1MI1A

Crystal structure of the ph-beach domain of human neurobeachin
Total Genus 111
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
111
sequence length
414
structure length
414
Chain Sequence
GPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDSAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSTLSWLVRIEPFTTFFLNANDGKFDHPDRTFSSVARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYNLGVREDEVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDPVLREAMEAQIQNFGQTPSQLLIEPHPPR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Neurobeachin
total genus 111
structure length 414
sequence length 414
chains with identical sequence B
ec nomenclature
pdb deposition date 2002-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02138 Beach Beige/BEACH domain
A PF14844 PH_BEACH PH domain associated with Beige/BEACH
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1540.10 Mainly Alpha Orthogonal Bundle Neurobeachin; Chain: A, domain 1 BEACH domain 1mi1A02
2.30.29.40 Mainly Beta Roll PH-domain like PH domain-like; domain 1 1mi1A01
1T77A 1MI1A
chains in the Genus database with same CATH superfamily
4Z2MB 4YL8A 1T77A 1I7AA 4CHJA 2HE7A 4P7IA 1QQGA 2ROZB 2BCJA 1TXDA 1DDMA 2K00A 2H7EA 5JLJB 4EJNA 4NY0A 1UNQA 2G35A 3HK0A 1EAZA 1FGYA 5L81A 5D3WA 3GYPA 1WVHA 5FI0A 3ULCA 4GNKB 2P8VA 3FSSA 1NTVA 2COAA 2VKIA 5JHGA 1ISNA 2GCJA 5DHFB 4MY6A 3KSYA 1RRPB 1U27A 1Z87A 5KCVA 1U2BA 1W1DA 3U12A 4GMXB 2VSZA 1U5DA 3HIEA 4BBKA 1EGXA 1DYNA 5DHAB 1MAIA 4A6FB 1WGUA 2ELAA 1DROA 5KQ4A 5C16A 4DBBA 3ODWA 4PNKA 2I5CA 1OY2A 2DHKA 1N3HA 5HE0A 1MIZB 2YT1A 2DLWA 5CLLB 3QIJA 4QJ3B 1LB1A 4CSQA 2RNRB 1XODA 2FJUB 2R2YA 1ZVRA 2J0MA 4IFSA 2IFSA 4KHOA 1V88A 1X86A 5LOPB 1WI1A 4KHBB 2KIEA 4GN1A 4A5KA 2D9YA 3TVVA 1TJ6A 2COFA 1MPHA 1WG7A 2JP2A 3X23A 1Y19B 2Z0PA 2D2QA 2AL6A 3BINA 1W1HA 3M1IB 1NI2A 3DXCA 4TYZA 3A58A 3A8QA 4EKUA 5HE2A 1GC6A 1P5TA 4F7HA 2X18A 4OSNA 4D0NB 2LULA 1OQNA 3AJ4A 2Q13A 3TO1A 2Z14A 5D3VA 5C5BB 2V76A 2YSZA 3B77A 4KVGB 2EJ8A 1WJ1A 4GZUA 1KZGA 4B6HA 2RVBB 1PMSA 3UZTA 1AQCA 4WJ7A 2DHJA 1ZM0A 1MK7B 4GXBA 1TQZA 2KUQA 4EMOA 2D4QA 2DYQA 2QKMA 2RSGA 1X1GA 1Y5OA 4DX90 1XKEA 2UZSA 2QKLA 4HB4B 1W1GA 1B55A 2P0DA 1V5UA 2DHIA 4DX8A 1KI1B 2D11A 3NSUA 3D8FA 3TW1A 2H7DA 1MIXA 1NTYA 3ZDTA 2YS1A 2Y7BA 5I2MA 3G9WA 3CXBB 3ML4A 4MK0A 1V61A 1U5GA 3QBVB 3WYFB 1PFJA 2L1CA 2DN6A 3PVLA 2EMSA 2RLOA 4HATB 4HB3B 2N23A 2RUKB 3T06A 3OANA 3RCPA 4NSWA 4KHAA 1V5PA 2KGXB 3OHMB 4IAPA 2ZPYA 3ODXA 2GUMA 2LG1A 1GC7A 2LOZA 2LYDA 2YT0A 4K17A 2J0JA 1X11A 5KQ1A 2RRFA 4HAZB 1U5EA 1RJ2A 3F0WA 3O96A 2Z59A 2DKQA 3WA0A 4HAUB 5C6RA 1KZ7A 3KY9A 3HSAA 4F7UP 1MKEA 1EVHA 3PZDA 5DH9B 1H10A 1AWEA 3MPXA 2PZ1A 2DKPA 3CIKA 4HAYB 2W2XC 2J59M 4CYEA 3ZVRA 2NBVA 5D3XA 4F7GA 2KUPA 1LW3A 4OT1A 2K2JA 3U8ZA 1P3RA 5GOWB 4DXAB 3BJIA 3HQCA 2Z13A 4HHVA 4PQ0A 5J3QA 3P6AA 1FHOA 1BTKA 5LONB 3ODOA 3V5WA 3KZ1A 1J0WA 1WGQA 3IVFA 4HB0B 5C79A 1XD4A 4ZRJA 5CLQB 2OTXA 3PP2A 2Z0OA 3PG7A 2W2XD 4HSIA 2KCJA 5JHHA 4C0AA 1MK9B 2DFKA 4ZRKA 1BAKA 1GG3A 4IOYX 1K5DB 1K5GB 1EF1A 2ELBA 2XQNM 3D8EA 1V5MA 2Y8FA 5FI1A 1WJMA 1SHCA 5M4YB 4A6KA 2RGNB 3AU4A 3PSCA 4HDOA 5EFXA 1BWNA 3SUZA 2D9WA 2D9ZA 4GPTB 1J19A 1ZYIA 2I5FA 2N0YA 2R0DA 1UEFA 2NMBA 2K2UA 1SGHA 3LJUX 3VIAA 2P0HA 3DCXA 2NZ8B 2ROVA 2DYNA 4HAXB 4QJ5B 4MT7A 5DI9B 2MKRA 5JP4A 1FOEA 2YT2A 4YONA 2GCLA 2UZRA 1H4RA 2GJYA 3D8DA 2HTHB 3KRXA 1X1FA 1Q67A 2KIGA 5D27A 2YRYA 5LG4B 1V89A 2YS3A 3TFMA 3PVWA 1UPRA 2LKOA 3PEGA 2K8EA 4ZRIA 3TCAA 4CHMA 4Y94A 4H8SA 4Z2NA 1ZSQA 3GYOA 5D3YA 1E5WA 3P7ZA 2LOXA 1NU2A 1QC6A 4KAXB 2E2XA 2R09A 3MDBC 2CY5A 3ULBA 4GOUA 4DIXA 1FHXA 3F5RA 1BTNA 4A6FA 3NWDA 4WVFB 4HB2B 3HW2B 2CY4A 3NW8A 2CRFA 4HAVB 1DDVA 1OMWA 2FJLA 3AU5A 1XX0A 2P0FA 4K2PA 2UVMA 2I1KA 1FHWA 1P6SA 3FVCA 3NWAA 1ZC3B 2CAYA 4A6HA 5HE3A 1XCGA 2CODA 2YS5A 4HDQA 1DBHA 4K81A 5I2SA 1U29A 5DIFB 3U7DA 4WSFA 2YVCA 1M7RA 4L1RA 2MFQA 3NWFA 1ZC4B 1UNRA 1I2HA 4KHBA 1U5FA 2VRWB 4TKNA 3SO6A 5J3TA 3VOQA 3FM8C 1X05A 1UNPA 2M38A 3A8PA 2DA0A 2EMTA 4D6WA 2J0KA 3SV1A 2DTCA 3SYXA 2I1JA 5J3YA 4HAWB 4QXAB 2DX5A 5HE1A 2COCA 3PVUA 3SNHA 3QWMA 4GMVA 2Z0QA 3FEHA 2AEHA 3DXDA 5C5BA 3DXEA 2EC1A 1DDWA 2OQBA 1FB8A 1UPQA 3KRWA 2L2IA 2M14A 1FGZA 3A98B 1XR0B 2MWNB 4L6EA 4K2OA 1MI1A 2IYBA 1FAOA 2D10A 4XWXA 2D9VA 1PLSA 2D9XA 2DX1A 1M7EA 2W2WA 5IRSA 2ADZA 2KR0A 2MDXA 3N7CA 2ZKMX 2YF0A 2Z4DA 1IRSA 2K49A 2GS0A 4QJ4B 2Y8GA
chains in the Genus database with same CATH topology
1T77A 1MI1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T77 A;  1MI1 A; 
#chains in the Genus database with same CATH topology
 4Z2M B;  4YL8 A;  1T77 A;  1I7A A;  4CHJ A;  2HE7 A;  4P7I A;  1QQG A;  2ROZ B;  2BCJ A;  1TXD A;  1DDM A;  2K00 A;  2H7E A;  5JLJ B;  4EJN A;  4NY0 A;  1UNQ A;  2G35 A;  3HK0 A;  1EAZ A;  1FGY A;  5L81 A;  5D3W A;  3GYP A;  1WVH A;  5FI0 A;  3ULC A;  4GNK B;  2P8V A;  3FSS A;  1NTV A;  2COA A;  2VKI A;  5JHG A;  1ISN A;  2GCJ A;  5DHF B;  4MY6 A;  3KSY A;  1RRP B;  1U27 A;  1Z87 A;  5KCV A;  1U2B A;  1W1D A;  3U12 A;  4GMX B;  2VSZ A;  1U5D A;  3HIE A;  4BBK A;  1EGX A;  1DYN A;  5DHA B;  1MAI A;  4A6F B;  1WGU A;  2ELA A;  1DRO A;  5KQ4 A;  5C16 A;  4DBB A;  3ODW A;  4PNK A;  2I5C A;  1OY2 A;  2DHK A;  1N3H A;  5HE0 A;  1MIZ B;  2YT1 A;  2DLW A;  5CLL B;  3QIJ A;  4QJ3 B;  1LB1 A;  4CSQ A;  2RNR B;  1XOD A;  2FJU B;  2R2Y A;  1ZVR A;  2J0M A;  4IFS A;  2IFS A;  4KHO A;  1V88 A;  1X86 A;  5LOP B;  1WI1 A;  4KHB B;  2KIE A;  4GN1 A;  4A5K A;  2D9Y A;  3TVV A;  1TJ6 A;  2COF A;  1MPH A;  1WG7 A;  2JP2 A;  3X23 A;  1Y19 B;  2Z0P A;  2D2Q A;  2AL6 A;  3BIN A;  1W1H A;  3M1I B;  1NI2 A;  3DXC A;  4TYZ A;  3A58 A;  3A8Q A;  4EKU A;  5HE2 A;  1GC6 A;  1P5T A;  4F7H A;  2X18 A;  4OSN A;  4D0N B;  2LUL A;  1OQN A;  3AJ4 A;  2Q13 A;  3TO1 A;  2Z14 A;  5D3V A;  5C5B B;  2V76 A;  2YSZ A;  3B77 A;  4KVG B;  2EJ8 A;  1WJ1 A;  4GZU A;  1KZG A;  4B6H A;  2RVB B;  1PMS A;  3UZT A;  1AQC A;  4WJ7 A;  2DHJ A;  1ZM0 A;  1MK7 B;  4GXB A;  1TQZ A;  2KUQ A;  4EMO A;  2D4Q A;  2DYQ A;  2QKM A;  2RSG A;  1X1G A;  1Y5O A;  4DX9 0;  1XKE A;  2UZS A;  2QKL A;  4HB4 B;  1W1G A;  1B55 A;  2P0D A;  1V5U A;  2DHI A;  4DX8 A;  1KI1 B;  2D11 A;  3NSU A;  3D8F A;  3TW1 A;  2H7D A;  1MIX A;  1NTY A;  3ZDT A;  2YS1 A;  2Y7B A;  5I2M A;  3G9W A;  3CXB B;  3ML4 A;  4MK0 A;  1V61 A;  1U5G A;  3QBV B;  3WYF B;  1PFJ A;  2L1C A;  2DN6 A;  3PVL A;  2EMS A;  2RLO A;  4HAT B;  4HB3 B;  2N23 A;  2RUK B;  3T06 A;  3OAN A;  3RCP A;  4NSW A;  4KHA A;  1V5P A;  2KGX B;  3OHM B;  4IAP A;  2ZPY A;  3ODX A;  2GUM A;  2LG1 A;  1GC7 A;  2LOZ A;  2LYD A;  2YT0 A;  4K17 A;  2J0J A;  1X11 A;  5KQ1 A;  2RRF A;  4HAZ B;  1U5E A;  1RJ2 A;  3F0W A;  3O96 A;  2Z59 A;  2DKQ A;  3WA0 A;  4HAU B;  5C6R A;  1KZ7 A;  3KY9 A;  3HSA A;  4F7U P;  1MKE A;  1EVH A;  3PZD A;  5DH9 B;  1H10 A;  1AWE A;  3MPX A;  2PZ1 A;  2DKP A;  3CIK A;  4HAY B;  2W2X C;  2J59 M;  4CYE A;  3ZVR A;  2NBV A;  5D3X A;  4F7G A;  2KUP A;  1LW3 A;  4OT1 A;  2K2J A;  3U8Z A;  1P3R A;  5GOW B;  4DXA B;  3BJI A;  3HQC A;  2Z13 A;  4HHV A;  4PQ0 A;  5J3Q A;  3P6A A;  1FHO A;  1BTK A;  5LON B;  3ODO A;  3V5W A;  3KZ1 A;  1J0W A;  1WGQ A;  3IVF A;  4HB0 B;  5C79 A;  1XD4 A;  4ZRJ A;  5CLQ B;  2OTX A;  3PP2 A;  2Z0O A;  3PG7 A;  2W2X D;  4HSI A;  2KCJ A;  5JHH A;  4C0A A;  1MK9 B;  2DFK A;  4ZRK A;  1BAK A;  1GG3 A;  4IOY X;  1K5D B;  1K5G B;  1EF1 A;  2ELB A;  2XQN M;  3D8E A;  1V5M A;  2Y8F A;  5FI1 A;  1WJM A;  1SHC A;  5M4Y B;  4A6K A;  2RGN B;  3AU4 A;  3PSC A;  4HDO A;  5EFX A;  1BWN A;  3SUZ A;  2D9W A;  2D9Z A;  4GPT B;  1J19 A;  1ZYI A;  2I5F A;  2N0Y A;  2R0D A;  1UEF A;  2NMB A;  2K2U A;  1SGH A;  3LJU X;  3VIA A;  2P0H A;  3DCX A;  2NZ8 B;  2ROV A;  2DYN A;  4HAX B;  4QJ5 B;  4MT7 A;  5DI9 B;  2MKR A;  5JP4 A;  1FOE A;  2YT2 A;  4YON A;  2GCL A;  2UZR A;  1H4R A;  2GJY A;  3D8D A;  2HTH B;  3KRX A;  1X1F A;  1Q67 A;  2KIG A;  5D27 A;  2YRY A;  5LG4 B;  1V89 A;  2YS3 A;  3TFM A;  3PVW A;  1UPR A;  2LKO A;  3PEG A;  2K8E A;  4ZRI A;  3TCA A;  4CHM A;  4Y94 A;  4H8S A;  4Z2N A;  1ZSQ A;  3GYO A;  5D3Y A;  1E5W A;  3P7Z A;  2LOX A;  1NU2 A;  1QC6 A;  4KAX B;  2E2X A;  2R09 A;  3MDB C;  2CY5 A;  3ULB A;  4GOU A;  4DIX A;  1FHX A;  3F5R A;  1BTN A;  4A6F A;  3NWD A;  4WVF B;  4HB2 B;  3HW2 B;  2CY4 A;  3NW8 A;  2CRF A;  4HAV B;  1DDV A;  1OMW A;  2FJL A;  3AU5 A;  1XX0 A;  2P0F A;  4K2P A;  2UVM A;  2I1K A;  1FHW A;  1P6S A;  3FVC A;  3NWA A;  1ZC3 B;  2CAY A;  4A6H A;  5HE3 A;  1XCG A;  2COD A;  2YS5 A;  4HDQ A;  1DBH A;  4K81 A;  5I2S A;  1U29 A;  5DIF B;  3U7D A;  4WSF A;  2YVC A;  1M7R A;  4L1R A;  2MFQ A;  3NWF A;  1ZC4 B;  1UNR A;  1I2H A;  4KHB A;  1U5F A;  2VRW B;  4TKN A;  3SO6 A;  5J3T A;  3VOQ A;  3FM8 C;  1X05 A;  1UNP A;  2M38 A;  3A8P A;  2DA0 A;  2EMT A;  4D6W A;  2J0K A;  3SV1 A;  2DTC A;  3SYX A;  2I1J A;  5J3Y A;  4HAW B;  4QXA B;  2DX5 A;  5HE1 A;  2COC A;  3PVU A;  3SNH A;  3QWM A;  4GMV A;  2Z0Q A;  3FEH A;  2AEH A;  3DXD A;  5C5B A;  3DXE A;  2EC1 A;  1DDW A;  2OQB A;  1FB8 A;  1UPQ A;  3KRW A;  2L2I A;  2M14 A;  1FGZ A;  3A98 B;  1XR0 B;  2MWN B;  4L6E A;  4K2O A;  1MI1 A;  2IYB A;  1FAO A;  2D10 A;  4XWX A;  2D9V A;  1PLS A;  2D9X A;  2DX1 A;  1M7E A;  2W2W A;  5IRS A;  2ADZ A;  2KR0 A;  2MDX A;  3N7C A;  2ZKM X;  2YF0 A;  2Z4D A;  1IRS A;  2K49 A;  2GS0 A;  4QJ4 B;  2Y8G A; 
#chains in the Genus database with same CATH homology
 1T77 A;  1MI1 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...