1W1DA

Crystal structure of the pdk1 pleckstrin homology (ph) domain bound to inositol (1,3,4,5)-tetrakisphosphate
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
143
structure length
143
Chain Sequence
PLGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRYQS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insights Into the Regulation of Pdk1 by Phosphoinositides and Inositol Phosphates
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1
total genus 38
structure length 143
sequence length 143
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2004-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14593 PH_3 PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1w1dA00
1J19A 3DXDA 3QBVB 2RLOA 2EC1A 1MK9B 2LULA 2FJLA 3SYXA 3ZDTA 2VRWB 2XQNM 1DDWA 3ULCA 4D0NB 3QWMA 1BTNA 2DFKA 1WGQA 2D10A 1PFJA 3VOQA 2R0DA 4C0AA 1TJ6A 3PEGA 2W2XD 2W2XC 3PG7A 2DTCA 2LKOA 4GMXB 1DDVA 3PVWA 4EJNA 1X86A 1GC6A 3ODWA 3MPXA 3ODOA 1ZM0A 3CIKA 1Z87A 3P7ZA 2D9WA 2M14A 1LB1A 2P0FA 2I1JA 1FHWA 1XX0A 3FEHA 1M7RA 1V5PA 2GCLA 4KAXB 2RSGA 4TYZA 4HDOA 4NY0A 2GJYA 1TXDA 4GMVA 3WYFB 3KRXA 2KGXB 1U29A 2ADZA 4K17A 1EGXA 3T06A 4WVFB 4MY6A 2RNRB 5FI1A 1P3RA 2Z0PA 2D9XA 1B55A 2D9VA 2OTXA 3ZVRA 1X11A 4IFSA 3UZTA 1IRSA 4K2OA 2N23A 3KSYA 2Z0QA 1UNRA 1UPRA 3AU5A 1WGUA 2H7DA 2P0HA 3PSCA 4KVGB 3KRWA 4KHOA 2CAYA 3PP2A 1W1HA 2IYBA 1GC7A 1WVHA 2Y8FA 1J0WA 1EVHA 2YS3A 1XODA 3TFMA 3X23A 4ZRKA 5C5BB 3DXEA 3SV1A 2OQBA 3VIAA 1UNPA 5JLJB 2RUKB 4F7UP 4DX8A 5D3YA 1PMSA 1OMWA 2VSZA 1FGYA 2EMSA 3ODXA 2D4QA 2JP2A 1MAIA 2AEHA 3O96A 5C79A 2J0JA 5GOWB 4ZRJA 2DKQA 4WJ7A 3P6AA 2COAA 1W1DA 3RCPA 4PQ0A 1FHOA 3TVVA 2MKRA 2D2QA 1XR0B 1Y19B 2KCJA 3A8QA 2J0MA 1OQNA 2CY5A 2QKLA 3TCAA 1KI1B 4KHAA 3ULBA 5JP4A 3BJIA 2EJ8A 1GG3A 4GPTB 2UZRA 5EFXA 1Q67A 1EAZA 2MWNB 5D3WA 1KZ7A 1K5GB 1DDMA 3N7CA 4HATB 4HAXB 2GCJA 4Y94A 2RVBB 2E2XA 2MDXA 4F7GA 1BTKA 3A8PA 1K5DB 1V5MA 3MDBC 2YS5A 2Z0OA 4IOYX 2H7EA 1AQCA 5KCVA 3U8ZA 2UZSA 1H4RA 3PVUA 2CRFA 2MFQA 1P6SA 2Y8GA 1SGHA 2NMBA 5CLQB 4BBKA 2M38A 4HB2B 2PZ1A 4B6HA 2YRYA 4Z2MB 3GYPA 3QIJA 2P8VA 4HAZB 2KUPA 1P5TA 1X1GA 4IAPA 5J3YA 1FGZA 2QKMA 4HHVA 2BCJA 1QC6A 2K2JA 2YF0A 4F7HA 2DYNA 4A6FA 5JHHA 1ISNA 5DHAB 1AWEA 4WSFA 5KQ1A 1WJ1A 2ELBA 5HE1A 2DHIA 1N3HA 2P0DA 2J0KA 3V5WA 3NSUA 2YS1A 2ELAA 4HDQA 4L6EA 5L81A 1X1FA 1X05A 4NSWA 1EF1A 3TW1A 2D9ZA 2LYDA 1V89A 1FAOA 3FM8C 1MIXA 1U2BA 3D8DA 2LG1A 1RRPB 3KY9A 2HTHB 1U5FA 3AU4A 4HB3B 5D3VA 4GZUA 1MKEA 2VKIA 5D3XA 5J3TA 4MK0A 1WG7A 1XD4A 1U27A 4HAYB 2EMTA 2IFSA 3GYOA 3HQCA 4GXBA 1TQZA 1V5UA 2I1KA 1U5DA 4A5KA 2YT0A 5LONB 5C6RA 1MIZB 1ZC3B 4P7IA 2K00A 2Q13A 2DX1A 1OY2A 2D9YA 2L2IA 2DN6A 3D8EA 2HE7A 2DX5A 2YVCA 5LOPB 3A98B 1MK7B 5D27A 4HAWB 3BINA 3F0WA 1FOEA 2N0YA 3SO6A 5CLLB 3ML4A 1NI2A 2X18A 4A6FB 2V76A 2LOZA 5DH9B 2YT1A 1NTYA 2RGNB 5KQ4A 5HE2A 4EMOA 5HE3A 2K2UA 4HB0B 1NTVA 3F5RA 1DBHA 4YONA 1BWNA 3AJ4A 3OANA 3U7DA 3M1IB 1XCGA 1H10A 1Y5OA 2DA0A 2DHJA 1V88A 2AL6A 1UEFA 3HW2B 4YL8A 2LOXA 2Y7BA 1DROA 1RJ2A 1M7EA 1QQGA 4TKNA 5JHGA 3G9WA 2D11A 4GN1A 3SNHA 3CXBB 2DYQA 5DIFB 2ROZB 2DHKA 1NU2A 1U5EA 3IVFA 1MPHA 4HAVB 1V61A 3SUZA 4K81A 4Z2NA 3HK0A 2DLWA 4CYEA 1FB8A 2R09A 4XWXA 4CHJA 1DYNA 1I7AA 2I5CA 1U5GA 2DKPA 1W1GA 4DXAB 1WJMA 2CODA 2I5FA 2UVMA 1KZGA 2NZ8B 3PVLA 5DI9B 4MT7A 4KHBB 4DX90 2J59M 1BAKA 2L1CA 1XKEA 2ROVA 1WI1A 1ZSQA 5J3QA 3PZDA 2ZPYA 1ZC4B 2CY4A 4K2PA 5FI0A 4DBBA 1UNQA 4HAUB 1UPQA 3FSSA 1LW3A 4HB4B 2COFA 3TO1A 4H8SA 4A6KA 4CHMA 5C16A 1ZVRA 1PLSA 1I2HA 3WA0A 3DXCA 1SHCA 3D8FA 5HE0A 4ZRIA 4A6HA 2GS0A 3LJUX 1E5WA 2YSZA 5DHFB 4PNKA 4EKUA 3KZ1A 2W2WA 2COCA 5C5BA 1FHXA 2G35A
chains in the Genus database with same CATH superfamily
1J19A 3DXDA 3QBVB 2RLOA 2EC1A 1MK9B 2LULA 2FJLA 3SYXA 3ZDTA 2VRWB 2XQNM 1DDWA 3ULCA 4D0NB 4QJ3B 2Z59A 3QWMA 1BTNA 2DFKA 1WGQA 2D10A 1PFJA 3VOQA 2R0DA 4C0AA 1TJ6A 3PEGA 2W2XD 2ZKMX 2W2XC 3PG7A 2DTCA 2LKOA 4GMXB 1DDVA 3PVWA 4EJNA 1X86A 1GC6A 3ODWA 3MPXA 3ODOA 1ZM0A 3CIKA 1Z87A 3P7ZA 2D9WA 2M14A 1LB1A 1MI1A 2P0FA 2I1JA 1FHWA 1XX0A 3FEHA 1M7RA 1V5PA 2GCLA 2K49A 4KAXB 2RSGA 4TYZA 4HDOA 4NY0A 2GJYA 1TXDA 4GMVA 3WYFB 3KRXA 2KGXB 1U29A 2ADZA 4K17A 1EGXA 3T06A 4WVFB 4MY6A 2RNRB 5FI1A 1P3RA 2Z0PA 2D9XA 1B55A 2D9VA 2OTXA 3ZVRA 1X11A 4IFSA 3UZTA 1IRSA 4K2OA 2N23A 3KSYA 2Z0QA 1UNRA 1UPRA 3AU5A 1WGUA 2H7DA 2P0HA 3DCXA 3PSCA 4KVGB 2G35A 3KRWA 4KHOA 2CAYA 3PP2A 1W1HA 2IYBA 1GC7A 1WVHA 2Y8FA 5I2SA 2R2YA 1J0WA 1EVHA 2YS3A 1XODA 3TFMA 3X23A 4ZRKA 5C5BB 3DXEA 3SV1A 2OQBA 3VIAA 1UNPA 5JLJB 2RUKB 4F7UP 4DX8A 5D3YA 1PMSA 1OMWA 2VSZA 1FGYA 2EMSA 3ODXA 2D4QA 2FJUB 2JP2A 1MAIA 2AEHA 3O96A 5C79A 2J0JA 5GOWB 4ZRJA 2DKQA 4WJ7A 3P6AA 2COAA 1W1DA 3RCPA 4PQ0A 1FHOA 3TVVA 2MKRA 2D2QA 1XR0B 1Y19B 2KCJA 3A8QA 2J0MA 1OQNA 2CY5A 2QKLA 3TCAA 3OHMB 1KI1B 4KHAA 3ULBA 5JP4A 3BJIA 2EJ8A 1GG3A 4GPTB 2UZRA 5EFXA 3NW8A 1Q67A 1EAZA 2KR0A 2MWNB 5D3WA 1KZ7A 1K5GB 1DDMA 3N7CA 2KIEA 4L1RA 4HATB 3U12A 4HAXB 2GCJA 4Y94A 2RVBB 2E2XA 2MDXA 4F7GA 1BTKA 3A8PA 1K5DB 1V5MA 3MDBC 2YS5A 2Z0OA 4IOYX 2H7EA 1AQCA 5KCVA 3U8ZA 3HIEA 2UZSA 1T77A 1H4RA 3PVUA 2CRFA 4GNKB 2MFQA 1P6SA 2Y8GA 1SGHA 2NMBA 5CLQB 4BBKA 2M38A 5LG4B 4HB2B 2PZ1A 4B6HA 2YRYA 4Z2MB 3GYPA 3QIJA 2P8VA 4HAZB 2KUPA 1P5TA 1X1GA 4IAPA 5J3YA 1FGZA 2QKMA 4HHVA 2BCJA 1QC6A 3B77A 2K2JA 2YF0A 4F7HA 2DYNA 4A6FA 5JHHA 1ISNA 5DHAB 1AWEA 4WSFA 5KQ1A 1WJ1A 2ELBA 5HE1A 2DHIA 1N3HA 2P0DA 2Z14A 2J0KA 3V5WA 3NSUA 2YS1A 5IRSA 2ELAA 4HDQA 4L6EA 2KUQA 5L81A 2Z13A 1X1FA 1X05A 4NSWA 1EF1A 3TW1A 3FVCA 2D9ZA 2LYDA 1V89A 1FAOA 3FM8C 4OSNA 1MIXA 1U2BA 3D8DA 2LG1A 1RRPB 3KY9A 2HTHB 1U5FA 3AU4A 4HB3B 5D3VA 2K8EA 1MKEA 2VKIA 4GZUA 5D3XA 4QXAB 5J3TA 4MK0A 1WG7A 1XD4A 1U27A 4HAYB 2EMTA 2IFSA 3GYOA 3HQCA 4GXBA 1TQZA 1V5UA 2I1KA 1U5DA 4A5KA 2YT0A 5LONB 4KHBA 5C6RA 1MIZB 4D6WA 1ZC3B 4P7IA 2K00A 2Q13A 2DX1A 1OY2A 2NBVA 2D9YA 2L2IA 2DN6A 3D8EA 2HE7A 2DX5A 2YT2A 2YVCA 5LOPB 3A98B 3A58A 1MK7B 5D27A 4HAWB 3BINA 3F0WA 4OT1A 1FOEA 2N0YA 3SO6A 5CLLB 3ML4A 1NI2A 2X18A 4A6FB 2V76A 2LOZA 5DH9B 2YT1A 1NTYA 2RGNB 5KQ4A 5HE2A 4EMOA 5HE3A 2K2UA 4HB0B 1NTVA 3F5RA 1DBHA 4YONA 1BWNA 3AJ4A 3OANA 3U7DA 3M1IB 1XCGA 1H10A 4CSQA 1Y5OA 2DA0A 2DHJA 1V88A 2AL6A 1UEFA 3HW2B 4YL8A 2LOXA 2Y7BA 1DROA 1RJ2A 1M7EA 1QQGA 4TKNA 5JHGA 3G9WA 2D11A 4GN1A 3SNHA 3CXBB 2DYQA 5DIFB 1ZYIA 2ROZB 2DHKA 3NWAA 1NU2A 1U5EA 3IVFA 1MPHA 5I2MA 4HAVB 1V61A 3SUZA 4K81A 4Z2NA 3HK0A 2DLWA 2Z4DA 4CYEA 1FB8A 2R09A 4XWXA 4CHJA 1DYNA 4HSIA 1I7AA 2I5CA 1U5GA 2DKPA 1W1GA 4DXAB 1WJMA 2CODA 2I5FA 2UVMA 1KZGA 2NZ8B 4QJ4B 3PVLA 5DI9B 4MT7A 4KHBB 4DX90 2J59M 1BAKA 2L1CA 1XKEA 2ROVA 1WI1A 1ZSQA 4QJ5B 5J3QA 3PZDA 2ZPYA 1ZC4B 2CY4A 4K2PA 5FI0A 4DBBA 1UNQA 2GUMA 4HAUB 1UPQA 3FSSA 1LW3A 4HB4B 2COFA 3NWFA 3TO1A 4H8SA 4A6KA 4CHMA 5M4YB 5C16A 1ZVRA 3HSAA 1PLSA 1I2HA 3NWDA 3WA0A 2RRFA 3DXCA 1SHCA 3D8FA 5HE0A 4ZRIA 4A6HA 2GS0A 3LJUX 1E5WA 2YSZA 4GOUA 5DHFB 4PNKA 4EKUA 3KZ1A 4DIXA 2W2WA 2COCA 5C5BA 1FHXA 2KIGA
chains in the Genus database with same CATH topology
1J19A 3DXDA 3QBVB 2RLOA 2EC1A 1MK9B 2LULA 2FJLA 3SYXA 3ZDTA 2VRWB 2XQNM 1DDWA 3ULCA 4D0NB 3QWMA 1BTNA 2DFKA 1WGQA 2D10A 1PFJA 3VOQA 2R0DA 4C0AA 1TJ6A 3PEGA 2W2XD 2W2XC 3PG7A 2DTCA 2LKOA 4GMXB 1DDVA 3PVWA 4EJNA 1X86A 1GC6A 3ODWA 3MPXA 3ODOA 1ZM0A 3CIKA 1Z87A 3P7ZA 2D9WA 2M14A 1LB1A 2P0FA 2I1JA 1FHWA 1XX0A 3FEHA 1M7RA 1V5PA 2GCLA 4KAXB 2RSGA 4TYZA 4HDOA 4NY0A 2GJYA 1TXDA 4GMVA 3WYFB 3KRXA 2KGXB 1U29A 2ADZA 4K17A 1EGXA 3T06A 4WVFB 4MY6A 2RNRB 5FI1A 1P3RA 2Z0PA 2D9XA 1B55A 2D9VA 2OTXA 3ZVRA 1X11A 4IFSA 3UZTA 1IRSA 4K2OA 2N23A 3KSYA 2Z0QA 1UNRA 1UPRA 3AU5A 1WGUA 2H7DA 2P0HA 3PSCA 4KVGB 3KRWA 4KHOA 2CAYA 3PP2A 1W1HA 2IYBA 1GC7A 1WVHA 2Y8FA 1J0WA 1EVHA 2YS3A 1XODA 3TFMA 3X23A 4ZRKA 5C5BB 3DXEA 3SV1A 2OQBA 3VIAA 1UNPA 5JLJB 2RUKB 4F7UP 4DX8A 5D3YA 1PMSA 1OMWA 2VSZA 1FGYA 2EMSA 3ODXA 2D4QA 2JP2A 1MAIA 2AEHA 3O96A 5C79A 2J0JA 5GOWB 4ZRJA 2DKQA 4WJ7A 3P6AA 2COAA 1W1DA 3RCPA 4PQ0A 1FHOA 3TVVA 2MKRA 2D2QA 1XR0B 1Y19B 2KCJA 3A8QA 2J0MA 1OQNA 2CY5A 2QKLA 3TCAA 1KI1B 4KHAA 3ULBA 5JP4A 3BJIA 2EJ8A 1GG3A 4GPTB 2UZRA 5EFXA 1Q67A 1EAZA 2MWNB 5D3WA 1KZ7A 1K5GB 1DDMA 3N7CA 4HATB 4HAXB 2GCJA 4Y94A 2RVBB 2E2XA 2MDXA 4F7GA 1BTKA 3A8PA 1K5DB 1V5MA 3MDBC 2YS5A 2Z0OA 4IOYX 2H7EA 1AQCA 5KCVA 3U8ZA 2UZSA 1H4RA 3PVUA 2CRFA 2MFQA 1P6SA 2Y8GA 1SGHA 2NMBA 5CLQB 4BBKA 2M38A 4HB2B 2PZ1A 4B6HA 2YRYA 4Z2MB 3GYPA 3QIJA 2P8VA 4HAZB 2KUPA 1P5TA 1X1GA 4IAPA 5J3YA 1FGZA 2QKMA 4HHVA 2BCJA 1QC6A 2K2JA 2YF0A 4F7HA 2DYNA 4A6FA 5JHHA 1ISNA 5DHAB 1AWEA 4WSFA 5KQ1A 1WJ1A 2ELBA 5HE1A 2DHIA 1N3HA 2P0DA 2J0KA 3V5WA 3NSUA 2YS1A 2ELAA 4HDQA 4L6EA 5L81A 1X1FA 1X05A 4NSWA 1EF1A 3TW1A 2D9ZA 2LYDA 1V89A 1FAOA 3FM8C 1MIXA 1U2BA 3D8DA 2LG1A 1RRPB 3KY9A 2HTHB 1U5FA 3AU4A 4HB3B 5D3VA 4GZUA 1MKEA 2VKIA 5D3XA 5J3TA 4MK0A 1WG7A 1XD4A 1U27A 4HAYB 2EMTA 2IFSA 3GYOA 3HQCA 4GXBA 1TQZA 1V5UA 2I1KA 1U5DA 4A5KA 2YT0A 5LONB 5C6RA 1MIZB 1ZC3B 4P7IA 2K00A 2Q13A 2DX1A 1OY2A 2D9YA 2L2IA 2DN6A 3D8EA 2HE7A 2DX5A 2YVCA 5LOPB 3A98B 1MK7B 5D27A 4HAWB 3BINA 3F0WA 1FOEA 2N0YA 3SO6A 5CLLB 3ML4A 1NI2A 2X18A 4A6FB 2V76A 2LOZA 5DH9B 2YT1A 1NTYA 2RGNB 5KQ4A 5HE2A 4EMOA 5HE3A 2K2UA 4HB0B 1NTVA 3F5RA 1DBHA 4YONA 1BWNA 3AJ4A 3OANA 3U7DA 3M1IB 1XCGA 1H10A 1Y5OA 2DA0A 2DHJA 1V88A 2AL6A 1UEFA 3HW2B 4YL8A 2LOXA 2Y7BA 1DROA 1RJ2A 1M7EA 1QQGA 4TKNA 5JHGA 3G9WA 2D11A 4GN1A 3SNHA 3CXBB 2DYQA 5DIFB 2ROZB 2DHKA 1NU2A 1U5EA 3IVFA 1MPHA 4HAVB 1V61A 3SUZA 4K81A 4Z2NA 3HK0A 2DLWA 4CYEA 1FB8A 2R09A 4XWXA 4CHJA 1DYNA 1I7AA 2I5CA 1U5GA 2DKPA 1W1GA 4DXAB 1WJMA 2CODA 2I5FA 2UVMA 1KZGA 2NZ8B 3PVLA 5DI9B 4MT7A 4KHBB 4DX90 2J59M 1BAKA 2L1CA 1XKEA 2ROVA 1WI1A 1ZSQA 5J3QA 3PZDA 2ZPYA 1ZC4B 2CY4A 4K2PA 5FI0A 4DBBA 1UNQA 4HAUB 1UPQA 3FSSA 1LW3A 4HB4B 2COFA 3TO1A 4H8SA 4A6KA 4CHMA 5C16A 1ZVRA 1PLSA 1I2HA 3WA0A 3DXCA 1SHCA 3D8FA 5HE0A 4ZRIA 4A6HA 2GS0A 3LJUX 1E5WA 2YSZA 5DHFB 4PNKA 4EKUA 3KZ1A 2W2WA 2COCA 5C5BA 1FHXA 2G35A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1J19 A;  3DXD A;  3QBV B;  2RLO A;  2EC1 A;  1MK9 B;  2LUL A;  2FJL A;  3SYX A;  3ZDT A;  2VRW B;  2XQN M;  1DDW A;  3ULC A;  4D0N B;  3QWM A;  1BTN A;  2DFK A;  1WGQ A;  2D10 A;  1PFJ A;  3VOQ A;  2R0D A;  4C0A A;  1TJ6 A;  3PEG A;  2W2X D;  2W2X C;  3PG7 A;  2DTC A;  2LKO A;  4GMX B;  1DDV A;  3PVW A;  4EJN A;  1X86 A;  1GC6 A;  3ODW A;  3MPX A;  3ODO A;  1ZM0 A;  3CIK A;  1Z87 A;  3P7Z A;  2D9W A;  2M14 A;  1LB1 A;  2P0F A;  2I1J A;  1FHW A;  1XX0 A;  3FEH A;  1M7R A;  1V5P A;  2GCL A;  4KAX B;  2RSG A;  4TYZ A;  4HDO A;  4NY0 A;  2GJY A;  1TXD A;  4GMV A;  3WYF B;  3KRX A;  2KGX B;  1U29 A;  2ADZ A;  4K17 A;  1EGX A;  3T06 A;  4WVF B;  4MY6 A;  2RNR B;  5FI1 A;  1P3R A;  2Z0P A;  2D9X A;  1B55 A;  2D9V A;  2OTX A;  3ZVR A;  1X11 A;  4IFS A;  3UZT A;  1IRS A;  4K2O A;  2N23 A;  3KSY A;  2Z0Q A;  1UNR A;  1UPR A;  3AU5 A;  1WGU A;  2H7D A;  2P0H A;  3PSC A;  4KVG B;  3KRW A;  4KHO A;  2CAY A;  3PP2 A;  1W1H A;  2IYB A;  1GC7 A;  1WVH A;  2Y8F A;  1J0W A;  1EVH A;  2YS3 A;  1XOD A;  3TFM A;  3X23 A;  4ZRK A;  5C5B B;  3DXE A;  3SV1 A;  2OQB A;  3VIA A;  1UNP A;  5JLJ B;  2RUK B;  4F7U P;  4DX8 A;  5D3Y A;  1PMS A;  1OMW A;  2VSZ A;  1FGY A;  2EMS A;  3ODX A;  2D4Q A;  2JP2 A;  1MAI A;  2AEH A;  3O96 A;  5C79 A;  2J0J A;  5GOW B;  4ZRJ A;  2DKQ A;  4WJ7 A;  3P6A A;  2COA A;  1W1D A;  3RCP A;  4PQ0 A;  1FHO A;  3TVV A;  2MKR A;  2D2Q A;  1XR0 B;  1Y19 B;  2KCJ A;  3A8Q A;  2J0M A;  1OQN A;  2CY5 A;  2QKL A;  3TCA A;  1KI1 B;  4KHA A;  3ULB A;  5JP4 A;  3BJI A;  2EJ8 A;  1GG3 A;  4GPT B;  2UZR A;  5EFX A;  1Q67 A;  1EAZ A;  2MWN B;  5D3W A;  1KZ7 A;  1K5G B;  1DDM A;  3N7C A;  4HAT B;  4HAX B;  2GCJ A;  4Y94 A;  2RVB B;  2E2X A;  2MDX A;  4F7G A;  1BTK A;  3A8P A;  1K5D B;  1V5M A;  3MDB C;  2YS5 A;  2Z0O A;  4IOY X;  2H7E A;  1AQC A;  5KCV A;  3U8Z A;  2UZS A;  1H4R A;  3PVU A;  2CRF A;  2MFQ A;  1P6S A;  2Y8G A;  1SGH A;  2NMB A;  5CLQ B;  4BBK A;  2M38 A;  4HB2 B;  2PZ1 A;  4B6H A;  2YRY A;  4Z2M B;  3GYP A;  3QIJ A;  2P8V A;  4HAZ B;  2KUP A;  1P5T A;  1X1G A;  4IAP A;  5J3Y A;  1FGZ A;  2QKM A;  4HHV A;  2BCJ A;  1QC6 A;  2K2J A;  2YF0 A;  4F7H A;  2DYN A;  4A6F A;  5JHH A;  1ISN A;  5DHA B;  1AWE A;  4WSF A;  5KQ1 A;  1WJ1 A;  2ELB A;  5HE1 A;  2DHI A;  1N3H A;  2P0D A;  2J0K A;  3V5W A;  3NSU A;  2YS1 A;  2ELA A;  4HDQ A;  4L6E A;  5L81 A;  1X1F A;  1X05 A;  4NSW A;  1EF1 A;  3TW1 A;  2D9Z A;  2LYD A;  1V89 A;  1FAO A;  3FM8 C;  1MIX A;  1U2B A;  3D8D A;  2LG1 A;  1RRP B;  3KY9 A;  2HTH B;  1U5F A;  3AU4 A;  4HB3 B;  5D3V A;  4GZU A;  1MKE A;  2VKI A;  5D3X A;  5J3T A;  4MK0 A;  1WG7 A;  1XD4 A;  1U27 A;  4HAY B;  2EMT A;  2IFS A;  3GYO A;  3HQC A;  4GXB A;  1TQZ A;  1V5U A;  2I1K A;  1U5D A;  4A5K A;  2YT0 A;  5LON B;  5C6R A;  1MIZ B;  1ZC3 B;  4P7I A;  2K00 A;  2Q13 A;  2DX1 A;  1OY2 A;  2D9Y A;  2L2I A;  2DN6 A;  3D8E A;  2HE7 A;  2DX5 A;  2YVC A;  5LOP B;  3A98 B;  1MK7 B;  5D27 A;  4HAW B;  3BIN A;  3F0W A;  1FOE A;  2N0Y A;  3SO6 A;  5CLL B;  3ML4 A;  1NI2 A;  2X18 A;  4A6F B;  2V76 A;  2LOZ A;  5DH9 B;  2YT1 A;  1NTY A;  2RGN B;  5KQ4 A;  5HE2 A;  4EMO A;  5HE3 A;  2K2U A;  4HB0 B;  1NTV A;  3F5R A;  1DBH A;  4YON A;  1BWN A;  3AJ4 A;  3OAN A;  3U7D A;  3M1I B;  1XCG A;  1H10 A;  1Y5O A;  2DA0 A;  2DHJ A;  1V88 A;  2AL6 A;  1UEF A;  3HW2 B;  4YL8 A;  2LOX A;  2Y7B A;  1DRO A;  1RJ2 A;  1M7E A;  1QQG A;  4TKN A;  5JHG A;  3G9W A;  2D11 A;  4GN1 A;  3SNH A;  3CXB B;  2DYQ A;  5DIF B;  2ROZ B;  2DHK A;  1NU2 A;  1U5E A;  3IVF A;  1MPH A;  4HAV B;  1V61 A;  3SUZ A;  4K81 A;  4Z2N A;  3HK0 A;  2DLW A;  4CYE A;  1FB8 A;  2R09 A;  4XWX A;  4CHJ A;  1DYN A;  1I7A A;  2I5C A;  1U5G A;  2DKP A;  1W1G A;  4DXA B;  1WJM A;  2COD A;  2I5F A;  2UVM A;  1KZG A;  2NZ8 B;  3PVL A;  5DI9 B;  4MT7 A;  4KHB B;  4DX9 0;  2J59 M;  1BAK A;  2L1C A;  1XKE A;  2ROV A;  1WI1 A;  1ZSQ A;  5J3Q A;  3PZD A;  2ZPY A;  1ZC4 B;  2CY4 A;  4K2P A;  5FI0 A;  4DBB A;  1UNQ A;  4HAU B;  1UPQ A;  3FSS A;  1LW3 A;  4HB4 B;  2COF A;  3TO1 A;  4H8S A;  4A6K A;  4CHM A;  5C16 A;  1ZVR A;  1PLS A;  1I2H A;  3WA0 A;  3DXC A;  1SHC A;  3D8F A;  5HE0 A;  4ZRI A;  4A6H A;  2GS0 A;  3LJU X;  1E5W A;  2YSZ A;  5DHF B;  4PNK A;  4EKU A;  3KZ1 A;  2W2W A;  2COC A;  5C5B A;  1FHX A;  2G35 A; 
#chains in the Genus database with same CATH topology
 1J19 A;  3DXD A;  3QBV B;  2RLO A;  2EC1 A;  1MK9 B;  2LUL A;  2FJL A;  3SYX A;  3ZDT A;  2VRW B;  2XQN M;  1DDW A;  3ULC A;  4D0N B;  4QJ3 B;  2Z59 A;  3QWM A;  1BTN A;  2DFK A;  1WGQ A;  2D10 A;  1PFJ A;  3VOQ A;  2R0D A;  4C0A A;  1TJ6 A;  3PEG A;  2W2X D;  2ZKM X;  2W2X C;  3PG7 A;  2DTC A;  2LKO A;  4GMX B;  1DDV A;  3PVW A;  4EJN A;  1X86 A;  1GC6 A;  3ODW A;  3MPX A;  3ODO A;  1ZM0 A;  3CIK A;  1Z87 A;  3P7Z A;  2D9W A;  2M14 A;  1LB1 A;  1MI1 A;  2P0F A;  2I1J A;  1FHW A;  1XX0 A;  3FEH A;  1M7R A;  1V5P A;  2GCL A;  2K49 A;  4KAX B;  2RSG A;  4TYZ A;  4HDO A;  4NY0 A;  2GJY A;  1TXD A;  4GMV A;  3WYF B;  3KRX A;  2KGX B;  1U29 A;  2ADZ A;  4K17 A;  1EGX A;  3T06 A;  4WVF B;  4MY6 A;  2RNR B;  5FI1 A;  1P3R A;  2Z0P A;  2D9X A;  1B55 A;  2D9V A;  2OTX A;  3ZVR A;  1X11 A;  4IFS A;  3UZT A;  1IRS A;  4K2O A;  2N23 A;  3KSY A;  2Z0Q A;  1UNR A;  1UPR A;  3AU5 A;  1WGU A;  2H7D A;  2P0H A;  3DCX A;  3PSC A;  4KVG B;  2G35 A;  3KRW A;  4KHO A;  2CAY A;  3PP2 A;  1W1H A;  2IYB A;  1GC7 A;  1WVH A;  2Y8F A;  5I2S A;  2R2Y A;  1J0W A;  1EVH A;  2YS3 A;  1XOD A;  3TFM A;  3X23 A;  4ZRK A;  5C5B B;  3DXE A;  3SV1 A;  2OQB A;  3VIA A;  1UNP A;  5JLJ B;  2RUK B;  4F7U P;  4DX8 A;  5D3Y A;  1PMS A;  1OMW A;  2VSZ A;  1FGY A;  2EMS A;  3ODX A;  2D4Q A;  2FJU B;  2JP2 A;  1MAI A;  2AEH A;  3O96 A;  5C79 A;  2J0J A;  5GOW B;  4ZRJ A;  2DKQ A;  4WJ7 A;  3P6A A;  2COA A;  1W1D A;  3RCP A;  4PQ0 A;  1FHO A;  3TVV A;  2MKR A;  2D2Q A;  1XR0 B;  1Y19 B;  2KCJ A;  3A8Q A;  2J0M A;  1OQN A;  2CY5 A;  2QKL A;  3TCA A;  3OHM B;  1KI1 B;  4KHA A;  3ULB A;  5JP4 A;  3BJI A;  2EJ8 A;  1GG3 A;  4GPT B;  2UZR A;  5EFX A;  3NW8 A;  1Q67 A;  1EAZ A;  2KR0 A;  2MWN B;  5D3W A;  1KZ7 A;  1K5G B;  1DDM A;  3N7C A;  2KIE A;  4L1R A;  4HAT B;  3U12 A;  4HAX B;  2GCJ A;  4Y94 A;  2RVB B;  2E2X A;  2MDX A;  4F7G A;  1BTK A;  3A8P A;  1K5D B;  1V5M A;  3MDB C;  2YS5 A;  2Z0O A;  4IOY X;  2H7E A;  1AQC A;  5KCV A;  3U8Z A;  3HIE A;  2UZS A;  1T77 A;  1H4R A;  3PVU A;  2CRF A;  4GNK B;  2MFQ A;  1P6S A;  2Y8G A;  1SGH A;  2NMB A;  5CLQ B;  4BBK A;  2M38 A;  5LG4 B;  4HB2 B;  2PZ1 A;  4B6H A;  2YRY A;  4Z2M B;  3GYP A;  3QIJ A;  2P8V A;  4HAZ B;  2KUP A;  1P5T A;  1X1G A;  4IAP A;  5J3Y A;  1FGZ A;  2QKM A;  4HHV A;  2BCJ A;  1QC6 A;  3B77 A;  2K2J A;  2YF0 A;  4F7H A;  2DYN A;  4A6F A;  5JHH A;  1ISN A;  5DHA B;  1AWE A;  4WSF A;  5KQ1 A;  1WJ1 A;  2ELB A;  5HE1 A;  2DHI A;  1N3H A;  2P0D A;  2Z14 A;  2J0K A;  3V5W A;  3NSU A;  2YS1 A;  5IRS A;  2ELA A;  4HDQ A;  4L6E A;  2KUQ A;  5L81 A;  2Z13 A;  1X1F A;  1X05 A;  4NSW A;  1EF1 A;  3TW1 A;  3FVC A;  2D9Z A;  2LYD A;  1V89 A;  1FAO A;  3FM8 C;  4OSN A;  1MIX A;  1U2B A;  3D8D A;  2LG1 A;  1RRP B;  3KY9 A;  2HTH B;  1U5F A;  3AU4 A;  4HB3 B;  5D3V A;  2K8E A;  1MKE A;  2VKI A;  4GZU A;  5D3X A;  4QXA B;  5J3T A;  4MK0 A;  1WG7 A;  1XD4 A;  1U27 A;  4HAY B;  2EMT A;  2IFS A;  3GYO A;  3HQC A;  4GXB A;  1TQZ A;  1V5U A;  2I1K A;  1U5D A;  4A5K A;  2YT0 A;  5LON B;  4KHB A;  5C6R A;  1MIZ B;  4D6W A;  1ZC3 B;  4P7I A;  2K00 A;  2Q13 A;  2DX1 A;  1OY2 A;  2NBV A;  2D9Y A;  2L2I A;  2DN6 A;  3D8E A;  2HE7 A;  2DX5 A;  2YT2 A;  2YVC A;  5LOP B;  3A98 B;  3A58 A;  1MK7 B;  5D27 A;  4HAW B;  3BIN A;  3F0W A;  4OT1 A;  1FOE A;  2N0Y A;  3SO6 A;  5CLL B;  3ML4 A;  1NI2 A;  2X18 A;  4A6F B;  2V76 A;  2LOZ A;  5DH9 B;  2YT1 A;  1NTY A;  2RGN B;  5KQ4 A;  5HE2 A;  4EMO A;  5HE3 A;  2K2U A;  4HB0 B;  1NTV A;  3F5R A;  1DBH A;  4YON A;  1BWN A;  3AJ4 A;  3OAN A;  3U7D A;  3M1I B;  1XCG A;  1H10 A;  4CSQ A;  1Y5O A;  2DA0 A;  2DHJ A;  1V88 A;  2AL6 A;  1UEF A;  3HW2 B;  4YL8 A;  2LOX A;  2Y7B A;  1DRO A;  1RJ2 A;  1M7E A;  1QQG A;  4TKN A;  5JHG A;  3G9W A;  2D11 A;  4GN1 A;  3SNH A;  3CXB B;  2DYQ A;  5DIF B;  1ZYI A;  2ROZ B;  2DHK A;  3NWA A;  1NU2 A;  1U5E A;  3IVF A;  1MPH A;  5I2M A;  4HAV B;  1V61 A;  3SUZ A;  4K81 A;  4Z2N A;  3HK0 A;  2DLW A;  2Z4D A;  4CYE A;  1FB8 A;  2R09 A;  4XWX A;  4CHJ A;  1DYN A;  4HSI A;  1I7A A;  2I5C A;  1U5G A;  2DKP A;  1W1G A;  4DXA B;  1WJM A;  2COD A;  2I5F A;  2UVM A;  1KZG A;  2NZ8 B;  4QJ4 B;  3PVL A;  5DI9 B;  4MT7 A;  4KHB B;  4DX9 0;  2J59 M;  1BAK A;  2L1C A;  1XKE A;  2ROV A;  1WI1 A;  1ZSQ A;  4QJ5 B;  5J3Q A;  3PZD A;  2ZPY A;  1ZC4 B;  2CY4 A;  4K2P A;  5FI0 A;  4DBB A;  1UNQ A;  2GUM A;  4HAU B;  1UPQ A;  3FSS A;  1LW3 A;  4HB4 B;  2COF A;  3NWF A;  3TO1 A;  4H8S A;  4A6K A;  4CHM A;  5M4Y B;  5C16 A;  1ZVR A;  3HSA A;  1PLS A;  1I2H A;  3NWD A;  3WA0 A;  2RRF A;  3DXC A;  1SHC A;  3D8F A;  5HE0 A;  4ZRI A;  4A6H A;  2GS0 A;  3LJU X;  1E5W A;  2YSZ A;  4GOU A;  5DHF B;  4PNK A;  4EKU A;  3KZ1 A;  4DIX A;  2W2W A;  2COC A;  5C5B A;  1FHX A;  2KIG A; 
#chains in the Genus database with same CATH homology
 1J19 A;  3DXD A;  3QBV B;  2RLO A;  2EC1 A;  1MK9 B;  2LUL A;  2FJL A;  3SYX A;  3ZDT A;  2VRW B;  2XQN M;  1DDW A;  3ULC A;  4D0N B;  3QWM A;  1BTN A;  2DFK A;  1WGQ A;  2D10 A;  1PFJ A;  3VOQ A;  2R0D A;  4C0A A;  1TJ6 A;  3PEG A;  2W2X D;  2W2X C;  3PG7 A;  2DTC A;  2LKO A;  4GMX B;  1DDV A;  3PVW A;  4EJN A;  1X86 A;  1GC6 A;  3ODW A;  3MPX A;  3ODO A;  1ZM0 A;  3CIK A;  1Z87 A;  3P7Z A;  2D9W A;  2M14 A;  1LB1 A;  2P0F A;  2I1J A;  1FHW A;  1XX0 A;  3FEH A;  1M7R A;  1V5P A;  2GCL A;  4KAX B;  2RSG A;  4TYZ A;  4HDO A;  4NY0 A;  2GJY A;  1TXD A;  4GMV A;  3WYF B;  3KRX A;  2KGX B;  1U29 A;  2ADZ A;  4K17 A;  1EGX A;  3T06 A;  4WVF B;  4MY6 A;  2RNR B;  5FI1 A;  1P3R A;  2Z0P A;  2D9X A;  1B55 A;  2D9V A;  2OTX A;  3ZVR A;  1X11 A;  4IFS A;  3UZT A;  1IRS A;  4K2O A;  2N23 A;  3KSY A;  2Z0Q A;  1UNR A;  1UPR A;  3AU5 A;  1WGU A;  2H7D A;  2P0H A;  3PSC A;  4KVG B;  3KRW A;  4KHO A;  2CAY A;  3PP2 A;  1W1H A;  2IYB A;  1GC7 A;  1WVH A;  2Y8F A;  1J0W A;  1EVH A;  2YS3 A;  1XOD A;  3TFM A;  3X23 A;  4ZRK A;  5C5B B;  3DXE A;  3SV1 A;  2OQB A;  3VIA A;  1UNP A;  5JLJ B;  2RUK B;  4F7U P;  4DX8 A;  5D3Y A;  1PMS A;  1OMW A;  2VSZ A;  1FGY A;  2EMS A;  3ODX A;  2D4Q A;  2JP2 A;  1MAI A;  2AEH A;  3O96 A;  5C79 A;  2J0J A;  5GOW B;  4ZRJ A;  2DKQ A;  4WJ7 A;  3P6A A;  2COA A;  1W1D A;  3RCP A;  4PQ0 A;  1FHO A;  3TVV A;  2MKR A;  2D2Q A;  1XR0 B;  1Y19 B;  2KCJ A;  3A8Q A;  2J0M A;  1OQN A;  2CY5 A;  2QKL A;  3TCA A;  1KI1 B;  4KHA A;  3ULB A;  5JP4 A;  3BJI A;  2EJ8 A;  1GG3 A;  4GPT B;  2UZR A;  5EFX A;  1Q67 A;  1EAZ A;  2MWN B;  5D3W A;  1KZ7 A;  1K5G B;  1DDM A;  3N7C A;  4HAT B;  4HAX B;  2GCJ A;  4Y94 A;  2RVB B;  2E2X A;  2MDX A;  4F7G A;  1BTK A;  3A8P A;  1K5D B;  1V5M A;  3MDB C;  2YS5 A;  2Z0O A;  4IOY X;  2H7E A;  1AQC A;  5KCV A;  3U8Z A;  2UZS A;  1H4R A;  3PVU A;  2CRF A;  2MFQ A;  1P6S A;  2Y8G A;  1SGH A;  2NMB A;  5CLQ B;  4BBK A;  2M38 A;  4HB2 B;  2PZ1 A;  4B6H A;  2YRY A;  4Z2M B;  3GYP A;  3QIJ A;  2P8V A;  4HAZ B;  2KUP A;  1P5T A;  1X1G A;  4IAP A;  5J3Y A;  1FGZ A;  2QKM A;  4HHV A;  2BCJ A;  1QC6 A;  2K2J A;  2YF0 A;  4F7H A;  2DYN A;  4A6F A;  5JHH A;  1ISN A;  5DHA B;  1AWE A;  4WSF A;  5KQ1 A;  1WJ1 A;  2ELB A;  5HE1 A;  2DHI A;  1N3H A;  2P0D A;  2J0K A;  3V5W A;  3NSU A;  2YS1 A;  2ELA A;  4HDQ A;  4L6E A;  5L81 A;  1X1F A;  1X05 A;  4NSW A;  1EF1 A;  3TW1 A;  2D9Z A;  2LYD A;  1V89 A;  1FAO A;  3FM8 C;  1MIX A;  1U2B A;  3D8D A;  2LG1 A;  1RRP B;  3KY9 A;  2HTH B;  1U5F A;  3AU4 A;  4HB3 B;  5D3V A;  4GZU A;  1MKE A;  2VKI A;  5D3X A;  5J3T A;  4MK0 A;  1WG7 A;  1XD4 A;  1U27 A;  4HAY B;  2EMT A;  2IFS A;  3GYO A;  3HQC A;  4GXB A;  1TQZ A;  1V5U A;  2I1K A;  1U5D A;  4A5K A;  2YT0 A;  5LON B;  5C6R A;  1MIZ B;  1ZC3 B;  4P7I A;  2K00 A;  2Q13 A;  2DX1 A;  1OY2 A;  2D9Y A;  2L2I A;  2DN6 A;  3D8E A;  2HE7 A;  2DX5 A;  2YVC A;  5LOP B;  3A98 B;  1MK7 B;  5D27 A;  4HAW B;  3BIN A;  3F0W A;  1FOE A;  2N0Y A;  3SO6 A;  5CLL B;  3ML4 A;  1NI2 A;  2X18 A;  4A6F B;  2V76 A;  2LOZ A;  5DH9 B;  2YT1 A;  1NTY A;  2RGN B;  5KQ4 A;  5HE2 A;  4EMO A;  5HE3 A;  2K2U A;  4HB0 B;  1NTV A;  3F5R A;  1DBH A;  4YON A;  1BWN A;  3AJ4 A;  3OAN A;  3U7D A;  3M1I B;  1XCG A;  1H10 A;  1Y5O A;  2DA0 A;  2DHJ A;  1V88 A;  2AL6 A;  1UEF A;  3HW2 B;  4YL8 A;  2LOX A;  2Y7B A;  1DRO A;  1RJ2 A;  1M7E A;  1QQG A;  4TKN A;  5JHG A;  3G9W A;  2D11 A;  4GN1 A;  3SNH A;  3CXB B;  2DYQ A;  5DIF B;  2ROZ B;  2DHK A;  1NU2 A;  1U5E A;  3IVF A;  1MPH A;  4HAV B;  1V61 A;  3SUZ A;  4K81 A;  4Z2N A;  3HK0 A;  2DLW A;  4CYE A;  1FB8 A;  2R09 A;  4XWX A;  4CHJ A;  1DYN A;  1I7A A;  2I5C A;  1U5G A;  2DKP A;  1W1G A;  4DXA B;  1WJM A;  2COD A;  2I5F A;  2UVM A;  1KZG A;  2NZ8 B;  3PVL A;  5DI9 B;  4MT7 A;  4KHB B;  4DX9 0;  2J59 M;  1BAK A;  2L1C A;  1XKE A;  2ROV A;  1WI1 A;  1ZSQ A;  5J3Q A;  3PZD A;  2ZPY A;  1ZC4 B;  2CY4 A;  4K2P A;  5FI0 A;  4DBB A;  1UNQ A;  4HAU B;  1UPQ A;  3FSS A;  1LW3 A;  4HB4 B;  2COF A;  3TO1 A;  4H8S A;  4A6K A;  4CHM A;  5C16 A;  1ZVR A;  1PLS A;  1I2H A;  3WA0 A;  3DXC A;  1SHC A;  3D8F A;  5HE0 A;  4ZRI A;  4A6H A;  2GS0 A;  3LJU X;  1E5W A;  2YSZ A;  5DHF B;  4PNK A;  4EKU A;  3KZ1 A;  2W2W A;  2COC A;  5C5B A;  1FHX A;  2G35 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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