1BTKA

Ph domain and btk motif from bruton's tyrosine kinase mutant r28c
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
169
structure length
160
Chain Sequence
AAVILESIFLKRSQQKKKTSPLNFKKCLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILEN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemia.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords BRUTON'S TYROSINE KINASE
total genus 33
structure length 160
sequence length 169
chains with identical sequence B
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 1997-07-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF00779 BTK BTK motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1btkA00
2GCLA 4B6HA 4HATB 2FJLA 2QKMA 3LJUX 2X18A 5C5BA 2L2IA 3CIKA 2Y7BA 2YT1A 5D3XA 1V88A 3ML4A 3SO6A 1MAIA 1Y5OA 4BBKA 3PVUA 5HE3A 2LOXA 2J59M 4KVGB 2P0FA 3D8FA 5DHFB 1DBHA 2D4QA 4YONA 1J0WA 1IRSA 2D9WA 5FI0A 1XR0B 1V61A 2JP2A 1NTVA 5C5BB 2DHIA 2DKPA 1AWEA 2D9YA 4HAWB 2L1CA 2ROZB 4HAVB 2LULA 1BTNA 3SV1A 2YSZA 2XQNM 3F5RA 1V5MA 1UPQA 2J0MA 1N3HA 2CY5A 2R0DA 4HAUB 4IAPA 3ULCA 3P7ZA 2DHKA 2EMTA 2DX1A 4EJNA 2DN6A 3PZDA 3ZDTA 3ODOA 1H10A 1NU2A 1QC6A 2VKIA 1X11A 5D3VA 2CAYA 2UZRA 4HDQA 2D2QA 3TCAA 4EKUA 5EFXA 2E2XA 5DHAB 1P3RA 1FOEA 3ODXA 1BWNA 1PLSA 2W2WA 1AQCA 1ZC4B 1KZGA 4ZRIA 5HE0A 2ELBA 3KRWA 2I1JA 1WGQA 2MDXA 1U5FA 5JHGA 2K00A 1XX0A 4P7IA 1EGXA 1TJ6A 3WA0A 1SGHA 2NZ8B 2ADZA 4HHVA 1U29A 1X05A 4DBBA 3UZTA 5JP4A 4C0AA 1LW3A 3TO1A 3U8ZA 4PNKA 5JLJB 4HB4B 4A6KA 4NY0A 4KHBB 2ELAA 4EMOA 2OTXA 2MKRA 5D27A 2DX5A 3HW2B 1P6SA 1FB8A 2EC1A 3KY9A 1FGYA 3ULBA 2ROVA 4L6EA 4A6HA 4DX8A 1DROA 3BJIA 2Z0QA 2RSGA 1EVHA 1PMSA 4DXAB 1ZC3B 2I1KA 1M7RA 2IFSA 2DKQA 4GXBA 1FHWA 3DXDA 2P8VA 2LKOA 1H4RA 1WVHA 1U5EA 1B55A 4MT7A 1W1DA 2CRFA 3PEGA 1I7AA 2OQBA 2ZPYA 3ODWA 3QBVB 2UVMA 2COCA 1DDMA 2D9ZA 2CODA 2N0YA 2W2XD 1U27A 1WGUA 4K17A 1OY2A 5HE2A 2YVCA 3DXEA 2DHJA 1WJ1A 1FAOA 4HAXB 4HDOA 3SNHA 2YF0A 4YL8A 1W1HA 3VIAA 2LYDA 4WJ7A 1ZM0A 4WVFB 1OQNA 4KHOA 2J0JA 3X23A 1EAZA 1MK7B 4GN1A 3PG7A 2YS5A 1BAKA 1UNQA 3MPXA 1KZ7A 2K2UA 4F7HA 3CXBB 2K2JA 1TQZA 3FSSA 1ISNA 1K5GB 4TKNA 2V76A 1J19A 5J3QA 1I2HA 1MKEA 1MK9B 2LOZA 4MK0A 5LOPB 3D8EA 2Z0PA 1RJ2A 1MPHA 4HB3B 1XKEA 2MWNB 3P6AA 2RVBB 2RUKB 2Q13A 1V89A 2YRYA 1ZSQA 1Q67A 2EJ8A 1UPRA 3BINA 4Z2NA 4IOYX 4MY6A 5KQ4A 1U5GA 1EF1A 3A8PA 3OANA 2D9VA 4GMVA 2KGXB 1MIXA 2DLWA 5D3WA 4ZRKA 2H7DA 3WYFB 2M38A 4K2OA 3AU5A 2I5FA 3VOQA 3KRXA 4GZUA 5C79A 3PVLA 3TW1A 2RNRB 3FM8C 4DX90 1WI1A 4XWXA 4HAYB 2GCJA 2QKLA 1E5WA 2PZ1A 2UZSA 3HK0A 1X1FA 4H8SA 4F7GA 2AL6A 1LB1A 3NSUA 5J3YA 2AEHA 4IFSA 4K2PA 4WSFA 2G35A 4TYZA 3SUZA 1QQGA 4HB2B 1XODA 3TVVA 3A8QA 1FHXA 2D11A 3ZVRA 1BTKA 5DH9B 4KHAA 3V5WA 1FGZA 2P0HA 2CY4A 1U5DA 3N7CA 1KI1B 3A98B 2D9XA 1X1GA 4KAXB 5CLQB 1V5UA 2Z0OA 5C6RA 2D10A 2RLOA 4ZRJA 2P0DA 2DFKA 1Y19B 3PP2A 1Z87A 3QIJA 4A6FA 4CYEA 3O96A 3QWMA 2COFA 4F7UP 2RGNB 2DYQA 5CLLB 2Y8FA 3TFMA 3KSYA 2YT0A 3HQCA 1X86A 1UNRA 3F0WA 3MDBC 1WJMA 2GJYA 2YS1A 3IVFA 4D0NB 4CHMA 3GYOA 2N23A 1MIZB 5C16A 5KQ1A 2DA0A 4Z2MB 4HAZB 4GPTB 2Y8GA 4A6FB 3PSCA 1K5DB 3G9WA 1TXDA 5LONB 1RRPB 2NMBA 2HE7A 3AU4A 2COAA 1DDVA 2HTHB 5L81A 4NSWA 1NI2A 4PQ0A 2I5CA 2M14A 1DYNA 5DIFB 2VSZA 1GC6A 3SYXA 2IYBA 2KUPA 1ZVRA 1PFJA 1GC7A 3AJ4A 1P5TA 2MFQA 1WG7A 2J0KA 3KZ1A 3GYPA 5J3TA 5DI9B 1XCGA 4K81A 1M7EA 4HB0B 5HE1A 2YS3A 5FI1A 2KCJA 3PVWA 1OMWA 4GMXB 1XD4A 4CHJA 1NTYA 3T06A 1U2BA 2W2XC 1SHCA 5GOWB 1GG3A 2LG1A 3D8DA 3FEHA 2EMSA 5KCVA 2DYNA 2DTCA 4Y94A 1W1GA 2R09A 3M1IB 1DDWA 3DXCA 1UNPA 5JHHA 2BCJA 1UEFA 2VRWB 3U7DA 2GS0A 1FHOA 4A5KA 3RCPA 5D3YA 1V5PA 2H7EA
chains in the Genus database with same CATH superfamily
2GCLA 4B6HA 4HATB 2FJLA 2QKMA 3LJUX 2X18A 5C5BA 2KUQA 2L2IA 3CIKA 2Y7BA 2YT1A 5D3XA 1V88A 3ML4A 3SO6A 1MAIA 2FJUB 1Y5OA 4BBKA 3PVUA 5HE3A 2LOXA 2J59M 4KVGB 2P0FA 3D8FA 5DHFB 1DBHA 2D4QA 4YONA 1J0WA 1IRSA 2D9WA 5FI0A 1XR0B 2Z14A 1V61A 2JP2A 1NTVA 5C5BB 2DHIA 3U12A 2DKPA 1AWEA 2D9YA 4HAWB 2L1CA 2ROZB 4HAVB 2LULA 1BTNA 3SV1A 2YSZA 2XQNM 3F5RA 1V5MA 1UPQA 2J0MA 1N3HA 2CY5A 2R0DA 4HAUB 4IAPA 3ULCA 5I2MA 3P7ZA 2DHKA 2EMTA 2DX1A 4EJNA 2DN6A 3PZDA 3ZDTA 5IRSA 2YT2A 3ODOA 1H10A 1NU2A 1QC6A 2VKIA 1X11A 5D3VA 2CAYA 2UZRA 4HDQA 2D2QA 4GNKB 3TCAA 4EKUA 3DCXA 5EFXA 2E2XA 5DHAB 2RRFA 1P3RA 1FOEA 3ODXA 1BWNA 1PLSA 2W2WA 4DIXA 1AQCA 1ZC4B 2R2YA 1KZGA 4ZRIA 5HE0A 2ELBA 3KRWA 2I1JA 1WGQA 2MDXA 1U5FA 5JHGA 2K00A 4KHBA 1XX0A 3HSAA 4P7IA 1EGXA 1TJ6A 4HSIA 3WA0A 1SGHA 2NZ8B 2ADZA 4HHVA 1U29A 1X05A 4OT1A 4DBBA 3UZTA 4QXAB 5JP4A 4CSQA 4C0AA 1LW3A 3TO1A 3U8ZA 4L1RA 4PNKA 3HIEA 5JLJB 4HB4B 4A6KA 3NW8A 4NY0A 4KHBB 2ELAA 4EMOA 2OTXA 2MKRA 5D27A 2DX5A 3HW2B 1P6SA 1FB8A 2EC1A 3KY9A 1FGYA 3ULBA 2ROVA 4L6EA 4A6HA 4DX8A 1DROA 3BJIA 2Z0QA 2RSGA 1EVHA 1PMSA 4DXAB 1ZC3B 2I1KA 1M7RA 2IFSA 2DKQA 3A58A 4GXBA 1FHWA 3DXDA 2P8VA 3NWDA 2LKOA 1H4RA 1WVHA 1U5EA 1B55A 4MT7A 1W1DA 2CRFA 2GUMA 3PEGA 1I7AA 2OQBA 2ZPYA 3ODWA 3QBVB 2UVMA 2COCA 1DDMA 2D9ZA 2CODA 2N0YA 2W2XD 1U27A 1WGUA 4K17A 1OY2A 5HE2A 2YVCA 1MI1A 1T77A 3DXEA 2DHJA 1WJ1A 1FAOA 4HAXB 4HDOA 3SNHA 2YF0A 4YL8A 1W1HA 3VIAA 5LG4B 2LYDA 4WJ7A 2KIGA 1ZM0A 4WVFB 1OQNA 4KHOA 2J0JA 3X23A 1EAZA 5M4YB 1MK7B 4GN1A 3PG7A 3OHMB 2YS5A 1BAKA 1UNQA 2K2UA 1KZ7A 3MPXA 4F7HA 3CXBB 2K2JA 1TQZA 3FSSA 1ISNA 1K5GB 4QJ5B 4TKNA 2V76A 4GOUA 1J19A 5J3QA 1I2HA 1MKEA 1MK9B 2LOZA 4MK0A 2KIEA 5LOPB 4QJ3B 3D8EA 2Z0PA 1RJ2A 1MPHA 4HB3B 1XKEA 2MWNB 3P6AA 2RVBB 2RUKB 2Q13A 1V89A 2YRYA 2KR0A 1ZSQA 1Q67A 2EJ8A 1UPRA 3BINA 4Z2NA 4IOYX 4MY6A 5KQ4A 1U5GA 1EF1A 3A8PA 3OANA 2D9VA 2Z59A 4GMVA 2KGXB 1MIXA 2DLWA 5D3WA 4ZRKA 2H7DA 3WYFB 2M38A 4K2OA 3AU5A 2K8EA 2I5FA 3VOQA 3KRXA 4GZUA 5C79A 3PVLA 3TW1A 2RNRB 3FM8C 4DX90 1WI1A 4XWXA 4HAYB 2GCJA 2QKLA 1E5WA 2PZ1A 2UZSA 3HK0A 2Z13A 1X1FA 4H8SA 4F7GA 2AL6A 1LB1A 3NSUA 5J3YA 2AEHA 4IFSA 4K2PA 4WSFA 2G35A 4TYZA 3SUZA 1QQGA 4HB2B 1XODA 3TVVA 3A8QA 3FVCA 2ZKMX 1FHXA 2D11A 3ZVRA 1BTKA 5DH9B 4KHAA 3V5WA 1FGZA 2P0HA 2CY4A 1U5DA 3N7CA 1KI1B 3A98B 2D9XA 1X1GA 4KAXB 5CLQB 1V5UA 2Z0OA 2NBVA 2D10A 2RLOA 5C6RA 4ZRJA 2P0DA 2DFKA 1Y19B 3PP2A 1Z87A 3QIJA 4A6FA 4CYEA 3O96A 3QWMA 2COFA 4F7UP 2RGNB 2DYQA 5CLLB 2Y8FA 3TFMA 3KSYA 2YT0A 3HQCA 1X86A 1UNRA 3F0WA 3MDBC 4QJ4B 1WJMA 2GJYA 2YS1A 3IVFA 4D0NB 4CHMA 3GYOA 2N23A 1MIZB 5C16A 5KQ1A 2DA0A 4Z2MB 4HAZB 4GPTB 2Y8GA 4A6FB 3PSCA 1K5DB 3G9WA 1TXDA 5LONB 1RRPB 2NMBA 2HE7A 3AU4A 2COAA 1DDVA 3NWAA 2HTHB 4D6WA 5L81A 4NSWA 1NI2A 4PQ0A 2I5CA 2M14A 1DYNA 5DIFB 2VSZA 1GC6A 3B77A 3SYXA 2IYBA 2KUPA 1ZVRA 1PFJA 1GC7A 3AJ4A 1P5TA 2MFQA 1WG7A 2J0KA 3KZ1A 3GYPA 5J3TA 5I2SA 5DI9B 1XCGA 3NWFA 4K81A 1M7EA 4HB0B 5HE1A 2YS3A 5FI1A 2K49A 2KCJA 1ZYIA 3PVWA 4OSNA 1OMWA 4GMXB 1XD4A 4CHJA 1NTYA 3T06A 1U2BA 2Z4DA 2W2XC 1SHCA 5GOWB 1GG3A 2LG1A 3D8DA 3FEHA 2EMSA 5KCVA 2DYNA 2DTCA 4Y94A 1W1GA 2R09A 3M1IB 1DDWA 3DXCA 1UNPA 5JHHA 2BCJA 1UEFA 2VRWB 3U7DA 2GS0A 1FHOA 4A5KA 3RCPA 5D3YA 1V5PA 2H7EA
chains in the Genus database with same CATH topology
2GCLA 4B6HA 4HATB 2FJLA 2QKMA 3LJUX 2X18A 5C5BA 2L2IA 3CIKA 2Y7BA 2YT1A 5D3XA 1V88A 3ML4A 3SO6A 1MAIA 1Y5OA 4BBKA 3PVUA 5HE3A 2LOXA 2J59M 4KVGB 2P0FA 3D8FA 5DHFB 1DBHA 2D4QA 4YONA 1J0WA 1IRSA 2D9WA 5FI0A 1XR0B 1V61A 2JP2A 1NTVA 5C5BB 2DHIA 2DKPA 1AWEA 2D9YA 4HAWB 2L1CA 2ROZB 4HAVB 2LULA 1BTNA 3SV1A 2YSZA 2XQNM 3F5RA 1V5MA 1UPQA 2J0MA 1N3HA 2CY5A 2R0DA 4HAUB 4IAPA 3ULCA 3P7ZA 2DHKA 2EMTA 2DX1A 4EJNA 2DN6A 3PZDA 3ZDTA 3ODOA 1H10A 1NU2A 1QC6A 2VKIA 1X11A 5D3VA 2CAYA 2UZRA 4HDQA 2D2QA 3TCAA 4EKUA 5EFXA 2E2XA 5DHAB 1P3RA 1FOEA 3ODXA 1BWNA 1PLSA 2W2WA 1AQCA 1ZC4B 1KZGA 4ZRIA 5HE0A 2ELBA 3KRWA 2I1JA 1WGQA 2MDXA 1U5FA 5JHGA 2K00A 1XX0A 4P7IA 1EGXA 1TJ6A 3WA0A 1SGHA 2NZ8B 2ADZA 4HHVA 1U29A 1X05A 4DBBA 3UZTA 5JP4A 4C0AA 1LW3A 3TO1A 3U8ZA 4PNKA 5JLJB 4HB4B 4A6KA 4NY0A 4KHBB 2ELAA 4EMOA 2OTXA 2MKRA 5D27A 2DX5A 3HW2B 1P6SA 1FB8A 2EC1A 3KY9A 1FGYA 3ULBA 2ROVA 4L6EA 4A6HA 4DX8A 1DROA 3BJIA 2Z0QA 2RSGA 1EVHA 1PMSA 4DXAB 1ZC3B 2I1KA 1M7RA 2IFSA 2DKQA 4GXBA 1FHWA 3DXDA 2P8VA 2LKOA 1H4RA 1WVHA 1U5EA 1B55A 4MT7A 1W1DA 2CRFA 3PEGA 1I7AA 2OQBA 2ZPYA 3ODWA 3QBVB 2UVMA 2COCA 1DDMA 2D9ZA 2CODA 2N0YA 2W2XD 1U27A 1WGUA 4K17A 1OY2A 5HE2A 2YVCA 3DXEA 2DHJA 1WJ1A 1FAOA 4HAXB 4HDOA 3SNHA 2YF0A 4YL8A 1W1HA 3VIAA 2LYDA 4WJ7A 1ZM0A 4WVFB 1OQNA 4KHOA 2J0JA 3X23A 1EAZA 1MK7B 4GN1A 3PG7A 2YS5A 1BAKA 1UNQA 3MPXA 1KZ7A 2K2UA 4F7HA 3CXBB 2K2JA 1TQZA 3FSSA 1ISNA 1K5GB 4TKNA 2V76A 1J19A 5J3QA 1I2HA 1MKEA 1MK9B 2LOZA 4MK0A 5LOPB 3D8EA 2Z0PA 1RJ2A 1MPHA 4HB3B 1XKEA 2MWNB 3P6AA 2RVBB 2RUKB 2Q13A 1V89A 2YRYA 1ZSQA 1Q67A 2EJ8A 1UPRA 3BINA 4Z2NA 4IOYX 4MY6A 5KQ4A 1U5GA 1EF1A 3A8PA 3OANA 2D9VA 4GMVA 2KGXB 1MIXA 2DLWA 5D3WA 4ZRKA 2H7DA 3WYFB 2M38A 4K2OA 3AU5A 2I5FA 3VOQA 3KRXA 4GZUA 5C79A 3PVLA 3TW1A 2RNRB 3FM8C 4DX90 1WI1A 4XWXA 4HAYB 2GCJA 2QKLA 1E5WA 2PZ1A 2UZSA 3HK0A 1X1FA 4H8SA 4F7GA 2AL6A 1LB1A 3NSUA 5J3YA 2AEHA 4IFSA 4K2PA 4WSFA 2G35A 4TYZA 3SUZA 1QQGA 4HB2B 1XODA 3TVVA 3A8QA 1FHXA 2D11A 3ZVRA 1BTKA 5DH9B 4KHAA 3V5WA 1FGZA 2P0HA 2CY4A 1U5DA 3N7CA 1KI1B 3A98B 2D9XA 1X1GA 4KAXB 5CLQB 1V5UA 2Z0OA 5C6RA 2D10A 2RLOA 4ZRJA 2P0DA 2DFKA 1Y19B 3PP2A 1Z87A 3QIJA 4A6FA 4CYEA 3O96A 3QWMA 2COFA 4F7UP 2RGNB 2DYQA 5CLLB 2Y8FA 3TFMA 3KSYA 2YT0A 3HQCA 1X86A 1UNRA 3F0WA 3MDBC 1WJMA 2GJYA 2YS1A 3IVFA 4D0NB 4CHMA 3GYOA 2N23A 1MIZB 5C16A 5KQ1A 2DA0A 4Z2MB 4HAZB 4GPTB 2Y8GA 4A6FB 3PSCA 1K5DB 3G9WA 1TXDA 5LONB 1RRPB 2NMBA 2HE7A 3AU4A 2COAA 1DDVA 2HTHB 5L81A 4NSWA 1NI2A 4PQ0A 2I5CA 2M14A 1DYNA 5DIFB 2VSZA 1GC6A 3SYXA 2IYBA 2KUPA 1ZVRA 1PFJA 1GC7A 3AJ4A 1P5TA 2MFQA 1WG7A 2J0KA 3KZ1A 3GYPA 5J3TA 5DI9B 1XCGA 4K81A 1M7EA 4HB0B 5HE1A 2YS3A 5FI1A 2KCJA 3PVWA 1OMWA 4GMXB 1XD4A 4CHJA 1NTYA 3T06A 1U2BA 2W2XC 1SHCA 5GOWB 1GG3A 2LG1A 3D8DA 3FEHA 2EMSA 5KCVA 2DYNA 2DTCA 4Y94A 1W1GA 2R09A 3M1IB 1DDWA 3DXCA 1UNPA 5JHHA 2BCJA 1UEFA 2VRWB 3U7DA 2GS0A 1FHOA 4A5KA 3RCPA 5D3YA 1V5PA 2H7EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GCL A;  4B6H A;  4HAT B;  2FJL A;  2QKM A;  3LJU X;  2X18 A;  5C5B A;  2L2I A;  3CIK A;  2Y7B A;  2YT1 A;  5D3X A;  1V88 A;  3ML4 A;  3SO6 A;  1MAI A;  1Y5O A;  4BBK A;  3PVU A;  5HE3 A;  2LOX A;  2J59 M;  4KVG B;  2P0F A;  3D8F A;  5DHF B;  1DBH A;  2D4Q A;  4YON A;  1J0W A;  1IRS A;  2D9W A;  5FI0 A;  1XR0 B;  1V61 A;  2JP2 A;  1NTV A;  5C5B B;  2DHI A;  2DKP A;  1AWE A;  2D9Y A;  4HAW B;  2L1C A;  2ROZ B;  4HAV B;  2LUL A;  1BTN A;  3SV1 A;  2YSZ A;  2XQN M;  3F5R A;  1V5M A;  1UPQ A;  2J0M A;  1N3H A;  2CY5 A;  2R0D A;  4HAU B;  4IAP A;  3ULC A;  3P7Z A;  2DHK A;  2EMT A;  2DX1 A;  4EJN A;  2DN6 A;  3PZD A;  3ZDT A;  3ODO A;  1H10 A;  1NU2 A;  1QC6 A;  2VKI A;  1X11 A;  5D3V A;  2CAY A;  2UZR A;  4HDQ A;  2D2Q A;  3TCA A;  4EKU A;  5EFX A;  2E2X A;  5DHA B;  1P3R A;  1FOE A;  3ODX A;  1BWN A;  1PLS A;  2W2W A;  1AQC A;  1ZC4 B;  1KZG A;  4ZRI A;  5HE0 A;  2ELB A;  3KRW A;  2I1J A;  1WGQ A;  2MDX A;  1U5F A;  5JHG A;  2K00 A;  1XX0 A;  4P7I A;  1EGX A;  1TJ6 A;  3WA0 A;  1SGH A;  2NZ8 B;  2ADZ A;  4HHV A;  1U29 A;  1X05 A;  4DBB A;  3UZT A;  5JP4 A;  4C0A A;  1LW3 A;  3TO1 A;  3U8Z A;  4PNK A;  5JLJ B;  4HB4 B;  4A6K A;  4NY0 A;  4KHB B;  2ELA A;  4EMO A;  2OTX A;  2MKR A;  5D27 A;  2DX5 A;  3HW2 B;  1P6S A;  1FB8 A;  2EC1 A;  3KY9 A;  1FGY A;  3ULB A;  2ROV A;  4L6E A;  4A6H A;  4DX8 A;  1DRO A;  3BJI A;  2Z0Q A;  2RSG A;  1EVH A;  1PMS A;  4DXA B;  1ZC3 B;  2I1K A;  1M7R A;  2IFS A;  2DKQ A;  4GXB A;  1FHW A;  3DXD A;  2P8V A;  2LKO A;  1H4R A;  1WVH A;  1U5E A;  1B55 A;  4MT7 A;  1W1D A;  2CRF A;  3PEG A;  1I7A A;  2OQB A;  2ZPY A;  3ODW A;  3QBV B;  2UVM A;  2COC A;  1DDM A;  2D9Z A;  2COD A;  2N0Y A;  2W2X D;  1U27 A;  1WGU A;  4K17 A;  1OY2 A;  5HE2 A;  2YVC A;  3DXE A;  2DHJ A;  1WJ1 A;  1FAO A;  4HAX B;  4HDO A;  3SNH A;  2YF0 A;  4YL8 A;  1W1H A;  3VIA A;  2LYD A;  4WJ7 A;  1ZM0 A;  4WVF B;  1OQN A;  4KHO A;  2J0J A;  3X23 A;  1EAZ A;  1MK7 B;  4GN1 A;  3PG7 A;  2YS5 A;  1BAK A;  1UNQ A;  3MPX A;  1KZ7 A;  2K2U A;  4F7H A;  3CXB B;  2K2J A;  1TQZ A;  3FSS A;  1ISN A;  1K5G B;  4TKN A;  2V76 A;  1J19 A;  5J3Q A;  1I2H A;  1MKE A;  1MK9 B;  2LOZ A;  4MK0 A;  5LOP B;  3D8E A;  2Z0P A;  1RJ2 A;  1MPH A;  4HB3 B;  1XKE A;  2MWN B;  3P6A A;  2RVB B;  2RUK B;  2Q13 A;  1V89 A;  2YRY A;  1ZSQ A;  1Q67 A;  2EJ8 A;  1UPR A;  3BIN A;  4Z2N A;  4IOY X;  4MY6 A;  5KQ4 A;  1U5G A;  1EF1 A;  3A8P A;  3OAN A;  2D9V A;  4GMV A;  2KGX B;  1MIX A;  2DLW A;  5D3W A;  4ZRK A;  2H7D A;  3WYF B;  2M38 A;  4K2O A;  3AU5 A;  2I5F A;  3VOQ A;  3KRX A;  4GZU A;  5C79 A;  3PVL A;  3TW1 A;  2RNR B;  3FM8 C;  4DX9 0;  1WI1 A;  4XWX A;  4HAY B;  2GCJ A;  2QKL A;  1E5W A;  2PZ1 A;  2UZS A;  3HK0 A;  1X1F A;  4H8S A;  4F7G A;  2AL6 A;  1LB1 A;  3NSU A;  5J3Y A;  2AEH A;  4IFS A;  4K2P A;  4WSF A;  2G35 A;  4TYZ A;  3SUZ A;  1QQG A;  4HB2 B;  1XOD A;  3TVV A;  3A8Q A;  1FHX A;  2D11 A;  3ZVR A;  1BTK A;  5DH9 B;  4KHA A;  3V5W A;  1FGZ A;  2P0H A;  2CY4 A;  1U5D A;  3N7C A;  1KI1 B;  3A98 B;  2D9X A;  1X1G A;  4KAX B;  5CLQ B;  1V5U A;  2Z0O A;  5C6R A;  2D10 A;  2RLO A;  4ZRJ A;  2P0D A;  2DFK A;  1Y19 B;  3PP2 A;  1Z87 A;  3QIJ A;  4A6F A;  4CYE A;  3O96 A;  3QWM A;  2COF A;  4F7U P;  2RGN B;  2DYQ A;  5CLL B;  2Y8F A;  3TFM A;  3KSY A;  2YT0 A;  3HQC A;  1X86 A;  1UNR A;  3F0W A;  3MDB C;  1WJM A;  2GJY A;  2YS1 A;  3IVF A;  4D0N B;  4CHM A;  3GYO A;  2N23 A;  1MIZ B;  5C16 A;  5KQ1 A;  2DA0 A;  4Z2M B;  4HAZ B;  4GPT B;  2Y8G A;  4A6F B;  3PSC A;  1K5D B;  3G9W A;  1TXD A;  5LON B;  1RRP B;  2NMB A;  2HE7 A;  3AU4 A;  2COA A;  1DDV A;  2HTH B;  5L81 A;  4NSW A;  1NI2 A;  4PQ0 A;  2I5C A;  2M14 A;  1DYN A;  5DIF B;  2VSZ A;  1GC6 A;  3SYX A;  2IYB A;  2KUP A;  1ZVR A;  1PFJ A;  1GC7 A;  3AJ4 A;  1P5T A;  2MFQ A;  1WG7 A;  2J0K A;  3KZ1 A;  3GYP A;  5J3T A;  5DI9 B;  1XCG A;  4K81 A;  1M7E A;  4HB0 B;  5HE1 A;  2YS3 A;  5FI1 A;  2KCJ A;  3PVW A;  1OMW A;  4GMX B;  1XD4 A;  4CHJ A;  1NTY A;  3T06 A;  1U2B A;  2W2X C;  1SHC A;  5GOW B;  1GG3 A;  2LG1 A;  3D8D A;  3FEH A;  2EMS A;  5KCV A;  2DYN A;  2DTC A;  4Y94 A;  1W1G A;  2R09 A;  3M1I B;  1DDW A;  3DXC A;  1UNP A;  5JHH A;  2BCJ A;  1UEF A;  2VRW B;  3U7D A;  2GS0 A;  1FHO A;  4A5K A;  3RCP A;  5D3Y A;  1V5P A;  2H7E A; 
#chains in the Genus database with same CATH topology
 2GCL A;  4B6H A;  4HAT B;  2FJL A;  2QKM A;  3LJU X;  2X18 A;  5C5B A;  2KUQ A;  2L2I A;  3CIK A;  2Y7B A;  2YT1 A;  5D3X A;  1V88 A;  3ML4 A;  3SO6 A;  1MAI A;  2FJU B;  1Y5O A;  4BBK A;  3PVU A;  5HE3 A;  2LOX A;  2J59 M;  4KVG B;  2P0F A;  3D8F A;  5DHF B;  1DBH A;  2D4Q A;  4YON A;  1J0W A;  1IRS A;  2D9W A;  5FI0 A;  1XR0 B;  2Z14 A;  1V61 A;  2JP2 A;  1NTV A;  5C5B B;  2DHI A;  3U12 A;  2DKP A;  1AWE A;  2D9Y A;  4HAW B;  2L1C A;  2ROZ B;  4HAV B;  2LUL A;  1BTN A;  3SV1 A;  2YSZ A;  2XQN M;  3F5R A;  1V5M A;  1UPQ A;  2J0M A;  1N3H A;  2CY5 A;  2R0D A;  4HAU B;  4IAP A;  3ULC A;  5I2M A;  3P7Z A;  2DHK A;  2EMT A;  2DX1 A;  4EJN A;  2DN6 A;  3PZD A;  3ZDT A;  5IRS A;  2YT2 A;  3ODO A;  1H10 A;  1NU2 A;  1QC6 A;  2VKI A;  1X11 A;  5D3V A;  2CAY A;  2UZR A;  4HDQ A;  2D2Q A;  4GNK B;  3TCA A;  4EKU A;  3DCX A;  5EFX A;  2E2X A;  5DHA B;  2RRF A;  1P3R A;  1FOE A;  3ODX A;  1BWN A;  1PLS A;  2W2W A;  4DIX A;  1AQC A;  1ZC4 B;  2R2Y A;  1KZG A;  4ZRI A;  5HE0 A;  2ELB A;  3KRW A;  2I1J A;  1WGQ A;  2MDX A;  1U5F A;  5JHG A;  2K00 A;  4KHB A;  1XX0 A;  3HSA A;  4P7I A;  1EGX A;  1TJ6 A;  4HSI A;  3WA0 A;  1SGH A;  2NZ8 B;  2ADZ A;  4HHV A;  1U29 A;  1X05 A;  4OT1 A;  4DBB A;  3UZT A;  4QXA B;  5JP4 A;  4CSQ A;  4C0A A;  1LW3 A;  3TO1 A;  3U8Z A;  4L1R A;  4PNK A;  3HIE A;  5JLJ B;  4HB4 B;  4A6K A;  3NW8 A;  4NY0 A;  4KHB B;  2ELA A;  4EMO A;  2OTX A;  2MKR A;  5D27 A;  2DX5 A;  3HW2 B;  1P6S A;  1FB8 A;  2EC1 A;  3KY9 A;  1FGY A;  3ULB A;  2ROV A;  4L6E A;  4A6H A;  4DX8 A;  1DRO A;  3BJI A;  2Z0Q A;  2RSG A;  1EVH A;  1PMS A;  4DXA B;  1ZC3 B;  2I1K A;  1M7R A;  2IFS A;  2DKQ A;  3A58 A;  4GXB A;  1FHW A;  3DXD A;  2P8V A;  3NWD A;  2LKO A;  1H4R A;  1WVH A;  1U5E A;  1B55 A;  4MT7 A;  1W1D A;  2CRF A;  2GUM A;  3PEG A;  1I7A A;  2OQB A;  2ZPY A;  3ODW A;  3QBV B;  2UVM A;  2COC A;  1DDM A;  2D9Z A;  2COD A;  2N0Y A;  2W2X D;  1U27 A;  1WGU A;  4K17 A;  1OY2 A;  5HE2 A;  2YVC A;  1MI1 A;  1T77 A;  3DXE A;  2DHJ A;  1WJ1 A;  1FAO A;  4HAX B;  4HDO A;  3SNH A;  2YF0 A;  4YL8 A;  1W1H A;  3VIA A;  5LG4 B;  2LYD A;  4WJ7 A;  2KIG A;  1ZM0 A;  4WVF B;  1OQN A;  4KHO A;  2J0J A;  3X23 A;  1EAZ A;  5M4Y B;  1MK7 B;  4GN1 A;  3PG7 A;  3OHM B;  2YS5 A;  1BAK A;  1UNQ A;  2K2U A;  1KZ7 A;  3MPX A;  4F7H A;  3CXB B;  2K2J A;  1TQZ A;  3FSS A;  1ISN A;  1K5G B;  4QJ5 B;  4TKN A;  2V76 A;  4GOU A;  1J19 A;  5J3Q A;  1I2H A;  1MKE A;  1MK9 B;  2LOZ A;  4MK0 A;  2KIE A;  5LOP B;  4QJ3 B;  3D8E A;  2Z0P A;  1RJ2 A;  1MPH A;  4HB3 B;  1XKE A;  2MWN B;  3P6A A;  2RVB B;  2RUK B;  2Q13 A;  1V89 A;  2YRY A;  2KR0 A;  1ZSQ A;  1Q67 A;  2EJ8 A;  1UPR A;  3BIN A;  4Z2N A;  4IOY X;  4MY6 A;  5KQ4 A;  1U5G A;  1EF1 A;  3A8P A;  3OAN A;  2D9V A;  2Z59 A;  4GMV A;  2KGX B;  1MIX A;  2DLW A;  5D3W A;  4ZRK A;  2H7D A;  3WYF B;  2M38 A;  4K2O A;  3AU5 A;  2K8E A;  2I5F A;  3VOQ A;  3KRX A;  4GZU A;  5C79 A;  3PVL A;  3TW1 A;  2RNR B;  3FM8 C;  4DX9 0;  1WI1 A;  4XWX A;  4HAY B;  2GCJ A;  2QKL A;  1E5W A;  2PZ1 A;  2UZS A;  3HK0 A;  2Z13 A;  1X1F A;  4H8S A;  4F7G A;  2AL6 A;  1LB1 A;  3NSU A;  5J3Y A;  2AEH A;  4IFS A;  4K2P A;  4WSF A;  2G35 A;  4TYZ A;  3SUZ A;  1QQG A;  4HB2 B;  1XOD A;  3TVV A;  3A8Q A;  3FVC A;  2ZKM X;  1FHX A;  2D11 A;  3ZVR A;  1BTK A;  5DH9 B;  4KHA A;  3V5W A;  1FGZ A;  2P0H A;  2CY4 A;  1U5D A;  3N7C A;  1KI1 B;  3A98 B;  2D9X A;  1X1G A;  4KAX B;  5CLQ B;  1V5U A;  2Z0O A;  2NBV A;  2D10 A;  2RLO A;  5C6R A;  4ZRJ A;  2P0D A;  2DFK A;  1Y19 B;  3PP2 A;  1Z87 A;  3QIJ A;  4A6F A;  4CYE A;  3O96 A;  3QWM A;  2COF A;  4F7U P;  2RGN B;  2DYQ A;  5CLL B;  2Y8F A;  3TFM A;  3KSY A;  2YT0 A;  3HQC A;  1X86 A;  1UNR A;  3F0W A;  3MDB C;  4QJ4 B;  1WJM A;  2GJY A;  2YS1 A;  3IVF A;  4D0N B;  4CHM A;  3GYO A;  2N23 A;  1MIZ B;  5C16 A;  5KQ1 A;  2DA0 A;  4Z2M B;  4HAZ B;  4GPT B;  2Y8G A;  4A6F B;  3PSC A;  1K5D B;  3G9W A;  1TXD A;  5LON B;  1RRP B;  2NMB A;  2HE7 A;  3AU4 A;  2COA A;  1DDV A;  3NWA A;  2HTH B;  4D6W A;  5L81 A;  4NSW A;  1NI2 A;  4PQ0 A;  2I5C A;  2M14 A;  1DYN A;  5DIF B;  2VSZ A;  1GC6 A;  3B77 A;  3SYX A;  2IYB A;  2KUP A;  1ZVR A;  1PFJ A;  1GC7 A;  3AJ4 A;  1P5T A;  2MFQ A;  1WG7 A;  2J0K A;  3KZ1 A;  3GYP A;  5J3T A;  5I2S A;  5DI9 B;  1XCG A;  3NWF A;  4K81 A;  1M7E A;  4HB0 B;  5HE1 A;  2YS3 A;  5FI1 A;  2K49 A;  2KCJ A;  1ZYI A;  3PVW A;  4OSN A;  1OMW A;  4GMX B;  1XD4 A;  4CHJ A;  1NTY A;  3T06 A;  1U2B A;  2Z4D A;  2W2X C;  1SHC A;  5GOW B;  1GG3 A;  2LG1 A;  3D8D A;  3FEH A;  2EMS A;  5KCV A;  2DYN A;  2DTC A;  4Y94 A;  1W1G A;  2R09 A;  3M1I B;  1DDW A;  3DXC A;  1UNP A;  5JHH A;  2BCJ A;  1UEF A;  2VRW B;  3U7D A;  2GS0 A;  1FHO A;  4A5K A;  3RCP A;  5D3Y A;  1V5P A;  2H7E A; 
#chains in the Genus database with same CATH homology
 2GCL A;  4B6H A;  4HAT B;  2FJL A;  2QKM A;  3LJU X;  2X18 A;  5C5B A;  2L2I A;  3CIK A;  2Y7B A;  2YT1 A;  5D3X A;  1V88 A;  3ML4 A;  3SO6 A;  1MAI A;  1Y5O A;  4BBK A;  3PVU A;  5HE3 A;  2LOX A;  2J59 M;  4KVG B;  2P0F A;  3D8F A;  5DHF B;  1DBH A;  2D4Q A;  4YON A;  1J0W A;  1IRS A;  2D9W A;  5FI0 A;  1XR0 B;  1V61 A;  2JP2 A;  1NTV A;  5C5B B;  2DHI A;  2DKP A;  1AWE A;  2D9Y A;  4HAW B;  2L1C A;  2ROZ B;  4HAV B;  2LUL A;  1BTN A;  3SV1 A;  2YSZ A;  2XQN M;  3F5R A;  1V5M A;  1UPQ A;  2J0M A;  1N3H A;  2CY5 A;  2R0D A;  4HAU B;  4IAP A;  3ULC A;  3P7Z A;  2DHK A;  2EMT A;  2DX1 A;  4EJN A;  2DN6 A;  3PZD A;  3ZDT A;  3ODO A;  1H10 A;  1NU2 A;  1QC6 A;  2VKI A;  1X11 A;  5D3V A;  2CAY A;  2UZR A;  4HDQ A;  2D2Q A;  3TCA A;  4EKU A;  5EFX A;  2E2X A;  5DHA B;  1P3R A;  1FOE A;  3ODX A;  1BWN A;  1PLS A;  2W2W A;  1AQC A;  1ZC4 B;  1KZG A;  4ZRI A;  5HE0 A;  2ELB A;  3KRW A;  2I1J A;  1WGQ A;  2MDX A;  1U5F A;  5JHG A;  2K00 A;  1XX0 A;  4P7I A;  1EGX A;  1TJ6 A;  3WA0 A;  1SGH A;  2NZ8 B;  2ADZ A;  4HHV A;  1U29 A;  1X05 A;  4DBB A;  3UZT A;  5JP4 A;  4C0A A;  1LW3 A;  3TO1 A;  3U8Z A;  4PNK A;  5JLJ B;  4HB4 B;  4A6K A;  4NY0 A;  4KHB B;  2ELA A;  4EMO A;  2OTX A;  2MKR A;  5D27 A;  2DX5 A;  3HW2 B;  1P6S A;  1FB8 A;  2EC1 A;  3KY9 A;  1FGY A;  3ULB A;  2ROV A;  4L6E A;  4A6H A;  4DX8 A;  1DRO A;  3BJI A;  2Z0Q A;  2RSG A;  1EVH A;  1PMS A;  4DXA B;  1ZC3 B;  2I1K A;  1M7R A;  2IFS A;  2DKQ A;  4GXB A;  1FHW A;  3DXD A;  2P8V A;  2LKO A;  1H4R A;  1WVH A;  1U5E A;  1B55 A;  4MT7 A;  1W1D A;  2CRF A;  3PEG A;  1I7A A;  2OQB A;  2ZPY A;  3ODW A;  3QBV B;  2UVM A;  2COC A;  1DDM A;  2D9Z A;  2COD A;  2N0Y A;  2W2X D;  1U27 A;  1WGU A;  4K17 A;  1OY2 A;  5HE2 A;  2YVC A;  3DXE A;  2DHJ A;  1WJ1 A;  1FAO A;  4HAX B;  4HDO A;  3SNH A;  2YF0 A;  4YL8 A;  1W1H A;  3VIA A;  2LYD A;  4WJ7 A;  1ZM0 A;  4WVF B;  1OQN A;  4KHO A;  2J0J A;  3X23 A;  1EAZ A;  1MK7 B;  4GN1 A;  3PG7 A;  2YS5 A;  1BAK A;  1UNQ A;  3MPX A;  1KZ7 A;  2K2U A;  4F7H A;  3CXB B;  2K2J A;  1TQZ A;  3FSS A;  1ISN A;  1K5G B;  4TKN A;  2V76 A;  1J19 A;  5J3Q A;  1I2H A;  1MKE A;  1MK9 B;  2LOZ A;  4MK0 A;  5LOP B;  3D8E A;  2Z0P A;  1RJ2 A;  1MPH A;  4HB3 B;  1XKE A;  2MWN B;  3P6A A;  2RVB B;  2RUK B;  2Q13 A;  1V89 A;  2YRY A;  1ZSQ A;  1Q67 A;  2EJ8 A;  1UPR A;  3BIN A;  4Z2N A;  4IOY X;  4MY6 A;  5KQ4 A;  1U5G A;  1EF1 A;  3A8P A;  3OAN A;  2D9V A;  4GMV A;  2KGX B;  1MIX A;  2DLW A;  5D3W A;  4ZRK A;  2H7D A;  3WYF B;  2M38 A;  4K2O A;  3AU5 A;  2I5F A;  3VOQ A;  3KRX A;  4GZU A;  5C79 A;  3PVL A;  3TW1 A;  2RNR B;  3FM8 C;  4DX9 0;  1WI1 A;  4XWX A;  4HAY B;  2GCJ A;  2QKL A;  1E5W A;  2PZ1 A;  2UZS A;  3HK0 A;  1X1F A;  4H8S A;  4F7G A;  2AL6 A;  1LB1 A;  3NSU A;  5J3Y A;  2AEH A;  4IFS A;  4K2P A;  4WSF A;  2G35 A;  4TYZ A;  3SUZ A;  1QQG A;  4HB2 B;  1XOD A;  3TVV A;  3A8Q A;  1FHX A;  2D11 A;  3ZVR A;  1BTK A;  5DH9 B;  4KHA A;  3V5W A;  1FGZ A;  2P0H A;  2CY4 A;  1U5D A;  3N7C A;  1KI1 B;  3A98 B;  2D9X A;  1X1G A;  4KAX B;  5CLQ B;  1V5U A;  2Z0O A;  5C6R A;  2D10 A;  2RLO A;  4ZRJ A;  2P0D A;  2DFK A;  1Y19 B;  3PP2 A;  1Z87 A;  3QIJ A;  4A6F A;  4CYE A;  3O96 A;  3QWM A;  2COF A;  4F7U P;  2RGN B;  2DYQ A;  5CLL B;  2Y8F A;  3TFM A;  3KSY A;  2YT0 A;  3HQC A;  1X86 A;  1UNR A;  3F0W A;  3MDB C;  1WJM A;  2GJY A;  2YS1 A;  3IVF A;  4D0N B;  4CHM A;  3GYO A;  2N23 A;  1MIZ B;  5C16 A;  5KQ1 A;  2DA0 A;  4Z2M B;  4HAZ B;  4GPT B;  2Y8G A;  4A6F B;  3PSC A;  1K5D B;  3G9W A;  1TXD A;  5LON B;  1RRP B;  2NMB A;  2HE7 A;  3AU4 A;  2COA A;  1DDV A;  2HTH B;  5L81 A;  4NSW A;  1NI2 A;  4PQ0 A;  2I5C A;  2M14 A;  1DYN A;  5DIF B;  2VSZ A;  1GC6 A;  3SYX A;  2IYB A;  2KUP A;  1ZVR A;  1PFJ A;  1GC7 A;  3AJ4 A;  1P5T A;  2MFQ A;  1WG7 A;  2J0K A;  3KZ1 A;  3GYP A;  5J3T A;  5DI9 B;  1XCG A;  4K81 A;  1M7E A;  4HB0 B;  5HE1 A;  2YS3 A;  5FI1 A;  2KCJ A;  3PVW A;  1OMW A;  4GMX B;  1XD4 A;  4CHJ A;  1NTY A;  3T06 A;  1U2B A;  2W2X C;  1SHC A;  5GOW B;  1GG3 A;  2LG1 A;  3D8D A;  3FEH A;  2EMS A;  5KCV A;  2DYN A;  2DTC A;  4Y94 A;  1W1G A;  2R09 A;  3M1I B;  1DDW A;  3DXC A;  1UNP A;  5JHH A;  2BCJ A;  1UEF A;  2VRW B;  3U7D A;  2GS0 A;  1FHO A;  4A5K A;  3RCP A;  5D3Y A;  1V5P A;  2H7E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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