3D8EA

Crystal structure of the human fe65-ptb1 domain (trigonal crystal form)
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
140
structure length
123
Chain Sequence
KCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYKDLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGDSGRERDFAYVARDKLTQMLKCHVFRCEAPAKNIATSLHEICSKIMAELE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Protein binding
source organism Homo sapiens
publication title Crystal structure of the human Fe65-PTB1 domain.
pubmed doi rcsb
molecule keywords Amyloid beta A4 precursor protein-binding family B member 1
total genus 28
structure length 123
sequence length 140
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2008-05-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 3d8eA00
4IFSA 5DHAB 2D2QA 1U2BA 2RVBB 1ZC3B 1I2HA 1MPHA 3DXDA 4PNKA 2V76A 2FJLA 4K2PA 1QC6A 1GG3A 1Z87A 4MT7A 2HE7A 2M14A 2CAYA 1DROA 4NSWA 2Y8FA 3KSYA 2MKRA 2RSGA 4P7IA 5LONB 1ISNA 1GC7A 1DDMA 3AU4A 1KI1B 2GCJA 4HAXB 3MPXA 2COAA 3N7CA 5CLLB 3TFMA 3QBVB 4Y94A 1WI1A 2GJYA 1OQNA 2QKLA 4CYEA 2D9VA 4C0AA 2YT0A 2Y7BA 2XQNM 3LJUX 2NZ8B 1OMWA 3V5WA 1V88A 2KCJA 3WYFB 1QQGA 2DFKA 2DHKA 1MK9B 3P6AA 2ELBA 2DA0A 1N3HA 3A98B 3PVWA 1J19A 1UPQA 2L2IA 1U29A 2YS5A 1SGHA 2AL6A 1V5MA 3HQCA 1XCGA 5D3WA 1V5UA 4HAWB 3PSCA 2W2XD 4WVFB 3BINA 3NSUA 2N0YA 2DHJA 1WGUA 4HATB 3T06A 5FI1A 2OTXA 5HE3A 3KY9A 1ZM0A 1FHWA 1MKEA 3PVLA 1W1GA 3OANA 1U5EA 2MWNB 2CY5A 1FAOA 4PQ0A 1ZVRA 2YS1A 4K17A 3TCAA 1V61A 5JHHA 1H4RA 1NU2A 5C5BA 4DBBA 4EMOA 1K5GB 3O96A 1U5DA 3AJ4A 3SNHA 1PMSA 3QIJA 4L6EA 3KRWA 3MDBC 3U7DA 2PZ1A 1I7AA 5D27A 2J59M 3TO1A 4HDQA 3CIKA 4MY6A 4NY0A 3CXBB 4Z2MB 1ZC4B 1WGQA 2YT1A 3DXCA 1Q67A 3UZTA 2K00A 4K81A 1BWNA 2DTCA 4DXAB 2IFSA 4HAYB 4MK0A 3ULBA 2ADZA 5DH9B 2KUPA 3F0WA 2VRWB 2CODA 2DKQA 3TVVA 4D0NB 1EVHA 2UZSA 4HAUB 1NI2A 2M38A 3TW1A 4A6KA 2J0MA 2D9WA 3SUZA 1MAIA 1EAZA 2RNRB 1XKEA 5KQ1A 1DDWA 4H8SA 4HB4B 3A8QA 2RLOA 3D8DA 1DBHA 4A6HA 2W2WA 2N23A 2W2XC 5LOPB 3SO6A 4WJ7A 3AU5A 1WG7A 3GYOA 4HB0B 3D8FA 1U5FA 2LKOA 2K2UA 5JP4A 2LYDA 5D3YA 3PP2A 4KAXB 1EGXA 1X11A 5C79A 4B6HA 2H7DA 1NTYA 1XR0B 2G35A 3GYPA 5J3QA 3PEGA 1BTNA 1J0WA 4F7GA 4TYZA 2E2XA 2D9ZA 3G9WA 2D10A 2I1KA 3ODOA 1OY2A 1WVHA 3SV1A 1MIXA 1XX0A 1PFJA 1EF1A 4YONA 4KHAA 2D9XA 1FHOA 1M7RA 2NMBA 5DIFB 2D4QA 5EFXA 3ODXA 1TQZA 4ZRJA 5HE2A 4DX90 1TJ6A 5KCVA 5FI0A 5HE0A 4TKNA 2K2JA 2L1CA 2X18A 2J0JA 1PLSA 2Y8GA 3WA0A 2R09A 1LW3A 1K5DB 2J0KA 2DHIA 3IVFA 4WSFA 1SHCA 1V5PA 4GPTB 2YRYA 4EKUA 2GS0A 2JP2A 1X1FA 3BJIA 2R0DA 4A6FB 3SYXA 2CRFA 1W1HA 1BTKA 2DX1A 1H10A 1P6SA 2OQBA 2UVMA 2LULA 1TXDA 2H7EA 3D8EA 2DKPA 2DYNA 2ZPYA 1MK7B 5D3VA 3ZDTA 2MFQA 3VIAA 1UPRA 3HW2B 1KZ7A 2DYQA 1KZGA 3ZVRA 3HK0A 4IAPA 2P8VA 2EMTA 3RCPA 3PG7A 3KRXA 4IOYX 1W1DA 2LOZA 1FHXA 2COFA 4DX8A 1P3RA 1XD4A 3QWMA 4KHBB 1M7EA 2D9YA 2Z0QA 1RRPB 5D3XA 3ULCA 4EJNA 5JLJB 1WJ1A 3PVUA 2EC1A 2BCJA 4KHOA 2AEHA 2YF0A 4ZRKA 4F7HA 2RGNB 1RJ2A 3U8ZA 4GMVA 2COCA 1P5TA 3P7ZA 2LG1A 5C16A 2LOXA 4YL8A 4CHJA 2YSZA 2KGXB 1X86A 1NTVA 3PZDA 2ELAA 2ROVA 1X1GA 1Y5OA 2UZRA 2QKMA 4HB3B 2HTHB 2I5FA 2D11A 5DI9B 4GMXB 2RUKB 3FEHA 1U27A 5L81A 3KZ1A 4XWXA 4K2OA 3VOQA 4HAZB 1Y19B 4ZRIA 5J3TA 2EMSA 1DYNA 1UNPA 1X05A 1UEFA 1FOEA 4HB2B 4HHVA 4KVGB 2CY4A 2MDXA 1IRSA 4HDOA 5HE1A 1UNRA 3DXEA 2I1JA 1U5GA 3ML4A 2DN6A 3FM8C 1AQCA 5DHFB 2Z0OA 1AWEA 5J3YA 2P0DA 5C6RA 1B55A 2EJ8A 2I5CA 2ROZB 1DDVA 4GZUA 3X23A 1XODA 5GOWB 1WJMA 1FB8A 4A5KA 1LB1A 5JHGA 1ZSQA 4F7UP 1GC6A 2Q13A 4CHMA 3A8PA 4GXBA 4A6FA 2P0FA 5CLQB 4GN1A 5KQ4A 2P0HA 1UNQA 2IYBA 2YVCA 4BBKA 1FGYA 2DLWA 3M1IB 3F5RA 1FGZA 5C5BB 4Z2NA 1BAKA 2DX5A 3FSSA 1V89A 1E5WA 2GCLA 2Z0PA 4HAVB 3ODWA 1MIZB 2VSZA 2YS3A 2VKIA
chains in the Genus database with same CATH superfamily
4IFSA 5DHAB 2D2QA 1U2BA 2RVBB 1ZC3B 1I2HA 4QJ5B 1MPHA 3DXDA 4KHBA 4PNKA 2V76A 2FJLA 4K2PA 1QC6A 1GG3A 1Z87A 4MT7A 4OSNA 2HE7A 2M14A 2CAYA 1DROA 4NSWA 2Y8FA 4CSQA 3KSYA 2MKRA 2Z13A 2RSGA 4P7IA 5LONB 1ISNA 1GC7A 1DDMA 3AU4A 1KI1B 2GCJA 4HAXB 3MPXA 2COAA 2YT2A 3N7CA 5CLLB 3TFMA 3QBVB 3NW8A 4Y94A 1WI1A 2GJYA 1OQNA 2QKLA 4CYEA 2D9VA 4C0AA 2YT0A 2Y7BA 2XQNM 3LJUX 2NZ8B 1OMWA 3V5WA 1V88A 2KCJA 3WYFB 1QQGA 2DFKA 2DHKA 1MK9B 3P6AA 2ELBA 2DA0A 1N3HA 3A98B 3PVWA 2K8EA 1J19A 1UPQA 2L2IA 1U29A 2KIGA 2YS5A 1SGHA 2AL6A 1V5MA 3HQCA 1XCGA 5D3WA 1V5UA 4HAWB 3PSCA 2W2XD 4WVFB 5I2SA 2RRFA 3BINA 4QXAB 3NSUA 2R2YA 2N0YA 2DHJA 1WGUA 4HATB 3U12A 3T06A 5FI1A 2OTXA 5HE3A 3KY9A 1ZM0A 1FHWA 1MKEA 3PVLA 1W1GA 3OANA 1U5EA 2MWNB 2CY5A 1FAOA 4PQ0A 1ZVRA 3HSAA 2YS1A 4GNKB 4K17A 3TCAA 1V61A 5JHHA 1H4RA 1NU2A 5C5BA 4DBBA 4EMOA 1K5GB 4L1RA 3O96A 1U5DA 3AJ4A 3SNHA 1PMSA 3QIJA 4L6EA 3KRWA 3MDBC 3U7DA 2PZ1A 1I7AA 5D27A 2J59M 3TO1A 4HDQA 3CIKA 4MY6A 4NY0A 3CXBB 4Z2MB 3HIEA 1ZC4B 1WGQA 2YT1A 3DXCA 1Q67A 4GOUA 3UZTA 2K00A 4K81A 1BWNA 5I2MA 2DTCA 4DXAB 2IFSA 4HAYB 4MK0A 3ULBA 2ADZA 5DH9B 2KUPA 3F0WA 2VRWB 2CODA 2DKQA 3TVVA 4D0NB 1EVHA 2UZSA 4HAUB 1NI2A 2M38A 3TW1A 4A6KA 4QJ3B 2J0MA 2D9WA 3SUZA 4QJ4B 1MAIA 1EAZA 2RNRB 1XKEA 5KQ1A 1DDWA 4H8SA 4HB4B 3A8QA 2RLOA 3D8DA 1DBHA 4HSIA 4A6HA 2W2WA 2N23A 2W2XC 5LOPB 3SO6A 4WJ7A 3AU5A 1WG7A 3GYOA 4HB0B 3D8FA 1U5FA 2LKOA 2K2UA 5JP4A 2LYDA 5D3YA 3PP2A 4KAXB 1EGXA 1X11A 5C79A 4B6HA 2H7DA 1NTYA 3NWDA 1XR0B 2G35A 3GYPA 5J3QA 3PEGA 1BTNA 1J0WA 4F7GA 4TYZA 2E2XA 3A58A 2D9ZA 3G9WA 2D10A 2I1KA 2K49A 3ODOA 1OY2A 1WVHA 3SV1A 1MIXA 1XX0A 1PFJA 1EF1A 4YONA 4KHAA 2D9XA 1FHOA 1M7RA 2NMBA 5DIFB 2D4QA 5EFXA 3ODXA 1TQZA 4ZRJA 2KIEA 5HE2A 4DX90 2GUMA 1TJ6A 5KCVA 5FI0A 5HE0A 4TKNA 2K2JA 2L1CA 2X18A 2J0JA 1PLSA 2Y8GA 3WA0A 2R09A 1LW3A 1K5DB 2FJUB 2J0KA 2Z4DA 2DHIA 3IVFA 4WSFA 1SHCA 1V5PA 4GPTB 2YRYA 4EKUA 2GS0A 2JP2A 1X1FA 3BJIA 2R0DA 4A6FB 3SYXA 2CRFA 1W1HA 1BTKA 2DX1A 1H10A 1P6SA 2OQBA 2UVMA 2LULA 3D8EA 1TXDA 2H7EA 2DKPA 2DYNA 2ZPYA 1MK7B 2Z59A 4D6WA 5D3VA 3ZDTA 2MFQA 3VIAA 1UPRA 3HW2B 1KZ7A 2DYQA 1KZGA 3ZVRA 3HK0A 4IAPA 2P8VA 2EMTA 3RCPA 3PG7A 3KRXA 4DIXA 4IOYX 1W1DA 2LOZA 1FHXA 2COFA 4DX8A 3B77A 1P3RA 1XD4A 3QWMA 4KHBB 1M7EA 2D9YA 2Z0QA 1RRPB 5D3XA 3ULCA 4EJNA 5JLJB 1WJ1A 3DCXA 3PVUA 2EC1A 2BCJA 4KHOA 2AEHA 2YF0A 4ZRKA 4F7HA 2RGNB 1RJ2A 3U8ZA 4GMVA 3OHMB 2COCA 1P5TA 3P7ZA 4OT1A 2LG1A 5C16A 2LOXA 4YL8A 4CHJA 2YSZA 2KGXB 1X86A 1NTVA 3PZDA 1T77A 3NWAA 2ELAA 2ROVA 1X1GA 1Y5OA 2UZRA 2QKMA 4HB3B 2HTHB 2I5FA 2D11A 5DI9B 4GMXB 2RUKB 3FEHA 1U27A 5L81A 1ZYIA 3KZ1A 4XWXA 4K2OA 3VOQA 4HAZB 1Y19B 4ZRIA 5J3TA 2EMSA 1DYNA 1UNPA 1X05A 1UEFA 5IRSA 1FOEA 2Z14A 4HB2B 4HHVA 4KVGB 2CY4A 2MDXA 1IRSA 4HDOA 5HE1A 1UNRA 3DXEA 2I1JA 1U5GA 3ML4A 5M4YB 2DN6A 3FM8C 1AQCA 5DHFB 2Z0OA 1AWEA 1MI1A 5J3YA 2P0DA 5C6RA 1B55A 2EJ8A 2KR0A 2I5CA 2ROZB 1DDVA 4GZUA 3X23A 1XODA 5GOWB 2ZKMX 2NBVA 1WJMA 1FB8A 4A5KA 1LB1A 5JHGA 1ZSQA 4F7UP 1GC6A 2Q13A 4CHMA 3A8PA 4GXBA 4A6FA 2P0FA 5CLQB 4GN1A 3NWFA 5KQ4A 2P0HA 1UNQA 2IYBA 2YVCA 4BBKA 1FGYA 2DLWA 3M1IB 3F5RA 1FGZA 5C5BB 4Z2NA 1BAKA 2DX5A 3FSSA 1V89A 2KUQA 1E5WA 2GCLA 5LG4B 2Z0PA 4HAVB 3FVCA 3ODWA 1MIZB 2VSZA 2YS3A 2VKIA
chains in the Genus database with same CATH topology
4IFSA 5DHAB 2D2QA 1U2BA 2RVBB 1ZC3B 1I2HA 1MPHA 3DXDA 4PNKA 2V76A 2FJLA 4K2PA 1QC6A 1GG3A 1Z87A 4MT7A 2HE7A 2M14A 2CAYA 1DROA 4NSWA 2Y8FA 3KSYA 2MKRA 2RSGA 4P7IA 5LONB 1ISNA 1GC7A 1DDMA 3AU4A 1KI1B 2GCJA 4HAXB 3MPXA 2COAA 3N7CA 5CLLB 3TFMA 3QBVB 4Y94A 1WI1A 2GJYA 1OQNA 2QKLA 4CYEA 2D9VA 4C0AA 2YT0A 2Y7BA 2XQNM 3LJUX 2NZ8B 1OMWA 3V5WA 1V88A 2KCJA 3WYFB 1QQGA 2DFKA 2DHKA 1MK9B 3P6AA 2ELBA 2DA0A 1N3HA 3A98B 3PVWA 1J19A 1UPQA 2L2IA 1U29A 2YS5A 1SGHA 2AL6A 1V5MA 3HQCA 1XCGA 5D3WA 1V5UA 4HAWB 3PSCA 2W2XD 4WVFB 3BINA 3NSUA 2N0YA 2DHJA 1WGUA 4HATB 3T06A 5FI1A 2OTXA 5HE3A 3KY9A 1ZM0A 1FHWA 1MKEA 3PVLA 1W1GA 3OANA 1U5EA 2MWNB 2CY5A 1FAOA 4PQ0A 1ZVRA 2YS1A 4K17A 3TCAA 1V61A 5JHHA 1H4RA 1NU2A 5C5BA 4DBBA 4EMOA 1K5GB 3O96A 1U5DA 3AJ4A 3SNHA 1PMSA 3QIJA 4L6EA 3KRWA 3MDBC 3U7DA 2PZ1A 1I7AA 5D27A 2J59M 3TO1A 4HDQA 3CIKA 4MY6A 4NY0A 3CXBB 4Z2MB 1ZC4B 1WGQA 2YT1A 3DXCA 1Q67A 3UZTA 2K00A 4K81A 1BWNA 2DTCA 4DXAB 2IFSA 4HAYB 4MK0A 3ULBA 2ADZA 5DH9B 2KUPA 3F0WA 2VRWB 2CODA 2DKQA 3TVVA 4D0NB 1EVHA 2UZSA 4HAUB 1NI2A 2M38A 3TW1A 4A6KA 2J0MA 2D9WA 3SUZA 1MAIA 1EAZA 2RNRB 1XKEA 5KQ1A 1DDWA 4H8SA 4HB4B 3A8QA 2RLOA 3D8DA 1DBHA 4A6HA 2W2WA 2N23A 2W2XC 5LOPB 3SO6A 4WJ7A 3AU5A 1WG7A 3GYOA 4HB0B 3D8FA 1U5FA 2LKOA 2K2UA 5JP4A 2LYDA 5D3YA 3PP2A 4KAXB 1EGXA 1X11A 5C79A 4B6HA 2H7DA 1NTYA 1XR0B 2G35A 3GYPA 5J3QA 3PEGA 1BTNA 1J0WA 4F7GA 4TYZA 2E2XA 2D9ZA 3G9WA 2D10A 2I1KA 3ODOA 1OY2A 1WVHA 3SV1A 1MIXA 1XX0A 1PFJA 1EF1A 4YONA 4KHAA 2D9XA 1FHOA 1M7RA 2NMBA 5DIFB 2D4QA 5EFXA 3ODXA 1TQZA 4ZRJA 5HE2A 4DX90 1TJ6A 5KCVA 5FI0A 5HE0A 4TKNA 2K2JA 2L1CA 2X18A 2J0JA 1PLSA 2Y8GA 3WA0A 2R09A 1LW3A 1K5DB 2J0KA 2DHIA 3IVFA 4WSFA 1SHCA 1V5PA 4GPTB 2YRYA 4EKUA 2GS0A 2JP2A 1X1FA 3BJIA 2R0DA 4A6FB 3SYXA 2CRFA 1W1HA 1BTKA 2DX1A 1H10A 1P6SA 2OQBA 2UVMA 2LULA 1TXDA 2H7EA 3D8EA 2DKPA 2DYNA 2ZPYA 1MK7B 5D3VA 3ZDTA 2MFQA 3VIAA 1UPRA 3HW2B 1KZ7A 2DYQA 1KZGA 3ZVRA 3HK0A 4IAPA 2P8VA 2EMTA 3RCPA 3PG7A 3KRXA 4IOYX 1W1DA 2LOZA 1FHXA 2COFA 4DX8A 1P3RA 1XD4A 3QWMA 4KHBB 1M7EA 2D9YA 2Z0QA 1RRPB 5D3XA 3ULCA 4EJNA 5JLJB 1WJ1A 3PVUA 2EC1A 2BCJA 4KHOA 2AEHA 2YF0A 4ZRKA 4F7HA 2RGNB 1RJ2A 3U8ZA 4GMVA 2COCA 1P5TA 3P7ZA 2LG1A 5C16A 2LOXA 4YL8A 4CHJA 2YSZA 2KGXB 1X86A 1NTVA 3PZDA 2ELAA 2ROVA 1X1GA 1Y5OA 2UZRA 2QKMA 4HB3B 2HTHB 2I5FA 2D11A 5DI9B 4GMXB 2RUKB 3FEHA 1U27A 5L81A 3KZ1A 4XWXA 4K2OA 3VOQA 4HAZB 1Y19B 4ZRIA 5J3TA 2EMSA 1DYNA 1UNPA 1X05A 1UEFA 1FOEA 4HB2B 4HHVA 4KVGB 2CY4A 2MDXA 1IRSA 4HDOA 5HE1A 1UNRA 3DXEA 2I1JA 1U5GA 3ML4A 2DN6A 3FM8C 1AQCA 5DHFB 2Z0OA 1AWEA 5J3YA 2P0DA 5C6RA 1B55A 2EJ8A 2I5CA 2ROZB 1DDVA 4GZUA 3X23A 1XODA 5GOWB 1WJMA 1FB8A 4A5KA 1LB1A 5JHGA 1ZSQA 4F7UP 1GC6A 2Q13A 4CHMA 3A8PA 4GXBA 4A6FA 2P0FA 5CLQB 4GN1A 5KQ4A 2P0HA 1UNQA 2IYBA 2YVCA 4BBKA 1FGYA 2DLWA 3M1IB 3F5RA 1FGZA 5C5BB 4Z2NA 1BAKA 2DX5A 3FSSA 1V89A 1E5WA 2GCLA 2Z0PA 4HAVB 3ODWA 1MIZB 2VSZA 2YS3A 2VKIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IFS A;  5DHA B;  2D2Q A;  1U2B A;  2RVB B;  1ZC3 B;  1I2H A;  1MPH A;  3DXD A;  4PNK A;  2V76 A;  2FJL A;  4K2P A;  1QC6 A;  1GG3 A;  1Z87 A;  4MT7 A;  2HE7 A;  2M14 A;  2CAY A;  1DRO A;  4NSW A;  2Y8F A;  3KSY A;  2MKR A;  2RSG A;  4P7I A;  5LON B;  1ISN A;  1GC7 A;  1DDM A;  3AU4 A;  1KI1 B;  2GCJ A;  4HAX B;  3MPX A;  2COA A;  3N7C A;  5CLL B;  3TFM A;  3QBV B;  4Y94 A;  1WI1 A;  2GJY A;  1OQN A;  2QKL A;  4CYE A;  2D9V A;  4C0A A;  2YT0 A;  2Y7B A;  2XQN M;  3LJU X;  2NZ8 B;  1OMW A;  3V5W A;  1V88 A;  2KCJ A;  3WYF B;  1QQG A;  2DFK A;  2DHK A;  1MK9 B;  3P6A A;  2ELB A;  2DA0 A;  1N3H A;  3A98 B;  3PVW A;  1J19 A;  1UPQ A;  2L2I A;  1U29 A;  2YS5 A;  1SGH A;  2AL6 A;  1V5M A;  3HQC A;  1XCG A;  5D3W A;  1V5U A;  4HAW B;  3PSC A;  2W2X D;  4WVF B;  3BIN A;  3NSU A;  2N0Y A;  2DHJ A;  1WGU A;  4HAT B;  3T06 A;  5FI1 A;  2OTX A;  5HE3 A;  3KY9 A;  1ZM0 A;  1FHW A;  1MKE A;  3PVL A;  1W1G A;  3OAN A;  1U5E A;  2MWN B;  2CY5 A;  1FAO A;  4PQ0 A;  1ZVR A;  2YS1 A;  4K17 A;  3TCA A;  1V61 A;  5JHH A;  1H4R A;  1NU2 A;  5C5B A;  4DBB A;  4EMO A;  1K5G B;  3O96 A;  1U5D A;  3AJ4 A;  3SNH A;  1PMS A;  3QIJ A;  4L6E A;  3KRW A;  3MDB C;  3U7D A;  2PZ1 A;  1I7A A;  5D27 A;  2J59 M;  3TO1 A;  4HDQ A;  3CIK A;  4MY6 A;  4NY0 A;  3CXB B;  4Z2M B;  1ZC4 B;  1WGQ A;  2YT1 A;  3DXC A;  1Q67 A;  3UZT A;  2K00 A;  4K81 A;  1BWN A;  2DTC A;  4DXA B;  2IFS A;  4HAY B;  4MK0 A;  3ULB A;  2ADZ A;  5DH9 B;  2KUP A;  3F0W A;  2VRW B;  2COD A;  2DKQ A;  3TVV A;  4D0N B;  1EVH A;  2UZS A;  4HAU B;  1NI2 A;  2M38 A;  3TW1 A;  4A6K A;  2J0M A;  2D9W A;  3SUZ A;  1MAI A;  1EAZ A;  2RNR B;  1XKE A;  5KQ1 A;  1DDW A;  4H8S A;  4HB4 B;  3A8Q A;  2RLO A;  3D8D A;  1DBH A;  4A6H A;  2W2W A;  2N23 A;  2W2X C;  5LOP B;  3SO6 A;  4WJ7 A;  3AU5 A;  1WG7 A;  3GYO A;  4HB0 B;  3D8F A;  1U5F A;  2LKO A;  2K2U A;  5JP4 A;  2LYD A;  5D3Y A;  3PP2 A;  4KAX B;  1EGX A;  1X11 A;  5C79 A;  4B6H A;  2H7D A;  1NTY A;  1XR0 B;  2G35 A;  3GYP A;  5J3Q A;  3PEG A;  1BTN A;  1J0W A;  4F7G A;  4TYZ A;  2E2X A;  2D9Z A;  3G9W A;  2D10 A;  2I1K A;  3ODO A;  1OY2 A;  1WVH A;  3SV1 A;  1MIX A;  1XX0 A;  1PFJ A;  1EF1 A;  4YON A;  4KHA A;  2D9X A;  1FHO A;  1M7R A;  2NMB A;  5DIF B;  2D4Q A;  5EFX A;  3ODX A;  1TQZ A;  4ZRJ A;  5HE2 A;  4DX9 0;  1TJ6 A;  5KCV A;  5FI0 A;  5HE0 A;  4TKN A;  2K2J A;  2L1C A;  2X18 A;  2J0J A;  1PLS A;  2Y8G A;  3WA0 A;  2R09 A;  1LW3 A;  1K5D B;  2J0K A;  2DHI A;  3IVF A;  4WSF A;  1SHC A;  1V5P A;  4GPT B;  2YRY A;  4EKU A;  2GS0 A;  2JP2 A;  1X1F A;  3BJI A;  2R0D A;  4A6F B;  3SYX A;  2CRF A;  1W1H A;  1BTK A;  2DX1 A;  1H10 A;  1P6S A;  2OQB A;  2UVM A;  2LUL A;  1TXD A;  2H7E A;  3D8E A;  2DKP A;  2DYN A;  2ZPY A;  1MK7 B;  5D3V A;  3ZDT A;  2MFQ A;  3VIA A;  1UPR A;  3HW2 B;  1KZ7 A;  2DYQ A;  1KZG A;  3ZVR A;  3HK0 A;  4IAP A;  2P8V A;  2EMT A;  3RCP A;  3PG7 A;  3KRX A;  4IOY X;  1W1D A;  2LOZ A;  1FHX A;  2COF A;  4DX8 A;  1P3R A;  1XD4 A;  3QWM A;  4KHB B;  1M7E A;  2D9Y A;  2Z0Q A;  1RRP B;  5D3X A;  3ULC A;  4EJN A;  5JLJ B;  1WJ1 A;  3PVU A;  2EC1 A;  2BCJ A;  4KHO A;  2AEH A;  2YF0 A;  4ZRK A;  4F7H A;  2RGN B;  1RJ2 A;  3U8Z A;  4GMV A;  2COC A;  1P5T A;  3P7Z A;  2LG1 A;  5C16 A;  2LOX A;  4YL8 A;  4CHJ A;  2YSZ A;  2KGX B;  1X86 A;  1NTV A;  3PZD A;  2ELA A;  2ROV A;  1X1G A;  1Y5O A;  2UZR A;  2QKM A;  4HB3 B;  2HTH B;  2I5F A;  2D11 A;  5DI9 B;  4GMX B;  2RUK B;  3FEH A;  1U27 A;  5L81 A;  3KZ1 A;  4XWX A;  4K2O A;  3VOQ A;  4HAZ B;  1Y19 B;  4ZRI A;  5J3T A;  2EMS A;  1DYN A;  1UNP A;  1X05 A;  1UEF A;  1FOE A;  4HB2 B;  4HHV A;  4KVG B;  2CY4 A;  2MDX A;  1IRS A;  4HDO A;  5HE1 A;  1UNR A;  3DXE A;  2I1J A;  1U5G A;  3ML4 A;  2DN6 A;  3FM8 C;  1AQC A;  5DHF B;  2Z0O A;  1AWE A;  5J3Y A;  2P0D A;  5C6R A;  1B55 A;  2EJ8 A;  2I5C A;  2ROZ B;  1DDV A;  4GZU A;  3X23 A;  1XOD A;  5GOW B;  1WJM A;  1FB8 A;  4A5K A;  1LB1 A;  5JHG A;  1ZSQ A;  4F7U P;  1GC6 A;  2Q13 A;  4CHM A;  3A8P A;  4GXB A;  4A6F A;  2P0F A;  5CLQ B;  4GN1 A;  5KQ4 A;  2P0H A;  1UNQ A;  2IYB A;  2YVC A;  4BBK A;  1FGY A;  2DLW A;  3M1I B;  3F5R A;  1FGZ A;  5C5B B;  4Z2N A;  1BAK A;  2DX5 A;  3FSS A;  1V89 A;  1E5W A;  2GCL A;  2Z0P A;  4HAV B;  3ODW A;  1MIZ B;  2VSZ A;  2YS3 A;  2VKI A; 
#chains in the Genus database with same CATH topology
 4IFS A;  5DHA B;  2D2Q A;  1U2B A;  2RVB B;  1ZC3 B;  1I2H A;  4QJ5 B;  1MPH A;  3DXD A;  4KHB A;  4PNK A;  2V76 A;  2FJL A;  4K2P A;  1QC6 A;  1GG3 A;  1Z87 A;  4MT7 A;  4OSN A;  2HE7 A;  2M14 A;  2CAY A;  1DRO A;  4NSW A;  2Y8F A;  4CSQ A;  3KSY A;  2MKR A;  2Z13 A;  2RSG A;  4P7I A;  5LON B;  1ISN A;  1GC7 A;  1DDM A;  3AU4 A;  1KI1 B;  2GCJ A;  4HAX B;  3MPX A;  2COA A;  2YT2 A;  3N7C A;  5CLL B;  3TFM A;  3QBV B;  3NW8 A;  4Y94 A;  1WI1 A;  2GJY A;  1OQN A;  2QKL A;  4CYE A;  2D9V A;  4C0A A;  2YT0 A;  2Y7B A;  2XQN M;  3LJU X;  2NZ8 B;  1OMW A;  3V5W A;  1V88 A;  2KCJ A;  3WYF B;  1QQG A;  2DFK A;  2DHK A;  1MK9 B;  3P6A A;  2ELB A;  2DA0 A;  1N3H A;  3A98 B;  3PVW A;  2K8E A;  1J19 A;  1UPQ A;  2L2I A;  1U29 A;  2KIG A;  2YS5 A;  1SGH A;  2AL6 A;  1V5M A;  3HQC A;  1XCG A;  5D3W A;  1V5U A;  4HAW B;  3PSC A;  2W2X D;  4WVF B;  5I2S A;  2RRF A;  3BIN A;  4QXA B;  3NSU A;  2R2Y A;  2N0Y A;  2DHJ A;  1WGU A;  4HAT B;  3U12 A;  3T06 A;  5FI1 A;  2OTX A;  5HE3 A;  3KY9 A;  1ZM0 A;  1FHW A;  1MKE A;  3PVL A;  1W1G A;  3OAN A;  1U5E A;  2MWN B;  2CY5 A;  1FAO A;  4PQ0 A;  1ZVR A;  3HSA A;  2YS1 A;  4GNK B;  4K17 A;  3TCA A;  1V61 A;  5JHH A;  1H4R A;  1NU2 A;  5C5B A;  4DBB A;  4EMO A;  1K5G B;  4L1R A;  3O96 A;  1U5D A;  3AJ4 A;  3SNH A;  1PMS A;  3QIJ A;  4L6E A;  3KRW A;  3MDB C;  3U7D A;  2PZ1 A;  1I7A A;  5D27 A;  2J59 M;  3TO1 A;  4HDQ A;  3CIK A;  4MY6 A;  4NY0 A;  3CXB B;  4Z2M B;  3HIE A;  1ZC4 B;  1WGQ A;  2YT1 A;  3DXC A;  1Q67 A;  4GOU A;  3UZT A;  2K00 A;  4K81 A;  1BWN A;  5I2M A;  2DTC A;  4DXA B;  2IFS A;  4HAY B;  4MK0 A;  3ULB A;  2ADZ A;  5DH9 B;  2KUP A;  3F0W A;  2VRW B;  2COD A;  2DKQ A;  3TVV A;  4D0N B;  1EVH A;  2UZS A;  4HAU B;  1NI2 A;  2M38 A;  3TW1 A;  4A6K A;  4QJ3 B;  2J0M A;  2D9W A;  3SUZ A;  4QJ4 B;  1MAI A;  1EAZ A;  2RNR B;  1XKE A;  5KQ1 A;  1DDW A;  4H8S A;  4HB4 B;  3A8Q A;  2RLO A;  3D8D A;  1DBH A;  4HSI A;  4A6H A;  2W2W A;  2N23 A;  2W2X C;  5LOP B;  3SO6 A;  4WJ7 A;  3AU5 A;  1WG7 A;  3GYO A;  4HB0 B;  3D8F A;  1U5F A;  2LKO A;  2K2U A;  5JP4 A;  2LYD A;  5D3Y A;  3PP2 A;  4KAX B;  1EGX A;  1X11 A;  5C79 A;  4B6H A;  2H7D A;  1NTY A;  3NWD A;  1XR0 B;  2G35 A;  3GYP A;  5J3Q A;  3PEG A;  1BTN A;  1J0W A;  4F7G A;  4TYZ A;  2E2X A;  3A58 A;  2D9Z A;  3G9W A;  2D10 A;  2I1K A;  2K49 A;  3ODO A;  1OY2 A;  1WVH A;  3SV1 A;  1MIX A;  1XX0 A;  1PFJ A;  1EF1 A;  4YON A;  4KHA A;  2D9X A;  1FHO A;  1M7R A;  2NMB A;  5DIF B;  2D4Q A;  5EFX A;  3ODX A;  1TQZ A;  4ZRJ A;  2KIE A;  5HE2 A;  4DX9 0;  2GUM A;  1TJ6 A;  5KCV A;  5FI0 A;  5HE0 A;  4TKN A;  2K2J A;  2L1C A;  2X18 A;  2J0J A;  1PLS A;  2Y8G A;  3WA0 A;  2R09 A;  1LW3 A;  1K5D B;  2FJU B;  2J0K A;  2Z4D A;  2DHI A;  3IVF A;  4WSF A;  1SHC A;  1V5P A;  4GPT B;  2YRY A;  4EKU A;  2GS0 A;  2JP2 A;  1X1F A;  3BJI A;  2R0D A;  4A6F B;  3SYX A;  2CRF A;  1W1H A;  1BTK A;  2DX1 A;  1H10 A;  1P6S A;  2OQB A;  2UVM A;  2LUL A;  3D8E A;  1TXD A;  2H7E A;  2DKP A;  2DYN A;  2ZPY A;  1MK7 B;  2Z59 A;  4D6W A;  5D3V A;  3ZDT A;  2MFQ A;  3VIA A;  1UPR A;  3HW2 B;  1KZ7 A;  2DYQ A;  1KZG A;  3ZVR A;  3HK0 A;  4IAP A;  2P8V A;  2EMT A;  3RCP A;  3PG7 A;  3KRX A;  4DIX A;  4IOY X;  1W1D A;  2LOZ A;  1FHX A;  2COF A;  4DX8 A;  3B77 A;  1P3R A;  1XD4 A;  3QWM A;  4KHB B;  1M7E A;  2D9Y A;  2Z0Q A;  1RRP B;  5D3X A;  3ULC A;  4EJN A;  5JLJ B;  1WJ1 A;  3DCX A;  3PVU A;  2EC1 A;  2BCJ A;  4KHO A;  2AEH A;  2YF0 A;  4ZRK A;  4F7H A;  2RGN B;  1RJ2 A;  3U8Z A;  4GMV A;  3OHM B;  2COC A;  1P5T A;  3P7Z A;  4OT1 A;  2LG1 A;  5C16 A;  2LOX A;  4YL8 A;  4CHJ A;  2YSZ A;  2KGX B;  1X86 A;  1NTV A;  3PZD A;  1T77 A;  3NWA A;  2ELA A;  2ROV A;  1X1G A;  1Y5O A;  2UZR A;  2QKM A;  4HB3 B;  2HTH B;  2I5F A;  2D11 A;  5DI9 B;  4GMX B;  2RUK B;  3FEH A;  1U27 A;  5L81 A;  1ZYI A;  3KZ1 A;  4XWX A;  4K2O A;  3VOQ A;  4HAZ B;  1Y19 B;  4ZRI A;  5J3T A;  2EMS A;  1DYN A;  1UNP A;  1X05 A;  1UEF A;  5IRS A;  1FOE A;  2Z14 A;  4HB2 B;  4HHV A;  4KVG B;  2CY4 A;  2MDX A;  1IRS A;  4HDO A;  5HE1 A;  1UNR A;  3DXE A;  2I1J A;  1U5G A;  3ML4 A;  5M4Y B;  2DN6 A;  3FM8 C;  1AQC A;  5DHF B;  2Z0O A;  1AWE A;  1MI1 A;  5J3Y A;  2P0D A;  5C6R A;  1B55 A;  2EJ8 A;  2KR0 A;  2I5C A;  2ROZ B;  1DDV A;  4GZU A;  3X23 A;  1XOD A;  5GOW B;  2ZKM X;  2NBV A;  1WJM A;  1FB8 A;  4A5K A;  1LB1 A;  5JHG A;  1ZSQ A;  4F7U P;  1GC6 A;  2Q13 A;  4CHM A;  3A8P A;  4GXB A;  4A6F A;  2P0F A;  5CLQ B;  4GN1 A;  3NWF A;  5KQ4 A;  2P0H A;  1UNQ A;  2IYB A;  2YVC A;  4BBK A;  1FGY A;  2DLW A;  3M1I B;  3F5R A;  1FGZ A;  5C5B B;  4Z2N A;  1BAK A;  2DX5 A;  3FSS A;  1V89 A;  2KUQ A;  1E5W A;  2GCL A;  5LG4 B;  2Z0P A;  4HAV B;  3FVC A;  3ODW A;  1MIZ B;  2VSZ A;  2YS3 A;  2VKI A; 
#chains in the Genus database with same CATH homology
 4IFS A;  5DHA B;  2D2Q A;  1U2B A;  2RVB B;  1ZC3 B;  1I2H A;  1MPH A;  3DXD A;  4PNK A;  2V76 A;  2FJL A;  4K2P A;  1QC6 A;  1GG3 A;  1Z87 A;  4MT7 A;  2HE7 A;  2M14 A;  2CAY A;  1DRO A;  4NSW A;  2Y8F A;  3KSY A;  2MKR A;  2RSG A;  4P7I A;  5LON B;  1ISN A;  1GC7 A;  1DDM A;  3AU4 A;  1KI1 B;  2GCJ A;  4HAX B;  3MPX A;  2COA A;  3N7C A;  5CLL B;  3TFM A;  3QBV B;  4Y94 A;  1WI1 A;  2GJY A;  1OQN A;  2QKL A;  4CYE A;  2D9V A;  4C0A A;  2YT0 A;  2Y7B A;  2XQN M;  3LJU X;  2NZ8 B;  1OMW A;  3V5W A;  1V88 A;  2KCJ A;  3WYF B;  1QQG A;  2DFK A;  2DHK A;  1MK9 B;  3P6A A;  2ELB A;  2DA0 A;  1N3H A;  3A98 B;  3PVW A;  1J19 A;  1UPQ A;  2L2I A;  1U29 A;  2YS5 A;  1SGH A;  2AL6 A;  1V5M A;  3HQC A;  1XCG A;  5D3W A;  1V5U A;  4HAW B;  3PSC A;  2W2X D;  4WVF B;  3BIN A;  3NSU A;  2N0Y A;  2DHJ A;  1WGU A;  4HAT B;  3T06 A;  5FI1 A;  2OTX A;  5HE3 A;  3KY9 A;  1ZM0 A;  1FHW A;  1MKE A;  3PVL A;  1W1G A;  3OAN A;  1U5E A;  2MWN B;  2CY5 A;  1FAO A;  4PQ0 A;  1ZVR A;  2YS1 A;  4K17 A;  3TCA A;  1V61 A;  5JHH A;  1H4R A;  1NU2 A;  5C5B A;  4DBB A;  4EMO A;  1K5G B;  3O96 A;  1U5D A;  3AJ4 A;  3SNH A;  1PMS A;  3QIJ A;  4L6E A;  3KRW A;  3MDB C;  3U7D A;  2PZ1 A;  1I7A A;  5D27 A;  2J59 M;  3TO1 A;  4HDQ A;  3CIK A;  4MY6 A;  4NY0 A;  3CXB B;  4Z2M B;  1ZC4 B;  1WGQ A;  2YT1 A;  3DXC A;  1Q67 A;  3UZT A;  2K00 A;  4K81 A;  1BWN A;  2DTC A;  4DXA B;  2IFS A;  4HAY B;  4MK0 A;  3ULB A;  2ADZ A;  5DH9 B;  2KUP A;  3F0W A;  2VRW B;  2COD A;  2DKQ A;  3TVV A;  4D0N B;  1EVH A;  2UZS A;  4HAU B;  1NI2 A;  2M38 A;  3TW1 A;  4A6K A;  2J0M A;  2D9W A;  3SUZ A;  1MAI A;  1EAZ A;  2RNR B;  1XKE A;  5KQ1 A;  1DDW A;  4H8S A;  4HB4 B;  3A8Q A;  2RLO A;  3D8D A;  1DBH A;  4A6H A;  2W2W A;  2N23 A;  2W2X C;  5LOP B;  3SO6 A;  4WJ7 A;  3AU5 A;  1WG7 A;  3GYO A;  4HB0 B;  3D8F A;  1U5F A;  2LKO A;  2K2U A;  5JP4 A;  2LYD A;  5D3Y A;  3PP2 A;  4KAX B;  1EGX A;  1X11 A;  5C79 A;  4B6H A;  2H7D A;  1NTY A;  1XR0 B;  2G35 A;  3GYP A;  5J3Q A;  3PEG A;  1BTN A;  1J0W A;  4F7G A;  4TYZ A;  2E2X A;  2D9Z A;  3G9W A;  2D10 A;  2I1K A;  3ODO A;  1OY2 A;  1WVH A;  3SV1 A;  1MIX A;  1XX0 A;  1PFJ A;  1EF1 A;  4YON A;  4KHA A;  2D9X A;  1FHO A;  1M7R A;  2NMB A;  5DIF B;  2D4Q A;  5EFX A;  3ODX A;  1TQZ A;  4ZRJ A;  5HE2 A;  4DX9 0;  1TJ6 A;  5KCV A;  5FI0 A;  5HE0 A;  4TKN A;  2K2J A;  2L1C A;  2X18 A;  2J0J A;  1PLS A;  2Y8G A;  3WA0 A;  2R09 A;  1LW3 A;  1K5D B;  2J0K A;  2DHI A;  3IVF A;  4WSF A;  1SHC A;  1V5P A;  4GPT B;  2YRY A;  4EKU A;  2GS0 A;  2JP2 A;  1X1F A;  3BJI A;  2R0D A;  4A6F B;  3SYX A;  2CRF A;  1W1H A;  1BTK A;  2DX1 A;  1H10 A;  1P6S A;  2OQB A;  2UVM A;  2LUL A;  1TXD A;  2H7E A;  3D8E A;  2DKP A;  2DYN A;  2ZPY A;  1MK7 B;  5D3V A;  3ZDT A;  2MFQ A;  3VIA A;  1UPR A;  3HW2 B;  1KZ7 A;  2DYQ A;  1KZG A;  3ZVR A;  3HK0 A;  4IAP A;  2P8V A;  2EMT A;  3RCP A;  3PG7 A;  3KRX A;  4IOY X;  1W1D A;  2LOZ A;  1FHX A;  2COF A;  4DX8 A;  1P3R A;  1XD4 A;  3QWM A;  4KHB B;  1M7E A;  2D9Y A;  2Z0Q A;  1RRP B;  5D3X A;  3ULC A;  4EJN A;  5JLJ B;  1WJ1 A;  3PVU A;  2EC1 A;  2BCJ A;  4KHO A;  2AEH A;  2YF0 A;  4ZRK A;  4F7H A;  2RGN B;  1RJ2 A;  3U8Z A;  4GMV A;  2COC A;  1P5T A;  3P7Z A;  2LG1 A;  5C16 A;  2LOX A;  4YL8 A;  4CHJ A;  2YSZ A;  2KGX B;  1X86 A;  1NTV A;  3PZD A;  2ELA A;  2ROV A;  1X1G A;  1Y5O A;  2UZR A;  2QKM A;  4HB3 B;  2HTH B;  2I5F A;  2D11 A;  5DI9 B;  4GMX B;  2RUK B;  3FEH A;  1U27 A;  5L81 A;  3KZ1 A;  4XWX A;  4K2O A;  3VOQ A;  4HAZ B;  1Y19 B;  4ZRI A;  5J3T A;  2EMS A;  1DYN A;  1UNP A;  1X05 A;  1UEF A;  1FOE A;  4HB2 B;  4HHV A;  4KVG B;  2CY4 A;  2MDX A;  1IRS A;  4HDO A;  5HE1 A;  1UNR A;  3DXE A;  2I1J A;  1U5G A;  3ML4 A;  2DN6 A;  3FM8 C;  1AQC A;  5DHF B;  2Z0O A;  1AWE A;  5J3Y A;  2P0D A;  5C6R A;  1B55 A;  2EJ8 A;  2I5C A;  2ROZ B;  1DDV A;  4GZU A;  3X23 A;  1XOD A;  5GOW B;  1WJM A;  1FB8 A;  4A5K A;  1LB1 A;  5JHG A;  1ZSQ A;  4F7U P;  1GC6 A;  2Q13 A;  4CHM A;  3A8P A;  4GXB A;  4A6F A;  2P0F A;  5CLQ B;  4GN1 A;  5KQ4 A;  2P0H A;  1UNQ A;  2IYB A;  2YVC A;  4BBK A;  1FGY A;  2DLW A;  3M1I B;  3F5R A;  1FGZ A;  5C5B B;  4Z2N A;  1BAK A;  2DX5 A;  3FSS A;  1V89 A;  1E5W A;  2GCL A;  2Z0P A;  4HAV B;  3ODW A;  1MIZ B;  2VSZ A;  2YS3 A;  2VKI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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