1FB8A

Structure of the pleckstrin homology domain from dapp1/phish
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
106
structure length
106
Chain Sequence
LVPTAPSLGTKEGYLTKQGGLVKTWKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLCAKTGVEADEWIKILRWKLSQIR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords DUAL ADAPTOR OF PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDES
total genus 20
structure length 106
sequence length 106
ec nomenclature
pdb deposition date 2000-07-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1fb8A00
1OY2A 5FI0A 2YSZA 4PNKA 2LYDA 2GJYA 2ADZA 4ZRIA 2J0JA 5KQ1A 1DBHA 4F7UP 3ULCA 2LULA 4A6HA 2Z0QA 1GG3A 1BTKA 4K81A 2LG1A 2YRYA 2OTXA 1FGYA 2DLWA 4GN1A 1FB8A 2Y7BA 3FM8C 4CYEA 2NMBA 1FOEA 2R09A 4EKUA 2D2QA 1UNPA 4HB0B 4A6FB 3GYPA 1DDWA 4WJ7A 2V76A 1FHXA 2CAYA 4GPTB 1BWNA 3T06A 1GC6A 1H4RA 2YF0A 1WGQA 1XR0B 4KAXB 5EFXA 1BAKA 2BCJA 2K00A 2RUKB 2Z0OA 2NZ8B 2AEHA 2EMTA 3ULBA 3PVUA 2RSGA 3DXDA 4HB4B 1EVHA 4CHJA 1ZM0A 3ODOA 5C5BB 4Y94A 4D0NB 4HAYB 4MK0A 2Y8GA 3SNHA 2DN6A 3WA0A 4A6KA 1TXDA 2CY5A 4GZUA 2RLOA 4GXBA 2ZPYA 3KY9A 1V5PA 4HAZB 2YS5A 1SHCA 2EC1A 2J0KA 3OANA 3ODXA 2YT1A 2E2XA 2D9ZA 1U5FA 1V5MA 3HQCA 3PVWA 5DH9B 4EJNA 2MDXA 1P3RA 2D9WA 4B6HA 3KRXA 1OMWA 1WVHA 1WI1A 5GOWB 1LB1A 2DHJA 2D9VA 2RNRB 2Q13A 1DDMA 2MWNB 3ZVRA 1X1GA 1ZC4B 2H7DA 5J3QA 5DHAB 1EGXA 3QBVB 4XWXA 2OQBA 5HE3A 4Z2NA 5J3YA 1MIXA 2L1CA 2DKQA 1E5WA 1MPHA 2EJ8A 5JHGA 2EMSA 4K2OA 3NSUA 2W2XD 4IOYX 4BBKA 2XQNM 2DHKA 4WVFB 2ROVA 1ZVRA 2I1KA 4HB2B 3WYFB 1WGUA 2D11A 1H10A 2J59M 3DXEA 2ELAA 1RJ2A 4A5KA 4DBBA 4ZRKA 4YL8A 2HTHB 3SYXA 1I7AA 2VRWB 3GYOA 4L6EA 3M1IB 1DYNA 5KCVA 1TJ6A 2YS1A 2IFSA 1AQCA 1I2HA 5D3XA 5C5BA 5FI1A 2M14A 2LOXA 2MKRA 5C16A 1AWEA 2GCLA 4YONA 4EMOA 1U5GA 2CY4A 2DYNA 2RGNB 4KHBB 5L81A 1Y5OA 2PZ1A 1J0WA 4P7IA 1UPRA 1XCGA 4F7GA 3KZ1A 3MDBC 4ZRJA 1RRPB 1ISNA 2G35A 1MK9B 3LJUX 3BINA 2YT0A 2DA0A 1W1DA 4C0AA 1XODA 1KZ7A 3QIJA 1FGZA 1Q67A 1X1FA 3QWMA 1MKEA 1UNRA 5JHHA 2GS0A 4HHVA 2DHIA 5CLLB 2W2WA 1M7RA 3N7CA 3X23A 3SV1A 1NTVA 3KSYA 3O96A 1UPQA 3TFMA 3A98B 5JP4A 2D10A 4KVGB 3A8QA 4K17A 4IAPA 2RVBB 4HDOA 3HW2B 1MK7B 2Y8FA 1OQNA 3TCAA 3D8FA 1PLSA 3TW1A 3A8PA 1FHWA 4Z2MB 1XD4A 2VKIA 1TQZA 1V5UA 3VOQA 1SGHA 3RCPA 5HE2A 2IYBA 2MFQA 4HAWB 2R0DA 3ML4A 1EF1A 1EAZA 4A6FA 1UEFA 1NTYA 1XX0A 1Z87A 2ROZB 1DROA 2P0DA 1N3HA 2QKLA 2N0YA 2DFKA 3P6AA 2QKMA 1DDVA 1K5GB 1B55A 2DYQA 1IRSA 1J19A 2CRFA 2COFA 3DXCA 5KQ4A 4GMVA 1U5DA 4PQ0A 4HAVB 1W1GA 2YS3A 3TVVA 3SO6A 2UVMA 5J3TA 3SUZA 3F5RA 2I5CA 4F7HA 2CODA 2COAA 5D3VA 2LOZA 4KHAA 1U29A 1NU2A 3F0WA 1K5DB 5D3WA 1P6SA 4TYZA 4GMXB 1QC6A 3AU5A 3FSSA 2P8VA 4HAXB 5DIFB 3CXBB 3MPXA 5LOPB 1M7EA 5JLJB 2KCJA 5HE0A 2KUPA 5D3YA 3VIAA 1NI2A 4HDQA 4HATB 2ELBA 5DHFB 2DX5A 1W1HA 2H7EA 1ZSQA 2YVCA 3PVLA 4WSFA 2K2UA 2KGXB 2D9XA 1UNQA 3PZDA 1Y19B 3AU4A 2L2IA 4CHMA 4TKNA 3U7DA 1GC7A 3ZDTA 3HK0A 1QQGA 2P0HA 2P0FA 4KHOA 1WJ1A 3PSCA 3PG7A 5HE1A 2LKOA 4NSWA 1U2BA 2J0MA 2GCJA 1KI1B 2Z0PA 3BJIA 3U8ZA 4K2PA 2K2JA 1MAIA 4DXAB 1FHOA 5LONB 2D4QA 2N23A 1MIZB 2FJLA 1KZGA 3AJ4A 3UZTA 4DX8A 5D27A 3D8DA 5DI9B 3TO1A 1X11A 2I1JA 3V5WA 2X18A 1PFJA 4HAUB 4H8SA 1WG7A 4DX90 1U27A 1V89A 2AL6A 2UZRA 3P7ZA 4IFSA 2DKPA 1X86A 2DX1A 4NY0A 1V88A 2D9YA 2W2XC 1V61A 2UZSA 2COCA 1ZC3B 5C79A 5CLQB 1FAOA 1U5EA 5C6RA 2VSZA 3G9WA 3FEHA 1P5TA 1X05A 2HE7A 2DTCA 2M38A 3PEGA 1WJMA 2JP2A 1PMSA 1BTNA 3KRWA 2I5FA 4HB3B 3IVFA 4MY6A 3PP2A 1LW3A 3ODWA 3D8EA 3CIKA 1XKEA 4MT7A
chains in the Genus database with same CATH superfamily
4KHBA 1OY2A 5FI0A 2YSZA 4PNKA 2LYDA 2GJYA 2ADZA 4ZRIA 2J0JA 5KQ1A 1DBHA 4F7UP 3ULCA 2LULA 4A6HA 2Z0QA 1GG3A 1BTKA 4K81A 2LG1A 2YRYA 2OTXA 1FGYA 2DLWA 4GN1A 1FB8A 2Y7BA 3FM8C 4CYEA 2NMBA 2KR0A 1FOEA 2R09A 4EKUA 2D2QA 1UNPA 4GOUA 4HB0B 3GYPA 4A6FB 1DDWA 4WJ7A 2V76A 1FHXA 2CAYA 4GPTB 1BWNA 3T06A 1GC6A 1H4RA 1ZYIA 2YF0A 1WGQA 1XR0B 4KAXB 5EFXA 1BAKA 2BCJA 2K00A 2RUKB 2Z0OA 2NZ8B 2AEHA 2EMTA 3ULBA 3PVUA 2RSGA 3DXDA 4HB4B 1EVHA 4CHJA 1ZM0A 3ODOA 5C5BB 4Y94A 4D0NB 4HAYB 4MK0A 2Y8GA 3SNHA 2DN6A 3WA0A 4A6KA 1TXDA 2CY5A 4GZUA 2KUQA 2RLOA 4GXBA 2ZPYA 3KY9A 1V5PA 4HAZB 2YS5A 1SHCA 2EC1A 2J0KA 3OANA 3ODXA 2YT1A 2E2XA 2NBVA 2D9ZA 1U5FA 1V5MA 3HQCA 3PVWA 5DH9B 4EJNA 2MDXA 1P3RA 2D9WA 4B6HA 3KRXA 1OMWA 1WVHA 1WI1A 5GOWB 4QJ5B 1LB1A 2DHJA 2D9VA 2RNRB 2Q13A 1DDMA 2MWNB 3ZVRA 1X1GA 1ZC4B 2H7DA 5J3QA 5DHAB 1EGXA 3QBVB 4XWXA 2OQBA 5HE3A 4Z2NA 5J3YA 1MIXA 2L1CA 2DKQA 1E5WA 1MPHA 2EJ8A 5JHGA 2EMSA 4K2OA 3NSUA 2W2XD 4IOYX 4BBKA 2XQNM 2DHKA 4WVFB 2ROVA 1ZVRA 2I1KA 4HB2B 3WYFB 1WGUA 2D11A 1H10A 2J59M 4QXAB 3DXEA 2ELAA 1RJ2A 4A5KA 4DBBA 4ZRKA 4YL8A 2HTHB 3SYXA 1I7AA 2VRWB 3GYOA 4L6EA 3M1IB 1DYNA 5KCVA 1TJ6A 2YS1A 2IFSA 1AQCA 1I2HA 5D3XA 5C5BA 5FI1A 2M14A 2LOXA 2MKRA 5C16A 1AWEA 2GCLA 4YONA 4QJ4B 4EMOA 5I2SA 1U5GA 2CY4A 2DYNA 2RGNB 4KHBB 5L81A 1Y5OA 2PZ1A 1J0WA 4P7IA 1UPRA 1XCGA 4F7GA 2Z59A 3KZ1A 3MDBC 4ZRJA 1RRPB 2Z13A 4DIXA 3U12A 1ISNA 2G35A 4QJ3B 1MK9B 3LJUX 3BINA 2YT0A 2DA0A 1W1DA 4C0AA 1XODA 1KZ7A 3QIJA 1FGZA 1MI1A 1Q67A 3HIEA 4OSNA 3FVCA 1X1FA 5IRSA 3QWMA 1MKEA 1UNRA 5JHHA 2GS0A 2GUMA 4HHVA 2ZKMX 2K8EA 2DHIA 5CLLB 2W2WA 1M7RA 2RRFA 3N7CA 2Z14A 3X23A 3SV1A 4OT1A 1NTVA 3KSYA 3O96A 1UPQA 3TFMA 3A98B 5JP4A 2D10A 4KVGB 5I2MA 3A8QA 4K17A 2YT2A 4IAPA 2RVBB 4HDOA 3HW2B 1MK7B 2KIGA 2Y8FA 1OQNA 4HSIA 3TCAA 3D8FA 2R2YA 1PLSA 3TW1A 3A8PA 1FHWA 4Z2MB 1XD4A 2VKIA 3NWDA 2K49A 2FJUB 3NW8A 4CSQA 1TQZA 1V5UA 3VOQA 1SGHA 3RCPA 5HE2A 2IYBA 2MFQA 4HAWB 2R0DA 3ML4A 1EF1A 1EAZA 4A6FA 1UEFA 1NTYA 1XX0A 1Z87A 2ROZB 1DROA 2P0DA 1N3HA 2QKLA 2N0YA 2DFKA 3P6AA 2QKMA 1DDVA 1K5GB 1B55A 2DYQA 1IRSA 1J19A 2CRFA 2COFA 3DXCA 5KQ4A 3HSAA 4GMVA 1U5DA 4PQ0A 4HAVB 1W1GA 2YS3A 3TVVA 3SO6A 2UVMA 5J3TA 3SUZA 3F5RA 2I5CA 4F7HA 2CODA 2COAA 5D3VA 2Z4DA 2LOZA 4KHAA 1U29A 1NU2A 3F0WA 1K5DB 5D3WA 1P6SA 4TYZA 4GMXB 1QC6A 3AU5A 3FSSA 2P8VA 4HAXB 5DIFB 3CXBB 3MPXA 5LOPB 1M7EA 5JLJB 4GNKB 4L1RA 2KCJA 5HE0A 2KUPA 5D3YA 3VIAA 1NI2A 4HDQA 4HATB 2ELBA 5DHFB 2DX5A 1W1HA 2H7EA 1ZSQA 2YVCA 3PVLA 4WSFA 2K2UA 2KGXB 2D9XA 1UNQA 3PZDA 1Y19B 3AU4A 2L2IA 4D6WA 4CHMA 4TKNA 3U7DA 1GC7A 3ZDTA 3HK0A 1QQGA 2P0HA 2P0FA 4KHOA 1WJ1A 3PSCA 3PG7A 5HE1A 2LKOA 4NSWA 1U2BA 2J0MA 2GCJA 1KI1B 2Z0PA 3BJIA 3U8ZA 4K2PA 2K2JA 1MAIA 4DXAB 1FHOA 2KIEA 5LONB 2D4QA 2N23A 1MIZB 2FJLA 1KZGA 3AJ4A 3UZTA 4DX8A 5D27A 3D8DA 5DI9B 3TO1A 1X11A 2I1JA 3V5WA 2X18A 1PFJA 4HAUB 1T77A 4H8SA 1WG7A 4DX90 1U27A 1V89A 2AL6A 2UZRA 3P7ZA 4IFSA 2DKPA 1X86A 2DX1A 4NY0A 1V88A 2D9YA 2W2XC 3B77A 1V61A 3OHMB 2UZSA 2COCA 1ZC3B 5C79A 5CLQB 1FAOA 1U5EA 5C6RA 3DCXA 2VSZA 3G9WA 3FEHA 1P5TA 1X05A 2HE7A 2DTCA 2M38A 3NWAA 3PEGA 5LG4B 1WJMA 2JP2A 1PMSA 1BTNA 3NWFA 5M4YB 3KRWA 2I5FA 4HB3B 3IVFA 4MY6A 3PP2A 1LW3A 3ODWA 3D8EA 3CIKA 3A58A 1XKEA 4MT7A
chains in the Genus database with same CATH topology
1OY2A 5FI0A 2YSZA 4PNKA 2LYDA 2GJYA 2ADZA 4ZRIA 2J0JA 5KQ1A 1DBHA 4F7UP 3ULCA 2LULA 4A6HA 2Z0QA 1GG3A 1BTKA 4K81A 2LG1A 2YRYA 2OTXA 1FGYA 2DLWA 4GN1A 1FB8A 2Y7BA 3FM8C 4CYEA 2NMBA 1FOEA 2R09A 4EKUA 2D2QA 1UNPA 4HB0B 4A6FB 3GYPA 1DDWA 4WJ7A 2V76A 1FHXA 2CAYA 4GPTB 1BWNA 3T06A 1GC6A 1H4RA 2YF0A 1WGQA 1XR0B 4KAXB 5EFXA 1BAKA 2BCJA 2K00A 2RUKB 2Z0OA 2NZ8B 2AEHA 2EMTA 3ULBA 3PVUA 2RSGA 3DXDA 4HB4B 1EVHA 4CHJA 1ZM0A 3ODOA 5C5BB 4Y94A 4D0NB 4HAYB 4MK0A 2Y8GA 3SNHA 2DN6A 3WA0A 4A6KA 1TXDA 2CY5A 4GZUA 2RLOA 4GXBA 2ZPYA 3KY9A 1V5PA 4HAZB 2YS5A 1SHCA 2EC1A 2J0KA 3OANA 3ODXA 2YT1A 2E2XA 2D9ZA 1U5FA 1V5MA 3HQCA 3PVWA 5DH9B 4EJNA 2MDXA 1P3RA 2D9WA 4B6HA 3KRXA 1OMWA 1WVHA 1WI1A 5GOWB 1LB1A 2DHJA 2D9VA 2RNRB 2Q13A 1DDMA 2MWNB 3ZVRA 1X1GA 1ZC4B 2H7DA 5J3QA 5DHAB 1EGXA 3QBVB 4XWXA 2OQBA 5HE3A 4Z2NA 5J3YA 1MIXA 2L1CA 2DKQA 1E5WA 1MPHA 2EJ8A 5JHGA 2EMSA 4K2OA 3NSUA 2W2XD 4IOYX 4BBKA 2XQNM 2DHKA 4WVFB 2ROVA 1ZVRA 2I1KA 4HB2B 3WYFB 1WGUA 2D11A 1H10A 2J59M 3DXEA 2ELAA 1RJ2A 4A5KA 4DBBA 4ZRKA 4YL8A 2HTHB 3SYXA 1I7AA 2VRWB 3GYOA 4L6EA 3M1IB 1DYNA 5KCVA 1TJ6A 2YS1A 2IFSA 1AQCA 1I2HA 5D3XA 5C5BA 5FI1A 2M14A 2LOXA 2MKRA 5C16A 1AWEA 2GCLA 4YONA 4EMOA 1U5GA 2CY4A 2DYNA 2RGNB 4KHBB 5L81A 1Y5OA 2PZ1A 1J0WA 4P7IA 1UPRA 1XCGA 4F7GA 3KZ1A 3MDBC 4ZRJA 1RRPB 1ISNA 2G35A 1MK9B 3LJUX 3BINA 2YT0A 2DA0A 1W1DA 4C0AA 1XODA 1KZ7A 3QIJA 1FGZA 1Q67A 1X1FA 3QWMA 1MKEA 1UNRA 5JHHA 2GS0A 4HHVA 2DHIA 5CLLB 2W2WA 1M7RA 3N7CA 3X23A 3SV1A 1NTVA 3KSYA 3O96A 1UPQA 3TFMA 3A98B 5JP4A 2D10A 4KVGB 3A8QA 4K17A 4IAPA 2RVBB 4HDOA 3HW2B 1MK7B 2Y8FA 1OQNA 3TCAA 3D8FA 1PLSA 3TW1A 3A8PA 1FHWA 4Z2MB 1XD4A 2VKIA 1TQZA 1V5UA 3VOQA 1SGHA 3RCPA 5HE2A 2IYBA 2MFQA 4HAWB 2R0DA 3ML4A 1EF1A 1EAZA 4A6FA 1UEFA 1NTYA 1XX0A 1Z87A 2ROZB 1DROA 2P0DA 1N3HA 2QKLA 2N0YA 2DFKA 3P6AA 2QKMA 1DDVA 1K5GB 1B55A 2DYQA 1IRSA 1J19A 2CRFA 2COFA 3DXCA 5KQ4A 4GMVA 1U5DA 4PQ0A 4HAVB 1W1GA 2YS3A 3TVVA 3SO6A 2UVMA 5J3TA 3SUZA 3F5RA 2I5CA 4F7HA 2CODA 2COAA 5D3VA 2LOZA 4KHAA 1U29A 1NU2A 3F0WA 1K5DB 5D3WA 1P6SA 4TYZA 4GMXB 1QC6A 3AU5A 3FSSA 2P8VA 4HAXB 5DIFB 3CXBB 3MPXA 5LOPB 1M7EA 5JLJB 2KCJA 5HE0A 2KUPA 5D3YA 3VIAA 1NI2A 4HDQA 4HATB 2ELBA 5DHFB 2DX5A 1W1HA 2H7EA 1ZSQA 2YVCA 3PVLA 4WSFA 2K2UA 2KGXB 2D9XA 1UNQA 3PZDA 1Y19B 3AU4A 2L2IA 4CHMA 4TKNA 3U7DA 1GC7A 3ZDTA 3HK0A 1QQGA 2P0HA 2P0FA 4KHOA 1WJ1A 3PSCA 3PG7A 5HE1A 2LKOA 4NSWA 1U2BA 2J0MA 2GCJA 1KI1B 2Z0PA 3BJIA 3U8ZA 4K2PA 2K2JA 1MAIA 4DXAB 1FHOA 5LONB 2D4QA 2N23A 1MIZB 2FJLA 1KZGA 3AJ4A 3UZTA 4DX8A 5D27A 3D8DA 5DI9B 3TO1A 1X11A 2I1JA 3V5WA 2X18A 1PFJA 4HAUB 4H8SA 1WG7A 4DX90 1U27A 1V89A 2AL6A 2UZRA 3P7ZA 4IFSA 2DKPA 1X86A 2DX1A 4NY0A 1V88A 2D9YA 2W2XC 1V61A 2UZSA 2COCA 1ZC3B 5C79A 5CLQB 1FAOA 1U5EA 5C6RA 2VSZA 3G9WA 3FEHA 1P5TA 1X05A 2HE7A 2DTCA 2M38A 3PEGA 1WJMA 2JP2A 1PMSA 1BTNA 3KRWA 2I5FA 4HB3B 3IVFA 4MY6A 3PP2A 1LW3A 3ODWA 3D8EA 3CIKA 1XKEA 4MT7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OY2 A;  5FI0 A;  2YSZ A;  4PNK A;  2LYD A;  2GJY A;  2ADZ A;  4ZRI A;  2J0J A;  5KQ1 A;  1DBH A;  4F7U P;  3ULC A;  2LUL A;  4A6H A;  2Z0Q A;  1GG3 A;  1BTK A;  4K81 A;  2LG1 A;  2YRY A;  2OTX A;  1FGY A;  2DLW A;  4GN1 A;  1FB8 A;  2Y7B A;  3FM8 C;  4CYE A;  2NMB A;  1FOE A;  2R09 A;  4EKU A;  2D2Q A;  1UNP A;  4HB0 B;  4A6F B;  3GYP A;  1DDW A;  4WJ7 A;  2V76 A;  1FHX A;  2CAY A;  4GPT B;  1BWN A;  3T06 A;  1GC6 A;  1H4R A;  2YF0 A;  1WGQ A;  1XR0 B;  4KAX B;  5EFX A;  1BAK A;  2BCJ A;  2K00 A;  2RUK B;  2Z0O A;  2NZ8 B;  2AEH A;  2EMT A;  3ULB A;  3PVU A;  2RSG A;  3DXD A;  4HB4 B;  1EVH A;  4CHJ A;  1ZM0 A;  3ODO A;  5C5B B;  4Y94 A;  4D0N B;  4HAY B;  4MK0 A;  2Y8G A;  3SNH A;  2DN6 A;  3WA0 A;  4A6K A;  1TXD A;  2CY5 A;  4GZU A;  2RLO A;  4GXB A;  2ZPY A;  3KY9 A;  1V5P A;  4HAZ B;  2YS5 A;  1SHC A;  2EC1 A;  2J0K A;  3OAN A;  3ODX A;  2YT1 A;  2E2X A;  2D9Z A;  1U5F A;  1V5M A;  3HQC A;  3PVW A;  5DH9 B;  4EJN A;  2MDX A;  1P3R A;  2D9W A;  4B6H A;  3KRX A;  1OMW A;  1WVH A;  1WI1 A;  5GOW B;  1LB1 A;  2DHJ A;  2D9V A;  2RNR B;  2Q13 A;  1DDM A;  2MWN B;  3ZVR A;  1X1G A;  1ZC4 B;  2H7D A;  5J3Q A;  5DHA B;  1EGX A;  3QBV B;  4XWX A;  2OQB A;  5HE3 A;  4Z2N A;  5J3Y A;  1MIX A;  2L1C A;  2DKQ A;  1E5W A;  1MPH A;  2EJ8 A;  5JHG A;  2EMS A;  4K2O A;  3NSU A;  2W2X D;  4IOY X;  4BBK A;  2XQN M;  2DHK A;  4WVF B;  2ROV A;  1ZVR A;  2I1K A;  4HB2 B;  3WYF B;  1WGU A;  2D11 A;  1H10 A;  2J59 M;  3DXE A;  2ELA A;  1RJ2 A;  4A5K A;  4DBB A;  4ZRK A;  4YL8 A;  2HTH B;  3SYX A;  1I7A A;  2VRW B;  3GYO A;  4L6E A;  3M1I B;  1DYN A;  5KCV A;  1TJ6 A;  2YS1 A;  2IFS A;  1AQC A;  1I2H A;  5D3X A;  5C5B A;  5FI1 A;  2M14 A;  2LOX A;  2MKR A;  5C16 A;  1AWE A;  2GCL A;  4YON A;  4EMO A;  1U5G A;  2CY4 A;  2DYN A;  2RGN B;  4KHB B;  5L81 A;  1Y5O A;  2PZ1 A;  1J0W A;  4P7I A;  1UPR A;  1XCG A;  4F7G A;  3KZ1 A;  3MDB C;  4ZRJ A;  1RRP B;  1ISN A;  2G35 A;  1MK9 B;  3LJU X;  3BIN A;  2YT0 A;  2DA0 A;  1W1D A;  4C0A A;  1XOD A;  1KZ7 A;  3QIJ A;  1FGZ A;  1Q67 A;  1X1F A;  3QWM A;  1MKE A;  1UNR A;  5JHH A;  2GS0 A;  4HHV A;  2DHI A;  5CLL B;  2W2W A;  1M7R A;  3N7C A;  3X23 A;  3SV1 A;  1NTV A;  3KSY A;  3O96 A;  1UPQ A;  3TFM A;  3A98 B;  5JP4 A;  2D10 A;  4KVG B;  3A8Q A;  4K17 A;  4IAP A;  2RVB B;  4HDO A;  3HW2 B;  1MK7 B;  2Y8F A;  1OQN A;  3TCA A;  3D8F A;  1PLS A;  3TW1 A;  3A8P A;  1FHW A;  4Z2M B;  1XD4 A;  2VKI A;  1TQZ A;  1V5U A;  3VOQ A;  1SGH A;  3RCP A;  5HE2 A;  2IYB A;  2MFQ A;  4HAW B;  2R0D A;  3ML4 A;  1EF1 A;  1EAZ A;  4A6F A;  1UEF A;  1NTY A;  1XX0 A;  1Z87 A;  2ROZ B;  1DRO A;  2P0D A;  1N3H A;  2QKL A;  2N0Y A;  2DFK A;  3P6A A;  2QKM A;  1DDV A;  1K5G B;  1B55 A;  2DYQ A;  1IRS A;  1J19 A;  2CRF A;  2COF A;  3DXC A;  5KQ4 A;  4GMV A;  1U5D A;  4PQ0 A;  4HAV B;  1W1G A;  2YS3 A;  3TVV A;  3SO6 A;  2UVM A;  5J3T A;  3SUZ A;  3F5R A;  2I5C A;  4F7H A;  2COD A;  2COA A;  5D3V A;  2LOZ A;  4KHA A;  1U29 A;  1NU2 A;  3F0W A;  1K5D B;  5D3W A;  1P6S A;  4TYZ A;  4GMX B;  1QC6 A;  3AU5 A;  3FSS A;  2P8V A;  4HAX B;  5DIF B;  3CXB B;  3MPX A;  5LOP B;  1M7E A;  5JLJ B;  2KCJ A;  5HE0 A;  2KUP A;  5D3Y A;  3VIA A;  1NI2 A;  4HDQ A;  4HAT B;  2ELB A;  5DHF B;  2DX5 A;  1W1H A;  2H7E A;  1ZSQ A;  2YVC A;  3PVL A;  4WSF A;  2K2U A;  2KGX B;  2D9X A;  1UNQ A;  3PZD A;  1Y19 B;  3AU4 A;  2L2I A;  4CHM A;  4TKN A;  3U7D A;  1GC7 A;  3ZDT A;  3HK0 A;  1QQG A;  2P0H A;  2P0F A;  4KHO A;  1WJ1 A;  3PSC A;  3PG7 A;  5HE1 A;  2LKO A;  4NSW A;  1U2B A;  2J0M A;  2GCJ A;  1KI1 B;  2Z0P A;  3BJI A;  3U8Z A;  4K2P A;  2K2J A;  1MAI A;  4DXA B;  1FHO A;  5LON B;  2D4Q A;  2N23 A;  1MIZ B;  2FJL A;  1KZG A;  3AJ4 A;  3UZT A;  4DX8 A;  5D27 A;  3D8D A;  5DI9 B;  3TO1 A;  1X11 A;  2I1J A;  3V5W A;  2X18 A;  1PFJ A;  4HAU B;  4H8S A;  1WG7 A;  4DX9 0;  1U27 A;  1V89 A;  2AL6 A;  2UZR A;  3P7Z A;  4IFS A;  2DKP A;  1X86 A;  2DX1 A;  4NY0 A;  1V88 A;  2D9Y A;  2W2X C;  1V61 A;  2UZS A;  2COC A;  1ZC3 B;  5C79 A;  5CLQ B;  1FAO A;  1U5E A;  5C6R A;  2VSZ A;  3G9W A;  3FEH A;  1P5T A;  1X05 A;  2HE7 A;  2DTC A;  2M38 A;  3PEG A;  1WJM A;  2JP2 A;  1PMS A;  1BTN A;  3KRW A;  2I5F A;  4HB3 B;  3IVF A;  4MY6 A;  3PP2 A;  1LW3 A;  3ODW A;  3D8E A;  3CIK A;  1XKE A;  4MT7 A; 
#chains in the Genus database with same CATH topology
 4KHB A;  1OY2 A;  5FI0 A;  2YSZ A;  4PNK A;  2LYD A;  2GJY A;  2ADZ A;  4ZRI A;  2J0J A;  5KQ1 A;  1DBH A;  4F7U P;  3ULC A;  2LUL A;  4A6H A;  2Z0Q A;  1GG3 A;  1BTK A;  4K81 A;  2LG1 A;  2YRY A;  2OTX A;  1FGY A;  2DLW A;  4GN1 A;  1FB8 A;  2Y7B A;  3FM8 C;  4CYE A;  2NMB A;  2KR0 A;  1FOE A;  2R09 A;  4EKU A;  2D2Q A;  1UNP A;  4GOU A;  4HB0 B;  3GYP A;  4A6F B;  1DDW A;  4WJ7 A;  2V76 A;  1FHX A;  2CAY A;  4GPT B;  1BWN A;  3T06 A;  1GC6 A;  1H4R A;  1ZYI A;  2YF0 A;  1WGQ A;  1XR0 B;  4KAX B;  5EFX A;  1BAK A;  2BCJ A;  2K00 A;  2RUK B;  2Z0O A;  2NZ8 B;  2AEH A;  2EMT A;  3ULB A;  3PVU A;  2RSG A;  3DXD A;  4HB4 B;  1EVH A;  4CHJ A;  1ZM0 A;  3ODO A;  5C5B B;  4Y94 A;  4D0N B;  4HAY B;  4MK0 A;  2Y8G A;  3SNH A;  2DN6 A;  3WA0 A;  4A6K A;  1TXD A;  2CY5 A;  4GZU A;  2KUQ A;  2RLO A;  4GXB A;  2ZPY A;  3KY9 A;  1V5P A;  4HAZ B;  2YS5 A;  1SHC A;  2EC1 A;  2J0K A;  3OAN A;  3ODX A;  2YT1 A;  2E2X A;  2NBV A;  2D9Z A;  1U5F A;  1V5M A;  3HQC A;  3PVW A;  5DH9 B;  4EJN A;  2MDX A;  1P3R A;  2D9W A;  4B6H A;  3KRX A;  1OMW A;  1WVH A;  1WI1 A;  5GOW B;  4QJ5 B;  1LB1 A;  2DHJ A;  2D9V A;  2RNR B;  2Q13 A;  1DDM A;  2MWN B;  3ZVR A;  1X1G A;  1ZC4 B;  2H7D A;  5J3Q A;  5DHA B;  1EGX A;  3QBV B;  4XWX A;  2OQB A;  5HE3 A;  4Z2N A;  5J3Y A;  1MIX A;  2L1C A;  2DKQ A;  1E5W A;  1MPH A;  2EJ8 A;  5JHG A;  2EMS A;  4K2O A;  3NSU A;  2W2X D;  4IOY X;  4BBK A;  2XQN M;  2DHK A;  4WVF B;  2ROV A;  1ZVR A;  2I1K A;  4HB2 B;  3WYF B;  1WGU A;  2D11 A;  1H10 A;  2J59 M;  4QXA B;  3DXE A;  2ELA A;  1RJ2 A;  4A5K A;  4DBB A;  4ZRK A;  4YL8 A;  2HTH B;  3SYX A;  1I7A A;  2VRW B;  3GYO A;  4L6E A;  3M1I B;  1DYN A;  5KCV A;  1TJ6 A;  2YS1 A;  2IFS A;  1AQC A;  1I2H A;  5D3X A;  5C5B A;  5FI1 A;  2M14 A;  2LOX A;  2MKR A;  5C16 A;  1AWE A;  2GCL A;  4YON A;  4QJ4 B;  4EMO A;  5I2S A;  1U5G A;  2CY4 A;  2DYN A;  2RGN B;  4KHB B;  5L81 A;  1Y5O A;  2PZ1 A;  1J0W A;  4P7I A;  1UPR A;  1XCG A;  4F7G A;  2Z59 A;  3KZ1 A;  3MDB C;  4ZRJ A;  1RRP B;  2Z13 A;  4DIX A;  3U12 A;  1ISN A;  2G35 A;  4QJ3 B;  1MK9 B;  3LJU X;  3BIN A;  2YT0 A;  2DA0 A;  1W1D A;  4C0A A;  1XOD A;  1KZ7 A;  3QIJ A;  1FGZ A;  1MI1 A;  1Q67 A;  3HIE A;  4OSN A;  3FVC A;  1X1F A;  5IRS A;  3QWM A;  1MKE A;  1UNR A;  5JHH A;  2GS0 A;  2GUM A;  4HHV A;  2ZKM X;  2K8E A;  2DHI A;  5CLL B;  2W2W A;  1M7R A;  2RRF A;  3N7C A;  2Z14 A;  3X23 A;  3SV1 A;  4OT1 A;  1NTV A;  3KSY A;  3O96 A;  1UPQ A;  3TFM A;  3A98 B;  5JP4 A;  2D10 A;  4KVG B;  5I2M A;  3A8Q A;  4K17 A;  2YT2 A;  4IAP A;  2RVB B;  4HDO A;  3HW2 B;  1MK7 B;  2KIG A;  2Y8F A;  1OQN A;  4HSI A;  3TCA A;  3D8F A;  2R2Y A;  1PLS A;  3TW1 A;  3A8P A;  1FHW A;  4Z2M B;  1XD4 A;  2VKI A;  3NWD A;  2K49 A;  2FJU B;  3NW8 A;  4CSQ A;  1TQZ A;  1V5U A;  3VOQ A;  1SGH A;  3RCP A;  5HE2 A;  2IYB A;  2MFQ A;  4HAW B;  2R0D A;  3ML4 A;  1EF1 A;  1EAZ A;  4A6F A;  1UEF A;  1NTY A;  1XX0 A;  1Z87 A;  2ROZ B;  1DRO A;  2P0D A;  1N3H A;  2QKL A;  2N0Y A;  2DFK A;  3P6A A;  2QKM A;  1DDV A;  1K5G B;  1B55 A;  2DYQ A;  1IRS A;  1J19 A;  2CRF A;  2COF A;  3DXC A;  5KQ4 A;  3HSA A;  4GMV A;  1U5D A;  4PQ0 A;  4HAV B;  1W1G A;  2YS3 A;  3TVV A;  3SO6 A;  2UVM A;  5J3T A;  3SUZ A;  3F5R A;  2I5C A;  4F7H A;  2COD A;  2COA A;  5D3V A;  2Z4D A;  2LOZ A;  4KHA A;  1U29 A;  1NU2 A;  3F0W A;  1K5D B;  5D3W A;  1P6S A;  4TYZ A;  4GMX B;  1QC6 A;  3AU5 A;  3FSS A;  2P8V A;  4HAX B;  5DIF B;  3CXB B;  3MPX A;  5LOP B;  1M7E A;  5JLJ B;  4GNK B;  4L1R A;  2KCJ A;  5HE0 A;  2KUP A;  5D3Y A;  3VIA A;  1NI2 A;  4HDQ A;  4HAT B;  2ELB A;  5DHF B;  2DX5 A;  1W1H A;  2H7E A;  1ZSQ A;  2YVC A;  3PVL A;  4WSF A;  2K2U A;  2KGX B;  2D9X A;  1UNQ A;  3PZD A;  1Y19 B;  3AU4 A;  2L2I A;  4D6W A;  4CHM A;  4TKN A;  3U7D A;  1GC7 A;  3ZDT A;  3HK0 A;  1QQG A;  2P0H A;  2P0F A;  4KHO A;  1WJ1 A;  3PSC A;  3PG7 A;  5HE1 A;  2LKO A;  4NSW A;  1U2B A;  2J0M A;  2GCJ A;  1KI1 B;  2Z0P A;  3BJI A;  3U8Z A;  4K2P A;  2K2J A;  1MAI A;  4DXA B;  1FHO A;  2KIE A;  5LON B;  2D4Q A;  2N23 A;  1MIZ B;  2FJL A;  1KZG A;  3AJ4 A;  3UZT A;  4DX8 A;  5D27 A;  3D8D A;  5DI9 B;  3TO1 A;  1X11 A;  2I1J A;  3V5W A;  2X18 A;  1PFJ A;  4HAU B;  1T77 A;  4H8S A;  1WG7 A;  4DX9 0;  1U27 A;  1V89 A;  2AL6 A;  2UZR A;  3P7Z A;  4IFS A;  2DKP A;  1X86 A;  2DX1 A;  4NY0 A;  1V88 A;  2D9Y A;  2W2X C;  3B77 A;  1V61 A;  3OHM B;  2UZS A;  2COC A;  1ZC3 B;  5C79 A;  5CLQ B;  1FAO A;  1U5E A;  5C6R A;  3DCX A;  2VSZ A;  3G9W A;  3FEH A;  1P5T A;  1X05 A;  2HE7 A;  2DTC A;  2M38 A;  3NWA A;  3PEG A;  5LG4 B;  1WJM A;  2JP2 A;  1PMS A;  1BTN A;  3NWF A;  5M4Y B;  3KRW A;  2I5F A;  4HB3 B;  3IVF A;  4MY6 A;  3PP2 A;  1LW3 A;  3ODW A;  3D8E A;  3CIK A;  3A58 A;  1XKE A;  4MT7 A; 
#chains in the Genus database with same CATH homology
 1OY2 A;  5FI0 A;  2YSZ A;  4PNK A;  2LYD A;  2GJY A;  2ADZ A;  4ZRI A;  2J0J A;  5KQ1 A;  1DBH A;  4F7U P;  3ULC A;  2LUL A;  4A6H A;  2Z0Q A;  1GG3 A;  1BTK A;  4K81 A;  2LG1 A;  2YRY A;  2OTX A;  1FGY A;  2DLW A;  4GN1 A;  1FB8 A;  2Y7B A;  3FM8 C;  4CYE A;  2NMB A;  1FOE A;  2R09 A;  4EKU A;  2D2Q A;  1UNP A;  4HB0 B;  4A6F B;  3GYP A;  1DDW A;  4WJ7 A;  2V76 A;  1FHX A;  2CAY A;  4GPT B;  1BWN A;  3T06 A;  1GC6 A;  1H4R A;  2YF0 A;  1WGQ A;  1XR0 B;  4KAX B;  5EFX A;  1BAK A;  2BCJ A;  2K00 A;  2RUK B;  2Z0O A;  2NZ8 B;  2AEH A;  2EMT A;  3ULB A;  3PVU A;  2RSG A;  3DXD A;  4HB4 B;  1EVH A;  4CHJ A;  1ZM0 A;  3ODO A;  5C5B B;  4Y94 A;  4D0N B;  4HAY B;  4MK0 A;  2Y8G A;  3SNH A;  2DN6 A;  3WA0 A;  4A6K A;  1TXD A;  2CY5 A;  4GZU A;  2RLO A;  4GXB A;  2ZPY A;  3KY9 A;  1V5P A;  4HAZ B;  2YS5 A;  1SHC A;  2EC1 A;  2J0K A;  3OAN A;  3ODX A;  2YT1 A;  2E2X A;  2D9Z A;  1U5F A;  1V5M A;  3HQC A;  3PVW A;  5DH9 B;  4EJN A;  2MDX A;  1P3R A;  2D9W A;  4B6H A;  3KRX A;  1OMW A;  1WVH A;  1WI1 A;  5GOW B;  1LB1 A;  2DHJ A;  2D9V A;  2RNR B;  2Q13 A;  1DDM A;  2MWN B;  3ZVR A;  1X1G A;  1ZC4 B;  2H7D A;  5J3Q A;  5DHA B;  1EGX A;  3QBV B;  4XWX A;  2OQB A;  5HE3 A;  4Z2N A;  5J3Y A;  1MIX A;  2L1C A;  2DKQ A;  1E5W A;  1MPH A;  2EJ8 A;  5JHG A;  2EMS A;  4K2O A;  3NSU A;  2W2X D;  4IOY X;  4BBK A;  2XQN M;  2DHK A;  4WVF B;  2ROV A;  1ZVR A;  2I1K A;  4HB2 B;  3WYF B;  1WGU A;  2D11 A;  1H10 A;  2J59 M;  3DXE A;  2ELA A;  1RJ2 A;  4A5K A;  4DBB A;  4ZRK A;  4YL8 A;  2HTH B;  3SYX A;  1I7A A;  2VRW B;  3GYO A;  4L6E A;  3M1I B;  1DYN A;  5KCV A;  1TJ6 A;  2YS1 A;  2IFS A;  1AQC A;  1I2H A;  5D3X A;  5C5B A;  5FI1 A;  2M14 A;  2LOX A;  2MKR A;  5C16 A;  1AWE A;  2GCL A;  4YON A;  4EMO A;  1U5G A;  2CY4 A;  2DYN A;  2RGN B;  4KHB B;  5L81 A;  1Y5O A;  2PZ1 A;  1J0W A;  4P7I A;  1UPR A;  1XCG A;  4F7G A;  3KZ1 A;  3MDB C;  4ZRJ A;  1RRP B;  1ISN A;  2G35 A;  1MK9 B;  3LJU X;  3BIN A;  2YT0 A;  2DA0 A;  1W1D A;  4C0A A;  1XOD A;  1KZ7 A;  3QIJ A;  1FGZ A;  1Q67 A;  1X1F A;  3QWM A;  1MKE A;  1UNR A;  5JHH A;  2GS0 A;  4HHV A;  2DHI A;  5CLL B;  2W2W A;  1M7R A;  3N7C A;  3X23 A;  3SV1 A;  1NTV A;  3KSY A;  3O96 A;  1UPQ A;  3TFM A;  3A98 B;  5JP4 A;  2D10 A;  4KVG B;  3A8Q A;  4K17 A;  4IAP A;  2RVB B;  4HDO A;  3HW2 B;  1MK7 B;  2Y8F A;  1OQN A;  3TCA A;  3D8F A;  1PLS A;  3TW1 A;  3A8P A;  1FHW A;  4Z2M B;  1XD4 A;  2VKI A;  1TQZ A;  1V5U A;  3VOQ A;  1SGH A;  3RCP A;  5HE2 A;  2IYB A;  2MFQ A;  4HAW B;  2R0D A;  3ML4 A;  1EF1 A;  1EAZ A;  4A6F A;  1UEF A;  1NTY A;  1XX0 A;  1Z87 A;  2ROZ B;  1DRO A;  2P0D A;  1N3H A;  2QKL A;  2N0Y A;  2DFK A;  3P6A A;  2QKM A;  1DDV A;  1K5G B;  1B55 A;  2DYQ A;  1IRS A;  1J19 A;  2CRF A;  2COF A;  3DXC A;  5KQ4 A;  4GMV A;  1U5D A;  4PQ0 A;  4HAV B;  1W1G A;  2YS3 A;  3TVV A;  3SO6 A;  2UVM A;  5J3T A;  3SUZ A;  3F5R A;  2I5C A;  4F7H A;  2COD A;  2COA A;  5D3V A;  2LOZ A;  4KHA A;  1U29 A;  1NU2 A;  3F0W A;  1K5D B;  5D3W A;  1P6S A;  4TYZ A;  4GMX B;  1QC6 A;  3AU5 A;  3FSS A;  2P8V A;  4HAX B;  5DIF B;  3CXB B;  3MPX A;  5LOP B;  1M7E A;  5JLJ B;  2KCJ A;  5HE0 A;  2KUP A;  5D3Y A;  3VIA A;  1NI2 A;  4HDQ A;  4HAT B;  2ELB A;  5DHF B;  2DX5 A;  1W1H A;  2H7E A;  1ZSQ A;  2YVC A;  3PVL A;  4WSF A;  2K2U A;  2KGX B;  2D9X A;  1UNQ A;  3PZD A;  1Y19 B;  3AU4 A;  2L2I A;  4CHM A;  4TKN A;  3U7D A;  1GC7 A;  3ZDT A;  3HK0 A;  1QQG A;  2P0H A;  2P0F A;  4KHO A;  1WJ1 A;  3PSC A;  3PG7 A;  5HE1 A;  2LKO A;  4NSW A;  1U2B A;  2J0M A;  2GCJ A;  1KI1 B;  2Z0P A;  3BJI A;  3U8Z A;  4K2P A;  2K2J A;  1MAI A;  4DXA B;  1FHO A;  5LON B;  2D4Q A;  2N23 A;  1MIZ B;  2FJL A;  1KZG A;  3AJ4 A;  3UZT A;  4DX8 A;  5D27 A;  3D8D A;  5DI9 B;  3TO1 A;  1X11 A;  2I1J A;  3V5W A;  2X18 A;  1PFJ A;  4HAU B;  4H8S A;  1WG7 A;  4DX9 0;  1U27 A;  1V89 A;  2AL6 A;  2UZR A;  3P7Z A;  4IFS A;  2DKP A;  1X86 A;  2DX1 A;  4NY0 A;  1V88 A;  2D9Y A;  2W2X C;  1V61 A;  2UZS A;  2COC A;  1ZC3 B;  5C79 A;  5CLQ B;  1FAO A;  1U5E A;  5C6R A;  2VSZ A;  3G9W A;  3FEH A;  1P5T A;  1X05 A;  2HE7 A;  2DTC A;  2M38 A;  3PEG A;  1WJM A;  2JP2 A;  1PMS A;  1BTN A;  3KRW A;  2I5F A;  4HB3 B;  3IVF A;  4MY6 A;  3PP2 A;  1LW3 A;  3ODW A;  3D8E A;  3CIK A;  1XKE A;  4MT7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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