA 2Y8GA 3HIEA 4DX8A 1U5DA 3PZDA 4F7UP 1BTNA 3DXDA 3TVVA 1WJ1A 3TCAA 1MI1A 1V61A 1LB1A 2DHKA 5HE2A 2I1JA 1U27A 2VKIA 1DBHA 3T06A 2YRYA 1X11A 3MDBC 1MIZB 2HTHB 2COCA 1FHXA 3KRWA 5CLQB 2Y7BA 1TXDA 2L1CA 1WGQA 4Z2NA 4ZRKA 1IRSA 1X86A 1FAOA 5EFXA 1ZC4B 4QJ5B 2UZRA 2DYNA 1BAKA 2EC1A 3CIKA 1M7EA 3PEGA 1U5EA 2I5CA 4HAUB 1V89A 1MIXA 2OTXA 1SGHA 2YT0A 2VRWB 1GC6A 1EVHA 1OQNA 4DIXA 1OY2A 2EMTA 3KSYA 2RGNB 1ZM0A 2Z0PA
chains in the Genus database with same CATH topology
4HAWB 5HE3A 1J0WA 4A6FA 2IFSA 2KUPA 1KZGA 3NSUA 4B6HA 3O96A 2LKOA 5DHFB 5C16A 1GG3A 3D8FA 2LOXA 5JP4A 3KZ1A 4HB2B 1XR0B 2ELBA 4NY0A 3MPXA 3G9WA 4HDOA 5CLLB 4YONA 3KY9A 3TO1A 4MK0A 2P8VA 2YSZA 1OMWA 2LYDA 1AWEA 1WG7A 2DA0A 2ROVA 4WVFB 1ZVRA 2K2UA 4F7HA 2CAYA 1NI2A 1EF1A 2MWNB 5JHHA 2Y8FA 2N0YA 3PP2A 4HB3B 1W1DA 1N3HA 2D9YA 5KQ1A 2MDXA 1PMSA 4HATB 2RNRB 5C6RA 4CHMA 2CODA 2CY5A 2I5FA 2D9WA 2DN6A 1MK7B 4PQ0A 3PVLA 3DXCA 4TKNA 2RUKB 1M7RA 1TQZA 2DHIA 2KCJA 5GOWB 3F5RA 3LJUX 4GN1A 1XX0A 2N23A 2D2QA 4EJNA 3VIAA 4HAVB 1FOEA 4EKUA 3QIJA 2IYBA 4HDQA 1FB8A 4K17A 1Y5OA 4P7IA 1FHWA 1H10A 1I2HA 2M38A 1XCGA 5KQ4A 2JP2A 1DYNA 3P6AA 1XODA 5JHGA 1QC6A 2D4QA 3WYFB 2YT1A 5KCVA 1Z87A 4H8SA 1XD4A 4HHVA 4KAXB 2GS0A 3HK0A 2DYQA 2LULA 3V5WA 4C0AA 4HB0B 4NSWA 3F0WA 1X1GA 4MT7A 4F7GA 3AU4A 2W2WA 1B55A 5C5BB 2DHJA 1NTYA 4GZUA 4KHBB 2FJLA 5LONB 1UPRA 3ULBA 2I1KA 4EMOA 3PVUA 2GCJA 3U8ZA 3TFMA 1V5PA 5D3XA 2G35A 1AQCA 1ISNA 2CY4A 2OQBA 2HE7A 5J3QA 5LOPB 5C79A 2YF0A 5J3YA 3WA0A 2W2XD 2K00A 4DBBA 5D3YA 4Y94A 3HW2B 1P3RA 4CYEA 2D10A 3P7ZA 2KGXB 1RJ2A 3X23A 1BTKA 1UNRA 3KRXA 1V5UA 3ODOA 3QWMA 1EAZA 4GMXB 2NZ8B 2VSZA 4KHAA 2M14A 2J0MA 3BINA 1KI1B 2D11A 2DTCA 2ELAA 2P0HA 2QKMA 3AJ4A 4MY6A 1E5WA 3TW1A 3A8QA 2Z0QA 2DX5A 4K2PA 2NMBA 1RRPB 3PG7A 2H7EA 5DHAB 1KZ7A 1WJMA 2DLWA 2P0FA 1K5DB 3SV1A 3SYXA 1WVHA 4HAZB 4D0NB 1UNQA 4KVGB 2MKRA 2GCLA 2J0JA 2EMSA 4IOYX 5HE0A 3U7DA 1Y19B 3DXEA 2J59M 1MK9B 1NU2A 3SO6A 3FM8C 1V88A 5C5BA 1X1FA 2XQNM 2QKLA 4L6EA 5D3WA 3SUZA 2BCJA 3FSSA 4A6KA 1PLSA 1WI1A 3FEHA 1XKEA 5D27A 4ZRJA 2UZSA 2YVCA 1FGYA 3PVWA 2W2XC 1EGXA 3A8PA 3ODXA 1J19A 1DDVA 1WGUA 5FI0A 1LW3A 2COFA 4DXAB 1X05A 2YS1A 1GC7A 1U5GA 1UEFA 2V76A 1QQGA 2ROZB 1DROA 2R09A 3RCPA 2YS5A 3ML4A 4Z2MB 3PSCA 4CHJA 5D3VA 2ZPYA 2H7DA 1V5MA 4IFSA 4GXBA 2L2IA 2D9VA 2RLOA 4HAYB 1MAIA 4A5KA 2DKQA 3SNHA 1SHCA 1W1GA 3D8DA 4IAPA 4GPTB 1DDWA 1MPHA 3GYOA 3ZDTA 4HAXB 2UVMA 2DKPA 3BJIA 4ZRIA 1U29A 2R0DA 4WSFA 1TJ6A 4BBKA 5DI9B 4A6HA 1NTVA 2Z0OA 4XWXA 3IVFA 3D8EA 3OANA 2P0DA 1DDMA 1PFJA 3M1IB 3GYPA 4GMVA 1UPQA 1U2BA 3QBVB 5L81A 1ZSQA 4YL8A 3UZTA 2DFKA 5JLJB 1Q67A 5DH9B 2LG1A 3ODWA 3AU5A 4K2OA 2Q13A 4PNKA 2LOZA 2D9ZA 3VOQA 2COAA 2AEHA 5HE1A 3CXBB 1ZC3B 3ULCA 4KHOA 2YS3A 3HQCA 4K81A 4DX90 2ADZA 4WJ7A 2CRFA 2K2JA 2EJ8A 2E2XA 4TYZA 1H4RA 1FHOA 1FGZA 4HB4B 2J0KA 1MKEA 1K5GB 4A6FB 5FI1A 1U5FA 2DX1A 2AL6A 2D9XA 2GJYA 1BWNA 1UNPA 3ZVRA 5J3TA 2X18A 1I7AA 2PZ1A 3N7CA 2MFQA 2RSGA 3A98B 1P5TA 5DIFB 1P6SA 2RVBB 1W1HA 2Y8GA 4DX8A 1U5DA 3PZDA 4F7UP 1BTNA 3DXDA 3TVVA 1WJ1A 3TCAA 1V61A 1LB1A 2DHKA 5HE2A 2I1JA 1U27A 2VKIA 1DBHA 3T06A 2YRYA 1X11A 3MDBC 1MIZB 2HTHB 2COCA 1FHXA 3KRWA 5CLQB 2Y7BA 1TXDA 2L1CA 1WGQA 4Z2NA 4ZRKA 1IRSA 1X86A 1FAOA 5EFXA 1ZC4B 2UZRA 2DYNA 1BAKA 2EC1A 3CIKA 1M7EA 3PEGA 1U5EA 2I5CA 4HAUB 1V89A 1MIXA 2OTXA 1SGHA 2YT0A 2VRWB 1GC6A 1EVHA 1OQNA 1OY2A 2EMTA 3KSYA 2RGNB 1ZM0A 2Z0PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HAW B;  5HE3 A;  1J0W A;  4A6F A;  2IFS A;  2KUP A;  1KZG A;  3NSU A;  4B6H A;  3O96 A;  2LKO A;  5DHF B;  5C16 A;  1GG3 A;  3D8F A;  2LOX A;  5JP4 A;  3KZ1 A;  4HB2 B;  1XR0 B;  2ELB A;  4NY0 A;  3MPX A;  3G9W A;  4HDO A;  5CLL B;  4YON A;  3KY9 A;  3TO1 A;  4MK0 A;  2P8V A;  2YSZ A;  1OMW A;  2LYD A;  1AWE A;  1WG7 A;  2DA0 A;  2ROV A;  4WVF B;  1ZVR A;  2K2U A;  4F7H A;  2CAY A;  1NI2 A;  1EF1 A;  2MWN B;  5JHH A;  2Y8F A;  2N0Y A;  3PP2 A;  4HB3 B;  1W1D A;  1N3H A;  2D9Y A;  5KQ1 A;  2MDX A;  1PMS A;  4HAT B;  2RNR B;  5C6R A;  4CHM A;  2COD A;  2CY5 A;  2I5F A;  2D9W A;  2DN6 A;  1MK7 B;  4PQ0 A;  3PVL A;  3DXC A;  4TKN A;  2RUK B;  1M7R A;  1TQZ A;  2DHI A;  2KCJ A;  5GOW B;  3F5R A;  3LJU X;  4GN1 A;  1XX0 A;  2N23 A;  2D2Q A;  4EJN A;  3VIA A;  4HAV B;  1FOE A;  4EKU A;  3QIJ A;  2IYB A;  4HDQ A;  1FB8 A;  4K17 A;  1Y5O A;  4P7I A;  1FHW A;  1H10 A;  1I2H A;  2M38 A;  1XCG A;  5KQ4 A;  2JP2 A;  1DYN A;  3P6A A;  1XOD A;  5JHG A;  1QC6 A;  2D4Q A;  3WYF B;  2YT1 A;  5KCV A;  1Z87 A;  4H8S A;  1XD4 A;  4HHV A;  4KAX B;  2GS0 A;  3HK0 A;  2DYQ A;  2LUL A;  3V5W A;  4C0A A;  4HB0 B;  4NSW A;  3F0W A;  1X1G A;  4MT7 A;  4F7G A;  3AU4 A;  2W2W A;  1B55 A;  5C5B B;  2DHJ A;  1NTY A;  4GZU A;  4KHB B;  2FJL A;  5LON B;  1UPR A;  3ULB A;  2I1K A;  4EMO A;  3PVU A;  2GCJ A;  3U8Z A;  3TFM A;  1V5P A;  5D3X A;  2G35 A;  1AQC A;  1ISN A;  2CY4 A;  2OQB A;  2HE7 A;  5J3Q A;  5LOP B;  5C79 A;  2YF0 A;  5J3Y A;  3WA0 A;  2W2X D;  2K00 A;  4DBB A;  5D3Y A;  4Y94 A;  3HW2 B;  1P3R A;  4CYE A;  2D10 A;  3P7Z A;  2KGX B;  1RJ2 A;  3X23 A;  1BTK A;  1UNR A;  3KRX A;  1V5U A;  3ODO A;  3QWM A;  1EAZ A;  4GMX B;  2NZ8 B;  2VSZ A;  4KHA A;  2M14 A;  2J0M A;  3BIN A;  1KI1 B;  2D11 A;  2DTC A;  2ELA A;  2P0H A;  2QKM A;  3AJ4 A;  4MY6 A;  1E5W A;  3TW1 A;  3A8Q A;  2Z0Q A;  2DX5 A;  4K2P A;  2NMB A;  1RRP B;  3PG7 A;  2H7E A;  5DHA B;  1KZ7 A;  1WJM A;  2DLW A;  2P0F A;  1K5D B;  3SV1 A;  3SYX A;  1WVH A;  4HAZ B;  4D0N B;  1UNQ A;  4KVG B;  2MKR A;  2GCL A;  2J0J A;  2EMS A;  4IOY X;  5HE0 A;  3U7D A;  1Y19 B;  3DXE A;  2J59 M;  1MK9 B;  1NU2 A;  3SO6 A;  3FM8 C;  1V88 A;  5C5B A;  1X1F A;  2XQN M;  2QKL A;  4L6E A;  5D3W A;  3SUZ A;  2BCJ A;  3FSS A;  4A6K A;  1PLS A;  1WI1 A;  3FEH A;  1XKE A;  5D27 A;  4ZRJ A;  2UZS A;  2YVC A;  1FGY A;  3PVW A;  2W2X C;  1EGX A;  3A8P A;  3ODX A;  1J19 A;  1DDV A;  1WGU A;  5FI0 A;  1LW3 A;  2COF A;  4DXA B;  1X05 A;  2YS1 A;  1GC7 A;  1U5G A;  1UEF A;  2V76 A;  1QQG A;  2ROZ B;  1DRO A;  2R09 A;  3RCP A;  2YS5 A;  3ML4 A;  4Z2M B;  3PSC A;  4CHJ A;  5D3V A;  2ZPY A;  2H7D A;  1V5M A;  4IFS A;  4GXB A;  2L2I A;  2D9V A;  2RLO A;  4HAY B;  1MAI A;  4A5K A;  2DKQ A;  3SNH A;  1SHC A;  1W1G A;  3D8D A;  4IAP A;  4GPT B;  1DDW A;  1MPH A;  3GYO A;  3ZDT A;  4HAX B;  2UVM A;  2DKP A;  3BJI A;  4ZRI A;  1U29 A;  2R0D A;  4WSF A;  1TJ6 A;  4BBK A;  5DI9 B;  4A6H A;  1NTV A;  2Z0O A;  4XWX A;  3IVF A;  3D8E A;  3OAN A;  2P0D A;  1DDM A;  1PFJ A;  3M1I B;  3GYP A;  4GMV A;  1UPQ A;  1U2B A;  3QBV B;  5L81 A;  1ZSQ A;  4YL8 A;  3UZT A;  2DFK A;  5JLJ B;  1Q67 A;  5DH9 B;  2LG1 A;  3ODW A;  3AU5 A;  4K2O A;  2Q13 A;  4PNK A;  2LOZ A;  2D9Z A;  3VOQ A;  2COA A;  2AEH A;  5HE1 A;  3CXB B;  1ZC3 B;  3ULC A;  4KHO A;  2YS3 A;  3HQC A;  4K81 A;  4DX9 0;  2ADZ A;  4WJ7 A;  2CRF A;  2K2J A;  2EJ8 A;  2E2X A;  4TYZ A;  1H4R A;  1FHO A;  1FGZ A;  4HB4 B;  2J0K A;  1MKE A;  1K5G B;  4A6F B;  5FI1 A;  1U5F A;  2DX1 A;  2AL6 A;  2D9X A;  2GJY A;  1BWN A;  1UNP A;  3ZVR A;  5J3T A;  2X18 A;  1I7A A;  2PZ1 A;  3N7C A;  2MFQ A;  2RSG A;  3A98 B;  1P5T A;  5DIF B;  1P6S A;  2RVB B;  1W1H A;  2Y8G A;  4DX8 A;  1U5D A;  3PZD A;  4F7U P;  1BTN A;  3DXD A;  3TVV A;  1WJ1 A;  3TCA A;  1V61 A;  1LB1 A;  2DHK A;  5HE2 A;  2I1J A;  1U27 A;  2VKI A;  1DBH A;  3T06 A;  2YRY A;  1X11 A;  3MDB C;  1MIZ B;  2HTH B;  2COC A;  1FHX A;  3KRW A;  5CLQ B;  2Y7B A;  1TXD A;  2L1C A;  1WGQ A;  4Z2N A;  4ZRK A;  1IRS A;  1X86 A;  1FAO A;  5EFX A;  1ZC4 B;  2UZR A;  2DYN A;  1BAK A;  2EC1 A;  3CIK A;  1M7E A;  3PEG A;  1U5E A;  2I5C A;  4HAU B;  1V89 A;  1MIX A;  2OTX A;  1SGH A;  2YT0 A;  2VRW B;  1GC6 A;  1EVH A;  1OQN A;  1OY2 A;  2EMT A;  3KSY A;  2RGN B;  1ZM0 A;  2Z0P A; 
#chains in the Genus database with same CATH topology
 4HAW B;  5HE3 A;  1J0W A;  4A6F A;  2IFS A;  2KUP A;  4GOU A;  1KZG A;  3NSU A;  4GNK B;  4B6H A;  3O96 A;  2LKO A;  5DHF B;  5C16 A;  1GG3 A;  3D8F A;  2LOX A;  5I2M A;  5JP4 A;  3KZ1 A;  4HB2 B;  1XR0 B;  2ELB A;  4NY0 A;  3MPX A;  3NWD A;  3G9W A;  4HDO A;  5CLL B;  4YON A;  3KY9 A;  3TO1 A;  2KUQ A;  4MK0 A;  4OSN A;  2P8V A;  2YSZ A;  1OMW A;  2LYD A;  1AWE A;  1WG7 A;  2DA0 A;  2ROV A;  4WVF B;  1ZVR A;  2K2U A;  4F7H A;  2CAY A;  1NI2 A;  1EF1 A;  2MWN B;  5JHH A;  2Y8F A;  2N0Y A;  3PP2 A;  4HB3 B;  1W1D A;  1N3H A;  2D9Y A;  5KQ1 A;  2MDX A;  1PMS A;  4HAT B;  3NW8 A;  2RNR B;  3OHM B;  5C6R A;  4CHM A;  2COD A;  2CY5 A;  2I5F A;  1T77 A;  2D9W A;  2Z14 A;  2DN6 A;  1MK7 B;  4PQ0 A;  3PVL A;  3DXC A;  4TKN A;  2RUK B;  1M7R A;  1TQZ A;  2DHI A;  2KCJ A;  5GOW B;  3F5R A;  3LJU X;  4GN1 A;  1XX0 A;  2N23 A;  2D2Q A;  4EJN A;  3FVC A;  3VIA A;  4HAV B;  1FOE A;  4EKU A;  5IRS A;  3QIJ A;  2IYB A;  4HDQ A;  1FB8 A;  4K17 A;  1Y5O A;  4P7I A;  1FHW A;  1H10 A;  4HSI A;  2Z59 A;  1I2H A;  2M38 A;  1XCG A;  5KQ4 A;  2JP2 A;  1DYN A;  3P6A A;  1XOD A;  5JHG A;  1QC6 A;  2D4Q A;  3WYF B;  2YT1 A;  5KCV A;  1Z87 A;  4H8S A;  1XD4 A;  4HHV A;  4KAX B;  2GS0 A;  3HK0 A;  2DYQ A;  2LUL A;  3V5W A;  2Z4D A;  4C0A A;  4HB0 B;  4NSW A;  3F0W A;  1X1G A;  4MT7 A;  4F7G A;  3AU4 A;  2W2W A;  1B55 A;  5C5B B;  2DHJ A;  1NTY A;  4GZU A;  4KHB B;  2FJL A;  5LON B;  4CSQ A;  1UPR A;  3ULB A;  2NBV A;  2I1K A;  4EMO A;  3PVU A;  2GCJ A;  3U8Z A;  3TFM A;  1V5P A;  5D3X A;  2G35 A;  1AQC A;  1ISN A;  2CY4 A;  2OQB A;  3HSA A;  2HE7 A;  5J3Q A;  5LOP B;  5C79 A;  2YF0 A;  5J3Y A;  4L1R A;  3WA0 A;  2W2X D;  2K00 A;  4DBB A;  5D3Y A;  4Y94 A;  3HW2 B;  1P3R A;  4CYE A;  4QXA B;  2D10 A;  3P7Z A;  2KGX B;  1RJ2 A;  3X23 A;  1BTK A;  1UNR A;  3KRX A;  1V5U A;  3ODO A;  2FJU B;  1EAZ A;  3QWM A;  4GMX B;  2NZ8 B;  2VSZ A;  4KHA A;  2M14 A;  2J0M A;  2P0H A;  3BIN A;  1KI1 B;  2D11 A;  2DTC A;  2ELA A;  2QKM A;  3AJ4 A;  4MY6 A;  1E5W A;  4QJ3 B;  3TW1 A;  3A8Q A;  2K49 A;  2Z0Q A;  2KIG A;  2DX5 A;  4QJ4 B;  4K2P A;  2NMB A;  1RRP B;  3PG7 A;  2H7E A;  3B77 A;  5DHA B;  1KZ7 A;  1WJM A;  2DLW A;  2P0F A;  1K5D B;  3SV1 A;  3SYX A;  1WVH A;  4HAZ B;  4D0N B;  1UNQ A;  4KVG B;  2MKR A;  2GCL A;  2J0J A;  2EMS A;  4IOY X;  5HE0 A;  3U7D A;  1Y19 B;  3DXE A;  2J59 M;  4OT1 A;  1MK9 B;  1NU2 A;  3SO6 A;  3FM8 C;  1V88 A;  5C5B A;  1X1F A;  2XQN M;  2QKL A;  2R2Y A;  4L6E A;  5D3W A;  3SUZ A;  4KHB A;  2BCJ A;  3FSS A;  4A6K A;  1PLS A;  1WI1 A;  3FEH A;  1XKE A;  5D27 A;  4ZRJ A;  2UZS A;  2YVC A;  1FGY A;  3PVW A;  2Z13 A;  2W2X C;  1EGX A;  3A8P A;  3ODX A;  1J19 A;  1DDV A;  1WGU A;  5FI0 A;  1LW3 A;  2COF A;  4DXA B;  1X05 A;  2YS1 A;  3NWA A;  1GC7 A;  1U5G A;  1UEF A;  2V76 A;  1QQG A;  2ROZ B;  5M4Y B;  1DRO A;  2R09 A;  3RCP A;  2YS5 A;  2KIE A;  3ML4 A;  4Z2M B;  3PSC A;  4CHJ A;  5D3V A;  2ZPY A;  2H7D A;  1V5M A;  4IFS A;  4GXB A;  2L2I A;  2D9V A;  2RLO A;  4HAY B;  1ZYI A;  1MAI A;  4A5K A;  2DKQ A;  3SNH A;  1SHC A;  1W1G A;  3D8D A;  4IAP A;  4GPT B;  1DDW A;  2KR0 A;  1MPH A;  3GYO A;  5I2S A;  3ZDT A;  4HAX B;  2UVM A;  2DKP A;  3BJI A;  4ZRI A;  1U29 A;  2R0D A;  4WSF A;  1TJ6 A;  4BBK A;  5DI9 B;  4A6H A;  1NTV A;  2Z0O A;  4XWX A;  3IVF A;  3D8E A;  3OAN A;  2P0D A;  1DDM A;  3A58 A;  1PFJ A;  3M1I B;  3GYP A;  4GMV A;  1UPQ A;  1U2B A;  3QBV B;  5L81 A;  1ZSQ A;  4YL8 A;  3UZT A;  2DFK A;  5JLJ B;  1Q67 A;  3U12 A;  5DH9 B;  2LG1 A;  3ODW A;  3AU5 A;  4K2O A;  2Q13 A;  4PNK A;  5LG4 B;  2LOZ A;  2D9Z A;  3NWF A;  3VOQ A;  2COA A;  2AEH A;  5HE1 A;  3CXB B;  1ZC3 B;  3ULC A;  4KHO A;  2YS3 A;  3HQC A;  4K81 A;  4DX9 0;  2ADZ A;  4D6W A;  4WJ7 A;  2CRF A;  2K2J A;  2EJ8 A;  2E2X A;  2ZKM X;  4TYZ A;  1H4R A;  1FHO A;  1FGZ A;  4HB4 B;  2J0K A;  1MKE A;  1K5G B;  4A6F B;  3DCX A;  5FI1 A;  1U5F A;  2GUM A;  2DX1 A;  2K8E A;  2AL6 A;  2D9X A;  2GJY A;  1BWN A;  1UNP A;  3ZVR A;  5J3T A;  2X18 A;  1I7A A;  2PZ1 A;  3N7C A;  2MFQ A;  2RSG A;  3A98 B;  2YT2 A;  1P5T A;  5DIF B;  1P6S A;  2RVB B;  2RRF A;  1W1H A;  2Y8G A;  3HIE A;  4DX8 A;  1U5D A;  3PZD A;  4F7U P;  1BTN A;  3DXD A;  3TVV A;  1WJ1 A;  3TCA A;  1MI1 A;  1V61 A;  1LB1 A;  2DHK A;  5HE2 A;  2I1J A;  1U27 A;  2VKI A;  1DBH A;  3T06 A;  2YRY A;  1X11 A;  3MDB C;  1MIZ B;  2HTH B;  2COC A;  1FHX A;  3KRW A;  5CLQ B;  2Y7B A;  1TXD A;  2L1C A;  1WGQ A;  4Z2N A;  4ZRK A;  1IRS A;  1X86 A;  1FAO A;  5EFX A;  1ZC4 B;  4QJ5 B;  2UZR A;  2DYN A;  1BAK A;  2EC1 A;  3CIK A;  1M7E A;  3PEG A;  1U5E A;  2I5C A;  4HAU B;  1V89 A;  1MIX A;  2OTX A;  1SGH A;  2YT0 A;  2VRW B;  1GC6 A;  1EVH A;  1OQN A;  4DIX A;  1OY2 A;  2EMT A;  3KSY A;  2RGN B;  1ZM0 A;  2Z0P A; 
#chains in the Genus database with same CATH homology
 4HAW B;  5HE3 A;  1J0W A;  4A6F A;  2IFS A;  2KUP A;  1KZG A;  3NSU A;  4B6H A;  3O96 A;  2LKO A;  5DHF B;  5C16 A;  1GG3 A;  3D8F A;  2LOX A;  5JP4 A;  3KZ1 A;  4HB2 B;  1XR0 B;  2ELB A;  4NY0 A;  3MPX A;  3G9W A;  4HDO A;  5CLL B;  4YON A;  3KY9 A;  3TO1 A;  4MK0 A;  2P8V A;  2YSZ A;  1OMW A;  2LYD A;  1AWE A;  1WG7 A;  2DA0 A;  2ROV A;  4WVF B;  1ZVR A;  2K2U A;  4F7H A;  2CAY A;  1NI2 A;  1EF1 A;  2MWN B;  5JHH A;  2Y8F A;  2N0Y A;  3PP2 A;  4HB3 B;  1W1D A;  1N3H A;  2D9Y A;  5KQ1 A;  2MDX A;  1PMS A;  4HAT B;  2RNR B;  5C6R A;  4CHM A;  2COD A;  2CY5 A;  2I5F A;  2D9W A;  2DN6 A;  1MK7 B;  4PQ0 A;  3PVL A;  3DXC A;  4TKN A;  2RUK B;  1M7R A;  1TQZ A;  2DHI A;  2KCJ A;  5GOW B;  3F5R A;  3LJU X;  4GN1 A;  1XX0 A;  2N23 A;  2D2Q A;  4EJN A;  3VIA A;  4HAV B;  1FOE A;  4EKU A;  3QIJ A;  2IYB A;  4HDQ A;  1FB8 A;  4K17 A;  1Y5O A;  4P7I A;  1FHW A;  1H10 A;  1I2H A;  2M38 A;  1XCG A;  5KQ4 A;  2JP2 A;  1DYN A;  3P6A A;  1XOD A;  5JHG A;  1QC6 A;  2D4Q A;  3WYF B;  2YT1 A;  5KCV A;  1Z87 A;  4H8S A;  1XD4 A;  4HHV A;  4KAX B;  2GS0 A;  3HK0 A;  2DYQ A;  2LUL A;  3V5W A;  4C0A A;  4HB0 B;  4NSW A;  3F0W A;  1X1G A;  4MT7 A;  4F7G A;  3AU4 A;  2W2W A;  1B55 A;  5C5B B;  2DHJ A;  1NTY A;  4GZU A;  4KHB B;  2FJL A;  5LON B;  1UPR A;  3ULB A;  2I1K A;  4EMO A;  3PVU A;  2GCJ A;  3U8Z A;  3TFM A;  1V5P A;  5D3X A;  2G35 A;  1AQC A;  1ISN A;  2CY4 A;  2OQB A;  2HE7 A;  5J3Q A;  5LOP B;  5C79 A;  2YF0 A;  5J3Y A;  3WA0 A;  2W2X D;  2K00 A;  4DBB A;  5D3Y A;  4Y94 A;  3HW2 B;  1P3R A;  4CYE A;  2D10 A;  3P7Z A;  2KGX B;  1RJ2 A;  3X23 A;  1BTK A;  1UNR A;  3KRX A;  1V5U A;  3ODO A;  3QWM A;  1EAZ A;  4GMX B;  2NZ8 B;  2VSZ A;  4KHA A;  2M14 A;  2J0M A;  3BIN A;  1KI1 B;  2D11 A;  2DTC A;  2ELA A;  2P0H A;  2QKM A;  3AJ4 A;  4MY6 A;  1E5W A;  3TW1 A;  3A8Q A;  2Z0Q A;  2DX5 A;  4K2P A;  2NMB A;  1RRP B;  3PG7 A;  2H7E A;  5DHA B;  1KZ7 A;  1WJM A;  2DLW A;  2P0F A;  1K5D B;  3SV1 A;  3SYX A;  1WVH A;  4HAZ B;  4D0N B;  1UNQ A;  4KVG B;  2MKR A;  2GCL A;  2J0J A;  2EMS A;  4IOY X;  5HE0 A;  3U7D A;  1Y19 B;  3DXE A;  2J59 M;  1MK9 B;  1NU2 A;  3SO6 A;  3FM8 C;  1V88 A;  5C5B A;  1X1F A;  2XQN M;  2QKL A;  4L6E A;  5D3W A;  3SUZ A;  2BCJ A;  3FSS A;  4A6K A;  1PLS A;  1WI1 A;  3FEH A;  1XKE A;  5D27 A;  4ZRJ A;  2UZS A;  2YVC A;  1FGY A;  3PVW A;  2W2X C;  1EGX A;  3A8P A;  3ODX A;  1J19 A;  1DDV A;  1WGU A;  5FI0 A;  1LW3 A;  2COF A;  4DXA B;  1X05 A;  2YS1 A;  1GC7 A;  1U5G A;  1UEF A;  2V76 A;  1QQG A;  2ROZ B;  1DRO A;  2R09 A;  3RCP A;  2YS5 A;  3ML4 A;  4Z2M B;  3PSC A;  4CHJ A;  5D3V A;  2ZPY A;  2H7D A;  1V5M A;  4IFS A;  4GXB A;  2L2I A;  2D9V A;  2RLO A;  4HAY B;  1MAI A;  4A5K A;  2DKQ A;  3SNH A;  1SHC A;  1W1G A;  3D8D A;  4IAP A;  4GPT B;  1DDW A;  1MPH A;  3GYO A;  3ZDT A;  4HAX B;  2UVM A;  2DKP A;  3BJI A;  4ZRI A;  1U29 A;  2R0D A;  4WSF A;  1TJ6 A;  4BBK A;  5DI9 B;  4A6H A;  1NTV A;  2Z0O A;  4XWX A;  3IVF A;  3D8E A;  3OAN A;  2P0D A;  1DDM A;  1PFJ A;  3M1I B;  3GYP A;  4GMV A;  1UPQ A;  1U2B A;  3QBV B;  5L81 A;  1ZSQ A;  4YL8 A;  3UZT A;  2DFK A;  5JLJ B;  1Q67 A;  5DH9 B;  2LG1 A;  3ODW A;  3AU5 A;  4K2O A;  2Q13 A;  4PNK A;  2LOZ A;  2D9Z A;  3VOQ A;  2COA A;  2AEH A;  5HE1 A;  3CXB B;  1ZC3 B;  3ULC A;  4KHO A;  2YS3 A;  3HQC A;  4K81 A;  4DX9 0;  2ADZ A;  4WJ7 A;  2CRF A;  2K2J A;  2EJ8 A;  2E2X A;  4TYZ A;  1H4R A;  1FHO A;  1FGZ A;  4HB4 B;  2J0K A;  1MKE A;  1K5G B;  4A6F B;  5FI1 A;  1U5F A;  2DX1 A;  2AL6 A;  2D9X A;  2GJY A;  1BWN A;  1UNP A;  3ZVR A;  5J3T A;  2X18 A;  1I7A A;  2PZ1 A;  3N7C A;  2MFQ A;  2RSG A;  3A98 B;  1P5T A;  5DIF B;  1P6S A;  2RVB B;  1W1H A;  2Y8G A;  4DX8 A;  1U5D A;  3PZD A;  4F7U P;  1BTN A;  3DXD A;  3TVV A;  1WJ1 A;  3TCA A;  1V61 A;  1LB1 A;  2DHK A;  5HE2 A;  2I1J A;  1U27 A;  2VKI A;  1DBH A;  3T06 A;  2YRY A;  1X11 A;  3MDB C;  1MIZ B;  2HTH B;  2COC A;  1FHX A;  3KRW A;  5CLQ B;  2Y7B A;  1TXD A;  2L1C A;  1WGQ A;  4Z2N A;  4ZRK A;  1IRS A;  1X86 A;  1FAO A;  5EFX A;  1ZC4 B;  2UZR A;  2DYN A;  1BAK A;  2EC1 A;  3CIK A;  1M7E A;  3PEG A;  1U5E A;  2I5C A;  4HAU B;  1V89 A;  1MIX A;  2OTX A;  1SGH A;  2YT0 A;  2VRW B;  1GC6 A;  1EVH A;  1OQN A;  1OY2 A;  2EMT A;  3KSY A;  2RGN B;  1ZM0 A;  2Z0P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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