2CY5A

Crystal structure of phosphotyrosine binding (ptb) domain of epidermal growth factor receptor pathway substrate-8 (eps8) related protein 1 from mus musculus (form-2 crystal)
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
130
structure length
130
Chain Sequence
MADVSQYHVNHLVTFCLGEEDGVHTVEDASRKLAVMDSQGRVWAQEMLLRVSPSQVTLLDPVSKEELESYPLDAIVRCDAVMPRGRSRSLLLLVCQEPERAQPDVHFFQGLLLGAELIREDIQGALQNYR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of phosphotyrosine binding (PTB) domain of epidermal growth factor receptor pathway substrate-8 (EPS8) related protein 1 from Mus musculus (form-2 crystal)
rcsb
molecule tags Signaling protein
source organism Mus musculus
molecule keywords epidermal growth factor receptor pathway substrate 8-like pr
total genus 29
structure length 130
sequence length 130
ec nomenclature
pdb deposition date 2005-07-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08416 PTB Phosphotyrosine-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 2cy5A00
2EC1A 2DHJA 1I2HA 1V5PA 2P8VA 3AU5A 1DBHA 5HE0A 5JHHA 5LOPB 2LOXA 2W2XC 5J3YA 3U8ZA 1OQNA 3SYXA 4HB4B 2D11A 1Q67A 2RGNB 2D9VA 1NTVA 1EAZA 5JHGA 4HHVA 1XODA 2D4QA 3GYOA 3FEHA 1XCGA 5D3WA 2YS3A 3ODOA 4HAVB 2BCJA 4CHJA 3D8EA 3OANA 4CHMA 3ZDTA 1EVHA 4HAUB 2AEHA 3X23A 2D2QA 3P6AA 2EMSA 3AJ4A 4ZRIA 5GOWB 3TO1A 1MIZB 1H10A 5J3TA 4BBKA 4MY6A 2CY5A 2LULA 2JP2A 2ELBA 2E2XA 3ODXA 1K5DB 2Z0PA 4GN1A 1WVHA 3BINA 5FI0A 4ZRKA 4GMVA 1WG7A 3CXBB 4F7GA 1GC7A 3GYPA 2LOZA 5HE3A 4A6FA 1UNPA 1UNQA 4HB0B 3PVUA 2J0MA 1KZGA 3SUZA 4A6FB 1ISNA 1M7RA 1U5DA 2I5FA 4KHBB 4HAWB 4EKUA 5DH9B 2MWNB 1MPHA 5DI9B 3TW1A 5HE2A 3CIKA 4KAXB 2QKMA 1UNRA 1ZVRA 1TQZA 4TYZA 1Z87A 5C79A 3WA0A 1ZC4B 2N0YA 1BTNA 5FI1A 2DLWA 2ROZB 1V89A 4HAYB 4DBBA 2DHIA 4YL8A 5JP4A 4KVGB 1DROA 3KRXA 2YVCA 1FHWA 1J19A 1WJMA 1FGYA 2MKRA 2D9WA 2DFKA 4WVFB 2VRWB 1PMSA 4B6HA 1AWEA 1MIXA 3QBVB 1DDMA 1XD4A 1FGZA 1P5TA 2KUPA 1FHOA 4HDOA 2P0DA 2VKIA 2CODA 5JLJB 2PZ1A 1X11A 2IFSA 3V5WA 2YS5A 1WGUA 4KHAA 4XWXA 3DXDA 2D9ZA 2M38A 4C0AA 5CLLB 4HATB 2DHKA 3KSYA 2YT1A 1NU2A 2G35A 1X86A 3HW2B 1RJ2A 1FB8A 1IRSA 2P0HA 2YS1A 1WGQA 4MT7A 1XKEA 4Z2NA 1TJ6A 3ULBA 3PVLA 4P7IA 4PNKA 1PLSA 1X05A 4A5KA 1QC6A 4GXBA 2Y7BA 2ELAA 3D8DA 3MPXA 4K2OA 2OTXA 1NTYA 2DA0A 2GS0A 3QIJA 1K5GB 3SO6A 1BAKA 2MDXA 1ZC3B 2EJ8A 2Z0OA 1ZSQA 2YT0A 3TFMA 2L1CA 2R0DA 4ZRJA 1DDVA 1OMWA 5EFXA 2Y8GA 1GC6A 4Z2MB 2YF0A 2D9XA 2EMTA 2VSZA 4K17A 3PEGA 3F5RA 2I1JA 2DKQA 4HAZB 3KZ1A 1V61A 2CY4A 4A6KA 2GCLA 1DYNA 1PFJA 1NI2A 2L2IA 1EGXA 4GZUA 1V5UA 3IVFA 4HAXB 2RNRB 3D8FA 3A98B 1KI1B 2YSZA 1WJ1A 2J0KA 4DX8A 3TCAA 5KQ1A 2K2UA 3QWMA 2DYNA 4MK0A 4KHOA 1GG3A 1MK7B 2P0FA 2DTCA 2Q13A 2N23A 1Y19B 1ZM0A 3DXCA 2NZ8B 2M14A 3ULCA 5DHFB 5KQ4A 3LJUX 1P6SA 2HTHB 1DDWA 1U5GA 2ROVA 4NSWA 3RCPA 1FOEA 3DXEA 1H4RA 2IYBA 2I1KA 4F7UP 4DXAB 1U2BA 5J3QA 2UZSA 1AQCA 1M7EA 2K00A 2R09A 4NY0A 1U29A 1U5FA 4CYEA 3WYFB 3M1IB 2DX5A 3PP2A 2W2WA 4EJNA 2RVBB 2UZRA 3A8QA 4F7HA 3PVWA 3FM8C 3P7ZA 2J59M 2LKOA 3KRWA 4YONA 4WJ7A 5KCVA 1BTKA 2RSGA 1SHCA 4K81A 1LB1A 4IOYX 1BWNA 5C6RA 1QQGA 4WSFA 2HE7A 5HE1A 3HQCA 5D27A 2COFA 2V76A 1J0WA 1UPRA 1UEFA 2X18A 2GJYA 1MAIA 2Z0QA 2LG1A 2KGXB 3U7DA 3ZVRA 1W1GA 2GCJA 4H8SA 1KZ7A 4GMXB 2ADZA 1U27A 4TKNA 1P3RA 1W1HA 2NMBA 3ODWA 1LW3A 4IFSA 3FSSA 4HB2B 4DX90 3T06A 1X1GA 2COAA 5L81A 1MK9B 2H7DA 2RUKB 2QKLA 4PQ0A 1OY2A 1FAOA 3KY9A 4HB3B 5DIFB 5LONB 1SGHA 3N7CA 1FHXA 2FJLA 3ML4A 5D3VA 2CRFA 1N3HA 2DKPA 2I5CA 3VIAA 4Y94A 1MKEA 1Y5OA 2YRYA 2LYDA 3PSCA 4EMOA 2AL6A 1TXDA 3VOQA 3BJIA 4K2PA 2COCA 2MFQA 2D9YA 2W2XD 3AU4A 2XQNM 2Y8FA 1I7AA 2DX1A 2DN6A 3F0WA 1X1FA 1U5EA 3G9WA 1EF1A 1UPQA 5CLQB 4HDQA 2D10A 1XR0B 5C16A 1W1DA 3MDBC 2J0JA 2RLOA 2UVMA 4A6HA 3UZTA 1B55A 3PG7A 1V88A 2KCJA 2OQBA 4GPTB 1WI1A 1E5WA 5DHAB 3A8PA 3TVVA 5C5BA 5D3YA 2K2JA 1RRPB 3O96A 4L6EA 2CAYA 4IAPA 5D3XA 3PZDA 2ZPYA 5C5BB 3HK0A 4D0NB 2DYQA 2H7EA 1XX0A 3SNHA 3SV1A 3NSUA 1V5MA
chains in the Genus database with same CATH superfamily
2EC1A 2DHJA 1I2HA 1V5PA 2P8VA 3AU5A 1DBHA 5HE0A 5JHHA 5LOPB 2LOXA 2W2XC 5J3YA 3U8ZA 1OQNA 3SYXA 4HB4B 2D11A 1Q67A 2RGNB 2D9VA 1NTVA 1EAZA 5JHGA 4HHVA 1XODA 2D4QA 3GYOA 3FEHA 2Z14A 1XCGA 5D3WA 2YS3A 3ODOA 4HAVB 2BCJA 4CHJA 3DCXA 3D8EA 3OANA 4CHMA 3ZDTA 1EVHA 4HAUB 2AEHA 3X23A 2D2QA 3P6AA 2EMSA 3AJ4A 4ZRIA 5GOWB 3TO1A 1MIZB 1H10A 5J3TA 4BBKA 4MY6A 2CY5A 2LULA 2JP2A 2ELBA 2E2XA 3ODXA 1K5DB 2Z0PA 4GN1A 1WVHA 3BINA 5FI0A 4ZRKA 4L1RA 4GMVA 1WG7A 3CXBB 4F7GA 4OSNA 1GC7A 3GYPA 2LOZA 4OT1A 5HE3A 4A6FA 1UNPA 4QXAB 1UNQA 4HB0B 3PVUA 5LG4B 2J0MA 3HSAA 1KZGA 2FJUB 3SUZA 4A6FB 1ISNA 1M7RA 1U5DA 2I5FA 4QJ4B 4KHBB 4HAWB 4EKUA 3A58A 5DH9B 2MWNB 1MPHA 5DI9B 3U12A 3TW1A 3B77A 5HE2A 3CIKA 4QJ3B 4KAXB 2QKMA 1UNRA 1ZVRA 1TQZA 4TYZA 1Z87A 5C79A 3WA0A 1ZC4B 2N0YA 1BTNA 4QJ5B 5FI1A 2DLWA 2ROZB 1V89A 4HAYB 4DBBA 2DHIA 4YL8A 5JP4A 4KVGB 1DROA 3KRXA 2YVCA 1FHWA 4HSIA 1J19A 1WJMA 1FGYA 2MKRA 2D9WA 2DFKA 4WVFB 5I2MA 2VRWB 1PMSA 4B6HA 1AWEA 1MIXA 3QBVB 1DDMA 1XD4A 1FGZA 1P5TA 2KUPA 1FHOA 4HDOA 2P0DA 2VKIA 2CODA 5JLJB 2PZ1A 1X11A 2IFSA 3V5WA 2YS5A 1WGUA 4KHAA 4XWXA 3DXDA 2D9ZA 2M38A 4C0AA 5CLLB 4HATB 2DHKA 3KSYA 2YT1A 2R2YA 1NU2A 2G35A 1X86A 3HW2B 1RJ2A 1FB8A 1IRSA 2Z59A 2P0HA 2YS1A 1WGQA 4MT7A 1XKEA 4Z2NA 1TJ6A 3ULBA 3PVLA 4P7IA 4PNKA 1PLSA 1X05A 4A5KA 1QC6A 4GXBA 2Y7BA 2ELAA 3D8DA 3MPXA 3NWDA 4K2OA 2OTXA 1NTYA 2DA0A 2GS0A 3QIJA 1K5GB 3SO6A 1BAKA 2KIGA 2MDXA 1ZC3B 2EJ8A 2YT2A 2Z0OA 4DIXA 1ZSQA 2YT0A 3TFMA 2L1CA 2R0DA 4ZRJA 1DDVA 1OMWA 5EFXA 2Y8GA 4CSQA 1GC6A 4Z2MB 3FVCA 4D6WA 2YF0A 1MI1A 2D9XA 2EMTA 2VSZA 4K17A 3PEGA 3F5RA 2I1JA 2DKQA 4HAZB 3KZ1A 1V61A 2CY4A 4A6KA 2GCLA 1DYNA 3NWAA 1NI2A 2L2IA 1EGXA 4GZUA 1V5UA 3IVFA 4HAXB 2RNRB 3D8FA 3A98B 1KI1B 2YSZA 1WJ1A 2J0KA 4DX8A 3TCAA 5KQ1A 2K2UA 3QWMA 2DYNA 4MK0A 4KHOA 1GG3A 1MK7B 2P0FA 2DTCA 2Q13A 2N23A 1Y19B 1ZM0A 3DXCA 2NZ8B 2M14A 2GUMA 3ULCA 5DHFB 5KQ4A 3LJUX 1P6SA 2HTHB 1DDWA 1U5GA 2ROVA 4NSWA 3RCPA 1FOEA 3DXEA 1H4RA 2Z13A 2IYBA 2I1KA 4F7UP 4DXAB 1U2BA 4GNKB 5IRSA 1T77A 5J3QA 2UZSA 1AQCA 1M7EA 2K00A 2R09A 4NY0A 1U29A 1U5FA 4CYEA 3WYFB 3M1IB 2DX5A 2K8EA 3PP2A 2W2WA 4EJNA 2RVBB 2UZRA 3A8QA 4F7HA 2Z4DA 3PVWA 3FM8C 3P7ZA 2J59M 2LKOA 5M4YB 3KRWA 2K49A 4YONA 4WJ7A 5KCVA 1BTKA 2RSGA 1SHCA 4K81A 1LB1A 4IOYX 1BWNA 5C6RA 1QQGA 1ZYIA 4WSFA 2HE7A 5HE1A 3HQCA 5D27A 2COFA 2V76A 1J0WA 2KUQA 1UPRA 1UEFA 3NWFA 2X18A 2GJYA 1MAIA 3OHMB 2Z0QA 2LG1A 2KGXB 3U7DA 3ZVRA 1W1GA 2GCJA 4H8SA 1KZ7A 4GMXB 2ADZA 1U27A 3NSUA 4TKNA 1P3RA 1W1HA 2NMBA 3ODWA 1LW3A 4IFSA 3FSSA 4HB2B 4DX90 3T06A 1X1GA 2COAA 5L81A 1MK9B 2H7DA 2RUKB 2QKLA 4PQ0A 1OY2A 1FAOA 2RRFA 3KY9A 2KR0A 4HB3B 5DIFB 5LONB 1SGHA 3N7CA 1FHXA 2FJLA 3ML4A 5D3VA 2CRFA 1N3HA 2DKPA 2I5CA 3VIAA 4Y94A 1MKEA 1Y5OA 2YRYA 4KHBA 2LYDA 3PSCA 4EMOA 2AL6A 1TXDA 3VOQA 3BJIA 4K2PA 2COCA 2MFQA 2D9YA 3AU4A 2W2XD 2NBVA 2XQNM 2Y8FA 1I7AA 2DX1A 2DN6A 3F0WA 1X1FA 1U5EA 3G9WA 1EF1A 1UPQA 5CLQB 4HDQA 2D10A 1XR0B 5C16A 1W1DA 3MDBC 2J0JA 2RLOA 2UVMA 4A6HA 3UZTA 1B55A 3PG7A 1V88A 2KCJA 5I2SA 2OQBA 4GPTB 1WI1A 1E5WA 5DHAB 3A8PA 3TVVA 5C5BA 5D3YA 2K2JA 1RRPB 2ZKMX 3O96A 4L6EA 2CAYA 4IAPA 5D3XA 4GOUA 3PZDA 2ZPYA 2KIEA 5C5BB 3HK0A 4D0NB 2DYQA 3HIEA 2H7EA 1XX0A 3SNHA 3SV1A 1PFJA 1V5MA 3NW8A
chains in the Genus database with same CATH topology
2EC1A 2DHJA 1I2HA 1V5PA 2P8VA 3AU5A 1DBHA 5HE0A 5JHHA 5LOPB 2LOXA 2W2XC 5J3YA 3U8ZA 1OQNA 3SYXA 4HB4B 2D11A 1Q67A 2RGNB 2D9VA 1NTVA 1EAZA 5JHGA 4HHVA 1XODA 2D4QA 3GYOA 3FEHA 1XCGA 5D3WA 2YS3A 3ODOA 4HAVB 2BCJA 4CHJA 3D8EA 3OANA 4CHMA 3ZDTA 1EVHA 4HAUB 2AEHA 3X23A 2D2QA 3P6AA 2EMSA 3AJ4A 4ZRIA 5GOWB 3TO1A 1MIZB 1H10A 5J3TA 4BBKA 4MY6A 2CY5A 2LULA 2JP2A 2ELBA 2E2XA 3ODXA 1K5DB 2Z0PA 4GN1A 1WVHA 3BINA 5FI0A 4ZRKA 4GMVA 1WG7A 3CXBB 4F7GA 1GC7A 3GYPA 2LOZA 5HE3A 4A6FA 1UNPA 1UNQA 4HB0B 3PVUA 2J0MA 1KZGA 3SUZA 4A6FB 1ISNA 1M7RA 1U5DA 2I5FA 4KHBB 4HAWB 4EKUA 5DH9B 2MWNB 1MPHA 5DI9B 3TW1A 5HE2A 3CIKA 4KAXB 2QKMA 1UNRA 1ZVRA 1TQZA 4TYZA 1Z87A 5C79A 3WA0A 1ZC4B 2N0YA 1BTNA 5FI1A 2DLWA 2ROZB 1V89A 4HAYB 4DBBA 2DHIA 4YL8A 5JP4A 4KVGB 1DROA 3KRXA 2YVCA 1FHWA 1J19A 1WJMA 1FGYA 2MKRA 2D9WA 2DFKA 4WVFB 2VRWB 1PMSA 4B6HA 1AWEA 1MIXA 3QBVB 1DDMA 1XD4A 1FGZA 1P5TA 2KUPA 1FHOA 4HDOA 2P0DA 2VKIA 2CODA 5JLJB 2PZ1A 1X11A 2IFSA 3V5WA 2YS5A 1WGUA 4KHAA 4XWXA 3DXDA 2D9ZA 2M38A 4C0AA 5CLLB 4HATB 2DHKA 3KSYA 2YT1A 1NU2A 2G35A 1X86A 3HW2B 1RJ2A 1FB8A 1IRSA 2P0HA 2YS1A 1WGQA 4MT7A 1XKEA 4Z2NA 1TJ6A 3ULBA 3PVLA 4P7IA 4PNKA 1PLSA 1X05A 4A5KA 1QC6A 4GXBA 2Y7BA 2ELAA 3D8DA 3MPXA 4K2OA 2OTXA 1NTYA 2DA0A 2GS0A 3QIJA 1K5GB 3SO6A 1BAKA 2MDXA 1ZC3B 2EJ8A 2Z0OA 1ZSQA 2YT0A 3TFMA 2L1CA 2R0DA 4ZRJA 1DDVA 1OMWA 5EFXA 2Y8GA 1GC6A 4Z2MB 2YF0A 2D9XA 2EMTA 2VSZA 4K17A 3PEGA 3F5RA 2I1JA 2DKQA 4HAZB 3KZ1A 1V61A 2CY4A 4A6KA 2GCLA 1DYNA 1PFJA 1NI2A 2L2IA 1EGXA 4GZUA 1V5UA 3IVFA 4HAXB 2RNRB 3D8FA 3A98B 1KI1B 2YSZA 1WJ1A 2J0KA 4DX8A 3TCAA 5KQ1A 2K2UA 3QWMA 2DYNA 4MK0A 4KHOA 1GG3A 1MK7B 2P0FA 2DTCA 2Q13A 2N23A 1Y19B 1ZM0A 3DXCA 2NZ8B 2M14A 3ULCA 5DHFB 5KQ4A 3LJUX 1P6SA 2HTHB 1DDWA 1U5GA 2ROVA 4NSWA 3RCPA 1FOEA 3DXEA 1H4RA 2IYBA 2I1KA 4F7UP 4DXAB 1U2BA 5J3QA 2UZSA 1AQCA 1M7EA 2K00A 2R09A 4NY0A 1U29A 1U5FA 4CYEA 3WYFB 3M1IB 2DX5A 3PP2A 2W2WA 4EJNA 2RVBB 2UZRA 3A8QA 4F7HA 3PVWA 3FM8C 3P7ZA 2J59M 2LKOA 3KRWA 4YONA 4WJ7A 5KCVA 1BTKA 2RSGA 1SHCA 4K81A 1LB1A 4IOYX 1BWNA 5C6RA 1QQGA 4WSFA 2HE7A 5HE1A 3HQCA 5D27A 2COFA 2V76A 1J0WA 1UPRA 1UEFA 2X18A 2GJYA 1MAIA 2Z0QA 2LG1A 2KGXB 3U7DA 3ZVRA 1W1GA 2GCJA 4H8SA 1KZ7A 4GMXB 2ADZA 1U27A 4TKNA 1P3RA 1W1HA 2NMBA 3ODWA 1LW3A 4IFSA 3FSSA 4HB2B 4DX90 3T06A 1X1GA 2COAA 5L81A 1MK9B 2H7DA 2RUKB 2QKLA 4PQ0A 1OY2A 1FAOA 3KY9A 4HB3B 5DIFB 5LONB 1SGHA 3N7CA 1FHXA 2FJLA 3ML4A 5D3VA 2CRFA 1N3HA 2DKPA 2I5CA 3VIAA 4Y94A 1MKEA 1Y5OA 2YRYA 2LYDA 3PSCA 4EMOA 2AL6A 1TXDA 3VOQA 3BJIA 4K2PA 2COCA 2MFQA 2D9YA 2W2XD 3AU4A 2XQNM 2Y8FA 1I7AA 2DX1A 2DN6A 3F0WA 1X1FA 1U5EA 3G9WA 1EF1A 1UPQA 5CLQB 4HDQA 2D10A 1XR0B 5C16A 1W1DA 3MDBC 2J0JA 2RLOA 2UVMA 4A6HA 3UZTA 1B55A 3PG7A 1V88A 2KCJA 2OQBA 4GPTB 1WI1A 1E5WA 5DHAB 3A8PA 3TVVA 5C5BA 5D3YA 2K2JA 1RRPB 3O96A 4L6EA 2CAYA 4IAPA 5D3XA 3PZDA 2ZPYA 5C5BB 3HK0A 4D0NB 2DYQA 2H7EA 1XX0A 3SNHA 3SV1A 3NSUA 1V5MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EC1 A;  2DHJ A;  1I2H A;  1V5P A;  2P8V A;  3AU5 A;  1DBH A;  5HE0 A;  5JHH A;  5LOP B;  2LOX A;  2W2X C;  5J3Y A;  3U8Z A;  1OQN A;  3SYX A;  4HB4 B;  2D11 A;  1Q67 A;  2RGN B;  2D9V A;  1NTV A;  1EAZ A;  5JHG A;  4HHV A;  1XOD A;  2D4Q A;  3GYO A;  3FEH A;  1XCG A;  5D3W A;  2YS3 A;  3ODO A;  4HAV B;  2BCJ A;  4CHJ A;  3D8E A;  3OAN A;  4CHM A;  3ZDT A;  1EVH A;  4HAU B;  2AEH A;  3X23 A;  2D2Q A;  3P6A A;  2EMS A;  3AJ4 A;  4ZRI A;  5GOW B;  3TO1 A;  1MIZ B;  1H10 A;  5J3T A;  4BBK A;  4MY6 A;  2CY5 A;  2LUL A;  2JP2 A;  2ELB A;  2E2X A;  3ODX A;  1K5D B;  2Z0P A;  4GN1 A;  1WVH A;  3BIN A;  5FI0 A;  4ZRK A;  4GMV A;  1WG7 A;  3CXB B;  4F7G A;  1GC7 A;  3GYP A;  2LOZ A;  5HE3 A;  4A6F A;  1UNP A;  1UNQ A;  4HB0 B;  3PVU A;  2J0M A;  1KZG A;  3SUZ A;  4A6F B;  1ISN A;  1M7R A;  1U5D A;  2I5F A;  4KHB B;  4HAW B;  4EKU A;  5DH9 B;  2MWN B;  1MPH A;  5DI9 B;  3TW1 A;  5HE2 A;  3CIK A;  4KAX B;  2QKM A;  1UNR A;  1ZVR A;  1TQZ A;  4TYZ A;  1Z87 A;  5C79 A;  3WA0 A;  1ZC4 B;  2N0Y A;  1BTN A;  5FI1 A;  2DLW A;  2ROZ B;  1V89 A;  4HAY B;  4DBB A;  2DHI A;  4YL8 A;  5JP4 A;  4KVG B;  1DRO A;  3KRX A;  2YVC A;  1FHW A;  1J19 A;  1WJM A;  1FGY A;  2MKR A;  2D9W A;  2DFK A;  4WVF B;  2VRW B;  1PMS A;  4B6H A;  1AWE A;  1MIX A;  3QBV B;  1DDM A;  1XD4 A;  1FGZ A;  1P5T A;  2KUP A;  1FHO A;  4HDO A;  2P0D A;  2VKI A;  2COD A;  5JLJ B;  2PZ1 A;  1X11 A;  2IFS A;  3V5W A;  2YS5 A;  1WGU A;  4KHA A;  4XWX A;  3DXD A;  2D9Z A;  2M38 A;  4C0A A;  5CLL B;  4HAT B;  2DHK A;  3KSY A;  2YT1 A;  1NU2 A;  2G35 A;  1X86 A;  3HW2 B;  1RJ2 A;  1FB8 A;  1IRS A;  2P0H A;  2YS1 A;  1WGQ A;  4MT7 A;  1XKE A;  4Z2N A;  1TJ6 A;  3ULB A;  3PVL A;  4P7I A;  4PNK A;  1PLS A;  1X05 A;  4A5K A;  1QC6 A;  4GXB A;  2Y7B A;  2ELA A;  3D8D A;  3MPX A;  4K2O A;  2OTX A;  1NTY A;  2DA0 A;  2GS0 A;  3QIJ A;  1K5G B;  3SO6 A;  1BAK A;  2MDX A;  1ZC3 B;  2EJ8 A;  2Z0O A;  1ZSQ A;  2YT0 A;  3TFM A;  2L1C A;  2R0D A;  4ZRJ A;  1DDV A;  1OMW A;  5EFX A;  2Y8G A;  1GC6 A;  4Z2M B;  2YF0 A;  2D9X A;  2EMT A;  2VSZ A;  4K17 A;  3PEG A;  3F5R A;  2I1J A;  2DKQ A;  4HAZ B;  3KZ1 A;  1V61 A;  2CY4 A;  4A6K A;  2GCL A;  1DYN A;  1PFJ A;  1NI2 A;  2L2I A;  1EGX A;  4GZU A;  1V5U A;  3IVF A;  4HAX B;  2RNR B;  3D8F A;  3A98 B;  1KI1 B;  2YSZ A;  1WJ1 A;  2J0K A;  4DX8 A;  3TCA A;  5KQ1 A;  2K2U A;  3QWM A;  2DYN A;  4MK0 A;  4KHO A;  1GG3 A;  1MK7 B;  2P0F A;  2DTC A;  2Q13 A;  2N23 A;  1Y19 B;  1ZM0 A;  3DXC A;  2NZ8 B;  2M14 A;  3ULC A;  5DHF B;  5KQ4 A;  3LJU X;  1P6S A;  2HTH B;  1DDW A;  1U5G A;  2ROV A;  4NSW A;  3RCP A;  1FOE A;  3DXE A;  1H4R A;  2IYB A;  2I1K A;  4F7U P;  4DXA B;  1U2B A;  5J3Q A;  2UZS A;  1AQC A;  1M7E A;  2K00 A;  2R09 A;  4NY0 A;  1U29 A;  1U5F A;  4CYE A;  3WYF B;  3M1I B;  2DX5 A;  3PP2 A;  2W2W A;  4EJN A;  2RVB B;  2UZR A;  3A8Q A;  4F7H A;  3PVW A;  3FM8 C;  3P7Z A;  2J59 M;  2LKO A;  3KRW A;  4YON A;  4WJ7 A;  5KCV A;  1BTK A;  2RSG A;  1SHC A;  4K81 A;  1LB1 A;  4IOY X;  1BWN A;  5C6R A;  1QQG A;  4WSF A;  2HE7 A;  5HE1 A;  3HQC A;  5D27 A;  2COF A;  2V76 A;  1J0W A;  1UPR A;  1UEF A;  2X18 A;  2GJY A;  1MAI A;  2Z0Q A;  2LG1 A;  2KGX B;  3U7D A;  3ZVR A;  1W1G A;  2GCJ A;  4H8S A;  1KZ7 A;  4GMX B;  2ADZ A;  1U27 A;  4TKN A;  1P3R A;  1W1H A;  2NMB A;  3ODW A;  1LW3 A;  4IFS A;  3FSS A;  4HB2 B;  4DX9 0;  3T06 A;  1X1G A;  2COA A;  5L81 A;  1MK9 B;  2H7D A;  2RUK B;  2QKL A;  4PQ0 A;  1OY2 A;  1FAO A;  3KY9 A;  4HB3 B;  5DIF B;  5LON B;  1SGH A;  3N7C A;  1FHX A;  2FJL A;  3ML4 A;  5D3V A;  2CRF A;  1N3H A;  2DKP A;  2I5C A;  3VIA A;  4Y94 A;  1MKE A;  1Y5O A;  2YRY A;  2LYD A;  3PSC A;  4EMO A;  2AL6 A;  1TXD A;  3VOQ A;  3BJI A;  4K2P A;  2COC A;  2MFQ A;  2D9Y A;  2W2X D;  3AU4 A;  2XQN M;  2Y8F A;  1I7A A;  2DX1 A;  2DN6 A;  3F0W A;  1X1F A;  1U5E A;  3G9W A;  1EF1 A;  1UPQ A;  5CLQ B;  4HDQ A;  2D10 A;  1XR0 B;  5C16 A;  1W1D A;  3MDB C;  2J0J A;  2RLO A;  2UVM A;  4A6H A;  3UZT A;  1B55 A;  3PG7 A;  1V88 A;  2KCJ A;  2OQB A;  4GPT B;  1WI1 A;  1E5W A;  5DHA B;  3A8P A;  3TVV A;  5C5B A;  5D3Y A;  2K2J A;  1RRP B;  3O96 A;  4L6E A;  2CAY A;  4IAP A;  5D3X A;  3PZD A;  2ZPY A;  5C5B B;  3HK0 A;  4D0N B;  2DYQ A;  2H7E A;  1XX0 A;  3SNH A;  3SV1 A;  3NSU A;  1V5M A; 
#chains in the Genus database with same CATH topology
 2EC1 A;  2DHJ A;  1I2H A;  1V5P A;  2P8V A;  3AU5 A;  1DBH A;  5HE0 A;  5JHH A;  5LOP B;  2LOX A;  2W2X C;  5J3Y A;  3U8Z A;  1OQN A;  3SYX A;  4HB4 B;  2D11 A;  1Q67 A;  2RGN B;  2D9V A;  1NTV A;  1EAZ A;  5JHG A;  4HHV A;  1XOD A;  2D4Q A;  3GYO A;  3FEH A;  2Z14 A;  1XCG A;  5D3W A;  2YS3 A;  3ODO A;  4HAV B;  2BCJ A;  4CHJ A;  3DCX A;  3D8E A;  3OAN A;  4CHM A;  3ZDT A;  1EVH A;  4HAU B;  2AEH A;  3X23 A;  2D2Q A;  3P6A A;  2EMS A;  3AJ4 A;  4ZRI A;  5GOW B;  3TO1 A;  1MIZ B;  1H10 A;  5J3T A;  4BBK A;  4MY6 A;  2CY5 A;  2LUL A;  2JP2 A;  2ELB A;  2E2X A;  3ODX A;  1K5D B;  2Z0P A;  4GN1 A;  1WVH A;  3BIN A;  5FI0 A;  4ZRK A;  4L1R A;  4GMV A;  1WG7 A;  3CXB B;  4F7G A;  4OSN A;  1GC7 A;  3GYP A;  2LOZ A;  4OT1 A;  5HE3 A;  4A6F A;  1UNP A;  4QXA B;  1UNQ A;  4HB0 B;  3PVU A;  5LG4 B;  2J0M A;  3HSA A;  1KZG A;  2FJU B;  3SUZ A;  4A6F B;  1ISN A;  1M7R A;  1U5D A;  2I5F A;  4QJ4 B;  4KHB B;  4HAW B;  4EKU A;  3A58 A;  5DH9 B;  2MWN B;  1MPH A;  5DI9 B;  3U12 A;  3TW1 A;  3B77 A;  5HE2 A;  3CIK A;  4QJ3 B;  4KAX B;  2QKM A;  1UNR A;  1ZVR A;  1TQZ A;  4TYZ A;  1Z87 A;  5C79 A;  3WA0 A;  1ZC4 B;  2N0Y A;  1BTN A;  4QJ5 B;  5FI1 A;  2DLW A;  2ROZ B;  1V89 A;  4HAY B;  4DBB A;  2DHI A;  4YL8 A;  5JP4 A;  4KVG B;  1DRO A;  3KRX A;  2YVC A;  1FHW A;  4HSI A;  1J19 A;  1WJM A;  1FGY A;  2MKR A;  2D9W A;  2DFK A;  4WVF B;  5I2M A;  2VRW B;  1PMS A;  4B6H A;  1AWE A;  1MIX A;  3QBV B;  1DDM A;  1XD4 A;  1FGZ A;  1P5T A;  2KUP A;  1FHO A;  4HDO A;  2P0D A;  2VKI A;  2COD A;  5JLJ B;  2PZ1 A;  1X11 A;  2IFS A;  3V5W A;  2YS5 A;  1WGU A;  4KHA A;  4XWX A;  3DXD A;  2D9Z A;  2M38 A;  4C0A A;  5CLL B;  4HAT B;  2DHK A;  3KSY A;  2YT1 A;  2R2Y A;  1NU2 A;  2G35 A;  1X86 A;  3HW2 B;  1RJ2 A;  1FB8 A;  1IRS A;  2Z59 A;  2P0H A;  2YS1 A;  1WGQ A;  4MT7 A;  1XKE A;  4Z2N A;  1TJ6 A;  3ULB A;  3PVL A;  4P7I A;  4PNK A;  1PLS A;  1X05 A;  4A5K A;  1QC6 A;  4GXB A;  2Y7B A;  2ELA A;  3D8D A;  3MPX A;  3NWD A;  4K2O A;  2OTX A;  1NTY A;  2DA0 A;  2GS0 A;  3QIJ A;  1K5G B;  3SO6 A;  1BAK A;  2KIG A;  2MDX A;  1ZC3 B;  2EJ8 A;  2YT2 A;  2Z0O A;  4DIX A;  1ZSQ A;  2YT0 A;  3TFM A;  2L1C A;  2R0D A;  4ZRJ A;  1DDV A;  1OMW A;  5EFX A;  2Y8G A;  4CSQ A;  1GC6 A;  4Z2M B;  3FVC A;  4D6W A;  2YF0 A;  1MI1 A;  2D9X A;  2EMT A;  2VSZ A;  4K17 A;  3PEG A;  3F5R A;  2I1J A;  2DKQ A;  4HAZ B;  3KZ1 A;  1V61 A;  2CY4 A;  4A6K A;  2GCL A;  1DYN A;  3NWA A;  1NI2 A;  2L2I A;  1EGX A;  4GZU A;  1V5U A;  3IVF A;  4HAX B;  2RNR B;  3D8F A;  3A98 B;  1KI1 B;  2YSZ A;  1WJ1 A;  2J0K A;  4DX8 A;  3TCA A;  5KQ1 A;  2K2U A;  3QWM A;  2DYN A;  4MK0 A;  4KHO A;  1GG3 A;  1MK7 B;  2P0F A;  2DTC A;  2Q13 A;  2N23 A;  1Y19 B;  1ZM0 A;  3DXC A;  2NZ8 B;  2M14 A;  2GUM A;  3ULC A;  5DHF B;  5KQ4 A;  3LJU X;  1P6S A;  2HTH B;  1DDW A;  1U5G A;  2ROV A;  4NSW A;  3RCP A;  1FOE A;  3DXE A;  1H4R A;  2Z13 A;  2IYB A;  2I1K A;  4F7U P;  4DXA B;  1U2B A;  4GNK B;  5IRS A;  1T77 A;  5J3Q A;  2UZS A;  1AQC A;  1M7E A;  2K00 A;  2R09 A;  4NY0 A;  1U29 A;  1U5F A;  4CYE A;  3WYF B;  3M1I B;  2DX5 A;  2K8E A;  3PP2 A;  2W2W A;  4EJN A;  2RVB B;  2UZR A;  3A8Q A;  4F7H A;  2Z4D A;  3PVW A;  3FM8 C;  3P7Z A;  2J59 M;  2LKO A;  5M4Y B;  3KRW A;  2K49 A;  4YON A;  4WJ7 A;  5KCV A;  1BTK A;  2RSG A;  1SHC A;  4K81 A;  1LB1 A;  4IOY X;  1BWN A;  5C6R A;  1QQG A;  1ZYI A;  4WSF A;  2HE7 A;  5HE1 A;  3HQC A;  5D27 A;  2COF A;  2V76 A;  1J0W A;  2KUQ A;  1UPR A;  1UEF A;  3NWF A;  2X18 A;  2GJY A;  1MAI A;  3OHM B;  2Z0Q A;  2LG1 A;  2KGX B;  3U7D A;  3ZVR A;  1W1G A;  2GCJ A;  4H8S A;  1KZ7 A;  4GMX B;  2ADZ A;  1U27 A;  3NSU A;  4TKN A;  1P3R A;  1W1H A;  2NMB A;  3ODW A;  1LW3 A;  4IFS A;  3FSS A;  4HB2 B;  4DX9 0;  3T06 A;  1X1G A;  2COA A;  5L81 A;  1MK9 B;  2H7D A;  2RUK B;  2QKL A;  4PQ0 A;  1OY2 A;  1FAO A;  2RRF A;  3KY9 A;  2KR0 A;  4HB3 B;  5DIF B;  5LON B;  1SGH A;  3N7C A;  1FHX A;  2FJL A;  3ML4 A;  5D3V A;  2CRF A;  1N3H A;  2DKP A;  2I5C A;  3VIA A;  4Y94 A;  1MKE A;  1Y5O A;  2YRY A;  4KHB A;  2LYD A;  3PSC A;  4EMO A;  2AL6 A;  1TXD A;  3VOQ A;  3BJI A;  4K2P A;  2COC A;  2MFQ A;  2D9Y A;  3AU4 A;  2W2X D;  2NBV A;  2XQN M;  2Y8F A;  1I7A A;  2DX1 A;  2DN6 A;  3F0W A;  1X1F A;  1U5E A;  3G9W A;  1EF1 A;  1UPQ A;  5CLQ B;  4HDQ A;  2D10 A;  1XR0 B;  5C16 A;  1W1D A;  3MDB C;  2J0J A;  2RLO A;  2UVM A;  4A6H A;  3UZT A;  1B55 A;  3PG7 A;  1V88 A;  2KCJ A;  5I2S A;  2OQB A;  4GPT B;  1WI1 A;  1E5W A;  5DHA B;  3A8P A;  3TVV A;  5C5B A;  5D3Y A;  2K2J A;  1RRP B;  2ZKM X;  3O96 A;  4L6E A;  2CAY A;  4IAP A;  5D3X A;  4GOU A;  3PZD A;  2ZPY A;  2KIE A;  5C5B B;  3HK0 A;  4D0N B;  2DYQ A;  3HIE A;  2H7E A;  1XX0 A;  3SNH A;  3SV1 A;  1PFJ A;  1V5M A;  3NW8 A; 
#chains in the Genus database with same CATH homology
 2EC1 A;  2DHJ A;  1I2H A;  1V5P A;  2P8V A;  3AU5 A;  1DBH A;  5HE0 A;  5JHH A;  5LOP B;  2LOX A;  2W2X C;  5J3Y A;  3U8Z A;  1OQN A;  3SYX A;  4HB4 B;  2D11 A;  1Q67 A;  2RGN B;  2D9V A;  1NTV A;  1EAZ A;  5JHG A;  4HHV A;  1XOD A;  2D4Q A;  3GYO A;  3FEH A;  1XCG A;  5D3W A;  2YS3 A;  3ODO A;  4HAV B;  2BCJ A;  4CHJ A;  3D8E A;  3OAN A;  4CHM A;  3ZDT A;  1EVH A;  4HAU B;  2AEH A;  3X23 A;  2D2Q A;  3P6A A;  2EMS A;  3AJ4 A;  4ZRI A;  5GOW B;  3TO1 A;  1MIZ B;  1H10 A;  5J3T A;  4BBK A;  4MY6 A;  2CY5 A;  2LUL A;  2JP2 A;  2ELB A;  2E2X A;  3ODX A;  1K5D B;  2Z0P A;  4GN1 A;  1WVH A;  3BIN A;  5FI0 A;  4ZRK A;  4GMV A;  1WG7 A;  3CXB B;  4F7G A;  1GC7 A;  3GYP A;  2LOZ A;  5HE3 A;  4A6F A;  1UNP A;  1UNQ A;  4HB0 B;  3PVU A;  2J0M A;  1KZG A;  3SUZ A;  4A6F B;  1ISN A;  1M7R A;  1U5D A;  2I5F A;  4KHB B;  4HAW B;  4EKU A;  5DH9 B;  2MWN B;  1MPH A;  5DI9 B;  3TW1 A;  5HE2 A;  3CIK A;  4KAX B;  2QKM A;  1UNR A;  1ZVR A;  1TQZ A;  4TYZ A;  1Z87 A;  5C79 A;  3WA0 A;  1ZC4 B;  2N0Y A;  1BTN A;  5FI1 A;  2DLW A;  2ROZ B;  1V89 A;  4HAY B;  4DBB A;  2DHI A;  4YL8 A;  5JP4 A;  4KVG B;  1DRO A;  3KRX A;  2YVC A;  1FHW A;  1J19 A;  1WJM A;  1FGY A;  2MKR A;  2D9W A;  2DFK A;  4WVF B;  2VRW B;  1PMS A;  4B6H A;  1AWE A;  1MIX A;  3QBV B;  1DDM A;  1XD4 A;  1FGZ A;  1P5T A;  2KUP A;  1FHO A;  4HDO A;  2P0D A;  2VKI A;  2COD A;  5JLJ B;  2PZ1 A;  1X11 A;  2IFS A;  3V5W A;  2YS5 A;  1WGU A;  4KHA A;  4XWX A;  3DXD A;  2D9Z A;  2M38 A;  4C0A A;  5CLL B;  4HAT B;  2DHK A;  3KSY A;  2YT1 A;  1NU2 A;  2G35 A;  1X86 A;  3HW2 B;  1RJ2 A;  1FB8 A;  1IRS A;  2P0H A;  2YS1 A;  1WGQ A;  4MT7 A;  1XKE A;  4Z2N A;  1TJ6 A;  3ULB A;  3PVL A;  4P7I A;  4PNK A;  1PLS A;  1X05 A;  4A5K A;  1QC6 A;  4GXB A;  2Y7B A;  2ELA A;  3D8D A;  3MPX A;  4K2O A;  2OTX A;  1NTY A;  2DA0 A;  2GS0 A;  3QIJ A;  1K5G B;  3SO6 A;  1BAK A;  2MDX A;  1ZC3 B;  2EJ8 A;  2Z0O A;  1ZSQ A;  2YT0 A;  3TFM A;  2L1C A;  2R0D A;  4ZRJ A;  1DDV A;  1OMW A;  5EFX A;  2Y8G A;  1GC6 A;  4Z2M B;  2YF0 A;  2D9X A;  2EMT A;  2VSZ A;  4K17 A;  3PEG A;  3F5R A;  2I1J A;  2DKQ A;  4HAZ B;  3KZ1 A;  1V61 A;  2CY4 A;  4A6K A;  2GCL A;  1DYN A;  1PFJ A;  1NI2 A;  2L2I A;  1EGX A;  4GZU A;  1V5U A;  3IVF A;  4HAX B;  2RNR B;  3D8F A;  3A98 B;  1KI1 B;  2YSZ A;  1WJ1 A;  2J0K A;  4DX8 A;  3TCA A;  5KQ1 A;  2K2U A;  3QWM A;  2DYN A;  4MK0 A;  4KHO A;  1GG3 A;  1MK7 B;  2P0F A;  2DTC A;  2Q13 A;  2N23 A;  1Y19 B;  1ZM0 A;  3DXC A;  2NZ8 B;  2M14 A;  3ULC A;  5DHF B;  5KQ4 A;  3LJU X;  1P6S A;  2HTH B;  1DDW A;  1U5G A;  2ROV A;  4NSW A;  3RCP A;  1FOE A;  3DXE A;  1H4R A;  2IYB A;  2I1K A;  4F7U P;  4DXA B;  1U2B A;  5J3Q A;  2UZS A;  1AQC A;  1M7E A;  2K00 A;  2R09 A;  4NY0 A;  1U29 A;  1U5F A;  4CYE A;  3WYF B;  3M1I B;  2DX5 A;  3PP2 A;  2W2W A;  4EJN A;  2RVB B;  2UZR A;  3A8Q A;  4F7H A;  3PVW A;  3FM8 C;  3P7Z A;  2J59 M;  2LKO A;  3KRW A;  4YON A;  4WJ7 A;  5KCV A;  1BTK A;  2RSG A;  1SHC A;  4K81 A;  1LB1 A;  4IOY X;  1BWN A;  5C6R A;  1QQG A;  4WSF A;  2HE7 A;  5HE1 A;  3HQC A;  5D27 A;  2COF A;  2V76 A;  1J0W A;  1UPR A;  1UEF A;  2X18 A;  2GJY A;  1MAI A;  2Z0Q A;  2LG1 A;  2KGX B;  3U7D A;  3ZVR A;  1W1G A;  2GCJ A;  4H8S A;  1KZ7 A;  4GMX B;  2ADZ A;  1U27 A;  4TKN A;  1P3R A;  1W1H A;  2NMB A;  3ODW A;  1LW3 A;  4IFS A;  3FSS A;  4HB2 B;  4DX9 0;  3T06 A;  1X1G A;  2COA A;  5L81 A;  1MK9 B;  2H7D A;  2RUK B;  2QKL A;  4PQ0 A;  1OY2 A;  1FAO A;  3KY9 A;  4HB3 B;  5DIF B;  5LON B;  1SGH A;  3N7C A;  1FHX A;  2FJL A;  3ML4 A;  5D3V A;  2CRF A;  1N3H A;  2DKP A;  2I5C A;  3VIA A;  4Y94 A;  1MKE A;  1Y5O A;  2YRY A;  2LYD A;  3PSC A;  4EMO A;  2AL6 A;  1TXD A;  3VOQ A;  3BJI A;  4K2P A;  2COC A;  2MFQ A;  2D9Y A;  2W2X D;  3AU4 A;  2XQN M;  2Y8F A;  1I7A A;  2DX1 A;  2DN6 A;  3F0W A;  1X1F A;  1U5E A;  3G9W A;  1EF1 A;  1UPQ A;  5CLQ B;  4HDQ A;  2D10 A;  1XR0 B;  5C16 A;  1W1D A;  3MDB C;  2J0J A;  2RLO A;  2UVM A;  4A6H A;  3UZT A;  1B55 A;  3PG7 A;  1V88 A;  2KCJ A;  2OQB A;  4GPT B;  1WI1 A;  1E5W A;  5DHA B;  3A8P A;  3TVV A;  5C5B A;  5D3Y A;  2K2J A;  1RRP B;  3O96 A;  4L6E A;  2CAY A;  4IAP A;  5D3X A;  3PZD A;  2ZPY A;  5C5B B;  3HK0 A;  4D0N B;  2DYQ A;  2H7E A;  1XX0 A;  3SNH A;  3SV1 A;  3NSU A;  1V5M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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