The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
16
|
sequence length |
153
|
structure length |
153
|
Chain Sequence |
GSSGSSGLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIITSGSSGSSGSSGSSGLFRLRHFPCGNVNYGYQQQ
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
pubmed doi rcsb |
| molecule keywords |
Fibroblast growth factor receptor substrate 3 and ALK tyrosi
|
| molecule tags |
Signaling protein
|
| source organism |
Homo sapiens
|
| total genus |
16
|
| structure length |
153
|
| sequence length |
153
|
| ec nomenclature |
ec
2.7.10.1: Receptor protein-tyrosine kinase. |
| pdb deposition date | 2007-04-05 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF02174 | IRS | PTB domain (IRS-1 type) |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Roll | PH-domain like | PH-domain like |
#chains in the Genus database with same CATH superfamily 2KUQ A; 2YT2 A; #chains in the Genus database with same CATH topology 1KI1 B; 5HE2 A; 1FHX A; 2D9X A; 2P0H A; 2Z0P A; 5I2S A; 3VOQ A; 4HB3 B; 3CXB B; 4CHM A; 2W2X D; 3IVF A; 4GMX B; 4GN1 A; 4NSW A; 5HE0 A; 3ODX A; 2Z0Q A; 1NI2 A; 5DHF B; 3LJU X; 1V5U A; 3G9W A; 2AEH A; 2D9V A; 5D27 A; 1EAZ A; 2D11 A; 2Z59 A; 1GC7 A; 2D4Q A; 4A6F A; 1ZC4 B; 2DYN A; 4HAX B; 2CY5 A; 4D0N B; 4K81 A; 3WA0 A; 4BBK A; 4HAU B; 1BAK A; 1V61 A; 1J19 A; 2Q13 A; 2PZ1 A; 3A98 B; 1DBH A; 3DCX A; 3A8P A; 1XCG A; 1QQG A; 1MIZ B; 2DTC A; 2LG1 A; 2MWN B; 1UPQ A; 3TO1 A; 4HAT B; 1XX0 A; 3HSA A; 1W1H A; 2KUQ A; 3HW2 B; 1M7R A; 2NMB A; 3DXD A; 3FVC A; 4EKU A; 1GC6 A; 1MK7 B; 1UNP A; 4D6W A; 2YS1 A; 1U29 A; 3MDB C; 1AQC A; 4HDQ A; 4Y94 A; 5CLL B; 3TVV A; 1EGX A; 5J3Q A; 2I5F A; 1LW3 A; 3QWM A; 3SO6 A; 4A5K A; 2ZPY A; 3GYP A; 4L1R A; 1WVH A; 2GJY A; 2RVB B; 3AU4 A; 4IAP A; 1ZYI A; 2UZR A; 1SGH A; 2QKM A; 2D10 A; 3BJI A; 4K2P A; 3N7C A; 2JP2 A; 5JHH A; 3DXC A; 4DBB A; 1DRO A; 2HTH B; 1H10 A; 4PNK A; 3NW8 A; 2P8V A; 1LB1 A; 3D8F A; 1UNR A; 1V5M A; 1V5P A; 2D9W A; 2ELA A; 2YS5 A; 4F7U P; 2DHJ A; 2IFS A; 4HAW B; 3WYF B; 2YT1 A; 1GG3 A; 3GYO A; 5L81 A; 1MPH A; 2CY4 A; 3SNH A; 5DIF B; 2LYD A; 3ODO A; 4A6H A; 4B6H A; 3SYX A; 4Z2M B; 5JLJ B; 2MDX A; 3B77 A; 3ML4 A; 2NBV A; 2RRF A; 3PEG A; 4KHB B; 2ADZ A; 1BTK A; 2DA0 A; 2L1C A; 4HB2 B; 2D9Y A; 2KIG A; 3AJ4 A; 5EFX A; 5C16 A; 1MK9 B; 3A8Q A; 4A6K A; 5I2M A; 2DX1 A; 4GXB A; 4IOY X; 1N3H A; 4MK0 A; 1WGU A; 1Q67 A; 2KGX B; 3SV1 A; 1SHC A; 4GOU A; 1QC6 A; 1FHW A; 1X1G A; 2J0K A; 1P3R A; 2R0D A; 2ROV A; 4QJ4 B; 2G35 A; 1IRS A; 2X18 A; 5M4Y B; 4DX9 0; 1UEF A; 4MT7 A; 5C6R A; 2H7D A; 5LOP B; 4IFS A; 3FEH A; 2K8E A; 4DIX A; 1TJ6 A; 3P6A A; 1WI1 A; 3HK0 A; 1TXD A; 2VSZ A; 2R09 A; 2Y7B A; 4Z2N A; 3PSC A; 1DDM A; 4ZRJ A; 1PLS A; 1RJ2 A; 2NZ8 B; 3ZVR A; 2M14 A; 2Z4D A; 5FI0 A; 1W1D A; 3PVL A; 1KZG A; 4YL8 A; 2DFK A; 2N23 A; 2EC1 A; 2YVC A; 1V89 A; 4F7G A; 3BIN A; 1K5D B; 1B55 A; 1DYN A; 5C5B B; 2KUP A; 2GUM A; 2ROZ B; 2ZKM X; 1U5F A; 4QXA B; 2M38 A; 2YT2 A; 4MY6 A; 5KQ1 A; 1X1F A; 2IYB A; 2P0F A; 1ZM0 A; 2DLW A; 5D3W A; 1OY2 A; 1P6S A; 1Z87 A; 2EMS A; 2LKO A; 5LON B; 5IRS A; 4TKN A; 2FJL A; 2P0D A; 4TYZ A; 2UZS A; 2K00 A; 3KZ1 A; 3FM8 C; 4GPT B; 5KQ4 A; 5DI9 B; 4CSQ A; 5LG4 B; 5HE1 A; 1NTY A; 2QKL A; 4HAV B; 3U12 A; 3QIJ A; 2OQB A; 4DXA B; 1MIX A; 2AL6 A; 1X86 A; 3U8Z A; 2UVM A; 4F7H A; 2BCJ A; 4DX8 A; 1U2B A; 2KIE A; 3PZD A; 2K49 A; 2RNR B; 1RRP B; 2YSZ A; 2I1K A; 4KHB A; 3TCA A; 1NTV A; 3TW1 A; 4ZRK A; 3NWD A; 2J59 M; 1I2H A; 1FGY A; 2RUK B; 3OAN A; 2GCL A; 2K2U A; 3QBV B; 5D3Y A; 1BWN A; 1UPR A; 1I7A A; 3KRX A; 1DDV A; 3NWA A; 4PQ0 A; 2W2W A; 2Z0O A; 4K17 A; 4EMO A; 4P7I A; 3KRW A; 1Y5O A; 2HE7 A; 4OT1 A; 1K5G B; 2FJU B; 1EVH A; 1MKE A; 5D3V A; 2V76 A; 2CRF A; 3UZT A; 1PFJ A; 1U5G A; 4NY0 A; 4GMV A; 1TQZ A; 2LUL A; 3ULC A; 5J3Y A; 1W1G A; 2DN6 A; 2I5C A; 1P5T A; 2J0J A; 1BTN A; 1J0W A; 1KZ7 A; 2XQN M; 1ZC3 B; 3D8D A; 3ULB A; 2YS3 A; 4K2O A; 3CIK A; 5HE3 A; 1XR0 B; 2DKQ A; 5DHA B; 5DH9 B; 3A58 A; 1H4R A; 1X05 A; 4H8S A; 2D2Q A; 2KR0 A; 2DHI A; 1ZVR A; 1FAO A; 4HB4 B; 4CHJ A; 2Y8F A; 3F5R A; 4KHO A; 1U27 A; 4WSF A; 1OQN A; 2DHK A; 4QJ5 B; 2GS0 A; 2GCJ A; 3AU5 A; 2YT0 A; 2KCJ A; 3RCP A; 2RSG A; 2COD A; 2VRW B; 3DXE A; 4HB0 B; 5C5B A; 1FOE A; 5KCV A; 1XOD A; 3TFM A; 4HSI A; 5J3T A; 2RLO A; 2RGN B; 1E5W A; 2LOZ A; 3NWF A; 2N0Y A; 4CYE A; 2CAY A; 3PVW A; 3ZDT A; 1Y19 B; 1WJ1 A; 2DX5 A; 1V88 A; 2VKI A; 1T77 A; 4A6F B; 3PP2 A; 3HQC A; 4HDO A; 2Z14 A; 3HIE A; 4C0A A; 1WJM A; 3V5W A; 2COC A; 1MI1 A; 5C79 A; 4L6E A; 3F0W A; 2ELB A; 1X11 A; 3KY9 A; 2YRY A; 3KSY A; 4HAY B; 3U7D A; 2W2X C; 3PG7 A; 3SUZ A; 2H7E A; 2EJ8 A; 3MPX A; 2EMT A; 2E2X A; 5GOW B; 1FGZ A; 2COF A; 2I1J A; 3D8E A; 3PVU A; 3OHM B; 1UNQ A; 3NSU A; 3FSS A; 1EF1 A; 1ZSQ A; 4EJN A; 5D3X A; 1XKE A; 3O96 A; 4ZRI A; 4YON A; 1AWE A; 1M7E A; 5JHG A; 3P7Z A; 4KAX B; 2COA A; 1PMS A; 3ODW A; 4KHA A; 1U5E A; 5CLQ B; 3M1I B; 1MAI A; 2R2Y A; 4HAZ B; 2L2I A; 3X23 A; 4KVG B; 2YF0 A; 4GZU A; 2LOX A; 4OSN A; 2D9Z A; 1WG7 A; 2MKR A; 1NU2 A; 4QJ3 B; 1ISN A; 1XD4 A; 2OTX A; 2Y8G A; 4HHV A; 2Z13 A; 4XWX A; 1WGQ A; 4WVF B; 1FHO A; 5JP4 A; 2MFQ A; 4GNK B; 2K2J A; 1FB8 A; 1U5D A; 2DKP A; 5FI1 A; 1DDW A; 4WJ7 A; 2DYQ A; 3VIA A; 3T06 A; 1OMW A; 2J0M A; #chains in the Genus database with same CATH homology 5I2M A; 1ZYI A; 2Z59 A; 3TO1 A; 4OT1 A; 4IOY X; 5I2S A; 3NWF A; 4IFS A; 2FJU B; 4CSQ A; 2KUQ A; 3A58 A; 5LG4 B; 4KHB A; 2K8E A; 2GUM A; 4DIX A; 2ZKM X; 3FVC A; 4Z2M B; 3TW1 A; 4QXA B; 4D6W A; 2KR0 A; 3NWD A; 2NBV A; 2Z13 A; 3NW8 A; 2RRF A; 2YT2 A; 4GOU A; 4KHA A; 4KHB B; 3TVV A; 2R2Y A; 3U12 A; 4KHO A; 4Z2N A; 2GCL A; 2Z14 A; 4GNK B; 4QJ5 B; 3HIE A; 2GCJ A; 3GYP A; 4L1R A; 2Z4D A; 3NWA A; 4PQ0 A; 4QJ4 B; 5IRS A; 2KIE A; 4OSN A; 2KIG A; 5M4Y B; 2K49 A; 3OHM B; 4HSI A; 3GYO A; 4QJ3 B; 3FSS A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
