1B55A

Ph domain from bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
169
structure length
163
Chain Sequence
AAVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIPRRMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILEN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords TYROSINE-PROTEIN KINASE BTK
total genus 33
structure length 163
sequence length 169
chains with identical sequence B
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 1999-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF00779 BTK BTK motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1b55A00
2V76A 4PNKA 2ROZB 4EMOA 2K2UA 1ISNA 4YONA 2J59M 1V88A 2UZRA 1Z87A 1KZ7A 2OQBA 1WJMA 2LULA 1K5GB 3SUZA 5FI0A 3PG7A 4CYEA 1ZSQA 4KHBB 2YS1A 4L6EA 3P7ZA 2Y8GA 1U27A 2EC1A 3DXDA 1M7RA 2DTCA 5D3XA 1XD4A 5C5BB 4KHOA 1PLSA 3ODXA 4ZRIA 4XWXA 4K2PA 2D2QA 4CHJA 4PQ0A 1DBHA 4GN1A 1SGHA 2RLOA 2DX5A 1RRPB 1WG7A 3LJUX 2Y7BA 1FHXA 1WJ1A 2YVCA 5D3YA 4GPTB 3V5WA 2RUKB 2R0DA 2GCJA 2MWNB 4F7HA 3PSCA 2DKQA 1XODA 3P6AA 4Z2MB 1X05A 2L1CA 1UPRA 2N23A 5J3YA 1V61A 1FAOA 1V5PA 1FHWA 5HE3A 3U8ZA 2P0HA 3BJIA 4BBKA 1BTNA 2EMTA 1KI1B 1XX0A 2LYDA 5C16A 3O96A 1N3HA 1MK9B 1I2HA 3ULCA 2UZSA 3NSUA 1MAIA 4KVGB 2D9YA 2XQNM 1P6SA 1EGXA 3FM8C 3QBVB 4TYZA 1FHOA 4HAYB 1V5MA 2D9WA 1K5DB 5J3TA 1U29A 4HB2B 2YF0A 5DHFB 3DXCA 3KSYA 4K2OA 3T06A 3FEHA 2QKMA 3TFMA 3CIKA 2H7EA 4HAWB 2K2JA 2W2XD 1W1HA 3WA0A 4A6FA 2YSZA 3U7DA 2H7DA 2J0JA 2VKIA 2Q13A 5HE2A 1WGUA 3M1IB 1Y19B 4CHMA 1FB8A 3D8FA 5D3VA 3SO6A 2ADZA 2UVMA 3ODWA 1KZGA 1BAKA 4HB3B 3ZDTA 2Z0PA 4F7GA 2GCLA 2D9VA 4ZRJA 1U5DA 1AQCA 2CRFA 2EJ8A 1BTKA 5KQ4A 3SNHA 2HE7A 5D3WA 4MK0A 1LB1A 5LONB 2I1KA 1DDVA 2ROVA 5KQ1A 2I1JA 3A8QA 2D11A 2M38A 2ELBA 2LKOA 4HATB 5FI1A 4EKUA 2DYNA 2D4QA 4A6FB 4DX90 1P3RA 2D9XA 1EVHA 2COAA 2YS5A 1I7AA 5CLQB 5DI9B 3TCAA 1WVHA 3SYXA 2DHIA 4C0AA 5J3QA 5JHGA 3A98B 1MKEA 2CY4A 4P7IA 2I5FA 3D8EA 2J0MA 2DFKA 5D27A 1H4RA 5HE1A 2LG1A 4WSFA 3ULBA 3VIAA 2M14A 3UZTA 2ELAA 4HB4B 1XKEA 3QIJA 2QKLA 1ZVRA 5KCVA 2AL6A 3OANA 2YRYA 4HDOA 1MIXA 1NTYA 4WJ7A 3TVVA 3IVFA 3CXBB 2N0YA 3F0WA 4NY0A 2NMBA 1NTVA 1MK7B 1WGQA 2RGNB 2G35A 3PVWA 3PEGA 4HDQA 3PVUA 4IFSA 4HAVB 5HE0A 4DBBA 1V5UA 1WI1A 1UNQA 3KZ1A 4ZRKA 1P5TA 3MDBC 3ODOA 1XCGA 2Y8FA 4YL8A 1DROA 3PZDA 5JHHA 3A8PA 3ZVRA 4KAXB 1X1GA 4D0NB 1X86A 1BWNA 2YT0A 2ZPYA 3FSSA 2BCJA 3HQCA 3TO1A 1DYNA 2IFSA 2J0KA 5L81A 3GYOA 4F7UP 1NU2A 4GMVA 2KCJA 2MFQA 3HW2B 3F5RA 1LW3A 2L2IA 2RNRB 2DN6A 2YT1A 4Y94A 2P0DA 2MDXA 5CLLB 1AWEA 4A6KA 1EAZA 1FGZA 1ZC3B 1IRSA 4DXAB 4H8SA 4MT7A 2DA0A 2FJLA 2HTHB 3AU5A 1U5EA 1PMSA 1NI2A 1RJ2A 2K00A 5C6RA 1OY2A 3KRWA 1UEFA 4DX8A 2DLWA 2CAYA 4B6HA 1V89A 2VSZA 5JP4A 4MY6A 3HK0A 3PP2A 5LOPB 1OQNA 1U5GA 3KY9A 4K17A 4GMXB 1QC6A 5EFXA 3KRXA 4GXBA 3N7CA 2DX1A 2COFA 2PZ1A 2W2WA 1PFJA 5DH9B 3BINA 2GS0A 2CODA 4Z2NA 2OTXA 3MPXA 4HAXB 2DHKA 5C79A 2Z0OA 1GG3A 2COCA 4HHVA 2DYQA 3GYPA 4HAZB 3AJ4A 2P8VA 1TXDA 4GZUA 2X18A 1GC6A 5DIFB 1X1FA 2E2XA 3D8DA 4K81A 2KUPA 5DHAB 1ZC4B 1EF1A 3ML4A 1B55A 1OMWA 2KGXB 4A6HA 2RVBB 1MPHA 2GJYA 2I5CA 1W1GA 2W2XC 1ZM0A 2Z0QA 1W1DA 4IAPA 1J0WA 2IYBA 3G9WA 2LOXA 1Q67A 3QWMA 2NZ8B 1H10A 1M7EA 1FGYA 1U2BA 3X23A 2RSGA 2D10A 3VOQA 1DDMA 3WYFB 1Y5OA 1UPQA 1J19A 2EMSA 2JP2A 1MIZB 1E5WA 2DHJA 2LOZA 1TJ6A 1X11A 3RCPA 1TQZA 3SV1A 1QQGA 2YS3A 2P0FA 3PVLA 2CY5A 4WVFB 5GOWB 1SHCA 2MKRA 4EJNA 5JLJB 1XR0B 4NSWA 3AU4A 4IOYX 2VRWB 2DKPA 4A5KA 1FOEA 4HAUB 2D9ZA 2R09A 1UNRA 1UNPA 3DXEA 2AEHA 1U5FA 5C5BA 1DDWA 4HB0B 4KHAA 3TW1A 4TKNA 1GC7A
chains in the Genus database with same CATH superfamily
2V76A 4PNKA 2ROZB 4EMOA 2K2UA 1ISNA 4YONA 2J59M 1V88A 2UZRA 1Z87A 1KZ7A 2OQBA 1WJMA 2LULA 1K5GB 3SUZA 5FI0A 3PG7A 2KR0A 4CYEA 1ZSQA 2K8EA 4KHBB 2YS1A 4L6EA 3P7ZA 2Y8GA 1U27A 2EC1A 3DXDA 2KIEA 1M7RA 2DTCA 5D3XA 1XD4A 4GNKB 3U12A 5C5BB 4KHOA 1PLSA 3ODXA 4ZRIA 4XWXA 4K2PA 2D2QA 4CHJA 4PQ0A 1DBHA 4GN1A 1SGHA 2RLOA 2DX5A 1RRPB 1WG7A 3LJUX 2Y7BA 1FHXA 1WJ1A 2YVCA 3NWDA 5D3YA 4GPTB 3V5WA 2RUKB 2R0DA 2GCJA 2MWNB 4F7HA 3PSCA 2DKQA 1XODA 3P6AA 4Z2MB 1X05A 2L1CA 1UPRA 2N23A 5J3YA 1V61A 1FAOA 1V5PA 1FHWA 5HE3A 3U8ZA 2P0HA 3BJIA 4BBKA 1BTNA 2EMTA 1KI1B 1XX0A 2LYDA 5C16A 3O96A 1N3HA 1MK9B 1I2HA 3ULCA 2UZSA 3NSUA 1MAIA 4KVGB 1MI1A 2D9YA 2XQNM 4DIXA 1P6SA 1EGXA 3FM8C 3QBVB 4TYZA 1FHOA 4HAYB 1V5MA 2D9WA 1K5DB 5J3TA 1U29A 4HB2B 2YF0A 5DHFB 3DXCA 3KSYA 4K2OA 3T06A 3FEHA 2QKMA 3TFMA 3CIKA 4QJ3B 2H7EA 4HAWB 2K2JA 5M4YB 2W2XD 1W1HA 3WA0A 4A6FA 2YSZA 3U7DA 2H7DA 2J0JA 2VKIA 2Q13A 2NBVA 5HE2A 1WGUA 3M1IB 1Y19B 4CHMA 1FB8A 3D8FA 5D3VA 3SO6A 2FJUB 2ADZA 2UVMA 2Z59A 3ODWA 1KZGA 1BAKA 4HB3B 3ZDTA 2Z0PA 4F7GA 2GCLA 2D9VA 4ZRJA 1U5DA 1AQCA 2CRFA 2EJ8A 3NW8A 1BTKA 5KQ4A 3SNHA 2HE7A 5D3WA 4MK0A 1LB1A 5LONB 2I1KA 1DDVA 2ROVA 5KQ1A 2I1JA 3A8QA 2D11A 2M38A 2ELBA 2LKOA 4HATB 5FI1A 4EKUA 2DYNA 2D4QA 3B77A 4A6FB 4DX90 1P3RA 2D9XA 1EVHA 2COAA 2YS5A 1I7AA 5CLQB 5DI9B 3TCAA 1WVHA 3SYXA 2DHIA 4C0AA 5J3QA 5JHGA 3A98B 1MKEA 3NWAA 2GUMA 2CY4A 4P7IA 2I5FA 3D8EA 2J0MA 2DFKA 5D27A 2Z13A 1H4RA 5HE1A 2LG1A 4WSFA 3ULBA 3VIAA 2M14A 3UZTA 2ELAA 4HB4B 1XKEA 3QIJA 2QKLA 1ZVRA 3OHMB 2AL6A 5KCVA 2R2YA 2RRFA 3OANA 4QXAB 2YRYA 5IRSA 4OT1A 4HDOA 1MIXA 1NTYA 4WJ7A 3TVVA 3IVFA 3CXBB 2Z14A 2N0YA 3F0WA 4NY0A 2NMBA 1NTVA 1MK7B 1WGQA 2RGNB 2G35A 3PVWA 3PEGA 4HDQA 3PVUA 4IFSA 4HAVB 5HE0A 4DBBA 1V5UA 1WI1A 1UNQA 2ZKMX 3KZ1A 4ZRKA 1P5TA 3MDBC 3ODOA 1XCGA 2Y8FA 4YL8A 1DROA 3PZDA 5JHHA 3A8PA 3ZVRA 4KAXB 1X1GA 4D0NB 1X86A 1BWNA 2YT0A 2ZPYA 3FSSA 4L1RA 2BCJA 3HQCA 3TO1A 3FVCA 1DYNA 2IFSA 2J0KA 1T77A 5L81A 1ZYIA 3GYOA 4F7UP 1NU2A 4GMVA 2KCJA 2MFQA 3HW2B 3F5RA 1LW3A 2L2IA 2RNRB 2DN6A 2YT1A 4Y94A 2P0DA 2MDXA 5CLLB 1AWEA 4A6KA 1EAZA 1FGZA 1ZC3B 1IRSA 4DXAB 4H8SA 2KIGA 2DA0A 4MT7A 2FJLA 2HTHB 3AU5A 1U5EA 1PMSA 1NI2A 1RJ2A 2K00A 5C6RA 1OY2A 3KRWA 1UEFA 4DX8A 2DLWA 2CAYA 4GOUA 2Z4DA 4QJ5B 4B6HA 1V89A 3NWFA 2VSZA 5JP4A 5I2MA 4MY6A 3A58A 3HK0A 3PP2A 3HSAA 5LOPB 1OQNA 5LG4B 1U5GA 3KY9A 3DCXA 4K17A 4GMXB 1QC6A 5EFXA 3KRXA 4GXBA 3N7CA 2DX1A 2COFA 2PZ1A 2W2WA 1PFJA 5DH9B 3HIEA 3BINA 2GS0A 2CODA 4Z2NA 2OTXA 3MPXA 4HAXB 2DHKA 5C79A 2Z0OA 2YT2A 1GG3A 2COCA 4QJ4B 4HHVA 2DYQA 3GYPA 4HAZB 3AJ4A 2P8VA 1TXDA 4GZUA 2X18A 1GC6A 5DIFB 1X1FA 2E2XA 4D6WA 3D8DA 4K81A 2KUPA 5DHAB 1ZC4B 1EF1A 3ML4A 1B55A 1OMWA 2KGXB 4A6HA 2RVBB 1MPHA 2GJYA 2I5CA 1W1GA 2W2XC 1ZM0A 2Z0QA 1W1DA 4IAPA 1J0WA 2IYBA 3G9WA 2LOXA 4HSIA 1Q67A 3QWMA 2NZ8B 1H10A 4OSNA 1M7EA 1FGYA 1U2BA 3X23A 2RSGA 2D10A 3VOQA 1DDMA 3WYFB 1Y5OA 1UPQA 1J19A 2EMSA 2JP2A 1MIZB 1E5WA 2DHJA 2LOZA 1TJ6A 1X11A 3RCPA 2KUQA 1TQZA 3SV1A 1QQGA 2YS3A 2P0FA 3PVLA 2CY5A 2K49A 4WVFB 5GOWB 1SHCA 2MKRA 4EJNA 5JLJB 1XR0B 4NSWA 3AU4A 4KHBA 4IOYX 2VRWB 2DKPA 4A5KA 5I2SA 1FOEA 4HAUB 4CSQA 2D9ZA 2R09A 1UNRA 1UNPA 3DXEA 2AEHA 1U5FA 5C5BA 1DDWA 4HB0B 4KHAA 3TW1A 4TKNA 1GC7A
chains in the Genus database with same CATH topology
2V76A 4PNKA 2ROZB 4EMOA 2K2UA 1ISNA 4YONA 2J59M 1V88A 2UZRA 1Z87A 1KZ7A 2OQBA 1WJMA 2LULA 1K5GB 3SUZA 5FI0A 3PG7A 4CYEA 1ZSQA 4KHBB 2YS1A 4L6EA 3P7ZA 2Y8GA 1U27A 2EC1A 3DXDA 1M7RA 2DTCA 5D3XA 1XD4A 5C5BB 4KHOA 1PLSA 3ODXA 4ZRIA 4XWXA 4K2PA 2D2QA 4CHJA 4PQ0A 1DBHA 4GN1A 1SGHA 2RLOA 2DX5A 1RRPB 1WG7A 3LJUX 2Y7BA 1FHXA 1WJ1A 2YVCA 5D3YA 4GPTB 3V5WA 2RUKB 2R0DA 2GCJA 2MWNB 4F7HA 3PSCA 2DKQA 1XODA 3P6AA 4Z2MB 1X05A 2L1CA 1UPRA 2N23A 5J3YA 1V61A 1FAOA 1V5PA 1FHWA 5HE3A 3U8ZA 2P0HA 3BJIA 4BBKA 1BTNA 2EMTA 1KI1B 1XX0A 2LYDA 5C16A 3O96A 1N3HA 1MK9B 1I2HA 3ULCA 2UZSA 3NSUA 1MAIA 4KVGB 2D9YA 2XQNM 1P6SA 1EGXA 3FM8C 3QBVB 4TYZA 1FHOA 4HAYB 1V5MA 2D9WA 1K5DB 5J3TA 1U29A 4HB2B 2YF0A 5DHFB 3DXCA 3KSYA 4K2OA 3T06A 3FEHA 2QKMA 3TFMA 3CIKA 2H7EA 4HAWB 2K2JA 2W2XD 1W1HA 3WA0A 4A6FA 2YSZA 3U7DA 2H7DA 2J0JA 2VKIA 2Q13A 5HE2A 1WGUA 3M1IB 1Y19B 4CHMA 1FB8A 3D8FA 5D3VA 3SO6A 2ADZA 2UVMA 3ODWA 1KZGA 1BAKA 4HB3B 3ZDTA 2Z0PA 4F7GA 2GCLA 2D9VA 4ZRJA 1U5DA 1AQCA 2CRFA 2EJ8A 1BTKA 5KQ4A 3SNHA 2HE7A 5D3WA 4MK0A 1LB1A 5LONB 2I1KA 1DDVA 2ROVA 5KQ1A 2I1JA 3A8QA 2D11A 2M38A 2ELBA 2LKOA 4HATB 5FI1A 4EKUA 2DYNA 2D4QA 4A6FB 4DX90 1P3RA 2D9XA 1EVHA 2COAA 2YS5A 1I7AA 5CLQB 5DI9B 3TCAA 1WVHA 3SYXA 2DHIA 4C0AA 5J3QA 5JHGA 3A98B 1MKEA 2CY4A 4P7IA 2I5FA 3D8EA 2J0MA 2DFKA 5D27A 1H4RA 5HE1A 2LG1A 4WSFA 3ULBA 3VIAA 2M14A 3UZTA 2ELAA 4HB4B 1XKEA 3QIJA 2QKLA 1ZVRA 5KCVA 2AL6A 3OANA 2YRYA 4HDOA 1MIXA 1NTYA 4WJ7A 3TVVA 3IVFA 3CXBB 2N0YA 3F0WA 4NY0A 2NMBA 1NTVA 1MK7B 1WGQA 2RGNB 2G35A 3PVWA 3PEGA 4HDQA 3PVUA 4IFSA 4HAVB 5HE0A 4DBBA 1V5UA 1WI1A 1UNQA 3KZ1A 4ZRKA 1P5TA 3MDBC 3ODOA 1XCGA 2Y8FA 4YL8A 1DROA 3PZDA 5JHHA 3A8PA 3ZVRA 4KAXB 1X1GA 4D0NB 1X86A 1BWNA 2YT0A 2ZPYA 3FSSA 2BCJA 3HQCA 3TO1A 1DYNA 2IFSA 2J0KA 5L81A 3GYOA 4F7UP 1NU2A 4GMVA 2KCJA 2MFQA 3HW2B 3F5RA 1LW3A 2L2IA 2RNRB 2DN6A 2YT1A 4Y94A 2P0DA 2MDXA 5CLLB 1AWEA 4A6KA 1EAZA 1FGZA 1ZC3B 1IRSA 4DXAB 4H8SA 4MT7A 2DA0A 2FJLA 2HTHB 3AU5A 1U5EA 1PMSA 1NI2A 1RJ2A 2K00A 5C6RA 1OY2A 3KRWA 1UEFA 4DX8A 2DLWA 2CAYA 4B6HA 1V89A 2VSZA 5JP4A 4MY6A 3HK0A 3PP2A 5LOPB 1OQNA 1U5GA 3KY9A 4K17A 4GMXB 1QC6A 5EFXA 3KRXA 4GXBA 3N7CA 2DX1A 2COFA 2PZ1A 2W2WA 1PFJA 5DH9B 3BINA 2GS0A 2CODA 4Z2NA 2OTXA 3MPXA 4HAXB 2DHKA 5C79A 2Z0OA 1GG3A 2COCA 4HHVA 2DYQA 3GYPA 4HAZB 3AJ4A 2P8VA 1TXDA 4GZUA 2X18A 1GC6A 5DIFB 1X1FA 2E2XA 3D8DA 4K81A 2KUPA 5DHAB 1ZC4B 1EF1A 3ML4A 1B55A 1OMWA 2KGXB 4A6HA 2RVBB 1MPHA 2GJYA 2I5CA 1W1GA 2W2XC 1ZM0A 2Z0QA 1W1DA 4IAPA 1J0WA 2IYBA 3G9WA 2LOXA 1Q67A 3QWMA 2NZ8B 1H10A 1M7EA 1FGYA 1U2BA 3X23A 2RSGA 2D10A 3VOQA 1DDMA 3WYFB 1Y5OA 1UPQA 1J19A 2EMSA 2JP2A 1MIZB 1E5WA 2DHJA 2LOZA 1TJ6A 1X11A 3RCPA 1TQZA 3SV1A 1QQGA 2YS3A 2P0FA 3PVLA 2CY5A 4WVFB 5GOWB 1SHCA 2MKRA 4EJNA 5JLJB 1XR0B 4NSWA 3AU4A 4IOYX 2VRWB 2DKPA 4A5KA 1FOEA 4HAUB 2D9ZA 2R09A 1UNRA 1UNPA 3DXEA 2AEHA 1U5FA 5C5BA 1DDWA 4HB0B 4KHAA 3TW1A 4TKNA 1GC7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V76 A;  4PNK A;  2ROZ B;  4EMO A;  2K2U A;  1ISN A;  4YON A;  2J59 M;  1V88 A;  2UZR A;  1Z87 A;  1KZ7 A;  2OQB A;  1WJM A;  2LUL A;  1K5G B;  3SUZ A;  5FI0 A;  3PG7 A;  4CYE A;  1ZSQ A;  4KHB B;  2YS1 A;  4L6E A;  3P7Z A;  2Y8G A;  1U27 A;  2EC1 A;  3DXD A;  1M7R A;  2DTC A;  5D3X A;  1XD4 A;  5C5B B;  4KHO A;  1PLS A;  3ODX A;  4ZRI A;  4XWX A;  4K2P A;  2D2Q A;  4CHJ A;  4PQ0 A;  1DBH A;  4GN1 A;  1SGH A;  2RLO A;  2DX5 A;  1RRP B;  1WG7 A;  3LJU X;  2Y7B A;  1FHX A;  1WJ1 A;  2YVC A;  5D3Y A;  4GPT B;  3V5W A;  2RUK B;  2R0D A;  2GCJ A;  2MWN B;  4F7H A;  3PSC A;  2DKQ A;  1XOD A;  3P6A A;  4Z2M B;  1X05 A;  2L1C A;  1UPR A;  2N23 A;  5J3Y A;  1V61 A;  1FAO A;  1V5P A;  1FHW A;  5HE3 A;  3U8Z A;  2P0H A;  3BJI A;  4BBK A;  1BTN A;  2EMT A;  1KI1 B;  1XX0 A;  2LYD A;  5C16 A;  3O96 A;  1N3H A;  1MK9 B;  1I2H A;  3ULC A;  2UZS A;  3NSU A;  1MAI A;  4KVG B;  2D9Y A;  2XQN M;  1P6S A;  1EGX A;  3FM8 C;  3QBV B;  4TYZ A;  1FHO A;  4HAY B;  1V5M A;  2D9W A;  1K5D B;  5J3T A;  1U29 A;  4HB2 B;  2YF0 A;  5DHF B;  3DXC A;  3KSY A;  4K2O A;  3T06 A;  3FEH A;  2QKM A;  3TFM A;  3CIK A;  2H7E A;  4HAW B;  2K2J A;  2W2X D;  1W1H A;  3WA0 A;  4A6F A;  2YSZ A;  3U7D A;  2H7D A;  2J0J A;  2VKI A;  2Q13 A;  5HE2 A;  1WGU A;  3M1I B;  1Y19 B;  4CHM A;  1FB8 A;  3D8F A;  5D3V A;  3SO6 A;  2ADZ A;  2UVM A;  3ODW A;  1KZG A;  1BAK A;  4HB3 B;  3ZDT A;  2Z0P A;  4F7G A;  2GCL A;  2D9V A;  4ZRJ A;  1U5D A;  1AQC A;  2CRF A;  2EJ8 A;  1BTK A;  5KQ4 A;  3SNH A;  2HE7 A;  5D3W A;  4MK0 A;  1LB1 A;  5LON B;  2I1K A;  1DDV A;  2ROV A;  5KQ1 A;  2I1J A;  3A8Q A;  2D11 A;  2M38 A;  2ELB A;  2LKO A;  4HAT B;  5FI1 A;  4EKU A;  2DYN A;  2D4Q A;  4A6F B;  4DX9 0;  1P3R A;  2D9X A;  1EVH A;  2COA A;  2YS5 A;  1I7A A;  5CLQ B;  5DI9 B;  3TCA A;  1WVH A;  3SYX A;  2DHI A;  4C0A A;  5J3Q A;  5JHG A;  3A98 B;  1MKE A;  2CY4 A;  4P7I A;  2I5F A;  3D8E A;  2J0M A;  2DFK A;  5D27 A;  1H4R A;  5HE1 A;  2LG1 A;  4WSF A;  3ULB A;  3VIA A;  2M14 A;  3UZT A;  2ELA A;  4HB4 B;  1XKE A;  3QIJ A;  2QKL A;  1ZVR A;  5KCV A;  2AL6 A;  3OAN A;  2YRY A;  4HDO A;  1MIX A;  1NTY A;  4WJ7 A;  3TVV A;  3IVF A;  3CXB B;  2N0Y A;  3F0W A;  4NY0 A;  2NMB A;  1NTV A;  1MK7 B;  1WGQ A;  2RGN B;  2G35 A;  3PVW A;  3PEG A;  4HDQ A;  3PVU A;  4IFS A;  4HAV B;  5HE0 A;  4DBB A;  1V5U A;  1WI1 A;  1UNQ A;  3KZ1 A;  4ZRK A;  1P5T A;  3MDB C;  3ODO A;  1XCG A;  2Y8F A;  4YL8 A;  1DRO A;  3PZD A;  5JHH A;  3A8P A;  3ZVR A;  4KAX B;  1X1G A;  4D0N B;  1X86 A;  1BWN A;  2YT0 A;  2ZPY A;  3FSS A;  2BCJ A;  3HQC A;  3TO1 A;  1DYN A;  2IFS A;  2J0K A;  5L81 A;  3GYO A;  4F7U P;  1NU2 A;  4GMV A;  2KCJ A;  2MFQ A;  3HW2 B;  3F5R A;  1LW3 A;  2L2I A;  2RNR B;  2DN6 A;  2YT1 A;  4Y94 A;  2P0D A;  2MDX A;  5CLL B;  1AWE A;  4A6K A;  1EAZ A;  1FGZ A;  1ZC3 B;  1IRS A;  4DXA B;  4H8S A;  4MT7 A;  2DA0 A;  2FJL A;  2HTH B;  3AU5 A;  1U5E A;  1PMS A;  1NI2 A;  1RJ2 A;  2K00 A;  5C6R A;  1OY2 A;  3KRW A;  1UEF A;  4DX8 A;  2DLW A;  2CAY A;  4B6H A;  1V89 A;  2VSZ A;  5JP4 A;  4MY6 A;  3HK0 A;  3PP2 A;  5LOP B;  1OQN A;  1U5G A;  3KY9 A;  4K17 A;  4GMX B;  1QC6 A;  5EFX A;  3KRX A;  4GXB A;  3N7C A;  2DX1 A;  2COF A;  2PZ1 A;  2W2W A;  1PFJ A;  5DH9 B;  3BIN A;  2GS0 A;  2COD A;  4Z2N A;  2OTX A;  3MPX A;  4HAX B;  2DHK A;  5C79 A;  2Z0O A;  1GG3 A;  2COC A;  4HHV A;  2DYQ A;  3GYP A;  4HAZ B;  3AJ4 A;  2P8V A;  1TXD A;  4GZU A;  2X18 A;  1GC6 A;  5DIF B;  1X1F A;  2E2X A;  3D8D A;  4K81 A;  2KUP A;  5DHA B;  1ZC4 B;  1EF1 A;  3ML4 A;  1B55 A;  1OMW A;  2KGX B;  4A6H A;  2RVB B;  1MPH A;  2GJY A;  2I5C A;  1W1G A;  2W2X C;  1ZM0 A;  2Z0Q A;  1W1D A;  4IAP A;  1J0W A;  2IYB A;  3G9W A;  2LOX A;  1Q67 A;  3QWM A;  2NZ8 B;  1H10 A;  1M7E A;  1FGY A;  1U2B A;  3X23 A;  2RSG A;  2D10 A;  3VOQ A;  1DDM A;  3WYF B;  1Y5O A;  1UPQ A;  1J19 A;  2EMS A;  2JP2 A;  1MIZ B;  1E5W A;  2DHJ A;  2LOZ A;  1TJ6 A;  1X11 A;  3RCP A;  1TQZ A;  3SV1 A;  1QQG A;  2YS3 A;  2P0F A;  3PVL A;  2CY5 A;  4WVF B;  5GOW B;  1SHC A;  2MKR A;  4EJN A;  5JLJ B;  1XR0 B;  4NSW A;  3AU4 A;  4IOY X;  2VRW B;  2DKP A;  4A5K A;  1FOE A;  4HAU B;  2D9Z A;  2R09 A;  1UNR A;  1UNP A;  3DXE A;  2AEH A;  1U5F A;  5C5B A;  1DDW A;  4HB0 B;  4KHA A;  3TW1 A;  4TKN A;  1GC7 A; 
#chains in the Genus database with same CATH topology
 2V76 A;  4PNK A;  2ROZ B;  4EMO A;  2K2U A;  1ISN A;  4YON A;  2J59 M;  1V88 A;  2UZR A;  1Z87 A;  1KZ7 A;  2OQB A;  1WJM A;  2LUL A;  1K5G B;  3SUZ A;  5FI0 A;  3PG7 A;  2KR0 A;  4CYE A;  1ZSQ A;  2K8E A;  4KHB B;  2YS1 A;  4L6E A;  3P7Z A;  2Y8G A;  1U27 A;  2EC1 A;  3DXD A;  2KIE A;  1M7R A;  2DTC A;  5D3X A;  1XD4 A;  4GNK B;  3U12 A;  5C5B B;  4KHO A;  1PLS A;  3ODX A;  4ZRI A;  4XWX A;  4K2P A;  2D2Q A;  4CHJ A;  4PQ0 A;  1DBH A;  4GN1 A;  1SGH A;  2RLO A;  2DX5 A;  1RRP B;  1WG7 A;  3LJU X;  2Y7B A;  1FHX A;  1WJ1 A;  2YVC A;  3NWD A;  5D3Y A;  4GPT B;  3V5W A;  2RUK B;  2R0D A;  2GCJ A;  2MWN B;  4F7H A;  3PSC A;  2DKQ A;  1XOD A;  3P6A A;  4Z2M B;  1X05 A;  2L1C A;  1UPR A;  2N23 A;  5J3Y A;  1V61 A;  1FAO A;  1V5P A;  1FHW A;  5HE3 A;  3U8Z A;  2P0H A;  3BJI A;  4BBK A;  1BTN A;  2EMT A;  1KI1 B;  1XX0 A;  2LYD A;  5C16 A;  3O96 A;  1N3H A;  1MK9 B;  1I2H A;  3ULC A;  2UZS A;  3NSU A;  1MAI A;  4KVG B;  1MI1 A;  2D9Y A;  2XQN M;  4DIX A;  1P6S A;  1EGX A;  3FM8 C;  3QBV B;  4TYZ A;  1FHO A;  4HAY B;  1V5M A;  2D9W A;  1K5D B;  5J3T A;  1U29 A;  4HB2 B;  2YF0 A;  5DHF B;  3DXC A;  3KSY A;  4K2O A;  3T06 A;  3FEH A;  2QKM A;  3TFM A;  3CIK A;  4QJ3 B;  2H7E A;  4HAW B;  2K2J A;  5M4Y B;  2W2X D;  1W1H A;  3WA0 A;  4A6F A;  2YSZ A;  3U7D A;  2H7D A;  2J0J A;  2VKI A;  2Q13 A;  2NBV A;  5HE2 A;  1WGU A;  3M1I B;  1Y19 B;  4CHM A;  1FB8 A;  3D8F A;  5D3V A;  3SO6 A;  2FJU B;  2ADZ A;  2UVM A;  2Z59 A;  3ODW A;  1KZG A;  1BAK A;  4HB3 B;  3ZDT A;  2Z0P A;  4F7G A;  2GCL A;  2D9V A;  4ZRJ A;  1U5D A;  1AQC A;  2CRF A;  2EJ8 A;  3NW8 A;  1BTK A;  5KQ4 A;  3SNH A;  2HE7 A;  5D3W A;  4MK0 A;  1LB1 A;  5LON B;  2I1K A;  1DDV A;  2ROV A;  5KQ1 A;  2I1J A;  3A8Q A;  2D11 A;  2M38 A;  2ELB A;  2LKO A;  4HAT B;  5FI1 A;  4EKU A;  2DYN A;  2D4Q A;  3B77 A;  4A6F B;  4DX9 0;  1P3R A;  2D9X A;  1EVH A;  2COA A;  2YS5 A;  1I7A A;  5CLQ B;  5DI9 B;  3TCA A;  1WVH A;  3SYX A;  2DHI A;  4C0A A;  5J3Q A;  5JHG A;  3A98 B;  1MKE A;  3NWA A;  2GUM A;  2CY4 A;  4P7I A;  2I5F A;  3D8E A;  2J0M A;  2DFK A;  5D27 A;  2Z13 A;  1H4R A;  5HE1 A;  2LG1 A;  4WSF A;  3ULB A;  3VIA A;  2M14 A;  3UZT A;  2ELA A;  4HB4 B;  1XKE A;  3QIJ A;  2QKL A;  1ZVR A;  3OHM B;  2AL6 A;  5KCV A;  2R2Y A;  2RRF A;  3OAN A;  4QXA B;  2YRY A;  5IRS A;  4OT1 A;  4HDO A;  1MIX A;  1NTY A;  4WJ7 A;  3TVV A;  3IVF A;  3CXB B;  2Z14 A;  2N0Y A;  3F0W A;  4NY0 A;  2NMB A;  1NTV A;  1MK7 B;  1WGQ A;  2RGN B;  2G35 A;  3PVW A;  3PEG A;  4HDQ A;  3PVU A;  4IFS A;  4HAV B;  5HE0 A;  4DBB A;  1V5U A;  1WI1 A;  1UNQ A;  2ZKM X;  3KZ1 A;  4ZRK A;  1P5T A;  3MDB C;  3ODO A;  1XCG A;  2Y8F A;  4YL8 A;  1DRO A;  3PZD A;  5JHH A;  3A8P A;  3ZVR A;  4KAX B;  1X1G A;  4D0N B;  1X86 A;  1BWN A;  2YT0 A;  2ZPY A;  3FSS A;  4L1R A;  2BCJ A;  3HQC A;  3TO1 A;  3FVC A;  1DYN A;  2IFS A;  2J0K A;  1T77 A;  5L81 A;  1ZYI A;  3GYO A;  4F7U P;  1NU2 A;  4GMV A;  2KCJ A;  2MFQ A;  3HW2 B;  3F5R A;  1LW3 A;  2L2I A;  2RNR B;  2DN6 A;  2YT1 A;  4Y94 A;  2P0D A;  2MDX A;  5CLL B;  1AWE A;  4A6K A;  1EAZ A;  1FGZ A;  1ZC3 B;  1IRS A;  4DXA B;  4H8S A;  2KIG A;  2DA0 A;  4MT7 A;  2FJL A;  2HTH B;  3AU5 A;  1U5E A;  1PMS A;  1NI2 A;  1RJ2 A;  2K00 A;  5C6R A;  1OY2 A;  3KRW A;  1UEF A;  4DX8 A;  2DLW A;  2CAY A;  4GOU A;  2Z4D A;  4QJ5 B;  4B6H A;  1V89 A;  3NWF A;  2VSZ A;  5JP4 A;  5I2M A;  4MY6 A;  3A58 A;  3HK0 A;  3PP2 A;  3HSA A;  5LOP B;  1OQN A;  5LG4 B;  1U5G A;  3KY9 A;  3DCX A;  4K17 A;  4GMX B;  1QC6 A;  5EFX A;  3KRX A;  4GXB A;  3N7C A;  2DX1 A;  2COF A;  2PZ1 A;  2W2W A;  1PFJ A;  5DH9 B;  3HIE A;  3BIN A;  2GS0 A;  2COD A;  4Z2N A;  2OTX A;  3MPX A;  4HAX B;  2DHK A;  5C79 A;  2Z0O A;  2YT2 A;  1GG3 A;  2COC A;  4QJ4 B;  4HHV A;  2DYQ A;  3GYP A;  4HAZ B;  3AJ4 A;  2P8V A;  1TXD A;  4GZU A;  2X18 A;  1GC6 A;  5DIF B;  1X1F A;  2E2X A;  4D6W A;  3D8D A;  4K81 A;  2KUP A;  5DHA B;  1ZC4 B;  1EF1 A;  3ML4 A;  1B55 A;  1OMW A;  2KGX B;  4A6H A;  2RVB B;  1MPH A;  2GJY A;  2I5C A;  1W1G A;  2W2X C;  1ZM0 A;  2Z0Q A;  1W1D A;  4IAP A;  1J0W A;  2IYB A;  3G9W A;  2LOX A;  4HSI A;  1Q67 A;  3QWM A;  2NZ8 B;  1H10 A;  4OSN A;  1M7E A;  1FGY A;  1U2B A;  3X23 A;  2RSG A;  2D10 A;  3VOQ A;  1DDM A;  3WYF B;  1Y5O A;  1UPQ A;  1J19 A;  2EMS A;  2JP2 A;  1MIZ B;  1E5W A;  2DHJ A;  2LOZ A;  1TJ6 A;  1X11 A;  3RCP A;  2KUQ A;  1TQZ A;  3SV1 A;  1QQG A;  2YS3 A;  2P0F A;  3PVL A;  2CY5 A;  2K49 A;  4WVF B;  5GOW B;  1SHC A;  2MKR A;  4EJN A;  5JLJ B;  1XR0 B;  4NSW A;  3AU4 A;  4KHB A;  4IOY X;  2VRW B;  2DKP A;  4A5K A;  5I2S A;  1FOE A;  4HAU B;  4CSQ A;  2D9Z A;  2R09 A;  1UNR A;  1UNP A;  3DXE A;  2AEH A;  1U5F A;  5C5B A;  1DDW A;  4HB0 B;  4KHA A;  3TW1 A;  4TKN A;  1GC7 A; 
#chains in the Genus database with same CATH homology
 2V76 A;  4PNK A;  2ROZ B;  4EMO A;  2K2U A;  1ISN A;  4YON A;  2J59 M;  1V88 A;  2UZR A;  1Z87 A;  1KZ7 A;  2OQB A;  1WJM A;  2LUL A;  1K5G B;  3SUZ A;  5FI0 A;  3PG7 A;  4CYE A;  1ZSQ A;  4KHB B;  2YS1 A;  4L6E A;  3P7Z A;  2Y8G A;  1U27 A;  2EC1 A;  3DXD A;  1M7R A;  2DTC A;  5D3X A;  1XD4 A;  5C5B B;  4KHO A;  1PLS A;  3ODX A;  4ZRI A;  4XWX A;  4K2P A;  2D2Q A;  4CHJ A;  4PQ0 A;  1DBH A;  4GN1 A;  1SGH A;  2RLO A;  2DX5 A;  1RRP B;  1WG7 A;  3LJU X;  2Y7B A;  1FHX A;  1WJ1 A;  2YVC A;  5D3Y A;  4GPT B;  3V5W A;  2RUK B;  2R0D A;  2GCJ A;  2MWN B;  4F7H A;  3PSC A;  2DKQ A;  1XOD A;  3P6A A;  4Z2M B;  1X05 A;  2L1C A;  1UPR A;  2N23 A;  5J3Y A;  1V61 A;  1FAO A;  1V5P A;  1FHW A;  5HE3 A;  3U8Z A;  2P0H A;  3BJI A;  4BBK A;  1BTN A;  2EMT A;  1KI1 B;  1XX0 A;  2LYD A;  5C16 A;  3O96 A;  1N3H A;  1MK9 B;  1I2H A;  3ULC A;  2UZS A;  3NSU A;  1MAI A;  4KVG B;  2D9Y A;  2XQN M;  1P6S A;  1EGX A;  3FM8 C;  3QBV B;  4TYZ A;  1FHO A;  4HAY B;  1V5M A;  2D9W A;  1K5D B;  5J3T A;  1U29 A;  4HB2 B;  2YF0 A;  5DHF B;  3DXC A;  3KSY A;  4K2O A;  3T06 A;  3FEH A;  2QKM A;  3TFM A;  3CIK A;  2H7E A;  4HAW B;  2K2J A;  2W2X D;  1W1H A;  3WA0 A;  4A6F A;  2YSZ A;  3U7D A;  2H7D A;  2J0J A;  2VKI A;  2Q13 A;  5HE2 A;  1WGU A;  3M1I B;  1Y19 B;  4CHM A;  1FB8 A;  3D8F A;  5D3V A;  3SO6 A;  2ADZ A;  2UVM A;  3ODW A;  1KZG A;  1BAK A;  4HB3 B;  3ZDT A;  2Z0P A;  4F7G A;  2GCL A;  2D9V A;  4ZRJ A;  1U5D A;  1AQC A;  2CRF A;  2EJ8 A;  1BTK A;  5KQ4 A;  3SNH A;  2HE7 A;  5D3W A;  4MK0 A;  1LB1 A;  5LON B;  2I1K A;  1DDV A;  2ROV A;  5KQ1 A;  2I1J A;  3A8Q A;  2D11 A;  2M38 A;  2ELB A;  2LKO A;  4HAT B;  5FI1 A;  4EKU A;  2DYN A;  2D4Q A;  4A6F B;  4DX9 0;  1P3R A;  2D9X A;  1EVH A;  2COA A;  2YS5 A;  1I7A A;  5CLQ B;  5DI9 B;  3TCA A;  1WVH A;  3SYX A;  2DHI A;  4C0A A;  5J3Q A;  5JHG A;  3A98 B;  1MKE A;  2CY4 A;  4P7I A;  2I5F A;  3D8E A;  2J0M A;  2DFK A;  5D27 A;  1H4R A;  5HE1 A;  2LG1 A;  4WSF A;  3ULB A;  3VIA A;  2M14 A;  3UZT A;  2ELA A;  4HB4 B;  1XKE A;  3QIJ A;  2QKL A;  1ZVR A;  5KCV A;  2AL6 A;  3OAN A;  2YRY A;  4HDO A;  1MIX A;  1NTY A;  4WJ7 A;  3TVV A;  3IVF A;  3CXB B;  2N0Y A;  3F0W A;  4NY0 A;  2NMB A;  1NTV A;  1MK7 B;  1WGQ A;  2RGN B;  2G35 A;  3PVW A;  3PEG A;  4HDQ A;  3PVU A;  4IFS A;  4HAV B;  5HE0 A;  4DBB A;  1V5U A;  1WI1 A;  1UNQ A;  3KZ1 A;  4ZRK A;  1P5T A;  3MDB C;  3ODO A;  1XCG A;  2Y8F A;  4YL8 A;  1DRO A;  3PZD A;  5JHH A;  3A8P A;  3ZVR A;  4KAX B;  1X1G A;  4D0N B;  1X86 A;  1BWN A;  2YT0 A;  2ZPY A;  3FSS A;  2BCJ A;  3HQC A;  3TO1 A;  1DYN A;  2IFS A;  2J0K A;  5L81 A;  3GYO A;  4F7U P;  1NU2 A;  4GMV A;  2KCJ A;  2MFQ A;  3HW2 B;  3F5R A;  1LW3 A;  2L2I A;  2RNR B;  2DN6 A;  2YT1 A;  4Y94 A;  2P0D A;  2MDX A;  5CLL B;  1AWE A;  4A6K A;  1EAZ A;  1FGZ A;  1ZC3 B;  1IRS A;  4DXA B;  4H8S A;  4MT7 A;  2DA0 A;  2FJL A;  2HTH B;  3AU5 A;  1U5E A;  1PMS A;  1NI2 A;  1RJ2 A;  2K00 A;  5C6R A;  1OY2 A;  3KRW A;  1UEF A;  4DX8 A;  2DLW A;  2CAY A;  4B6H A;  1V89 A;  2VSZ A;  5JP4 A;  4MY6 A;  3HK0 A;  3PP2 A;  5LOP B;  1OQN A;  1U5G A;  3KY9 A;  4K17 A;  4GMX B;  1QC6 A;  5EFX A;  3KRX A;  4GXB A;  3N7C A;  2DX1 A;  2COF A;  2PZ1 A;  2W2W A;  1PFJ A;  5DH9 B;  3BIN A;  2GS0 A;  2COD A;  4Z2N A;  2OTX A;  3MPX A;  4HAX B;  2DHK A;  5C79 A;  2Z0O A;  1GG3 A;  2COC A;  4HHV A;  2DYQ A;  3GYP A;  4HAZ B;  3AJ4 A;  2P8V A;  1TXD A;  4GZU A;  2X18 A;  1GC6 A;  5DIF B;  1X1F A;  2E2X A;  3D8D A;  4K81 A;  2KUP A;  5DHA B;  1ZC4 B;  1EF1 A;  3ML4 A;  1B55 A;  1OMW A;  2KGX B;  4A6H A;  2RVB B;  1MPH A;  2GJY A;  2I5C A;  1W1G A;  2W2X C;  1ZM0 A;  2Z0Q A;  1W1D A;  4IAP A;  1J0W A;  2IYB A;  3G9W A;  2LOX A;  1Q67 A;  3QWM A;  2NZ8 B;  1H10 A;  1M7E A;  1FGY A;  1U2B A;  3X23 A;  2RSG A;  2D10 A;  3VOQ A;  1DDM A;  3WYF B;  1Y5O A;  1UPQ A;  1J19 A;  2EMS A;  2JP2 A;  1MIZ B;  1E5W A;  2DHJ A;  2LOZ A;  1TJ6 A;  1X11 A;  3RCP A;  1TQZ A;  3SV1 A;  1QQG A;  2YS3 A;  2P0F A;  3PVL A;  2CY5 A;  4WVF B;  5GOW B;  1SHC A;  2MKR A;  4EJN A;  5JLJ B;  1XR0 B;  4NSW A;  3AU4 A;  4IOY X;  2VRW B;  2DKP A;  4A5K A;  1FOE A;  4HAU B;  2D9Z A;  2R09 A;  1UNR A;  1UNP A;  3DXE A;  2AEH A;  1U5F A;  5C5B A;  1DDW A;  4HB0 B;  4KHA A;  3TW1 A;  4TKN A;  1GC7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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