4EMOA

Crystal structure of the ph domain of sharpin
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
104
structure length
104
Chain Sequence
AAVLMAVHAAVRPLGAGPDAEAQLRRLQLSADPERPGRFRLELLGAGPGAVNLEWPLESVSYTIRGPTQHELQPPPGGPGTLSMHFLNPQEAQRWAVLVRGATV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Analysis of SHARPIN, a Subunit of a Large Multi-protein E3 Ubiquitin Ligase, Reveals a Novel Dimerization Function for the Pleckstrin Homology Superfold.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Sharpin
total genus 19
structure length 104
sequence length 104
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2012-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16764 Sharpin_PH Sharpin PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 4emoA00
2I1KA 4NSWA 3DXDA 4ZRIA 2KCJA 4MT7A 2MFQA 1PFJA 4GXBA 3AU5A 1WG7A 4HAYB 1XX0A 4H8SA 3O96A 2EJ8A 3OANA 1X86A 2RGNB 2YSZA 2DKQA 2BCJA 1DDMA 1M7RA 1ISNA 1UEFA 2LOZA 4CYEA 4YONA 2D2QA 5LOPB 2DYQA 1PMSA 3QIJA 1LW3A 4HHVA 1Y19B 1FHXA 1KZGA 4GZUA 2G35A 5J3QA 2YS1A 3N7CA 4HB2B 2COFA 3D8FA 1PLSA 2P0DA 2RUKB 2VRWB 2ZPYA 1V89A 2EMTA 1X1FA 2DLWA 1KI1B 1V5UA 3U7DA 2UVMA 2I5FA 4K2PA 3WA0A 3KY9A 1WJMA 5HE2A 1XD4A 2DA0A 3DXCA 4ZRJA 1AQCA 3GYOA 1DROA 2L1CA 3SYXA 1FHOA 1WGQA 2VKIA 1WVHA 2EMSA 5DH9B 2X18A 4KVGB 1B55A 1V88A 1P3RA 3TCAA 3PG7A 3RCPA 1MPHA 2RSGA 4KHAA 2K2UA 2DX1A 2GCLA 2CY5A 2PZ1A 3ODWA 5GOWB 2ELBA 2P0FA 4EJNA 4HDQA 2Y8GA 3DXEA 1OQNA 4NY0A 3ZVRA 1FAOA 1EAZA 1FHWA 1Q67A 2K00A 4IFSA 1J19A 1DDWA 1I2HA 5DIFB 5HE1A 4HDOA 2ELAA 2V76A 4HAXB 1BWNA 1V61A 1TXDA 3X23A 2DKPA 3KRWA 1DDVA 4F7GA 2D4QA 4GMVA 2J59M 2CRFA 2MDXA 1MAIA 2H7EA 3UZTA 3D8DA 1DBHA 5JLJB 5KQ4A 1RJ2A 1NU2A 2H7DA 1FB8A 1FOEA 4HB3B 2DYNA 3A98B 3KZ1A 4GMXB 1NI2A 2UZRA 4CHJA 2QKLA 4KHOA 2J0JA 3T06A 3TFMA 2OQBA 1BAKA 1U5EA 3PEGA 1WJ1A 3FSSA 2D9YA 4Z2NA 3PSCA 3SUZA 4EMOA 4WSFA 5LONB 4A6HA 4PQ0A 5J3YA 2Y7BA 2UZSA 4K17A 3SV1A 5C5BA 4EKUA 2VSZA 2DHJA 3FM8C 4A6FA 2Y8FA 5JHHA 3HQCA 4KHBB 1IRSA 1TJ6A 1MK7B 5DI9B 1MK9B 1UPRA 4K81A 1Y5OA 4WJ7A 2M38A 1TQZA 2M14A 3QBVB 2Z0QA 4GPTB 2I5CA 2D9VA 2JP2A 2LOXA 1W1GA 2R0DA 1SGHA 4K2OA 4MK0A 2HE7A 3MPXA 1MKEA 2ROVA 1XR0B 2IFSA 2N0YA 3G9WA 2MWNB 1H4RA 5L81A 4HB0B 1XODA 3CXBB 4HAZB 5KQ1A 3KRXA 3A8QA 3ULCA 1X05A 4YL8A 2Z0PA 1U5FA 2N23A 4WVFB 3TVVA 3GYPA 1SHCA 5DHFB 2J0MA 2AEHA 2RVBB 3AJ4A 4DX8A 5D27A 1AWEA 1W1DA 1ZC4B 1U5DA 3FEHA 1ZM0A 2OTXA 2YRYA 3MDBC 4C0AA 5KCVA 4IAPA 3HK0A 4A6FB 1I7AA 2YT0A 1DYNA 1U2BA 3PVWA 2IYBA 1UNPA 2NMBA 1ZC3B 3PZDA 3BINA 4Z2MB 1XKEA 2CAYA 2ADZA 2LKOA 2YF0A 3ML4A 1V5PA 2HTHB 5J3TA 3IVFA 3PVLA 4MY6A 5C79A 5JP4A 3PVUA 1FGYA 3ODXA 4GN1A 2QKMA 4ZRKA 1EGXA 1N3HA 2RNRB 3ZDTA 1QC6A 1KZ7A 2LULA 4XWXA 5EFXA 2Z0OA 2P0HA 2E2XA 2EC1A 2ROZB 2DHIA 2XQNM 1X11A 1BTKA 1W1HA 3A8PA 4Y94A 3P6AA 4HATB 1U27A 2DTCA 5D3VA 2DFKA 2LYDA 3ULBA 1UNRA 2R09A 5D3YA 4D0NB 3VOQA 1OMWA 2CODA 1MIXA 1LB1A 2AL6A 1QQGA 1J0WA 1P5TA 3ODOA 4PNKA 3TW1A 2LG1A 4TYZA 4KAXB 2RLOA 4L6EA 1UNQA 5C16A 3PP2A 1ZVRA 2YVCA 3KSYA 1BTNA 3SO6A 3AU4A 1GC6A 2MKRA 2KGXB 4HAVB 4B6HA 4A6KA 3P7ZA 1NTVA 1U5GA 3F0WA 5CLLB 5DHAB 4IOYX 5HE3A 1Z87A 3NSUA 1RRPB 4HAUB 1U29A 2D11A 4TKNA 4HB4B 2DN6A 3F5RA 3U8ZA 3WYFB 2DHKA 2KUPA 2CY4A 4HAWB 1XCGA 2P8VA 1X1GA 3LJUX 1GG3A 4P7IA 1K5GB 2YT1A 5FI0A 4DX90 2YS3A 2COAA 1UPQA 4F7HA 5HE0A 5FI1A 2J0KA 5C5BB 1OY2A 3BJIA 5JHGA 2GJYA 1WI1A 3M1IB 4F7UP 2W2WA 2DX5A 1EVHA 2FJLA 4CHMA 1EF1A 5D3WA 2D9XA 2D9ZA 3QWMA 2YS5A 1WGUA 4DXAB 1E5WA 2D9WA 1FGZA 5D3XA 2Q13A 3HW2B 1GC7A 2NZ8B 4BBKA 1P6SA 3SNHA 3V5WA 5C6RA 1M7EA 3D8EA 4DBBA 2W2XD 5CLQB 3TO1A 1K5DB 4A5KA 1NTYA 2D10A 2W2XC 1ZSQA 2I1JA 3VIAA 1H10A 1V5MA 2GS0A 3CIKA 2GCJA 1MIZB 2K2JA 2L2IA 2COCA
chains in the Genus database with same CATH superfamily
2I1KA 4NSWA 3DXDA 4ZRIA 2KCJA 4MT7A 2MFQA 1PFJA 3B77A 4GXBA 3AU5A 3NWAA 5LG4B 1WG7A 4HAYB 1XX0A 4H8SA 3O96A 2EJ8A 3OANA 1X86A 2RGNB 2YSZA 2DKQA 2BCJA 1DDMA 1M7RA 1ISNA 1UEFA 2LOZA 4CYEA 4YONA 2D2QA 2R2YA 5LOPB 2DYQA 1PMSA 3QIJA 1LW3A 4HHVA 3U12A 1Y19B 1FHXA 1KZGA 4GZUA 2G35A 5J3QA 2YS1A 2Z59A 3N7CA 2K8EA 4HB2B 2COFA 3D8FA 1PLSA 2P0DA 2RUKB 2VRWB 2ZPYA 1V89A 2EMTA 1X1FA 2DLWA 5I2SA 1KI1B 1V5UA 1ZYIA 2UVMA 3U7DA 1MI1A 2I5FA 4K2PA 3WA0A 3KY9A 1WJMA 5HE2A 1XD4A 2DA0A 3DXCA 4ZRJA 1AQCA 3GYOA 1DROA 2L1CA 3SYXA 1FHOA 1WGQA 2VKIA 1WVHA 2EMSA 5DH9B 2X18A 4KVGB 1B55A 3HSAA 1V88A 4DIXA 1P3RA 3TCAA 3PG7A 3RCPA 1MPHA 2RSGA 4KHAA 2K2UA 2DX1A 2GCLA 2CY5A 2PZ1A 3ODWA 5GOWB 2ELBA 2P0FA 4EJNA 4HDQA 2Z13A 3NW8A 4D6WA 2Y8GA 3DXEA 5M4YB 1OQNA 4NY0A 3ZVRA 1FAOA 1EAZA 1FHWA 1Q67A 2K00A 4GOUA 4IFSA 1J19A 4QJ5B 1DDWA 1I2HA 4OT1A 5DIFB 4HDOA 2ELAA 2V76A 5HE1A 4HAXB 1BWNA 1V61A 1TXDA 3X23A 2DKPA 3KRWA 1DDVA 4F7GA 2D4QA 4GMVA 4QJ4B 2J59M 2CRFA 2MDXA 1MAIA 2H7EA 3UZTA 3D8DA 1DBHA 5JLJB 5KQ4A 1RJ2A 1NU2A 2H7DA 1FB8A 1FOEA 4HB3B 2DYNA 3A98B 4QXAB 3KZ1A 4GMXB 1NI2A 2UZRA 4CHJA 2QKLA 4KHOA 2J0JA 3T06A 3TFMA 2OQBA 1BAKA 1U5EA 3PEGA 1WJ1A 3FSSA 2D9YA 4Z2NA 3PSCA 3SUZA 4EMOA 4WSFA 5LONB 4A6HA 2GUMA 4PQ0A 5J3YA 2Y7BA 2UZSA 4K17A 3SV1A 5C5BA 4EKUA 2VSZA 2DHJA 3FM8C 4A6FA 2Y8FA 5JHHA 3HQCA 2RRFA 4KHBB 1IRSA 1TJ6A 1MK7B 4QJ3B 5DI9B 1MK9B 1UPRA 4K81A 1Y5OA 4WJ7A 2M38A 1TQZA 2M14A 3QBVB 2Z0QA 4GPTB 2NBVA 2I5CA 2D9VA 2JP2A 2LOXA 1W1GA 2R0DA 1SGHA 4K2OA 4MK0A 2HE7A 3MPXA 1MKEA 2ROVA 1XR0B 2IFSA 2N0YA 3G9WA 2MWNB 1H4RA 5L81A 4HB0B 1XODA 3CXBB 4HAZB 5KQ1A 3KRXA 5I2MA 3A8QA 3ULCA 1X05A 4YL8A 2YT2A 2Z0PA 4GNKB 1U5FA 2N23A 4WVFB 1T77A 3TVVA 3GYPA 1SHCA 5DHFB 2J0MA 2AEHA 2RVBB 3AJ4A 4DX8A 5D27A 1AWEA 1W1DA 1ZC4B 1U5DA 3FEHA 1ZM0A 2OTXA 2YRYA 3MDBC 4C0AA 5KCVA 4IAPA 2KIEA 3HK0A 4A6FB 1I7AA 2YT0A 1DYNA 1U2BA 3PVWA 2IYBA 1UNPA 2NMBA 3DCXA 3OHMB 1ZC3B 3PZDA 3BINA 4Z2MB 1XKEA 2CAYA 2ADZA 2LKOA 2YF0A 3ML4A 1V5PA 2Z4DA 2HTHB 5J3TA 3IVFA 3PVLA 4MY6A 5C79A 5JP4A 3PVUA 1FGYA 3ODXA 4GN1A 2QKMA 4ZRKA 1EGXA 1N3HA 2RNRB 3ZDTA 1QC6A 1KZ7A 2LULA 4XWXA 5EFXA 2Z0OA 2P0HA 2E2XA 2EC1A 3NWDA 2FJUB 2ROZB 2DHIA 2XQNM 1X11A 1BTKA 3HIEA 4OSNA 1W1HA 3A8PA 4Y94A 3P6AA 2KR0A 4HATB 1U27A 2DTCA 5D3VA 2DFKA 2LYDA 3ULBA 1UNRA 2R09A 2Z14A 5D3YA 4D0NB 3VOQA 1OMWA 2CODA 1MIXA 1LB1A 2AL6A 1QQGA 2K49A 1J0WA 1P5TA 3ODOA 4PNKA 3NWFA 3TW1A 2LG1A 4TYZA 4KAXB 2RLOA 4L6EA 2KUQA 1UNQA 5C16A 3PP2A 1ZVRA 2YVCA 3KSYA 1BTNA 3SO6A 3AU4A 1GC6A 2MKRA 2KGXB 4HAVB 4B6HA 4HSIA 4A6KA 3P7ZA 1NTVA 1U5GA 3F0WA 5CLLB 5DHAB 4IOYX 5HE3A 4CSQA 1Z87A 3NSUA 1RRPB 4HAUB 1U29A 2D11A 4TKNA 4HB4B 2DN6A 3F5RA 3U8ZA 3WYFB 2DHKA 2KUPA 2CY4A 4HAWB 1XCGA 2P8VA 1X1GA 3LJUX 1GG3A 4P7IA 1K5GB 2YT1A 5FI0A 4DX90 2YS3A 2COAA 1UPQA 4F7HA 5HE0A 5FI1A 2J0KA 5C5BB 1OY2A 3BJIA 5JHGA 2GJYA 1WI1A 3M1IB 4F7UP 2W2WA 3A58A 2DX5A 4KHBA 1EVHA 2FJLA 4CHMA 1EF1A 5D3WA 2D9XA 2D9ZA 3QWMA 2YS5A 1WGUA 4DXAB 1E5WA 2D9WA 1FGZA 4L1RA 5D3XA 2Q13A 3HW2B 2KIGA 1GC7A 2NZ8B 5IRSA 2ZKMX 4BBKA 1P6SA 3SNHA 3V5WA 5C6RA 3D8EA 1M7EA 3FVCA 4DBBA 2W2XD 5CLQB 3TO1A 1K5DB 4A5KA 1NTYA 2D10A 2W2XC 1ZSQA 2I1JA 3VIAA 1H10A 1V5MA 2GS0A 3CIKA 2GCJA 1MIZB 2K2JA 2L2IA 2COCA
chains in the Genus database with same CATH topology
2I1KA 4NSWA 3DXDA 4ZRIA 2KCJA 4MT7A 2MFQA 1PFJA 4GXBA 3AU5A 1WG7A 4HAYB 1XX0A 4H8SA 3O96A 2EJ8A 3OANA 1X86A 2RGNB 2YSZA 2DKQA 2BCJA 1DDMA 1M7RA 1ISNA 1UEFA 2LOZA 4CYEA 4YONA 2D2QA 5LOPB 2DYQA 1PMSA 3QIJA 1LW3A 4HHVA 1Y19B 1FHXA 1KZGA 4GZUA 2G35A 5J3QA 2YS1A 3N7CA 4HB2B 2COFA 3D8FA 1PLSA 2P0DA 2RUKB 2VRWB 2ZPYA 1V89A 2EMTA 1X1FA 2DLWA 1KI1B 1V5UA 3U7DA 2UVMA 2I5FA 4K2PA 3WA0A 3KY9A 1WJMA 5HE2A 1XD4A 2DA0A 3DXCA 4ZRJA 1AQCA 3GYOA 1DROA 2L1CA 3SYXA 1FHOA 1WGQA 2VKIA 1WVHA 2EMSA 5DH9B 2X18A 4KVGB 1B55A 1V88A 1P3RA 3TCAA 3PG7A 3RCPA 1MPHA 2RSGA 4KHAA 2K2UA 2DX1A 2GCLA 2CY5A 2PZ1A 3ODWA 5GOWB 2ELBA 2P0FA 4EJNA 4HDQA 2Y8GA 3DXEA 1OQNA 4NY0A 3ZVRA 1FAOA 1EAZA 1FHWA 1Q67A 2K00A 4IFSA 1J19A 1DDWA 1I2HA 5DIFB 5HE1A 4HDOA 2ELAA 2V76A 4HAXB 1BWNA 1V61A 1TXDA 3X23A 2DKPA 3KRWA 1DDVA 4F7GA 2D4QA 4GMVA 2J59M 2CRFA 2MDXA 1MAIA 2H7EA 3UZTA 3D8DA 1DBHA 5JLJB 5KQ4A 1RJ2A 1NU2A 2H7DA 1FB8A 1FOEA 4HB3B 2DYNA 3A98B 3KZ1A 4GMXB 1NI2A 2UZRA 4CHJA 2QKLA 4KHOA 2J0JA 3T06A 3TFMA 2OQBA 1BAKA 1U5EA 3PEGA 1WJ1A 3FSSA 2D9YA 4Z2NA 3PSCA 3SUZA 4EMOA 4WSFA 5LONB 4A6HA 4PQ0A 5J3YA 2Y7BA 2UZSA 4K17A 3SV1A 5C5BA 4EKUA 2VSZA 2DHJA 3FM8C 4A6FA 2Y8FA 5JHHA 3HQCA 4KHBB 1IRSA 1TJ6A 1MK7B 5DI9B 1MK9B 1UPRA 4K81A 1Y5OA 4WJ7A 2M38A 1TQZA 2M14A 3QBVB 2Z0QA 4GPTB 2I5CA 2D9VA 2JP2A 2LOXA 1W1GA 2R0DA 1SGHA 4K2OA 4MK0A 2HE7A 3MPXA 1MKEA 2ROVA 1XR0B 2IFSA 2N0YA 3G9WA 2MWNB 1H4RA 5L81A 4HB0B 1XODA 3CXBB 4HAZB 5KQ1A 3KRXA 3A8QA 3ULCA 1X05A 4YL8A 2Z0PA 1U5FA 2N23A 4WVFB 3TVVA 3GYPA 1SHCA 5DHFB 2J0MA 2AEHA 2RVBB 3AJ4A 4DX8A 5D27A 1AWEA 1W1DA 1ZC4B 1U5DA 3FEHA 1ZM0A 2OTXA 2YRYA 3MDBC 4C0AA 5KCVA 4IAPA 3HK0A 4A6FB 1I7AA 2YT0A 1DYNA 1U2BA 3PVWA 2IYBA 1UNPA 2NMBA 1ZC3B 3PZDA 3BINA 4Z2MB 1XKEA 2CAYA 2ADZA 2LKOA 2YF0A 3ML4A 1V5PA 2HTHB 5J3TA 3IVFA 3PVLA 4MY6A 5C79A 5JP4A 3PVUA 1FGYA 3ODXA 4GN1A 2QKMA 4ZRKA 1EGXA 1N3HA 2RNRB 3ZDTA 1QC6A 1KZ7A 2LULA 4XWXA 5EFXA 2Z0OA 2P0HA 2E2XA 2EC1A 2ROZB 2DHIA 2XQNM 1X11A 1BTKA 1W1HA 3A8PA 4Y94A 3P6AA 4HATB 1U27A 2DTCA 5D3VA 2DFKA 2LYDA 3ULBA 1UNRA 2R09A 5D3YA 4D0NB 3VOQA 1OMWA 2CODA 1MIXA 1LB1A 2AL6A 1QQGA 1J0WA 1P5TA 3ODOA 4PNKA 3TW1A 2LG1A 4TYZA 4KAXB 2RLOA 4L6EA 1UNQA 5C16A 3PP2A 1ZVRA 2YVCA 3KSYA 1BTNA 3SO6A 3AU4A 1GC6A 2MKRA 2KGXB 4HAVB 4B6HA 4A6KA 3P7ZA 1NTVA 1U5GA 3F0WA 5CLLB 5DHAB 4IOYX 5HE3A 1Z87A 3NSUA 1RRPB 4HAUB 1U29A 2D11A 4TKNA 4HB4B 2DN6A 3F5RA 3U8ZA 3WYFB 2DHKA 2KUPA 2CY4A 4HAWB 1XCGA 2P8VA 1X1GA 3LJUX 1GG3A 4P7IA 1K5GB 2YT1A 5FI0A 4DX90 2YS3A 2COAA 1UPQA 4F7HA 5HE0A 5FI1A 2J0KA 5C5BB 1OY2A 3BJIA 5JHGA 2GJYA 1WI1A 3M1IB 4F7UP 2W2WA 2DX5A 1EVHA 2FJLA 4CHMA 1EF1A 5D3WA 2D9XA 2D9ZA 3QWMA 2YS5A 1WGUA 4DXAB 1E5WA 2D9WA 1FGZA 5D3XA 2Q13A 3HW2B 1GC7A 2NZ8B 4BBKA 1P6SA 3SNHA 3V5WA 5C6RA 1M7EA 3D8EA 4DBBA 2W2XD 5CLQB 3TO1A 1K5DB 4A5KA 1NTYA 2D10A 2W2XC 1ZSQA 2I1JA 3VIAA 1H10A 1V5MA 2GS0A 3CIKA 2GCJA 1MIZB 2K2JA 2L2IA 2COCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I1K A;  4NSW A;  3DXD A;  4ZRI A;  2KCJ A;  4MT7 A;  2MFQ A;  1PFJ A;  4GXB A;  3AU5 A;  1WG7 A;  4HAY B;  1XX0 A;  4H8S A;  3O96 A;  2EJ8 A;  3OAN A;  1X86 A;  2RGN B;  2YSZ A;  2DKQ A;  2BCJ A;  1DDM A;  1M7R A;  1ISN A;  1UEF A;  2LOZ A;  4CYE A;  4YON A;  2D2Q A;  5LOP B;  2DYQ A;  1PMS A;  3QIJ A;  1LW3 A;  4HHV A;  1Y19 B;  1FHX A;  1KZG A;  4GZU A;  2G35 A;  5J3Q A;  2YS1 A;  3N7C A;  4HB2 B;  2COF A;  3D8F A;  1PLS A;  2P0D A;  2RUK B;  2VRW B;  2ZPY A;  1V89 A;  2EMT A;  1X1F A;  2DLW A;  1KI1 B;  1V5U A;  3U7D A;  2UVM A;  2I5F A;  4K2P A;  3WA0 A;  3KY9 A;  1WJM A;  5HE2 A;  1XD4 A;  2DA0 A;  3DXC A;  4ZRJ A;  1AQC A;  3GYO A;  1DRO A;  2L1C A;  3SYX A;  1FHO A;  1WGQ A;  2VKI A;  1WVH A;  2EMS A;  5DH9 B;  2X18 A;  4KVG B;  1B55 A;  1V88 A;  1P3R A;  3TCA A;  3PG7 A;  3RCP A;  1MPH A;  2RSG A;  4KHA A;  2K2U A;  2DX1 A;  2GCL A;  2CY5 A;  2PZ1 A;  3ODW A;  5GOW B;  2ELB A;  2P0F A;  4EJN A;  4HDQ A;  2Y8G A;  3DXE A;  1OQN A;  4NY0 A;  3ZVR A;  1FAO A;  1EAZ A;  1FHW A;  1Q67 A;  2K00 A;  4IFS A;  1J19 A;  1DDW A;  1I2H A;  5DIF B;  5HE1 A;  4HDO A;  2ELA A;  2V76 A;  4HAX B;  1BWN A;  1V61 A;  1TXD A;  3X23 A;  2DKP A;  3KRW A;  1DDV A;  4F7G A;  2D4Q A;  4GMV A;  2J59 M;  2CRF A;  2MDX A;  1MAI A;  2H7E A;  3UZT A;  3D8D A;  1DBH A;  5JLJ B;  5KQ4 A;  1RJ2 A;  1NU2 A;  2H7D A;  1FB8 A;  1FOE A;  4HB3 B;  2DYN A;  3A98 B;  3KZ1 A;  4GMX B;  1NI2 A;  2UZR A;  4CHJ A;  2QKL A;  4KHO A;  2J0J A;  3T06 A;  3TFM A;  2OQB A;  1BAK A;  1U5E A;  3PEG A;  1WJ1 A;  3FSS A;  2D9Y A;  4Z2N A;  3PSC A;  3SUZ A;  4EMO A;  4WSF A;  5LON B;  4A6H A;  4PQ0 A;  5J3Y A;  2Y7B A;  2UZS A;  4K17 A;  3SV1 A;  5C5B A;  4EKU A;  2VSZ A;  2DHJ A;  3FM8 C;  4A6F A;  2Y8F A;  5JHH A;  3HQC A;  4KHB B;  1IRS A;  1TJ6 A;  1MK7 B;  5DI9 B;  1MK9 B;  1UPR A;  4K81 A;  1Y5O A;  4WJ7 A;  2M38 A;  1TQZ A;  2M14 A;  3QBV B;  2Z0Q A;  4GPT B;  2I5C A;  2D9V A;  2JP2 A;  2LOX A;  1W1G A;  2R0D A;  1SGH A;  4K2O A;  4MK0 A;  2HE7 A;  3MPX A;  1MKE A;  2ROV A;  1XR0 B;  2IFS A;  2N0Y A;  3G9W A;  2MWN B;  1H4R A;  5L81 A;  4HB0 B;  1XOD A;  3CXB B;  4HAZ B;  5KQ1 A;  3KRX A;  3A8Q A;  3ULC A;  1X05 A;  4YL8 A;  2Z0P A;  1U5F A;  2N23 A;  4WVF B;  3TVV A;  3GYP A;  1SHC A;  5DHF B;  2J0M A;  2AEH A;  2RVB B;  3AJ4 A;  4DX8 A;  5D27 A;  1AWE A;  1W1D A;  1ZC4 B;  1U5D A;  3FEH A;  1ZM0 A;  2OTX A;  2YRY A;  3MDB C;  4C0A A;  5KCV A;  4IAP A;  3HK0 A;  4A6F B;  1I7A A;  2YT0 A;  1DYN A;  1U2B A;  3PVW A;  2IYB A;  1UNP A;  2NMB A;  1ZC3 B;  3PZD A;  3BIN A;  4Z2M B;  1XKE A;  2CAY A;  2ADZ A;  2LKO A;  2YF0 A;  3ML4 A;  1V5P A;  2HTH B;  5J3T A;  3IVF A;  3PVL A;  4MY6 A;  5C79 A;  5JP4 A;  3PVU A;  1FGY A;  3ODX A;  4GN1 A;  2QKM A;  4ZRK A;  1EGX A;  1N3H A;  2RNR B;  3ZDT A;  1QC6 A;  1KZ7 A;  2LUL A;  4XWX A;  5EFX A;  2Z0O A;  2P0H A;  2E2X A;  2EC1 A;  2ROZ B;  2DHI A;  2XQN M;  1X11 A;  1BTK A;  1W1H A;  3A8P A;  4Y94 A;  3P6A A;  4HAT B;  1U27 A;  2DTC A;  5D3V A;  2DFK A;  2LYD A;  3ULB A;  1UNR A;  2R09 A;  5D3Y A;  4D0N B;  3VOQ A;  1OMW A;  2COD A;  1MIX A;  1LB1 A;  2AL6 A;  1QQG A;  1J0W A;  1P5T A;  3ODO A;  4PNK A;  3TW1 A;  2LG1 A;  4TYZ A;  4KAX B;  2RLO A;  4L6E A;  1UNQ A;  5C16 A;  3PP2 A;  1ZVR A;  2YVC A;  3KSY A;  1BTN A;  3SO6 A;  3AU4 A;  1GC6 A;  2MKR A;  2KGX B;  4HAV B;  4B6H A;  4A6K A;  3P7Z A;  1NTV A;  1U5G A;  3F0W A;  5CLL B;  5DHA B;  4IOY X;  5HE3 A;  1Z87 A;  3NSU A;  1RRP B;  4HAU B;  1U29 A;  2D11 A;  4TKN A;  4HB4 B;  2DN6 A;  3F5R A;  3U8Z A;  3WYF B;  2DHK A;  2KUP A;  2CY4 A;  4HAW B;  1XCG A;  2P8V A;  1X1G A;  3LJU X;  1GG3 A;  4P7I A;  1K5G B;  2YT1 A;  5FI0 A;  4DX9 0;  2YS3 A;  2COA A;  1UPQ A;  4F7H A;  5HE0 A;  5FI1 A;  2J0K A;  5C5B B;  1OY2 A;  3BJI A;  5JHG A;  2GJY A;  1WI1 A;  3M1I B;  4F7U P;  2W2W A;  2DX5 A;  1EVH A;  2FJL A;  4CHM A;  1EF1 A;  5D3W A;  2D9X A;  2D9Z A;  3QWM A;  2YS5 A;  1WGU A;  4DXA B;  1E5W A;  2D9W A;  1FGZ A;  5D3X A;  2Q13 A;  3HW2 B;  1GC7 A;  2NZ8 B;  4BBK A;  1P6S A;  3SNH A;  3V5W A;  5C6R A;  1M7E A;  3D8E A;  4DBB A;  2W2X D;  5CLQ B;  3TO1 A;  1K5D B;  4A5K A;  1NTY A;  2D10 A;  2W2X C;  1ZSQ A;  2I1J A;  3VIA A;  1H10 A;  1V5M A;  2GS0 A;  3CIK A;  2GCJ A;  1MIZ B;  2K2J A;  2L2I A;  2COC A; 
#chains in the Genus database with same CATH topology
 2I1K A;  4NSW A;  3DXD A;  4ZRI A;  2KCJ A;  4MT7 A;  2MFQ A;  1PFJ A;  3B77 A;  4GXB A;  3AU5 A;  3NWA A;  5LG4 B;  1WG7 A;  4HAY B;  1XX0 A;  4H8S A;  3O96 A;  2EJ8 A;  3OAN A;  1X86 A;  2RGN B;  2YSZ A;  2DKQ A;  2BCJ A;  1DDM A;  1M7R A;  1ISN A;  1UEF A;  2LOZ A;  4CYE A;  4YON A;  2D2Q A;  2R2Y A;  5LOP B;  2DYQ A;  1PMS A;  3QIJ A;  1LW3 A;  4HHV A;  3U12 A;  1Y19 B;  1FHX A;  1KZG A;  4GZU A;  2G35 A;  5J3Q A;  2YS1 A;  2Z59 A;  3N7C A;  2K8E A;  4HB2 B;  2COF A;  3D8F A;  1PLS A;  2P0D A;  2RUK B;  2VRW B;  2ZPY A;  1V89 A;  2EMT A;  1X1F A;  2DLW A;  5I2S A;  1KI1 B;  1V5U A;  1ZYI A;  2UVM A;  3U7D A;  1MI1 A;  2I5F A;  4K2P A;  3WA0 A;  3KY9 A;  1WJM A;  5HE2 A;  1XD4 A;  2DA0 A;  3DXC A;  4ZRJ A;  1AQC A;  3GYO A;  1DRO A;  2L1C A;  3SYX A;  1FHO A;  1WGQ A;  2VKI A;  1WVH A;  2EMS A;  5DH9 B;  2X18 A;  4KVG B;  1B55 A;  3HSA A;  1V88 A;  4DIX A;  1P3R A;  3TCA A;  3PG7 A;  3RCP A;  1MPH A;  2RSG A;  4KHA A;  2K2U A;  2DX1 A;  2GCL A;  2CY5 A;  2PZ1 A;  3ODW A;  5GOW B;  2ELB A;  2P0F A;  4EJN A;  4HDQ A;  2Z13 A;  3NW8 A;  4D6W A;  2Y8G A;  3DXE A;  5M4Y B;  1OQN A;  4NY0 A;  3ZVR A;  1FAO A;  1EAZ A;  1FHW A;  1Q67 A;  2K00 A;  4GOU A;  4IFS A;  1J19 A;  4QJ5 B;  1DDW A;  1I2H A;  4OT1 A;  5DIF B;  4HDO A;  2ELA A;  2V76 A;  5HE1 A;  4HAX B;  1BWN A;  1V61 A;  1TXD A;  3X23 A;  2DKP A;  3KRW A;  1DDV A;  4F7G A;  2D4Q A;  4GMV A;  4QJ4 B;  2J59 M;  2CRF A;  2MDX A;  1MAI A;  2H7E A;  3UZT A;  3D8D A;  1DBH A;  5JLJ B;  5KQ4 A;  1RJ2 A;  1NU2 A;  2H7D A;  1FB8 A;  1FOE A;  4HB3 B;  2DYN A;  3A98 B;  4QXA B;  3KZ1 A;  4GMX B;  1NI2 A;  2UZR A;  4CHJ A;  2QKL A;  4KHO A;  2J0J A;  3T06 A;  3TFM A;  2OQB A;  1BAK A;  1U5E A;  3PEG A;  1WJ1 A;  3FSS A;  2D9Y A;  4Z2N A;  3PSC A;  3SUZ A;  4EMO A;  4WSF A;  5LON B;  4A6H A;  2GUM A;  4PQ0 A;  5J3Y A;  2Y7B A;  2UZS A;  4K17 A;  3SV1 A;  5C5B A;  4EKU A;  2VSZ A;  2DHJ A;  3FM8 C;  4A6F A;  2Y8F A;  5JHH A;  3HQC A;  2RRF A;  4KHB B;  1IRS A;  1TJ6 A;  1MK7 B;  4QJ3 B;  5DI9 B;  1MK9 B;  1UPR A;  4K81 A;  1Y5O A;  4WJ7 A;  2M38 A;  1TQZ A;  2M14 A;  3QBV B;  2Z0Q A;  4GPT B;  2NBV A;  2I5C A;  2D9V A;  2JP2 A;  2LOX A;  1W1G A;  2R0D A;  1SGH A;  4K2O A;  4MK0 A;  2HE7 A;  3MPX A;  1MKE A;  2ROV A;  1XR0 B;  2IFS A;  2N0Y A;  3G9W A;  2MWN B;  1H4R A;  5L81 A;  4HB0 B;  1XOD A;  3CXB B;  4HAZ B;  5KQ1 A;  3KRX A;  5I2M A;  3A8Q A;  3ULC A;  1X05 A;  4YL8 A;  2YT2 A;  2Z0P A;  4GNK B;  1U5F A;  2N23 A;  4WVF B;  1T77 A;  3TVV A;  3GYP A;  1SHC A;  5DHF B;  2J0M A;  2AEH A;  2RVB B;  3AJ4 A;  4DX8 A;  5D27 A;  1AWE A;  1W1D A;  1ZC4 B;  1U5D A;  3FEH A;  1ZM0 A;  2OTX A;  2YRY A;  3MDB C;  4C0A A;  5KCV A;  4IAP A;  2KIE A;  3HK0 A;  4A6F B;  1I7A A;  2YT0 A;  1DYN A;  1U2B A;  3PVW A;  2IYB A;  1UNP A;  2NMB A;  3DCX A;  3OHM B;  1ZC3 B;  3PZD A;  3BIN A;  4Z2M B;  1XKE A;  2CAY A;  2ADZ A;  2LKO A;  2YF0 A;  3ML4 A;  1V5P A;  2Z4D A;  2HTH B;  5J3T A;  3IVF A;  3PVL A;  4MY6 A;  5C79 A;  5JP4 A;  3PVU A;  1FGY A;  3ODX A;  4GN1 A;  2QKM A;  4ZRK A;  1EGX A;  1N3H A;  2RNR B;  3ZDT A;  1QC6 A;  1KZ7 A;  2LUL A;  4XWX A;  5EFX A;  2Z0O A;  2P0H A;  2E2X A;  2EC1 A;  3NWD A;  2FJU B;  2ROZ B;  2DHI A;  2XQN M;  1X11 A;  1BTK A;  3HIE A;  4OSN A;  1W1H A;  3A8P A;  4Y94 A;  3P6A A;  2KR0 A;  4HAT B;  1U27 A;  2DTC A;  5D3V A;  2DFK A;  2LYD A;  3ULB A;  1UNR A;  2R09 A;  2Z14 A;  5D3Y A;  4D0N B;  3VOQ A;  1OMW A;  2COD A;  1MIX A;  1LB1 A;  2AL6 A;  1QQG A;  2K49 A;  1J0W A;  1P5T A;  3ODO A;  4PNK A;  3NWF A;  3TW1 A;  2LG1 A;  4TYZ A;  4KAX B;  2RLO A;  4L6E A;  2KUQ A;  1UNQ A;  5C16 A;  3PP2 A;  1ZVR A;  2YVC A;  3KSY A;  1BTN A;  3SO6 A;  3AU4 A;  1GC6 A;  2MKR A;  2KGX B;  4HAV B;  4B6H A;  4HSI A;  4A6K A;  3P7Z A;  1NTV A;  1U5G A;  3F0W A;  5CLL B;  5DHA B;  4IOY X;  5HE3 A;  4CSQ A;  1Z87 A;  3NSU A;  1RRP B;  4HAU B;  1U29 A;  2D11 A;  4TKN A;  4HB4 B;  2DN6 A;  3F5R A;  3U8Z A;  3WYF B;  2DHK A;  2KUP A;  2CY4 A;  4HAW B;  1XCG A;  2P8V A;  1X1G A;  3LJU X;  1GG3 A;  4P7I A;  1K5G B;  2YT1 A;  5FI0 A;  4DX9 0;  2YS3 A;  2COA A;  1UPQ A;  4F7H A;  5HE0 A;  5FI1 A;  2J0K A;  5C5B B;  1OY2 A;  3BJI A;  5JHG A;  2GJY A;  1WI1 A;  3M1I B;  4F7U P;  2W2W A;  3A58 A;  2DX5 A;  4KHB A;  1EVH A;  2FJL A;  4CHM A;  1EF1 A;  5D3W A;  2D9X A;  2D9Z A;  3QWM A;  2YS5 A;  1WGU A;  4DXA B;  1E5W A;  2D9W A;  1FGZ A;  4L1R A;  5D3X A;  2Q13 A;  3HW2 B;  2KIG A;  1GC7 A;  2NZ8 B;  5IRS A;  2ZKM X;  4BBK A;  1P6S A;  3SNH A;  3V5W A;  5C6R A;  3D8E A;  1M7E A;  3FVC A;  4DBB A;  2W2X D;  5CLQ B;  3TO1 A;  1K5D B;  4A5K A;  1NTY A;  2D10 A;  2W2X C;  1ZSQ A;  2I1J A;  3VIA A;  1H10 A;  1V5M A;  2GS0 A;  3CIK A;  2GCJ A;  1MIZ B;  2K2J A;  2L2I A;  2COC A; 
#chains in the Genus database with same CATH homology
 2I1K A;  4NSW A;  3DXD A;  4ZRI A;  2KCJ A;  4MT7 A;  2MFQ A;  1PFJ A;  4GXB A;  3AU5 A;  1WG7 A;  4HAY B;  1XX0 A;  4H8S A;  3O96 A;  2EJ8 A;  3OAN A;  1X86 A;  2RGN B;  2YSZ A;  2DKQ A;  2BCJ A;  1DDM A;  1M7R A;  1ISN A;  1UEF A;  2LOZ A;  4CYE A;  4YON A;  2D2Q A;  5LOP B;  2DYQ A;  1PMS A;  3QIJ A;  1LW3 A;  4HHV A;  1Y19 B;  1FHX A;  1KZG A;  4GZU A;  2G35 A;  5J3Q A;  2YS1 A;  3N7C A;  4HB2 B;  2COF A;  3D8F A;  1PLS A;  2P0D A;  2RUK B;  2VRW B;  2ZPY A;  1V89 A;  2EMT A;  1X1F A;  2DLW A;  1KI1 B;  1V5U A;  3U7D A;  2UVM A;  2I5F A;  4K2P A;  3WA0 A;  3KY9 A;  1WJM A;  5HE2 A;  1XD4 A;  2DA0 A;  3DXC A;  4ZRJ A;  1AQC A;  3GYO A;  1DRO A;  2L1C A;  3SYX A;  1FHO A;  1WGQ A;  2VKI A;  1WVH A;  2EMS A;  5DH9 B;  2X18 A;  4KVG B;  1B55 A;  1V88 A;  1P3R A;  3TCA A;  3PG7 A;  3RCP A;  1MPH A;  2RSG A;  4KHA A;  2K2U A;  2DX1 A;  2GCL A;  2CY5 A;  2PZ1 A;  3ODW A;  5GOW B;  2ELB A;  2P0F A;  4EJN A;  4HDQ A;  2Y8G A;  3DXE A;  1OQN A;  4NY0 A;  3ZVR A;  1FAO A;  1EAZ A;  1FHW A;  1Q67 A;  2K00 A;  4IFS A;  1J19 A;  1DDW A;  1I2H A;  5DIF B;  5HE1 A;  4HDO A;  2ELA A;  2V76 A;  4HAX B;  1BWN A;  1V61 A;  1TXD A;  3X23 A;  2DKP A;  3KRW A;  1DDV A;  4F7G A;  2D4Q A;  4GMV A;  2J59 M;  2CRF A;  2MDX A;  1MAI A;  2H7E A;  3UZT A;  3D8D A;  1DBH A;  5JLJ B;  5KQ4 A;  1RJ2 A;  1NU2 A;  2H7D A;  1FB8 A;  1FOE A;  4HB3 B;  2DYN A;  3A98 B;  3KZ1 A;  4GMX B;  1NI2 A;  2UZR A;  4CHJ A;  2QKL A;  4KHO A;  2J0J A;  3T06 A;  3TFM A;  2OQB A;  1BAK A;  1U5E A;  3PEG A;  1WJ1 A;  3FSS A;  2D9Y A;  4Z2N A;  3PSC A;  3SUZ A;  4EMO A;  4WSF A;  5LON B;  4A6H A;  4PQ0 A;  5J3Y A;  2Y7B A;  2UZS A;  4K17 A;  3SV1 A;  5C5B A;  4EKU A;  2VSZ A;  2DHJ A;  3FM8 C;  4A6F A;  2Y8F A;  5JHH A;  3HQC A;  4KHB B;  1IRS A;  1TJ6 A;  1MK7 B;  5DI9 B;  1MK9 B;  1UPR A;  4K81 A;  1Y5O A;  4WJ7 A;  2M38 A;  1TQZ A;  2M14 A;  3QBV B;  2Z0Q A;  4GPT B;  2I5C A;  2D9V A;  2JP2 A;  2LOX A;  1W1G A;  2R0D A;  1SGH A;  4K2O A;  4MK0 A;  2HE7 A;  3MPX A;  1MKE A;  2ROV A;  1XR0 B;  2IFS A;  2N0Y A;  3G9W A;  2MWN B;  1H4R A;  5L81 A;  4HB0 B;  1XOD A;  3CXB B;  4HAZ B;  5KQ1 A;  3KRX A;  3A8Q A;  3ULC A;  1X05 A;  4YL8 A;  2Z0P A;  1U5F A;  2N23 A;  4WVF B;  3TVV A;  3GYP A;  1SHC A;  5DHF B;  2J0M A;  2AEH A;  2RVB B;  3AJ4 A;  4DX8 A;  5D27 A;  1AWE A;  1W1D A;  1ZC4 B;  1U5D A;  3FEH A;  1ZM0 A;  2OTX A;  2YRY A;  3MDB C;  4C0A A;  5KCV A;  4IAP A;  3HK0 A;  4A6F B;  1I7A A;  2YT0 A;  1DYN A;  1U2B A;  3PVW A;  2IYB A;  1UNP A;  2NMB A;  1ZC3 B;  3PZD A;  3BIN A;  4Z2M B;  1XKE A;  2CAY A;  2ADZ A;  2LKO A;  2YF0 A;  3ML4 A;  1V5P A;  2HTH B;  5J3T A;  3IVF A;  3PVL A;  4MY6 A;  5C79 A;  5JP4 A;  3PVU A;  1FGY A;  3ODX A;  4GN1 A;  2QKM A;  4ZRK A;  1EGX A;  1N3H A;  2RNR B;  3ZDT A;  1QC6 A;  1KZ7 A;  2LUL A;  4XWX A;  5EFX A;  2Z0O A;  2P0H A;  2E2X A;  2EC1 A;  2ROZ B;  2DHI A;  2XQN M;  1X11 A;  1BTK A;  1W1H A;  3A8P A;  4Y94 A;  3P6A A;  4HAT B;  1U27 A;  2DTC A;  5D3V A;  2DFK A;  2LYD A;  3ULB A;  1UNR A;  2R09 A;  5D3Y A;  4D0N B;  3VOQ A;  1OMW A;  2COD A;  1MIX A;  1LB1 A;  2AL6 A;  1QQG A;  1J0W A;  1P5T A;  3ODO A;  4PNK A;  3TW1 A;  2LG1 A;  4TYZ A;  4KAX B;  2RLO A;  4L6E A;  1UNQ A;  5C16 A;  3PP2 A;  1ZVR A;  2YVC A;  3KSY A;  1BTN A;  3SO6 A;  3AU4 A;  1GC6 A;  2MKR A;  2KGX B;  4HAV B;  4B6H A;  4A6K A;  3P7Z A;  1NTV A;  1U5G A;  3F0W A;  5CLL B;  5DHA B;  4IOY X;  5HE3 A;  1Z87 A;  3NSU A;  1RRP B;  4HAU B;  1U29 A;  2D11 A;  4TKN A;  4HB4 B;  2DN6 A;  3F5R A;  3U8Z A;  3WYF B;  2DHK A;  2KUP A;  2CY4 A;  4HAW B;  1XCG A;  2P8V A;  1X1G A;  3LJU X;  1GG3 A;  4P7I A;  1K5G B;  2YT1 A;  5FI0 A;  4DX9 0;  2YS3 A;  2COA A;  1UPQ A;  4F7H A;  5HE0 A;  5FI1 A;  2J0K A;  5C5B B;  1OY2 A;  3BJI A;  5JHG A;  2GJY A;  1WI1 A;  3M1I B;  4F7U P;  2W2W A;  2DX5 A;  1EVH A;  2FJL A;  4CHM A;  1EF1 A;  5D3W A;  2D9X A;  2D9Z A;  3QWM A;  2YS5 A;  1WGU A;  4DXA B;  1E5W A;  2D9W A;  1FGZ A;  5D3X A;  2Q13 A;  3HW2 B;  1GC7 A;  2NZ8 B;  4BBK A;  1P6S A;  3SNH A;  3V5W A;  5C6R A;  1M7E A;  3D8E A;  4DBB A;  2W2X D;  5CLQ B;  3TO1 A;  1K5D B;  4A5K A;  1NTY A;  2D10 A;  2W2X C;  1ZSQ A;  2I1J A;  3VIA A;  1H10 A;  1V5M A;  2GS0 A;  3CIK A;  2GCJ A;  1MIZ B;  2K2J A;  2L2I A;  2COC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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