3DXDA

Crystal structure of the intracellular domain of human app (t668e mutant) in complex with fe65-ptb2
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
131
structure length
131
Chain Sequence
NELVQKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEAVLGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQKCLDARSQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Amyloid beta A4 protein-binding family B member 1
total genus 37
structure length 131
sequence length 131
chains with identical sequence C
ec nomenclature
pdb deposition date 2008-07-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00640 PID Phosphotyrosine interaction domain (PTB/PID)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 3dxdA00
5LONB 4Z2NA 4H8SA 1W1DA 1SHCA 2YVCA 3DXDA 3WYFB 2Y7BA 3U7DA 3U8ZA 2E2XA 4Y94A 3DXCA 3PVWA 3RCPA 1OY2A 3QIJA 4Z2MB 1X11A 5D3VA 3VIAA 3SNHA 3HQCA 1RRPB 2N23A 3KRWA 1EF1A 4HAZB 3SUZA 4DBBA 4HAYB 4F7UP 2GCLA 2ROZB 2VRWB 2D9WA 2VSZA 1AQCA 2DA0A 4K2OA 1V5UA 5D3XA 5DHAB 4DX8A 2YS3A 1X1GA 4CHJA 1U29A 4GMVA 2ZPYA 3PP2A 4A6FA 2DX1A 4EKUA 4C0AA 1MAIA 1K5DB 2RVBB 4PQ0A 3AU5A 3MPXA 3A98B 5HE0A 2YT0A 1KZ7A 5D3WA 1EGXA 1U5EA 2LOXA 2J0JA 2DHJA 1BTNA 5J3TA 2DHIA 1BAKA 2Y8FA 1GG3A 2BCJA 2DHKA 2IFSA 2DKQA 1W1HA 4BBKA 4HB4B 3D8FA 1ZM0A 1ZVRA 4NY0A 5KCVA 3AJ4A 2EMTA 1NTVA 1BWNA 2W2XC 3UZTA 1KZGA 1PFJA 1SGHA 2PZ1A 2DN6A 2Y8GA 1IRSA 2LOZA 1P3RA 1DDMA 2D9YA 1X1FA 2P8VA 4HB0B 5JLJB 1J19A 1FHXA 3QWMA 4K2PA 3KY9A 3PVLA 4MY6A 1H4RA 2D11A 2FJLA 1E5WA 1UNPA 1MIZB 2QKLA 4ZRKA 2N0YA 3BJIA 1KI1B 1OMWA 1DROA 1WG7A 3LJUX 3ODOA 4K81A 2RSGA 2RLOA 1QC6A 3G9WA 1QQGA 4GN1A 2OQBA 1WGUA 4WVFB 5JHHA 2OTXA 2JP2A 2J0KA 3P7ZA 4HHVA 5JP4A 1V89A 4F7HA 1M7EA 2CAYA 4HAUB 1U2BA 2YS1A 3SO6A 3F5RA 1WGQA 2DFKA 3O96A 2HTHB 3T06A 5LOPB 1MPHA 2YS5A 2COAA 5FI1A 4KHOA 2GJYA 4A6KA 2ROVA 5C5BB 5DHFB 3V5WA 1Z87A 4PNKA 3X23A 2NZ8B 2KUPA 4CHMA 2RGNB 2P0HA 4A6HA 1XKEA 2CY4A 1DDVA 3SV1A 2K2JA 1TJ6A 3AU4A 2EC1A 3D8DA 1DBHA 2YT1A 3PSCA 2R0DA 2P0FA 1H10A 1Y19B 3D8EA 1V61A 2COFA 5JHGA 2ELBA 1I2HA 2DLWA 2ADZA 2LKOA 3FEHA 3A8PA 2UZRA 2EMSA 3ZDTA 2DKPA 2K2UA 2Z0PA 1U5FA 4IFSA 1X05A 1MK9B 2D9XA 4MK0A 2R09A 1UNRA 4HAXB 1M7RA 2IYBA 1PLSA 2LYDA 1ZC4B 1WVHA 2QKMA 4HDQA 2D9ZA 1EVHA 1WI1A 2KCJA 3DXEA 2YSZA 1MIXA 2AL6A 4HB3B 3TVVA 1DDWA 2DYNA 1B55A 1Y5OA 4A5KA 3VOQA 3OANA 1WJMA 4TYZA 5DI9B 3ODWA 2D9VA 1XX0A 4HDOA 1GC6A 1UEFA 3KSYA 2M38A 4HB2B 3KZ1A 3SYXA 5DH9B 5CLQB 2EJ8A 3PVUA 2VKIA 1V5PA 4K17A 4ZRJA 1U27A 2UVMA 2DTCA 5HE3A 3CIKA 1NTYA 2MFQA 1P5TA 2Z0QA 3QBVB 4XWXA 4NSWA 2CY5A 4GMXB 2MDXA 1RJ2A 2L1CA 1W1GA 3A8QA 1OQNA 4GPTB 5D27A 4HAWB 1DYNA 3GYPA 5EFXA 1P6SA 2I1KA 3TW1A 5C6RA 1J0WA 1FGZA 1EAZA 4KAXB 3CXBB 4TKNA 5HE2A 2W2WA 3PEGA 2GCJA 3MDBC 5C16A 1GC7A 4GXBA 3FM8C 4YONA 3FSSA 2LG1A 5L81A 4IAPA 1I7AA 2YRYA 2YF0A 1PMSA 3F0WA 4A6FB 1N3HA 1UPQA 1Q67A 2H7EA 5DIFB 5C5BA 1U5GA 1FB8A 5KQ4A 2D4QA 1TQZA 5J3QA 1V88A 1K5GB 1V5MA 3TFMA 2HE7A 2DYQA 5CLLB 1MK7B 4P7IA 3PG7A 2XQNM 4WSFA 1TXDA 3ULBA 1XCGA 4CYEA 4KVGB 2CRFA 2DX5A 4B6HA 5C79A 3P6AA 2CODA 2COCA 4KHAA 1NI2A 1UPRA 3KRXA 1U5DA 2MKRA 4IOYX 3WA0A 4F7GA 4EJNA 5HE1A 2ELAA 2X18A 1XD4A 5D3YA 2G35A 3PZDA 5KQ1A 2L2IA 3M1IB 1XR0B 5J3YA 4HATB 2UZSA 3BINA 1BTKA 4GZUA 2H7DA 2I5FA 5GOWB 2W2XD 2RUKB 1FHWA 3HK0A 3ZVRA 4D0NB 1MKEA 3TO1A 4DX90 2LULA 2GS0A 4L6EA 2KGXB 2NMBA 2J0MA 2I5CA 1ISNA 1FHOA 4WJ7A 1XODA 3ODXA 2V76A 2I1JA 2MWNB 2P0DA 1ZSQA 2AEHA 2RNRB 3HW2B 1FAOA 2J59M 2Z0OA 4MT7A 2Q13A 1ZC3B 3TCAA 3NSUA 4EMOA 3ML4A 3GYOA 3ULCA 2M14A 1LW3A 1LB1A 3IVFA 4ZRIA 1WJ1A 2K00A 1FOEA 2D10A 1AWEA 1X86A 5FI0A 1UNQA 4YL8A 3N7CA 1NU2A 4KHBB 2D2QA 1FGYA 4DXAB 4HAVB
chains in the Genus database with same CATH superfamily
5LONB 4Z2NA 4QJ5B 4H8SA 1W1DA 1SHCA 2GUMA 2YVCA 3DXDA 3WYFB 2Y7BA 3U7DA 3U8ZA 2E2XA 3NW8A 4Y94A 3DXCA 3PVWA 3RCPA 1OY2A 2NBVA 3QIJA 4Z2MB 1X11A 5D3VA 3VIAA 3SNHA 3HQCA 1RRPB 2N23A 3KRWA 1EF1A 4HAZB 3SUZA 4DBBA 4HAYB 4F7UP 2GCLA 2ROZB 2VRWB 2D9WA 2VSZA 1AQCA 2DA0A 4K2OA 2K8EA 1V5UA 5D3XA 5DHAB 4DX8A 2YS3A 1X1GA 4CHJA 1U29A 4GMVA 2ZPYA 3PP2A 4A6FA 2DX1A 4EKUA 4C0AA 1MAIA 1K5DB 2RVBB 4PQ0A 3AU5A 2Z14A 3MPXA 3A98B 5HE0A 2YT0A 1KZ7A 5D3WA 1EGXA 1U5EA 2LOXA 2J0JA 2DHJA 1BTNA 5J3TA 2DHIA 1BAKA 2Y8FA 1GG3A 2BCJA 2DHKA 2IFSA 2DKQA 1W1HA 4BBKA 4HB4B 2KIEA 3D8FA 1ZM0A 1ZVRA 4NY0A 5KCVA 3AJ4A 2EMTA 1NTVA 1BWNA 2W2XC 3UZTA 1KZGA 1PFJA 1SGHA 2PZ1A 2DN6A 2Y8GA 1IRSA 2LOZA 1P3RA 1DDMA 2D9YA 1X1FA 2P8VA 4HB0B 5JLJB 1J19A 1T77A 2Z4DA 1FHXA 3QWMA 4K2PA 3KY9A 3PVLA 4MY6A 3NWFA 5I2SA 1H4RA 2D11A 2FJLA 1E5WA 4GNKB 1UNPA 1MIZB 2QKLA 4ZRKA 2N0YA 3BJIA 1KI1B 1OMWA 1DROA 1WG7A 3LJUX 3ODOA 4K81A 2RSGA 5IRSA 2RLOA 1QC6A 3G9WA 1QQGA 4GN1A 2OQBA 1WGUA 4OT1A 4WVFB 5JHHA 2OTXA 2JP2A 2J0KA 3P7ZA 4HHVA 5JP4A 1V89A 4F7HA 1M7EA 2CAYA 4HAUB 1U2BA 2YS1A 3SO6A 1MI1A 3F5RA 5M4YB 4QJ4B 1WGQA 2DFKA 3O96A 2HTHB 3T06A 5LOPB 1MPHA 2YS5A 2COAA 4KHBA 5FI1A 4KHOA 2GJYA 4A6KA 2ROVA 2FJUB 5C5BB 2RRFA 5DHFB 3V5WA 1Z87A 4PNKA 3X23A 3NWDA 2NZ8B 2KUPA 4CHMA 2RGNB 2P0HA 4A6HA 1XKEA 2CY4A 1DDVA 3SV1A 2K2JA 1TJ6A 3AU4A 2EC1A 3D8DA 1DBHA 3FVCA 2YT1A 3PSCA 2R0DA 3HIEA 2P0FA 1H10A 4L1RA 1Y19B 3D8EA 1V61A 2COFA 5JHGA 2ELBA 1I2HA 2DLWA 4D6WA 2ADZA 2LKOA 2Z59A 3FEHA 3A8PA 2UZRA 2EMSA 3ZDTA 2DKPA 2K2UA 2Z0PA 1U5FA 4IFSA 1X05A 1MK9B 2D9XA 2K49A 2KUQA 4MK0A 2R09A 1UNRA 4HAXB 1M7RA 2IYBA 1PLSA 2LYDA 1ZC4B 1WVHA 2QKMA 4HDQA 2D9ZA 4OSNA 1EVHA 1WI1A 2KCJA 3DXEA 2YSZA 1MIXA 2AL6A 4HB3B 3TVVA 1DDWA 2DYNA 1B55A 1Y5OA 4A5KA 3VOQA 3OANA 4HSIA 1WJMA 4QJ3B 4TYZA 3NWAA 5DI9B 3ODWA 2D9VA 1XX0A 4HDOA 1GC6A 1UEFA 3KSYA 2M38A 4HB2B 3KZ1A 3SYXA 5DH9B 5CLQB 2EJ8A 3PVUA 2VKIA 1V5PA 4K17A 4ZRJA 1U27A 2UVMA 2DTCA 5HE3A 3CIKA 1NTYA 2MFQA 1P5TA 2Z0QA 3QBVB 4XWXA 4NSWA 2CY5A 4GMXB 2MDXA 1RJ2A 2L1CA 1W1GA 3A8QA 1OQNA 4GPTB 5D27A 4HAWB 4DIXA 1DYNA 3GYPA 5EFXA 1P6SA 2I1KA 3TW1A 5C6RA 1J0WA 1FGZA 1EAZA 4KAXB 3CXBB 4TKNA 5HE2A 2W2WA 3PEGA 2GCJA 3MDBC 5C16A 1GC7A 2Z13A 4GXBA 3FM8C 4YONA 3FSSA 2LG1A 5L81A 4IAPA 1I7AA 2YRYA 2YF0A 1PMSA 3F0WA 4A6FB 1N3HA 1UPQA 2R2YA 1Q67A 2H7EA 5DIFB 5C5BA 1U5GA 1FB8A 3OHMB 5LG4B 5KQ4A 2D4QA 1TQZA 5J3QA 1V88A 1K5GB 1V5MA 3B77A 3TFMA 2HE7A 2DYQA 5CLLB 1MK7B 4P7IA 3PG7A 2XQNM 4WSFA 1TXDA 3ULBA 1XCGA 4CYEA 4KVGB 2CRFA 2ZKMX 2DX5A 4B6HA 5C79A 3P6AA 4GOUA 2CODA 2COCA 4KHAA 1NI2A 1UPRA 3KRXA 1U5DA 2MKRA 4IOYX 3WA0A 4F7GA 4EJNA 5HE1A 2ELAA 1ZYIA 2X18A 1XD4A 5D3YA 2G35A 3PZDA 5KQ1A 2L2IA 3M1IB 1XR0B 5J3YA 2KR0A 4HATB 2UZSA 3BINA 1BTKA 4GZUA 2H7DA 2I5FA 5GOWB 2W2XD 2RUKB 3DCXA 1FHWA 3HK0A 5I2MA 3ZVRA 3A58A 4D0NB 1MKEA 3TO1A 4DX90 2LULA 2GS0A 4L6EA 2KGXB 2NMBA 2J0MA 2I5CA 1ISNA 1FHOA 4WJ7A 1XODA 3ODXA 2V76A 2I1JA 2MWNB 2P0DA 1ZSQA 2AEHA 2YT2A 2RNRB 3HW2B 1FAOA 2J59M 2Z0OA 4MT7A 2Q13A 1ZC3B 3TCAA 3NSUA 4CSQA 4EMOA 3ML4A 3GYOA 3ULCA 2M14A 1LW3A 1LB1A 3IVFA 2KIGA 4ZRIA 1WJ1A 2K00A 1FOEA 2D10A 1AWEA 1X86A 5FI0A 1UNQA 3U12A 4YL8A 3N7CA 1NU2A 4KHBB 3HSAA 2D2QA 1FGYA 4QXAB 4DXAB 4HAVB
chains in the Genus database with same CATH topology
5LONB 4Z2NA 4H8SA 1W1DA 1SHCA 2YVCA 3DXDA 3WYFB 2Y7BA 3U7DA 3U8ZA 2E2XA 4Y94A 3DXCA 3PVWA 3RCPA 1OY2A 3QIJA 4Z2MB 1X11A 5D3VA 3VIAA 3SNHA 3HQCA 1RRPB 2N23A 3KRWA 1EF1A 4HAZB 3SUZA 4DBBA 4HAYB 4F7UP 2GCLA 2ROZB 2VRWB 2D9WA 2VSZA 1AQCA 2DA0A 4K2OA 1V5UA 5D3XA 5DHAB 4DX8A 2YS3A 1X1GA 4CHJA 1U29A 4GMVA 2ZPYA 3PP2A 4A6FA 2DX1A 4EKUA 4C0AA 1MAIA 1K5DB 2RVBB 4PQ0A 3AU5A 3MPXA 3A98B 5HE0A 2YT0A 1KZ7A 5D3WA 1EGXA 1U5EA 2LOXA 2J0JA 2DHJA 1BTNA 5J3TA 2DHIA 1BAKA 2Y8FA 1GG3A 2BCJA 2DHKA 2IFSA 2DKQA 1W1HA 4BBKA 4HB4B 3D8FA 1ZM0A 1ZVRA 4NY0A 5KCVA 3AJ4A 2EMTA 1NTVA 1BWNA 2W2XC 3UZTA 1KZGA 1PFJA 1SGHA 2PZ1A 2DN6A 2Y8GA 1IRSA 2LOZA 1P3RA 1DDMA 2D9YA 1X1FA 2P8VA 4HB0B 5JLJB 1J19A 1FHXA 3QWMA 4K2PA 3KY9A 3PVLA 4MY6A 1H4RA 2D11A 2FJLA 1E5WA 1UNPA 1MIZB 2QKLA 4ZRKA 2N0YA 3BJIA 1KI1B 1OMWA 1DROA 1WG7A 3LJUX 3ODOA 4K81A 2RSGA 2RLOA 1QC6A 3G9WA 1QQGA 4GN1A 2OQBA 1WGUA 4WVFB 5JHHA 2OTXA 2JP2A 2J0KA 3P7ZA 4HHVA 5JP4A 1V89A 4F7HA 1M7EA 2CAYA 4HAUB 1U2BA 2YS1A 3SO6A 3F5RA 1WGQA 2DFKA 3O96A 2HTHB 3T06A 5LOPB 1MPHA 2YS5A 2COAA 5FI1A 4KHOA 2GJYA 4A6KA 2ROVA 5C5BB 5DHFB 3V5WA 1Z87A 4PNKA 3X23A 2NZ8B 2KUPA 4CHMA 2RGNB 2P0HA 4A6HA 1XKEA 2CY4A 1DDVA 3SV1A 2K2JA 1TJ6A 3AU4A 2EC1A 3D8DA 1DBHA 2YT1A 3PSCA 2R0DA 2P0FA 1H10A 1Y19B 3D8EA 1V61A 2COFA 5JHGA 2ELBA 1I2HA 2DLWA 2ADZA 2LKOA 3FEHA 3A8PA 2UZRA 2EMSA 3ZDTA 2DKPA 2K2UA 2Z0PA 1U5FA 4IFSA 1X05A 1MK9B 2D9XA 4MK0A 2R09A 1UNRA 4HAXB 1M7RA 2IYBA 1PLSA 2LYDA 1ZC4B 1WVHA 2QKMA 4HDQA 2D9ZA 1EVHA 1WI1A 2KCJA 3DXEA 2YSZA 1MIXA 2AL6A 4HB3B 3TVVA 1DDWA 2DYNA 1B55A 1Y5OA 4A5KA 3VOQA 3OANA 1WJMA 4TYZA 5DI9B 3ODWA 2D9VA 1XX0A 4HDOA 1GC6A 1UEFA 3KSYA 2M38A 4HB2B 3KZ1A 3SYXA 5DH9B 5CLQB 2EJ8A 3PVUA 2VKIA 1V5PA 4K17A 4ZRJA 1U27A 2UVMA 2DTCA 5HE3A 3CIKA 1NTYA 2MFQA 1P5TA 2Z0QA 3QBVB 4XWXA 4NSWA 2CY5A 4GMXB 2MDXA 1RJ2A 2L1CA 1W1GA 3A8QA 1OQNA 4GPTB 5D27A 4HAWB 1DYNA 3GYPA 5EFXA 1P6SA 2I1KA 3TW1A 5C6RA 1J0WA 1FGZA 1EAZA 4KAXB 3CXBB 4TKNA 5HE2A 2W2WA 3PEGA 2GCJA 3MDBC 5C16A 1GC7A 4GXBA 3FM8C 4YONA 3FSSA 2LG1A 5L81A 4IAPA 1I7AA 2YRYA 2YF0A 1PMSA 3F0WA 4A6FB 1N3HA 1UPQA 1Q67A 2H7EA 5DIFB 5C5BA 1U5GA 1FB8A 5KQ4A 2D4QA 1TQZA 5J3QA 1V88A 1K5GB 1V5MA 3TFMA 2HE7A 2DYQA 5CLLB 1MK7B 4P7IA 3PG7A 2XQNM 4WSFA 1TXDA 3ULBA 1XCGA 4CYEA 4KVGB 2CRFA 2DX5A 4B6HA 5C79A 3P6AA 2CODA 2COCA 4KHAA 1NI2A 1UPRA 3KRXA 1U5DA 2MKRA 4IOYX 3WA0A 4F7GA 4EJNA 5HE1A 2ELAA 2X18A 1XD4A 5D3YA 2G35A 3PZDA 5KQ1A 2L2IA 3M1IB 1XR0B 5J3YA 4HATB 2UZSA 3BINA 1BTKA 4GZUA 2H7DA 2I5FA 5GOWB 2W2XD 2RUKB 1FHWA 3HK0A 3ZVRA 4D0NB 1MKEA 3TO1A 4DX90 2LULA 2GS0A 4L6EA 2KGXB 2NMBA 2J0MA 2I5CA 1ISNA 1FHOA 4WJ7A 1XODA 3ODXA 2V76A 2I1JA 2MWNB 2P0DA 1ZSQA 2AEHA 2RNRB 3HW2B 1FAOA 2J59M 2Z0OA 4MT7A 2Q13A 1ZC3B 3TCAA 3NSUA 4EMOA 3ML4A 3GYOA 3ULCA 2M14A 1LW3A 1LB1A 3IVFA 4ZRIA 1WJ1A 2K00A 1FOEA 2D10A 1AWEA 1X86A 5FI0A 1UNQA 4YL8A 3N7CA 1NU2A 4KHBB 2D2QA 1FGYA 4DXAB 4HAVB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5LON B;  4Z2N A;  4H8S A;  1W1D A;  1SHC A;  2YVC A;  3DXD A;  3WYF B;  2Y7B A;  3U7D A;  3U8Z A;  2E2X A;  4Y94 A;  3DXC A;  3PVW A;  3RCP A;  1OY2 A;  3QIJ A;  4Z2M B;  1X11 A;  5D3V A;  3VIA A;  3SNH A;  3HQC A;  1RRP B;  2N23 A;  3KRW A;  1EF1 A;  4HAZ B;  3SUZ A;  4DBB A;  4HAY B;  4F7U P;  2GCL A;  2ROZ B;  2VRW B;  2D9W A;  2VSZ A;  1AQC A;  2DA0 A;  4K2O A;  1V5U A;  5D3X A;  5DHA B;  4DX8 A;  2YS3 A;  1X1G A;  4CHJ A;  1U29 A;  4GMV A;  2ZPY A;  3PP2 A;  4A6F A;  2DX1 A;  4EKU A;  4C0A A;  1MAI A;  1K5D B;  2RVB B;  4PQ0 A;  3AU5 A;  3MPX A;  3A98 B;  5HE0 A;  2YT0 A;  1KZ7 A;  5D3W A;  1EGX A;  1U5E A;  2LOX A;  2J0J A;  2DHJ A;  1BTN A;  5J3T A;  2DHI A;  1BAK A;  2Y8F A;  1GG3 A;  2BCJ A;  2DHK A;  2IFS A;  2DKQ A;  1W1H A;  4BBK A;  4HB4 B;  3D8F A;  1ZM0 A;  1ZVR A;  4NY0 A;  5KCV A;  3AJ4 A;  2EMT A;  1NTV A;  1BWN A;  2W2X C;  3UZT A;  1KZG A;  1PFJ A;  1SGH A;  2PZ1 A;  2DN6 A;  2Y8G A;  1IRS A;  2LOZ A;  1P3R A;  1DDM A;  2D9Y A;  1X1F A;  2P8V A;  4HB0 B;  5JLJ B;  1J19 A;  1FHX A;  3QWM A;  4K2P A;  3KY9 A;  3PVL A;  4MY6 A;  1H4R A;  2D11 A;  2FJL A;  1E5W A;  1UNP A;  1MIZ B;  2QKL A;  4ZRK A;  2N0Y A;  3BJI A;  1KI1 B;  1OMW A;  1DRO A;  1WG7 A;  3LJU X;  3ODO A;  4K81 A;  2RSG A;  2RLO A;  1QC6 A;  3G9W A;  1QQG A;  4GN1 A;  2OQB A;  1WGU A;  4WVF B;  5JHH A;  2OTX A;  2JP2 A;  2J0K A;  3P7Z A;  4HHV A;  5JP4 A;  1V89 A;  4F7H A;  1M7E A;  2CAY A;  4HAU B;  1U2B A;  2YS1 A;  3SO6 A;  3F5R A;  1WGQ A;  2DFK A;  3O96 A;  2HTH B;  3T06 A;  5LOP B;  1MPH A;  2YS5 A;  2COA A;  5FI1 A;  4KHO A;  2GJY A;  4A6K A;  2ROV A;  5C5B B;  5DHF B;  3V5W A;  1Z87 A;  4PNK A;  3X23 A;  2NZ8 B;  2KUP A;  4CHM A;  2RGN B;  2P0H A;  4A6H A;  1XKE A;  2CY4 A;  1DDV A;  3SV1 A;  2K2J A;  1TJ6 A;  3AU4 A;  2EC1 A;  3D8D A;  1DBH A;  2YT1 A;  3PSC A;  2R0D A;  2P0F A;  1H10 A;  1Y19 B;  3D8E A;  1V61 A;  2COF A;  5JHG A;  2ELB A;  1I2H A;  2DLW A;  2ADZ A;  2LKO A;  3FEH A;  3A8P A;  2UZR A;  2EMS A;  3ZDT A;  2DKP A;  2K2U A;  2Z0P A;  1U5F A;  4IFS A;  1X05 A;  1MK9 B;  2D9X A;  4MK0 A;  2R09 A;  1UNR A;  4HAX B;  1M7R A;  2IYB A;  1PLS A;  2LYD A;  1ZC4 B;  1WVH A;  2QKM A;  4HDQ A;  2D9Z A;  1EVH A;  1WI1 A;  2KCJ A;  3DXE A;  2YSZ A;  1MIX A;  2AL6 A;  4HB3 B;  3TVV A;  1DDW A;  2DYN A;  1B55 A;  1Y5O A;  4A5K A;  3VOQ A;  3OAN A;  1WJM A;  4TYZ A;  5DI9 B;  3ODW A;  2D9V A;  1XX0 A;  4HDO A;  1GC6 A;  1UEF A;  3KSY A;  2M38 A;  4HB2 B;  3KZ1 A;  3SYX A;  5DH9 B;  5CLQ B;  2EJ8 A;  3PVU A;  2VKI A;  1V5P A;  4K17 A;  4ZRJ A;  1U27 A;  2UVM A;  2DTC A;  5HE3 A;  3CIK A;  1NTY A;  2MFQ A;  1P5T A;  2Z0Q A;  3QBV B;  4XWX A;  4NSW A;  2CY5 A;  4GMX B;  2MDX A;  1RJ2 A;  2L1C A;  1W1G A;  3A8Q A;  1OQN A;  4GPT B;  5D27 A;  4HAW B;  1DYN A;  3GYP A;  5EFX A;  1P6S A;  2I1K A;  3TW1 A;  5C6R A;  1J0W A;  1FGZ A;  1EAZ A;  4KAX B;  3CXB B;  4TKN A;  5HE2 A;  2W2W A;  3PEG A;  2GCJ A;  3MDB C;  5C16 A;  1GC7 A;  4GXB A;  3FM8 C;  4YON A;  3FSS A;  2LG1 A;  5L81 A;  4IAP A;  1I7A A;  2YRY A;  2YF0 A;  1PMS A;  3F0W A;  4A6F B;  1N3H A;  1UPQ A;  1Q67 A;  2H7E A;  5DIF B;  5C5B A;  1U5G A;  1FB8 A;  5KQ4 A;  2D4Q A;  1TQZ A;  5J3Q A;  1V88 A;  1K5G B;  1V5M A;  3TFM A;  2HE7 A;  2DYQ A;  5CLL B;  1MK7 B;  4P7I A;  3PG7 A;  2XQN M;  4WSF A;  1TXD A;  3ULB A;  1XCG A;  4CYE A;  4KVG B;  2CRF A;  2DX5 A;  4B6H A;  5C79 A;  3P6A A;  2COD A;  2COC A;  4KHA A;  1NI2 A;  1UPR A;  3KRX A;  1U5D A;  2MKR A;  4IOY X;  3WA0 A;  4F7G A;  4EJN A;  5HE1 A;  2ELA A;  2X18 A;  1XD4 A;  5D3Y A;  2G35 A;  3PZD A;  5KQ1 A;  2L2I A;  3M1I B;  1XR0 B;  5J3Y A;  4HAT B;  2UZS A;  3BIN A;  1BTK A;  4GZU A;  2H7D A;  2I5F A;  5GOW B;  2W2X D;  2RUK B;  1FHW A;  3HK0 A;  3ZVR A;  4D0N B;  1MKE A;  3TO1 A;  4DX9 0;  2LUL A;  2GS0 A;  4L6E A;  2KGX B;  2NMB A;  2J0M A;  2I5C A;  1ISN A;  1FHO A;  4WJ7 A;  1XOD A;  3ODX A;  2V76 A;  2I1J A;  2MWN B;  2P0D A;  1ZSQ A;  2AEH A;  2RNR B;  3HW2 B;  1FAO A;  2J59 M;  2Z0O A;  4MT7 A;  2Q13 A;  1ZC3 B;  3TCA A;  3NSU A;  4EMO A;  3ML4 A;  3GYO A;  3ULC A;  2M14 A;  1LW3 A;  1LB1 A;  3IVF A;  4ZRI A;  1WJ1 A;  2K00 A;  1FOE A;  2D10 A;  1AWE A;  1X86 A;  5FI0 A;  1UNQ A;  4YL8 A;  3N7C A;  1NU2 A;  4KHB B;  2D2Q A;  1FGY A;  4DXA B;  4HAV B; 
#chains in the Genus database with same CATH topology
 5LON B;  4Z2N A;  4QJ5 B;  4H8S A;  1W1D A;  1SHC A;  2GUM A;  2YVC A;  3DXD A;  3WYF B;  2Y7B A;  3U7D A;  3U8Z A;  2E2X A;  3NW8 A;  4Y94 A;  3DXC A;  3PVW A;  3RCP A;  1OY2 A;  2NBV A;  3QIJ A;  4Z2M B;  1X11 A;  5D3V A;  3VIA A;  3SNH A;  3HQC A;  1RRP B;  2N23 A;  3KRW A;  1EF1 A;  4HAZ B;  3SUZ A;  4DBB A;  4HAY B;  4F7U P;  2GCL A;  2ROZ B;  2VRW B;  2D9W A;  2VSZ A;  1AQC A;  2DA0 A;  4K2O A;  2K8E A;  1V5U A;  5D3X A;  5DHA B;  4DX8 A;  2YS3 A;  1X1G A;  4CHJ A;  1U29 A;  4GMV A;  2ZPY A;  3PP2 A;  4A6F A;  2DX1 A;  4EKU A;  4C0A A;  1MAI A;  1K5D B;  2RVB B;  4PQ0 A;  3AU5 A;  2Z14 A;  3MPX A;  3A98 B;  5HE0 A;  2YT0 A;  1KZ7 A;  5D3W A;  1EGX A;  1U5E A;  2LOX A;  2J0J A;  2DHJ A;  1BTN A;  5J3T A;  2DHI A;  1BAK A;  2Y8F A;  1GG3 A;  2BCJ A;  2DHK A;  2IFS A;  2DKQ A;  1W1H A;  4BBK A;  4HB4 B;  2KIE A;  3D8F A;  1ZM0 A;  1ZVR A;  4NY0 A;  5KCV A;  3AJ4 A;  2EMT A;  1NTV A;  1BWN A;  2W2X C;  3UZT A;  1KZG A;  1PFJ A;  1SGH A;  2PZ1 A;  2DN6 A;  2Y8G A;  1IRS A;  2LOZ A;  1P3R A;  1DDM A;  2D9Y A;  1X1F A;  2P8V A;  4HB0 B;  5JLJ B;  1J19 A;  1T77 A;  2Z4D A;  1FHX A;  3QWM A;  4K2P A;  3KY9 A;  3PVL A;  4MY6 A;  3NWF A;  5I2S A;  1H4R A;  2D11 A;  2FJL A;  1E5W A;  4GNK B;  1UNP A;  1MIZ B;  2QKL A;  4ZRK A;  2N0Y A;  3BJI A;  1KI1 B;  1OMW A;  1DRO A;  1WG7 A;  3LJU X;  3ODO A;  4K81 A;  2RSG A;  5IRS A;  2RLO A;  1QC6 A;  3G9W A;  1QQG A;  4GN1 A;  2OQB A;  1WGU A;  4OT1 A;  4WVF B;  5JHH A;  2OTX A;  2JP2 A;  2J0K A;  3P7Z A;  4HHV A;  5JP4 A;  1V89 A;  4F7H A;  1M7E A;  2CAY A;  4HAU B;  1U2B A;  2YS1 A;  3SO6 A;  1MI1 A;  3F5R A;  5M4Y B;  4QJ4 B;  1WGQ A;  2DFK A;  3O96 A;  2HTH B;  3T06 A;  5LOP B;  1MPH A;  2YS5 A;  2COA A;  4KHB A;  5FI1 A;  4KHO A;  2GJY A;  4A6K A;  2ROV A;  2FJU B;  5C5B B;  2RRF A;  5DHF B;  3V5W A;  1Z87 A;  4PNK A;  3X23 A;  3NWD A;  2NZ8 B;  2KUP A;  4CHM A;  2RGN B;  2P0H A;  4A6H A;  1XKE A;  2CY4 A;  1DDV A;  3SV1 A;  2K2J A;  1TJ6 A;  3AU4 A;  2EC1 A;  3D8D A;  1DBH A;  3FVC A;  2YT1 A;  3PSC A;  2R0D A;  3HIE A;  2P0F A;  1H10 A;  4L1R A;  1Y19 B;  3D8E A;  1V61 A;  2COF A;  5JHG A;  2ELB A;  1I2H A;  2DLW A;  4D6W A;  2ADZ A;  2LKO A;  2Z59 A;  3FEH A;  3A8P A;  2UZR A;  2EMS A;  3ZDT A;  2DKP A;  2K2U A;  2Z0P A;  1U5F A;  4IFS A;  1X05 A;  1MK9 B;  2D9X A;  2K49 A;  2KUQ A;  4MK0 A;  2R09 A;  1UNR A;  4HAX B;  1M7R A;  2IYB A;  1PLS A;  2LYD A;  1ZC4 B;  1WVH A;  2QKM A;  4HDQ A;  2D9Z A;  4OSN A;  1EVH A;  1WI1 A;  2KCJ A;  3DXE A;  2YSZ A;  1MIX A;  2AL6 A;  4HB3 B;  3TVV A;  1DDW A;  2DYN A;  1B55 A;  1Y5O A;  4A5K A;  3VOQ A;  3OAN A;  4HSI A;  1WJM A;  4QJ3 B;  4TYZ A;  3NWA A;  5DI9 B;  3ODW A;  2D9V A;  1XX0 A;  4HDO A;  1GC6 A;  1UEF A;  3KSY A;  2M38 A;  4HB2 B;  3KZ1 A;  3SYX A;  5DH9 B;  5CLQ B;  2EJ8 A;  3PVU A;  2VKI A;  1V5P A;  4K17 A;  4ZRJ A;  1U27 A;  2UVM A;  2DTC A;  5HE3 A;  3CIK A;  1NTY A;  2MFQ A;  1P5T A;  2Z0Q A;  3QBV B;  4XWX A;  4NSW A;  2CY5 A;  4GMX B;  2MDX A;  1RJ2 A;  2L1C A;  1W1G A;  3A8Q A;  1OQN A;  4GPT B;  5D27 A;  4HAW B;  4DIX A;  1DYN A;  3GYP A;  5EFX A;  1P6S A;  2I1K A;  3TW1 A;  5C6R A;  1J0W A;  1FGZ A;  1EAZ A;  4KAX B;  3CXB B;  4TKN A;  5HE2 A;  2W2W A;  3PEG A;  2GCJ A;  3MDB C;  5C16 A;  1GC7 A;  2Z13 A;  4GXB A;  3FM8 C;  4YON A;  3FSS A;  2LG1 A;  5L81 A;  4IAP A;  1I7A A;  2YRY A;  2YF0 A;  1PMS A;  3F0W A;  4A6F B;  1N3H A;  1UPQ A;  2R2Y A;  1Q67 A;  2H7E A;  5DIF B;  5C5B A;  1U5G A;  1FB8 A;  3OHM B;  5LG4 B;  5KQ4 A;  2D4Q A;  1TQZ A;  5J3Q A;  1V88 A;  1K5G B;  1V5M A;  3B77 A;  3TFM A;  2HE7 A;  2DYQ A;  5CLL B;  1MK7 B;  4P7I A;  3PG7 A;  2XQN M;  4WSF A;  1TXD A;  3ULB A;  1XCG A;  4CYE A;  4KVG B;  2CRF A;  2ZKM X;  2DX5 A;  4B6H A;  5C79 A;  3P6A A;  4GOU A;  2COD A;  2COC A;  4KHA A;  1NI2 A;  1UPR A;  3KRX A;  1U5D A;  2MKR A;  4IOY X;  3WA0 A;  4F7G A;  4EJN A;  5HE1 A;  2ELA A;  1ZYI A;  2X18 A;  1XD4 A;  5D3Y A;  2G35 A;  3PZD A;  5KQ1 A;  2L2I A;  3M1I B;  1XR0 B;  5J3Y A;  2KR0 A;  4HAT B;  2UZS A;  3BIN A;  1BTK A;  4GZU A;  2H7D A;  2I5F A;  5GOW B;  2W2X D;  2RUK B;  3DCX A;  1FHW A;  3HK0 A;  5I2M A;  3ZVR A;  3A58 A;  4D0N B;  1MKE A;  3TO1 A;  4DX9 0;  2LUL A;  2GS0 A;  4L6E A;  2KGX B;  2NMB A;  2J0M A;  2I5C A;  1ISN A;  1FHO A;  4WJ7 A;  1XOD A;  3ODX A;  2V76 A;  2I1J A;  2MWN B;  2P0D A;  1ZSQ A;  2AEH A;  2YT2 A;  2RNR B;  3HW2 B;  1FAO A;  2J59 M;  2Z0O A;  4MT7 A;  2Q13 A;  1ZC3 B;  3TCA A;  3NSU A;  4CSQ A;  4EMO A;  3ML4 A;  3GYO A;  3ULC A;  2M14 A;  1LW3 A;  1LB1 A;  3IVF A;  2KIG A;  4ZRI A;  1WJ1 A;  2K00 A;  1FOE A;  2D10 A;  1AWE A;  1X86 A;  5FI0 A;  1UNQ A;  3U12 A;  4YL8 A;  3N7C A;  1NU2 A;  4KHB B;  3HSA A;  2D2Q A;  1FGY A;  4QXA B;  4DXA B;  4HAV B; 
#chains in the Genus database with same CATH homology
 5LON B;  4Z2N A;  4H8S A;  1W1D A;  1SHC A;  2YVC A;  3DXD A;  3WYF B;  2Y7B A;  3U7D A;  3U8Z A;  2E2X A;  4Y94 A;  3DXC A;  3PVW A;  3RCP A;  1OY2 A;  3QIJ A;  4Z2M B;  1X11 A;  5D3V A;  3VIA A;  3SNH A;  3HQC A;  1RRP B;  2N23 A;  3KRW A;  1EF1 A;  4HAZ B;  3SUZ A;  4DBB A;  4HAY B;  4F7U P;  2GCL A;  2ROZ B;  2VRW B;  2D9W A;  2VSZ A;  1AQC A;  2DA0 A;  4K2O A;  1V5U A;  5D3X A;  5DHA B;  4DX8 A;  2YS3 A;  1X1G A;  4CHJ A;  1U29 A;  4GMV A;  2ZPY A;  3PP2 A;  4A6F A;  2DX1 A;  4EKU A;  4C0A A;  1MAI A;  1K5D B;  2RVB B;  4PQ0 A;  3AU5 A;  3MPX A;  3A98 B;  5HE0 A;  2YT0 A;  1KZ7 A;  5D3W A;  1EGX A;  1U5E A;  2LOX A;  2J0J A;  2DHJ A;  1BTN A;  5J3T A;  2DHI A;  1BAK A;  2Y8F A;  1GG3 A;  2BCJ A;  2DHK A;  2IFS A;  2DKQ A;  1W1H A;  4BBK A;  4HB4 B;  3D8F A;  1ZM0 A;  1ZVR A;  4NY0 A;  5KCV A;  3AJ4 A;  2EMT A;  1NTV A;  1BWN A;  2W2X C;  3UZT A;  1KZG A;  1PFJ A;  1SGH A;  2PZ1 A;  2DN6 A;  2Y8G A;  1IRS A;  2LOZ A;  1P3R A;  1DDM A;  2D9Y A;  1X1F A;  2P8V A;  4HB0 B;  5JLJ B;  1J19 A;  1FHX A;  3QWM A;  4K2P A;  3KY9 A;  3PVL A;  4MY6 A;  1H4R A;  2D11 A;  2FJL A;  1E5W A;  1UNP A;  1MIZ B;  2QKL A;  4ZRK A;  2N0Y A;  3BJI A;  1KI1 B;  1OMW A;  1DRO A;  1WG7 A;  3LJU X;  3ODO A;  4K81 A;  2RSG A;  2RLO A;  1QC6 A;  3G9W A;  1QQG A;  4GN1 A;  2OQB A;  1WGU A;  4WVF B;  5JHH A;  2OTX A;  2JP2 A;  2J0K A;  3P7Z A;  4HHV A;  5JP4 A;  1V89 A;  4F7H A;  1M7E A;  2CAY A;  4HAU B;  1U2B A;  2YS1 A;  3SO6 A;  3F5R A;  1WGQ A;  2DFK A;  3O96 A;  2HTH B;  3T06 A;  5LOP B;  1MPH A;  2YS5 A;  2COA A;  5FI1 A;  4KHO A;  2GJY A;  4A6K A;  2ROV A;  5C5B B;  5DHF B;  3V5W A;  1Z87 A;  4PNK A;  3X23 A;  2NZ8 B;  2KUP A;  4CHM A;  2RGN B;  2P0H A;  4A6H A;  1XKE A;  2CY4 A;  1DDV A;  3SV1 A;  2K2J A;  1TJ6 A;  3AU4 A;  2EC1 A;  3D8D A;  1DBH A;  2YT1 A;  3PSC A;  2R0D A;  2P0F A;  1H10 A;  1Y19 B;  3D8E A;  1V61 A;  2COF A;  5JHG A;  2ELB A;  1I2H A;  2DLW A;  2ADZ A;  2LKO A;  3FEH A;  3A8P A;  2UZR A;  2EMS A;  3ZDT A;  2DKP A;  2K2U A;  2Z0P A;  1U5F A;  4IFS A;  1X05 A;  1MK9 B;  2D9X A;  4MK0 A;  2R09 A;  1UNR A;  4HAX B;  1M7R A;  2IYB A;  1PLS A;  2LYD A;  1ZC4 B;  1WVH A;  2QKM A;  4HDQ A;  2D9Z A;  1EVH A;  1WI1 A;  2KCJ A;  3DXE A;  2YSZ A;  1MIX A;  2AL6 A;  4HB3 B;  3TVV A;  1DDW A;  2DYN A;  1B55 A;  1Y5O A;  4A5K A;  3VOQ A;  3OAN A;  1WJM A;  4TYZ A;  5DI9 B;  3ODW A;  2D9V A;  1XX0 A;  4HDO A;  1GC6 A;  1UEF A;  3KSY A;  2M38 A;  4HB2 B;  3KZ1 A;  3SYX A;  5DH9 B;  5CLQ B;  2EJ8 A;  3PVU A;  2VKI A;  1V5P A;  4K17 A;  4ZRJ A;  1U27 A;  2UVM A;  2DTC A;  5HE3 A;  3CIK A;  1NTY A;  2MFQ A;  1P5T A;  2Z0Q A;  3QBV B;  4XWX A;  4NSW A;  2CY5 A;  4GMX B;  2MDX A;  1RJ2 A;  2L1C A;  1W1G A;  3A8Q A;  1OQN A;  4GPT B;  5D27 A;  4HAW B;  1DYN A;  3GYP A;  5EFX A;  1P6S A;  2I1K A;  3TW1 A;  5C6R A;  1J0W A;  1FGZ A;  1EAZ A;  4KAX B;  3CXB B;  4TKN A;  5HE2 A;  2W2W A;  3PEG A;  2GCJ A;  3MDB C;  5C16 A;  1GC7 A;  4GXB A;  3FM8 C;  4YON A;  3FSS A;  2LG1 A;  5L81 A;  4IAP A;  1I7A A;  2YRY A;  2YF0 A;  1PMS A;  3F0W A;  4A6F B;  1N3H A;  1UPQ A;  1Q67 A;  2H7E A;  5DIF B;  5C5B A;  1U5G A;  1FB8 A;  5KQ4 A;  2D4Q A;  1TQZ A;  5J3Q A;  1V88 A;  1K5G B;  1V5M A;  3TFM A;  2HE7 A;  2DYQ A;  5CLL B;  1MK7 B;  4P7I A;  3PG7 A;  2XQN M;  4WSF A;  1TXD A;  3ULB A;  1XCG A;  4CYE A;  4KVG B;  2CRF A;  2DX5 A;  4B6H A;  5C79 A;  3P6A A;  2COD A;  2COC A;  4KHA A;  1NI2 A;  1UPR A;  3KRX A;  1U5D A;  2MKR A;  4IOY X;  3WA0 A;  4F7G A;  4EJN A;  5HE1 A;  2ELA A;  2X18 A;  1XD4 A;  5D3Y A;  2G35 A;  3PZD A;  5KQ1 A;  2L2I A;  3M1I B;  1XR0 B;  5J3Y A;  4HAT B;  2UZS A;  3BIN A;  1BTK A;  4GZU A;  2H7D A;  2I5F A;  5GOW B;  2W2X D;  2RUK B;  1FHW A;  3HK0 A;  3ZVR A;  4D0N B;  1MKE A;  3TO1 A;  4DX9 0;  2LUL A;  2GS0 A;  4L6E A;  2KGX B;  2NMB A;  2J0M A;  2I5C A;  1ISN A;  1FHO A;  4WJ7 A;  1XOD A;  3ODX A;  2V76 A;  2I1J A;  2MWN B;  2P0D A;  1ZSQ A;  2AEH A;  2RNR B;  3HW2 B;  1FAO A;  2J59 M;  2Z0O A;  4MT7 A;  2Q13 A;  1ZC3 B;  3TCA A;  3NSU A;  4EMO A;  3ML4 A;  3GYO A;  3ULC A;  2M14 A;  1LW3 A;  1LB1 A;  3IVF A;  4ZRI A;  1WJ1 A;  2K00 A;  1FOE A;  2D10 A;  1AWE A;  1X86 A;  5FI0 A;  1UNQ A;  4YL8 A;  3N7C A;  1NU2 A;  4KHB B;  2D2Q A;  1FGY A;  4DXA B;  4HAV B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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