4I7CA

Siah1 mutant bound to synthetic peptide (ace)klrpv(23p)mvrpwvr
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
192
structure length
188
Chain Sequence
ANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSICTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-based design of covalent siah inhibitors.
pubmed doi rcsb
molecule tags Ligase/ligase inhibitor
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase SIAH1
total genus 45
structure length 188
sequence length 192
chains with identical sequence C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2012-11-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 4i7cA02
3.30.40.10 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Zinc/RING finger domain, C3HC4 (zinc finger) 4i7cA01
5KH9A 3IVVA 5LCWB 1FP0A 5B78A 1Z2QA 3ZTGA 3ZYQA 2LDRA 2CSZA 2YQMA 3HQLA 4L58A 2MA5A 1X4UA 2YSMA 2ZETC 4LADB 3PUQA 4CA1A 1N87A 2MNZA 3EB5A 4O64A 2G6QA 2H0DB 2YHOA 2F6JA 3LRQA 3C5KA 2F1WA 1LB4A 2VPGA 3KNVA 3IVBA 5TDWA 5FB1A 2FUIA 1U6GB 3NG2A 4IC3A 3C6WA 1DVPA 5H1UA 2ECWA 1FBVA 2KU3A 5B77A 4XI1A 2C2VS 1XWHA 2RI7A 3O7AA 3M62A 4MVTA 2KWOA 3KQIA 3LQJA 3U5MA 2VJEB 5H1TA 5LKZA 2JRJA 1D00A 3O34A 2A25A 1WFKA 3PHDA 1CHCA 1VD4A 3SOUA 2KWKA 3L11A 2CSYA 4PTBA 2KGGA 2YREA 3L1ZB 1YY6A 4B7YC 4R8PK 2RSDA 3HCSA 4GNFA 2XB1A 2K17A 2VNFA 2MNYA 1CA9A 3MQRA 4A4BA 2CKLA 5KH3A 1Z6UA 3I2DA 5J3XA 1WEQA 3V43A 2F1XA 2K1JA 4AVXA 2LXHC 2F1YA 1LB5A 3T6RA 4Q6FA 5FERA 4WZ0A 2YSJA 3U5NA 2L5UA 3O35A 5TABA 4FK5A 2CR2A 4ZQLA 5LKXA 4JJQA 2E6RA 5KH7A 2MD8C 5G0FA 1ZMSA 4AUQB 3ZVYA 2AN6A 1L0AA 3IVQA 2L0BA 2LGGA 2YT5A 3HQHA 3LQIA 2LRIC 3VK6A 2YQLA 1WEOA 5C11A 3GL6A 5TRBA 4KG9A 1FLKA 2VPBA 1WIMA 3GV4A 3MHSA 2XXNA 5D1LB 2K4DA 2HDPA 1HYJA 3U5PA 2M85A 4P5OB 4I7CA 4N3WA 1BORA 4MSXA 2YUCA 1V87A 5LKTA 2Y1MA 1CA4A 4NN2A 4IC2A 1CZYA 2K16A 4GNEA 1WEUA 5JG6A 4LLBA 2Y1NA 2KWNA 5D1KB 3U5OA 2JMIA 2KREA 4YBMA 2M3HA 5G04B 1QSCA 1K2FA 2OXQC 2VJFB 4K8UA 3M99A 2YU4A 2VPDA 3DPLR 4S3OC 3N9NA 4LJNA 1VFYA 4YBTA 1LB6A 2I50A 5G05B 2L80A 2VP7A 5TBNA 4ZDTA 2KR4A 4YBSA 4LK9A 1F62A 4YSIA 2LXPC 2EA6A 1ZBDB 3O33A 5AIUA 5I3LA 2LGKA 1WEVA 2LV9A 4O1VA 2PUYA 4GNDA 1G25A 4GB0A 2FOPA 4QF2A 1IYMA 5DINA 3HU6A 1CZZA 2VPEA 2ECVA 3EB6A 4QF3A 4R2YA 2PNXA 3M63A 4PPEA 4AYCB 1T1HA 2JMJA 2HYED 4BBQA 3ZJBA 3N9PA 4GWMA 2MUMA 4FIPA 2FOJA 4FO9A 2XEUA 2H0DA 1WEWA 4UI9B 3HCTA 5B8DA 5B75A 4BHWA 1X4JA 2NAAA 1WENA 4N4FA 2Y43A 3ASLA 2CT2A 3N9LA 4W4UA 2YYRA 3FL2A 4UP5A 2UZGA 5LKUA 1D0JA 3HSVA 4V3KC 2F6NA 2FUUA 3HCUA 1Z60A 3RPGC 5FB0A 3ZNIA 5B76A 2G45A 1FLLA 4LKAA 4WZ3B 1F3VB 2YURA 3RPGB 2ECGA 3O70A 2EGPA 4V3LC 4L7XA 2KWJA 2G43A 4WA6A 2M6MA 2M1RA 5B79A 1RF3A 3N9OA 5H1VA 2F1ZA 3SOXA 1D0AA 4TKPB 1KZZA 4GNGA 2FSAA 3SHBA 3KV6A 2MD7B 2MIQA 2YW8A 5TDRA 4A4CA 2QJ0A 4I7DA 1WEMA 2YHNA 2LGLA 4FJCA 4F52B 5AITA 4A49A 2ECNA 1WE9A 2FOOA 4YADA 4ZUXU 5H9MA 2QIZA 2ECJA 4Z8MA 2EODA 3MQSC 2DX8A 4YAXA 1D01A 1X4IA 2CKLB 4GJHA 3O36A 4S3OB 4X3GA 4M4EA 3L1XA 4B86C 4WZ2A 1WILA 2L75A 4A0CD 1JM7A 3DQVR 2C2LA 3N9QA 5DKAA 3ZVZB 5C13A 2BAYA 2MA6A 2MT5A 3T7LA 1RMDA 3IHPA 1E4UA 3LQHA 5EYAF 1JOCA 3HQMA 4UP0A 5D1MB 4GWNA 3RTRB 1MM2A 3PURA 2LQ6A 1LDJB 3ZPVE 2ECIA 3HQIA 3ZPV1 2VJFA 4YC9A 1HYIA 1YZEA 2L43A 3HTKC 1WEEA 2KIZA 4GHUA 1MM3A 5E1TA 1WESA 2KFTA 2GKWA 3O37A 1LDKC 2IDAA 2KYUA 3QZVA 4YABA 2ECTA 2KE1A 2VJEA 2D8SA 1WEPA 4CCGX 3MHHA 5FEYA 3N9MA 3KV5A 2JMDA 3SOWA 4AP4A 4AYCA 4C9ZA 4R7EA 2KGIA 2F42A 2QICA 2E6SA 2LN0A 4YATA 1VYXA 4I7BA 1WGMA 1JM7B 2LGVA
chains in the Genus database with same CATH superfamily
5KH9A 3IVVA 5LCWB 1FP0A 5B78A 1Z2QA 3ZTGA 3ZYQA 2LDRA 2CSZA 2YQMA 3HQLA 5SVYA 4L58A 2MA5A 2XOYA 2KKYA 3T9KA 1X4UA 2YSMA 2ZETC 4LADB 3PUQA 4CA1A 2IQJA 1N87A 2MNZA 3EB5A 3SUBA 4O64A 2G6QA 2H0DB 2YHOA 2F6JA 3LRQA 3C5KA 2XP0A 2F1WA 1LB4A 2VPGA 3KNVA 2L7PA 3IVBA 5TDWA 5FB1A 2FUIA 1U6GB 2FD4A 3NG2A 4IC3A 3C6WA 1DVPA 5H1UA 2ECWA 1FBVA 2KU3A 5B77A 4XI1A 2C2VS 1XWHA 2RI7A 3O7AA 3M62A 4MVTA 2KWOA 3KQIA 3LQJA 3U5MA 2VJEB 5H1TA 5LKZA 2JRJA 1D00A 3O34A 2A25A 1WFKA 3PHDA 1CHCA 1VD4A 3SOUA 2KWKA 3L11A 2CSYA 4PTBA 2KGGA 2YREA 3L1ZB 1YY6A 4B7YC 4R8PK 2RSDA 3HCSA 4GNFA 2XB1A 2K17A 2VNFA 2MNYA 1CA9A 3MQRA 4A4BA 2CKLA 5KH3A 1Z6UA 3I2DA 5J3XA 1WEQA 3H7HA 3V43A 2F1XA 2K1JA 4AVXA 2LXHC 2F1YA 1LB5A 3DWDA 3T6RA 4Q6FA 5FERA 4WZ0A 2YSJA 3LJUX 3U5NA 2L5UA 3O35A 5TABA 4FK5A 2CR2A 2DSMA 4ZQLA 5LKXA 4JJQA 2E6RA 3FJUB 5KH7A 2MD8C 2CSVA 5G0FA 1ZMSA 4AUQB 2CRRA 4OGCA 4O62A 3ZVYA 2AN6A 1L0AA 3O47A 3IVQA 2L0BA 2LGGA 2YT5A 3HQHA 3LQIA 2LRIC 3VK6A 2YQLA 1WEOA 5C11A 3GL6A 5TRBA 4KG9A 1FLKA 2VPBA 1WIMA 3GV4A 3MHSA 2MKEA 2E61A 2XXNA 5D1LB 2K4DA 2HDPA 1HYJA 3U5PA 2M85A 4P5OB 5SVXA 4I7CA 4N3WA 1BORA 2XOCA 4MSXA 2YUCA 1V87A 5LKTA 5K3QA 2Y1MA 1CA4A 4NN2A 4IC2A 1CZYA 2K16A 4GNEA 1WEUA 5JG6A 4LLBA 2Y1NA 2JM3A 2KWNA 5D1KB 3U5OA 2JMIA 2KREA 4YBMA 2M3HA 5G04B 1QSCA 1K2FA 2OXQC 2VJFB 4K8UA 3M99A 2M13A 3DPLR 2VPDA 2YU4A 5SVIB 4S3OC 3N9NA 4LJNA 1VFYA 4YBTA 1LB6A 2I50A 5G05B 2L80A 2VP7A 3PLWA 5TBNA 4ZDTA 4Z0OA 2KR4A 4YBSA 4LK9A 1F62A 3DDTA 4YSIA 2LXPC 2EA6A 1ZBDB 3O33A 3LDYA 5AIUA 5I3LA 2LGKA 1WEVA 2LV9A 4O1VA 2YVRA 2PUYA 4GNDA 1G25A 4GB0A 2FOPA 4QF2A 1IYMA 2KKXA 5DINA 3HU6A 1CZZA 2VPEA 2ECVA 3EB6A 4QF3A 4R2YA 2PNXA 3M63A 4PPEA 4AYCB 1T1HA 2JMJA 2HYED 4BBQA 3ZJBA 3E2DA 3N9PA 4GWMA 2MUMA 4FIPA 2FOJA 4FO9A 2XEUA 3KDEC 2H0DA 1WEWA 4UI9B 3HCTA 5B8DA 2D8UA 5B75A 4BHWA 1X4JA 2NAAA 1WENA 4N4FA 2Y43A 3ASLA 2CT2A 3N9LA 4W4UA 2FFWA 2YYRA 3FL2A 4UP5A 2UZGA 5LKUA 1D0JA 2EXUA 3HSVA 4V3KC 2F6NA 2FUUA 3HCUA 1Z60A 3RPGC 5FB0A 3ZNIA 5B76A 2G45A 1FLLA 4LKAA 4WZ3B 1F3VB 2YURA 3RPGB 2LAUA 2ECGA 3O70A 2EGPA 4V3LC 4L7XA 2KWJA 2G43A 4WA6A 2M6MA 1DCQA 2M1RA 5B79A 1RF3A 3N9OA 5H1VA 2F1ZA 3SOXA 1D0AA 4TKPB 1KZZA 4GNGA 2FSAA 3SHBA 3KV6A 2MD7B 2MIQA 2YW8A 5TDRA 4A4CA 2QJ0A 4I7DA 1WEMA 2YHNA 2LGLA 4FJCA 4F52B 5AITA 4A49A 2ECNA 1WE9A 2CONA 2FOOA 4YADA 4ZUXU 5H9MA 2QIZA 2DJAA 3M7KA 2ECJA 4Z8MA 2EODA 3MQSC 2DX8A 4YAXA 4H9DA 1D01A 1X4IA 3JUEA 3Q1DA 2CKLB 4GJHA 3O36A 2XOZA 4S3OB 4X3GA 4M4EA 3L1XA 4B86C 4WZ2A 1WILA 2L75A 4A0CD 1JM7A 3DQVR 2C2LA 3FM8C 3N9QA 5DKAA 3ZVZB 5C13A 2BAYA 2MA6A 2MT5A 3T7LA 1RMDA 3IHPA 3LVRE 1E4UA 3LQHA 2B0OE 5EYAF 1JOCA 3FEHA 3HQMA 4UP0A 5D1MB 4GWNA 3RTRB 2OWAA 1MM2A 3PURA 2LQ6A 1LDJB 4Z0RA 2EGMA 3ZPVE 2ECIA 4OGEA 3HQIA 3ZPV1 2VJFA 3FANA 4YC9A 1HYIA 5SVIA 1YZEA 2L43A 3HTKC 1WEEA 2RR4A 2KIZA 4GHUA 3MDBC 1MM3A 5E1TA 3FAOA 2JUNA 1WESA 2KFTA 2GKWA 3O37A 1LDKC 2IDAA 2KYUA 3QZVA 2CRWA 4YABA 2ECTA 2KE1A 2VJEA 2D8SA 1WEPA 4CCGX 3MHHA 5FEYA 2P57A 3N9MA 3KV5A 2JMDA 3SOWA 4F1PA 4AP4A 4AYCA 4C9ZA 4R7EA 2KGIA 2F42A 2QICA 2E6SA 2LN0A 4YATA 4QQ4A 1VYXA 4I7BA 3LVQE 1MBMA 1WGMA 1JM7B 2LGVA
chains in the Genus database with same CATH topology
5KH9A 3IVVA 5LCWB 1FP0A 5B78A 1Z2QA 3ZTGA 3ZYQA 2LDRA 2CSZA 2YQMA 3HQLA 4L58A 2MA5A 1X4UA 2YSMA 2ZETC 4LADB 3PUQA 4CA1A 1N87A 2MNZA 3EB5A 4O64A 2G6QA 2H0DB 2YHOA 2F6JA 3LRQA 3C5KA 2F1WA 1LB4A 2VPGA 3KNVA 3IVBA 5TDWA 5FB1A 2FUIA 1U6GB 3NG2A 4IC3A 3C6WA 1DVPA 5H1UA 2ECWA 1FBVA 2KU3A 5B77A 4XI1A 2C2VS 1XWHA 2RI7A 3O7AA 3M62A 4MVTA 2KWOA 3KQIA 3LQJA 3U5MA 2VJEB 5H1TA 5LKZA 2JRJA 1D00A 3O34A 2A25A 1WFKA 3PHDA 1CHCA 1VD4A 3SOUA 2KWKA 3L11A 2CSYA 4PTBA 2KGGA 2YREA 3L1ZB 1YY6A 4B7YC 4R8PK 2RSDA 3HCSA 4GNFA 2XB1A 2K17A 2VNFA 2MNYA 1CA9A 3MQRA 4A4BA 2CKLA 5KH3A 1Z6UA 3I2DA 5J3XA 1WEQA 3V43A 2F1XA 2K1JA 4AVXA 2LXHC 2F1YA 1LB5A 3T6RA 4Q6FA 5FERA 4WZ0A 2YSJA 3U5NA 2L5UA 3O35A 5TABA 4FK5A 2CR2A 4ZQLA 5LKXA 4JJQA 2E6RA 5KH7A 2MD8C 5G0FA 1ZMSA 4AUQB 3ZVYA 2AN6A 1L0AA 3IVQA 2L0BA 2LGGA 2YT5A 3HQHA 3LQIA 2LRIC 3VK6A 2YQLA 1WEOA 5C11A 3GL6A 5TRBA 4KG9A 1FLKA 2VPBA 1WIMA 3GV4A 3MHSA 2XXNA 5D1LB 2K4DA 2HDPA 1HYJA 3U5PA 2M85A 4P5OB 4I7CA 4N3WA 1BORA 4MSXA 2YUCA 1V87A 5LKTA 2Y1MA 1CA4A 4NN2A 4IC2A 1CZYA 2K16A 4GNEA 1WEUA 5JG6A 4LLBA 2Y1NA 2KWNA 5D1KB 3U5OA 2JMIA 2KREA 4YBMA 2M3HA 5G04B 1QSCA 1K2FA 2OXQC 2VJFB 4K8UA 3M99A 2YU4A 2VPDA 3DPLR 4S3OC 3N9NA 4LJNA 1VFYA 4YBTA 1LB6A 2I50A 5G05B 2L80A 2VP7A 5TBNA 4ZDTA 2KR4A 4YBSA 4LK9A 1F62A 4YSIA 2LXPC 2EA6A 1ZBDB 3O33A 5AIUA 5I3LA 2LGKA 1WEVA 2LV9A 4O1VA 2PUYA 4GNDA 1G25A 4GB0A 2FOPA 4QF2A 1IYMA 5DINA 3HU6A 1CZZA 2VPEA 2ECVA 3EB6A 4QF3A 4R2YA 2PNXA 3M63A 4PPEA 4AYCB 1T1HA 2JMJA 2HYED 4BBQA 3ZJBA 3N9PA 4GWMA 2MUMA 4FIPA 2FOJA 4FO9A 2XEUA 2H0DA 1WEWA 4UI9B 3HCTA 5B8DA 5B75A 4BHWA 1X4JA 2NAAA 1WENA 4N4FA 2Y43A 3ASLA 2CT2A 3N9LA 4W4UA 2YYRA 3FL2A 4UP5A 2UZGA 5LKUA 1D0JA 3HSVA 4V3KC 2F6NA 2FUUA 3HCUA 1Z60A 3RPGC 5FB0A 3ZNIA 5B76A 2G45A 1FLLA 4LKAA 4WZ3B 1F3VB 2YURA 3RPGB 2ECGA 3O70A 2EGPA 4V3LC 4L7XA 2KWJA 2G43A 4WA6A 2M6MA 2M1RA 5B79A 1RF3A 3N9OA 5H1VA 2F1ZA 3SOXA 1D0AA 4TKPB 1KZZA 4GNGA 2FSAA 3SHBA 3KV6A 2MD7B 2MIQA 2YW8A 5TDRA 4A4CA 2QJ0A 4I7DA 1WEMA 2YHNA 2LGLA 4FJCA 4F52B 5AITA 4A49A 2ECNA 1WE9A 2FOOA 4YADA 4ZUXU 5H9MA 2QIZA 2ECJA 4Z8MA 2EODA 3MQSC 2DX8A 4YAXA 1D01A 1X4IA 2CKLB 4GJHA 3O36A 4S3OB 4X3GA 4M4EA 3L1XA 4B86C 4WZ2A 1WILA 2L75A 4A0CD 1JM7A 3DQVR 2C2LA 3N9QA 5DKAA 3ZVZB 5C13A 2BAYA 2MA6A 2MT5A 3T7LA 1RMDA 3IHPA 1E4UA 3LQHA 5EYAF 1JOCA 3HQMA 4UP0A 5D1MB 4GWNA 3RTRB 1MM2A 3PURA 2LQ6A 1LDJB 3ZPVE 2ECIA 3HQIA 3ZPV1 2VJFA 4YC9A 1HYIA 1YZEA 2L43A 3HTKC 1WEEA 2KIZA 4GHUA 1MM3A 5E1TA 1WESA 2KFTA 2GKWA 3O37A 1LDKC 2IDAA 2KYUA 3QZVA 4YABA 2ECTA 2KE1A 2VJEA 2D8SA 1WEPA 4CCGX 3MHHA 5FEYA 3N9MA 3KV5A 2JMDA 3SOWA 4AP4A 4AYCA 4C9ZA 4R7EA 2KGIA 2F42A 2QICA 2E6SA 2LN0A 4YATA 1VYXA 4I7BA 1WGMA 1JM7B 2LGVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5KH9 A;  3IVV A;  5LCW B;  1FP0 A;  5B78 A;  1Z2Q A;  3ZTG A;  3ZYQ A;  2LDR A;  2CSZ A;  2YQM A;  3HQL A;  4L58 A;  2MA5 A;  1X4U A;  2YSM A;  2ZET C;  4LAD B;  3PUQ A;  4CA1 A;  1N87 A;  2MNZ A;  3EB5 A;  4O64 A;  2G6Q A;  2H0D B;  2YHO A;  2F6J A;  3LRQ A;  3C5K A;  2F1W A;  1LB4 A;  2VPG A;  3KNV A;  3IVB A;  5TDW A;  5FB1 A;  2FUI A;  1U6G B;  3NG2 A;  4IC3 A;  3C6W A;  1DVP A;  5H1U A;  2ECW A;  1FBV A;  2KU3 A;  5B77 A;  4XI1 A;  2C2V S;  1XWH A;  2RI7 A;  3O7A A;  3M62 A;  4MVT A;  2KWO A;  3KQI A;  3LQJ A;  3U5M A;  2VJE B;  5H1T A;  5LKZ A;  2JRJ A;  1D00 A;  3O34 A;  2A25 A;  1WFK A;  3PHD A;  1CHC A;  1VD4 A;  3SOU A;  2KWK A;  3L11 A;  2CSY A;  4PTB A;  2KGG A;  2YRE A;  3L1Z B;  1YY6 A;  4B7Y C;  4R8P K;  2RSD A;  3HCS A;  4GNF A;  2XB1 A;  2K17 A;  2VNF A;  2MNY A;  1CA9 A;  3MQR A;  4A4B A;  2CKL A;  5KH3 A;  1Z6U A;  3I2D A;  5J3X A;  1WEQ A;  3V43 A;  2F1X A;  2K1J A;  4AVX A;  2LXH C;  2F1Y A;  1LB5 A;  3T6R A;  4Q6F A;  5FER A;  4WZ0 A;  2YSJ A;  3U5N A;  2L5U A;  3O35 A;  5TAB A;  4FK5 A;  2CR2 A;  4ZQL A;  5LKX A;  4JJQ A;  2E6R A;  5KH7 A;  2MD8 C;  5G0F A;  1ZMS A;  4AUQ B;  3ZVY A;  2AN6 A;  1L0A A;  3IVQ A;  2L0B A;  2LGG A;  2YT5 A;  3HQH A;  3LQI A;  2LRI C;  3VK6 A;  2YQL A;  1WEO A;  5C11 A;  3GL6 A;  5TRB A;  4KG9 A;  1FLK A;  2VPB A;  1WIM A;  3GV4 A;  3MHS A;  2XXN A;  5D1L B;  2K4D A;  2HDP A;  1HYJ A;  3U5P A;  2M85 A;  4P5O B;  4I7C A;  4N3W A;  1BOR A;  4MSX A;  2YUC A;  1V87 A;  5LKT A;  2Y1M A;  1CA4 A;  4NN2 A;  4IC2 A;  1CZY A;  2K16 A;  4GNE A;  1WEU A;  5JG6 A;  4LLB A;  2Y1N A;  2KWN A;  5D1K B;  3U5O A;  2JMI A;  2KRE A;  4YBM A;  2M3H A;  5G04 B;  1QSC A;  1K2F A;  2OXQ C;  2VJF B;  4K8U A;  3M99 A;  2YU4 A;  2VPD A;  3DPL R;  4S3O C;  3N9N A;  4LJN A;  1VFY A;  4YBT A;  1LB6 A;  2I50 A;  5G05 B;  2L80 A;  2VP7 A;  5TBN A;  4ZDT A;  2KR4 A;  4YBS A;  4LK9 A;  1F62 A;  4YSI A;  2LXP C;  2EA6 A;  1ZBD B;  3O33 A;  5AIU A;  5I3L A;  2LGK A;  1WEV A;  2LV9 A;  4O1V A;  2PUY A;  4GND A;  1G25 A;  4GB0 A;  2FOP A;  4QF2 A;  1IYM A;  5DIN A;  3HU6 A;  1CZZ A;  2VPE A;  2ECV A;  3EB6 A;  4QF3 A;  4R2Y A;  2PNX A;  3M63 A;  4PPE A;  4AYC B;  1T1H A;  2JMJ A;  2HYE D;  4BBQ A;  3ZJB A;  3N9P A;  4GWM A;  2MUM A;  4FIP A;  2FOJ A;  4FO9 A;  2XEU A;  2H0D A;  1WEW A;  4UI9 B;  3HCT A;  5B8D A;  5B75 A;  4BHW A;  1X4J A;  2NAA A;  1WEN A;  4N4F A;  2Y43 A;  3ASL A;  2CT2 A;  3N9L A;  4W4U A;  2YYR A;  3FL2 A;  4UP5 A;  2UZG A;  5LKU A;  1D0J A;  3HSV A;  4V3K C;  2F6N A;  2FUU A;  3HCU A;  1Z60 A;  3RPG C;  5FB0 A;  3ZNI A;  5B76 A;  2G45 A;  1FLL A;  4LKA A;  4WZ3 B;  1F3V B;  2YUR A;  3RPG B;  2ECG A;  3O70 A;  2EGP A;  4V3L C;  4L7X A;  2KWJ A;  2G43 A;  4WA6 A;  2M6M A;  2M1R A;  5B79 A;  1RF3 A;  3N9O A;  5H1V A;  2F1Z A;  3SOX A;  1D0A A;  4TKP B;  1KZZ A;  4GNG A;  2FSA A;  3SHB A;  3KV6 A;  2MD7 B;  2MIQ A;  2YW8 A;  5TDR A;  4A4C A;  2QJ0 A;  4I7D A;  1WEM A;  2YHN A;  2LGL A;  4FJC A;  4F52 B;  5AIT A;  4A49 A;  2ECN A;  1WE9 A;  2FOO A;  4YAD A;  4ZUX U;  5H9M A;  2QIZ A;  2ECJ A;  4Z8M A;  2EOD A;  3MQS C;  2DX8 A;  4YAX A;  1D01 A;  1X4I A;  2CKL B;  4GJH A;  3O36 A;  4S3O B;  4X3G A;  4M4E A;  3L1X A;  4B86 C;  4WZ2 A;  1WIL A;  2L75 A;  4A0C D;  1JM7 A;  3DQV R;  2C2L A;  3N9Q A;  5DKA A;  3ZVZ B;  5C13 A;  2BAY A;  2MA6 A;  2MT5 A;  3T7L A;  1RMD A;  3IHP A;  1E4U A;  3LQH A;  5EYA F;  1JOC A;  3HQM A;  4UP0 A;  5D1M B;  4GWN A;  3RTR B;  1MM2 A;  3PUR A;  2LQ6 A;  1LDJ B;  3ZPV E;  2ECI A;  3HQI A;  3ZPV 1;  2VJF A;  4YC9 A;  1HYI A;  1YZE A;  2L43 A;  3HTK C;  1WEE A;  2KIZ A;  4GHU A;  1MM3 A;  5E1T A;  1WES A;  2KFT A;  2GKW A;  3O37 A;  1LDK C;  2IDA A;  2KYU A;  3QZV A;  4YAB A;  2ECT A;  2KE1 A;  2VJE A;  2D8S A;  1WEP A;  4CCG X;  3MHH A;  5FEY A;  3N9M A;  3KV5 A;  2JMD A;  3SOW A;  4AP4 A;  4AYC A;  4C9Z A;  4R7E A;  2KGI A;  2F42 A;  2QIC A;  2E6S A;  2LN0 A;  4YAT A;  1VYX A;  4I7B A;  1WGM A;  1JM7 B;  2LGV A; 
#chains in the Genus database with same CATH topology
 5KH9 A;  3IVV A;  5LCW B;  1FP0 A;  5B78 A;  1Z2Q A;  3ZTG A;  3ZYQ A;  2LDR A;  2CSZ A;  2YQM A;  3HQL A;  5SVY A;  4L58 A;  2MA5 A;  2XOY A;  2KKY A;  3T9K A;  1X4U A;  2YSM A;  2ZET C;  4LAD B;  3PUQ A;  4CA1 A;  2IQJ A;  1N87 A;  2MNZ A;  3EB5 A;  3SUB A;  4O64 A;  2G6Q A;  2H0D B;  2YHO A;  2F6J A;  3LRQ A;  3C5K A;  2XP0 A;  2F1W A;  1LB4 A;  2VPG A;  3KNV A;  2L7P A;  3IVB A;  5TDW A;  5FB1 A;  2FUI A;  1U6G B;  2FD4 A;  3NG2 A;  4IC3 A;  3C6W A;  1DVP A;  5H1U A;  2ECW A;  1FBV A;  2KU3 A;  5B77 A;  4XI1 A;  2C2V S;  1XWH A;  2RI7 A;  3O7A A;  3M62 A;  4MVT A;  2KWO A;  3KQI A;  3LQJ A;  3U5M A;  2VJE B;  5H1T A;  5LKZ A;  2JRJ A;  1D00 A;  3O34 A;  2A25 A;  1WFK A;  3PHD A;  1CHC A;  1VD4 A;  3SOU A;  2KWK A;  3L11 A;  2CSY A;  4PTB A;  2KGG A;  2YRE A;  3L1Z B;  1YY6 A;  4B7Y C;  4R8P K;  2RSD A;  3HCS A;  4GNF A;  2XB1 A;  2K17 A;  2VNF A;  2MNY A;  1CA9 A;  3MQR A;  4A4B A;  2CKL A;  5KH3 A;  1Z6U A;  3I2D A;  5J3X A;  1WEQ A;  3H7H A;  3V43 A;  2F1X A;  2K1J A;  4AVX A;  2LXH C;  2F1Y A;  1LB5 A;  3DWD A;  3T6R A;  4Q6F A;  5FER A;  4WZ0 A;  2YSJ A;  3LJU X;  3U5N A;  2L5U A;  3O35 A;  5TAB A;  4FK5 A;  2CR2 A;  2DSM A;  4ZQL A;  5LKX A;  4JJQ A;  2E6R A;  3FJU B;  5KH7 A;  2MD8 C;  2CSV A;  5G0F A;  1ZMS A;  4AUQ B;  2CRR A;  4OGC A;  4O62 A;  3ZVY A;  2AN6 A;  1L0A A;  3O47 A;  3IVQ A;  2L0B A;  2LGG A;  2YT5 A;  3HQH A;  3LQI A;  2LRI C;  3VK6 A;  2YQL A;  1WEO A;  5C11 A;  3GL6 A;  5TRB A;  4KG9 A;  1FLK A;  2VPB A;  1WIM A;  3GV4 A;  3MHS A;  2MKE A;  2E61 A;  2XXN A;  5D1L B;  2K4D A;  2HDP A;  1HYJ A;  3U5P A;  2M85 A;  4P5O B;  5SVX A;  4I7C A;  4N3W A;  1BOR A;  2XOC A;  4MSX A;  2YUC A;  1V87 A;  5LKT A;  5K3Q A;  2Y1M A;  1CA4 A;  4NN2 A;  4IC2 A;  1CZY A;  2K16 A;  4GNE A;  1WEU A;  5JG6 A;  4LLB A;  2Y1N A;  2JM3 A;  2KWN A;  5D1K B;  3U5O A;  2JMI A;  2KRE A;  4YBM A;  2M3H A;  5G04 B;  1QSC A;  1K2F A;  2OXQ C;  2VJF B;  4K8U A;  3M99 A;  2M13 A;  3DPL R;  2VPD A;  2YU4 A;  5SVI B;  4S3O C;  3N9N A;  4LJN A;  1VFY A;  4YBT A;  1LB6 A;  2I50 A;  5G05 B;  2L80 A;  2VP7 A;  3PLW A;  5TBN A;  4ZDT A;  4Z0O A;  2KR4 A;  4YBS A;  4LK9 A;  1F62 A;  3DDT A;  4YSI A;  2LXP C;  2EA6 A;  1ZBD B;  3O33 A;  3LDY A;  5AIU A;  5I3L A;  2LGK A;  1WEV A;  2LV9 A;  4O1V A;  2YVR A;  2PUY A;  4GND A;  1G25 A;  4GB0 A;  2FOP A;  4QF2 A;  1IYM A;  2KKX A;  5DIN A;  3HU6 A;  1CZZ A;  2VPE A;  2ECV A;  3EB6 A;  4QF3 A;  4R2Y A;  2PNX A;  3M63 A;  4PPE A;  4AYC B;  1T1H A;  2JMJ A;  2HYE D;  4BBQ A;  3ZJB A;  3E2D A;  3N9P A;  4GWM A;  2MUM A;  4FIP A;  2FOJ A;  4FO9 A;  2XEU A;  3KDE C;  2H0D A;  1WEW A;  4UI9 B;  3HCT A;  5B8D A;  2D8U A;  5B75 A;  4BHW A;  1X4J A;  2NAA A;  1WEN A;  4N4F A;  2Y43 A;  3ASL A;  2CT2 A;  3N9L A;  4W4U A;  2FFW A;  2YYR A;  3FL2 A;  4UP5 A;  2UZG A;  5LKU A;  1D0J A;  2EXU A;  3HSV A;  4V3K C;  2F6N A;  2FUU A;  3HCU A;  1Z60 A;  3RPG C;  5FB0 A;  3ZNI A;  5B76 A;  2G45 A;  1FLL A;  4LKA A;  4WZ3 B;  1F3V B;  2YUR A;  3RPG B;  2LAU A;  2ECG A;  3O70 A;  2EGP A;  4V3L C;  4L7X A;  2KWJ A;  2G43 A;  4WA6 A;  2M6M A;  1DCQ A;  2M1R A;  5B79 A;  1RF3 A;  3N9O A;  5H1V A;  2F1Z A;  3SOX A;  1D0A A;  4TKP B;  1KZZ A;  4GNG A;  2FSA A;  3SHB A;  3KV6 A;  2MD7 B;  2MIQ A;  2YW8 A;  5TDR A;  4A4C A;  2QJ0 A;  4I7D A;  1WEM A;  2YHN A;  2LGL A;  4FJC A;  4F52 B;  5AIT A;  4A49 A;  2ECN A;  1WE9 A;  2CON A;  2FOO A;  4YAD A;  4ZUX U;  5H9M A;  2QIZ A;  2DJA A;  3M7K A;  2ECJ A;  4Z8M A;  2EOD A;  3MQS C;  2DX8 A;  4YAX A;  4H9D A;  1D01 A;  1X4I A;  3JUE A;  3Q1D A;  2CKL B;  4GJH A;  3O36 A;  2XOZ A;  4S3O B;  4X3G A;  4M4E A;  3L1X A;  4B86 C;  4WZ2 A;  1WIL A;  2L75 A;  4A0C D;  1JM7 A;  3DQV R;  2C2L A;  3FM8 C;  3N9Q A;  5DKA A;  3ZVZ B;  5C13 A;  2BAY A;  2MA6 A;  2MT5 A;  3T7L A;  1RMD A;  3IHP A;  3LVR E;  1E4U A;  3LQH A;  2B0O E;  5EYA F;  1JOC A;  3FEH A;  3HQM A;  4UP0 A;  5D1M B;  4GWN A;  3RTR B;  2OWA A;  1MM2 A;  3PUR A;  2LQ6 A;  1LDJ B;  4Z0R A;  2EGM A;  3ZPV E;  2ECI A;  4OGE A;  3HQI A;  3ZPV 1;  2VJF A;  3FAN A;  4YC9 A;  1HYI A;  5SVI A;  1YZE A;  2L43 A;  3HTK C;  1WEE A;  2RR4 A;  2KIZ A;  4GHU A;  3MDB C;  1MM3 A;  5E1T A;  3FAO A;  2JUN A;  1WES A;  2KFT A;  2GKW A;  3O37 A;  1LDK C;  2IDA A;  2KYU A;  3QZV A;  2CRW A;  4YAB A;  2ECT A;  2KE1 A;  2VJE A;  2D8S A;  1WEP A;  4CCG X;  3MHH A;  5FEY A;  2P57 A;  3N9M A;  3KV5 A;  2JMD A;  3SOW A;  4F1P A;  4AP4 A;  4AYC A;  4C9Z A;  4R7E A;  2KGI A;  2F42 A;  2QIC A;  2E6S A;  2LN0 A;  4YAT A;  4QQ4 A;  1VYX A;  4I7B A;  3LVQ E;  1MBM A;  1WGM A;  1JM7 B;  2LGV A; 
#chains in the Genus database with same CATH homology
 5KH9 A;  3IVV A;  5LCW B;  1FP0 A;  5B78 A;  1Z2Q A;  3ZTG A;  3ZYQ A;  2LDR A;  2CSZ A;  2YQM A;  3HQL A;  4L58 A;  2MA5 A;  1X4U A;  2YSM A;  2ZET C;  4LAD B;  3PUQ A;  4CA1 A;  1N87 A;  2MNZ A;  3EB5 A;  4O64 A;  2G6Q A;  2H0D B;  2YHO A;  2F6J A;  3LRQ A;  3C5K A;  2F1W A;  1LB4 A;  2VPG A;  3KNV A;  3IVB A;  5TDW A;  5FB1 A;  2FUI A;  1U6G B;  3NG2 A;  4IC3 A;  3C6W A;  1DVP A;  5H1U A;  2ECW A;  1FBV A;  2KU3 A;  5B77 A;  4XI1 A;  2C2V S;  1XWH A;  2RI7 A;  3O7A A;  3M62 A;  4MVT A;  2KWO A;  3KQI A;  3LQJ A;  3U5M A;  2VJE B;  5H1T A;  5LKZ A;  2JRJ A;  1D00 A;  3O34 A;  2A25 A;  1WFK A;  3PHD A;  1CHC A;  1VD4 A;  3SOU A;  2KWK A;  3L11 A;  2CSY A;  4PTB A;  2KGG A;  2YRE A;  3L1Z B;  1YY6 A;  4B7Y C;  4R8P K;  2RSD A;  3HCS A;  4GNF A;  2XB1 A;  2K17 A;  2VNF A;  2MNY A;  1CA9 A;  3MQR A;  4A4B A;  2CKL A;  5KH3 A;  1Z6U A;  3I2D A;  5J3X A;  1WEQ A;  3V43 A;  2F1X A;  2K1J A;  4AVX A;  2LXH C;  2F1Y A;  1LB5 A;  3T6R A;  4Q6F A;  5FER A;  4WZ0 A;  2YSJ A;  3U5N A;  2L5U A;  3O35 A;  5TAB A;  4FK5 A;  2CR2 A;  4ZQL A;  5LKX A;  4JJQ A;  2E6R A;  5KH7 A;  2MD8 C;  5G0F A;  1ZMS A;  4AUQ B;  3ZVY A;  2AN6 A;  1L0A A;  3IVQ A;  2L0B A;  2LGG A;  2YT5 A;  3HQH A;  3LQI A;  2LRI C;  3VK6 A;  2YQL A;  1WEO A;  5C11 A;  3GL6 A;  5TRB A;  4KG9 A;  1FLK A;  2VPB A;  1WIM A;  3GV4 A;  3MHS A;  2XXN A;  5D1L B;  2K4D A;  2HDP A;  1HYJ A;  3U5P A;  2M85 A;  4P5O B;  4I7C A;  4N3W A;  1BOR A;  4MSX A;  2YUC A;  1V87 A;  5LKT A;  2Y1M A;  1CA4 A;  4NN2 A;  4IC2 A;  1CZY A;  2K16 A;  4GNE A;  1WEU A;  5JG6 A;  4LLB A;  2Y1N A;  2KWN A;  5D1K B;  3U5O A;  2JMI A;  2KRE A;  4YBM A;  2M3H A;  5G04 B;  1QSC A;  1K2F A;  2OXQ C;  2VJF B;  4K8U A;  3M99 A;  2YU4 A;  2VPD A;  3DPL R;  4S3O C;  3N9N A;  4LJN A;  1VFY A;  4YBT A;  1LB6 A;  2I50 A;  5G05 B;  2L80 A;  2VP7 A;  5TBN A;  4ZDT A;  2KR4 A;  4YBS A;  4LK9 A;  1F62 A;  4YSI A;  2LXP C;  2EA6 A;  1ZBD B;  3O33 A;  5AIU A;  5I3L A;  2LGK A;  1WEV A;  2LV9 A;  4O1V A;  2PUY A;  4GND A;  1G25 A;  4GB0 A;  2FOP A;  4QF2 A;  1IYM A;  5DIN A;  3HU6 A;  1CZZ A;  2VPE A;  2ECV A;  3EB6 A;  4QF3 A;  4R2Y A;  2PNX A;  3M63 A;  4PPE A;  4AYC B;  1T1H A;  2JMJ A;  2HYE D;  4BBQ A;  3ZJB A;  3N9P A;  4GWM A;  2MUM A;  4FIP A;  2FOJ A;  4FO9 A;  2XEU A;  2H0D A;  1WEW A;  4UI9 B;  3HCT A;  5B8D A;  5B75 A;  4BHW A;  1X4J A;  2NAA A;  1WEN A;  4N4F A;  2Y43 A;  3ASL A;  2CT2 A;  3N9L A;  4W4U A;  2YYR A;  3FL2 A;  4UP5 A;  2UZG A;  5LKU A;  1D0J A;  3HSV A;  4V3K C;  2F6N A;  2FUU A;  3HCU A;  1Z60 A;  3RPG C;  5FB0 A;  3ZNI A;  5B76 A;  2G45 A;  1FLL A;  4LKA A;  4WZ3 B;  1F3V B;  2YUR A;  3RPG B;  2ECG A;  3O70 A;  2EGP A;  4V3L C;  4L7X A;  2KWJ A;  2G43 A;  4WA6 A;  2M6M A;  2M1R A;  5B79 A;  1RF3 A;  3N9O A;  5H1V A;  2F1Z A;  3SOX A;  1D0A A;  4TKP B;  1KZZ A;  4GNG A;  2FSA A;  3SHB A;  3KV6 A;  2MD7 B;  2MIQ A;  2YW8 A;  5TDR A;  4A4C A;  2QJ0 A;  4I7D A;  1WEM A;  2YHN A;  2LGL A;  4FJC A;  4F52 B;  5AIT A;  4A49 A;  2ECN A;  1WE9 A;  2FOO A;  4YAD A;  4ZUX U;  5H9M A;  2QIZ A;  2ECJ A;  4Z8M A;  2EOD A;  3MQS C;  2DX8 A;  4YAX A;  1D01 A;  1X4I A;  2CKL B;  4GJH A;  3O36 A;  4S3O B;  4X3G A;  4M4E A;  3L1X A;  4B86 C;  4WZ2 A;  1WIL A;  2L75 A;  4A0C D;  1JM7 A;  3DQV R;  2C2L A;  3N9Q A;  5DKA A;  3ZVZ B;  5C13 A;  2BAY A;  2MA6 A;  2MT5 A;  3T7L A;  1RMD A;  3IHP A;  1E4U A;  3LQH A;  5EYA F;  1JOC A;  3HQM A;  4UP0 A;  5D1M B;  4GWN A;  3RTR B;  1MM2 A;  3PUR A;  2LQ6 A;  1LDJ B;  3ZPV E;  2ECI A;  3HQI A;  3ZPV 1;  2VJF A;  4YC9 A;  1HYI A;  1YZE A;  2L43 A;  3HTK C;  1WEE A;  2KIZ A;  4GHU A;  1MM3 A;  5E1T A;  1WES A;  2KFT A;  2GKW A;  3O37 A;  1LDK C;  2IDA A;  2KYU A;  3QZV A;  4YAB A;  2ECT A;  2KE1 A;  2VJE A;  2D8S A;  1WEP A;  4CCG X;  3MHH A;  5FEY A;  3N9M A;  3KV5 A;  2JMD A;  3SOW A;  4AP4 A;  4AYC A;  4C9Z A;  4R7E A;  2KGI A;  2F42 A;  2QIC A;  2E6S A;  2LN0 A;  4YAT A;  1VYX A;  4I7B A;  1WGM A;  1JM7 B;  2LGV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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