2H7EA

Solution structure of the talin f3 domain in complex with a chimeric beta3 integrin-pip kinase peptide- minimized average structure
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
101
structure length
101
Chain Sequence
PLGSGVSFFLVKEKMKGKNKLVPRLLGITKESVMRVDEKTKEVIQEWSLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of integrin activation by talin
pubmed doi rcsb
molecule tags Structural protein
source organism Gallus gallus
molecule keywords Talin-1
total genus 17
structure length 101
sequence length 101
ec nomenclature
pdb deposition date 2006-06-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 2h7eA00
3PVWA 2GCJA 2D11A 1U5DA 2Z0OA 4HAUB 1OQNA 3KRWA 1V89A 1SHCA 1X05A 5CLQB 2YS5A 2W2XC 2J0KA 4GXBA 4GPTB 2D10A 1FHXA 3DXDA 3A8QA 5HE2A 5LOPB 2I1JA 1TJ6A 1W1DA 4HDOA 2YVCA 3BINA 3HW2B 5DIFB 2HTHB 2NMBA 2N23A 2K2UA 2K00A 3U8ZA 2GJYA 2MDXA 2P0HA 2KUPA 2COCA 3SNHA 5JP4A 3OANA 1IRSA 4PQ0A 3FM8C 2H7EA 3TVVA 1SGHA 4WVFB 2RSGA 1U2BA 4H8SA 4HAZB 3PVLA 5DHAB 5L81A 4DXAB 4EKUA 4PNKA 1NTVA 1M7RA 2NZ8B 4C0AA 5JHGA 1XR0B 3AU4A 2JP2A 5HE1A 4A5KA 2DYQA 4NSWA 2CODA 5DH9B 3P7ZA 2EJ8A 4XWXA 2K2JA 2VSZA 2EC1A 1MIZB 4MK0A 2DN6A 3M1IB 1X11A 1Z87A 5JHHA 1N3HA 1K5DB 1GC6A 1V88A 3MDBC 2YS1A 2RNRB 1PLSA 2QKLA 3ODWA 1MK9B 1WGQA 4KHOA 4HAYB 3O96A 3F5RA 1E5WA 4GN1A 1QQGA 2LOXA 4K17A 4YL8A 1WJ1A 1FHOA 3ULCA 1ZVRA 4F7GA 5D3XA 2D4QA 1FGYA 1TXDA 1P3RA 2VRWB 4HATB 5D3WA 4KVGB 4MT7A 1DROA 1DDVA 1BTNA 3HK0A 3TCAA 1BAKA 1UPRA 2OQBA 4Y94A 2J0MA 1I7AA 2M38A 4CYEA 1P6SA 2DHJA 4HAXB 5C5BB 3DXCA 1MKEA 4A6KA 2RGNB 2IFSA 5D3VA 4CHJA 1QC6A 4DX90 4F7HA 2DHIA 3PEGA 1RJ2A 3TO1A 2W2WA 3X23A 1UEFA 2RVBB 3ZVRA 2DKQA 3KSYA 2DLWA 2J59M 1ZC4B 4A6FB 5C79A 4A6HA 4KHBB 2CRFA 5HE3A 3AU5A 1WJMA 2I5FA 1U5GA 1I2HA 4ZRKA 2AEHA 2EMSA 4HAWB 1KZ7A 4HB4B 4IFSA 4HAVB 1J19A 2ELBA 1AQCA 2DYNA 1FB8A 1X1FA 2OTXA 5J3YA 2DHKA 2R0DA 2P8VA 3WA0A 1V61A 2QKMA 2ROVA 3D8DA 3UZTA 2GS0A 2KGXB 2FJLA 2J0JA 3ODOA 3U7DA 3A8PA 3PG7A 3F0WA 2ZPYA 3SV1A 2ADZA 2RUKB 4P7IA 2MFQA 5LONB 4KAXB 1MAIA 4HB2B 4NY0A 1X1GA 1KZGA 3PSCA 5C6RA 3PP2A 2KCJA 3SYXA 1W1GA 1TQZA 5J3TA 2M14A 1UPQA 4GMVA 1UNRA 5J3QA 2UZRA 1U5EA 3RCPA 4WSFA 1FGZA 5KQ4A 1H4RA 2W2XD 5JLJB 4HB3B 2YT0A 1OY2A 1GG3A 1AWEA 2X18A 2D9WA 4EMOA 4DX8A 3KZ1A 3P6AA 4YONA 3KY9A 3WYFB 5D3YA 1EGXA 2ELAA 1NU2A 2GCLA 1P5TA 3VOQA 5GOWB 3BJIA 2YS3A 1BWNA 1XCGA 1FOEA 4DBBA 3KRXA 1EAZA 4EJNA 1GC7A 3D8FA 1XX0A 2D9ZA 2I1KA 1FAOA 4GMXB 1Y5OA 4KHAA 1LW3A 5C5BA 1WI1A 1NI2A 4ZRJA 1Y19B 1MK7B 1XODA 4Z2MB 3SUZA 3LJUX 2UZSA 3HQCA 4TKNA 1W1HA 3TW1A 3V5WA 1BTKA 2BCJA 4A6FA 1MIXA 4IAPA 3N7CA 2AL6A 4B6HA 2Y8FA 3ULBA 1UNPA 1V5UA 3TFMA 5EFXA 3VIAA 5KCVA 2VKIA 1KI1B 2Z0PA 2P0FA 4CHMA 2YF0A 2COAA 4IOYX 3NSUA 5FI0A 2PZ1A 3MPXA 2V76A 2E2XA 5D27A 4HDQA 2DFKA 5CLLB 2DX1A 2R09A 1DYNA 3QBVB 3CIKA 3QWMA 4K2OA 4K81A 1OMWA 3QIJA 2Z0QA 2D2QA 2LYDA 2MKRA 2RLOA 1ZC3B 2DKPA 1U29A 1Q67A 1UNQA 4GZUA 2CAYA 4L6EA 4ZRIA 1U27A 3ODXA 2YSZA 5C16A 2MWNB 5KQ1A 4HHVA 1WVHA 3ML4A 1V5MA 3GYPA 1H10A 1DDMA 1DDWA 5FI1A 2D9VA 2YRYA 2I5CA 1RRPB 2DX5A 2Y8GA 1MPHA 2LG1A 1U5FA 3D8EA 3DXEA 1M7EA 2LULA 4WJ7A 2LKOA 3FSSA 2ROZB 4F7UP 3SO6A 2IYBA 1V5PA 1ZSQA 3CXBB 1ZM0A 1PMSA 3FEHA 3AJ4A 1K5GB 1WG7A 2DTCA 3ZDTA 1NTYA 4BBKA 4MY6A 2HE7A 4D0NB 4HB0B 3PVUA 2L1CA 3A98B 1DBHA 5HE0A 1FHWA 5DI9B 2YT1A 2LOZA 2UVMA 3PZDA 2H7DA 2EMTA 2CY4A 4K2PA 1WGUA 2D9XA 3IVFA 1PFJA 2L2IA 1B55A 2COFA 1EF1A 1X86A 2P0DA 2XQNM 4TYZA 1ISNA 2Q13A 1J0WA 2DA0A 1XD4A 3GYOA 2Y7BA 1EVHA 3T06A 1XKEA 3G9WA 2D9YA 5DHFB 2CY5A 2G35A 2N0YA 4Z2NA 1LB1A
chains in the Genus database with same CATH superfamily
3PVWA 2GCJA 2D11A 1U5DA 2Z0OA 4HAUB 1OQNA 3KRWA 1V89A 1SHCA 1X05A 5CLQB 2YS5A 2W2XC 2J0KA 4GXBA 4GPTB 2D10A 1FHXA 2RRFA 3DXDA 3A8QA 5HE2A 5LOPB 2I1JA 1TJ6A 1W1DA 4HDOA 2YVCA 3BINA 3HW2B 5DIFB 4CSQA 2HTHB 2NMBA 2N23A 2K2UA 2K00A 3U8ZA 2GJYA 2MDXA 2P0HA 2KUPA 2COCA 4HSIA 3SNHA 5JP4A 3OANA 1IRSA 2KR0A 4PQ0A 3FM8C 2H7EA 3TVVA 2Z13A 1SGHA 4WVFB 2RSGA 1U2BA 4H8SA 4HAZB 3PVLA 5DHAB 5L81A 4DXAB 4EKUA 4PNKA 1NTVA 1M7RA 2NZ8B 4C0AA 5JHGA 1XR0B 3AU4A 2JP2A 5HE1A 4A5KA 2DYQA 4NSWA 2CODA 5DH9B 3P7ZA 2EJ8A 4XWXA 2K2JA 2VSZA 4OSNA 2EC1A 1MIZB 4MK0A 2DN6A 3M1IB 1X11A 3U12A 1Z87A 5JHHA 1N3HA 1K5DB 1GC6A 3NWDA 1V88A 3MDBC 5LG4B 2YS1A 2RNRB 1PLSA 2QKLA 3ODWA 1MK9B 1WGQA 4KHOA 4HAYB 3O96A 3F5RA 1E5WA 4GN1A 1QQGA 2LOXA 4K17A 4YL8A 1WJ1A 1FHOA 3ULCA 1ZVRA 4F7GA 5D3XA 2D4QA 1FGYA 2Z14A 1TXDA 2NBVA 1P3RA 2VRWB 4HATB 5D3WA 4KVGB 4MT7A 1DROA 1DDVA 3NWFA 1BTNA 3HK0A 3TCAA 4QJ5B 1BAKA 1UPRA 2OQBA 4Y94A 2J0MA 1I7AA 2M38A 4CYEA 1P6SA 2DHJA 4HAXB 5C5BB 3DXCA 1MKEA 4A6KA 2RGNB 2IFSA 2Z4DA 5D3VA 4CHJA 1QC6A 4DX90 4KHBA 4F7HA 2DHIA 3PEGA 1RJ2A 3TO1A 2W2WA 3X23A 1UEFA 2RVBB 3ZVRA 2DKQA 3KSYA 3NWAA 2DLWA 2J59M 1ZC4B 4A6FB 5C79A 4A6HA 4KHBB 2CRFA 5HE3A 3AU5A 1WJMA 2I5FA 1U5GA 1I2HA 4D6WA 4ZRKA 2AEHA 2EMSA 4HAWB 1KZ7A 4HB4B 4IFSA 4HAVB 1J19A 2ELBA 1AQCA 2DYNA 1FB8A 1X1FA 2OTXA 2KIGA 5J3YA 2DHKA 2R0DA 2P8VA 3WA0A 1V61A 2QKMA 2ROVA 3D8DA 3UZTA 2FJUB 2GS0A 2KGXB 2FJLA 2J0JA 3ODOA 3U7DA 3A8PA 3PG7A 3F0WA 2ZPYA 3SV1A 2ADZA 2RUKB 4P7IA 2MFQA 5LONB 4KAXB 1MAIA 4HB2B 4NY0A 1X1GA 1KZGA 3PSCA 1MI1A 5C6RA 3PP2A 2KCJA 3SYXA 4DIXA 1W1GA 1TQZA 5J3TA 2M14A 1UPQA 4GMVA 1UNRA 5J3QA 2UZRA 1U5EA 3RCPA 4WSFA 1FGZA 5KQ4A 2KIEA 1H4RA 1T77A 2W2XD 5JLJB 4HB3B 2YT0A 2ZKMX 1OY2A 1GG3A 1AWEA 2X18A 2D9WA 4EMOA 4DX8A 3KZ1A 3P6AA 3HIEA 4YONA 3KY9A 3WYFB 5D3YA 4QJ4B 1EGXA 2ELAA 1NU2A 2GCLA 1P5TA 3VOQA 5GOWB 3BJIA 2KUQA 4GOUA 2YS3A 1BWNA 1XCGA 1ZYIA 2YT2A 1FOEA 4DBBA 3KRXA 1EAZA 4EJNA 1GC7A 3D8FA 1XX0A 2D9ZA 3A58A 2I1KA 1FAOA 4GMXB 1Y5OA 4KHAA 1LW3A 5C5BA 1WI1A 1NI2A 4ZRJA 1Y19B 1MK7B 5I2MA 1XODA 4Z2MB 3OHMB 3SUZA 4GNKB 3LJUX 2UZSA 3HQCA 4TKNA 1W1HA 3TW1A 3V5WA 1BTKA 2BCJA 4A6FA 1MIXA 4IAPA 3N7CA 2AL6A 4B6HA 2Y8FA 3ULBA 1UNPA 1V5UA 3TFMA 5EFXA 3VIAA 5KCVA 2VKIA 1KI1B 5M4YB 2Z0PA 2P0FA 4CHMA 2YF0A 2COAA 4QXAB 4IOYX 3NSUA 5FI0A 2K49A 5IRSA 2PZ1A 3MPXA 2V76A 2E2XA 5D27A 4HDQA 2DFKA 5CLLB 2DX1A 2R09A 2GUMA 1DYNA 3QBVB 3CIKA 3QWMA 4K2OA 4K81A 1OMWA 3QIJA 2Z0QA 2D2QA 2LYDA 2MKRA 2RLOA 1ZC3B 2DKPA 1U29A 1Q67A 1UNQA 4GZUA 2CAYA 4L6EA 4ZRIA 1U27A 3NW8A 4QJ3B 3ODXA 2YSZA 5C16A 2MWNB 5KQ1A 4HHVA 1WVHA 3ML4A 3DCXA 1V5MA 3GYPA 1H10A 5I2SA 1DDMA 1DDWA 5FI1A 2D9VA 2YRYA 2K8EA 2I5CA 1RRPB 2DX5A 2Y8GA 1MPHA 2LG1A 4OT1A 1U5FA 3D8EA 3DXEA 1M7EA 2LULA 4WJ7A 2LKOA 3FSSA 2ROZB 4F7UP 2R2YA 3SO6A 2IYBA 1V5PA 1ZSQA 3CXBB 1ZM0A 1PMSA 3FEHA 3AJ4A 1K5GB 1WG7A 2DTCA 3ZDTA 1NTYA 2Z59A 4BBKA 4MY6A 2HE7A 3B77A 4D0NB 4HB0B 3PVUA 2L1CA 3A98B 1DBHA 5HE0A 1FHWA 5DI9B 2YT1A 2LOZA 2UVMA 3PZDA 2H7DA 2EMTA 2CY4A 4K2PA 1WGUA 2D9XA 3IVFA 1PFJA 2L2IA 4L1RA 1B55A 2COFA 1EF1A 1X86A 2P0DA 2XQNM 3FVCA 4TYZA 1ISNA 2Q13A 1J0WA 2DA0A 3HSAA 1XD4A 3GYOA 2Y7BA 1EVHA 3T06A 1XKEA 3G9WA 2D9YA 5DHFB 2CY5A 2G35A 2N0YA 4Z2NA 1LB1A
chains in the Genus database with same CATH topology
3PVWA 2GCJA 2D11A 1U5DA 2Z0OA 4HAUB 1OQNA 3KRWA 1V89A 1SHCA 1X05A 5CLQB 2YS5A 2W2XC 2J0KA 4GXBA 4GPTB 2D10A 1FHXA 3DXDA 3A8QA 5HE2A 5LOPB 2I1JA 1TJ6A 1W1DA 4HDOA 2YVCA 3BINA 3HW2B 5DIFB 2HTHB 2NMBA 2N23A 2K2UA 2K00A 3U8ZA 2GJYA 2MDXA 2P0HA 2KUPA 2COCA 3SNHA 5JP4A 3OANA 1IRSA 4PQ0A 3FM8C 2H7EA 3TVVA 1SGHA 4WVFB 2RSGA 1U2BA 4H8SA 4HAZB 3PVLA 5DHAB 5L81A 4DXAB 4EKUA 4PNKA 1NTVA 1M7RA 2NZ8B 4C0AA 5JHGA 1XR0B 3AU4A 2JP2A 5HE1A 4A5KA 2DYQA 4NSWA 2CODA 5DH9B 3P7ZA 2EJ8A 4XWXA 2K2JA 2VSZA 2EC1A 1MIZB 4MK0A 2DN6A 3M1IB 1X11A 1Z87A 5JHHA 1N3HA 1K5DB 1GC6A 1V88A 3MDBC 2YS1A 2RNRB 1PLSA 2QKLA 3ODWA 1MK9B 1WGQA 4KHOA 4HAYB 3O96A 3F5RA 1E5WA 4GN1A 1QQGA 2LOXA 4K17A 4YL8A 1WJ1A 1FHOA 3ULCA 1ZVRA 4F7GA 5D3XA 2D4QA 1FGYA 1TXDA 1P3RA 2VRWB 4HATB 5D3WA 4KVGB 4MT7A 1DROA 1DDVA 1BTNA 3HK0A 3TCAA 1BAKA 1UPRA 2OQBA 4Y94A 2J0MA 1I7AA 2M38A 4CYEA 1P6SA 2DHJA 4HAXB 5C5BB 3DXCA 1MKEA 4A6KA 2RGNB 2IFSA 5D3VA 4CHJA 1QC6A 4DX90 4F7HA 2DHIA 3PEGA 1RJ2A 3TO1A 2W2WA 3X23A 1UEFA 2RVBB 3ZVRA 2DKQA 3KSYA 2DLWA 2J59M 1ZC4B 4A6FB 5C79A 4A6HA 4KHBB 2CRFA 5HE3A 3AU5A 1WJMA 2I5FA 1U5GA 1I2HA 4ZRKA 2AEHA 2EMSA 4HAWB 1KZ7A 4HB4B 4IFSA 4HAVB 1J19A 2ELBA 1AQCA 2DYNA 1FB8A 1X1FA 2OTXA 5J3YA 2DHKA 2R0DA 2P8VA 3WA0A 1V61A 2QKMA 2ROVA 3D8DA 3UZTA 2GS0A 2KGXB 2FJLA 2J0JA 3ODOA 3U7DA 3A8PA 3PG7A 3F0WA 2ZPYA 3SV1A 2ADZA 2RUKB 4P7IA 2MFQA 5LONB 4KAXB 1MAIA 4HB2B 4NY0A 1X1GA 1KZGA 3PSCA 5C6RA 3PP2A 2KCJA 3SYXA 1W1GA 1TQZA 5J3TA 2M14A 1UPQA 4GMVA 1UNRA 5J3QA 2UZRA 1U5EA 3RCPA 4WSFA 1FGZA 5KQ4A 1H4RA 2W2XD 5JLJB 4HB3B 2YT0A 1OY2A 1GG3A 1AWEA 2X18A 2D9WA 4EMOA 4DX8A 3KZ1A 3P6AA 4YONA 3KY9A 3WYFB 5D3YA 1EGXA 2ELAA 1NU2A 2GCLA 1P5TA 3VOQA 5GOWB 3BJIA 2YS3A 1BWNA 1XCGA 1FOEA 4DBBA 3KRXA 1EAZA 4EJNA 1GC7A 3D8FA 1XX0A 2D9ZA 2I1KA 1FAOA 4GMXB 1Y5OA 4KHAA 1LW3A 5C5BA 1WI1A 1NI2A 4ZRJA 1Y19B 1MK7B 1XODA 4Z2MB 3SUZA 3LJUX 2UZSA 3HQCA 4TKNA 1W1HA 3TW1A 3V5WA 1BTKA 2BCJA 4A6FA 1MIXA 4IAPA 3N7CA 2AL6A 4B6HA 2Y8FA 3ULBA 1UNPA 1V5UA 3TFMA 5EFXA 3VIAA 5KCVA 2VKIA 1KI1B 2Z0PA 2P0FA 4CHMA 2YF0A 2COAA 4IOYX 3NSUA 5FI0A 2PZ1A 3MPXA 2V76A 2E2XA 5D27A 4HDQA 2DFKA 5CLLB 2DX1A 2R09A 1DYNA 3QBVB 3CIKA 3QWMA 4K2OA 4K81A 1OMWA 3QIJA 2Z0QA 2D2QA 2LYDA 2MKRA 2RLOA 1ZC3B 2DKPA 1U29A 1Q67A 1UNQA 4GZUA 2CAYA 4L6EA 4ZRIA 1U27A 3ODXA 2YSZA 5C16A 2MWNB 5KQ1A 4HHVA 1WVHA 3ML4A 1V5MA 3GYPA 1H10A 1DDMA 1DDWA 5FI1A 2D9VA 2YRYA 2I5CA 1RRPB 2DX5A 2Y8GA 1MPHA 2LG1A 1U5FA 3D8EA 3DXEA 1M7EA 2LULA 4WJ7A 2LKOA 3FSSA 2ROZB 4F7UP 3SO6A 2IYBA 1V5PA 1ZSQA 3CXBB 1ZM0A 1PMSA 3FEHA 3AJ4A 1K5GB 1WG7A 2DTCA 3ZDTA 1NTYA 4BBKA 4MY6A 2HE7A 4D0NB 4HB0B 3PVUA 2L1CA 3A98B 1DBHA 5HE0A 1FHWA 5DI9B 2YT1A 2LOZA 2UVMA 3PZDA 2H7DA 2EMTA 2CY4A 4K2PA 1WGUA 2D9XA 3IVFA 1PFJA 2L2IA 1B55A 2COFA 1EF1A 1X86A 2P0DA 2XQNM 4TYZA 1ISNA 2Q13A 1J0WA 2DA0A 1XD4A 3GYOA 2Y7BA 1EVHA 3T06A 1XKEA 3G9WA 2D9YA 5DHFB 2CY5A 2G35A 2N0YA 4Z2NA 1LB1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PVW A;  2GCJ A;  2D11 A;  1U5D A;  2Z0O A;  4HAU B;  1OQN A;  3KRW A;  1V89 A;  1SHC A;  1X05 A;  5CLQ B;  2YS5 A;  2W2X C;  2J0K A;  4GXB A;  4GPT B;  2D10 A;  1FHX A;  3DXD A;  3A8Q A;  5HE2 A;  5LOP B;  2I1J A;  1TJ6 A;  1W1D A;  4HDO A;  2YVC A;  3BIN A;  3HW2 B;  5DIF B;  2HTH B;  2NMB A;  2N23 A;  2K2U A;  2K00 A;  3U8Z A;  2GJY A;  2MDX A;  2P0H A;  2KUP A;  2COC A;  3SNH A;  5JP4 A;  3OAN A;  1IRS A;  4PQ0 A;  3FM8 C;  2H7E A;  3TVV A;  1SGH A;  4WVF B;  2RSG A;  1U2B A;  4H8S A;  4HAZ B;  3PVL A;  5DHA B;  5L81 A;  4DXA B;  4EKU A;  4PNK A;  1NTV A;  1M7R A;  2NZ8 B;  4C0A A;  5JHG A;  1XR0 B;  3AU4 A;  2JP2 A;  5HE1 A;  4A5K A;  2DYQ A;  4NSW A;  2COD A;  5DH9 B;  3P7Z A;  2EJ8 A;  4XWX A;  2K2J A;  2VSZ A;  2EC1 A;  1MIZ B;  4MK0 A;  2DN6 A;  3M1I B;  1X11 A;  1Z87 A;  5JHH A;  1N3H A;  1K5D B;  1GC6 A;  1V88 A;  3MDB C;  2YS1 A;  2RNR B;  1PLS A;  2QKL A;  3ODW A;  1MK9 B;  1WGQ A;  4KHO A;  4HAY B;  3O96 A;  3F5R A;  1E5W A;  4GN1 A;  1QQG A;  2LOX A;  4K17 A;  4YL8 A;  1WJ1 A;  1FHO A;  3ULC A;  1ZVR A;  4F7G A;  5D3X A;  2D4Q A;  1FGY A;  1TXD A;  1P3R A;  2VRW B;  4HAT B;  5D3W A;  4KVG B;  4MT7 A;  1DRO A;  1DDV A;  1BTN A;  3HK0 A;  3TCA A;  1BAK A;  1UPR A;  2OQB A;  4Y94 A;  2J0M A;  1I7A A;  2M38 A;  4CYE A;  1P6S A;  2DHJ A;  4HAX B;  5C5B B;  3DXC A;  1MKE A;  4A6K A;  2RGN B;  2IFS A;  5D3V A;  4CHJ A;  1QC6 A;  4DX9 0;  4F7H A;  2DHI A;  3PEG A;  1RJ2 A;  3TO1 A;  2W2W A;  3X23 A;  1UEF A;  2RVB B;  3ZVR A;  2DKQ A;  3KSY A;  2DLW A;  2J59 M;  1ZC4 B;  4A6F B;  5C79 A;  4A6H A;  4KHB B;  2CRF A;  5HE3 A;  3AU5 A;  1WJM A;  2I5F A;  1U5G A;  1I2H A;  4ZRK A;  2AEH A;  2EMS A;  4HAW B;  1KZ7 A;  4HB4 B;  4IFS A;  4HAV B;  1J19 A;  2ELB A;  1AQC A;  2DYN A;  1FB8 A;  1X1F A;  2OTX A;  5J3Y A;  2DHK A;  2R0D A;  2P8V A;  3WA0 A;  1V61 A;  2QKM A;  2ROV A;  3D8D A;  3UZT A;  2GS0 A;  2KGX B;  2FJL A;  2J0J A;  3ODO A;  3U7D A;  3A8P A;  3PG7 A;  3F0W A;  2ZPY A;  3SV1 A;  2ADZ A;  2RUK B;  4P7I A;  2MFQ A;  5LON B;  4KAX B;  1MAI A;  4HB2 B;  4NY0 A;  1X1G A;  1KZG A;  3PSC A;  5C6R A;  3PP2 A;  2KCJ A;  3SYX A;  1W1G A;  1TQZ A;  5J3T A;  2M14 A;  1UPQ A;  4GMV A;  1UNR A;  5J3Q A;  2UZR A;  1U5E A;  3RCP A;  4WSF A;  1FGZ A;  5KQ4 A;  1H4R A;  2W2X D;  5JLJ B;  4HB3 B;  2YT0 A;  1OY2 A;  1GG3 A;  1AWE A;  2X18 A;  2D9W A;  4EMO A;  4DX8 A;  3KZ1 A;  3P6A A;  4YON A;  3KY9 A;  3WYF B;  5D3Y A;  1EGX A;  2ELA A;  1NU2 A;  2GCL A;  1P5T A;  3VOQ A;  5GOW B;  3BJI A;  2YS3 A;  1BWN A;  1XCG A;  1FOE A;  4DBB A;  3KRX A;  1EAZ A;  4EJN A;  1GC7 A;  3D8F A;  1XX0 A;  2D9Z A;  2I1K A;  1FAO A;  4GMX B;  1Y5O A;  4KHA A;  1LW3 A;  5C5B A;  1WI1 A;  1NI2 A;  4ZRJ A;  1Y19 B;  1MK7 B;  1XOD A;  4Z2M B;  3SUZ A;  3LJU X;  2UZS A;  3HQC A;  4TKN A;  1W1H A;  3TW1 A;  3V5W A;  1BTK A;  2BCJ A;  4A6F A;  1MIX A;  4IAP A;  3N7C A;  2AL6 A;  4B6H A;  2Y8F A;  3ULB A;  1UNP A;  1V5U A;  3TFM A;  5EFX A;  3VIA A;  5KCV A;  2VKI A;  1KI1 B;  2Z0P A;  2P0F A;  4CHM A;  2YF0 A;  2COA A;  4IOY X;  3NSU A;  5FI0 A;  2PZ1 A;  3MPX A;  2V76 A;  2E2X A;  5D27 A;  4HDQ A;  2DFK A;  5CLL B;  2DX1 A;  2R09 A;  1DYN A;  3QBV B;  3CIK A;  3QWM A;  4K2O A;  4K81 A;  1OMW A;  3QIJ A;  2Z0Q A;  2D2Q A;  2LYD A;  2MKR A;  2RLO A;  1ZC3 B;  2DKP A;  1U29 A;  1Q67 A;  1UNQ A;  4GZU A;  2CAY A;  4L6E A;  4ZRI A;  1U27 A;  3ODX A;  2YSZ A;  5C16 A;  2MWN B;  5KQ1 A;  4HHV A;  1WVH A;  3ML4 A;  1V5M A;  3GYP A;  1H10 A;  1DDM A;  1DDW A;  5FI1 A;  2D9V A;  2YRY A;  2I5C A;  1RRP B;  2DX5 A;  2Y8G A;  1MPH A;  2LG1 A;  1U5F A;  3D8E A;  3DXE A;  1M7E A;  2LUL A;  4WJ7 A;  2LKO A;  3FSS A;  2ROZ B;  4F7U P;  3SO6 A;  2IYB A;  1V5P A;  1ZSQ A;  3CXB B;  1ZM0 A;  1PMS A;  3FEH A;  3AJ4 A;  1K5G B;  1WG7 A;  2DTC A;  3ZDT A;  1NTY A;  4BBK A;  4MY6 A;  2HE7 A;  4D0N B;  4HB0 B;  3PVU A;  2L1C A;  3A98 B;  1DBH A;  5HE0 A;  1FHW A;  5DI9 B;  2YT1 A;  2LOZ A;  2UVM A;  3PZD A;  2H7D A;  2EMT A;  2CY4 A;  4K2P A;  1WGU A;  2D9X A;  3IVF A;  1PFJ A;  2L2I A;  1B55 A;  2COF A;  1EF1 A;  1X86 A;  2P0D A;  2XQN M;  4TYZ A;  1ISN A;  2Q13 A;  1J0W A;  2DA0 A;  1XD4 A;  3GYO A;  2Y7B A;  1EVH A;  3T06 A;  1XKE A;  3G9W A;  2D9Y A;  5DHF B;  2CY5 A;  2G35 A;  2N0Y A;  4Z2N A;  1LB1 A; 
#chains in the Genus database with same CATH topology
 3PVW A;  2GCJ A;  2D11 A;  1U5D A;  2Z0O A;  4HAU B;  1OQN A;  3KRW A;  1V89 A;  1SHC A;  1X05 A;  5CLQ B;  2YS5 A;  2W2X C;  2J0K A;  4GXB A;  4GPT B;  2D10 A;  1FHX A;  2RRF A;  3DXD A;  3A8Q A;  5HE2 A;  5LOP B;  2I1J A;  1TJ6 A;  1W1D A;  4HDO A;  2YVC A;  3BIN A;  3HW2 B;  5DIF B;  4CSQ A;  2HTH B;  2NMB A;  2N23 A;  2K2U A;  2K00 A;  3U8Z A;  2GJY A;  2MDX A;  2P0H A;  2KUP A;  2COC A;  4HSI A;  3SNH A;  5JP4 A;  3OAN A;  1IRS A;  2KR0 A;  4PQ0 A;  3FM8 C;  2H7E A;  3TVV A;  2Z13 A;  1SGH A;  4WVF B;  2RSG A;  1U2B A;  4H8S A;  4HAZ B;  3PVL A;  5DHA B;  5L81 A;  4DXA B;  4EKU A;  4PNK A;  1NTV A;  1M7R A;  2NZ8 B;  4C0A A;  5JHG A;  1XR0 B;  3AU4 A;  2JP2 A;  5HE1 A;  4A5K A;  2DYQ A;  4NSW A;  2COD A;  5DH9 B;  3P7Z A;  2EJ8 A;  4XWX A;  2K2J A;  2VSZ A;  4OSN A;  2EC1 A;  1MIZ B;  4MK0 A;  2DN6 A;  3M1I B;  1X11 A;  3U12 A;  1Z87 A;  5JHH A;  1N3H A;  1K5D B;  1GC6 A;  3NWD A;  1V88 A;  3MDB C;  5LG4 B;  2YS1 A;  2RNR B;  1PLS A;  2QKL A;  3ODW A;  1MK9 B;  1WGQ A;  4KHO A;  4HAY B;  3O96 A;  3F5R A;  1E5W A;  4GN1 A;  1QQG A;  2LOX A;  4K17 A;  4YL8 A;  1WJ1 A;  1FHO A;  3ULC A;  1ZVR A;  4F7G A;  5D3X A;  2D4Q A;  1FGY A;  2Z14 A;  1TXD A;  2NBV A;  1P3R A;  2VRW B;  4HAT B;  5D3W A;  4KVG B;  4MT7 A;  1DRO A;  1DDV A;  3NWF A;  1BTN A;  3HK0 A;  3TCA A;  4QJ5 B;  1BAK A;  1UPR A;  2OQB A;  4Y94 A;  2J0M A;  1I7A A;  2M38 A;  4CYE A;  1P6S A;  2DHJ A;  4HAX B;  5C5B B;  3DXC A;  1MKE A;  4A6K A;  2RGN B;  2IFS A;  2Z4D A;  5D3V A;  4CHJ A;  1QC6 A;  4DX9 0;  4KHB A;  4F7H A;  2DHI A;  3PEG A;  1RJ2 A;  3TO1 A;  2W2W A;  3X23 A;  1UEF A;  2RVB B;  3ZVR A;  2DKQ A;  3KSY A;  3NWA A;  2DLW A;  2J59 M;  1ZC4 B;  4A6F B;  5C79 A;  4A6H A;  4KHB B;  2CRF A;  5HE3 A;  3AU5 A;  1WJM A;  2I5F A;  1U5G A;  1I2H A;  4D6W A;  4ZRK A;  2AEH A;  2EMS A;  4HAW B;  1KZ7 A;  4HB4 B;  4IFS A;  4HAV B;  1J19 A;  2ELB A;  1AQC A;  2DYN A;  1FB8 A;  1X1F A;  2OTX A;  2KIG A;  5J3Y A;  2DHK A;  2R0D A;  2P8V A;  3WA0 A;  1V61 A;  2QKM A;  2ROV A;  3D8D A;  3UZT A;  2FJU B;  2GS0 A;  2KGX B;  2FJL A;  2J0J A;  3ODO A;  3U7D A;  3A8P A;  3PG7 A;  3F0W A;  2ZPY A;  3SV1 A;  2ADZ A;  2RUK B;  4P7I A;  2MFQ A;  5LON B;  4KAX B;  1MAI A;  4HB2 B;  4NY0 A;  1X1G A;  1KZG A;  3PSC A;  1MI1 A;  5C6R A;  3PP2 A;  2KCJ A;  3SYX A;  4DIX A;  1W1G A;  1TQZ A;  5J3T A;  2M14 A;  1UPQ A;  4GMV A;  1UNR A;  5J3Q A;  2UZR A;  1U5E A;  3RCP A;  4WSF A;  1FGZ A;  5KQ4 A;  2KIE A;  1H4R A;  1T77 A;  2W2X D;  5JLJ B;  4HB3 B;  2YT0 A;  2ZKM X;  1OY2 A;  1GG3 A;  1AWE A;  2X18 A;  2D9W A;  4EMO A;  4DX8 A;  3KZ1 A;  3P6A A;  3HIE A;  4YON A;  3KY9 A;  3WYF B;  5D3Y A;  4QJ4 B;  1EGX A;  2ELA A;  1NU2 A;  2GCL A;  1P5T A;  3VOQ A;  5GOW B;  3BJI A;  2KUQ A;  4GOU A;  2YS3 A;  1BWN A;  1XCG A;  1ZYI A;  2YT2 A;  1FOE A;  4DBB A;  3KRX A;  1EAZ A;  4EJN A;  1GC7 A;  3D8F A;  1XX0 A;  2D9Z A;  3A58 A;  2I1K A;  1FAO A;  4GMX B;  1Y5O A;  4KHA A;  1LW3 A;  5C5B A;  1WI1 A;  1NI2 A;  4ZRJ A;  1Y19 B;  1MK7 B;  5I2M A;  1XOD A;  4Z2M B;  3OHM B;  3SUZ A;  4GNK B;  3LJU X;  2UZS A;  3HQC A;  4TKN A;  1W1H A;  3TW1 A;  3V5W A;  1BTK A;  2BCJ A;  4A6F A;  1MIX A;  4IAP A;  3N7C A;  2AL6 A;  4B6H A;  2Y8F A;  3ULB A;  1UNP A;  1V5U A;  3TFM A;  5EFX A;  3VIA A;  5KCV A;  2VKI A;  1KI1 B;  5M4Y B;  2Z0P A;  2P0F A;  4CHM A;  2YF0 A;  2COA A;  4QXA B;  4IOY X;  3NSU A;  5FI0 A;  2K49 A;  5IRS A;  2PZ1 A;  3MPX A;  2V76 A;  2E2X A;  5D27 A;  4HDQ A;  2DFK A;  5CLL B;  2DX1 A;  2R09 A;  2GUM A;  1DYN A;  3QBV B;  3CIK A;  3QWM A;  4K2O A;  4K81 A;  1OMW A;  3QIJ A;  2Z0Q A;  2D2Q A;  2LYD A;  2MKR A;  2RLO A;  1ZC3 B;  2DKP A;  1U29 A;  1Q67 A;  1UNQ A;  4GZU A;  2CAY A;  4L6E A;  4ZRI A;  1U27 A;  3NW8 A;  4QJ3 B;  3ODX A;  2YSZ A;  5C16 A;  2MWN B;  5KQ1 A;  4HHV A;  1WVH A;  3ML4 A;  3DCX A;  1V5M A;  3GYP A;  1H10 A;  5I2S A;  1DDM A;  1DDW A;  5FI1 A;  2D9V A;  2YRY A;  2K8E A;  2I5C A;  1RRP B;  2DX5 A;  2Y8G A;  1MPH A;  2LG1 A;  4OT1 A;  1U5F A;  3D8E A;  3DXE A;  1M7E A;  2LUL A;  4WJ7 A;  2LKO A;  3FSS A;  2ROZ B;  4F7U P;  2R2Y A;  3SO6 A;  2IYB A;  1V5P A;  1ZSQ A;  3CXB B;  1ZM0 A;  1PMS A;  3FEH A;  3AJ4 A;  1K5G B;  1WG7 A;  2DTC A;  3ZDT A;  1NTY A;  2Z59 A;  4BBK A;  4MY6 A;  2HE7 A;  3B77 A;  4D0N B;  4HB0 B;  3PVU A;  2L1C A;  3A98 B;  1DBH A;  5HE0 A;  1FHW A;  5DI9 B;  2YT1 A;  2LOZ A;  2UVM A;  3PZD A;  2H7D A;  2EMT A;  2CY4 A;  4K2P A;  1WGU A;  2D9X A;  3IVF A;  1PFJ A;  2L2I A;  4L1R A;  1B55 A;  2COF A;  1EF1 A;  1X86 A;  2P0D A;  2XQN M;  3FVC A;  4TYZ A;  1ISN A;  2Q13 A;  1J0W A;  2DA0 A;  3HSA A;  1XD4 A;  3GYO A;  2Y7B A;  1EVH A;  3T06 A;  1XKE A;  3G9W A;  2D9Y A;  5DHF B;  2CY5 A;  2G35 A;  2N0Y A;  4Z2N A;  1LB1 A; 
#chains in the Genus database with same CATH homology
 3PVW A;  2GCJ A;  2D11 A;  1U5D A;  2Z0O A;  4HAU B;  1OQN A;  3KRW A;  1V89 A;  1SHC A;  1X05 A;  5CLQ B;  2YS5 A;  2W2X C;  2J0K A;  4GXB A;  4GPT B;  2D10 A;  1FHX A;  3DXD A;  3A8Q A;  5HE2 A;  5LOP B;  2I1J A;  1TJ6 A;  1W1D A;  4HDO A;  2YVC A;  3BIN A;  3HW2 B;  5DIF B;  2HTH B;  2NMB A;  2N23 A;  2K2U A;  2K00 A;  3U8Z A;  2GJY A;  2MDX A;  2P0H A;  2KUP A;  2COC A;  3SNH A;  5JP4 A;  3OAN A;  1IRS A;  4PQ0 A;  3FM8 C;  2H7E A;  3TVV A;  1SGH A;  4WVF B;  2RSG A;  1U2B A;  4H8S A;  4HAZ B;  3PVL A;  5DHA B;  5L81 A;  4DXA B;  4EKU A;  4PNK A;  1NTV A;  1M7R A;  2NZ8 B;  4C0A A;  5JHG A;  1XR0 B;  3AU4 A;  2JP2 A;  5HE1 A;  4A5K A;  2DYQ A;  4NSW A;  2COD A;  5DH9 B;  3P7Z A;  2EJ8 A;  4XWX A;  2K2J A;  2VSZ A;  2EC1 A;  1MIZ B;  4MK0 A;  2DN6 A;  3M1I B;  1X11 A;  1Z87 A;  5JHH A;  1N3H A;  1K5D B;  1GC6 A;  1V88 A;  3MDB C;  2YS1 A;  2RNR B;  1PLS A;  2QKL A;  3ODW A;  1MK9 B;  1WGQ A;  4KHO A;  4HAY B;  3O96 A;  3F5R A;  1E5W A;  4GN1 A;  1QQG A;  2LOX A;  4K17 A;  4YL8 A;  1WJ1 A;  1FHO A;  3ULC A;  1ZVR A;  4F7G A;  5D3X A;  2D4Q A;  1FGY A;  1TXD A;  1P3R A;  2VRW B;  4HAT B;  5D3W A;  4KVG B;  4MT7 A;  1DRO A;  1DDV A;  1BTN A;  3HK0 A;  3TCA A;  1BAK A;  1UPR A;  2OQB A;  4Y94 A;  2J0M A;  1I7A A;  2M38 A;  4CYE A;  1P6S A;  2DHJ A;  4HAX B;  5C5B B;  3DXC A;  1MKE A;  4A6K A;  2RGN B;  2IFS A;  5D3V A;  4CHJ A;  1QC6 A;  4DX9 0;  4F7H A;  2DHI A;  3PEG A;  1RJ2 A;  3TO1 A;  2W2W A;  3X23 A;  1UEF A;  2RVB B;  3ZVR A;  2DKQ A;  3KSY A;  2DLW A;  2J59 M;  1ZC4 B;  4A6F B;  5C79 A;  4A6H A;  4KHB B;  2CRF A;  5HE3 A;  3AU5 A;  1WJM A;  2I5F A;  1U5G A;  1I2H A;  4ZRK A;  2AEH A;  2EMS A;  4HAW B;  1KZ7 A;  4HB4 B;  4IFS A;  4HAV B;  1J19 A;  2ELB A;  1AQC A;  2DYN A;  1FB8 A;  1X1F A;  2OTX A;  5J3Y A;  2DHK A;  2R0D A;  2P8V A;  3WA0 A;  1V61 A;  2QKM A;  2ROV A;  3D8D A;  3UZT A;  2GS0 A;  2KGX B;  2FJL A;  2J0J A;  3ODO A;  3U7D A;  3A8P A;  3PG7 A;  3F0W A;  2ZPY A;  3SV1 A;  2ADZ A;  2RUK B;  4P7I A;  2MFQ A;  5LON B;  4KAX B;  1MAI A;  4HB2 B;  4NY0 A;  1X1G A;  1KZG A;  3PSC A;  5C6R A;  3PP2 A;  2KCJ A;  3SYX A;  1W1G A;  1TQZ A;  5J3T A;  2M14 A;  1UPQ A;  4GMV A;  1UNR A;  5J3Q A;  2UZR A;  1U5E A;  3RCP A;  4WSF A;  1FGZ A;  5KQ4 A;  1H4R A;  2W2X D;  5JLJ B;  4HB3 B;  2YT0 A;  1OY2 A;  1GG3 A;  1AWE A;  2X18 A;  2D9W A;  4EMO A;  4DX8 A;  3KZ1 A;  3P6A A;  4YON A;  3KY9 A;  3WYF B;  5D3Y A;  1EGX A;  2ELA A;  1NU2 A;  2GCL A;  1P5T A;  3VOQ A;  5GOW B;  3BJI A;  2YS3 A;  1BWN A;  1XCG A;  1FOE A;  4DBB A;  3KRX A;  1EAZ A;  4EJN A;  1GC7 A;  3D8F A;  1XX0 A;  2D9Z A;  2I1K A;  1FAO A;  4GMX B;  1Y5O A;  4KHA A;  1LW3 A;  5C5B A;  1WI1 A;  1NI2 A;  4ZRJ A;  1Y19 B;  1MK7 B;  1XOD A;  4Z2M B;  3SUZ A;  3LJU X;  2UZS A;  3HQC A;  4TKN A;  1W1H A;  3TW1 A;  3V5W A;  1BTK A;  2BCJ A;  4A6F A;  1MIX A;  4IAP A;  3N7C A;  2AL6 A;  4B6H A;  2Y8F A;  3ULB A;  1UNP A;  1V5U A;  3TFM A;  5EFX A;  3VIA A;  5KCV A;  2VKI A;  1KI1 B;  2Z0P A;  2P0F A;  4CHM A;  2YF0 A;  2COA A;  4IOY X;  3NSU A;  5FI0 A;  2PZ1 A;  3MPX A;  2V76 A;  2E2X A;  5D27 A;  4HDQ A;  2DFK A;  5CLL B;  2DX1 A;  2R09 A;  1DYN A;  3QBV B;  3CIK A;  3QWM A;  4K2O A;  4K81 A;  1OMW A;  3QIJ A;  2Z0Q A;  2D2Q A;  2LYD A;  2MKR A;  2RLO A;  1ZC3 B;  2DKP A;  1U29 A;  1Q67 A;  1UNQ A;  4GZU A;  2CAY A;  4L6E A;  4ZRI A;  1U27 A;  3ODX A;  2YSZ A;  5C16 A;  2MWN B;  5KQ1 A;  4HHV A;  1WVH A;  3ML4 A;  1V5M A;  3GYP A;  1H10 A;  1DDM A;  1DDW A;  5FI1 A;  2D9V A;  2YRY A;  2I5C A;  1RRP B;  2DX5 A;  2Y8G A;  1MPH A;  2LG1 A;  1U5F A;  3D8E A;  3DXE A;  1M7E A;  2LUL A;  4WJ7 A;  2LKO A;  3FSS A;  2ROZ B;  4F7U P;  3SO6 A;  2IYB A;  1V5P A;  1ZSQ A;  3CXB B;  1ZM0 A;  1PMS A;  3FEH A;  3AJ4 A;  1K5G B;  1WG7 A;  2DTC A;  3ZDT A;  1NTY A;  4BBK A;  4MY6 A;  2HE7 A;  4D0N B;  4HB0 B;  3PVU A;  2L1C A;  3A98 B;  1DBH A;  5HE0 A;  1FHW A;  5DI9 B;  2YT1 A;  2LOZ A;  2UVM A;  3PZD A;  2H7D A;  2EMT A;  2CY4 A;  4K2P A;  1WGU A;  2D9X A;  3IVF A;  1PFJ A;  2L2I A;  1B55 A;  2COF A;  1EF1 A;  1X86 A;  2P0D A;  2XQN M;  4TYZ A;  1ISN A;  2Q13 A;  1J0W A;  2DA0 A;  1XD4 A;  3GYO A;  2Y7B A;  1EVH A;  3T06 A;  1XKE A;  3G9W A;  2D9Y A;  5DHF B;  2CY5 A;  2G35 A;  2N0Y A;  4Z2N A;  1LB1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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