3D8EA

Crystal structure of the human fe65-ptb1 domain (trigonal crystal form)
Total Genus 28

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
140
structure length
123
Chain Sequence
KCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYKDLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGDSGRERDFAYVARDKLTQMLKCHVFRCEAPAKNIATSLHEICSKIMAELE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the human Fe65-PTB1 domain.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Amyloid beta A4 precursor protein-binding family B member 1
total genus 28
structure length 123
sequence length 140
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2008-05-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 3d8eA00
2VSZA 1WJ1A 3SNHA 2H7DA 1NI2A 1BAKA 1DDWA 1N3HA 1MIZB 2RGNB 2RLOA 4HAVB 2AL6A 3UZTA 4NSWA 4TKNA 5DHFB 1V88A 2QKLA 3ODOA 5C16A 3PP2A 4HAXB 1TQZA 1WGQA 2NMBA 3VOQA 2D4QA 1MIXA 3FM8C 1KZ7A 5JP4A 1SGHA 3SYXA 4XWXA 2DN6A 4F7GA 2DX5A 4GN1A 3ML4A 2UVMA 2KGXB 2D9YA 5DH9B 2OQBA 5KQ1A 4MY6A 5KQ4A 4HB4B 3PVWA 4PNKA 4GMVA 4HB2B 2I1JA 3X23A 4A5KA 2RNRB 3T06A 2GS0A 2DKPA 2EJ8A 1V89A 1MKEA 1WJMA 2HE7A 1DBHA 4NY0A 2G35A 4HAWB 5LONB 4A6FA 1ZC4B 2DX1A 3BINA 2COFA 1UEFA 4H8SA 2YSZA 3KZ1A 4K2PA 3OANA 1IRSA 3PVUA 1U5GA 4A6HA 2CRFA 4CHJA 4CYEA 4DX90 2W2XC 1GC6A 4K17A 3TO1A 4DXAB 2D11A 2YS5A 5C5BB 4IOYX 4F7HA 2W2WA 2MWNB 2M14A 2ELAA 3DXDA 3RCPA 4Y94A 1FB8A 3N7CA 1ZSQA 3PSCA 5D3VA 2J0KA 3LJUX 2L2IA 2N0YA 5LOPB 4TYZA 4EJNA 1EAZA 3WA0A 4KHAA 2W2XD 1W1DA 4MT7A 1I7AA 1UNQA 2D9ZA 1FHWA 1V5PA 1PMSA 2VRWB 1WI1A 2PZ1A 1UPQA 1NTVA 3P7ZA 3MPXA 4KHBB 3VIAA 2LG1A 1OMWA 2DYQA 2P0HA 2RUKB 5JHHA 3KRWA 1AQCA 1WGUA 3FSSA 1PLSA 2I5FA 2GJYA 4D0NB 3PVLA 2D10A 2IFSA 1U27A 3HK0A 4K2OA 2K2UA 3SUZA 1P3RA 4EMOA 1V5UA 3O96A 3F5RA 1X86A 2QKMA 3AJ4A 3SV1A 2E2XA 2YS3A 3PEGA 2LYDA 3U8ZA 4WSFA 1I2HA 4IAPA 2D9VA 3ODWA 4BBKA 3A98B 2LKOA 4HAUB 1X05A 3A8QA 4HDQA 1LB1A 2R0DA 4GMXB 5D3WA 4GPTB 4ZRIA 4Z2MB 3ULCA 2I1KA 4IFSA 2GCJA 4HAYB 2GCLA 2ROZB 2Z0QA 2DLWA 1K5GB 3QBVB 2DYNA 2P0DA 2ADZA 5D27A 1Y5OA 4GXBA 1MK7B 4HB0B 2H7EA 5HE2A 3D8EA 4P7IA 4HDOA 1AWEA 4KAXB 5J3TA 2ROVA 2Y8FA 3V5WA 2MDXA 1GC7A 3ULBA 4CHMA 1W1HA 2UZSA 1U5FA 2V76A 2YT0A 2YF0A 2EMSA 1FHXA 2DTCA 1X11A 5DI9B 1V61A 3TFMA 1NTYA 5FI0A 1E5WA 4A6KA 2D2QA 2J59M 2LOZA 1FGZA 2NZ8B 3U7DA 1XX0A 2YS1A 3QIJA 1BWNA 1XCGA 2D9WA 3AU5A 2ZPYA 3GYPA 5C5BA 1TXDA 5D3XA 2K00A 3DXCA 1K5DB 4DBBA 2JP2A 3IVFA 5C79A 5D3YA 1LW3A 2K2JA 5HE0A 5HE1A 2Q13A 1DYNA 4Z2NA 3MDBC 5J3YA 1PFJA 4KVGB 2KUPA 4WJ7A 3G9WA 1X1FA 2R09A 5C6RA 2J0JA 5GOWB 1V5MA 1KI1B 1EGXA 2I5CA 1U5EA 1KZGA 2XQNM 1M7RA 1ZM0A 1RJ2A 5JLJB 2LOXA 2AEHA 4HHVA 1FHOA 4HAZB 1EVHA 1UNPA 2DFKA 3P6AA 1FAOA 1GG3A 1QQGA 2ELBA 2MKRA 3ZDTA 1ISNA 2P0FA 4C0AA 2J0MA 1W1GA 2YRYA 1UNRA 1Z87A 4YONA 3BJIA 5DHAB 3TCAA 1X1GA 3TVVA 3D8DA 1XR0B 3QWMA 2DA0A 2OTXA 1BTKA 3SO6A 2RSGA 2DHKA 4HB3B 1H4RA 2DHJA 4ZRKA 1ZC3B 1OQNA 4HATB 1WG7A 1MAIA 1Y19B 2BCJA 1P6SA 3TW1A 1U29A 1DROA 1M7EA 1J0WA 1SHCA 4A6FB 2Z0OA 1NU2A 4YL8A 5KCVA 2X18A 4GZUA 4K81A 5J3QA 1U5DA 1EF1A 3NSUA 5CLQB 3DXEA 5JHGA 2YVCA 3KSYA 3FEHA 3AU4A 2CY5A 1DDMA 1B55A 3HW2B 2MFQA 2CAYA 3ODXA 1WVHA 2COCA 3M1IB 2HTHB 3PG7A 1ZVRA 5FI1A 2IYBA 3PZDA 4L6EA 2P8VA 2COAA 2RVBB 4F7UP 1DDVA 4MK0A 2Y7BA 2CODA 3GYOA 1XODA 2UZRA 5CLLB 2EMTA 3A8PA 2EC1A 4B6HA 4DX8A 2L1CA 1FGYA 2CY4A 2Y8GA 3KRXA 3WYFB 2KCJA 3D8FA 2DKQA 5DIFB 1XD4A 4ZRJA 1J19A 1MK9B 2Z0PA 3KY9A 1UPRA 1XKEA 1TJ6A 1H10A 1Q67A 3CXBB 5EFXA 1MPHA 2DHIA 2N23A 4KHOA 1RRPB 3F0WA 4WVFB 2YT1A 2LULA 4PQ0A 3CIKA 2FJLA 2VKIA 3HQCA 3ZVRA 1OY2A 4EKUA 1QC6A 2D9XA 5HE3A 1U2BA 1FOEA 1P5TA 1BTNA 2M38A 5L81A
chains in the Genus database with same CATH superfamily
2VSZA 3NW8A 3NWAA 1WJ1A 2Z4DA 3SNHA 2H7DA 2KIEA 1NI2A 1BAKA 2GUMA 1DDWA 1N3HA 1MIZB 2RGNB 2RLOA 4HAVB 2AL6A 3UZTA 4NSWA 4TKNA 5DHFB 4D6WA 1V88A 2NBVA 2QKLA 3ODOA 3HIEA 5C16A 3PP2A 4HAXB 1TQZA 1WGQA 2NMBA 3VOQA 2D4QA 1MIXA 3FM8C 1KZ7A 5JP4A 1SGHA 3SYXA 4XWXA 2DN6A 4F7GA 2DX5A 4GN1A 3ML4A 2UVMA 2KGXB 2D9YA 5DH9B 2OQBA 5KQ1A 4MY6A 5KQ4A 4HB4B 3PVWA 4PNKA 4GMVA 4HB2B 2I1JA 3X23A 4A5KA 2RNRB 3T06A 2GS0A 2DKPA 2EJ8A 4QJ3B 1T77A 1V89A 4HSIA 1MKEA 3NWDA 1WJMA 2HE7A 1DBHA 4QJ5B 4NY0A 4OT1A 2G35A 4HAWB 5LONB 4A6FA 1ZC4B 2K49A 2DX1A 3BINA 2COFA 1UEFA 4H8SA 2YSZA 3KZ1A 4K2PA 3OANA 1IRSA 3PVUA 1U5GA 2Z14A 4A6HA 2CRFA 4CHJA 4CYEA 4DX90 2W2XC 1GC6A 4GOUA 4K17A 3TO1A 4DXAB 2D11A 2YS5A 5C5BB 4IOYX 4F7HA 2W2WA 1MI1A 2MWNB 4QXAB 2M14A 2ELAA 3DXDA 3RCPA 4Y94A 1FB8A 3N7CA 1ZSQA 3PSCA 5D3VA 2J0KA 3LJUX 2KIGA 2L2IA 2N0YA 5LOPB 4TYZA 4EJNA 1EAZA 3WA0A 4KHAA 2W2XD 1W1DA 3OHMB 4MT7A 1I7AA 1UNQA 2D9ZA 1FHWA 1V5PA 1PMSA 2VRWB 4DIXA 1WI1A 5I2SA 2PZ1A 1UPQA 1NTVA 3P7ZA 3MPXA 5LG4B 4KHBB 3VIAA 2LG1A 1OMWA 2KR0A 2DYQA 2P0HA 2RUKB 5JHHA 3KRWA 1AQCA 1WGUA 3FSSA 1PLSA 2I5FA 3A58A 2GJYA 4D0NB 3PVLA 2D10A 2IFSA 1U27A 3HK0A 4K2OA 2K2UA 3SUZA 1P3RA 4EMOA 1V5UA 4L1RA 3O96A 3F5RA 1X86A 2RRFA 2QKMA 3AJ4A 3SV1A 2E2XA 4GNKB 2YS3A 3PEGA 2LYDA 3U8ZA 4WSFA 1I2HA 4IAPA 2D9VA 3ODWA 2FJUB 4BBKA 3A98B 2LKOA 4HAUB 1X05A 3A8QA 4HDQA 1LB1A 2R0DA 4GMXB 5D3WA 4GPTB 4ZRIA 4Z2MB 3ULCA 2I1KA 4IFSA 2GCJA 4HAYB 2GCLA 2ROZB 2Z0QA 2DLWA 1K5GB 3QBVB 2DYNA 2P0DA 2ADZA 5D27A 1Y5OA 4GXBA 5I2MA 1MK7B 4HB0B 2H7EA 5HE2A 3D8EA 4P7IA 4OSNA 4HDOA 1AWEA 4KAXB 5J3TA 2ROVA 2Y8FA 3V5WA 4QJ4B 2MDXA 1GC7A 3ULBA 3U12A 4CHMA 1W1HA 2UZSA 1U5FA 2V76A 2YT0A 2YF0A 2EMSA 1FHXA 2DTCA 1X11A 5DI9B 1V61A 3TFMA 1NTYA 4CSQA 5FI0A 1E5WA 4A6KA 2D2QA 2J59M 2LOZA 1FGZA 2NZ8B 3U7DA 1XX0A 2YS1A 3QIJA 1BWNA 1XCGA 2D9WA 3AU5A 2ZPYA 3GYPA 5C5BA 1TXDA 5D3XA 3B77A 2K00A 3DXCA 3FVCA 1K5DB 4DBBA 2JP2A 3IVFA 5C79A 5D3YA 1LW3A 2K2JA 5HE0A 5HE1A 2Q13A 1DYNA 4Z2NA 3MDBC 5J3YA 1PFJA 4KVGB 2KUPA 4WJ7A 3G9WA 1X1FA 2R09A 5C6RA 2J0JA 5GOWB 1V5MA 1KI1B 1EGXA 2I5CA 1U5EA 4KHBA 1KZGA 2XQNM 1M7RA 1ZM0A 1RJ2A 5JLJB 2LOXA 2AEHA 4HHVA 1FHOA 4HAZB 1EVHA 1UNPA 2DFKA 3P6AA 1FAOA 1GG3A 1QQGA 2ELBA 2MKRA 3NWFA 3ZDTA 1ISNA 2P0FA 4C0AA 2J0MA 3HSAA 1W1GA 2YRYA 1UNRA 2YT2A 1Z87A 4YONA 3BJIA 2KUQA 5DHAB 5IRSA 3TCAA 1X1GA 3TVVA 3D8DA 1XR0B 3QWMA 1ZYIA 2DA0A 2OTXA 1BTKA 3SO6A 2RSGA 2DHKA 2K8EA 3DCXA 4HB3B 1H4RA 2DHJA 4ZRKA 1ZC3B 1OQNA 4HATB 1WG7A 1MAIA 1Y19B 2BCJA 2ZKMX 1P6SA 3TW1A 1U29A 2Z59A 1DROA 1M7EA 2Z13A 1J0WA 1SHCA 4A6FB 2Z0OA 1NU2A 4YL8A 5KCVA 2X18A 4GZUA 4K81A 5J3QA 1U5DA 1EF1A 3NSUA 5CLQB 3DXEA 5JHGA 2YVCA 3KSYA 3FEHA 3AU4A 2CY5A 1DDMA 1B55A 3HW2B 2MFQA 2CAYA 3ODXA 1WVHA 2COCA 3M1IB 2HTHB 3PG7A 1ZVRA 5FI1A 2IYBA 5M4YB 3PZDA 4L6EA 2P8VA 2COAA 2RVBB 4F7UP 1DDVA 4MK0A 2Y7BA 2CODA 3GYOA 1XODA 2UZRA 5CLLB 2EMTA 3A8PA 2EC1A 4B6HA 4DX8A 2L1CA 1FGYA 2CY4A 2Y8GA 3KRXA 3WYFB 2KCJA 3D8FA 2DKQA 5DIFB 1XD4A 4ZRJA 1J19A 1MK9B 2Z0PA 3KY9A 1UPRA 1XKEA 1TJ6A 1H10A 1Q67A 3CXBB 5EFXA 1MPHA 2DHIA 2N23A 4KHOA 2R2YA 1RRPB 3F0WA 4WVFB 2YT1A 2LULA 4PQ0A 3CIKA 2FJLA 2VKIA 3HQCA 3ZVRA 1OY2A 4EKUA 1QC6A 2D9XA 5HE3A 1U2BA 1FOEA 1P5TA 1BTNA 2M38A 5L81A
chains in the Genus database with same CATH topology
2VSZA 1WJ1A 3SNHA 2H7DA 1NI2A 1BAKA 1DDWA 1N3HA 1MIZB 2RGNB 2RLOA 4HAVB 2AL6A 3UZTA 4NSWA 4TKNA 5DHFB 1V88A 2QKLA 3ODOA 5C16A 3PP2A 4HAXB 1TQZA 1WGQA 2NMBA 3VOQA 2D4QA 1MIXA 3FM8C 1KZ7A 5JP4A 1SGHA 3SYXA 4XWXA 2DN6A 4F7GA 2DX5A 4GN1A 3ML4A 2UVMA 2KGXB 2D9YA 5DH9B 2OQBA 5KQ1A 4MY6A 5KQ4A 4HB4B 3PVWA 4PNKA 4GMVA 4HB2B 2I1JA 3X23A 4A5KA 2RNRB 3T06A 2GS0A 2DKPA 2EJ8A 1V89A 1MKEA 1WJMA 2HE7A 1DBHA 4NY0A 2G35A 4HAWB 5LONB 4A6FA 1ZC4B 2DX1A 3BINA 2COFA 1UEFA 4H8SA 2YSZA 3KZ1A 4K2PA 3OANA 1IRSA 3PVUA 1U5GA 4A6HA 2CRFA 4CHJA 4CYEA 4DX90 2W2XC 1GC6A 4K17A 3TO1A 4DXAB 2D11A 2YS5A 5C5BB 4IOYX 4F7HA 2W2WA 2MWNB 2M14A 2ELAA 3DXDA 3RCPA 4Y94A 1FB8A 3N7CA 1ZSQA 3PSCA 5D3VA 2J0KA 3LJUX 2L2IA 2N0YA 5LOPB 4TYZA 4EJNA 1EAZA 3WA0A 4KHAA 2W2XD 1W1DA 4MT7A 1I7AA 1UNQA 2D9ZA 1FHWA 1V5PA 1PMSA 2VRWB 1WI1A 2PZ1A 1UPQA 1NTVA 3P7ZA 3MPXA 4KHBB 3VIAA 2LG1A 1OMWA 2DYQA 2P0HA 2RUKB 5JHHA 3KRWA 1AQCA 1WGUA 3FSSA 1PLSA 2I5FA 2GJYA 4D0NB 3PVLA 2D10A 2IFSA 1U27A 3HK0A 4K2OA 2K2UA 3SUZA 1P3RA 4EMOA 1V5UA 3O96A 3F5RA 1X86A 2QKMA 3AJ4A 3SV1A 2E2XA 2YS3A 3PEGA 2LYDA 3U8ZA 4WSFA 1I2HA 4IAPA 2D9VA 3ODWA 4BBKA 3A98B 2LKOA 4HAUB 1X05A 3A8QA 4HDQA 1LB1A 2R0DA 4GMXB 5D3WA 4GPTB 4ZRIA 4Z2MB 3ULCA 2I1KA 4IFSA 2GCJA 4HAYB 2GCLA 2ROZB 2Z0QA 2DLWA 1K5GB 3QBVB 2DYNA 2P0DA 2ADZA 5D27A 1Y5OA 4GXBA 1MK7B 4HB0B 2H7EA 5HE2A 3D8EA 4P7IA 4HDOA 1AWEA 4KAXB 5J3TA 2ROVA 2Y8FA 3V5WA 2MDXA 1GC7A 3ULBA 4CHMA 1W1HA 2UZSA 1U5FA 2V76A 2YT0A 2YF0A 2EMSA 1FHXA 2DTCA 1X11A 5DI9B 1V61A 3TFMA 1NTYA 5FI0A 1E5WA 4A6KA 2D2QA 2J59M 2LOZA 1FGZA 2NZ8B 3U7DA 1XX0A 2YS1A 3QIJA 1BWNA 1XCGA 2D9WA 3AU5A 2ZPYA 3GYPA 5C5BA 1TXDA 5D3XA 2K00A 3DXCA 1K5DB 4DBBA 2JP2A 3IVFA 5C79A 5D3YA 1LW3A 2K2JA 5HE0A 5HE1A 2Q13A 1DYNA 4Z2NA 3MDBC 5J3YA 1PFJA 4KVGB 2KUPA 4WJ7A 3G9WA 1X1FA 2R09A 5C6RA 2J0JA 5GOWB 1V5MA 1KI1B 1EGXA 2I5CA 1U5EA 1KZGA 2XQNM 1M7RA 1ZM0A 1RJ2A 5JLJB 2LOXA 2AEHA 4HHVA 1FHOA 4HAZB 1EVHA 1UNPA 2DFKA 3P6AA 1FAOA 1GG3A 1QQGA 2ELBA 2MKRA 3ZDTA 1ISNA 2P0FA 4C0AA 2J0MA 1W1GA 2YRYA 1UNRA 1Z87A 4YONA 3BJIA 5DHAB 3TCAA 1X1GA 3TVVA 3D8DA 1XR0B 3QWMA 2DA0A 2OTXA 1BTKA 3SO6A 2RSGA 2DHKA 4HB3B 1H4RA 2DHJA 4ZRKA 1ZC3B 1OQNA 4HATB 1WG7A 1MAIA 1Y19B 2BCJA 1P6SA 3TW1A 1U29A 1DROA 1M7EA 1J0WA 1SHCA 4A6FB 2Z0OA 1NU2A 4YL8A 5KCVA 2X18A 4GZUA 4K81A 5J3QA 1U5DA 1EF1A 3NSUA 5CLQB 3DXEA 5JHGA 2YVCA 3KSYA 3FEHA 3AU4A 2CY5A 1DDMA 1B55A 3HW2B 2MFQA 2CAYA 3ODXA 1WVHA 2COCA 3M1IB 2HTHB 3PG7A 1ZVRA 5FI1A 2IYBA 3PZDA 4L6EA 2P8VA 2COAA 2RVBB 4F7UP 1DDVA 4MK0A 2Y7BA 2CODA 3GYOA 1XODA 2UZRA 5CLLB 2EMTA 3A8PA 2EC1A 4B6HA 4DX8A 2L1CA 1FGYA 2CY4A 2Y8GA 3KRXA 3WYFB 2KCJA 3D8FA 2DKQA 5DIFB 1XD4A 4ZRJA 1J19A 1MK9B 2Z0PA 3KY9A 1UPRA 1XKEA 1TJ6A 1H10A 1Q67A 3CXBB 5EFXA 1MPHA 2DHIA 2N23A 4KHOA 1RRPB 3F0WA 4WVFB 2YT1A 2LULA 4PQ0A 3CIKA 2FJLA 2VKIA 3HQCA 3ZVRA 1OY2A 4EKUA 1QC6A 2D9XA 5HE3A 1U2BA 1FOEA 1P5TA 1BTNA 2M38A 5L81A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VSZ A;  1WJ1 A;  3SNH A;  2H7D A;  1NI2 A;  1BAK A;  1DDW A;  1N3H A;  1MIZ B;  2RGN B;  2RLO A;  4HAV B;  2AL6 A;  3UZT A;  4NSW A;  4TKN A;  5DHF B;  1V88 A;  2QKL A;  3ODO A;  5C16 A;  3PP2 A;  4HAX B;  1TQZ A;  1WGQ A;  2NMB A;  3VOQ A;  2D4Q A;  1MIX A;  3FM8 C;  1KZ7 A;  5JP4 A;  1SGH A;  3SYX A;  4XWX A;  2DN6 A;  4F7G A;  2DX5 A;  4GN1 A;  3ML4 A;  2UVM A;  2KGX B;  2D9Y A;  5DH9 B;  2OQB A;  5KQ1 A;  4MY6 A;  5KQ4 A;  4HB4 B;  3PVW A;  4PNK A;  4GMV A;  4HB2 B;  2I1J A;  3X23 A;  4A5K A;  2RNR B;  3T06 A;  2GS0 A;  2DKP A;  2EJ8 A;  1V89 A;  1MKE A;  1WJM A;  2HE7 A;  1DBH A;  4NY0 A;  2G35 A;  4HAW B;  5LON B;  4A6F A;  1ZC4 B;  2DX1 A;  3BIN A;  2COF A;  1UEF A;  4H8S A;  2YSZ A;  3KZ1 A;  4K2P A;  3OAN A;  1IRS A;  3PVU A;  1U5G A;  4A6H A;  2CRF A;  4CHJ A;  4CYE A;  4DX9 0;  2W2X C;  1GC6 A;  4K17 A;  3TO1 A;  4DXA B;  2D11 A;  2YS5 A;  5C5B B;  4IOY X;  4F7H A;  2W2W A;  2MWN B;  2M14 A;  2ELA A;  3DXD A;  3RCP A;  4Y94 A;  1FB8 A;  3N7C A;  1ZSQ A;  3PSC A;  5D3V A;  2J0K A;  3LJU X;  2L2I A;  2N0Y A;  5LOP B;  4TYZ A;  4EJN A;  1EAZ A;  3WA0 A;  4KHA A;  2W2X D;  1W1D A;  4MT7 A;  1I7A A;  1UNQ A;  2D9Z A;  1FHW A;  1V5P A;  1PMS A;  2VRW B;  1WI1 A;  2PZ1 A;  1UPQ A;  1NTV A;  3P7Z A;  3MPX A;  4KHB B;  3VIA A;  2LG1 A;  1OMW A;  2DYQ A;  2P0H A;  2RUK B;  5JHH A;  3KRW A;  1AQC A;  1WGU A;  3FSS A;  1PLS A;  2I5F A;  2GJY A;  4D0N B;  3PVL A;  2D10 A;  2IFS A;  1U27 A;  3HK0 A;  4K2O A;  2K2U A;  3SUZ A;  1P3R A;  4EMO A;  1V5U A;  3O96 A;  3F5R A;  1X86 A;  2QKM A;  3AJ4 A;  3SV1 A;  2E2X A;  2YS3 A;  3PEG A;  2LYD A;  3U8Z A;  4WSF A;  1I2H A;  4IAP A;  2D9V A;  3ODW A;  4BBK A;  3A98 B;  2LKO A;  4HAU B;  1X05 A;  3A8Q A;  4HDQ A;  1LB1 A;  2R0D A;  4GMX B;  5D3W A;  4GPT B;  4ZRI A;  4Z2M B;  3ULC A;  2I1K A;  4IFS A;  2GCJ A;  4HAY B;  2GCL A;  2ROZ B;  2Z0Q A;  2DLW A;  1K5G B;  3QBV B;  2DYN A;  2P0D A;  2ADZ A;  5D27 A;  1Y5O A;  4GXB A;  1MK7 B;  4HB0 B;  2H7E A;  5HE2 A;  3D8E A;  4P7I A;  4HDO A;  1AWE A;  4KAX B;  5J3T A;  2ROV A;  2Y8F A;  3V5W A;  2MDX A;  1GC7 A;  3ULB A;  4CHM A;  1W1H A;  2UZS A;  1U5F A;  2V76 A;  2YT0 A;  2YF0 A;  2EMS A;  1FHX A;  2DTC A;  1X11 A;  5DI9 B;  1V61 A;  3TFM A;  1NTY A;  5FI0 A;  1E5W A;  4A6K A;  2D2Q A;  2J59 M;  2LOZ A;  1FGZ A;  2NZ8 B;  3U7D A;  1XX0 A;  2YS1 A;  3QIJ A;  1BWN A;  1XCG A;  2D9W A;  3AU5 A;  2ZPY A;  3GYP A;  5C5B A;  1TXD A;  5D3X A;  2K00 A;  3DXC A;  1K5D B;  4DBB A;  2JP2 A;  3IVF A;  5C79 A;  5D3Y A;  1LW3 A;  2K2J A;  5HE0 A;  5HE1 A;  2Q13 A;  1DYN A;  4Z2N A;  3MDB C;  5J3Y A;  1PFJ A;  4KVG B;  2KUP A;  4WJ7 A;  3G9W A;  1X1F A;  2R09 A;  5C6R A;  2J0J A;  5GOW B;  1V5M A;  1KI1 B;  1EGX A;  2I5C A;  1U5E A;  1KZG A;  2XQN M;  1M7R A;  1ZM0 A;  1RJ2 A;  5JLJ B;  2LOX A;  2AEH A;  4HHV A;  1FHO A;  4HAZ B;  1EVH A;  1UNP A;  2DFK A;  3P6A A;  1FAO A;  1GG3 A;  1QQG A;  2ELB A;  2MKR A;  3ZDT A;  1ISN A;  2P0F A;  4C0A A;  2J0M A;  1W1G A;  2YRY A;  1UNR A;  1Z87 A;  4YON A;  3BJI A;  5DHA B;  3TCA A;  1X1G A;  3TVV A;  3D8D A;  1XR0 B;  3QWM A;  2DA0 A;  2OTX A;  1BTK A;  3SO6 A;  2RSG A;  2DHK A;  4HB3 B;  1H4R A;  2DHJ A;  4ZRK A;  1ZC3 B;  1OQN A;  4HAT B;  1WG7 A;  1MAI A;  1Y19 B;  2BCJ A;  1P6S A;  3TW1 A;  1U29 A;  1DRO A;  1M7E A;  1J0W A;  1SHC A;  4A6F B;  2Z0O A;  1NU2 A;  4YL8 A;  5KCV A;  2X18 A;  4GZU A;  4K81 A;  5J3Q A;  1U5D A;  1EF1 A;  3NSU A;  5CLQ B;  3DXE A;  5JHG A;  2YVC A;  3KSY A;  3FEH A;  3AU4 A;  2CY5 A;  1DDM A;  1B55 A;  3HW2 B;  2MFQ A;  2CAY A;  3ODX A;  1WVH A;  2COC A;  3M1I B;  2HTH B;  3PG7 A;  1ZVR A;  5FI1 A;  2IYB A;  3PZD A;  4L6E A;  2P8V A;  2COA A;  2RVB B;  4F7U P;  1DDV A;  4MK0 A;  2Y7B A;  2COD A;  3GYO A;  1XOD A;  2UZR A;  5CLL B;  2EMT A;  3A8P A;  2EC1 A;  4B6H A;  4DX8 A;  2L1C A;  1FGY A;  2CY4 A;  2Y8G A;  3KRX A;  3WYF B;  2KCJ A;  3D8F A;  2DKQ A;  5DIF B;  1XD4 A;  4ZRJ A;  1J19 A;  1MK9 B;  2Z0P A;  3KY9 A;  1UPR A;  1XKE A;  1TJ6 A;  1H10 A;  1Q67 A;  3CXB B;  5EFX A;  1MPH A;  2DHI A;  2N23 A;  4KHO A;  1RRP B;  3F0W A;  4WVF B;  2YT1 A;  2LUL A;  4PQ0 A;  3CIK A;  2FJL A;  2VKI A;  3HQC A;  3ZVR A;  1OY2 A;  4EKU A;  1QC6 A;  2D9X A;  5HE3 A;  1U2B A;  1FOE A;  1P5T A;  1BTN A;  2M38 A;  5L81 A; 
#chains in the Genus database with same CATH topology
 2VSZ A;  3NW8 A;  3NWA A;  1WJ1 A;  2Z4D A;  3SNH A;  2H7D A;  2KIE A;  1NI2 A;  1BAK A;  2GUM A;  1DDW A;  1N3H A;  1MIZ B;  2RGN B;  2RLO A;  4HAV B;  2AL6 A;  3UZT A;  4NSW A;  4TKN A;  5DHF B;  4D6W A;  1V88 A;  2NBV A;  2QKL A;  3ODO A;  3HIE A;  5C16 A;  3PP2 A;  4HAX B;  1TQZ A;  1WGQ A;  2NMB A;  3VOQ A;  2D4Q A;  1MIX A;  3FM8 C;  1KZ7 A;  5JP4 A;  1SGH A;  3SYX A;  4XWX A;  2DN6 A;  4F7G A;  2DX5 A;  4GN1 A;  3ML4 A;  2UVM A;  2KGX B;  2D9Y A;  5DH9 B;  2OQB A;  5KQ1 A;  4MY6 A;  5KQ4 A;  4HB4 B;  3PVW A;  4PNK A;  4GMV A;  4HB2 B;  2I1J A;  3X23 A;  4A5K A;  2RNR B;  3T06 A;  2GS0 A;  2DKP A;  2EJ8 A;  4QJ3 B;  1T77 A;  1V89 A;  4HSI A;  1MKE A;  3NWD A;  1WJM A;  2HE7 A;  1DBH A;  4QJ5 B;  4NY0 A;  4OT1 A;  2G35 A;  4HAW B;  5LON B;  4A6F A;  1ZC4 B;  2K49 A;  2DX1 A;  3BIN A;  2COF A;  1UEF A;  4H8S A;  2YSZ A;  3KZ1 A;  4K2P A;  3OAN A;  1IRS A;  3PVU A;  1U5G A;  2Z14 A;  4A6H A;  2CRF A;  4CHJ A;  4CYE A;  4DX9 0;  2W2X C;  1GC6 A;  4GOU A;  4K17 A;  3TO1 A;  4DXA B;  2D11 A;  2YS5 A;  5C5B B;  4IOY X;  4F7H A;  2W2W A;  1MI1 A;  2MWN B;  4QXA B;  2M14 A;  2ELA A;  3DXD A;  3RCP A;  4Y94 A;  1FB8 A;  3N7C A;  1ZSQ A;  3PSC A;  5D3V A;  2J0K A;  3LJU X;  2KIG A;  2L2I A;  2N0Y A;  5LOP B;  4TYZ A;  4EJN A;  1EAZ A;  3WA0 A;  4KHA A;  2W2X D;  1W1D A;  3OHM B;  4MT7 A;  1I7A A;  1UNQ A;  2D9Z A;  1FHW A;  1V5P A;  1PMS A;  2VRW B;  4DIX A;  1WI1 A;  5I2S A;  2PZ1 A;  1UPQ A;  1NTV A;  3P7Z A;  3MPX A;  5LG4 B;  4KHB B;  3VIA A;  2LG1 A;  1OMW A;  2KR0 A;  2DYQ A;  2P0H A;  2RUK B;  5JHH A;  3KRW A;  1AQC A;  1WGU A;  3FSS A;  1PLS A;  2I5F A;  3A58 A;  2GJY A;  4D0N B;  3PVL A;  2D10 A;  2IFS A;  1U27 A;  3HK0 A;  4K2O A;  2K2U A;  3SUZ A;  1P3R A;  4EMO A;  1V5U A;  4L1R A;  3O96 A;  3F5R A;  1X86 A;  2RRF A;  2QKM A;  3AJ4 A;  3SV1 A;  2E2X A;  4GNK B;  2YS3 A;  3PEG A;  2LYD A;  3U8Z A;  4WSF A;  1I2H A;  4IAP A;  2D9V A;  3ODW A;  2FJU B;  4BBK A;  3A98 B;  2LKO A;  4HAU B;  1X05 A;  3A8Q A;  4HDQ A;  1LB1 A;  2R0D A;  4GMX B;  5D3W A;  4GPT B;  4ZRI A;  4Z2M B;  3ULC A;  2I1K A;  4IFS A;  2GCJ A;  4HAY B;  2GCL A;  2ROZ B;  2Z0Q A;  2DLW A;  1K5G B;  3QBV B;  2DYN A;  2P0D A;  2ADZ A;  5D27 A;  1Y5O A;  4GXB A;  5I2M A;  1MK7 B;  4HB0 B;  2H7E A;  5HE2 A;  3D8E A;  4P7I A;  4OSN A;  4HDO A;  1AWE A;  4KAX B;  5J3T A;  2ROV A;  2Y8F A;  3V5W A;  4QJ4 B;  2MDX A;  1GC7 A;  3ULB A;  3U12 A;  4CHM A;  1W1H A;  2UZS A;  1U5F A;  2V76 A;  2YT0 A;  2YF0 A;  2EMS A;  1FHX A;  2DTC A;  1X11 A;  5DI9 B;  1V61 A;  3TFM A;  1NTY A;  4CSQ A;  5FI0 A;  1E5W A;  4A6K A;  2D2Q A;  2J59 M;  2LOZ A;  1FGZ A;  2NZ8 B;  3U7D A;  1XX0 A;  2YS1 A;  3QIJ A;  1BWN A;  1XCG A;  2D9W A;  3AU5 A;  2ZPY A;  3GYP A;  5C5B A;  1TXD A;  5D3X A;  3B77 A;  2K00 A;  3DXC A;  3FVC A;  1K5D B;  4DBB A;  2JP2 A;  3IVF A;  5C79 A;  5D3Y A;  1LW3 A;  2K2J A;  5HE0 A;  5HE1 A;  2Q13 A;  1DYN A;  4Z2N A;  3MDB C;  5J3Y A;  1PFJ A;  4KVG B;  2KUP A;  4WJ7 A;  3G9W A;  1X1F A;  2R09 A;  5C6R A;  2J0J A;  5GOW B;  1V5M A;  1KI1 B;  1EGX A;  2I5C A;  1U5E A;  4KHB A;  1KZG A;  2XQN M;  1M7R A;  1ZM0 A;  1RJ2 A;  5JLJ B;  2LOX A;  2AEH A;  4HHV A;  1FHO A;  4HAZ B;  1EVH A;  1UNP A;  2DFK A;  3P6A A;  1FAO A;  1GG3 A;  1QQG A;  2ELB A;  2MKR A;  3NWF A;  3ZDT A;  1ISN A;  2P0F A;  4C0A A;  2J0M A;  3HSA A;  1W1G A;  2YRY A;  1UNR A;  2YT2 A;  1Z87 A;  4YON A;  3BJI A;  2KUQ A;  5DHA B;  5IRS A;  3TCA A;  1X1G A;  3TVV A;  3D8D A;  1XR0 B;  3QWM A;  1ZYI A;  2DA0 A;  2OTX A;  1BTK A;  3SO6 A;  2RSG A;  2DHK A;  2K8E A;  3DCX A;  4HB3 B;  1H4R A;  2DHJ A;  4ZRK A;  1ZC3 B;  1OQN A;  4HAT B;  1WG7 A;  1MAI A;  1Y19 B;  2BCJ A;  2ZKM X;  1P6S A;  3TW1 A;  1U29 A;  2Z59 A;  1DRO A;  1M7E A;  2Z13 A;  1J0W A;  1SHC A;  4A6F B;  2Z0O A;  1NU2 A;  4YL8 A;  5KCV A;  2X18 A;  4GZU A;  4K81 A;  5J3Q A;  1U5D A;  1EF1 A;  3NSU A;  5CLQ B;  3DXE A;  5JHG A;  2YVC A;  3KSY A;  3FEH A;  3AU4 A;  2CY5 A;  1DDM A;  1B55 A;  3HW2 B;  2MFQ A;  2CAY A;  3ODX A;  1WVH A;  2COC A;  3M1I B;  2HTH B;  3PG7 A;  1ZVR A;  5FI1 A;  2IYB A;  5M4Y B;  3PZD A;  4L6E A;  2P8V A;  2COA A;  2RVB B;  4F7U P;  1DDV A;  4MK0 A;  2Y7B A;  2COD A;  3GYO A;  1XOD A;  2UZR A;  5CLL B;  2EMT A;  3A8P A;  2EC1 A;  4B6H A;  4DX8 A;  2L1C A;  1FGY A;  2CY4 A;  2Y8G A;  3KRX A;  3WYF B;  2KCJ A;  3D8F A;  2DKQ A;  5DIF B;  1XD4 A;  4ZRJ A;  1J19 A;  1MK9 B;  2Z0P A;  3KY9 A;  1UPR A;  1XKE A;  1TJ6 A;  1H10 A;  1Q67 A;  3CXB B;  5EFX A;  1MPH A;  2DHI A;  2N23 A;  4KHO A;  2R2Y A;  1RRP B;  3F0W A;  4WVF B;  2YT1 A;  2LUL A;  4PQ0 A;  3CIK A;  2FJL A;  2VKI A;  3HQC A;  3ZVR A;  1OY2 A;  4EKU A;  1QC6 A;  2D9X A;  5HE3 A;  1U2B A;  1FOE A;  1P5T A;  1BTN A;  2M38 A;  5L81 A; 
#chains in the Genus database with same CATH homology
 2VSZ A;  1WJ1 A;  3SNH A;  2H7D A;  1NI2 A;  1BAK A;  1DDW A;  1N3H A;  1MIZ B;  2RGN B;  2RLO A;  4HAV B;  2AL6 A;  3UZT A;  4NSW A;  4TKN A;  5DHF B;  1V88 A;  2QKL A;  3ODO A;  5C16 A;  3PP2 A;  4HAX B;  1TQZ A;  1WGQ A;  2NMB A;  3VOQ A;  2D4Q A;  1MIX A;  3FM8 C;  1KZ7 A;  5JP4 A;  1SGH A;  3SYX A;  4XWX A;  2DN6 A;  4F7G A;  2DX5 A;  4GN1 A;  3ML4 A;  2UVM A;  2KGX B;  2D9Y A;  5DH9 B;  2OQB A;  5KQ1 A;  4MY6 A;  5KQ4 A;  4HB4 B;  3PVW A;  4PNK A;  4GMV A;  4HB2 B;  2I1J A;  3X23 A;  4A5K A;  2RNR B;  3T06 A;  2GS0 A;  2DKP A;  2EJ8 A;  1V89 A;  1MKE A;  1WJM A;  2HE7 A;  1DBH A;  4NY0 A;  2G35 A;  4HAW B;  5LON B;  4A6F A;  1ZC4 B;  2DX1 A;  3BIN A;  2COF A;  1UEF A;  4H8S A;  2YSZ A;  3KZ1 A;  4K2P A;  3OAN A;  1IRS A;  3PVU A;  1U5G A;  4A6H A;  2CRF A;  4CHJ A;  4CYE A;  4DX9 0;  2W2X C;  1GC6 A;  4K17 A;  3TO1 A;  4DXA B;  2D11 A;  2YS5 A;  5C5B B;  4IOY X;  4F7H A;  2W2W A;  2MWN B;  2M14 A;  2ELA A;  3DXD A;  3RCP A;  4Y94 A;  1FB8 A;  3N7C A;  1ZSQ A;  3PSC A;  5D3V A;  2J0K A;  3LJU X;  2L2I A;  2N0Y A;  5LOP B;  4TYZ A;  4EJN A;  1EAZ A;  3WA0 A;  4KHA A;  2W2X D;  1W1D A;  4MT7 A;  1I7A A;  1UNQ A;  2D9Z A;  1FHW A;  1V5P A;  1PMS A;  2VRW B;  1WI1 A;  2PZ1 A;  1UPQ A;  1NTV A;  3P7Z A;  3MPX A;  4KHB B;  3VIA A;  2LG1 A;  1OMW A;  2DYQ A;  2P0H A;  2RUK B;  5JHH A;  3KRW A;  1AQC A;  1WGU A;  3FSS A;  1PLS A;  2I5F A;  2GJY A;  4D0N B;  3PVL A;  2D10 A;  2IFS A;  1U27 A;  3HK0 A;  4K2O A;  2K2U A;  3SUZ A;  1P3R A;  4EMO A;  1V5U A;  3O96 A;  3F5R A;  1X86 A;  2QKM A;  3AJ4 A;  3SV1 A;  2E2X A;  2YS3 A;  3PEG A;  2LYD A;  3U8Z A;  4WSF A;  1I2H A;  4IAP A;  2D9V A;  3ODW A;  4BBK A;  3A98 B;  2LKO A;  4HAU B;  1X05 A;  3A8Q A;  4HDQ A;  1LB1 A;  2R0D A;  4GMX B;  5D3W A;  4GPT B;  4ZRI A;  4Z2M B;  3ULC A;  2I1K A;  4IFS A;  2GCJ A;  4HAY B;  2GCL A;  2ROZ B;  2Z0Q A;  2DLW A;  1K5G B;  3QBV B;  2DYN A;  2P0D A;  2ADZ A;  5D27 A;  1Y5O A;  4GXB A;  1MK7 B;  4HB0 B;  2H7E A;  5HE2 A;  3D8E A;  4P7I A;  4HDO A;  1AWE A;  4KAX B;  5J3T A;  2ROV A;  2Y8F A;  3V5W A;  2MDX A;  1GC7 A;  3ULB A;  4CHM A;  1W1H A;  2UZS A;  1U5F A;  2V76 A;  2YT0 A;  2YF0 A;  2EMS A;  1FHX A;  2DTC A;  1X11 A;  5DI9 B;  1V61 A;  3TFM A;  1NTY A;  5FI0 A;  1E5W A;  4A6K A;  2D2Q A;  2J59 M;  2LOZ A;  1FGZ A;  2NZ8 B;  3U7D A;  1XX0 A;  2YS1 A;  3QIJ A;  1BWN A;  1XCG A;  2D9W A;  3AU5 A;  2ZPY A;  3GYP A;  5C5B A;  1TXD A;  5D3X A;  2K00 A;  3DXC A;  1K5D B;  4DBB A;  2JP2 A;  3IVF A;  5C79 A;  5D3Y A;  1LW3 A;  2K2J A;  5HE0 A;  5HE1 A;  2Q13 A;  1DYN A;  4Z2N A;  3MDB C;  5J3Y A;  1PFJ A;  4KVG B;  2KUP A;  4WJ7 A;  3G9W A;  1X1F A;  2R09 A;  5C6R A;  2J0J A;  5GOW B;  1V5M A;  1KI1 B;  1EGX A;  2I5C A;  1U5E A;  1KZG A;  2XQN M;  1M7R A;  1ZM0 A;  1RJ2 A;  5JLJ B;  2LOX A;  2AEH A;  4HHV A;  1FHO A;  4HAZ B;  1EVH A;  1UNP A;  2DFK A;  3P6A A;  1FAO A;  1GG3 A;  1QQG A;  2ELB A;  2MKR A;  3ZDT A;  1ISN A;  2P0F A;  4C0A A;  2J0M A;  1W1G A;  2YRY A;  1UNR A;  1Z87 A;  4YON A;  3BJI A;  5DHA B;  3TCA A;  1X1G A;  3TVV A;  3D8D A;  1XR0 B;  3QWM A;  2DA0 A;  2OTX A;  1BTK A;  3SO6 A;  2RSG A;  2DHK A;  4HB3 B;  1H4R A;  2DHJ A;  4ZRK A;  1ZC3 B;  1OQN A;  4HAT B;  1WG7 A;  1MAI A;  1Y19 B;  2BCJ A;  1P6S A;  3TW1 A;  1U29 A;  1DRO A;  1M7E A;  1J0W A;  1SHC A;  4A6F B;  2Z0O A;  1NU2 A;  4YL8 A;  5KCV A;  2X18 A;  4GZU A;  4K81 A;  5J3Q A;  1U5D A;  1EF1 A;  3NSU A;  5CLQ B;  3DXE A;  5JHG A;  2YVC A;  3KSY A;  3FEH A;  3AU4 A;  2CY5 A;  1DDM A;  1B55 A;  3HW2 B;  2MFQ A;  2CAY A;  3ODX A;  1WVH A;  2COC A;  3M1I B;  2HTH B;  3PG7 A;  1ZVR A;  5FI1 A;  2IYB A;  3PZD A;  4L6E A;  2P8V A;  2COA A;  2RVB B;  4F7U P;  1DDV A;  4MK0 A;  2Y7B A;  2COD A;  3GYO A;  1XOD A;  2UZR A;  5CLL B;  2EMT A;  3A8P A;  2EC1 A;  4B6H A;  4DX8 A;  2L1C A;  1FGY A;  2CY4 A;  2Y8G A;  3KRX A;  3WYF B;  2KCJ A;  3D8F A;  2DKQ A;  5DIF B;  1XD4 A;  4ZRJ A;  1J19 A;  1MK9 B;  2Z0P A;  3KY9 A;  1UPR A;  1XKE A;  1TJ6 A;  1H10 A;  1Q67 A;  3CXB B;  5EFX A;  1MPH A;  2DHI A;  2N23 A;  4KHO A;  1RRP B;  3F0W A;  4WVF B;  2YT1 A;  2LUL A;  4PQ0 A;  3CIK A;  2FJL A;  2VKI A;  3HQC A;  3ZVR A;  1OY2 A;  4EKU A;  1QC6 A;  2D9X A;  5HE3 A;  1U2B A;  1FOE A;  1P5T A;  1BTN A;  2M38 A;  5L81 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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