1BWNA

Ph domain and btk motif from bruton's tyrosine kinase mutant e41k in complex with ins(1,3,4,5)p4
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
169
structure length
166
Chain Sequence
AAVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYKYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIPRRGSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILEN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords BRUTON'S TYROSINE KINASE
total genus 36
structure length 166
sequence length 169
chains with identical sequence B
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 1998-09-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF00779 BTK BTK motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1bwnA00
4Y94A 2LOZA 5GOWB 5HE1A 4HDQA 5C16A 1XODA 1I2HA 4MY6A 1FAOA 2D9ZA 2I1KA 2ELBA 4CHMA 5KCVA 1QC6A 2P0HA 2CODA 2J0JA 1QQGA 1MIZB 3G9WA 2GCLA 1RJ2A 2Y7BA 5L81A 2D2QA 2FJLA 2UVMA 1U27A 1V5PA 1NI2A 4C0AA 3AJ4A 1MAIA 4CHJA 3ZVRA 1ZC4B 4EMOA 1P5TA 2H7DA 2M38A 5D3XA 2EMTA 1GC7A 3WA0A 3KRXA 2OTXA 1U5DA 1U29A 1FGYA 4K17A 2YT1A 2DYNA 1UPRA 3KZ1A 5HE2A 2QKLA 5HE3A 1I7AA 2Z0PA 3PVUA 2CY4A 2N0YA 5DIFB 5J3TA 1GG3A 1EVHA 1KZGA 2NMBA 3D8EA 1X1FA 2VRWB 4HAUB 2M14A 3MDBC 1ZSQA 2X18A 5FI0A 1H10A 1M7RA 3PVWA 3WYFB 4DX8A 3T06A 3SO6A 1UEFA 2L2IA 4GN1A 3TFMA 1FGZA 3FEHA 4KHOA 3U7DA 4K2OA 2MDXA 5CLLB 1OY2A 2L1CA 5DI9B 2DX5A 4HATB 1K5GB 3PEGA 2KUPA 2MKRA 4HB0B 2I5CA 5C5BB 2K2JA 3X23A 2GS0A 5C5BA 4GZUA 4MT7A 2LYDA 4HB4B 4GXBA 5D3YA 2ROVA 2NZ8B 2CAYA 4EKUA 4WVFB 5JP4A 4HAYB 1XKEA 4HB2B 1UPQA 3N7CA 3PZDA 1XCGA 4CYEA 1OQNA 5JLJB 1V5UA 2J0KA 4NSWA 1SHCA 2VSZA 1P6SA 1U5FA 1ZM0A 2EC1A 2YS3A 3BINA 4HHVA 5J3YA 5FI1A 3SUZA 1TJ6A 4DXAB 1NU2A 2MWNB 4A6KA 1B55A 1V88A 4A6HA 1X86A 4BBKA 3DXCA 3F0WA 3A98B 2KGXB 2YF0A 2K2UA 1W1DA 4TKNA 4ZRJA 2LKOA 3PSCA 2YVCA 3QWMA 3D8DA 2R09A 1WG7A 2D10A 3PP2A 2D11A 1FB8A 1H4RA 4K81A 5CLQB 4KHAA 1LB1A 3ODWA 5LONB 1MK9B 2DA0A 2Z0QA 1ZC3B 2RNRB 2V76A 4Z2NA 2GJYA 1WJMA 4TYZA 4WJ7A 4HAWB 2P8VA 4DX90 3CXBB 1W1GA 1X1GA 2H7EA 4ZRIA 3HW2B 2W2XC 2DKPA 5J3QA 4XWXA 1PLSA 1OMWA 2QKMA 3TCAA 4EJNA 3QBVB 1GC6A 2EMSA 4KHBB 1BTKA 1BWNA 3DXDA 1P3RA 4Z2MB 2ROZB 3LJUX 4IOYX 2COAA 2RLOA 4WSFA 4KAXB 1DYNA 1V5MA 2HTHB 2UZSA 2P0FA 3DXEA 4K2PA 4YONA 2MFQA 3IVFA 3KRWA 1NTVA 4YL8A 4NY0A 2GCJA 3F5RA 5D3WA 3M1IB 3P7ZA 1EAZA 1M7EA 3RCPA 1KZ7A 1TXDA 3GYOA 1J0WA 2DYQA 2J0MA 3ML4A 1AQCA 3TW1A 4A5KA 2ZPYA 2G35A 2LG1A 1U2BA 4KVGB 4DBBA 4GMVA 3VOQA 4B6HA 1ZVRA 4HB3B 3BJIA 1FHOA 1Y5OA 1DDMA 4ZRKA 4F7UP 1WGUA 2W2XD 4P7IA 2LULA 2AL6A 2LOXA 1LW3A 2YS1A 5KQ1A 5C79A 2RGNB 3SNHA 5DHAB 3P6AA 2I5FA 2DLWA 4PQ0A 3ULBA 2COCA 2YT0A 1N3HA 1DROA 2DHIA 4F7HA 1WJ1A 4HAXB 3D8FA 3AU4A 3KSYA 1MPHA 1AWEA 5JHGA 2IYBA 2D9XA 5JHHA 3O96A 2D9WA 3ODOA 1KI1B 3TO1A 3ZDTA 5D3VA 3U8ZA 3QIJA 2DTCA 2BCJA 3SYXA 4H8SA 1FHWA 3FM8C 1XR0B 2HE7A 1WGQA 1FHXA 1MKEA 3V5WA 1Z87A 2YS5A 4HAZB 2D9VA 2DN6A 3NSUA 2Y8FA 2R0DA 4MK0A 2KCJA 1DBHA 4IFSA 1J19A 2DHKA 3PG7A 3SV1A 2ELAA 1U5EA 3OANA 3HK0A 3ULCA 1Y19B 2RSGA 2DX1A 1WVHA 3A8QA 1MK7B 2ADZA 3KY9A 3PVLA 3ODXA 2E2XA 1EGXA 3AU5A 1E5WA 2DHJA 1W1HA 1SGHA 1XD4A 2CRFA 1U5GA 1BTNA 1NTYA 3A8PA 5C6RA 4IAPA 1WI1A 1ISNA 5HE0A 1X05A 2RVBB 2I1JA 3GYPA 1PFJA 1RRPB 3VIAA 1V61A 2CY5A 3MPXA 5LOPB 2OQBA 2COFA 1UNRA 4F7GA 1MIXA 2D4QA 1X11A 4PNKA 1BAKA 2EJ8A 2DKQA 4GMXB 1DDWA 5D27A 2D9YA 2IFSA 1IRSA 2UZRA 5KQ4A 2JP2A 4A6FB 4D0NB 4HAVB 1PMSA 4A6FA 5EFXA 1EF1A 2W2WA 4HDOA 2N23A 2AEHA 2YSZA 1XX0A 1UNQA 3UZTA 4GPTB 2Y8GA 2P0DA 2VKIA 1TQZA 3CIKA 3FSSA 2RUKB 5DH9B 2Z0OA 1FOEA 2YRYA 2J59M 1DDVA 2XQNM 2PZ1A 4L6EA 1V89A 3HQCA 5DHFB 2K00A 1Q67A 2DFKA 2Q13A 1UNPA 1K5DB 3TVVA
chains in the Genus database with same CATH superfamily
4Y94A 2LOZA 5GOWB 5HE1A 4HDQA 5C16A 1XODA 2GUMA 1I2HA 4MY6A 1FAOA 2D9ZA 2I1KA 2ELBA 4CHMA 5KCVA 1QC6A 2P0HA 4OT1A 4QJ5B 2CODA 2J0JA 1QQGA 1MIZB 3G9WA 2GCLA 2ZKMX 1RJ2A 2Y7BA 5L81A 2D2QA 2FJLA 2UVMA 1U27A 1V5PA 1NI2A 4C0AA 3AJ4A 1MAIA 4CHJA 3ZVRA 1ZC4B 4EMOA 1P5TA 2H7DA 2M38A 5D3XA 2EMTA 1GC7A 3WA0A 3KRXA 2OTXA 1U5DA 1U29A 1FGYA 4K17A 2YT1A 2DYNA 1UPRA 3KZ1A 5HE2A 2QKLA 5HE3A 1I7AA 2Z0PA 3PVUA 2CY4A 2N0YA 5DIFB 5J3TA 1GG3A 1EVHA 1KZGA 2NMBA 3D8EA 1X1FA 2VRWB 4HAUB 2M14A 3MDBC 1ZSQA 2X18A 5FI0A 1H10A 1M7RA 3PVWA 3WYFB 4DX8A 3T06A 3SO6A 1UEFA 3DCXA 2RRFA 4QXAB 2L2IA 4GN1A 3FVCA 3TFMA 1MI1A 1FGZA 3FEHA 4KHOA 3U7DA 4K2OA 2MDXA 5CLLB 4QJ3B 1OY2A 2L1CA 5DI9B 2DX5A 4HATB 1K5GB 3PEGA 2KUPA 2MKRA 4HB0B 2I5CA 5C5BB 4HSIA 2K2JA 3X23A 2GS0A 5C5BA 4GZUA 4MT7A 2LYDA 4HB4B 4CSQA 4GXBA 5D3YA 2ROVA 2NZ8B 2Z4DA 2CAYA 4EKUA 4OSNA 4WVFB 3NW8A 5JP4A 4HAYB 1XKEA 4HB2B 1UPQA 3N7CA 3PZDA 1XCGA 4CYEA 1OQNA 5JLJB 1V5UA 2J0KA 4NSWA 1SHCA 2VSZA 1P6SA 1U5FA 1ZM0A 2EC1A 2YS3A 3BINA 4HHVA 5J3YA 5FI1A 3SUZA 1TJ6A 3U12A 4DXAB 1NU2A 2MWNB 4A6KA 5I2SA 1B55A 1V88A 4A6HA 1X86A 4BBKA 3DXCA 3F0WA 3A98B 2KGXB 2YF0A 2K2UA 3HIEA 1W1DA 4TKNA 4ZRJA 2LKOA 3PSCA 2YVCA 3B77A 3QWMA 4GNKB 3D8DA 2R09A 1WG7A 2D10A 3PP2A 2D11A 1FB8A 1H4RA 4K81A 5CLQB 4KHAA 1LB1A 3ODWA 5LONB 1MK9B 2DA0A 2Z0QA 1ZC3B 2RNRB 2V76A 2FJUB 4Z2NA 2GJYA 1WJMA 4TYZA 4WJ7A 4HAWB 2P8VA 4DX90 3CXBB 1W1GA 1X1GA 2H7EA 4ZRIA 3HW2B 2W2XC 2DKPA 2K8EA 5J3QA 4XWXA 2Z13A 1PLSA 1OMWA 2KUQA 2QKMA 3TCAA 4EJNA 3QBVB 1GC6A 2EMSA 4KHBB 1BTKA 1BWNA 2YT2A 3DXDA 3HSAA 1P3RA 4KHBA 4Z2MB 2ROZB 3LJUX 4IOYX 2COAA 2RLOA 4WSFA 4KAXB 1DYNA 1V5MA 2HTHB 2UZSA 3A58A 2P0FA 3DXEA 4K2PA 4QJ4B 1ZYIA 4YONA 2MFQA 3IVFA 3KRWA 1NTVA 4YL8A 4NY0A 2GCJA 3F5RA 5D3WA 3M1IB 3P7ZA 1EAZA 1M7EA 3RCPA 2KR0A 3OHMB 1KZ7A 1TXDA 1T77A 3GYOA 2KIGA 1J0WA 2DYQA 2J0MA 3ML4A 1AQCA 3TW1A 4A5KA 2ZPYA 2G35A 2LG1A 1U2BA 4KVGB 4DBBA 4GMVA 3VOQA 4B6HA 1ZVRA 4HB3B 3BJIA 1FHOA 3NWFA 1Y5OA 1DDMA 4ZRKA 4F7UP 1WGUA 2W2XD 4P7IA 2LULA 2AL6A 2LOXA 1LW3A 2YS1A 5KQ1A 5C79A 2RGNB 3SNHA 2Z59A 5DHAB 3P6AA 2I5FA 2DLWA 4PQ0A 3ULBA 2COCA 2YT0A 1N3HA 1DROA 2DHIA 3NWDA 4F7HA 1WJ1A 4HAXB 3D8FA 3AU4A 3KSYA 1MPHA 1AWEA 5JHGA 2IYBA 2D9XA 5JHHA 3O96A 2K49A 2D9WA 3ODOA 1KI1B 3TO1A 3ZDTA 5D3VA 3U8ZA 3QIJA 2DTCA 2BCJA 3SYXA 4H8SA 1FHWA 3FM8C 1XR0B 2HE7A 1WGQA 1FHXA 1MKEA 3V5WA 1Z87A 2YS5A 4HAZB 2D9VA 2DN6A 3NSUA 2Y8FA 3NWAA 2R0DA 4MK0A 2KCJA 1DBHA 4IFSA 1J19A 2DHKA 3PG7A 3SV1A 2ELAA 1U5EA 3OANA 3HK0A 3ULCA 4DIXA 2Z14A 1Y19B 2RSGA 2DX1A 1WVHA 3A8QA 1MK7B 2ADZA 3KY9A 3PVLA 3ODXA 2E2XA 1EGXA 3AU5A 1E5WA 2DHJA 1W1HA 1SGHA 1XD4A 2CRFA 1U5GA 4GOUA 1BTNA 1NTYA 3A8PA 5C6RA 4IAPA 1WI1A 1ISNA 2NBVA 5HE0A 1X05A 5LG4B 2RVBB 2I1JA 3GYPA 1PFJA 1RRPB 3VIAA 1V61A 2CY5A 3MPXA 5LOPB 2OQBA 2COFA 1UNRA 4F7GA 1MIXA 2D4QA 1X11A 4PNKA 1BAKA 2EJ8A 2DKQA 4GMXB 1DDWA 5M4YB 5D27A 2D9YA 2IFSA 1IRSA 2UZRA 5KQ4A 2JP2A 2KIEA 4A6FB 4D0NB 4HAVB 1PMSA 2R2YA 4A6FA 5EFXA 1EF1A 2W2WA 4HDOA 2N23A 2AEHA 2YSZA 5IRSA 1XX0A 4D6WA 1UNQA 3UZTA 4GPTB 2Y8GA 2P0DA 2VKIA 1TQZA 3CIKA 3FSSA 2RUKB 5DH9B 2Z0OA 1FOEA 2YRYA 2J59M 1DDVA 2XQNM 2PZ1A 4L6EA 1V89A 4L1RA 3HQCA 5DHFB 2K00A 5I2MA 1Q67A 2DFKA 2Q13A 1UNPA 1K5DB 3TVVA
chains in the Genus database with same CATH topology
4Y94A 2LOZA 5GOWB 5HE1A 4HDQA 5C16A 1XODA 1I2HA 4MY6A 1FAOA 2D9ZA 2I1KA 2ELBA 4CHMA 5KCVA 1QC6A 2P0HA 2CODA 2J0JA 1QQGA 1MIZB 3G9WA 2GCLA 1RJ2A 2Y7BA 5L81A 2D2QA 2FJLA 2UVMA 1U27A 1V5PA 1NI2A 4C0AA 3AJ4A 1MAIA 4CHJA 3ZVRA 1ZC4B 4EMOA 1P5TA 2H7DA 2M38A 5D3XA 2EMTA 1GC7A 3WA0A 3KRXA 2OTXA 1U5DA 1U29A 1FGYA 4K17A 2YT1A 2DYNA 1UPRA 3KZ1A 5HE2A 2QKLA 5HE3A 1I7AA 2Z0PA 3PVUA 2CY4A 2N0YA 5DIFB 5J3TA 1GG3A 1EVHA 1KZGA 2NMBA 3D8EA 1X1FA 2VRWB 4HAUB 2M14A 3MDBC 1ZSQA 2X18A 5FI0A 1H10A 1M7RA 3PVWA 3WYFB 4DX8A 3T06A 3SO6A 1UEFA 2L2IA 4GN1A 3TFMA 1FGZA 3FEHA 4KHOA 3U7DA 4K2OA 2MDXA 5CLLB 1OY2A 2L1CA 5DI9B 2DX5A 4HATB 1K5GB 3PEGA 2KUPA 2MKRA 4HB0B 2I5CA 5C5BB 2K2JA 3X23A 2GS0A 5C5BA 4GZUA 4MT7A 2LYDA 4HB4B 4GXBA 5D3YA 2ROVA 2NZ8B 2CAYA 4EKUA 4WVFB 5JP4A 4HAYB 1XKEA 4HB2B 1UPQA 3N7CA 3PZDA 1XCGA 4CYEA 1OQNA 5JLJB 1V5UA 2J0KA 4NSWA 1SHCA 2VSZA 1P6SA 1U5FA 1ZM0A 2EC1A 2YS3A 3BINA 4HHVA 5J3YA 5FI1A 3SUZA 1TJ6A 4DXAB 1NU2A 2MWNB 4A6KA 1B55A 1V88A 4A6HA 1X86A 4BBKA 3DXCA 3F0WA 3A98B 2KGXB 2YF0A 2K2UA 1W1DA 4TKNA 4ZRJA 2LKOA 3PSCA 2YVCA 3QWMA 3D8DA 2R09A 1WG7A 2D10A 3PP2A 2D11A 1FB8A 1H4RA 4K81A 5CLQB 4KHAA 1LB1A 3ODWA 5LONB 1MK9B 2DA0A 2Z0QA 1ZC3B 2RNRB 2V76A 4Z2NA 2GJYA 1WJMA 4TYZA 4WJ7A 4HAWB 2P8VA 4DX90 3CXBB 1W1GA 1X1GA 2H7EA 4ZRIA 3HW2B 2W2XC 2DKPA 5J3QA 4XWXA 1PLSA 1OMWA 2QKMA 3TCAA 4EJNA 3QBVB 1GC6A 2EMSA 4KHBB 1BTKA 1BWNA 3DXDA 1P3RA 4Z2MB 2ROZB 3LJUX 4IOYX 2COAA 2RLOA 4WSFA 4KAXB 1DYNA 1V5MA 2HTHB 2UZSA 2P0FA 3DXEA 4K2PA 4YONA 2MFQA 3IVFA 3KRWA 1NTVA 4YL8A 4NY0A 2GCJA 3F5RA 5D3WA 3M1IB 3P7ZA 1EAZA 1M7EA 3RCPA 1KZ7A 1TXDA 3GYOA 1J0WA 2DYQA 2J0MA 3ML4A 1AQCA 3TW1A 4A5KA 2ZPYA 2G35A 2LG1A 1U2BA 4KVGB 4DBBA 4GMVA 3VOQA 4B6HA 1ZVRA 4HB3B 3BJIA 1FHOA 1Y5OA 1DDMA 4ZRKA 4F7UP 1WGUA 2W2XD 4P7IA 2LULA 2AL6A 2LOXA 1LW3A 2YS1A 5KQ1A 5C79A 2RGNB 3SNHA 5DHAB 3P6AA 2I5FA 2DLWA 4PQ0A 3ULBA 2COCA 2YT0A 1N3HA 1DROA 2DHIA 4F7HA 1WJ1A 4HAXB 3D8FA 3AU4A 3KSYA 1MPHA 1AWEA 5JHGA 2IYBA 2D9XA 5JHHA 3O96A 2D9WA 3ODOA 1KI1B 3TO1A 3ZDTA 5D3VA 3U8ZA 3QIJA 2DTCA 2BCJA 3SYXA 4H8SA 1FHWA 3FM8C 1XR0B 2HE7A 1WGQA 1FHXA 1MKEA 3V5WA 1Z87A 2YS5A 4HAZB 2D9VA 2DN6A 3NSUA 2Y8FA 2R0DA 4MK0A 2KCJA 1DBHA 4IFSA 1J19A 2DHKA 3PG7A 3SV1A 2ELAA 1U5EA 3OANA 3HK0A 3ULCA 1Y19B 2RSGA 2DX1A 1WVHA 3A8QA 1MK7B 2ADZA 3KY9A 3PVLA 3ODXA 2E2XA 1EGXA 3AU5A 1E5WA 2DHJA 1W1HA 1SGHA 1XD4A 2CRFA 1U5GA 1BTNA 1NTYA 3A8PA 5C6RA 4IAPA 1WI1A 1ISNA 5HE0A 1X05A 2RVBB 2I1JA 3GYPA 1PFJA 1RRPB 3VIAA 1V61A 2CY5A 3MPXA 5LOPB 2OQBA 2COFA 1UNRA 4F7GA 1MIXA 2D4QA 1X11A 4PNKA 1BAKA 2EJ8A 2DKQA 4GMXB 1DDWA 5D27A 2D9YA 2IFSA 1IRSA 2UZRA 5KQ4A 2JP2A 4A6FB 4D0NB 4HAVB 1PMSA 4A6FA 5EFXA 1EF1A 2W2WA 4HDOA 2N23A 2AEHA 2YSZA 1XX0A 1UNQA 3UZTA 4GPTB 2Y8GA 2P0DA 2VKIA 1TQZA 3CIKA 3FSSA 2RUKB 5DH9B 2Z0OA 1FOEA 2YRYA 2J59M 1DDVA 2XQNM 2PZ1A 4L6EA 1V89A 3HQCA 5DHFB 2K00A 1Q67A 2DFKA 2Q13A 1UNPA 1K5DB 3TVVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Y94 A;  2LOZ A;  5GOW B;  5HE1 A;  4HDQ A;  5C16 A;  1XOD A;  1I2H A;  4MY6 A;  1FAO A;  2D9Z A;  2I1K A;  2ELB A;  4CHM A;  5KCV A;  1QC6 A;  2P0H A;  2COD A;  2J0J A;  1QQG A;  1MIZ B;  3G9W A;  2GCL A;  1RJ2 A;  2Y7B A;  5L81 A;  2D2Q A;  2FJL A;  2UVM A;  1U27 A;  1V5P A;  1NI2 A;  4C0A A;  3AJ4 A;  1MAI A;  4CHJ A;  3ZVR A;  1ZC4 B;  4EMO A;  1P5T A;  2H7D A;  2M38 A;  5D3X A;  2EMT A;  1GC7 A;  3WA0 A;  3KRX A;  2OTX A;  1U5D A;  1U29 A;  1FGY A;  4K17 A;  2YT1 A;  2DYN A;  1UPR A;  3KZ1 A;  5HE2 A;  2QKL A;  5HE3 A;  1I7A A;  2Z0P A;  3PVU A;  2CY4 A;  2N0Y A;  5DIF B;  5J3T A;  1GG3 A;  1EVH A;  1KZG A;  2NMB A;  3D8E A;  1X1F A;  2VRW B;  4HAU B;  2M14 A;  3MDB C;  1ZSQ A;  2X18 A;  5FI0 A;  1H10 A;  1M7R A;  3PVW A;  3WYF B;  4DX8 A;  3T06 A;  3SO6 A;  1UEF A;  2L2I A;  4GN1 A;  3TFM A;  1FGZ A;  3FEH A;  4KHO A;  3U7D A;  4K2O A;  2MDX A;  5CLL B;  1OY2 A;  2L1C A;  5DI9 B;  2DX5 A;  4HAT B;  1K5G B;  3PEG A;  2KUP A;  2MKR A;  4HB0 B;  2I5C A;  5C5B B;  2K2J A;  3X23 A;  2GS0 A;  5C5B A;  4GZU A;  4MT7 A;  2LYD A;  4HB4 B;  4GXB A;  5D3Y A;  2ROV A;  2NZ8 B;  2CAY A;  4EKU A;  4WVF B;  5JP4 A;  4HAY B;  1XKE A;  4HB2 B;  1UPQ A;  3N7C A;  3PZD A;  1XCG A;  4CYE A;  1OQN A;  5JLJ B;  1V5U A;  2J0K A;  4NSW A;  1SHC A;  2VSZ A;  1P6S A;  1U5F A;  1ZM0 A;  2EC1 A;  2YS3 A;  3BIN A;  4HHV A;  5J3Y A;  5FI1 A;  3SUZ A;  1TJ6 A;  4DXA B;  1NU2 A;  2MWN B;  4A6K A;  1B55 A;  1V88 A;  4A6H A;  1X86 A;  4BBK A;  3DXC A;  3F0W A;  3A98 B;  2KGX B;  2YF0 A;  2K2U A;  1W1D A;  4TKN A;  4ZRJ A;  2LKO A;  3PSC A;  2YVC A;  3QWM A;  3D8D A;  2R09 A;  1WG7 A;  2D10 A;  3PP2 A;  2D11 A;  1FB8 A;  1H4R A;  4K81 A;  5CLQ B;  4KHA A;  1LB1 A;  3ODW A;  5LON B;  1MK9 B;  2DA0 A;  2Z0Q A;  1ZC3 B;  2RNR B;  2V76 A;  4Z2N A;  2GJY A;  1WJM A;  4TYZ A;  4WJ7 A;  4HAW B;  2P8V A;  4DX9 0;  3CXB B;  1W1G A;  1X1G A;  2H7E A;  4ZRI A;  3HW2 B;  2W2X C;  2DKP A;  5J3Q A;  4XWX A;  1PLS A;  1OMW A;  2QKM A;  3TCA A;  4EJN A;  3QBV B;  1GC6 A;  2EMS A;  4KHB B;  1BTK A;  1BWN A;  3DXD A;  1P3R A;  4Z2M B;  2ROZ B;  3LJU X;  4IOY X;  2COA A;  2RLO A;  4WSF A;  4KAX B;  1DYN A;  1V5M A;  2HTH B;  2UZS A;  2P0F A;  3DXE A;  4K2P A;  4YON A;  2MFQ A;  3IVF A;  3KRW A;  1NTV A;  4YL8 A;  4NY0 A;  2GCJ A;  3F5R A;  5D3W A;  3M1I B;  3P7Z A;  1EAZ A;  1M7E A;  3RCP A;  1KZ7 A;  1TXD A;  3GYO A;  1J0W A;  2DYQ A;  2J0M A;  3ML4 A;  1AQC A;  3TW1 A;  4A5K A;  2ZPY A;  2G35 A;  2LG1 A;  1U2B A;  4KVG B;  4DBB A;  4GMV A;  3VOQ A;  4B6H A;  1ZVR A;  4HB3 B;  3BJI A;  1FHO A;  1Y5O A;  1DDM A;  4ZRK A;  4F7U P;  1WGU A;  2W2X D;  4P7I A;  2LUL A;  2AL6 A;  2LOX A;  1LW3 A;  2YS1 A;  5KQ1 A;  5C79 A;  2RGN B;  3SNH A;  5DHA B;  3P6A A;  2I5F A;  2DLW A;  4PQ0 A;  3ULB A;  2COC A;  2YT0 A;  1N3H A;  1DRO A;  2DHI A;  4F7H A;  1WJ1 A;  4HAX B;  3D8F A;  3AU4 A;  3KSY A;  1MPH A;  1AWE A;  5JHG A;  2IYB A;  2D9X A;  5JHH A;  3O96 A;  2D9W A;  3ODO A;  1KI1 B;  3TO1 A;  3ZDT A;  5D3V A;  3U8Z A;  3QIJ A;  2DTC A;  2BCJ A;  3SYX A;  4H8S A;  1FHW A;  3FM8 C;  1XR0 B;  2HE7 A;  1WGQ A;  1FHX A;  1MKE A;  3V5W A;  1Z87 A;  2YS5 A;  4HAZ B;  2D9V A;  2DN6 A;  3NSU A;  2Y8F A;  2R0D A;  4MK0 A;  2KCJ A;  1DBH A;  4IFS A;  1J19 A;  2DHK A;  3PG7 A;  3SV1 A;  2ELA A;  1U5E A;  3OAN A;  3HK0 A;  3ULC A;  1Y19 B;  2RSG A;  2DX1 A;  1WVH A;  3A8Q A;  1MK7 B;  2ADZ A;  3KY9 A;  3PVL A;  3ODX A;  2E2X A;  1EGX A;  3AU5 A;  1E5W A;  2DHJ A;  1W1H A;  1SGH A;  1XD4 A;  2CRF A;  1U5G A;  1BTN A;  1NTY A;  3A8P A;  5C6R A;  4IAP A;  1WI1 A;  1ISN A;  5HE0 A;  1X05 A;  2RVB B;  2I1J A;  3GYP A;  1PFJ A;  1RRP B;  3VIA A;  1V61 A;  2CY5 A;  3MPX A;  5LOP B;  2OQB A;  2COF A;  1UNR A;  4F7G A;  1MIX A;  2D4Q A;  1X11 A;  4PNK A;  1BAK A;  2EJ8 A;  2DKQ A;  4GMX B;  1DDW A;  5D27 A;  2D9Y A;  2IFS A;  1IRS A;  2UZR A;  5KQ4 A;  2JP2 A;  4A6F B;  4D0N B;  4HAV B;  1PMS A;  4A6F A;  5EFX A;  1EF1 A;  2W2W A;  4HDO A;  2N23 A;  2AEH A;  2YSZ A;  1XX0 A;  1UNQ A;  3UZT A;  4GPT B;  2Y8G A;  2P0D A;  2VKI A;  1TQZ A;  3CIK A;  3FSS A;  2RUK B;  5DH9 B;  2Z0O A;  1FOE A;  2YRY A;  2J59 M;  1DDV A;  2XQN M;  2PZ1 A;  4L6E A;  1V89 A;  3HQC A;  5DHF B;  2K00 A;  1Q67 A;  2DFK A;  2Q13 A;  1UNP A;  1K5D B;  3TVV A; 
#chains in the Genus database with same CATH topology
 4Y94 A;  2LOZ A;  5GOW B;  5HE1 A;  4HDQ A;  5C16 A;  1XOD A;  2GUM A;  1I2H A;  4MY6 A;  1FAO A;  2D9Z A;  2I1K A;  2ELB A;  4CHM A;  5KCV A;  1QC6 A;  2P0H A;  4OT1 A;  4QJ5 B;  2COD A;  2J0J A;  1QQG A;  1MIZ B;  3G9W A;  2GCL A;  2ZKM X;  1RJ2 A;  2Y7B A;  5L81 A;  2D2Q A;  2FJL A;  2UVM A;  1U27 A;  1V5P A;  1NI2 A;  4C0A A;  3AJ4 A;  1MAI A;  4CHJ A;  3ZVR A;  1ZC4 B;  4EMO A;  1P5T A;  2H7D A;  2M38 A;  5D3X A;  2EMT A;  1GC7 A;  3WA0 A;  3KRX A;  2OTX A;  1U5D A;  1U29 A;  1FGY A;  4K17 A;  2YT1 A;  2DYN A;  1UPR A;  3KZ1 A;  5HE2 A;  2QKL A;  5HE3 A;  1I7A A;  2Z0P A;  3PVU A;  2CY4 A;  2N0Y A;  5DIF B;  5J3T A;  1GG3 A;  1EVH A;  1KZG A;  2NMB A;  3D8E A;  1X1F A;  2VRW B;  4HAU B;  2M14 A;  3MDB C;  1ZSQ A;  2X18 A;  5FI0 A;  1H10 A;  1M7R A;  3PVW A;  3WYF B;  4DX8 A;  3T06 A;  3SO6 A;  1UEF A;  3DCX A;  2RRF A;  4QXA B;  2L2I A;  4GN1 A;  3FVC A;  3TFM A;  1MI1 A;  1FGZ A;  3FEH A;  4KHO A;  3U7D A;  4K2O A;  2MDX A;  5CLL B;  4QJ3 B;  1OY2 A;  2L1C A;  5DI9 B;  2DX5 A;  4HAT B;  1K5G B;  3PEG A;  2KUP A;  2MKR A;  4HB0 B;  2I5C A;  5C5B B;  4HSI A;  2K2J A;  3X23 A;  2GS0 A;  5C5B A;  4GZU A;  4MT7 A;  2LYD A;  4HB4 B;  4CSQ A;  4GXB A;  5D3Y A;  2ROV A;  2NZ8 B;  2Z4D A;  2CAY A;  4EKU A;  4OSN A;  4WVF B;  3NW8 A;  5JP4 A;  4HAY B;  1XKE A;  4HB2 B;  1UPQ A;  3N7C A;  3PZD A;  1XCG A;  4CYE A;  1OQN A;  5JLJ B;  1V5U A;  2J0K A;  4NSW A;  1SHC A;  2VSZ A;  1P6S A;  1U5F A;  1ZM0 A;  2EC1 A;  2YS3 A;  3BIN A;  4HHV A;  5J3Y A;  5FI1 A;  3SUZ A;  1TJ6 A;  3U12 A;  4DXA B;  1NU2 A;  2MWN B;  4A6K A;  5I2S A;  1B55 A;  1V88 A;  4A6H A;  1X86 A;  4BBK A;  3DXC A;  3F0W A;  3A98 B;  2KGX B;  2YF0 A;  2K2U A;  3HIE A;  1W1D A;  4TKN A;  4ZRJ A;  2LKO A;  3PSC A;  2YVC A;  3B77 A;  3QWM A;  4GNK B;  3D8D A;  2R09 A;  1WG7 A;  2D10 A;  3PP2 A;  2D11 A;  1FB8 A;  1H4R A;  4K81 A;  5CLQ B;  4KHA A;  1LB1 A;  3ODW A;  5LON B;  1MK9 B;  2DA0 A;  2Z0Q A;  1ZC3 B;  2RNR B;  2V76 A;  2FJU B;  4Z2N A;  2GJY A;  1WJM A;  4TYZ A;  4WJ7 A;  4HAW B;  2P8V A;  4DX9 0;  3CXB B;  1W1G A;  1X1G A;  2H7E A;  4ZRI A;  3HW2 B;  2W2X C;  2DKP A;  2K8E A;  5J3Q A;  4XWX A;  2Z13 A;  1PLS A;  1OMW A;  2KUQ A;  2QKM A;  3TCA A;  4EJN A;  3QBV B;  1GC6 A;  2EMS A;  4KHB B;  1BTK A;  1BWN A;  2YT2 A;  3DXD A;  3HSA A;  1P3R A;  4KHB A;  4Z2M B;  2ROZ B;  3LJU X;  4IOY X;  2COA A;  2RLO A;  4WSF A;  4KAX B;  1DYN A;  1V5M A;  2HTH B;  2UZS A;  3A58 A;  2P0F A;  3DXE A;  4K2P A;  4QJ4 B;  1ZYI A;  4YON A;  2MFQ A;  3IVF A;  3KRW A;  1NTV A;  4YL8 A;  4NY0 A;  2GCJ A;  3F5R A;  5D3W A;  3M1I B;  3P7Z A;  1EAZ A;  1M7E A;  3RCP A;  2KR0 A;  3OHM B;  1KZ7 A;  1TXD A;  1T77 A;  3GYO A;  2KIG A;  1J0W A;  2DYQ A;  2J0M A;  3ML4 A;  1AQC A;  3TW1 A;  4A5K A;  2ZPY A;  2G35 A;  2LG1 A;  1U2B A;  4KVG B;  4DBB A;  4GMV A;  3VOQ A;  4B6H A;  1ZVR A;  4HB3 B;  3BJI A;  1FHO A;  3NWF A;  1Y5O A;  1DDM A;  4ZRK A;  4F7U P;  1WGU A;  2W2X D;  4P7I A;  2LUL A;  2AL6 A;  2LOX A;  1LW3 A;  2YS1 A;  5KQ1 A;  5C79 A;  2RGN B;  3SNH A;  2Z59 A;  5DHA B;  3P6A A;  2I5F A;  2DLW A;  4PQ0 A;  3ULB A;  2COC A;  2YT0 A;  1N3H A;  1DRO A;  2DHI A;  3NWD A;  4F7H A;  1WJ1 A;  4HAX B;  3D8F A;  3AU4 A;  3KSY A;  1MPH A;  1AWE A;  5JHG A;  2IYB A;  2D9X A;  5JHH A;  3O96 A;  2K49 A;  2D9W A;  3ODO A;  1KI1 B;  3TO1 A;  3ZDT A;  5D3V A;  3U8Z A;  3QIJ A;  2DTC A;  2BCJ A;  3SYX A;  4H8S A;  1FHW A;  3FM8 C;  1XR0 B;  2HE7 A;  1WGQ A;  1FHX A;  1MKE A;  3V5W A;  1Z87 A;  2YS5 A;  4HAZ B;  2D9V A;  2DN6 A;  3NSU A;  2Y8F A;  3NWA A;  2R0D A;  4MK0 A;  2KCJ A;  1DBH A;  4IFS A;  1J19 A;  2DHK A;  3PG7 A;  3SV1 A;  2ELA A;  1U5E A;  3OAN A;  3HK0 A;  3ULC A;  4DIX A;  2Z14 A;  1Y19 B;  2RSG A;  2DX1 A;  1WVH A;  3A8Q A;  1MK7 B;  2ADZ A;  3KY9 A;  3PVL A;  3ODX A;  2E2X A;  1EGX A;  3AU5 A;  1E5W A;  2DHJ A;  1W1H A;  1SGH A;  1XD4 A;  2CRF A;  1U5G A;  4GOU A;  1BTN A;  1NTY A;  3A8P A;  5C6R A;  4IAP A;  1WI1 A;  1ISN A;  2NBV A;  5HE0 A;  1X05 A;  5LG4 B;  2RVB B;  2I1J A;  3GYP A;  1PFJ A;  1RRP B;  3VIA A;  1V61 A;  2CY5 A;  3MPX A;  5LOP B;  2OQB A;  2COF A;  1UNR A;  4F7G A;  1MIX A;  2D4Q A;  1X11 A;  4PNK A;  1BAK A;  2EJ8 A;  2DKQ A;  4GMX B;  1DDW A;  5M4Y B;  5D27 A;  2D9Y A;  2IFS A;  1IRS A;  2UZR A;  5KQ4 A;  2JP2 A;  2KIE A;  4A6F B;  4D0N B;  4HAV B;  1PMS A;  2R2Y A;  4A6F A;  5EFX A;  1EF1 A;  2W2W A;  4HDO A;  2N23 A;  2AEH A;  2YSZ A;  5IRS A;  1XX0 A;  4D6W A;  1UNQ A;  3UZT A;  4GPT B;  2Y8G A;  2P0D A;  2VKI A;  1TQZ A;  3CIK A;  3FSS A;  2RUK B;  5DH9 B;  2Z0O A;  1FOE A;  2YRY A;  2J59 M;  1DDV A;  2XQN M;  2PZ1 A;  4L6E A;  1V89 A;  4L1R A;  3HQC A;  5DHF B;  2K00 A;  5I2M A;  1Q67 A;  2DFK A;  2Q13 A;  1UNP A;  1K5D B;  3TVV A; 
#chains in the Genus database with same CATH homology
 4Y94 A;  2LOZ A;  5GOW B;  5HE1 A;  4HDQ A;  5C16 A;  1XOD A;  1I2H A;  4MY6 A;  1FAO A;  2D9Z A;  2I1K A;  2ELB A;  4CHM A;  5KCV A;  1QC6 A;  2P0H A;  2COD A;  2J0J A;  1QQG A;  1MIZ B;  3G9W A;  2GCL A;  1RJ2 A;  2Y7B A;  5L81 A;  2D2Q A;  2FJL A;  2UVM A;  1U27 A;  1V5P A;  1NI2 A;  4C0A A;  3AJ4 A;  1MAI A;  4CHJ A;  3ZVR A;  1ZC4 B;  4EMO A;  1P5T A;  2H7D A;  2M38 A;  5D3X A;  2EMT A;  1GC7 A;  3WA0 A;  3KRX A;  2OTX A;  1U5D A;  1U29 A;  1FGY A;  4K17 A;  2YT1 A;  2DYN A;  1UPR A;  3KZ1 A;  5HE2 A;  2QKL A;  5HE3 A;  1I7A A;  2Z0P A;  3PVU A;  2CY4 A;  2N0Y A;  5DIF B;  5J3T A;  1GG3 A;  1EVH A;  1KZG A;  2NMB A;  3D8E A;  1X1F A;  2VRW B;  4HAU B;  2M14 A;  3MDB C;  1ZSQ A;  2X18 A;  5FI0 A;  1H10 A;  1M7R A;  3PVW A;  3WYF B;  4DX8 A;  3T06 A;  3SO6 A;  1UEF A;  2L2I A;  4GN1 A;  3TFM A;  1FGZ A;  3FEH A;  4KHO A;  3U7D A;  4K2O A;  2MDX A;  5CLL B;  1OY2 A;  2L1C A;  5DI9 B;  2DX5 A;  4HAT B;  1K5G B;  3PEG A;  2KUP A;  2MKR A;  4HB0 B;  2I5C A;  5C5B B;  2K2J A;  3X23 A;  2GS0 A;  5C5B A;  4GZU A;  4MT7 A;  2LYD A;  4HB4 B;  4GXB A;  5D3Y A;  2ROV A;  2NZ8 B;  2CAY A;  4EKU A;  4WVF B;  5JP4 A;  4HAY B;  1XKE A;  4HB2 B;  1UPQ A;  3N7C A;  3PZD A;  1XCG A;  4CYE A;  1OQN A;  5JLJ B;  1V5U A;  2J0K A;  4NSW A;  1SHC A;  2VSZ A;  1P6S A;  1U5F A;  1ZM0 A;  2EC1 A;  2YS3 A;  3BIN A;  4HHV A;  5J3Y A;  5FI1 A;  3SUZ A;  1TJ6 A;  4DXA B;  1NU2 A;  2MWN B;  4A6K A;  1B55 A;  1V88 A;  4A6H A;  1X86 A;  4BBK A;  3DXC A;  3F0W A;  3A98 B;  2KGX B;  2YF0 A;  2K2U A;  1W1D A;  4TKN A;  4ZRJ A;  2LKO A;  3PSC A;  2YVC A;  3QWM A;  3D8D A;  2R09 A;  1WG7 A;  2D10 A;  3PP2 A;  2D11 A;  1FB8 A;  1H4R A;  4K81 A;  5CLQ B;  4KHA A;  1LB1 A;  3ODW A;  5LON B;  1MK9 B;  2DA0 A;  2Z0Q A;  1ZC3 B;  2RNR B;  2V76 A;  4Z2N A;  2GJY A;  1WJM A;  4TYZ A;  4WJ7 A;  4HAW B;  2P8V A;  4DX9 0;  3CXB B;  1W1G A;  1X1G A;  2H7E A;  4ZRI A;  3HW2 B;  2W2X C;  2DKP A;  5J3Q A;  4XWX A;  1PLS A;  1OMW A;  2QKM A;  3TCA A;  4EJN A;  3QBV B;  1GC6 A;  2EMS A;  4KHB B;  1BTK A;  1BWN A;  3DXD A;  1P3R A;  4Z2M B;  2ROZ B;  3LJU X;  4IOY X;  2COA A;  2RLO A;  4WSF A;  4KAX B;  1DYN A;  1V5M A;  2HTH B;  2UZS A;  2P0F A;  3DXE A;  4K2P A;  4YON A;  2MFQ A;  3IVF A;  3KRW A;  1NTV A;  4YL8 A;  4NY0 A;  2GCJ A;  3F5R A;  5D3W A;  3M1I B;  3P7Z A;  1EAZ A;  1M7E A;  3RCP A;  1KZ7 A;  1TXD A;  3GYO A;  1J0W A;  2DYQ A;  2J0M A;  3ML4 A;  1AQC A;  3TW1 A;  4A5K A;  2ZPY A;  2G35 A;  2LG1 A;  1U2B A;  4KVG B;  4DBB A;  4GMV A;  3VOQ A;  4B6H A;  1ZVR A;  4HB3 B;  3BJI A;  1FHO A;  1Y5O A;  1DDM A;  4ZRK A;  4F7U P;  1WGU A;  2W2X D;  4P7I A;  2LUL A;  2AL6 A;  2LOX A;  1LW3 A;  2YS1 A;  5KQ1 A;  5C79 A;  2RGN B;  3SNH A;  5DHA B;  3P6A A;  2I5F A;  2DLW A;  4PQ0 A;  3ULB A;  2COC A;  2YT0 A;  1N3H A;  1DRO A;  2DHI A;  4F7H A;  1WJ1 A;  4HAX B;  3D8F A;  3AU4 A;  3KSY A;  1MPH A;  1AWE A;  5JHG A;  2IYB A;  2D9X A;  5JHH A;  3O96 A;  2D9W A;  3ODO A;  1KI1 B;  3TO1 A;  3ZDT A;  5D3V A;  3U8Z A;  3QIJ A;  2DTC A;  2BCJ A;  3SYX A;  4H8S A;  1FHW A;  3FM8 C;  1XR0 B;  2HE7 A;  1WGQ A;  1FHX A;  1MKE A;  3V5W A;  1Z87 A;  2YS5 A;  4HAZ B;  2D9V A;  2DN6 A;  3NSU A;  2Y8F A;  2R0D A;  4MK0 A;  2KCJ A;  1DBH A;  4IFS A;  1J19 A;  2DHK A;  3PG7 A;  3SV1 A;  2ELA A;  1U5E A;  3OAN A;  3HK0 A;  3ULC A;  1Y19 B;  2RSG A;  2DX1 A;  1WVH A;  3A8Q A;  1MK7 B;  2ADZ A;  3KY9 A;  3PVL A;  3ODX A;  2E2X A;  1EGX A;  3AU5 A;  1E5W A;  2DHJ A;  1W1H A;  1SGH A;  1XD4 A;  2CRF A;  1U5G A;  1BTN A;  1NTY A;  3A8P A;  5C6R A;  4IAP A;  1WI1 A;  1ISN A;  5HE0 A;  1X05 A;  2RVB B;  2I1J A;  3GYP A;  1PFJ A;  1RRP B;  3VIA A;  1V61 A;  2CY5 A;  3MPX A;  5LOP B;  2OQB A;  2COF A;  1UNR A;  4F7G A;  1MIX A;  2D4Q A;  1X11 A;  4PNK A;  1BAK A;  2EJ8 A;  2DKQ A;  4GMX B;  1DDW A;  5D27 A;  2D9Y A;  2IFS A;  1IRS A;  2UZR A;  5KQ4 A;  2JP2 A;  4A6F B;  4D0N B;  4HAV B;  1PMS A;  4A6F A;  5EFX A;  1EF1 A;  2W2W A;  4HDO A;  2N23 A;  2AEH A;  2YSZ A;  1XX0 A;  1UNQ A;  3UZT A;  4GPT B;  2Y8G A;  2P0D A;  2VKI A;  1TQZ A;  3CIK A;  3FSS A;  2RUK B;  5DH9 B;  2Z0O A;  1FOE A;  2YRY A;  2J59 M;  1DDV A;  2XQN M;  2PZ1 A;  4L6E A;  1V89 A;  3HQC A;  5DHF B;  2K00 A;  1Q67 A;  2DFK A;  2Q13 A;  1UNP A;  1K5D B;  3TVV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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