2Z0PA

Crystal structure of ph domain of bruton's tyrosine kinase
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
167
structure length
158
Chain Sequence
AAVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQIL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the Bruton's tyrosine kinase PH domain with phosphatidylinositol
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Tyrosine-protein kinase BTK
total genus 34
structure length 158
sequence length 167
chains with identical sequence B, C, D
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2007-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF00779 BTK BTK motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 2z0pA00
2P0FA 1Y19B 1FOEA 3ODXA 3WA0A 1U5FA 1ZC4B 2LULA 2YS1A 2KUPA 5LOPB 1V61A 3DXEA 1KZGA 2YS5A 3KRWA 2YSZA 4WJ7A 1UPQA 4KHAA 1WJMA 2UZSA 1DBHA 5EFXA 3U8ZA 4HB0B 1U29A 2I1JA 1UNQA 2UVMA 2YRYA 1NTVA 5J3YA 5C79A 2L2IA 2DKQA 1W1HA 2J59M 3QWMA 3AU4A 5HE2A 4HB4B 3NSUA 2UZRA 2RVBB 5J3QA 3SV1A 1U2BA 4PQ0A 2RLOA 1TJ6A 2GS0A 3FEHA 3T06A 2CODA 1X1FA 1WG7A 2GCJA 2D9WA 1NI2A 2W2XD 1DROA 2PZ1A 2DX5A 3BJIA 4EKUA 2R0DA 2AL6A 3F0WA 3HW2B 2D9VA 2DA0A 4K81A 4KHBB 1BAKA 3RCPA 5JP4A 1M7RA 3GYOA 5FI1A 1UNRA 2Z0PA 4XWXA 3TCAA 2ZPYA 2ELBA 2N0YA 2X18A 1FGYA 2FJLA 4GMVA 5C5BB 2LG1A 4HATB 3CXBB 2EJ8A 1P5TA 2D10A 4C0AA 5GOWB 4IFSA 1B55A 2OQBA 3LJUX 5HE1A 2ADZA 3TFMA 1DYNA 2IYBA 4K2OA 4D0NB 1N3HA 2EMSA 3PP2A 3AU5A 5CLLB 3SO6A 1ZC3B 5D27A 1SGHA 1MPHA 3D8EA 2CY5A 1UEFA 3P7ZA 3A98B 1MAIA 2KCJA 1WGUA 2OTXA 4MK0A 4CHMA 1U5GA 2N23A 1FHXA 3WYFB 1Y5OA 3M1IB 2ROZB 5C5BA 4DBBA 2DHJA 4GMXB 1GC7A 1MKEA 3FM8C 1X11A 2DYQA 4YONA 3KZ1A 2DFKA 5HE0A 1LB1A 5DHFB 2RUKB 3PEGA 2MWNB 2MKRA 1QQGA 1TQZA 3OANA 1GG3A 1FAOA 4DX90 3ZDTA 1I7AA 2M14A 1DDMA 4IOYX 3VOQA 1FGZA 2YT0A 1WJ1A 3PVLA 1W1DA 2VKIA 3G9WA 4GPTB 1XX0A 3F5RA 3CIKA 2COCA 1EGXA 4Z2MB 2D9YA 3TVVA 1UNPA 2I5CA 4HB3B 3KRXA 3VIAA 1H4RA 3DXCA 5D3XA 2LOZA 2COAA 3AJ4A 1EAZA 2YT1A 2L1CA 2Z0OA 4A6HA 3TO1A 2H7DA 3V5WA 2MFQA 3ODWA 2K00A 4B6HA 1PFJA 2DYNA 2W2WA 5D3WA 4HAUB 2LKOA 2DX1A 1MIXA 2QKLA 4TKNA 1ISNA 1MK7B 1BTKA 4HB2B 3KSYA 2LOXA 3KY9A 4NY0A 2P8VA 1AWEA 5J3TA 2RSGA 3UZTA 4NSWA 4F7UP 2DTCA 4K2PA 1PLSA 1BWNA 2DHKA 1FHWA 3MDBC 2P0DA 1FHOA 2K2JA 4F7GA 5JLJB 2YVCA 2CRFA 2H7EA 2K2UA 5DI9B 4Y94A 2J0KA 4MY6A 1EF1A 1XODA 2GJYA 2W2XC 5C6RA 1UPRA 4IAPA 2ELAA 5D3YA 2G35A 5JHGA 4A6FB 1WVHA 2Y8FA 1NTYA 2CAYA 1J19A 1P6SA 5CLQB 2HE7A 2D11A 1V89A 4BBKA 4ZRIA 3TW1A 2DLWA 1DDVA 2QKMA 3IVFA 2VRWB 1LW3A 1SHCA 1H10A 5DIFB 3PZDA 2YF0A 3PVWA 4PNKA 1XR0B 5C16A 2HTHB 5LONB 1ZM0A 3O96A 1XCGA 2Q13A 4HAXB 1K5DB 2P0HA 3QIJA 4TYZA 1WGQA 3U7DA 5DHAB 1V5MA 4GXBA 4HAWB 2KGXB 1AQCA 4K17A 4ZRKA 3SNHA 3N7CA 1MIZB 4HAVB 3HK0A 1ZSQA 1V88A 4MT7A 4A6FA 1K5GB 1BTNA 1U27A 2D9ZA 4A5KA 2J0MA 2CY4A 1U5EA 1KZ7A 4KVGB 1GC6A 5FI0A 2I5FA 4DX8A 3PVUA 3PG7A 1DDWA 2YS3A 5L81A 1IRSA 2NZ8B 3QBVB 5DH9B 5KQ4A 3GYPA 1X05A 1WI1A 1U5DA 2V76A 1I2HA 2COFA 4HHVA 2R09A 3ZVRA 2I1KA 3ULCA 3ML4A 1X1GA 1PMSA 4CYEA 4KHOA 4L6EA 1P3RA 2BCJA 5JHHA 4F7HA 2EC1A 1XD4A 3SUZA 2LYDA 1MK9B 2D4QA 4WSFA 2RNRB 3FSSA 1RJ2A 1X86A 4YL8A 2IFSA 5KCVA 1QC6A 3P6AA 1Z87A 3X23A 2AEHA 3A8QA 2VSZA 2D9XA 2JP2A 2J0JA 5D3VA 1FB8A 2DHIA 1EVHA 1V5PA 2DN6A 2ROVA 2Z0QA 4HAYB 5KQ1A 3MPXA 4HDOA 2M38A 2NMBA 1NU2A 1J0WA 2DKPA 1XKEA 4H8SA 3BINA 4EMOA 4P7IA 1KI1B 2RGNB 2XQNM 1OMWA 3DXDA 4EJNA 3D8FA 1TXDA 4GZUA 4GN1A 3SYXA 3A8PA 3PSCA 2E2XA 4HAZB 4DXAB 1E5WA 5HE3A 1Q67A 3ODOA 4Z2NA 3D8DA 2MDXA 1RRPB 2Y8GA 2EMTA 2Y7BA 1M7EA 4CHJA 4A6KA 4HDQA 2GCLA 1V5UA 4KAXB 3HQCA 2D2QA 1OQNA 4ZRJA 1ZVRA 1OY2A 3ULBA 1W1GA 4WVFB
chains in the Genus database with same CATH superfamily
2P0FA 1Y19B 1FOEA 3ODXA 3WA0A 1U5FA 1ZC4B 2LULA 2YS1A 2KUPA 5LG4B 1V61A 5LOPB 3DXEA 1KZGA 2YS5A 3KRWA 2YSZA 4WJ7A 1UPQA 4KHAA 1WJMA 2UZSA 1DBHA 5EFXA 3U8ZA 4HB0B 1U29A 2I1JA 1UNQA 2Z14A 1ZYIA 2KUQA 2UVMA 2YRYA 1NTVA 5J3YA 5C79A 2L2IA 2DKQA 3NWFA 1W1HA 2J59M 3QWMA 3AU4A 5HE2A 4HB4B 3NSUA 2UZRA 4D6WA 2RVBB 5J3QA 3SV1A 1U2BA 4PQ0A 2RLOA 1TJ6A 2GS0A 3FEHA 3T06A 2CODA 1X1FA 1WG7A 2GCJA 2Z4DA 2D9WA 1NI2A 2W2XD 1DROA 2PZ1A 2DX5A 3BJIA 4EKUA 2R0DA 2AL6A 3DCXA 3F0WA 3HW2B 3NW8A 2D9VA 2DA0A 4K81A 4KHBB 1BAKA 3RCPA 5JP4A 1M7RA 3GYOA 5IRSA 5FI1A 1UNRA 4HSIA 2Z0PA 4XWXA 3TCAA 2ZPYA 2ELBA 2N0YA 2X18A 1FGYA 2FJLA 4GMVA 5C5BB 2LG1A 4HATB 3CXBB 1T77A 1P5TA 2EJ8A 2D10A 4C0AA 5GOWB 4IFSA 1B55A 2OQBA 3LJUX 2KIEA 5HE1A 2ADZA 3TFMA 1DYNA 2IYBA 4K2OA 4D0NB 1N3HA 2EMSA 3PP2A 3AU5A 5CLLB 3SO6A 1ZC3B 5D27A 1SGHA 1MPHA 3D8EA 3HSAA 2CY5A 1UEFA 3P7ZA 4KHBA 3U12A 3A98B 1MAIA 2KCJA 1WGUA 2OTXA 4MK0A 4CHMA 1U5GA 2N23A 1FHXA 3B77A 3WYFB 1Y5OA 3M1IB 2ROZB 5C5BA 4DBBA 2DHJA 3NWDA 4GMXB 1GC7A 1MKEA 3FM8C 1X11A 2DYQA 4YONA 3KZ1A 2DFKA 5HE0A 1LB1A 5DHFB 2RUKB 3PEGA 2MWNB 2MKRA 1QQGA 1TQZA 3OANA 1GG3A 1FAOA 2Z59A 4DX90 3ZDTA 1I7AA 2M14A 2NBVA 4GOUA 1DDMA 4IOYX 3VOQA 1FGZA 2YT0A 1WJ1A 3PVLA 1W1DA 2VKIA 3G9WA 4GPTB 1XX0A 3F5RA 3CIKA 2COCA 1EGXA 4Z2MB 2D9YA 3TVVA 1UNPA 2I5CA 4HB3B 3KRXA 3VIAA 1MI1A 1H4RA 3DXCA 5D3XA 2LOZA 4OT1A 2K49A 2COAA 3AJ4A 1EAZA 2YT1A 2L1CA 2Z0OA 4A6HA 3TO1A 2H7DA 3V5WA 2MFQA 3ODWA 2K00A 4B6HA 1PFJA 2DYNA 2RRFA 2W2WA 5D3WA 4HAUB 2LKOA 2DX1A 1MIXA 2QKLA 4TKNA 1ISNA 1MK7B 2KIGA 1BTKA 3NWAA 3KSYA 4HB2B 2LOXA 3KY9A 4NY0A 2P8VA 1AWEA 5J3TA 2RSGA 3UZTA 4NSWA 4F7UP 2DTCA 4K2PA 1PLSA 1BWNA 2DHKA 1FHWA 3MDBC 2P0DA 1FHOA 2K2JA 4F7GA 4QXAB 5JLJB 2YVCA 2CRFA 2H7EA 2K2UA 5DI9B 4Y94A 2J0KA 4MY6A 1EF1A 1XODA 2GJYA 2W2XC 5C6RA 1UPRA 4IAPA 2ELAA 5D3YA 2G35A 5JHGA 4A6FB 1WVHA 2Y8FA 1NTYA 2CAYA 1J19A 1P6SA 5CLQB 2HE7A 2D11A 1V89A 5I2MA 4BBKA 4ZRIA 3TW1A 2DLWA 1DDVA 2QKMA 4L1RA 3OHMB 4OSNA 4GNKB 3IVFA 2VRWB 1LW3A 1SHCA 3FVCA 1H10A 5DIFB 3PZDA 2YF0A 3PVWA 4PNKA 1XR0B 5C16A 2HTHB 2GUMA 1ZM0A 2ZKMX 3O96A 5LONB 1XCGA 2Q13A 4HAXB 1K5DB 2P0HA 2YT2A 3QIJA 4TYZA 1WGQA 3U7DA 5DHAB 1V5MA 4GXBA 4HAWB 2KGXB 1AQCA 4K17A 4ZRKA 3SNHA 3N7CA 1MIZB 4HAVB 3HK0A 1ZSQA 1V88A 4MT7A 4A6FA 1K5GB 1BTNA 1U27A 2D9ZA 4A5KA 2J0MA 2CY4A 1U5EA 1KZ7A 2Z13A 4KVGB 1GC6A 5FI0A 2I5FA 4DX8A 3PVUA 3PG7A 1DDWA 5I2SA 2YS3A 5L81A 1IRSA 2NZ8B 3QBVB 5DH9B 5KQ4A 3GYPA 1X05A 1WI1A 1U5DA 2V76A 1I2HA 2COFA 2K8EA 2R09A 4HHVA 3ZVRA 2I1KA 3ULCA 3ML4A 1X1GA 1PMSA 4CYEA 4KHOA 4L6EA 1P3RA 2BCJA 5JHHA 4F7HA 2KR0A 2EC1A 1XD4A 3SUZA 2LYDA 1MK9B 2D4QA 4WSFA 2RNRB 3FSSA 1RJ2A 1X86A 4YL8A 2IFSA 5KCVA 1QC6A 3P6AA 1Z87A 3X23A 4QJ5B 2AEHA 3A8QA 2VSZA 2D9XA 2JP2A 2J0JA 5D3VA 1FB8A 2DHIA 1EVHA 1V5PA 2DN6A 2ROVA 2Z0QA 4HAYB 4CSQA 5KQ1A 3MPXA 4HDOA 2FJUB 2M38A 4QJ4B 2NMBA 1NU2A 1J0WA 2DKPA 1XKEA 4H8SA 3BINA 4EMOA 4P7IA 1KI1B 2RGNB 2XQNM 1OMWA 3DXDA 3HIEA 4EJNA 3D8FA 1TXDA 4GZUA 4GN1A 3SYXA 3A58A 3A8PA 3PSCA 2E2XA 4HAZB 4DXAB 1E5WA 5HE3A 2R2YA 1Q67A 3ODOA 4Z2NA 3D8DA 2MDXA 1RRPB 2Y8GA 2EMTA 2Y7BA 1M7EA 4CHJA 4DIXA 4A6KA 4HDQA 2GCLA 1V5UA 4KAXB 5M4YB 3HQCA 2D2QA 4QJ3B 1OQNA 4ZRJA 1ZVRA 1OY2A 3ULBA 1W1GA 4WVFB
chains in the Genus database with same CATH topology
2P0FA 1Y19B 1FOEA 3ODXA 3WA0A 1U5FA 1ZC4B 2LULA 2YS1A 2KUPA 5LOPB 1V61A 3DXEA 1KZGA 2YS5A 3KRWA 2YSZA 4WJ7A 1UPQA 4KHAA 1WJMA 2UZSA 1DBHA 5EFXA 3U8ZA 4HB0B 1U29A 2I1JA 1UNQA 2UVMA 2YRYA 1NTVA 5J3YA 5C79A 2L2IA 2DKQA 1W1HA 2J59M 3QWMA 3AU4A 5HE2A 4HB4B 3NSUA 2UZRA 2RVBB 5J3QA 3SV1A 1U2BA 4PQ0A 2RLOA 1TJ6A 2GS0A 3FEHA 3T06A 2CODA 1X1FA 1WG7A 2GCJA 2D9WA 1NI2A 2W2XD 1DROA 2PZ1A 2DX5A 3BJIA 4EKUA 2R0DA 2AL6A 3F0WA 3HW2B 2D9VA 2DA0A 4K81A 4KHBB 1BAKA 3RCPA 5JP4A 1M7RA 3GYOA 5FI1A 1UNRA 2Z0PA 4XWXA 3TCAA 2ZPYA 2ELBA 2N0YA 2X18A 1FGYA 2FJLA 4GMVA 5C5BB 2LG1A 4HATB 3CXBB 2EJ8A 1P5TA 2D10A 4C0AA 5GOWB 4IFSA 1B55A 2OQBA 3LJUX 5HE1A 2ADZA 3TFMA 1DYNA 2IYBA 4K2OA 4D0NB 1N3HA 2EMSA 3PP2A 3AU5A 5CLLB 3SO6A 1ZC3B 5D27A 1SGHA 1MPHA 3D8EA 2CY5A 1UEFA 3P7ZA 3A98B 1MAIA 2KCJA 1WGUA 2OTXA 4MK0A 4CHMA 1U5GA 2N23A 1FHXA 3WYFB 1Y5OA 3M1IB 2ROZB 5C5BA 4DBBA 2DHJA 4GMXB 1GC7A 1MKEA 3FM8C 1X11A 2DYQA 4YONA 3KZ1A 2DFKA 5HE0A 1LB1A 5DHFB 2RUKB 3PEGA 2MWNB 2MKRA 1QQGA 1TQZA 3OANA 1GG3A 1FAOA 4DX90 3ZDTA 1I7AA 2M14A 1DDMA 4IOYX 3VOQA 1FGZA 2YT0A 1WJ1A 3PVLA 1W1DA 2VKIA 3G9WA 4GPTB 1XX0A 3F5RA 3CIKA 2COCA 1EGXA 4Z2MB 2D9YA 3TVVA 1UNPA 2I5CA 4HB3B 3KRXA 3VIAA 1H4RA 3DXCA 5D3XA 2LOZA 2COAA 3AJ4A 1EAZA 2YT1A 2L1CA 2Z0OA 4A6HA 3TO1A 2H7DA 3V5WA 2MFQA 3ODWA 2K00A 4B6HA 1PFJA 2DYNA 2W2WA 5D3WA 4HAUB 2LKOA 2DX1A 1MIXA 2QKLA 4TKNA 1ISNA 1MK7B 1BTKA 4HB2B 3KSYA 2LOXA 3KY9A 4NY0A 2P8VA 1AWEA 5J3TA 2RSGA 3UZTA 4NSWA 4F7UP 2DTCA 4K2PA 1PLSA 1BWNA 2DHKA 1FHWA 3MDBC 2P0DA 1FHOA 2K2JA 4F7GA 5JLJB 2YVCA 2CRFA 2H7EA 2K2UA 5DI9B 4Y94A 2J0KA 4MY6A 1EF1A 1XODA 2GJYA 2W2XC 5C6RA 1UPRA 4IAPA 2ELAA 5D3YA 2G35A 5JHGA 4A6FB 1WVHA 2Y8FA 1NTYA 2CAYA 1J19A 1P6SA 5CLQB 2HE7A 2D11A 1V89A 4BBKA 4ZRIA 3TW1A 2DLWA 1DDVA 2QKMA 3IVFA 2VRWB 1LW3A 1SHCA 1H10A 5DIFB 3PZDA 2YF0A 3PVWA 4PNKA 1XR0B 5C16A 2HTHB 5LONB 1ZM0A 3O96A 1XCGA 2Q13A 4HAXB 1K5DB 2P0HA 3QIJA 4TYZA 1WGQA 3U7DA 5DHAB 1V5MA 4GXBA 4HAWB 2KGXB 1AQCA 4K17A 4ZRKA 3SNHA 3N7CA 1MIZB 4HAVB 3HK0A 1ZSQA 1V88A 4MT7A 4A6FA 1K5GB 1BTNA 1U27A 2D9ZA 4A5KA 2J0MA 2CY4A 1U5EA 1KZ7A 4KVGB 1GC6A 5FI0A 2I5FA 4DX8A 3PVUA 3PG7A 1DDWA 2YS3A 5L81A 1IRSA 2NZ8B 3QBVB 5DH9B 5KQ4A 3GYPA 1X05A 1WI1A 1U5DA 2V76A 1I2HA 2COFA 4HHVA 2R09A 3ZVRA 2I1KA 3ULCA 3ML4A 1X1GA 1PMSA 4CYEA 4KHOA 4L6EA 1P3RA 2BCJA 5JHHA 4F7HA 2EC1A 1XD4A 3SUZA 2LYDA 1MK9B 2D4QA 4WSFA 2RNRB 3FSSA 1RJ2A 1X86A 4YL8A 2IFSA 5KCVA 1QC6A 3P6AA 1Z87A 3X23A 2AEHA 3A8QA 2VSZA 2D9XA 2JP2A 2J0JA 5D3VA 1FB8A 2DHIA 1EVHA 1V5PA 2DN6A 2ROVA 2Z0QA 4HAYB 5KQ1A 3MPXA 4HDOA 2M38A 2NMBA 1NU2A 1J0WA 2DKPA 1XKEA 4H8SA 3BINA 4EMOA 4P7IA 1KI1B 2RGNB 2XQNM 1OMWA 3DXDA 4EJNA 3D8FA 1TXDA 4GZUA 4GN1A 3SYXA 3A8PA 3PSCA 2E2XA 4HAZB 4DXAB 1E5WA 5HE3A 1Q67A 3ODOA 4Z2NA 3D8DA 2MDXA 1RRPB 2Y8GA 2EMTA 2Y7BA 1M7EA 4CHJA 4A6KA 4HDQA 2GCLA 1V5UA 4KAXB 3HQCA 2D2QA 1OQNA 4ZRJA 1ZVRA 1OY2A 3ULBA 1W1GA 4WVFB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P0F A;  1Y19 B;  1FOE A;  3ODX A;  3WA0 A;  1U5F A;  1ZC4 B;  2LUL A;  2YS1 A;  2KUP A;  5LOP B;  1V61 A;  3DXE A;  1KZG A;  2YS5 A;  3KRW A;  2YSZ A;  4WJ7 A;  1UPQ A;  4KHA A;  1WJM A;  2UZS A;  1DBH A;  5EFX A;  3U8Z A;  4HB0 B;  1U29 A;  2I1J A;  1UNQ A;  2UVM A;  2YRY A;  1NTV A;  5J3Y A;  5C79 A;  2L2I A;  2DKQ A;  1W1H A;  2J59 M;  3QWM A;  3AU4 A;  5HE2 A;  4HB4 B;  3NSU A;  2UZR A;  2RVB B;  5J3Q A;  3SV1 A;  1U2B A;  4PQ0 A;  2RLO A;  1TJ6 A;  2GS0 A;  3FEH A;  3T06 A;  2COD A;  1X1F A;  1WG7 A;  2GCJ A;  2D9W A;  1NI2 A;  2W2X D;  1DRO A;  2PZ1 A;  2DX5 A;  3BJI A;  4EKU A;  2R0D A;  2AL6 A;  3F0W A;  3HW2 B;  2D9V A;  2DA0 A;  4K81 A;  4KHB B;  1BAK A;  3RCP A;  5JP4 A;  1M7R A;  3GYO A;  5FI1 A;  1UNR A;  2Z0P A;  4XWX A;  3TCA A;  2ZPY A;  2ELB A;  2N0Y A;  2X18 A;  1FGY A;  2FJL A;  4GMV A;  5C5B B;  2LG1 A;  4HAT B;  3CXB B;  2EJ8 A;  1P5T A;  2D10 A;  4C0A A;  5GOW B;  4IFS A;  1B55 A;  2OQB A;  3LJU X;  5HE1 A;  2ADZ A;  3TFM A;  1DYN A;  2IYB A;  4K2O A;  4D0N B;  1N3H A;  2EMS A;  3PP2 A;  3AU5 A;  5CLL B;  3SO6 A;  1ZC3 B;  5D27 A;  1SGH A;  1MPH A;  3D8E A;  2CY5 A;  1UEF A;  3P7Z A;  3A98 B;  1MAI A;  2KCJ A;  1WGU A;  2OTX A;  4MK0 A;  4CHM A;  1U5G A;  2N23 A;  1FHX A;  3WYF B;  1Y5O A;  3M1I B;  2ROZ B;  5C5B A;  4DBB A;  2DHJ A;  4GMX B;  1GC7 A;  1MKE A;  3FM8 C;  1X11 A;  2DYQ A;  4YON A;  3KZ1 A;  2DFK A;  5HE0 A;  1LB1 A;  5DHF B;  2RUK B;  3PEG A;  2MWN B;  2MKR A;  1QQG A;  1TQZ A;  3OAN A;  1GG3 A;  1FAO A;  4DX9 0;  3ZDT A;  1I7A A;  2M14 A;  1DDM A;  4IOY X;  3VOQ A;  1FGZ A;  2YT0 A;  1WJ1 A;  3PVL A;  1W1D A;  2VKI A;  3G9W A;  4GPT B;  1XX0 A;  3F5R A;  3CIK A;  2COC A;  1EGX A;  4Z2M B;  2D9Y A;  3TVV A;  1UNP A;  2I5C A;  4HB3 B;  3KRX A;  3VIA A;  1H4R A;  3DXC A;  5D3X A;  2LOZ A;  2COA A;  3AJ4 A;  1EAZ A;  2YT1 A;  2L1C A;  2Z0O A;  4A6H A;  3TO1 A;  2H7D A;  3V5W A;  2MFQ A;  3ODW A;  2K00 A;  4B6H A;  1PFJ A;  2DYN A;  2W2W A;  5D3W A;  4HAU B;  2LKO A;  2DX1 A;  1MIX A;  2QKL A;  4TKN A;  1ISN A;  1MK7 B;  1BTK A;  4HB2 B;  3KSY A;  2LOX A;  3KY9 A;  4NY0 A;  2P8V A;  1AWE A;  5J3T A;  2RSG A;  3UZT A;  4NSW A;  4F7U P;  2DTC A;  4K2P A;  1PLS A;  1BWN A;  2DHK A;  1FHW A;  3MDB C;  2P0D A;  1FHO A;  2K2J A;  4F7G A;  5JLJ B;  2YVC A;  2CRF A;  2H7E A;  2K2U A;  5DI9 B;  4Y94 A;  2J0K A;  4MY6 A;  1EF1 A;  1XOD A;  2GJY A;  2W2X C;  5C6R A;  1UPR A;  4IAP A;  2ELA A;  5D3Y A;  2G35 A;  5JHG A;  4A6F B;  1WVH A;  2Y8F A;  1NTY A;  2CAY A;  1J19 A;  1P6S A;  5CLQ B;  2HE7 A;  2D11 A;  1V89 A;  4BBK A;  4ZRI A;  3TW1 A;  2DLW A;  1DDV A;  2QKM A;  3IVF A;  2VRW B;  1LW3 A;  1SHC A;  1H10 A;  5DIF B;  3PZD A;  2YF0 A;  3PVW A;  4PNK A;  1XR0 B;  5C16 A;  2HTH B;  5LON B;  1ZM0 A;  3O96 A;  1XCG A;  2Q13 A;  4HAX B;  1K5D B;  2P0H A;  3QIJ A;  4TYZ A;  1WGQ A;  3U7D A;  5DHA B;  1V5M A;  4GXB A;  4HAW B;  2KGX B;  1AQC A;  4K17 A;  4ZRK A;  3SNH A;  3N7C A;  1MIZ B;  4HAV B;  3HK0 A;  1ZSQ A;  1V88 A;  4MT7 A;  4A6F A;  1K5G B;  1BTN A;  1U27 A;  2D9Z A;  4A5K A;  2J0M A;  2CY4 A;  1U5E A;  1KZ7 A;  4KVG B;  1GC6 A;  5FI0 A;  2I5F A;  4DX8 A;  3PVU A;  3PG7 A;  1DDW A;  2YS3 A;  5L81 A;  1IRS A;  2NZ8 B;  3QBV B;  5DH9 B;  5KQ4 A;  3GYP A;  1X05 A;  1WI1 A;  1U5D A;  2V76 A;  1I2H A;  2COF A;  4HHV A;  2R09 A;  3ZVR A;  2I1K A;  3ULC A;  3ML4 A;  1X1G A;  1PMS A;  4CYE A;  4KHO A;  4L6E A;  1P3R A;  2BCJ A;  5JHH A;  4F7H A;  2EC1 A;  1XD4 A;  3SUZ A;  2LYD A;  1MK9 B;  2D4Q A;  4WSF A;  2RNR B;  3FSS A;  1RJ2 A;  1X86 A;  4YL8 A;  2IFS A;  5KCV A;  1QC6 A;  3P6A A;  1Z87 A;  3X23 A;  2AEH A;  3A8Q A;  2VSZ A;  2D9X A;  2JP2 A;  2J0J A;  5D3V A;  1FB8 A;  2DHI A;  1EVH A;  1V5P A;  2DN6 A;  2ROV A;  2Z0Q A;  4HAY B;  5KQ1 A;  3MPX A;  4HDO A;  2M38 A;  2NMB A;  1NU2 A;  1J0W A;  2DKP A;  1XKE A;  4H8S A;  3BIN A;  4EMO A;  4P7I A;  1KI1 B;  2RGN B;  2XQN M;  1OMW A;  3DXD A;  4EJN A;  3D8F A;  1TXD A;  4GZU A;  4GN1 A;  3SYX A;  3A8P A;  3PSC A;  2E2X A;  4HAZ B;  4DXA B;  1E5W A;  5HE3 A;  1Q67 A;  3ODO A;  4Z2N A;  3D8D A;  2MDX A;  1RRP B;  2Y8G A;  2EMT A;  2Y7B A;  1M7E A;  4CHJ A;  4A6K A;  4HDQ A;  2GCL A;  1V5U A;  4KAX B;  3HQC A;  2D2Q A;  1OQN A;  4ZRJ A;  1ZVR A;  1OY2 A;  3ULB A;  1W1G A;  4WVF B; 
#chains in the Genus database with same CATH topology
 2P0F A;  1Y19 B;  1FOE A;  3ODX A;  3WA0 A;  1U5F A;  1ZC4 B;  2LUL A;  2YS1 A;  2KUP A;  5LG4 B;  1V61 A;  5LOP B;  3DXE A;  1KZG A;  2YS5 A;  3KRW A;  2YSZ A;  4WJ7 A;  1UPQ A;  4KHA A;  1WJM A;  2UZS A;  1DBH A;  5EFX A;  3U8Z A;  4HB0 B;  1U29 A;  2I1J A;  1UNQ A;  2Z14 A;  1ZYI A;  2KUQ A;  2UVM A;  2YRY A;  1NTV A;  5J3Y A;  5C79 A;  2L2I A;  2DKQ A;  3NWF A;  1W1H A;  2J59 M;  3QWM A;  3AU4 A;  5HE2 A;  4HB4 B;  3NSU A;  2UZR A;  4D6W A;  2RVB B;  5J3Q A;  3SV1 A;  1U2B A;  4PQ0 A;  2RLO A;  1TJ6 A;  2GS0 A;  3FEH A;  3T06 A;  2COD A;  1X1F A;  1WG7 A;  2GCJ A;  2Z4D A;  2D9W A;  1NI2 A;  2W2X D;  1DRO A;  2PZ1 A;  2DX5 A;  3BJI A;  4EKU A;  2R0D A;  2AL6 A;  3DCX A;  3F0W A;  3HW2 B;  3NW8 A;  2D9V A;  2DA0 A;  4K81 A;  4KHB B;  1BAK A;  3RCP A;  5JP4 A;  1M7R A;  3GYO A;  5IRS A;  5FI1 A;  1UNR A;  4HSI A;  2Z0P A;  4XWX A;  3TCA A;  2ZPY A;  2ELB A;  2N0Y A;  2X18 A;  1FGY A;  2FJL A;  4GMV A;  5C5B B;  2LG1 A;  4HAT B;  3CXB B;  1T77 A;  1P5T A;  2EJ8 A;  2D10 A;  4C0A A;  5GOW B;  4IFS A;  1B55 A;  2OQB A;  3LJU X;  2KIE A;  5HE1 A;  2ADZ A;  3TFM A;  1DYN A;  2IYB A;  4K2O A;  4D0N B;  1N3H A;  2EMS A;  3PP2 A;  3AU5 A;  5CLL B;  3SO6 A;  1ZC3 B;  5D27 A;  1SGH A;  1MPH A;  3D8E A;  3HSA A;  2CY5 A;  1UEF A;  3P7Z A;  4KHB A;  3U12 A;  3A98 B;  1MAI A;  2KCJ A;  1WGU A;  2OTX A;  4MK0 A;  4CHM A;  1U5G A;  2N23 A;  1FHX A;  3B77 A;  3WYF B;  1Y5O A;  3M1I B;  2ROZ B;  5C5B A;  4DBB A;  2DHJ A;  3NWD A;  4GMX B;  1GC7 A;  1MKE A;  3FM8 C;  1X11 A;  2DYQ A;  4YON A;  3KZ1 A;  2DFK A;  5HE0 A;  1LB1 A;  5DHF B;  2RUK B;  3PEG A;  2MWN B;  2MKR A;  1QQG A;  1TQZ A;  3OAN A;  1GG3 A;  1FAO A;  2Z59 A;  4DX9 0;  3ZDT A;  1I7A A;  2M14 A;  2NBV A;  4GOU A;  1DDM A;  4IOY X;  3VOQ A;  1FGZ A;  2YT0 A;  1WJ1 A;  3PVL A;  1W1D A;  2VKI A;  3G9W A;  4GPT B;  1XX0 A;  3F5R A;  3CIK A;  2COC A;  1EGX A;  4Z2M B;  2D9Y A;  3TVV A;  1UNP A;  2I5C A;  4HB3 B;  3KRX A;  3VIA A;  1MI1 A;  1H4R A;  3DXC A;  5D3X A;  2LOZ A;  4OT1 A;  2K49 A;  2COA A;  3AJ4 A;  1EAZ A;  2YT1 A;  2L1C A;  2Z0O A;  4A6H A;  3TO1 A;  2H7D A;  3V5W A;  2MFQ A;  3ODW A;  2K00 A;  4B6H A;  1PFJ A;  2DYN A;  2RRF A;  2W2W A;  5D3W A;  4HAU B;  2LKO A;  2DX1 A;  1MIX A;  2QKL A;  4TKN A;  1ISN A;  1MK7 B;  2KIG A;  1BTK A;  3NWA A;  3KSY A;  4HB2 B;  2LOX A;  3KY9 A;  4NY0 A;  2P8V A;  1AWE A;  5J3T A;  2RSG A;  3UZT A;  4NSW A;  4F7U P;  2DTC A;  4K2P A;  1PLS A;  1BWN A;  2DHK A;  1FHW A;  3MDB C;  2P0D A;  1FHO A;  2K2J A;  4F7G A;  4QXA B;  5JLJ B;  2YVC A;  2CRF A;  2H7E A;  2K2U A;  5DI9 B;  4Y94 A;  2J0K A;  4MY6 A;  1EF1 A;  1XOD A;  2GJY A;  2W2X C;  5C6R A;  1UPR A;  4IAP A;  2ELA A;  5D3Y A;  2G35 A;  5JHG A;  4A6F B;  1WVH A;  2Y8F A;  1NTY A;  2CAY A;  1J19 A;  1P6S A;  5CLQ B;  2HE7 A;  2D11 A;  1V89 A;  5I2M A;  4BBK A;  4ZRI A;  3TW1 A;  2DLW A;  1DDV A;  2QKM A;  4L1R A;  3OHM B;  4OSN A;  4GNK B;  3IVF A;  2VRW B;  1LW3 A;  1SHC A;  3FVC A;  1H10 A;  5DIF B;  3PZD A;  2YF0 A;  3PVW A;  4PNK A;  1XR0 B;  5C16 A;  2HTH B;  2GUM A;  1ZM0 A;  2ZKM X;  3O96 A;  5LON B;  1XCG A;  2Q13 A;  4HAX B;  1K5D B;  2P0H A;  2YT2 A;  3QIJ A;  4TYZ A;  1WGQ A;  3U7D A;  5DHA B;  1V5M A;  4GXB A;  4HAW B;  2KGX B;  1AQC A;  4K17 A;  4ZRK A;  3SNH A;  3N7C A;  1MIZ B;  4HAV B;  3HK0 A;  1ZSQ A;  1V88 A;  4MT7 A;  4A6F A;  1K5G B;  1BTN A;  1U27 A;  2D9Z A;  4A5K A;  2J0M A;  2CY4 A;  1U5E A;  1KZ7 A;  2Z13 A;  4KVG B;  1GC6 A;  5FI0 A;  2I5F A;  4DX8 A;  3PVU A;  3PG7 A;  1DDW A;  5I2S A;  2YS3 A;  5L81 A;  1IRS A;  2NZ8 B;  3QBV B;  5DH9 B;  5KQ4 A;  3GYP A;  1X05 A;  1WI1 A;  1U5D A;  2V76 A;  1I2H A;  2COF A;  2K8E A;  2R09 A;  4HHV A;  3ZVR A;  2I1K A;  3ULC A;  3ML4 A;  1X1G A;  1PMS A;  4CYE A;  4KHO A;  4L6E A;  1P3R A;  2BCJ A;  5JHH A;  4F7H A;  2KR0 A;  2EC1 A;  1XD4 A;  3SUZ A;  2LYD A;  1MK9 B;  2D4Q A;  4WSF A;  2RNR B;  3FSS A;  1RJ2 A;  1X86 A;  4YL8 A;  2IFS A;  5KCV A;  1QC6 A;  3P6A A;  1Z87 A;  3X23 A;  4QJ5 B;  2AEH A;  3A8Q A;  2VSZ A;  2D9X A;  2JP2 A;  2J0J A;  5D3V A;  1FB8 A;  2DHI A;  1EVH A;  1V5P A;  2DN6 A;  2ROV A;  2Z0Q A;  4HAY B;  4CSQ A;  5KQ1 A;  3MPX A;  4HDO A;  2FJU B;  2M38 A;  4QJ4 B;  2NMB A;  1NU2 A;  1J0W A;  2DKP A;  1XKE A;  4H8S A;  3BIN A;  4EMO A;  4P7I A;  1KI1 B;  2RGN B;  2XQN M;  1OMW A;  3DXD A;  3HIE A;  4EJN A;  3D8F A;  1TXD A;  4GZU A;  4GN1 A;  3SYX A;  3A58 A;  3A8P A;  3PSC A;  2E2X A;  4HAZ B;  4DXA B;  1E5W A;  5HE3 A;  2R2Y A;  1Q67 A;  3ODO A;  4Z2N A;  3D8D A;  2MDX A;  1RRP B;  2Y8G A;  2EMT A;  2Y7B A;  1M7E A;  4CHJ A;  4DIX A;  4A6K A;  4HDQ A;  2GCL A;  1V5U A;  4KAX B;  5M4Y B;  3HQC A;  2D2Q A;  4QJ3 B;  1OQN A;  4ZRJ A;  1ZVR A;  1OY2 A;  3ULB A;  1W1G A;  4WVF B; 
#chains in the Genus database with same CATH homology
 2P0F A;  1Y19 B;  1FOE A;  3ODX A;  3WA0 A;  1U5F A;  1ZC4 B;  2LUL A;  2YS1 A;  2KUP A;  5LOP B;  1V61 A;  3DXE A;  1KZG A;  2YS5 A;  3KRW A;  2YSZ A;  4WJ7 A;  1UPQ A;  4KHA A;  1WJM A;  2UZS A;  1DBH A;  5EFX A;  3U8Z A;  4HB0 B;  1U29 A;  2I1J A;  1UNQ A;  2UVM A;  2YRY A;  1NTV A;  5J3Y A;  5C79 A;  2L2I A;  2DKQ A;  1W1H A;  2J59 M;  3QWM A;  3AU4 A;  5HE2 A;  4HB4 B;  3NSU A;  2UZR A;  2RVB B;  5J3Q A;  3SV1 A;  1U2B A;  4PQ0 A;  2RLO A;  1TJ6 A;  2GS0 A;  3FEH A;  3T06 A;  2COD A;  1X1F A;  1WG7 A;  2GCJ A;  2D9W A;  1NI2 A;  2W2X D;  1DRO A;  2PZ1 A;  2DX5 A;  3BJI A;  4EKU A;  2R0D A;  2AL6 A;  3F0W A;  3HW2 B;  2D9V A;  2DA0 A;  4K81 A;  4KHB B;  1BAK A;  3RCP A;  5JP4 A;  1M7R A;  3GYO A;  5FI1 A;  1UNR A;  2Z0P A;  4XWX A;  3TCA A;  2ZPY A;  2ELB A;  2N0Y A;  2X18 A;  1FGY A;  2FJL A;  4GMV A;  5C5B B;  2LG1 A;  4HAT B;  3CXB B;  2EJ8 A;  1P5T A;  2D10 A;  4C0A A;  5GOW B;  4IFS A;  1B55 A;  2OQB A;  3LJU X;  5HE1 A;  2ADZ A;  3TFM A;  1DYN A;  2IYB A;  4K2O A;  4D0N B;  1N3H A;  2EMS A;  3PP2 A;  3AU5 A;  5CLL B;  3SO6 A;  1ZC3 B;  5D27 A;  1SGH A;  1MPH A;  3D8E A;  2CY5 A;  1UEF A;  3P7Z A;  3A98 B;  1MAI A;  2KCJ A;  1WGU A;  2OTX A;  4MK0 A;  4CHM A;  1U5G A;  2N23 A;  1FHX A;  3WYF B;  1Y5O A;  3M1I B;  2ROZ B;  5C5B A;  4DBB A;  2DHJ A;  4GMX B;  1GC7 A;  1MKE A;  3FM8 C;  1X11 A;  2DYQ A;  4YON A;  3KZ1 A;  2DFK A;  5HE0 A;  1LB1 A;  5DHF B;  2RUK B;  3PEG A;  2MWN B;  2MKR A;  1QQG A;  1TQZ A;  3OAN A;  1GG3 A;  1FAO A;  4DX9 0;  3ZDT A;  1I7A A;  2M14 A;  1DDM A;  4IOY X;  3VOQ A;  1FGZ A;  2YT0 A;  1WJ1 A;  3PVL A;  1W1D A;  2VKI A;  3G9W A;  4GPT B;  1XX0 A;  3F5R A;  3CIK A;  2COC A;  1EGX A;  4Z2M B;  2D9Y A;  3TVV A;  1UNP A;  2I5C A;  4HB3 B;  3KRX A;  3VIA A;  1H4R A;  3DXC A;  5D3X A;  2LOZ A;  2COA A;  3AJ4 A;  1EAZ A;  2YT1 A;  2L1C A;  2Z0O A;  4A6H A;  3TO1 A;  2H7D A;  3V5W A;  2MFQ A;  3ODW A;  2K00 A;  4B6H A;  1PFJ A;  2DYN A;  2W2W A;  5D3W A;  4HAU B;  2LKO A;  2DX1 A;  1MIX A;  2QKL A;  4TKN A;  1ISN A;  1MK7 B;  1BTK A;  4HB2 B;  3KSY A;  2LOX A;  3KY9 A;  4NY0 A;  2P8V A;  1AWE A;  5J3T A;  2RSG A;  3UZT A;  4NSW A;  4F7U P;  2DTC A;  4K2P A;  1PLS A;  1BWN A;  2DHK A;  1FHW A;  3MDB C;  2P0D A;  1FHO A;  2K2J A;  4F7G A;  5JLJ B;  2YVC A;  2CRF A;  2H7E A;  2K2U A;  5DI9 B;  4Y94 A;  2J0K A;  4MY6 A;  1EF1 A;  1XOD A;  2GJY A;  2W2X C;  5C6R A;  1UPR A;  4IAP A;  2ELA A;  5D3Y A;  2G35 A;  5JHG A;  4A6F B;  1WVH A;  2Y8F A;  1NTY A;  2CAY A;  1J19 A;  1P6S A;  5CLQ B;  2HE7 A;  2D11 A;  1V89 A;  4BBK A;  4ZRI A;  3TW1 A;  2DLW A;  1DDV A;  2QKM A;  3IVF A;  2VRW B;  1LW3 A;  1SHC A;  1H10 A;  5DIF B;  3PZD A;  2YF0 A;  3PVW A;  4PNK A;  1XR0 B;  5C16 A;  2HTH B;  5LON B;  1ZM0 A;  3O96 A;  1XCG A;  2Q13 A;  4HAX B;  1K5D B;  2P0H A;  3QIJ A;  4TYZ A;  1WGQ A;  3U7D A;  5DHA B;  1V5M A;  4GXB A;  4HAW B;  2KGX B;  1AQC A;  4K17 A;  4ZRK A;  3SNH A;  3N7C A;  1MIZ B;  4HAV B;  3HK0 A;  1ZSQ A;  1V88 A;  4MT7 A;  4A6F A;  1K5G B;  1BTN A;  1U27 A;  2D9Z A;  4A5K A;  2J0M A;  2CY4 A;  1U5E A;  1KZ7 A;  4KVG B;  1GC6 A;  5FI0 A;  2I5F A;  4DX8 A;  3PVU A;  3PG7 A;  1DDW A;  2YS3 A;  5L81 A;  1IRS A;  2NZ8 B;  3QBV B;  5DH9 B;  5KQ4 A;  3GYP A;  1X05 A;  1WI1 A;  1U5D A;  2V76 A;  1I2H A;  2COF A;  4HHV A;  2R09 A;  3ZVR A;  2I1K A;  3ULC A;  3ML4 A;  1X1G A;  1PMS A;  4CYE A;  4KHO A;  4L6E A;  1P3R A;  2BCJ A;  5JHH A;  4F7H A;  2EC1 A;  1XD4 A;  3SUZ A;  2LYD A;  1MK9 B;  2D4Q A;  4WSF A;  2RNR B;  3FSS A;  1RJ2 A;  1X86 A;  4YL8 A;  2IFS A;  5KCV A;  1QC6 A;  3P6A A;  1Z87 A;  3X23 A;  2AEH A;  3A8Q A;  2VSZ A;  2D9X A;  2JP2 A;  2J0J A;  5D3V A;  1FB8 A;  2DHI A;  1EVH A;  1V5P A;  2DN6 A;  2ROV A;  2Z0Q A;  4HAY B;  5KQ1 A;  3MPX A;  4HDO A;  2M38 A;  2NMB A;  1NU2 A;  1J0W A;  2DKP A;  1XKE A;  4H8S A;  3BIN A;  4EMO A;  4P7I A;  1KI1 B;  2RGN B;  2XQN M;  1OMW A;  3DXD A;  4EJN A;  3D8F A;  1TXD A;  4GZU A;  4GN1 A;  3SYX A;  3A8P A;  3PSC A;  2E2X A;  4HAZ B;  4DXA B;  1E5W A;  5HE3 A;  1Q67 A;  3ODO A;  4Z2N A;  3D8D A;  2MDX A;  1RRP B;  2Y8G A;  2EMT A;  2Y7B A;  1M7E A;  4CHJ A;  4A6K A;  4HDQ A;  2GCL A;  1V5U A;  4KAX B;  3HQC A;  2D2Q A;  1OQN A;  4ZRJ A;  1ZVR A;  1OY2 A;  3ULB A;  1W1G A;  4WVF B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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