2K2UA

Nmr structure of the complex between tfb1 subunit of tfiih and the activation domain of vp16
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
115
structure length
115
Chain Sequence
PSHSGAAIFEKVSGIIAINEDVSPAELTWRSTDGDKVHTVVLSTIDKLQATPASSEKMMLRLIGKVDESKKRKDNEGNEVVPKPQRHMFSFNNRTVMDNIKMTLQQIISRYKDAD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR Structure of the Complex between the Tfb1 Subunit of TFIIH and the Activation Domain of VP16: Structural Similarities between VP16 and p53.
pubmed doi rcsb
molecule tags Transcription
source organism Saccharomyces cerevisiae
molecule keywords RNA polymerase II transcription factor B subunit 1
total genus 19
structure length 115
sequence length 115
ec nomenclature
pdb deposition date 2008-04-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08567 PH_TFIIH TFIIH p62 subunit, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 2k2uA00
2J0KA 3X23A 1P5TA 1RRPB 2FJLA 1X11A 3ULBA 4KHAA 2NMBA 2M38A 2P0FA 2RGNB 3NSUA 3WA0A 1E5WA 4MY6A 4XWXA 5C6RA 4HAYB 2CRFA 2Q13A 4PQ0A 3OANA 5C5BB 3ODWA 1MKEA 1FHWA 4MT7A 1RJ2A 3VIAA 2QKLA 2LG1A 2EMTA 4HB4B 3AJ4A 4A5KA 2MFQA 4GN1A 1MK7B 1W1HA 4K2OA 3D8EA 2QKMA 1V61A 1OMWA 4D0NB 3DXEA 2GCLA 1V89A 2ROZB 3HK0A 5C5BA 4B6HA 4A6FB 3KY9A 1WJMA 2DKQA 1SGHA 1FGYA 2ROVA 3QWMA 3BJIA 3AU4A 1UNQA 4K2PA 4EMOA 1P3RA 1U2BA 3U7DA 3ODXA 1TXDA 1DBHA 1K5DB 1Q67A 2YS5A 1DDMA 1UPQA 2LULA 2KCJA 3ODOA 2CODA 1W1GA 1X1FA 4TKNA 3TCAA 4CHJA 1PFJA 4EJNA 1WGQA 2DTCA 5D27A 5D3YA 1I7AA 2K00A 4IAPA 2COCA 2GS0A 3PP2A 4HAVB 1FHOA 1N3HA 2LOXA 1GC6A 1ZC4B 2D11A 3UZTA 3FSSA 2I5FA 1LW3A 2YT1A 2DFKA 2H7DA 3SUZA 1TJ6A 1WI1A 2J59M 2UZRA 4HATB 1WJ1A 3PVUA 3TVVA 3P7ZA 2DX5A 2HTHB 4CYEA 3GYOA 1EGXA 1XODA 3FM8C 4F7UP 1BTKA 2CAYA 3CIKA 2MWNB 1H10A 2N23A 2CY4A 2GJYA 2PZ1A 3SV1A 4GPTB 1XX0A 2YRYA 4DXAB 4HHVA 3DXDA 1FHXA 1ZVRA 4ZRKA 5FI0A 4A6HA 5KCVA 1AWEA 1AQCA 1QC6A 1J19A 1SHCA 1Y19B 2E2XA 5D3XA 5DH9B 2H7EA 1MIZB 5HE2A 3VOQA 2RNRB 3TO1A 1KZGA 4KAXB 2EMSA 3HW2B 2I5CA 5CLQB 3A8PA 4WVFB 5D3VA 3G9WA 2KUPA 5J3QA 2VRWB 3MPXA 1BTNA 2P0DA 2J0JA 2DYQA 1V5UA 2HE7A 3WYFB 1UNPA 1V88A 2GCJA 2LYDA 3FEHA 1U29A 4K17A 4Y94A 3P6AA 2D10A 1WG7A 1XCGA 2EJ8A 1QQGA 1LB1A 2YSZA 3M1IB 3MDBC 1ZC3B 4F7HA 2D9ZA 2RSGA 1XR0B 2KGXB 1U5FA 1X1GA 3V5WA 4HAUB 2YVCA 3SNHA 4HDQA 1UNRA 2MKRA 3PVWA 5KQ4A 1KZ7A 4GMXB 4GXBA 2YS3A 4HAXB 4CHMA 1DDWA 2JP2A 3T06A 5GOWB 1NI2A 3PVLA 1H4RA 4F7GA 3ULCA 1PMSA 1TQZA 2R09A 2Z0OA 1FB8A 4YL8A 5D3WA 3BINA 2EC1A 5LONB 1ISNA 4EKUA 3LJUX 1U5DA 2IYBA 2K2UA 5C16A 2DKPA 1B55A 1FAOA 3QBVB 1UEFA 4HB2B 5DHAB 5KQ1A 4ZRIA 4KHBB 4P7IA 2UZSA 5HE0A 2XQNM 1XKEA 4HAWB 2ELAA 4NSWA 2MDXA 3N7CA 1Z87A 3O96A 2DX1A 4KHOA 2COFA 2YF0A 2DLWA 1WGUA 2I1KA 4HB0B 4WSFA 1X86A 5HE3A 2X18A 1V5MA 2W2XD 5JHGA 1MIXA 3PSCA 5LOPB 2P0HA 2LKOA 3ML4A 3DXCA 4IFSA 4TYZA 1K5GB 4DX90 2D4QA 1MAIA 4Z2MB 3PEGA 3AU5A 3PG7A 5FI1A 1X05A 2N0YA 2L1CA 4MK0A 1M7EA 3IVFA 3ZVRA 2W2XC 3F5RA 3KRXA 1MPHA 2COAA 3SO6A 1J0WA 2L2IA 4Z2NA 3U8ZA 4DBBA 2RUKB 1U5GA 2DHJA 2LOZA 2DN6A 2DHIA 3HQCA 5DIFB 1FGZA 4DX8A 1UPRA 4H8SA 2RLOA 1U5EA 1WVHA 2Z0PA 4IOYX 2VKIA 1KI1B 1FOEA 2RVBB 3SYXA 3RCPA 3A8QA 3KZ1A 2AL6A 4A6KA 2G35A 4C0AA 2ZPYA 5CLLB 5HE1A 2DYNA 5JHHA 2M14A 3QIJA 1PLSA 1ZM0A 2D2QA 4BBKA 2YS1A 5DI9B 2DA0A 1EF1A 1DYNA 3CXBB 1P6SA 4A6FA 2Y8FA 3KRWA 1IRSA 5EFXA 1BWNA 1XD4A 2DHKA 2UVMA 3D8FA 1EAZA 5J3TA 2D9WA 2Z0QA 4K81A 3GYPA 5L81A 4HDOA 1DROA 2V76A 2ADZA 3KSYA 4GMVA 5DHFB 1OQNA 1MK9B 1NTVA 4ZRJA 5JLJB 1GG3A 2R0DA 4YONA 4KVGB 5JP4A 2W2WA 1M7RA 2J0MA 3PZDA 3F0WA 1NTYA 2AEHA 2Y8GA 4WJ7A 2I1JA 2VSZA 2YT0A 4HB3B 2OTXA 3TW1A 1ZSQA 2ELBA 1BAKA 2D9VA 1Y5OA 2D9YA 1EVHA 4HAZB 1I2HA 2BCJA 2NZ8B 2OQBA 1V5PA 4PNKA 3TFMA 1W1DA 5J3YA 2Y7BA 1OY2A 1NU2A 4L6EA 4NY0A 4GZUA 2D9XA 3D8DA 2CY5A 2P8VA 3A98B 2IFSA 1GC7A 5C79A 2K2JA 1U27A 3ZDTA 1DDVA
chains in the Genus database with same CATH superfamily
2J0KA 2K49A 3X23A 1P5TA 1RRPB 2FJLA 1X11A 1T77A 3ULBA 4KHAA 2NMBA 2M38A 2P0FA 2RGNB 3NSUA 3WA0A 1E5WA 4MY6A 4XWXA 4QXAB 5C6RA 4HAYB 2CRFA 2Q13A 4PQ0A 3OANA 5C5BB 3ODWA 1MKEA 4GNKB 1FHWA 1ZYIA 3NWFA 4MT7A 1RJ2A 3VIAA 2QKLA 2LG1A 2EMTA 4HB4B 3AJ4A 4A5KA 2MFQA 4GN1A 1MK7B 1W1HA 4K2OA 3D8EA 2Z13A 2QKMA 1V61A 1OMWA 4D0NB 3DXEA 2GCLA 1V89A 2ROZB 3HK0A 5C5BA 4B6HA 4A6FB 3KY9A 1WJMA 2DKQA 1SGHA 1FGYA 2ROVA 4CSQA 3QWMA 3BJIA 3AU4A 1UNQA 4K2PA 4EMOA 1P3RA 2FJUB 1U2BA 3U7DA 3ODXA 1TXDA 1DBHA 1K5DB 1Q67A 2YS5A 1DDMA 1UPQA 2LULA 2KCJA 3ODOA 2CODA 1W1GA 1X1FA 4TKNA 3TCAA 4CHJA 1PFJA 2KIGA 4EJNA 2KUQA 4DIXA 1WGQA 2DTCA 2YT2A 5D27A 5D3YA 1I7AA 2K00A 4IAPA 2COCA 2GS0A 3PP2A 4HAVB 2KR0A 1FHOA 1N3HA 2LOXA 4L1RA 1GC6A 1ZC4B 2D11A 3DCXA 3UZTA 3FSSA 2I5FA 1LW3A 2YT1A 2DFKA 2H7DA 3SUZA 1TJ6A 1WI1A 2J59M 2UZRA 4HATB 1WJ1A 3PVUA 2K8EA 3TVVA 3P7ZA 2DX5A 2HTHB 4CYEA 3GYOA 1EGXA 1XODA 2Z14A 3FM8C 4F7UP 4GOUA 1BTKA 2CAYA 3CIKA 2MWNB 1H10A 2N23A 2CY4A 2GJYA 2PZ1A 3SV1A 4GPTB 2Z59A 1XX0A 2YRYA 4DXAB 4HHVA 3DXDA 1FHXA 4KHBA 1ZVRA 4ZRKA 5FI0A 4A6HA 5KCVA 1AWEA 1AQCA 2GUMA 1QC6A 1J19A 1SHCA 1Y19B 2E2XA 5D3XA 5I2MA 5DH9B 2H7EA 1MIZB 4QJ5B 4HSIA 5HE2A 3VOQA 2RNRB 4QJ3B 3TO1A 1KZGA 4KAXB 4OSNA 2EMSA 3HW2B 2I5CA 5CLQB 3A8PA 4WVFB 5D3VA 3G9WA 2KUPA 5J3QA 2VRWB 3MPXA 1BTNA 2P0DA 2J0JA 2DYQA 1V5UA 2HE7A 3WYFB 1UNPA 1V88A 2GCJA 2LYDA 3FEHA 1U29A 4K17A 4Y94A 3P6AA 2D10A 1WG7A 1XCGA 2EJ8A 1QQGA 1LB1A 2YSZA 3M1IB 3MDBC 1ZC3B 5I2SA 4F7HA 2D9ZA 2RSGA 1XR0B 2KGXB 1U5FA 1X1GA 3U12A 3V5WA 4HAUB 2YVCA 3SNHA 4HDQA 1UNRA 2MKRA 3PVWA 5KQ4A 1KZ7A 4GMXB 4GXBA 2YS3A 4HAXB 4CHMA 1DDWA 4D6WA 2JP2A 2RRFA 3T06A 5GOWB 1NI2A 3PVLA 1H4RA 4F7GA 3ULCA 1PMSA 1TQZA 4OT1A 2R09A 2Z0OA 1FB8A 4YL8A 5D3WA 3BINA 2EC1A 5LONB 1ISNA 4EKUA 3LJUX 1U5DA 2IYBA 2K2UA 3FVCA 5C16A 2DKPA 1B55A 1FAOA 3QBVB 1UEFA 3B77A 3NWAA 4HB2B 5DHAB 2KIEA 5KQ1A 2NBVA 4ZRIA 4KHBB 4P7IA 2UZSA 5HE0A 2XQNM 1XKEA 4HAWB 2ELAA 4NSWA 2MDXA 3N7CA 1Z87A 3O96A 2DX1A 4KHOA 2COFA 2YF0A 2DLWA 1WGUA 2I1KA 4HB0B 4WSFA 1X86A 5HE3A 2X18A 1V5MA 2W2XD 3NW8A 5JHGA 1MIXA 3PSCA 5LOPB 2P0HA 2LKOA 3ML4A 3DXCA 4IFSA 4TYZA 1K5GB 4DX90 2D4QA 1MAIA 4Z2MB 3PEGA 5M4YB 3AU5A 3PG7A 5FI1A 1X05A 2N0YA 2L1CA 4MK0A 1M7EA 3IVFA 2Z4DA 3ZVRA 2W2XC 3F5RA 3KRXA 1MPHA 2COAA 3A58A 3SO6A 1J0WA 2L2IA 4Z2NA 3U8ZA 4DBBA 2RUKB 1U5GA 2DHJA 2LOZA 2DN6A 2DHIA 3HQCA 5DIFB 1FGZA 4DX8A 1UPRA 4H8SA 2RLOA 1U5EA 1WVHA 2Z0PA 4IOYX 2VKIA 1KI1B 1FOEA 3NWDA 2RVBB 3SYXA 3RCPA 3A8QA 3KZ1A 2AL6A 3HIEA 2G35A 4A6KA 4C0AA 2ZPYA 5CLLB 5HE1A 3OHMB 2DYNA 5JHHA 2M14A 3QIJA 1PLSA 5LG4B 1ZM0A 2ZKMX 2D2QA 4BBKA 4QJ4B 2YS1A 1MI1A 2DA0A 5DI9B 1EF1A 3HSAA 1DYNA 3CXBB 1P6SA 4A6FA 2Y8FA 3KRWA 1IRSA 5EFXA 1BWNA 1XD4A 2DHKA 2UVMA 3D8FA 1EAZA 5J3TA 2D9WA 2Z0QA 4K81A 3GYPA 5L81A 4HDOA 1DROA 2V76A 2ADZA 3KSYA 4GMVA 5DHFB 1OQNA 1MK9B 1NTVA 4ZRJA 5JLJB 1GG3A 2R0DA 4YONA 4KVGB 5JP4A 2W2WA 1M7RA 2J0MA 3PZDA 3F0WA 1NTYA 2AEHA 2Y8GA 4WJ7A 2I1JA 2VSZA 2YT0A 4HB3B 2OTXA 3TW1A 1ZSQA 2ELBA 1BAKA 2D9VA 1Y5OA 2D9YA 1EVHA 4HAZB 1I2HA 2BCJA 2NZ8B 2OQBA 1V5PA 4PNKA 3TFMA 1W1DA 5J3YA 2Y7BA 1OY2A 5IRSA 1NU2A 4L6EA 4NY0A 4GZUA 2R2YA 2D9XA 3D8DA 2CY5A 2P8VA 3A98B 2IFSA 1GC7A 5C79A 2K2JA 1U27A 3ZDTA 1DDVA
chains in the Genus database with same CATH topology
2J0KA 3X23A 1P5TA 1RRPB 2FJLA 1X11A 3ULBA 4KHAA 2NMBA 2M38A 2P0FA 2RGNB 3NSUA 3WA0A 1E5WA 4MY6A 4XWXA 5C6RA 4HAYB 2CRFA 2Q13A 4PQ0A 3OANA 5C5BB 3ODWA 1MKEA 1FHWA 4MT7A 1RJ2A 3VIAA 2QKLA 2LG1A 2EMTA 4HB4B 3AJ4A 4A5KA 2MFQA 4GN1A 1MK7B 1W1HA 4K2OA 3D8EA 2QKMA 1V61A 1OMWA 4D0NB 3DXEA 2GCLA 1V89A 2ROZB 3HK0A 5C5BA 4B6HA 4A6FB 3KY9A 1WJMA 2DKQA 1SGHA 1FGYA 2ROVA 3QWMA 3BJIA 3AU4A 1UNQA 4K2PA 4EMOA 1P3RA 1U2BA 3U7DA 3ODXA 1TXDA 1DBHA 1K5DB 1Q67A 2YS5A 1DDMA 1UPQA 2LULA 2KCJA 3ODOA 2CODA 1W1GA 1X1FA 4TKNA 3TCAA 4CHJA 1PFJA 4EJNA 1WGQA 2DTCA 5D27A 5D3YA 1I7AA 2K00A 4IAPA 2COCA 2GS0A 3PP2A 4HAVB 1FHOA 1N3HA 2LOXA 1GC6A 1ZC4B 2D11A 3UZTA 3FSSA 2I5FA 1LW3A 2YT1A 2DFKA 2H7DA 3SUZA 1TJ6A 1WI1A 2J59M 2UZRA 4HATB 1WJ1A 3PVUA 3TVVA 3P7ZA 2DX5A 2HTHB 4CYEA 3GYOA 1EGXA 1XODA 3FM8C 4F7UP 1BTKA 2CAYA 3CIKA 2MWNB 1H10A 2N23A 2CY4A 2GJYA 2PZ1A 3SV1A 4GPTB 1XX0A 2YRYA 4DXAB 4HHVA 3DXDA 1FHXA 1ZVRA 4ZRKA 5FI0A 4A6HA 5KCVA 1AWEA 1AQCA 1QC6A 1J19A 1SHCA 1Y19B 2E2XA 5D3XA 5DH9B 2H7EA 1MIZB 5HE2A 3VOQA 2RNRB 3TO1A 1KZGA 4KAXB 2EMSA 3HW2B 2I5CA 5CLQB 3A8PA 4WVFB 5D3VA 3G9WA 2KUPA 5J3QA 2VRWB 3MPXA 1BTNA 2P0DA 2J0JA 2DYQA 1V5UA 2HE7A 3WYFB 1UNPA 1V88A 2GCJA 2LYDA 3FEHA 1U29A 4K17A 4Y94A 3P6AA 2D10A 1WG7A 1XCGA 2EJ8A 1QQGA 1LB1A 2YSZA 3M1IB 3MDBC 1ZC3B 4F7HA 2D9ZA 2RSGA 1XR0B 2KGXB 1U5FA 1X1GA 3V5WA 4HAUB 2YVCA 3SNHA 4HDQA 1UNRA 2MKRA 3PVWA 5KQ4A 1KZ7A 4GMXB 4GXBA 2YS3A 4HAXB 4CHMA 1DDWA 2JP2A 3T06A 5GOWB 1NI2A 3PVLA 1H4RA 4F7GA 3ULCA 1PMSA 1TQZA 2R09A 2Z0OA 1FB8A 4YL8A 5D3WA 3BINA 2EC1A 5LONB 1ISNA 4EKUA 3LJUX 1U5DA 2IYBA 2K2UA 5C16A 2DKPA 1B55A 1FAOA 3QBVB 1UEFA 4HB2B 5DHAB 5KQ1A 4ZRIA 4KHBB 4P7IA 2UZSA 5HE0A 2XQNM 1XKEA 4HAWB 2ELAA 4NSWA 2MDXA 3N7CA 1Z87A 3O96A 2DX1A 4KHOA 2COFA 2YF0A 2DLWA 1WGUA 2I1KA 4HB0B 4WSFA 1X86A 5HE3A 2X18A 1V5MA 2W2XD 5JHGA 1MIXA 3PSCA 5LOPB 2P0HA 2LKOA 3ML4A 3DXCA 4IFSA 4TYZA 1K5GB 4DX90 2D4QA 1MAIA 4Z2MB 3PEGA 3AU5A 3PG7A 5FI1A 1X05A 2N0YA 2L1CA 4MK0A 1M7EA 3IVFA 3ZVRA 2W2XC 3F5RA 3KRXA 1MPHA 2COAA 3SO6A 1J0WA 2L2IA 4Z2NA 3U8ZA 4DBBA 2RUKB 1U5GA 2DHJA 2LOZA 2DN6A 2DHIA 3HQCA 5DIFB 1FGZA 4DX8A 1UPRA 4H8SA 2RLOA 1U5EA 1WVHA 2Z0PA 4IOYX 2VKIA 1KI1B 1FOEA 2RVBB 3SYXA 3RCPA 3A8QA 3KZ1A 2AL6A 4A6KA 2G35A 4C0AA 2ZPYA 5CLLB 5HE1A 2DYNA 5JHHA 2M14A 3QIJA 1PLSA 1ZM0A 2D2QA 4BBKA 2YS1A 5DI9B 2DA0A 1EF1A 1DYNA 3CXBB 1P6SA 4A6FA 2Y8FA 3KRWA 1IRSA 5EFXA 1BWNA 1XD4A 2DHKA 2UVMA 3D8FA 1EAZA 5J3TA 2D9WA 2Z0QA 4K81A 3GYPA 5L81A 4HDOA 1DROA 2V76A 2ADZA 3KSYA 4GMVA 5DHFB 1OQNA 1MK9B 1NTVA 4ZRJA 5JLJB 1GG3A 2R0DA 4YONA 4KVGB 5JP4A 2W2WA 1M7RA 2J0MA 3PZDA 3F0WA 1NTYA 2AEHA 2Y8GA 4WJ7A 2I1JA 2VSZA 2YT0A 4HB3B 2OTXA 3TW1A 1ZSQA 2ELBA 1BAKA 2D9VA 1Y5OA 2D9YA 1EVHA 4HAZB 1I2HA 2BCJA 2NZ8B 2OQBA 1V5PA 4PNKA 3TFMA 1W1DA 5J3YA 2Y7BA 1OY2A 1NU2A 4L6EA 4NY0A 4GZUA 2D9XA 3D8DA 2CY5A 2P8VA 3A98B 2IFSA 1GC7A 5C79A 2K2JA 1U27A 3ZDTA 1DDVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J0K A;  3X23 A;  1P5T A;  1RRP B;  2FJL A;  1X11 A;  3ULB A;  4KHA A;  2NMB A;  2M38 A;  2P0F A;  2RGN B;  3NSU A;  3WA0 A;  1E5W A;  4MY6 A;  4XWX A;  5C6R A;  4HAY B;  2CRF A;  2Q13 A;  4PQ0 A;  3OAN A;  5C5B B;  3ODW A;  1MKE A;  1FHW A;  4MT7 A;  1RJ2 A;  3VIA A;  2QKL A;  2LG1 A;  2EMT A;  4HB4 B;  3AJ4 A;  4A5K A;  2MFQ A;  4GN1 A;  1MK7 B;  1W1H A;  4K2O A;  3D8E A;  2QKM A;  1V61 A;  1OMW A;  4D0N B;  3DXE A;  2GCL A;  1V89 A;  2ROZ B;  3HK0 A;  5C5B A;  4B6H A;  4A6F B;  3KY9 A;  1WJM A;  2DKQ A;  1SGH A;  1FGY A;  2ROV A;  3QWM A;  3BJI A;  3AU4 A;  1UNQ A;  4K2P A;  4EMO A;  1P3R A;  1U2B A;  3U7D A;  3ODX A;  1TXD A;  1DBH A;  1K5D B;  1Q67 A;  2YS5 A;  1DDM A;  1UPQ A;  2LUL A;  2KCJ A;  3ODO A;  2COD A;  1W1G A;  1X1F A;  4TKN A;  3TCA A;  4CHJ A;  1PFJ A;  4EJN A;  1WGQ A;  2DTC A;  5D27 A;  5D3Y A;  1I7A A;  2K00 A;  4IAP A;  2COC A;  2GS0 A;  3PP2 A;  4HAV B;  1FHO A;  1N3H A;  2LOX A;  1GC6 A;  1ZC4 B;  2D11 A;  3UZT A;  3FSS A;  2I5F A;  1LW3 A;  2YT1 A;  2DFK A;  2H7D A;  3SUZ A;  1TJ6 A;  1WI1 A;  2J59 M;  2UZR A;  4HAT B;  1WJ1 A;  3PVU A;  3TVV A;  3P7Z A;  2DX5 A;  2HTH B;  4CYE A;  3GYO A;  1EGX A;  1XOD A;  3FM8 C;  4F7U P;  1BTK A;  2CAY A;  3CIK A;  2MWN B;  1H10 A;  2N23 A;  2CY4 A;  2GJY A;  2PZ1 A;  3SV1 A;  4GPT B;  1XX0 A;  2YRY A;  4DXA B;  4HHV A;  3DXD A;  1FHX A;  1ZVR A;  4ZRK A;  5FI0 A;  4A6H A;  5KCV A;  1AWE A;  1AQC A;  1QC6 A;  1J19 A;  1SHC A;  1Y19 B;  2E2X A;  5D3X A;  5DH9 B;  2H7E A;  1MIZ B;  5HE2 A;  3VOQ A;  2RNR B;  3TO1 A;  1KZG A;  4KAX B;  2EMS A;  3HW2 B;  2I5C A;  5CLQ B;  3A8P A;  4WVF B;  5D3V A;  3G9W A;  2KUP A;  5J3Q A;  2VRW B;  3MPX A;  1BTN A;  2P0D A;  2J0J A;  2DYQ A;  1V5U A;  2HE7 A;  3WYF B;  1UNP A;  1V88 A;  2GCJ A;  2LYD A;  3FEH A;  1U29 A;  4K17 A;  4Y94 A;  3P6A A;  2D10 A;  1WG7 A;  1XCG A;  2EJ8 A;  1QQG A;  1LB1 A;  2YSZ A;  3M1I B;  3MDB C;  1ZC3 B;  4F7H A;  2D9Z A;  2RSG A;  1XR0 B;  2KGX B;  1U5F A;  1X1G A;  3V5W A;  4HAU B;  2YVC A;  3SNH A;  4HDQ A;  1UNR A;  2MKR A;  3PVW A;  5KQ4 A;  1KZ7 A;  4GMX B;  4GXB A;  2YS3 A;  4HAX B;  4CHM A;  1DDW A;  2JP2 A;  3T06 A;  5GOW B;  1NI2 A;  3PVL A;  1H4R A;  4F7G A;  3ULC A;  1PMS A;  1TQZ A;  2R09 A;  2Z0O A;  1FB8 A;  4YL8 A;  5D3W A;  3BIN A;  2EC1 A;  5LON B;  1ISN A;  4EKU A;  3LJU X;  1U5D A;  2IYB A;  2K2U A;  5C16 A;  2DKP A;  1B55 A;  1FAO A;  3QBV B;  1UEF A;  4HB2 B;  5DHA B;  5KQ1 A;  4ZRI A;  4KHB B;  4P7I A;  2UZS A;  5HE0 A;  2XQN M;  1XKE A;  4HAW B;  2ELA A;  4NSW A;  2MDX A;  3N7C A;  1Z87 A;  3O96 A;  2DX1 A;  4KHO A;  2COF A;  2YF0 A;  2DLW A;  1WGU A;  2I1K A;  4HB0 B;  4WSF A;  1X86 A;  5HE3 A;  2X18 A;  1V5M A;  2W2X D;  5JHG A;  1MIX A;  3PSC A;  5LOP B;  2P0H A;  2LKO A;  3ML4 A;  3DXC A;  4IFS A;  4TYZ A;  1K5G B;  4DX9 0;  2D4Q A;  1MAI A;  4Z2M B;  3PEG A;  3AU5 A;  3PG7 A;  5FI1 A;  1X05 A;  2N0Y A;  2L1C A;  4MK0 A;  1M7E A;  3IVF A;  3ZVR A;  2W2X C;  3F5R A;  3KRX A;  1MPH A;  2COA A;  3SO6 A;  1J0W A;  2L2I A;  4Z2N A;  3U8Z A;  4DBB A;  2RUK B;  1U5G A;  2DHJ A;  2LOZ A;  2DN6 A;  2DHI A;  3HQC A;  5DIF B;  1FGZ A;  4DX8 A;  1UPR A;  4H8S A;  2RLO A;  1U5E A;  1WVH A;  2Z0P A;  4IOY X;  2VKI A;  1KI1 B;  1FOE A;  2RVB B;  3SYX A;  3RCP A;  3A8Q A;  3KZ1 A;  2AL6 A;  4A6K A;  2G35 A;  4C0A A;  2ZPY A;  5CLL B;  5HE1 A;  2DYN A;  5JHH A;  2M14 A;  3QIJ A;  1PLS A;  1ZM0 A;  2D2Q A;  4BBK A;  2YS1 A;  5DI9 B;  2DA0 A;  1EF1 A;  1DYN A;  3CXB B;  1P6S A;  4A6F A;  2Y8F A;  3KRW A;  1IRS A;  5EFX A;  1BWN A;  1XD4 A;  2DHK A;  2UVM A;  3D8F A;  1EAZ A;  5J3T A;  2D9W A;  2Z0Q A;  4K81 A;  3GYP A;  5L81 A;  4HDO A;  1DRO A;  2V76 A;  2ADZ A;  3KSY A;  4GMV A;  5DHF B;  1OQN A;  1MK9 B;  1NTV A;  4ZRJ A;  5JLJ B;  1GG3 A;  2R0D A;  4YON A;  4KVG B;  5JP4 A;  2W2W A;  1M7R A;  2J0M A;  3PZD A;  3F0W A;  1NTY A;  2AEH A;  2Y8G A;  4WJ7 A;  2I1J A;  2VSZ A;  2YT0 A;  4HB3 B;  2OTX A;  3TW1 A;  1ZSQ A;  2ELB A;  1BAK A;  2D9V A;  1Y5O A;  2D9Y A;  1EVH A;  4HAZ B;  1I2H A;  2BCJ A;  2NZ8 B;  2OQB A;  1V5P A;  4PNK A;  3TFM A;  1W1D A;  5J3Y A;  2Y7B A;  1OY2 A;  1NU2 A;  4L6E A;  4NY0 A;  4GZU A;  2D9X A;  3D8D A;  2CY5 A;  2P8V A;  3A98 B;  2IFS A;  1GC7 A;  5C79 A;  2K2J A;  1U27 A;  3ZDT A;  1DDV A; 
#chains in the Genus database with same CATH topology
 2J0K A;  2K49 A;  3X23 A;  1P5T A;  1RRP B;  2FJL A;  1X11 A;  1T77 A;  3ULB A;  4KHA A;  2NMB A;  2M38 A;  2P0F A;  2RGN B;  3NSU A;  3WA0 A;  1E5W A;  4MY6 A;  4XWX A;  4QXA B;  5C6R A;  4HAY B;  2CRF A;  2Q13 A;  4PQ0 A;  3OAN A;  5C5B B;  3ODW A;  1MKE A;  4GNK B;  1FHW A;  1ZYI A;  3NWF A;  4MT7 A;  1RJ2 A;  3VIA A;  2QKL A;  2LG1 A;  2EMT A;  4HB4 B;  3AJ4 A;  4A5K A;  2MFQ A;  4GN1 A;  1MK7 B;  1W1H A;  4K2O A;  3D8E A;  2Z13 A;  2QKM A;  1V61 A;  1OMW A;  4D0N B;  3DXE A;  2GCL A;  1V89 A;  2ROZ B;  3HK0 A;  5C5B A;  4B6H A;  4A6F B;  3KY9 A;  1WJM A;  2DKQ A;  1SGH A;  1FGY A;  2ROV A;  4CSQ A;  3QWM A;  3BJI A;  3AU4 A;  1UNQ A;  4K2P A;  4EMO A;  1P3R A;  2FJU B;  1U2B A;  3U7D A;  3ODX A;  1TXD A;  1DBH A;  1K5D B;  1Q67 A;  2YS5 A;  1DDM A;  1UPQ A;  2LUL A;  2KCJ A;  3ODO A;  2COD A;  1W1G A;  1X1F A;  4TKN A;  3TCA A;  4CHJ A;  1PFJ A;  2KIG A;  4EJN A;  2KUQ A;  4DIX A;  1WGQ A;  2DTC A;  2YT2 A;  5D27 A;  5D3Y A;  1I7A A;  2K00 A;  4IAP A;  2COC A;  2GS0 A;  3PP2 A;  4HAV B;  2KR0 A;  1FHO A;  1N3H A;  2LOX A;  4L1R A;  1GC6 A;  1ZC4 B;  2D11 A;  3DCX A;  3UZT A;  3FSS A;  2I5F A;  1LW3 A;  2YT1 A;  2DFK A;  2H7D A;  3SUZ A;  1TJ6 A;  1WI1 A;  2J59 M;  2UZR A;  4HAT B;  1WJ1 A;  3PVU A;  2K8E A;  3TVV A;  3P7Z A;  2DX5 A;  2HTH B;  4CYE A;  3GYO A;  1EGX A;  1XOD A;  2Z14 A;  3FM8 C;  4F7U P;  4GOU A;  1BTK A;  2CAY A;  3CIK A;  2MWN B;  1H10 A;  2N23 A;  2CY4 A;  2GJY A;  2PZ1 A;  3SV1 A;  4GPT B;  2Z59 A;  1XX0 A;  2YRY A;  4DXA B;  4HHV A;  3DXD A;  1FHX A;  4KHB A;  1ZVR A;  4ZRK A;  5FI0 A;  4A6H A;  5KCV A;  1AWE A;  1AQC A;  2GUM A;  1QC6 A;  1J19 A;  1SHC A;  1Y19 B;  2E2X A;  5D3X A;  5I2M A;  5DH9 B;  2H7E A;  1MIZ B;  4QJ5 B;  4HSI A;  5HE2 A;  3VOQ A;  2RNR B;  4QJ3 B;  3TO1 A;  1KZG A;  4KAX B;  4OSN A;  2EMS A;  3HW2 B;  2I5C A;  5CLQ B;  3A8P A;  4WVF B;  5D3V A;  3G9W A;  2KUP A;  5J3Q A;  2VRW B;  3MPX A;  1BTN A;  2P0D A;  2J0J A;  2DYQ A;  1V5U A;  2HE7 A;  3WYF B;  1UNP A;  1V88 A;  2GCJ A;  2LYD A;  3FEH A;  1U29 A;  4K17 A;  4Y94 A;  3P6A A;  2D10 A;  1WG7 A;  1XCG A;  2EJ8 A;  1QQG A;  1LB1 A;  2YSZ A;  3M1I B;  3MDB C;  1ZC3 B;  5I2S A;  4F7H A;  2D9Z A;  2RSG A;  1XR0 B;  2KGX B;  1U5F A;  1X1G A;  3U12 A;  3V5W A;  4HAU B;  2YVC A;  3SNH A;  4HDQ A;  1UNR A;  2MKR A;  3PVW A;  5KQ4 A;  1KZ7 A;  4GMX B;  4GXB A;  2YS3 A;  4HAX B;  4CHM A;  1DDW A;  4D6W A;  2JP2 A;  2RRF A;  3T06 A;  5GOW B;  1NI2 A;  3PVL A;  1H4R A;  4F7G A;  3ULC A;  1PMS A;  1TQZ A;  4OT1 A;  2R09 A;  2Z0O A;  1FB8 A;  4YL8 A;  5D3W A;  3BIN A;  2EC1 A;  5LON B;  1ISN A;  4EKU A;  3LJU X;  1U5D A;  2IYB A;  2K2U A;  3FVC A;  5C16 A;  2DKP A;  1B55 A;  1FAO A;  3QBV B;  1UEF A;  3B77 A;  3NWA A;  4HB2 B;  5DHA B;  2KIE A;  5KQ1 A;  2NBV A;  4ZRI A;  4KHB B;  4P7I A;  2UZS A;  5HE0 A;  2XQN M;  1XKE A;  4HAW B;  2ELA A;  4NSW A;  2MDX A;  3N7C A;  1Z87 A;  3O96 A;  2DX1 A;  4KHO A;  2COF A;  2YF0 A;  2DLW A;  1WGU A;  2I1K A;  4HB0 B;  4WSF A;  1X86 A;  5HE3 A;  2X18 A;  1V5M A;  2W2X D;  3NW8 A;  5JHG A;  1MIX A;  3PSC A;  5LOP B;  2P0H A;  2LKO A;  3ML4 A;  3DXC A;  4IFS A;  4TYZ A;  1K5G B;  4DX9 0;  2D4Q A;  1MAI A;  4Z2M B;  3PEG A;  5M4Y B;  3AU5 A;  3PG7 A;  5FI1 A;  1X05 A;  2N0Y A;  2L1C A;  4MK0 A;  1M7E A;  3IVF A;  2Z4D A;  3ZVR A;  2W2X C;  3F5R A;  3KRX A;  1MPH A;  2COA A;  3A58 A;  3SO6 A;  1J0W A;  2L2I A;  4Z2N A;  3U8Z A;  4DBB A;  2RUK B;  1U5G A;  2DHJ A;  2LOZ A;  2DN6 A;  2DHI A;  3HQC A;  5DIF B;  1FGZ A;  4DX8 A;  1UPR A;  4H8S A;  2RLO A;  1U5E A;  1WVH A;  2Z0P A;  4IOY X;  2VKI A;  1KI1 B;  1FOE A;  3NWD A;  2RVB B;  3SYX A;  3RCP A;  3A8Q A;  3KZ1 A;  2AL6 A;  3HIE A;  2G35 A;  4A6K A;  4C0A A;  2ZPY A;  5CLL B;  5HE1 A;  3OHM B;  2DYN A;  5JHH A;  2M14 A;  3QIJ A;  1PLS A;  5LG4 B;  1ZM0 A;  2ZKM X;  2D2Q A;  4BBK A;  4QJ4 B;  2YS1 A;  1MI1 A;  2DA0 A;  5DI9 B;  1EF1 A;  3HSA A;  1DYN A;  3CXB B;  1P6S A;  4A6F A;  2Y8F A;  3KRW A;  1IRS A;  5EFX A;  1BWN A;  1XD4 A;  2DHK A;  2UVM A;  3D8F A;  1EAZ A;  5J3T A;  2D9W A;  2Z0Q A;  4K81 A;  3GYP A;  5L81 A;  4HDO A;  1DRO A;  2V76 A;  2ADZ A;  3KSY A;  4GMV A;  5DHF B;  1OQN A;  1MK9 B;  1NTV A;  4ZRJ A;  5JLJ B;  1GG3 A;  2R0D A;  4YON A;  4KVG B;  5JP4 A;  2W2W A;  1M7R A;  2J0M A;  3PZD A;  3F0W A;  1NTY A;  2AEH A;  2Y8G A;  4WJ7 A;  2I1J A;  2VSZ A;  2YT0 A;  4HB3 B;  2OTX A;  3TW1 A;  1ZSQ A;  2ELB A;  1BAK A;  2D9V A;  1Y5O A;  2D9Y A;  1EVH A;  4HAZ B;  1I2H A;  2BCJ A;  2NZ8 B;  2OQB A;  1V5P A;  4PNK A;  3TFM A;  1W1D A;  5J3Y A;  2Y7B A;  1OY2 A;  5IRS A;  1NU2 A;  4L6E A;  4NY0 A;  4GZU A;  2R2Y A;  2D9X A;  3D8D A;  2CY5 A;  2P8V A;  3A98 B;  2IFS A;  1GC7 A;  5C79 A;  2K2J A;  1U27 A;  3ZDT A;  1DDV A; 
#chains in the Genus database with same CATH homology
 2J0K A;  3X23 A;  1P5T A;  1RRP B;  2FJL A;  1X11 A;  3ULB A;  4KHA A;  2NMB A;  2M38 A;  2P0F A;  2RGN B;  3NSU A;  3WA0 A;  1E5W A;  4MY6 A;  4XWX A;  5C6R A;  4HAY B;  2CRF A;  2Q13 A;  4PQ0 A;  3OAN A;  5C5B B;  3ODW A;  1MKE A;  1FHW A;  4MT7 A;  1RJ2 A;  3VIA A;  2QKL A;  2LG1 A;  2EMT A;  4HB4 B;  3AJ4 A;  4A5K A;  2MFQ A;  4GN1 A;  1MK7 B;  1W1H A;  4K2O A;  3D8E A;  2QKM A;  1V61 A;  1OMW A;  4D0N B;  3DXE A;  2GCL A;  1V89 A;  2ROZ B;  3HK0 A;  5C5B A;  4B6H A;  4A6F B;  3KY9 A;  1WJM A;  2DKQ A;  1SGH A;  1FGY A;  2ROV A;  3QWM A;  3BJI A;  3AU4 A;  1UNQ A;  4K2P A;  4EMO A;  1P3R A;  1U2B A;  3U7D A;  3ODX A;  1TXD A;  1DBH A;  1K5D B;  1Q67 A;  2YS5 A;  1DDM A;  1UPQ A;  2LUL A;  2KCJ A;  3ODO A;  2COD A;  1W1G A;  1X1F A;  4TKN A;  3TCA A;  4CHJ A;  1PFJ A;  4EJN A;  1WGQ A;  2DTC A;  5D27 A;  5D3Y A;  1I7A A;  2K00 A;  4IAP A;  2COC A;  2GS0 A;  3PP2 A;  4HAV B;  1FHO A;  1N3H A;  2LOX A;  1GC6 A;  1ZC4 B;  2D11 A;  3UZT A;  3FSS A;  2I5F A;  1LW3 A;  2YT1 A;  2DFK A;  2H7D A;  3SUZ A;  1TJ6 A;  1WI1 A;  2J59 M;  2UZR A;  4HAT B;  1WJ1 A;  3PVU A;  3TVV A;  3P7Z A;  2DX5 A;  2HTH B;  4CYE A;  3GYO A;  1EGX A;  1XOD A;  3FM8 C;  4F7U P;  1BTK A;  2CAY A;  3CIK A;  2MWN B;  1H10 A;  2N23 A;  2CY4 A;  2GJY A;  2PZ1 A;  3SV1 A;  4GPT B;  1XX0 A;  2YRY A;  4DXA B;  4HHV A;  3DXD A;  1FHX A;  1ZVR A;  4ZRK A;  5FI0 A;  4A6H A;  5KCV A;  1AWE A;  1AQC A;  1QC6 A;  1J19 A;  1SHC A;  1Y19 B;  2E2X A;  5D3X A;  5DH9 B;  2H7E A;  1MIZ B;  5HE2 A;  3VOQ A;  2RNR B;  3TO1 A;  1KZG A;  4KAX B;  2EMS A;  3HW2 B;  2I5C A;  5CLQ B;  3A8P A;  4WVF B;  5D3V A;  3G9W A;  2KUP A;  5J3Q A;  2VRW B;  3MPX A;  1BTN A;  2P0D A;  2J0J A;  2DYQ A;  1V5U A;  2HE7 A;  3WYF B;  1UNP A;  1V88 A;  2GCJ A;  2LYD A;  3FEH A;  1U29 A;  4K17 A;  4Y94 A;  3P6A A;  2D10 A;  1WG7 A;  1XCG A;  2EJ8 A;  1QQG A;  1LB1 A;  2YSZ A;  3M1I B;  3MDB C;  1ZC3 B;  4F7H A;  2D9Z A;  2RSG A;  1XR0 B;  2KGX B;  1U5F A;  1X1G A;  3V5W A;  4HAU B;  2YVC A;  3SNH A;  4HDQ A;  1UNR A;  2MKR A;  3PVW A;  5KQ4 A;  1KZ7 A;  4GMX B;  4GXB A;  2YS3 A;  4HAX B;  4CHM A;  1DDW A;  2JP2 A;  3T06 A;  5GOW B;  1NI2 A;  3PVL A;  1H4R A;  4F7G A;  3ULC A;  1PMS A;  1TQZ A;  2R09 A;  2Z0O A;  1FB8 A;  4YL8 A;  5D3W A;  3BIN A;  2EC1 A;  5LON B;  1ISN A;  4EKU A;  3LJU X;  1U5D A;  2IYB A;  2K2U A;  5C16 A;  2DKP A;  1B55 A;  1FAO A;  3QBV B;  1UEF A;  4HB2 B;  5DHA B;  5KQ1 A;  4ZRI A;  4KHB B;  4P7I A;  2UZS A;  5HE0 A;  2XQN M;  1XKE A;  4HAW B;  2ELA A;  4NSW A;  2MDX A;  3N7C A;  1Z87 A;  3O96 A;  2DX1 A;  4KHO A;  2COF A;  2YF0 A;  2DLW A;  1WGU A;  2I1K A;  4HB0 B;  4WSF A;  1X86 A;  5HE3 A;  2X18 A;  1V5M A;  2W2X D;  5JHG A;  1MIX A;  3PSC A;  5LOP B;  2P0H A;  2LKO A;  3ML4 A;  3DXC A;  4IFS A;  4TYZ A;  1K5G B;  4DX9 0;  2D4Q A;  1MAI A;  4Z2M B;  3PEG A;  3AU5 A;  3PG7 A;  5FI1 A;  1X05 A;  2N0Y A;  2L1C A;  4MK0 A;  1M7E A;  3IVF A;  3ZVR A;  2W2X C;  3F5R A;  3KRX A;  1MPH A;  2COA A;  3SO6 A;  1J0W A;  2L2I A;  4Z2N A;  3U8Z A;  4DBB A;  2RUK B;  1U5G A;  2DHJ A;  2LOZ A;  2DN6 A;  2DHI A;  3HQC A;  5DIF B;  1FGZ A;  4DX8 A;  1UPR A;  4H8S A;  2RLO A;  1U5E A;  1WVH A;  2Z0P A;  4IOY X;  2VKI A;  1KI1 B;  1FOE A;  2RVB B;  3SYX A;  3RCP A;  3A8Q A;  3KZ1 A;  2AL6 A;  4A6K A;  2G35 A;  4C0A A;  2ZPY A;  5CLL B;  5HE1 A;  2DYN A;  5JHH A;  2M14 A;  3QIJ A;  1PLS A;  1ZM0 A;  2D2Q A;  4BBK A;  2YS1 A;  5DI9 B;  2DA0 A;  1EF1 A;  1DYN A;  3CXB B;  1P6S A;  4A6F A;  2Y8F A;  3KRW A;  1IRS A;  5EFX A;  1BWN A;  1XD4 A;  2DHK A;  2UVM A;  3D8F A;  1EAZ A;  5J3T A;  2D9W A;  2Z0Q A;  4K81 A;  3GYP A;  5L81 A;  4HDO A;  1DRO A;  2V76 A;  2ADZ A;  3KSY A;  4GMV A;  5DHF B;  1OQN A;  1MK9 B;  1NTV A;  4ZRJ A;  5JLJ B;  1GG3 A;  2R0D A;  4YON A;  4KVG B;  5JP4 A;  2W2W A;  1M7R A;  2J0M A;  3PZD A;  3F0W A;  1NTY A;  2AEH A;  2Y8G A;  4WJ7 A;  2I1J A;  2VSZ A;  2YT0 A;  4HB3 B;  2OTX A;  3TW1 A;  1ZSQ A;  2ELB A;  1BAK A;  2D9V A;  1Y5O A;  2D9Y A;  1EVH A;  4HAZ B;  1I2H A;  2BCJ A;  2NZ8 B;  2OQB A;  1V5P A;  4PNK A;  3TFM A;  1W1D A;  5J3Y A;  2Y7B A;  1OY2 A;  1NU2 A;  4L6E A;  4NY0 A;  4GZU A;  2D9X A;  3D8D A;  2CY5 A;  2P8V A;  3A98 B;  2IFS A;  1GC7 A;  5C79 A;  2K2J A;  1U27 A;  3ZDT A;  1DDV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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