1IRSA

Irs-1 ptb domain complexed with a il-4 receptor phosphopeptide, nmr, minimized average structure
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
112
structure length
112
Chain Sequence
MGPAFKEVWQVILKPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSDEFRPR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain.
pubmed doi rcsb
molecule tags Complex (signal transduction/peptide)
source organism Homo sapiens
molecule keywords IRS-1
total genus 17
structure length 112
sequence length 112
ec nomenclature
pdb deposition date 1996-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02174 IRS PTB domain (IRS-1 type)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1irsA00
1Q67A 2H7EA 5JLJB 2GJYA 1KZGA 2IFSA 2NMBA 2RVBB 2LYDA 3M1IB 2DTCA 3TCAA 3U7DA 4IOYX 5GOWB 3TFMA 3F0WA 1Y5OA 5KQ4A 2MFQA 1GC7A 4HHVA 1X05A 3QWMA 1FGZA 3IVFA 2ROZB 2D10A 2CY5A 5JHGA 2P0DA 1P5TA 3A8QA 2YS3A 3G9WA 1U29A 1UEFA 5DIFB 2I1KA 2UZSA 4TKNA 4DX90 1BTNA 1DDWA 1WJMA 2D9WA 2I5CA 4A6FA 2I5FA 1J19A 4ZRJA 2RNRB 3BINA 2J0MA 4DX8A 1U5DA 5EFXA 4A6FB 4C0AA 2DKPA 3X23A 2COFA 2D9VA 1B55A 1W1GA 1LW3A 1WG7A 2L1CA 2RSGA 5J3TA 3BJIA 3ZDTA 1XR0B 2ADZA 3ZVRA 3SUZA 1WI1A 3N7CA 4KHOA 2COAA 4A6HA 1WGUA 1V89A 2J59M 5D3XA 1ZSQA 1NTVA 4F7UP 5JHHA 3P6AA 2DLWA 3MPXA 2LKOA 2L2IA 1ZC4B 3O96A 1LB1A 2N23A 4HAYB 4DBBA 3PVUA 4HATB 2D9XA 1M7EA 1BWNA 2D4QA 2Z0OA 2BCJA 5J3YA 1Z87A 1V88A 3TO1A 1WGQA 3SV1A 3WA0A 4MK0A 3KRWA 1K5GB 1BAKA 4HDQA 3TW1A 2N0YA 3AU4A 3QBVB 2UVMA 4KHBB 3LJUX 2HTHB 2R09A 1MIZB 1NI2A 4PNKA 3ODOA 1RJ2A 2QKMA 2KCJA 1BTKA 4MT7A 3CXBB 1N3HA 2D11A 1P3RA 3FEHA 2LOXA 1PMSA 3KRXA 3WYFB 3A98B 2EJ8A 5L81A 4Z2NA 1WJ1A 3PVLA 1FHOA 1OY2A 3VOQA 2P8VA 3HW2B 1UNPA 1U5GA 2W2XD 1MK9B 1W1DA 4K17A 2DYNA 3CIKA 3TVVA 2LG1A 5C79A 2K2UA 1OQNA 2K00A 1ZC3B 4BBKA 4WVFB 2KGXB 4GPTB 2RGNB 4NY0A 5KCVA 5JP4A 1V5UA 3PSCA 4DXAB 1TJ6A 3PZDA 3PEGA 2CY4A 2DX5A 2Q13A 1AQCA 4YONA 3HK0A 3AJ4A 3ML4A 1XKEA 3HQCA 3ODXA 1NTYA 4GXBA 2YF0A 1PFJA 2IYBA 2DHIA 2I1JA 3SNHA 3GYOA 5LOPB 2AEHA 4PQ0A 2OQBA 2M38A 2UZRA 1MIXA 2P0HA 2DA0A 3P7ZA 2CAYA 4EJNA 1FHXA 5HE1A 1V61A 3NSUA 1KZ7A 2LULA 2YS1A 2ELBA 1X1GA 2Z0QA 4YL8A 3U8ZA 5HE3A 1SGHA 2FJLA 2X18A 3SO6A 4ZRKA 2K2JA 1TQZA 1X1FA 4Z2MB 2EMTA 1AWEA 3OANA 3UZTA 2J0KA 1SHCA 3A8PA 2YRYA 3DXDA 2W2XC 1DBHA 4K2OA 2Y7BA 3V5WA 2CRFA 5FI0A 5D3VA 3D8DA 2GCLA 2XQNM 4F7HA 2YT0A 4ZRIA 1MK7B 1GC6A 3KY9A 1V5PA 1XODA 3GYPA 1I2HA 1ZVRA 4WJ7A 1X11A 2DKQA 1M7RA 2DHJA 1XX0A 1DDMA 3PG7A 1E5WA 5DH9B 2Y8GA 1U5FA 2M14A 1W1HA 2ELAA 3SYXA 2KUPA 4HDOA 1ZM0A 4K81A 1U5EA 2HE7A 2G35A 4EKUA 2E2XA 4GZUA 1X86A 1FAOA 4WSFA 1J0WA 1QC6A 1EVHA 1K5DB 1DROA 2W2WA 1DDVA 2YT1A 4CHJA 3RCPA 1P6SA 1UNRA 2DX1A 2VRWB 3KSYA 1FB8A 1FHWA 2DN6A 2D2QA 1XCGA 2LOZA 4HAUB 4HB4B 4GMXB 4CYEA 4HAZB 3D8FA 4A5KA 1FOEA 1H10A 1U2BA 1MKEA 1TXDA 3DXEA 2PZ1A 1UNQA 1PLSA 1OMWA 1WVHA 5C16A 5D3YA 2CODA 4KVGB 3MDBC 2MKRA 2GCJA 2VSZA 2VKIA 2D9ZA 5C6RA 1UPQA 2V76A 2YVCA 2D9YA 2RUKB 3PVWA 2Y8FA 3F5RA 3FM8C 4HB0B 4MY6A 3ULCA 4TYZA 4HAXB 1QQGA 4IAPA 1EF1A 2NZ8B 1XD4A 2GS0A 4HB2B 4HAWB 3PP2A 3VIAA 2ROVA 5LONB 5DI9B 1IRSA 4XWXA 1EAZA 1U27A 2J0JA 2QKLA 2RLOA 1UPRA 1DYNA 3QIJA 5HE0A 4NSWA 4K2PA 2MWNB 4CHMA 2YSZA 4L6EA 2DHKA 1ISNA 4B6HA 4A6KA 5C5BA 4GMVA 3ODWA 5DHFB 1EGXA 5KQ1A 2YS5A 3AU5A 5C5BB 2JP2A 2MDXA 4GN1A 2R0DA 4HAVB 5D27A 2COCA 3FSSA 2AL6A 2DFKA 1MAIA 3T06A 4P7IA 2DYQA 1FGYA 4KAXB 3ULBA 4H8SA 1I7AA 1KI1B 1RRPB 2OTXA 1V5MA 4F7GA 5J3QA 5CLQB 1H4RA 3DXCA 1NU2A 4Y94A 3KZ1A 2ZPYA 5DHAB 1MPHA 5HE2A 2EC1A 4HB3B 5CLLB 1Y19B 4KHAA 1GG3A 2H7DA 2EMSA 3D8EA 2P0FA 5FI1A 5D3WA 4IFSA 4D0NB 4EMOA 2Z0PA
chains in the Genus database with same CATH superfamily
1Q67A 2H7EA 3DCXA 5JLJB 2GJYA 1KZGA 2IFSA 2NMBA 2RVBB 1T77A 2LYDA 3M1IB 2DTCA 3TCAA 3U7DA 4IOYX 5GOWB 3TFMA 3F0WA 1Y5OA 5KQ4A 2MFQA 1ZYIA 1GC7A 4HHVA 1X05A 3QWMA 3OHMB 1FGZA 2KUQA 3IVFA 2ROZB 2D10A 2CY5A 5JHGA 2P0DA 1P5TA 3A8QA 2YS3A 3G9WA 1U29A 1UEFA 5DIFB 4GOUA 2I1KA 2UZSA 4TKNA 2Z13A 4DX90 1BTNA 1DDWA 2KR0A 1WJMA 2D9WA 2I5CA 4A6FA 2I5FA 1J19A 2KIEA 4ZRJA 2YT2A 2RNRB 3BINA 2J0MA 4DX8A 1U5DA 5EFXA 4A6FB 4C0AA 2DKPA 3X23A 2COFA 2D9VA 1B55A 1W1GA 1LW3A 1WG7A 2L1CA 2RSGA 5J3TA 3BJIA 3ZDTA 1XR0B 2ADZA 3ZVRA 3SUZA 1WI1A 3N7CA 4KHOA 2COAA 4A6HA 1WGUA 4OSNA 1V89A 2J59M 4L1RA 5D3XA 1ZSQA 1NTVA 4QJ3B 4F7UP 5JHHA 3P6AA 2DLWA 3MPXA 2K8EA 2LKOA 2L2IA 1ZC4B 3O96A 1LB1A 2N23A 4HAYB 4DBBA 3PVUA 2KIGA 4HATB 2D9XA 2Z59A 4CSQA 4OT1A 1M7EA 3NWFA 1BWNA 2D4QA 2Z0OA 2BCJA 5J3YA 1Z87A 1V88A 3TO1A 1WGQA 3SV1A 3WA0A 4MK0A 3KRWA 1K5GB 1BAKA 4HDQA 3TW1A 2N0YA 3AU4A 3QBVB 2UVMA 4KHBB 3LJUX 2HTHB 2R09A 1MIZB 1NI2A 4PNKA 3FVCA 3ODOA 1RJ2A 2QKMA 2KCJA 1BTKA 4MT7A 3CXBB 1N3HA 2D11A 1P3RA 3FEHA 2LOXA 1PMSA 3KRXA 3WYFB 3A98B 2EJ8A 5L81A 4Z2NA 1WJ1A 3PVLA 1FHOA 1OY2A 3VOQA 4QXAB 2P8VA 3HW2B 1UNPA 1U5GA 2W2XD 1MK9B 1W1DA 4K17A 2DYNA 3CIKA 3TVVA 2LG1A 5C79A 3HSAA 2K2UA 1OQNA 2K00A 1ZC3B 4BBKA 4WVFB 2KGXB 4GPTB 2RGNB 4NY0A 5KCVA 5JP4A 1V5UA 3PSCA 4DXAB 1TJ6A 3PZDA 3PEGA 2CY4A 2DX5A 2Q13A 1AQCA 4YONA 3HK0A 3AJ4A 3ML4A 1XKEA 3HQCA 3ODXA 1NTYA 4GXBA 2YF0A 1PFJA 2IYBA 2DHIA 2I1JA 3SNHA 3GYOA 5LOPB 5LG4B 2AEHA 4PQ0A 2RRFA 2OQBA 2M38A 2UZRA 3U12A 1MIXA 2P0HA 2DA0A 3P7ZA 2CAYA 4HSIA 4EJNA 4QJ4B 1FHXA 5HE1A 2FJUB 2GUMA 1V61A 3NSUA 1KZ7A 2LULA 2YS1A 2ELBA 1X1GA 2Z0QA 4YL8A 3U8ZA 5HE3A 1SGHA 2FJLA 2X18A 3SO6A 4ZRKA 2K2JA 1TQZA 1X1FA 4Z2MB 2EMTA 1AWEA 3OANA 3UZTA 2R2YA 2J0KA 4DIXA 1SHCA 2K49A 3A8PA 2YRYA 3DXDA 2W2XC 1DBHA 4K2OA 2Y7BA 3V5WA 2CRFA 5FI0A 5D3VA 3D8DA 2GCLA 2XQNM 4KHBA 3NWDA 4F7HA 2YT0A 4ZRIA 1MK7B 1GC6A 1MI1A 3KY9A 1V5PA 1XODA 3GYPA 1I2HA 1ZVRA 4WJ7A 1X11A 2DKQA 1M7RA 2DHJA 1XX0A 1DDMA 3PG7A 1E5WA 5DH9B 2ZKMX 2Y8GA 3NW8A 1U5FA 4D6WA 2M14A 1W1HA 2ELAA 3SYXA 3B77A 2KUPA 4HDOA 1ZM0A 4K81A 1U5EA 2HE7A 2G35A 4EKUA 2E2XA 4GZUA 1X86A 1FAOA 4WSFA 1J0WA 1QC6A 1EVHA 1K5DB 1DROA 2W2WA 1DDVA 2YT1A 5IRSA 4CHJA 3RCPA 1P6SA 1UNRA 2DX1A 2VRWB 3KSYA 1FB8A 1FHWA 2DN6A 2D2QA 1XCGA 2LOZA 4HAUB 4HB4B 4GMXB 4CYEA 4HAZB 3D8FA 4A5KA 1FOEA 1H10A 1U2BA 1MKEA 1TXDA 3DXEA 2PZ1A 1UNQA 1PLSA 1OMWA 1WVHA 5C16A 5D3YA 2CODA 4KVGB 4QJ5B 3A58A 3MDBC 2MKRA 2GCJA 2VSZA 2VKIA 2D9ZA 5C6RA 1UPQA 2V76A 2YVCA 2D9YA 2RUKB 3PVWA 2Y8FA 3F5RA 5I2MA 3FM8C 4HB0B 4MY6A 2Z4DA 3ULCA 4TYZA 4HAXB 1QQGA 4IAPA 1EF1A 2NZ8B 1XD4A 2GS0A 4HB2B 4HAWB 3PP2A 3VIAA 2ROVA 5LONB 5DI9B 1IRSA 4XWXA 1EAZA 1U27A 2J0JA 2QKLA 2RLOA 1UPRA 1DYNA 3QIJA 5HE0A 4NSWA 4K2PA 2MWNB 4CHMA 2YSZA 4L6EA 2DHKA 1ISNA 4B6HA 4A6KA 5C5BA 3NWAA 4GMVA 3HIEA 3ODWA 5DHFB 1EGXA 5KQ1A 2YS5A 3AU5A 5C5BB 2JP2A 2MDXA 4GN1A 2NBVA 2R0DA 4HAVB 5D27A 2COCA 3FSSA 2AL6A 2DFKA 1MAIA 3T06A 5M4YB 4P7IA 2DYQA 1FGYA 4KAXB 3ULBA 4H8SA 1I7AA 1KI1B 1RRPB 2OTXA 1V5MA 4F7GA 5J3QA 5CLQB 4GNKB 1H4RA 3DXCA 1NU2A 4Y94A 3KZ1A 2ZPYA 2Z14A 5DHAB 1MPHA 5HE2A 2EC1A 4HB3B 5CLLB 1Y19B 5I2SA 4KHAA 1GG3A 2H7DA 2EMSA 3D8EA 2P0FA 5FI1A 5D3WA 4IFSA 4D0NB 4EMOA 2Z0PA
chains in the Genus database with same CATH topology
1Q67A 2H7EA 5JLJB 2GJYA 1KZGA 2IFSA 2NMBA 2RVBB 2LYDA 3M1IB 2DTCA 3TCAA 3U7DA 4IOYX 5GOWB 3TFMA 3F0WA 1Y5OA 5KQ4A 2MFQA 1GC7A 4HHVA 1X05A 3QWMA 1FGZA 3IVFA 2ROZB 2D10A 2CY5A 5JHGA 2P0DA 1P5TA 3A8QA 2YS3A 3G9WA 1U29A 1UEFA 5DIFB 2I1KA 2UZSA 4TKNA 4DX90 1BTNA 1DDWA 1WJMA 2D9WA 2I5CA 4A6FA 2I5FA 1J19A 4ZRJA 2RNRB 3BINA 2J0MA 4DX8A 1U5DA 5EFXA 4A6FB 4C0AA 2DKPA 3X23A 2COFA 2D9VA 1B55A 1W1GA 1LW3A 1WG7A 2L1CA 2RSGA 5J3TA 3BJIA 3ZDTA 1XR0B 2ADZA 3ZVRA 3SUZA 1WI1A 3N7CA 4KHOA 2COAA 4A6HA 1WGUA 1V89A 2J59M 5D3XA 1ZSQA 1NTVA 4F7UP 5JHHA 3P6AA 2DLWA 3MPXA 2LKOA 2L2IA 1ZC4B 3O96A 1LB1A 2N23A 4HAYB 4DBBA 3PVUA 4HATB 2D9XA 1M7EA 1BWNA 2D4QA 2Z0OA 2BCJA 5J3YA 1Z87A 1V88A 3TO1A 1WGQA 3SV1A 3WA0A 4MK0A 3KRWA 1K5GB 1BAKA 4HDQA 3TW1A 2N0YA 3AU4A 3QBVB 2UVMA 4KHBB 3LJUX 2HTHB 2R09A 1MIZB 1NI2A 4PNKA 3ODOA 1RJ2A 2QKMA 2KCJA 1BTKA 4MT7A 3CXBB 1N3HA 2D11A 1P3RA 3FEHA 2LOXA 1PMSA 3KRXA 3WYFB 3A98B 2EJ8A 5L81A 4Z2NA 1WJ1A 3PVLA 1FHOA 1OY2A 3VOQA 2P8VA 3HW2B 1UNPA 1U5GA 2W2XD 1MK9B 1W1DA 4K17A 2DYNA 3CIKA 3TVVA 2LG1A 5C79A 2K2UA 1OQNA 2K00A 1ZC3B 4BBKA 4WVFB 2KGXB 4GPTB 2RGNB 4NY0A 5KCVA 5JP4A 1V5UA 3PSCA 4DXAB 1TJ6A 3PZDA 3PEGA 2CY4A 2DX5A 2Q13A 1AQCA 4YONA 3HK0A 3AJ4A 3ML4A 1XKEA 3HQCA 3ODXA 1NTYA 4GXBA 2YF0A 1PFJA 2IYBA 2DHIA 2I1JA 3SNHA 3GYOA 5LOPB 2AEHA 4PQ0A 2OQBA 2M38A 2UZRA 1MIXA 2P0HA 2DA0A 3P7ZA 2CAYA 4EJNA 1FHXA 5HE1A 1V61A 3NSUA 1KZ7A 2LULA 2YS1A 2ELBA 1X1GA 2Z0QA 4YL8A 3U8ZA 5HE3A 1SGHA 2FJLA 2X18A 3SO6A 4ZRKA 2K2JA 1TQZA 1X1FA 4Z2MB 2EMTA 1AWEA 3OANA 3UZTA 2J0KA 1SHCA 3A8PA 2YRYA 3DXDA 2W2XC 1DBHA 4K2OA 2Y7BA 3V5WA 2CRFA 5FI0A 5D3VA 3D8DA 2GCLA 2XQNM 4F7HA 2YT0A 4ZRIA 1MK7B 1GC6A 3KY9A 1V5PA 1XODA 3GYPA 1I2HA 1ZVRA 4WJ7A 1X11A 2DKQA 1M7RA 2DHJA 1XX0A 1DDMA 3PG7A 1E5WA 5DH9B 2Y8GA 1U5FA 2M14A 1W1HA 2ELAA 3SYXA 2KUPA 4HDOA 1ZM0A 4K81A 1U5EA 2HE7A 2G35A 4EKUA 2E2XA 4GZUA 1X86A 1FAOA 4WSFA 1J0WA 1QC6A 1EVHA 1K5DB 1DROA 2W2WA 1DDVA 2YT1A 4CHJA 3RCPA 1P6SA 1UNRA 2DX1A 2VRWB 3KSYA 1FB8A 1FHWA 2DN6A 2D2QA 1XCGA 2LOZA 4HAUB 4HB4B 4GMXB 4CYEA 4HAZB 3D8FA 4A5KA 1FOEA 1H10A 1U2BA 1MKEA 1TXDA 3DXEA 2PZ1A 1UNQA 1PLSA 1OMWA 1WVHA 5C16A 5D3YA 2CODA 4KVGB 3MDBC 2MKRA 2GCJA 2VSZA 2VKIA 2D9ZA 5C6RA 1UPQA 2V76A 2YVCA 2D9YA 2RUKB 3PVWA 2Y8FA 3F5RA 3FM8C 4HB0B 4MY6A 3ULCA 4TYZA 4HAXB 1QQGA 4IAPA 1EF1A 2NZ8B 1XD4A 2GS0A 4HB2B 4HAWB 3PP2A 3VIAA 2ROVA 5LONB 5DI9B 1IRSA 4XWXA 1EAZA 1U27A 2J0JA 2QKLA 2RLOA 1UPRA 1DYNA 3QIJA 5HE0A 4NSWA 4K2PA 2MWNB 4CHMA 2YSZA 4L6EA 2DHKA 1ISNA 4B6HA 4A6KA 5C5BA 4GMVA 3ODWA 5DHFB 1EGXA 5KQ1A 2YS5A 3AU5A 5C5BB 2JP2A 2MDXA 4GN1A 2R0DA 4HAVB 5D27A 2COCA 3FSSA 2AL6A 2DFKA 1MAIA 3T06A 4P7IA 2DYQA 1FGYA 4KAXB 3ULBA 4H8SA 1I7AA 1KI1B 1RRPB 2OTXA 1V5MA 4F7GA 5J3QA 5CLQB 1H4RA 3DXCA 1NU2A 4Y94A 3KZ1A 2ZPYA 5DHAB 1MPHA 5HE2A 2EC1A 4HB3B 5CLLB 1Y19B 4KHAA 1GG3A 2H7DA 2EMSA 3D8EA 2P0FA 5FI1A 5D3WA 4IFSA 4D0NB 4EMOA 2Z0PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Q67 A;  2H7E A;  5JLJ B;  2GJY A;  1KZG A;  2IFS A;  2NMB A;  2RVB B;  2LYD A;  3M1I B;  2DTC A;  3TCA A;  3U7D A;  4IOY X;  5GOW B;  3TFM A;  3F0W A;  1Y5O A;  5KQ4 A;  2MFQ A;  1GC7 A;  4HHV A;  1X05 A;  3QWM A;  1FGZ A;  3IVF A;  2ROZ B;  2D10 A;  2CY5 A;  5JHG A;  2P0D A;  1P5T A;  3A8Q A;  2YS3 A;  3G9W A;  1U29 A;  1UEF A;  5DIF B;  2I1K A;  2UZS A;  4TKN A;  4DX9 0;  1BTN A;  1DDW A;  1WJM A;  2D9W A;  2I5C A;  4A6F A;  2I5F A;  1J19 A;  4ZRJ A;  2RNR B;  3BIN A;  2J0M A;  4DX8 A;  1U5D A;  5EFX A;  4A6F B;  4C0A A;  2DKP A;  3X23 A;  2COF A;  2D9V A;  1B55 A;  1W1G A;  1LW3 A;  1WG7 A;  2L1C A;  2RSG A;  5J3T A;  3BJI A;  3ZDT A;  1XR0 B;  2ADZ A;  3ZVR A;  3SUZ A;  1WI1 A;  3N7C A;  4KHO A;  2COA A;  4A6H A;  1WGU A;  1V89 A;  2J59 M;  5D3X A;  1ZSQ A;  1NTV A;  4F7U P;  5JHH A;  3P6A A;  2DLW A;  3MPX A;  2LKO A;  2L2I A;  1ZC4 B;  3O96 A;  1LB1 A;  2N23 A;  4HAY B;  4DBB A;  3PVU A;  4HAT B;  2D9X A;  1M7E A;  1BWN A;  2D4Q A;  2Z0O A;  2BCJ A;  5J3Y A;  1Z87 A;  1V88 A;  3TO1 A;  1WGQ A;  3SV1 A;  3WA0 A;  4MK0 A;  3KRW A;  1K5G B;  1BAK A;  4HDQ A;  3TW1 A;  2N0Y A;  3AU4 A;  3QBV B;  2UVM A;  4KHB B;  3LJU X;  2HTH B;  2R09 A;  1MIZ B;  1NI2 A;  4PNK A;  3ODO A;  1RJ2 A;  2QKM A;  2KCJ A;  1BTK A;  4MT7 A;  3CXB B;  1N3H A;  2D11 A;  1P3R A;  3FEH A;  2LOX A;  1PMS A;  3KRX A;  3WYF B;  3A98 B;  2EJ8 A;  5L81 A;  4Z2N A;  1WJ1 A;  3PVL A;  1FHO A;  1OY2 A;  3VOQ A;  2P8V A;  3HW2 B;  1UNP A;  1U5G A;  2W2X D;  1MK9 B;  1W1D A;  4K17 A;  2DYN A;  3CIK A;  3TVV A;  2LG1 A;  5C79 A;  2K2U A;  1OQN A;  2K00 A;  1ZC3 B;  4BBK A;  4WVF B;  2KGX B;  4GPT B;  2RGN B;  4NY0 A;  5KCV A;  5JP4 A;  1V5U A;  3PSC A;  4DXA B;  1TJ6 A;  3PZD A;  3PEG A;  2CY4 A;  2DX5 A;  2Q13 A;  1AQC A;  4YON A;  3HK0 A;  3AJ4 A;  3ML4 A;  1XKE A;  3HQC A;  3ODX A;  1NTY A;  4GXB A;  2YF0 A;  1PFJ A;  2IYB A;  2DHI A;  2I1J A;  3SNH A;  3GYO A;  5LOP B;  2AEH A;  4PQ0 A;  2OQB A;  2M38 A;  2UZR A;  1MIX A;  2P0H A;  2DA0 A;  3P7Z A;  2CAY A;  4EJN A;  1FHX A;  5HE1 A;  1V61 A;  3NSU A;  1KZ7 A;  2LUL A;  2YS1 A;  2ELB A;  1X1G A;  2Z0Q A;  4YL8 A;  3U8Z A;  5HE3 A;  1SGH A;  2FJL A;  2X18 A;  3SO6 A;  4ZRK A;  2K2J A;  1TQZ A;  1X1F A;  4Z2M B;  2EMT A;  1AWE A;  3OAN A;  3UZT A;  2J0K A;  1SHC A;  3A8P A;  2YRY A;  3DXD A;  2W2X C;  1DBH A;  4K2O A;  2Y7B A;  3V5W A;  2CRF A;  5FI0 A;  5D3V A;  3D8D A;  2GCL A;  2XQN M;  4F7H A;  2YT0 A;  4ZRI A;  1MK7 B;  1GC6 A;  3KY9 A;  1V5P A;  1XOD A;  3GYP A;  1I2H A;  1ZVR A;  4WJ7 A;  1X11 A;  2DKQ A;  1M7R A;  2DHJ A;  1XX0 A;  1DDM A;  3PG7 A;  1E5W A;  5DH9 B;  2Y8G A;  1U5F A;  2M14 A;  1W1H A;  2ELA A;  3SYX A;  2KUP A;  4HDO A;  1ZM0 A;  4K81 A;  1U5E A;  2HE7 A;  2G35 A;  4EKU A;  2E2X A;  4GZU A;  1X86 A;  1FAO A;  4WSF A;  1J0W A;  1QC6 A;  1EVH A;  1K5D B;  1DRO A;  2W2W A;  1DDV A;  2YT1 A;  4CHJ A;  3RCP A;  1P6S A;  1UNR A;  2DX1 A;  2VRW B;  3KSY A;  1FB8 A;  1FHW A;  2DN6 A;  2D2Q A;  1XCG A;  2LOZ A;  4HAU B;  4HB4 B;  4GMX B;  4CYE A;  4HAZ B;  3D8F A;  4A5K A;  1FOE A;  1H10 A;  1U2B A;  1MKE A;  1TXD A;  3DXE A;  2PZ1 A;  1UNQ A;  1PLS A;  1OMW A;  1WVH A;  5C16 A;  5D3Y A;  2COD A;  4KVG B;  3MDB C;  2MKR A;  2GCJ A;  2VSZ A;  2VKI A;  2D9Z A;  5C6R A;  1UPQ A;  2V76 A;  2YVC A;  2D9Y A;  2RUK B;  3PVW A;  2Y8F A;  3F5R A;  3FM8 C;  4HB0 B;  4MY6 A;  3ULC A;  4TYZ A;  4HAX B;  1QQG A;  4IAP A;  1EF1 A;  2NZ8 B;  1XD4 A;  2GS0 A;  4HB2 B;  4HAW B;  3PP2 A;  3VIA A;  2ROV A;  5LON B;  5DI9 B;  1IRS A;  4XWX A;  1EAZ A;  1U27 A;  2J0J A;  2QKL A;  2RLO A;  1UPR A;  1DYN A;  3QIJ A;  5HE0 A;  4NSW A;  4K2P A;  2MWN B;  4CHM A;  2YSZ A;  4L6E A;  2DHK A;  1ISN A;  4B6H A;  4A6K A;  5C5B A;  4GMV A;  3ODW A;  5DHF B;  1EGX A;  5KQ1 A;  2YS5 A;  3AU5 A;  5C5B B;  2JP2 A;  2MDX A;  4GN1 A;  2R0D A;  4HAV B;  5D27 A;  2COC A;  3FSS A;  2AL6 A;  2DFK A;  1MAI A;  3T06 A;  4P7I A;  2DYQ A;  1FGY A;  4KAX B;  3ULB A;  4H8S A;  1I7A A;  1KI1 B;  1RRP B;  2OTX A;  1V5M A;  4F7G A;  5J3Q A;  5CLQ B;  1H4R A;  3DXC A;  1NU2 A;  4Y94 A;  3KZ1 A;  2ZPY A;  5DHA B;  1MPH A;  5HE2 A;  2EC1 A;  4HB3 B;  5CLL B;  1Y19 B;  4KHA A;  1GG3 A;  2H7D A;  2EMS A;  3D8E A;  2P0F A;  5FI1 A;  5D3W A;  4IFS A;  4D0N B;  4EMO A;  2Z0P A; 
#chains in the Genus database with same CATH topology
 1Q67 A;  2H7E A;  3DCX A;  5JLJ B;  2GJY A;  1KZG A;  2IFS A;  2NMB A;  2RVB B;  1T77 A;  2LYD A;  3M1I B;  2DTC A;  3TCA A;  3U7D A;  4IOY X;  5GOW B;  3TFM A;  3F0W A;  1Y5O A;  5KQ4 A;  2MFQ A;  1ZYI A;  1GC7 A;  4HHV A;  1X05 A;  3QWM A;  3OHM B;  1FGZ A;  2KUQ A;  3IVF A;  2ROZ B;  2D10 A;  2CY5 A;  5JHG A;  2P0D A;  1P5T A;  3A8Q A;  2YS3 A;  3G9W A;  1U29 A;  1UEF A;  5DIF B;  4GOU A;  2I1K A;  2UZS A;  4TKN A;  2Z13 A;  4DX9 0;  1BTN A;  1DDW A;  2KR0 A;  1WJM A;  2D9W A;  2I5C A;  4A6F A;  2I5F A;  1J19 A;  2KIE A;  4ZRJ A;  2YT2 A;  2RNR B;  3BIN A;  2J0M A;  4DX8 A;  1U5D A;  5EFX A;  4A6F B;  4C0A A;  2DKP A;  3X23 A;  2COF A;  2D9V A;  1B55 A;  1W1G A;  1LW3 A;  1WG7 A;  2L1C A;  2RSG A;  5J3T A;  3BJI A;  3ZDT A;  1XR0 B;  2ADZ A;  3ZVR A;  3SUZ A;  1WI1 A;  3N7C A;  4KHO A;  2COA A;  4A6H A;  1WGU A;  4OSN A;  1V89 A;  2J59 M;  4L1R A;  5D3X A;  1ZSQ A;  1NTV A;  4QJ3 B;  4F7U P;  5JHH A;  3P6A A;  2DLW A;  3MPX A;  2K8E A;  2LKO A;  2L2I A;  1ZC4 B;  3O96 A;  1LB1 A;  2N23 A;  4HAY B;  4DBB A;  3PVU A;  2KIG A;  4HAT B;  2D9X A;  2Z59 A;  4CSQ A;  4OT1 A;  1M7E A;  3NWF A;  1BWN A;  2D4Q A;  2Z0O A;  2BCJ A;  5J3Y A;  1Z87 A;  1V88 A;  3TO1 A;  1WGQ A;  3SV1 A;  3WA0 A;  4MK0 A;  3KRW A;  1K5G B;  1BAK A;  4HDQ A;  3TW1 A;  2N0Y A;  3AU4 A;  3QBV B;  2UVM A;  4KHB B;  3LJU X;  2HTH B;  2R09 A;  1MIZ B;  1NI2 A;  4PNK A;  3FVC A;  3ODO A;  1RJ2 A;  2QKM A;  2KCJ A;  1BTK A;  4MT7 A;  3CXB B;  1N3H A;  2D11 A;  1P3R A;  3FEH A;  2LOX A;  1PMS A;  3KRX A;  3WYF B;  3A98 B;  2EJ8 A;  5L81 A;  4Z2N A;  1WJ1 A;  3PVL A;  1FHO A;  1OY2 A;  3VOQ A;  4QXA B;  2P8V A;  3HW2 B;  1UNP A;  1U5G A;  2W2X D;  1MK9 B;  1W1D A;  4K17 A;  2DYN A;  3CIK A;  3TVV A;  2LG1 A;  5C79 A;  3HSA A;  2K2U A;  1OQN A;  2K00 A;  1ZC3 B;  4BBK A;  4WVF B;  2KGX B;  4GPT B;  2RGN B;  4NY0 A;  5KCV A;  5JP4 A;  1V5U A;  3PSC A;  4DXA B;  1TJ6 A;  3PZD A;  3PEG A;  2CY4 A;  2DX5 A;  2Q13 A;  1AQC A;  4YON A;  3HK0 A;  3AJ4 A;  3ML4 A;  1XKE A;  3HQC A;  3ODX A;  1NTY A;  4GXB A;  2YF0 A;  1PFJ A;  2IYB A;  2DHI A;  2I1J A;  3SNH A;  3GYO A;  5LOP B;  5LG4 B;  2AEH A;  4PQ0 A;  2RRF A;  2OQB A;  2M38 A;  2UZR A;  3U12 A;  1MIX A;  2P0H A;  2DA0 A;  3P7Z A;  2CAY A;  4HSI A;  4EJN A;  4QJ4 B;  1FHX A;  5HE1 A;  2FJU B;  2GUM A;  1V61 A;  3NSU A;  1KZ7 A;  2LUL A;  2YS1 A;  2ELB A;  1X1G A;  2Z0Q A;  4YL8 A;  3U8Z A;  5HE3 A;  1SGH A;  2FJL A;  2X18 A;  3SO6 A;  4ZRK A;  2K2J A;  1TQZ A;  1X1F A;  4Z2M B;  2EMT A;  1AWE A;  3OAN A;  3UZT A;  2R2Y A;  2J0K A;  4DIX A;  1SHC A;  2K49 A;  3A8P A;  2YRY A;  3DXD A;  2W2X C;  1DBH A;  4K2O A;  2Y7B A;  3V5W A;  2CRF A;  5FI0 A;  5D3V A;  3D8D A;  2GCL A;  2XQN M;  4KHB A;  3NWD A;  4F7H A;  2YT0 A;  4ZRI A;  1MK7 B;  1GC6 A;  1MI1 A;  3KY9 A;  1V5P A;  1XOD A;  3GYP A;  1I2H A;  1ZVR A;  4WJ7 A;  1X11 A;  2DKQ A;  1M7R A;  2DHJ A;  1XX0 A;  1DDM A;  3PG7 A;  1E5W A;  5DH9 B;  2ZKM X;  2Y8G A;  3NW8 A;  1U5F A;  4D6W A;  2M14 A;  1W1H A;  2ELA A;  3SYX A;  3B77 A;  2KUP A;  4HDO A;  1ZM0 A;  4K81 A;  1U5E A;  2HE7 A;  2G35 A;  4EKU A;  2E2X A;  4GZU A;  1X86 A;  1FAO A;  4WSF A;  1J0W A;  1QC6 A;  1EVH A;  1K5D B;  1DRO A;  2W2W A;  1DDV A;  2YT1 A;  5IRS A;  4CHJ A;  3RCP A;  1P6S A;  1UNR A;  2DX1 A;  2VRW B;  3KSY A;  1FB8 A;  1FHW A;  2DN6 A;  2D2Q A;  1XCG A;  2LOZ A;  4HAU B;  4HB4 B;  4GMX B;  4CYE A;  4HAZ B;  3D8F A;  4A5K A;  1FOE A;  1H10 A;  1U2B A;  1MKE A;  1TXD A;  3DXE A;  2PZ1 A;  1UNQ A;  1PLS A;  1OMW A;  1WVH A;  5C16 A;  5D3Y A;  2COD A;  4KVG B;  4QJ5 B;  3A58 A;  3MDB C;  2MKR A;  2GCJ A;  2VSZ A;  2VKI A;  2D9Z A;  5C6R A;  1UPQ A;  2V76 A;  2YVC A;  2D9Y A;  2RUK B;  3PVW A;  2Y8F A;  3F5R A;  5I2M A;  3FM8 C;  4HB0 B;  4MY6 A;  2Z4D A;  3ULC A;  4TYZ A;  4HAX B;  1QQG A;  4IAP A;  1EF1 A;  2NZ8 B;  1XD4 A;  2GS0 A;  4HB2 B;  4HAW B;  3PP2 A;  3VIA A;  2ROV A;  5LON B;  5DI9 B;  1IRS A;  4XWX A;  1EAZ A;  1U27 A;  2J0J A;  2QKL A;  2RLO A;  1UPR A;  1DYN A;  3QIJ A;  5HE0 A;  4NSW A;  4K2P A;  2MWN B;  4CHM A;  2YSZ A;  4L6E A;  2DHK A;  1ISN A;  4B6H A;  4A6K A;  5C5B A;  3NWA A;  4GMV A;  3HIE A;  3ODW A;  5DHF B;  1EGX A;  5KQ1 A;  2YS5 A;  3AU5 A;  5C5B B;  2JP2 A;  2MDX A;  4GN1 A;  2NBV A;  2R0D A;  4HAV B;  5D27 A;  2COC A;  3FSS A;  2AL6 A;  2DFK A;  1MAI A;  3T06 A;  5M4Y B;  4P7I A;  2DYQ A;  1FGY A;  4KAX B;  3ULB A;  4H8S A;  1I7A A;  1KI1 B;  1RRP B;  2OTX A;  1V5M A;  4F7G A;  5J3Q A;  5CLQ B;  4GNK B;  1H4R A;  3DXC A;  1NU2 A;  4Y94 A;  3KZ1 A;  2ZPY A;  2Z14 A;  5DHA B;  1MPH A;  5HE2 A;  2EC1 A;  4HB3 B;  5CLL B;  1Y19 B;  5I2S A;  4KHA A;  1GG3 A;  2H7D A;  2EMS A;  3D8E A;  2P0F A;  5FI1 A;  5D3W A;  4IFS A;  4D0N B;  4EMO A;  2Z0P A; 
#chains in the Genus database with same CATH homology
 1Q67 A;  2H7E A;  5JLJ B;  2GJY A;  1KZG A;  2IFS A;  2NMB A;  2RVB B;  2LYD A;  3M1I B;  2DTC A;  3TCA A;  3U7D A;  4IOY X;  5GOW B;  3TFM A;  3F0W A;  1Y5O A;  5KQ4 A;  2MFQ A;  1GC7 A;  4HHV A;  1X05 A;  3QWM A;  1FGZ A;  3IVF A;  2ROZ B;  2D10 A;  2CY5 A;  5JHG A;  2P0D A;  1P5T A;  3A8Q A;  2YS3 A;  3G9W A;  1U29 A;  1UEF A;  5DIF B;  2I1K A;  2UZS A;  4TKN A;  4DX9 0;  1BTN A;  1DDW A;  1WJM A;  2D9W A;  2I5C A;  4A6F A;  2I5F A;  1J19 A;  4ZRJ A;  2RNR B;  3BIN A;  2J0M A;  4DX8 A;  1U5D A;  5EFX A;  4A6F B;  4C0A A;  2DKP A;  3X23 A;  2COF A;  2D9V A;  1B55 A;  1W1G A;  1LW3 A;  1WG7 A;  2L1C A;  2RSG A;  5J3T A;  3BJI A;  3ZDT A;  1XR0 B;  2ADZ A;  3ZVR A;  3SUZ A;  1WI1 A;  3N7C A;  4KHO A;  2COA A;  4A6H A;  1WGU A;  1V89 A;  2J59 M;  5D3X A;  1ZSQ A;  1NTV A;  4F7U P;  5JHH A;  3P6A A;  2DLW A;  3MPX A;  2LKO A;  2L2I A;  1ZC4 B;  3O96 A;  1LB1 A;  2N23 A;  4HAY B;  4DBB A;  3PVU A;  4HAT B;  2D9X A;  1M7E A;  1BWN A;  2D4Q A;  2Z0O A;  2BCJ A;  5J3Y A;  1Z87 A;  1V88 A;  3TO1 A;  1WGQ A;  3SV1 A;  3WA0 A;  4MK0 A;  3KRW A;  1K5G B;  1BAK A;  4HDQ A;  3TW1 A;  2N0Y A;  3AU4 A;  3QBV B;  2UVM A;  4KHB B;  3LJU X;  2HTH B;  2R09 A;  1MIZ B;  1NI2 A;  4PNK A;  3ODO A;  1RJ2 A;  2QKM A;  2KCJ A;  1BTK A;  4MT7 A;  3CXB B;  1N3H A;  2D11 A;  1P3R A;  3FEH A;  2LOX A;  1PMS A;  3KRX A;  3WYF B;  3A98 B;  2EJ8 A;  5L81 A;  4Z2N A;  1WJ1 A;  3PVL A;  1FHO A;  1OY2 A;  3VOQ A;  2P8V A;  3HW2 B;  1UNP A;  1U5G A;  2W2X D;  1MK9 B;  1W1D A;  4K17 A;  2DYN A;  3CIK A;  3TVV A;  2LG1 A;  5C79 A;  2K2U A;  1OQN A;  2K00 A;  1ZC3 B;  4BBK A;  4WVF B;  2KGX B;  4GPT B;  2RGN B;  4NY0 A;  5KCV A;  5JP4 A;  1V5U A;  3PSC A;  4DXA B;  1TJ6 A;  3PZD A;  3PEG A;  2CY4 A;  2DX5 A;  2Q13 A;  1AQC A;  4YON A;  3HK0 A;  3AJ4 A;  3ML4 A;  1XKE A;  3HQC A;  3ODX A;  1NTY A;  4GXB A;  2YF0 A;  1PFJ A;  2IYB A;  2DHI A;  2I1J A;  3SNH A;  3GYO A;  5LOP B;  2AEH A;  4PQ0 A;  2OQB A;  2M38 A;  2UZR A;  1MIX A;  2P0H A;  2DA0 A;  3P7Z A;  2CAY A;  4EJN A;  1FHX A;  5HE1 A;  1V61 A;  3NSU A;  1KZ7 A;  2LUL A;  2YS1 A;  2ELB A;  1X1G A;  2Z0Q A;  4YL8 A;  3U8Z A;  5HE3 A;  1SGH A;  2FJL A;  2X18 A;  3SO6 A;  4ZRK A;  2K2J A;  1TQZ A;  1X1F A;  4Z2M B;  2EMT A;  1AWE A;  3OAN A;  3UZT A;  2J0K A;  1SHC A;  3A8P A;  2YRY A;  3DXD A;  2W2X C;  1DBH A;  4K2O A;  2Y7B A;  3V5W A;  2CRF A;  5FI0 A;  5D3V A;  3D8D A;  2GCL A;  2XQN M;  4F7H A;  2YT0 A;  4ZRI A;  1MK7 B;  1GC6 A;  3KY9 A;  1V5P A;  1XOD A;  3GYP A;  1I2H A;  1ZVR A;  4WJ7 A;  1X11 A;  2DKQ A;  1M7R A;  2DHJ A;  1XX0 A;  1DDM A;  3PG7 A;  1E5W A;  5DH9 B;  2Y8G A;  1U5F A;  2M14 A;  1W1H A;  2ELA A;  3SYX A;  2KUP A;  4HDO A;  1ZM0 A;  4K81 A;  1U5E A;  2HE7 A;  2G35 A;  4EKU A;  2E2X A;  4GZU A;  1X86 A;  1FAO A;  4WSF A;  1J0W A;  1QC6 A;  1EVH A;  1K5D B;  1DRO A;  2W2W A;  1DDV A;  2YT1 A;  4CHJ A;  3RCP A;  1P6S A;  1UNR A;  2DX1 A;  2VRW B;  3KSY A;  1FB8 A;  1FHW A;  2DN6 A;  2D2Q A;  1XCG A;  2LOZ A;  4HAU B;  4HB4 B;  4GMX B;  4CYE A;  4HAZ B;  3D8F A;  4A5K A;  1FOE A;  1H10 A;  1U2B A;  1MKE A;  1TXD A;  3DXE A;  2PZ1 A;  1UNQ A;  1PLS A;  1OMW A;  1WVH A;  5C16 A;  5D3Y A;  2COD A;  4KVG B;  3MDB C;  2MKR A;  2GCJ A;  2VSZ A;  2VKI A;  2D9Z A;  5C6R A;  1UPQ A;  2V76 A;  2YVC A;  2D9Y A;  2RUK B;  3PVW A;  2Y8F A;  3F5R A;  3FM8 C;  4HB0 B;  4MY6 A;  3ULC A;  4TYZ A;  4HAX B;  1QQG A;  4IAP A;  1EF1 A;  2NZ8 B;  1XD4 A;  2GS0 A;  4HB2 B;  4HAW B;  3PP2 A;  3VIA A;  2ROV A;  5LON B;  5DI9 B;  1IRS A;  4XWX A;  1EAZ A;  1U27 A;  2J0J A;  2QKL A;  2RLO A;  1UPR A;  1DYN A;  3QIJ A;  5HE0 A;  4NSW A;  4K2P A;  2MWN B;  4CHM A;  2YSZ A;  4L6E A;  2DHK A;  1ISN A;  4B6H A;  4A6K A;  5C5B A;  4GMV A;  3ODW A;  5DHF B;  1EGX A;  5KQ1 A;  2YS5 A;  3AU5 A;  5C5B B;  2JP2 A;  2MDX A;  4GN1 A;  2R0D A;  4HAV B;  5D27 A;  2COC A;  3FSS A;  2AL6 A;  2DFK A;  1MAI A;  3T06 A;  4P7I A;  2DYQ A;  1FGY A;  4KAX B;  3ULB A;  4H8S A;  1I7A A;  1KI1 B;  1RRP B;  2OTX A;  1V5M A;  4F7G A;  5J3Q A;  5CLQ B;  1H4R A;  3DXC A;  1NU2 A;  4Y94 A;  3KZ1 A;  2ZPY A;  5DHA B;  1MPH A;  5HE2 A;  2EC1 A;  4HB3 B;  5CLL B;  1Y19 B;  4KHA A;  1GG3 A;  2H7D A;  2EMS A;  3D8E A;  2P0F A;  5FI1 A;  5D3W A;  4IFS A;  4D0N B;  4EMO A;  2Z0P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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