4I7DA

Siah1 bound to synthetic peptide (ace)klrpvamvrp(prk)vr
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
192
structure length
187
Chain Sequence
ANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-based design of covalent siah inhibitors.
pubmed doi rcsb
molecule tags Ligase/ligase inhibitor
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase SIAH1
total genus 45
structure length 187
sequence length 192
chains with identical sequence C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2012-11-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 4i7dA02
3.30.40.10 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Zinc/RING finger domain, C3HC4 (zinc finger) 4i7dA01
2LGVA 1WGMA 2F1XA 5D1LB 3SOUA 4GB0A 5LCWB 2FUUA 2L0BA 4IC3A 5EYAF 1WEMA 1WEWA 4FO9A 2L75A 4BBQA 5LKUA 2L43A 2XEUA 4V3LC 4YBTA 2MIQA 3C6WA 3N9MA 2ECNA 3I2DA 4GNFA 1WEVA 4NN2A 1YY6A 4LLBA 4GWMA 2OXQC 3HQMA 4I7DA 4A4CA 2KREA 5LKTA 4L58A 3HSVA 2K4DA 1FBVA 3LQIA 5C11A 3U5MA 4WA6A 4UP0A 2LXHC 5D1MB 1D00A 4GWNA 4CCGX 2KR4A 3N9OA 2K1JA 1X4JA 4R7EA 2LQ6A 4S3OC 4WZ0A 2YYRA 5D1KB 1U6GB 4TKPB 3L1ZB 3RPGC 2KIZA 5G05B 2FSAA 3LQHA 2CT2A 3HQIA 4R8PK 3MQRA 4JJQA 1WILA 2YHOA 4Z8MA 4GJHA 2KWOA 4K8UA 5LKZA 1JOCA 2I50A 2VPGA 4WZ3B 3MQSC 1WEPA 3HU6A 4BHWA 5TABA 3PURA 1MM2A 4YSIA 2KGIA 3O35A 3HTKC 1FLKA 4P5OB 4A49A 5AIUA 4N3WA 2YSMA 1E4UA 3KNVA 1WENA 4X3GA 4MVTA 2M1RA 4YADA 4GNDA 3O34A 4YBMA 3KQIA 1G25A 2VPEA 5B78A 3O33A 4ZQLA 2HYED 4IC2A 4LJNA 1IYMA 1BORA 5E1TA 3RTRB 3MHHA 2CKLB 1XWHA 5B8DA 2JRJA 2K17A 2RI7A 4AP4A 2IDAA 2H0DB 1Z60A 1D01A 5AITA 2LGLA 5C13A 4LKAA 3IVQA 2A25A 3T6RA 2YQMA 4QF2A 2KWKA 2MA5A 5LKXA 2VJFB 5B75A 2MNZA 5B77A 4YBSA 2QJ0A 3V43A 2F1YA 1X4IA 3SOWA 2KWNA 3SOXA 4B7YC 5H9MA 3QZVA 1CHCA 1LB4A 2LDRA 3DQVR 1WESA 2M3HA 2ECTA 4L7XA 1LB6A 2D8SA 2ECVA 2MD7B 3L1XA 2EGPA 3DPLR 2E6SA 4GNEA 2ECGA 3KV5A 4B86C 2KWJA 3N9LA 1CA4A 3ZPV1 3C5KA 5I3LA 1RMDA 2UZGA 2JMDA 4UI9B 2ZETC 3HCSA 2FUIA 3U5OA 1WIMA 5G04B 3SHBA 1VYXA 2G43A 4FJCA 2PUYA 1L0AA 2XB1A 3ZTGA 3HQHA 3FL2A 2CKLA 4PPEA 1QSCA 5KH9A 1RF3A 4GHUA 2BAYA 2LV9A 2H0DA 4F52B 2YT5A 5FERA 2Y1NA 2CSZA 2ECWA 3M63A 2YW8A 4LK9A 2K16A 2LGKA 3T7LA 3ZNIA 1LDJB 2LN0A 2VJFA 1DVPA 4YAXA 1VD4A 2G45A 2GKWA 4QF3A 1WEOA 2MNYA 2LXPC 2F1ZA 2YUCA 1HYIA 4AYCB 5KH3A 2VP7A 4R2YA 1Z2QA 2RSDA 3EB6A 2HDPA 4O64A 1CZYA 4ZDTA 4CA1A 2M85A 4AVXA 4W4UA 2E6RA 1V87A 3ASLA 4ZUXU 2LGGA 4PTBA 3PHDA 1CZZA 2KE1A 3GV4A 5J3XA 5B79A 2C2VS 2F1WA 2KU3A 1X4UA 4I7BA 4A4BA 1T1HA 4I7CA 3U5NA 1MM3A 2YREA 4YABA 2G6QA 3M99A 5B76A 3HQLA 2FOJA 1LDKC 2VPBA 2XXNA 2KFTA 5FEYA 3HCUA 1N87A 1JM7B 4GNGA 5FB1A 4KG9A 5TRBA 3KV6A 3LQJA 3N9QA 4YC9A 1HYJA 4C9ZA 1YZEA 2FOOA 4YATA 1VFYA 3N9PA 2L5UA 5H1TA 4FIPA 3O70A 3ZYQA 4V3KC 2VJEB 4A0CD 4LADB 1WFKA 3ZVYA 4FK5A 3LRQA 4S3OB 5TBNA 3PUQA 1KZZA 2JMIA 5TDWA 3RPGB 1D0JA 2ECIA 3HCTA 2ECJA 3O36A 1WEUA 4AYCA 2PNXA 3O37A 5H1VA 2MA6A 2EA6A 2L80A 2MUMA 4AUQB 1FLLA 2VNFA 2EODA 3N9NA 2KYUA 3IVVA 4N4FA 5KH7A 3NG2A 2QICA 3ZJBA 1LB5A 2DX8A 4WZ2A 1ZBDB 2AN6A 2MD8C 2M6MA 2LRIC 2JMJA 1Z6UA 2Y1MA 3VK6A 4XI1A 1F3VB 3IHPA 1CA9A 3M62A 5TDRA 5DINA 5H1UA 2YQLA 2KGGA 2F42A 2QIZA 5FB0A 3O7AA 3L11A 2YHNA 3U5PA 4MSXA 1ZMSA 2YU4A 1WEEA 1F62A 5JG6A 1K2FA 1JM7A 1WE9A 4O1VA 3GL6A 2C2LA 2YSJA 1D0AA 2NAAA 2CR2A 3IVBA 2FOPA 2MT5A 4UP5A 2YURA 2F6NA 5DKAA 3ZPVE 2VJEA 1FP0A 2VPDA 3MHSA 1WEQA 3EB5A 2F6JA 2Y43A 4M4EA 4Q6FA 3ZVZB 2CSYA 5G0FA
chains in the Genus database with same CATH superfamily
2LGVA 1WGMA 2F1XA 5D1LB 3SOUA 4GB0A 5LCWB 2FUUA 2CRRA 2L0BA 3LVQE 4IC3A 5EYAF 1WEMA 1WEWA 4FO9A 2L75A 4BBQA 5LKUA 2L43A 2XEUA 4V3LC 4YBTA 2MIQA 3C6WA 3N9MA 2ECNA 3I2DA 4GNFA 1WEVA 4NN2A 1YY6A 2DJAA 4GWMA 4LLBA 2OXQC 2CRWA 3HQMA 4I7DA 4A4CA 2KREA 5LKTA 4L58A 3HSVA 2K4DA 1MBMA 1FBVA 3LQIA 5C11A 3U5MA 2EGMA 2CSVA 4WA6A 4UP0A 2LXHC 3SUBA 5D1MB 2E61A 1D00A 3H7HA 4GWNA 4CCGX 2KR4A 3N9OA 2K1JA 1X4JA 4R7EA 2LQ6A 4S3OC 4WZ0A 2YYRA 5D1KB 1U6GB 4TKPB 3L1ZB 3RPGC 2KIZA 5G05B 3FAOA 2FSAA 3LQHA 2CT2A 3HQIA 4R8PK 3MQRA 4JJQA 1WILA 2YHOA 4Z8MA 4GJHA 2KWOA 4K8UA 4QQ4A 5LKZA 1JOCA 2I50A 2VPGA 4WZ3B 3MQSC 1WEPA 3HU6A 2IQJA 4BHWA 3MDBC 5TABA 3PURA 1MM2A 4YSIA 2KGIA 3O35A 3HTKC 1FLKA 4P5OB 4A49A 5AIUA 4N3WA 2YSMA 1E4UA 5SVIB 3KNVA 1WENA 4X3GA 4MVTA 2M1RA 4YADA 4GNDA 5K3QA 3O34A 4YBMA 3KQIA 1G25A 2VPEA 5B78A 3O33A 4ZQLA 2HYED 2M13A 4IC2A 4LJNA 2D8UA 5SVYA 1IYMA 1BORA 5E1TA 3RTRB 3MHHA 2CKLB 1XWHA 5B8DA 2JRJA 2K17A 2RI7A 4AP4A 2IDAA 2H0DB 3FJUB 1Z60A 1D01A 5AITA 2CONA 2LGLA 5C13A 4LKAA 3IVQA 2A25A 3T6RA 2YQMA 2XOYA 1DCQA 4QF2A 4OGEA 2KWKA 4Z0RA 2MA5A 5LKXA 2VJFB 4O62A 5B75A 2MNZA 5B77A 4YBSA 2QJ0A 3V43A 2F1YA 1X4IA 3SOWA 2KWNA 3SOXA 4B7YC 5H9MA 3QZVA 1CHCA 1LB4A 2LDRA 3DQVR 1WESA 2M3HA 2ECTA 4L7XA 1LB6A 2D8SA 4F1PA 2ECVA 2MD7B 3L1XA 2EGPA 3DPLR 2E6SA 4GNEA 2ECGA 3KV5A 4B86C 2KWJA 5SVIA 3N9LA 2MKEA 3Q1DA 1CA4A 3ZPV1 2EXUA 3C5KA 3DWDA 5I3LA 1RMDA 3LJUX 2UZGA 2JMDA 4H9DA 4UI9B 2ZETC 3HCSA 2FUIA 3U5OA 1WIMA 5G04B 3SHBA 1VYXA 2G43A 4FJCA 2PUYA 1L0AA 2XB1A 3ZTGA 3HQHA 3FL2A 2CKLA 4PPEA 3PLWA 1QSCA 5KH9A 1RF3A 4GHUA 2XP0A 2BAYA 2LV9A 2H0DA 4F52B 2YT5A 5FERA 2Y1NA 2CSZA 2ECWA 3M63A 2YW8A 4LK9A 2K16A 2LGKA 3T7LA 3ZNIA 1LDJB 2LN0A 2VJFA 1DVPA 4YAXA 1VD4A 2G45A 2GKWA 4QF3A 1WEOA 2MNYA 2LXPC 2F1ZA 3LVRE 2YUCA 1HYIA 4AYCB 5KH3A 2VP7A 4R2YA 1Z2QA 2RSDA 3EB6A 2HDPA 4O64A 3E2DA 1CZYA 4ZDTA 4CA1A 2JUNA 2M85A 4AVXA 4W4UA 2E6RA 1V87A 3ASLA 4ZUXU 2LGGA 4PTBA 2LAUA 3PHDA 1CZZA 2KE1A 3GV4A 5J3XA 5B79A 2DSMA 3FEHA 2C2VS 2XOZA 2F1WA 2KKYA 2FD4A 5SVXA 2RR4A 2KU3A 1X4UA 4I7BA 4A4BA 1T1HA 4I7CA 3U5NA 1MM3A 2YREA 4YABA 3LDYA 2G6QA 3M99A 5B76A 3HQLA 2FOJA 1LDKC 2VPBA 2XXNA 2KFTA 5FEYA 3HCUA 1N87A 1JM7B 4GNGA 5FB1A 4KG9A 5TRBA 3KV6A 3LQJA 3N9QA 4YC9A 1HYJA 4C9ZA 1YZEA 2FOOA 2P57A 4YATA 1VFYA 3N9PA 2L5UA 5H1TA 4FIPA 3O70A 3ZYQA 4V3KC 2VJEB 4A0CD 4LADB 1WFKA 3ZVYA 4FK5A 3DDTA 3LRQA 4S3OB 5TBNA 3PUQA 1KZZA 2JMIA 5TDWA 3RPGB 1D0JA 2ECIA 3HCTA 2ECJA 3O36A 1WEUA 4AYCA 2PNXA 3O37A 3M7KA 5H1VA 2MA6A 2EA6A 2L80A 2MUMA 4AUQB 1FLLA 2VNFA 2EODA 3N9NA 2KYUA 3KDEC 3IVVA 4Z0OA 4N4FA 5KH7A 3NG2A 2QICA 3ZJBA 1LB5A 2DX8A 4WZ2A 1ZBDB 2AN6A 3O47A 2M6MA 2YVRA 2KKXA 2LRIC 2MD8C 2JMJA 1Z6UA 2Y1MA 3VK6A 4XI1A 1F3VB 3IHPA 1CA9A 3M62A 5TDRA 5DINA 5H1UA 2XOCA 2YQLA 2KGGA 2F42A 2QIZA 5FB0A 3O7AA 3L11A 2YHNA 3U5PA 4MSXA 1ZMSA 2L7PA 2YU4A 1WEEA 2JM3A 1F62A 5JG6A 1K2FA 1JM7A 3JUEA 1WE9A 4O1VA 3FANA 3GL6A 2C2LA 2YSJA 1D0AA 3FM8C 3T9KA 2NAAA 2B0OE 2CR2A 3IVBA 2FOPA 2MT5A 4UP5A 2YURA 2F6NA 5DKAA 3ZPVE 2OWAA 2VJEA 1FP0A 2VPDA 3MHSA 1WEQA 3EB5A 2F6JA 2Y43A 4M4EA 4Q6FA 2FFWA 3ZVZB 2CSYA 4OGCA 5G0FA
chains in the Genus database with same CATH topology
2LGVA 1WGMA 2F1XA 5D1LB 3SOUA 4GB0A 5LCWB 2FUUA 2L0BA 4IC3A 5EYAF 1WEMA 1WEWA 4FO9A 2L75A 4BBQA 5LKUA 2L43A 2XEUA 4V3LC 4YBTA 2MIQA 3C6WA 3N9MA 2ECNA 3I2DA 4GNFA 1WEVA 4NN2A 1YY6A 4LLBA 4GWMA 2OXQC 3HQMA 4I7DA 4A4CA 2KREA 5LKTA 4L58A 3HSVA 2K4DA 1FBVA 3LQIA 5C11A 3U5MA 4WA6A 4UP0A 2LXHC 5D1MB 1D00A 4GWNA 4CCGX 2KR4A 3N9OA 2K1JA 1X4JA 4R7EA 2LQ6A 4S3OC 4WZ0A 2YYRA 5D1KB 1U6GB 4TKPB 3L1ZB 3RPGC 2KIZA 5G05B 2FSAA 3LQHA 2CT2A 3HQIA 4R8PK 3MQRA 4JJQA 1WILA 2YHOA 4Z8MA 4GJHA 2KWOA 4K8UA 5LKZA 1JOCA 2I50A 2VPGA 4WZ3B 3MQSC 1WEPA 3HU6A 4BHWA 5TABA 3PURA 1MM2A 4YSIA 2KGIA 3O35A 3HTKC 1FLKA 4P5OB 4A49A 5AIUA 4N3WA 2YSMA 1E4UA 3KNVA 1WENA 4X3GA 4MVTA 2M1RA 4YADA 4GNDA 3O34A 4YBMA 3KQIA 1G25A 2VPEA 5B78A 3O33A 4ZQLA 2HYED 4IC2A 4LJNA 1IYMA 1BORA 5E1TA 3RTRB 3MHHA 2CKLB 1XWHA 5B8DA 2JRJA 2K17A 2RI7A 4AP4A 2IDAA 2H0DB 1Z60A 1D01A 5AITA 2LGLA 5C13A 4LKAA 3IVQA 2A25A 3T6RA 2YQMA 4QF2A 2KWKA 2MA5A 5LKXA 2VJFB 5B75A 2MNZA 5B77A 4YBSA 2QJ0A 3V43A 2F1YA 1X4IA 3SOWA 2KWNA 3SOXA 4B7YC 5H9MA 3QZVA 1CHCA 1LB4A 2LDRA 3DQVR 1WESA 2M3HA 2ECTA 4L7XA 1LB6A 2D8SA 2ECVA 2MD7B 3L1XA 2EGPA 3DPLR 2E6SA 4GNEA 2ECGA 3KV5A 4B86C 2KWJA 3N9LA 1CA4A 3ZPV1 3C5KA 5I3LA 1RMDA 2UZGA 2JMDA 4UI9B 2ZETC 3HCSA 2FUIA 3U5OA 1WIMA 5G04B 3SHBA 1VYXA 2G43A 4FJCA 2PUYA 1L0AA 2XB1A 3ZTGA 3HQHA 3FL2A 2CKLA 4PPEA 1QSCA 5KH9A 1RF3A 4GHUA 2BAYA 2LV9A 2H0DA 4F52B 2YT5A 5FERA 2Y1NA 2CSZA 2ECWA 3M63A 2YW8A 4LK9A 2K16A 2LGKA 3T7LA 3ZNIA 1LDJB 2LN0A 2VJFA 1DVPA 4YAXA 1VD4A 2G45A 2GKWA 4QF3A 1WEOA 2MNYA 2LXPC 2F1ZA 2YUCA 1HYIA 4AYCB 5KH3A 2VP7A 4R2YA 1Z2QA 2RSDA 3EB6A 2HDPA 4O64A 1CZYA 4ZDTA 4CA1A 2M85A 4AVXA 4W4UA 2E6RA 1V87A 3ASLA 4ZUXU 2LGGA 4PTBA 3PHDA 1CZZA 2KE1A 3GV4A 5J3XA 5B79A 2C2VS 2F1WA 2KU3A 1X4UA 4I7BA 4A4BA 1T1HA 4I7CA 3U5NA 1MM3A 2YREA 4YABA 2G6QA 3M99A 5B76A 3HQLA 2FOJA 1LDKC 2VPBA 2XXNA 2KFTA 5FEYA 3HCUA 1N87A 1JM7B 4GNGA 5FB1A 4KG9A 5TRBA 3KV6A 3LQJA 3N9QA 4YC9A 1HYJA 4C9ZA 1YZEA 2FOOA 4YATA 1VFYA 3N9PA 2L5UA 5H1TA 4FIPA 3O70A 3ZYQA 4V3KC 2VJEB 4A0CD 4LADB 1WFKA 3ZVYA 4FK5A 3LRQA 4S3OB 5TBNA 3PUQA 1KZZA 2JMIA 5TDWA 3RPGB 1D0JA 2ECIA 3HCTA 2ECJA 3O36A 1WEUA 4AYCA 2PNXA 3O37A 5H1VA 2MA6A 2EA6A 2L80A 2MUMA 4AUQB 1FLLA 2VNFA 2EODA 3N9NA 2KYUA 3IVVA 4N4FA 5KH7A 3NG2A 2QICA 3ZJBA 1LB5A 2DX8A 4WZ2A 1ZBDB 2AN6A 2MD8C 2M6MA 2LRIC 2JMJA 1Z6UA 2Y1MA 3VK6A 4XI1A 1F3VB 3IHPA 1CA9A 3M62A 5TDRA 5DINA 5H1UA 2YQLA 2KGGA 2F42A 2QIZA 5FB0A 3O7AA 3L11A 2YHNA 3U5PA 4MSXA 1ZMSA 2YU4A 1WEEA 1F62A 5JG6A 1K2FA 1JM7A 1WE9A 4O1VA 3GL6A 2C2LA 2YSJA 1D0AA 2NAAA 2CR2A 3IVBA 2FOPA 2MT5A 4UP5A 2YURA 2F6NA 5DKAA 3ZPVE 2VJEA 1FP0A 2VPDA 3MHSA 1WEQA 3EB5A 2F6JA 2Y43A 4M4EA 4Q6FA 3ZVZB 2CSYA 5G0FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LGV A;  1WGM A;  2F1X A;  5D1L B;  3SOU A;  4GB0 A;  5LCW B;  2FUU A;  2L0B A;  4IC3 A;  5EYA F;  1WEM A;  1WEW A;  4FO9 A;  2L75 A;  4BBQ A;  5LKU A;  2L43 A;  2XEU A;  4V3L C;  4YBT A;  2MIQ A;  3C6W A;  3N9M A;  2ECN A;  3I2D A;  4GNF A;  1WEV A;  4NN2 A;  1YY6 A;  4LLB A;  4GWM A;  2OXQ C;  3HQM A;  4I7D A;  4A4C A;  2KRE A;  5LKT A;  4L58 A;  3HSV A;  2K4D A;  1FBV A;  3LQI A;  5C11 A;  3U5M A;  4WA6 A;  4UP0 A;  2LXH C;  5D1M B;  1D00 A;  4GWN A;  4CCG X;  2KR4 A;  3N9O A;  2K1J A;  1X4J A;  4R7E A;  2LQ6 A;  4S3O C;  4WZ0 A;  2YYR A;  5D1K B;  1U6G B;  4TKP B;  3L1Z B;  3RPG C;  2KIZ A;  5G05 B;  2FSA A;  3LQH A;  2CT2 A;  3HQI A;  4R8P K;  3MQR A;  4JJQ A;  1WIL A;  2YHO A;  4Z8M A;  4GJH A;  2KWO A;  4K8U A;  5LKZ A;  1JOC A;  2I50 A;  2VPG A;  4WZ3 B;  3MQS C;  1WEP A;  3HU6 A;  4BHW A;  5TAB A;  3PUR A;  1MM2 A;  4YSI A;  2KGI A;  3O35 A;  3HTK C;  1FLK A;  4P5O B;  4A49 A;  5AIU A;  4N3W A;  2YSM A;  1E4U A;  3KNV A;  1WEN A;  4X3G A;  4MVT A;  2M1R A;  4YAD A;  4GND A;  3O34 A;  4YBM A;  3KQI A;  1G25 A;  2VPE A;  5B78 A;  3O33 A;  4ZQL A;  2HYE D;  4IC2 A;  4LJN A;  1IYM A;  1BOR A;  5E1T A;  3RTR B;  3MHH A;  2CKL B;  1XWH A;  5B8D A;  2JRJ A;  2K17 A;  2RI7 A;  4AP4 A;  2IDA A;  2H0D B;  1Z60 A;  1D01 A;  5AIT A;  2LGL A;  5C13 A;  4LKA A;  3IVQ A;  2A25 A;  3T6R A;  2YQM A;  4QF2 A;  2KWK A;  2MA5 A;  5LKX A;  2VJF B;  5B75 A;  2MNZ A;  5B77 A;  4YBS A;  2QJ0 A;  3V43 A;  2F1Y A;  1X4I A;  3SOW A;  2KWN A;  3SOX A;  4B7Y C;  5H9M A;  3QZV A;  1CHC A;  1LB4 A;  2LDR A;  3DQV R;  1WES A;  2M3H A;  2ECT A;  4L7X A;  1LB6 A;  2D8S A;  2ECV A;  2MD7 B;  3L1X A;  2EGP A;  3DPL R;  2E6S A;  4GNE A;  2ECG A;  3KV5 A;  4B86 C;  2KWJ A;  3N9L A;  1CA4 A;  3ZPV 1;  3C5K A;  5I3L A;  1RMD A;  2UZG A;  2JMD A;  4UI9 B;  2ZET C;  3HCS A;  2FUI A;  3U5O A;  1WIM A;  5G04 B;  3SHB A;  1VYX A;  2G43 A;  4FJC A;  2PUY A;  1L0A A;  2XB1 A;  3ZTG A;  3HQH A;  3FL2 A;  2CKL A;  4PPE A;  1QSC A;  5KH9 A;  1RF3 A;  4GHU A;  2BAY A;  2LV9 A;  2H0D A;  4F52 B;  2YT5 A;  5FER A;  2Y1N A;  2CSZ A;  2ECW A;  3M63 A;  2YW8 A;  4LK9 A;  2K16 A;  2LGK A;  3T7L A;  3ZNI A;  1LDJ B;  2LN0 A;  2VJF A;  1DVP A;  4YAX A;  1VD4 A;  2G45 A;  2GKW A;  4QF3 A;  1WEO A;  2MNY A;  2LXP C;  2F1Z A;  2YUC A;  1HYI A;  4AYC B;  5KH3 A;  2VP7 A;  4R2Y A;  1Z2Q A;  2RSD A;  3EB6 A;  2HDP A;  4O64 A;  1CZY A;  4ZDT A;  4CA1 A;  2M85 A;  4AVX A;  4W4U A;  2E6R A;  1V87 A;  3ASL A;  4ZUX U;  2LGG A;  4PTB A;  3PHD A;  1CZZ A;  2KE1 A;  3GV4 A;  5J3X A;  5B79 A;  2C2V S;  2F1W A;  2KU3 A;  1X4U A;  4I7B A;  4A4B A;  1T1H A;  4I7C A;  3U5N A;  1MM3 A;  2YRE A;  4YAB A;  2G6Q A;  3M99 A;  5B76 A;  3HQL A;  2FOJ A;  1LDK C;  2VPB A;  2XXN A;  2KFT A;  5FEY A;  3HCU A;  1N87 A;  1JM7 B;  4GNG A;  5FB1 A;  4KG9 A;  5TRB A;  3KV6 A;  3LQJ A;  3N9Q A;  4YC9 A;  1HYJ A;  4C9Z A;  1YZE A;  2FOO A;  4YAT A;  1VFY A;  3N9P A;  2L5U A;  5H1T A;  4FIP A;  3O70 A;  3ZYQ A;  4V3K C;  2VJE B;  4A0C D;  4LAD B;  1WFK A;  3ZVY A;  4FK5 A;  3LRQ A;  4S3O B;  5TBN A;  3PUQ A;  1KZZ A;  2JMI A;  5TDW A;  3RPG B;  1D0J A;  2ECI A;  3HCT A;  2ECJ A;  3O36 A;  1WEU A;  4AYC A;  2PNX A;  3O37 A;  5H1V A;  2MA6 A;  2EA6 A;  2L80 A;  2MUM A;  4AUQ B;  1FLL A;  2VNF A;  2EOD A;  3N9N A;  2KYU A;  3IVV A;  4N4F A;  5KH7 A;  3NG2 A;  2QIC A;  3ZJB A;  1LB5 A;  2DX8 A;  4WZ2 A;  1ZBD B;  2AN6 A;  2MD8 C;  2M6M A;  2LRI C;  2JMJ A;  1Z6U A;  2Y1M A;  3VK6 A;  4XI1 A;  1F3V B;  3IHP A;  1CA9 A;  3M62 A;  5TDR A;  5DIN A;  5H1U A;  2YQL A;  2KGG A;  2F42 A;  2QIZ A;  5FB0 A;  3O7A A;  3L11 A;  2YHN A;  3U5P A;  4MSX A;  1ZMS A;  2YU4 A;  1WEE A;  1F62 A;  5JG6 A;  1K2F A;  1JM7 A;  1WE9 A;  4O1V A;  3GL6 A;  2C2L A;  2YSJ A;  1D0A A;  2NAA A;  2CR2 A;  3IVB A;  2FOP A;  2MT5 A;  4UP5 A;  2YUR A;  2F6N A;  5DKA A;  3ZPV E;  2VJE A;  1FP0 A;  2VPD A;  3MHS A;  1WEQ A;  3EB5 A;  2F6J A;  2Y43 A;  4M4E A;  4Q6F A;  3ZVZ B;  2CSY A;  5G0F A; 
#chains in the Genus database with same CATH topology
 2LGV A;  1WGM A;  2F1X A;  5D1L B;  3SOU A;  4GB0 A;  5LCW B;  2FUU A;  2CRR A;  2L0B A;  3LVQ E;  4IC3 A;  5EYA F;  1WEM A;  1WEW A;  4FO9 A;  2L75 A;  4BBQ A;  5LKU A;  2L43 A;  2XEU A;  4V3L C;  4YBT A;  2MIQ A;  3C6W A;  3N9M A;  2ECN A;  3I2D A;  4GNF A;  1WEV A;  4NN2 A;  1YY6 A;  2DJA A;  4GWM A;  4LLB A;  2OXQ C;  2CRW A;  3HQM A;  4I7D A;  4A4C A;  2KRE A;  5LKT A;  4L58 A;  3HSV A;  2K4D A;  1MBM A;  1FBV A;  3LQI A;  5C11 A;  3U5M A;  2EGM A;  2CSV A;  4WA6 A;  4UP0 A;  2LXH C;  3SUB A;  5D1M B;  2E61 A;  1D00 A;  3H7H A;  4GWN A;  4CCG X;  2KR4 A;  3N9O A;  2K1J A;  1X4J A;  4R7E A;  2LQ6 A;  4S3O C;  4WZ0 A;  2YYR A;  5D1K B;  1U6G B;  4TKP B;  3L1Z B;  3RPG C;  2KIZ A;  5G05 B;  3FAO A;  2FSA A;  3LQH A;  2CT2 A;  3HQI A;  4R8P K;  3MQR A;  4JJQ A;  1WIL A;  2YHO A;  4Z8M A;  4GJH A;  2KWO A;  4K8U A;  4QQ4 A;  5LKZ A;  1JOC A;  2I50 A;  2VPG A;  4WZ3 B;  3MQS C;  1WEP A;  3HU6 A;  2IQJ A;  4BHW A;  3MDB C;  5TAB A;  3PUR A;  1MM2 A;  4YSI A;  2KGI A;  3O35 A;  3HTK C;  1FLK A;  4P5O B;  4A49 A;  5AIU A;  4N3W A;  2YSM A;  1E4U A;  5SVI B;  3KNV A;  1WEN A;  4X3G A;  4MVT A;  2M1R A;  4YAD A;  4GND A;  5K3Q A;  3O34 A;  4YBM A;  3KQI A;  1G25 A;  2VPE A;  5B78 A;  3O33 A;  4ZQL A;  2HYE D;  2M13 A;  4IC2 A;  4LJN A;  2D8U A;  5SVY A;  1IYM A;  1BOR A;  5E1T A;  3RTR B;  3MHH A;  2CKL B;  1XWH A;  5B8D A;  2JRJ A;  2K17 A;  2RI7 A;  4AP4 A;  2IDA A;  2H0D B;  3FJU B;  1Z60 A;  1D01 A;  5AIT A;  2CON A;  2LGL A;  5C13 A;  4LKA A;  3IVQ A;  2A25 A;  3T6R A;  2YQM A;  2XOY A;  1DCQ A;  4QF2 A;  4OGE A;  2KWK A;  4Z0R A;  2MA5 A;  5LKX A;  2VJF B;  4O62 A;  5B75 A;  2MNZ A;  5B77 A;  4YBS A;  2QJ0 A;  3V43 A;  2F1Y A;  1X4I A;  3SOW A;  2KWN A;  3SOX A;  4B7Y C;  5H9M A;  3QZV A;  1CHC A;  1LB4 A;  2LDR A;  3DQV R;  1WES A;  2M3H A;  2ECT A;  4L7X A;  1LB6 A;  2D8S A;  4F1P A;  2ECV A;  2MD7 B;  3L1X A;  2EGP A;  3DPL R;  2E6S A;  4GNE A;  2ECG A;  3KV5 A;  4B86 C;  2KWJ A;  5SVI A;  3N9L A;  2MKE A;  3Q1D A;  1CA4 A;  3ZPV 1;  2EXU A;  3C5K A;  3DWD A;  5I3L A;  1RMD A;  3LJU X;  2UZG A;  2JMD A;  4H9D A;  4UI9 B;  2ZET C;  3HCS A;  2FUI A;  3U5O A;  1WIM A;  5G04 B;  3SHB A;  1VYX A;  2G43 A;  4FJC A;  2PUY A;  1L0A A;  2XB1 A;  3ZTG A;  3HQH A;  3FL2 A;  2CKL A;  4PPE A;  3PLW A;  1QSC A;  5KH9 A;  1RF3 A;  4GHU A;  2XP0 A;  2BAY A;  2LV9 A;  2H0D A;  4F52 B;  2YT5 A;  5FER A;  2Y1N A;  2CSZ A;  2ECW A;  3M63 A;  2YW8 A;  4LK9 A;  2K16 A;  2LGK A;  3T7L A;  3ZNI A;  1LDJ B;  2LN0 A;  2VJF A;  1DVP A;  4YAX A;  1VD4 A;  2G45 A;  2GKW A;  4QF3 A;  1WEO A;  2MNY A;  2LXP C;  2F1Z A;  3LVR E;  2YUC A;  1HYI A;  4AYC B;  5KH3 A;  2VP7 A;  4R2Y A;  1Z2Q A;  2RSD A;  3EB6 A;  2HDP A;  4O64 A;  3E2D A;  1CZY A;  4ZDT A;  4CA1 A;  2JUN A;  2M85 A;  4AVX A;  4W4U A;  2E6R A;  1V87 A;  3ASL A;  4ZUX U;  2LGG A;  4PTB A;  2LAU A;  3PHD A;  1CZZ A;  2KE1 A;  3GV4 A;  5J3X A;  5B79 A;  2DSM A;  3FEH A;  2C2V S;  2XOZ A;  2F1W A;  2KKY A;  2FD4 A;  5SVX A;  2RR4 A;  2KU3 A;  1X4U A;  4I7B A;  4A4B A;  1T1H A;  4I7C A;  3U5N A;  1MM3 A;  2YRE A;  4YAB A;  3LDY A;  2G6Q A;  3M99 A;  5B76 A;  3HQL A;  2FOJ A;  1LDK C;  2VPB A;  2XXN A;  2KFT A;  5FEY A;  3HCU A;  1N87 A;  1JM7 B;  4GNG A;  5FB1 A;  4KG9 A;  5TRB A;  3KV6 A;  3LQJ A;  3N9Q A;  4YC9 A;  1HYJ A;  4C9Z A;  1YZE A;  2FOO A;  2P57 A;  4YAT A;  1VFY A;  3N9P A;  2L5U A;  5H1T A;  4FIP A;  3O70 A;  3ZYQ A;  4V3K C;  2VJE B;  4A0C D;  4LAD B;  1WFK A;  3ZVY A;  4FK5 A;  3DDT A;  3LRQ A;  4S3O B;  5TBN A;  3PUQ A;  1KZZ A;  2JMI A;  5TDW A;  3RPG B;  1D0J A;  2ECI A;  3HCT A;  2ECJ A;  3O36 A;  1WEU A;  4AYC A;  2PNX A;  3O37 A;  3M7K A;  5H1V A;  2MA6 A;  2EA6 A;  2L80 A;  2MUM A;  4AUQ B;  1FLL A;  2VNF A;  2EOD A;  3N9N A;  2KYU A;  3KDE C;  3IVV A;  4Z0O A;  4N4F A;  5KH7 A;  3NG2 A;  2QIC A;  3ZJB A;  1LB5 A;  2DX8 A;  4WZ2 A;  1ZBD B;  2AN6 A;  3O47 A;  2M6M A;  2YVR A;  2KKX A;  2LRI C;  2MD8 C;  2JMJ A;  1Z6U A;  2Y1M A;  3VK6 A;  4XI1 A;  1F3V B;  3IHP A;  1CA9 A;  3M62 A;  5TDR A;  5DIN A;  5H1U A;  2XOC A;  2YQL A;  2KGG A;  2F42 A;  2QIZ A;  5FB0 A;  3O7A A;  3L11 A;  2YHN A;  3U5P A;  4MSX A;  1ZMS A;  2L7P A;  2YU4 A;  1WEE A;  2JM3 A;  1F62 A;  5JG6 A;  1K2F A;  1JM7 A;  3JUE A;  1WE9 A;  4O1V A;  3FAN A;  3GL6 A;  2C2L A;  2YSJ A;  1D0A A;  3FM8 C;  3T9K A;  2NAA A;  2B0O E;  2CR2 A;  3IVB A;  2FOP A;  2MT5 A;  4UP5 A;  2YUR A;  2F6N A;  5DKA A;  3ZPV E;  2OWA A;  2VJE A;  1FP0 A;  2VPD A;  3MHS A;  1WEQ A;  3EB5 A;  2F6J A;  2Y43 A;  4M4E A;  4Q6F A;  2FFW A;  3ZVZ B;  2CSY A;  4OGC A;  5G0F A; 
#chains in the Genus database with same CATH homology
 2LGV A;  1WGM A;  2F1X A;  5D1L B;  3SOU A;  4GB0 A;  5LCW B;  2FUU A;  2L0B A;  4IC3 A;  5EYA F;  1WEM A;  1WEW A;  4FO9 A;  2L75 A;  4BBQ A;  5LKU A;  2L43 A;  2XEU A;  4V3L C;  4YBT A;  2MIQ A;  3C6W A;  3N9M A;  2ECN A;  3I2D A;  4GNF A;  1WEV A;  4NN2 A;  1YY6 A;  4LLB A;  4GWM A;  2OXQ C;  3HQM A;  4I7D A;  4A4C A;  2KRE A;  5LKT A;  4L58 A;  3HSV A;  2K4D A;  1FBV A;  3LQI A;  5C11 A;  3U5M A;  4WA6 A;  4UP0 A;  2LXH C;  5D1M B;  1D00 A;  4GWN A;  4CCG X;  2KR4 A;  3N9O A;  2K1J A;  1X4J A;  4R7E A;  2LQ6 A;  4S3O C;  4WZ0 A;  2YYR A;  5D1K B;  1U6G B;  4TKP B;  3L1Z B;  3RPG C;  2KIZ A;  5G05 B;  2FSA A;  3LQH A;  2CT2 A;  3HQI A;  4R8P K;  3MQR A;  4JJQ A;  1WIL A;  2YHO A;  4Z8M A;  4GJH A;  2KWO A;  4K8U A;  5LKZ A;  1JOC A;  2I50 A;  2VPG A;  4WZ3 B;  3MQS C;  1WEP A;  3HU6 A;  4BHW A;  5TAB A;  3PUR A;  1MM2 A;  4YSI A;  2KGI A;  3O35 A;  3HTK C;  1FLK A;  4P5O B;  4A49 A;  5AIU A;  4N3W A;  2YSM A;  1E4U A;  3KNV A;  1WEN A;  4X3G A;  4MVT A;  2M1R A;  4YAD A;  4GND A;  3O34 A;  4YBM A;  3KQI A;  1G25 A;  2VPE A;  5B78 A;  3O33 A;  4ZQL A;  2HYE D;  4IC2 A;  4LJN A;  1IYM A;  1BOR A;  5E1T A;  3RTR B;  3MHH A;  2CKL B;  1XWH A;  5B8D A;  2JRJ A;  2K17 A;  2RI7 A;  4AP4 A;  2IDA A;  2H0D B;  1Z60 A;  1D01 A;  5AIT A;  2LGL A;  5C13 A;  4LKA A;  3IVQ A;  2A25 A;  3T6R A;  2YQM A;  4QF2 A;  2KWK A;  2MA5 A;  5LKX A;  2VJF B;  5B75 A;  2MNZ A;  5B77 A;  4YBS A;  2QJ0 A;  3V43 A;  2F1Y A;  1X4I A;  3SOW A;  2KWN A;  3SOX A;  4B7Y C;  5H9M A;  3QZV A;  1CHC A;  1LB4 A;  2LDR A;  3DQV R;  1WES A;  2M3H A;  2ECT A;  4L7X A;  1LB6 A;  2D8S A;  2ECV A;  2MD7 B;  3L1X A;  2EGP A;  3DPL R;  2E6S A;  4GNE A;  2ECG A;  3KV5 A;  4B86 C;  2KWJ A;  3N9L A;  1CA4 A;  3ZPV 1;  3C5K A;  5I3L A;  1RMD A;  2UZG A;  2JMD A;  4UI9 B;  2ZET C;  3HCS A;  2FUI A;  3U5O A;  1WIM A;  5G04 B;  3SHB A;  1VYX A;  2G43 A;  4FJC A;  2PUY A;  1L0A A;  2XB1 A;  3ZTG A;  3HQH A;  3FL2 A;  2CKL A;  4PPE A;  1QSC A;  5KH9 A;  1RF3 A;  4GHU A;  2BAY A;  2LV9 A;  2H0D A;  4F52 B;  2YT5 A;  5FER A;  2Y1N A;  2CSZ A;  2ECW A;  3M63 A;  2YW8 A;  4LK9 A;  2K16 A;  2LGK A;  3T7L A;  3ZNI A;  1LDJ B;  2LN0 A;  2VJF A;  1DVP A;  4YAX A;  1VD4 A;  2G45 A;  2GKW A;  4QF3 A;  1WEO A;  2MNY A;  2LXP C;  2F1Z A;  2YUC A;  1HYI A;  4AYC B;  5KH3 A;  2VP7 A;  4R2Y A;  1Z2Q A;  2RSD A;  3EB6 A;  2HDP A;  4O64 A;  1CZY A;  4ZDT A;  4CA1 A;  2M85 A;  4AVX A;  4W4U A;  2E6R A;  1V87 A;  3ASL A;  4ZUX U;  2LGG A;  4PTB A;  3PHD A;  1CZZ A;  2KE1 A;  3GV4 A;  5J3X A;  5B79 A;  2C2V S;  2F1W A;  2KU3 A;  1X4U A;  4I7B A;  4A4B A;  1T1H A;  4I7C A;  3U5N A;  1MM3 A;  2YRE A;  4YAB A;  2G6Q A;  3M99 A;  5B76 A;  3HQL A;  2FOJ A;  1LDK C;  2VPB A;  2XXN A;  2KFT A;  5FEY A;  3HCU A;  1N87 A;  1JM7 B;  4GNG A;  5FB1 A;  4KG9 A;  5TRB A;  3KV6 A;  3LQJ A;  3N9Q A;  4YC9 A;  1HYJ A;  4C9Z A;  1YZE A;  2FOO A;  4YAT A;  1VFY A;  3N9P A;  2L5U A;  5H1T A;  4FIP A;  3O70 A;  3ZYQ A;  4V3K C;  2VJE B;  4A0C D;  4LAD B;  1WFK A;  3ZVY A;  4FK5 A;  3LRQ A;  4S3O B;  5TBN A;  3PUQ A;  1KZZ A;  2JMI A;  5TDW A;  3RPG B;  1D0J A;  2ECI A;  3HCT A;  2ECJ A;  3O36 A;  1WEU A;  4AYC A;  2PNX A;  3O37 A;  5H1V A;  2MA6 A;  2EA6 A;  2L80 A;  2MUM A;  4AUQ B;  1FLL A;  2VNF A;  2EOD A;  3N9N A;  2KYU A;  3IVV A;  4N4F A;  5KH7 A;  3NG2 A;  2QIC A;  3ZJB A;  1LB5 A;  2DX8 A;  4WZ2 A;  1ZBD B;  2AN6 A;  2MD8 C;  2M6M A;  2LRI C;  2JMJ A;  1Z6U A;  2Y1M A;  3VK6 A;  4XI1 A;  1F3V B;  3IHP A;  1CA9 A;  3M62 A;  5TDR A;  5DIN A;  5H1U A;  2YQL A;  2KGG A;  2F42 A;  2QIZ A;  5FB0 A;  3O7A A;  3L11 A;  2YHN A;  3U5P A;  4MSX A;  1ZMS A;  2YU4 A;  1WEE A;  1F62 A;  5JG6 A;  1K2F A;  1JM7 A;  1WE9 A;  4O1V A;  3GL6 A;  2C2L A;  2YSJ A;  1D0A A;  2NAA A;  2CR2 A;  3IVB A;  2FOP A;  2MT5 A;  4UP5 A;  2YUR A;  2F6N A;  5DKA A;  3ZPV E;  2VJE A;  1FP0 A;  2VPD A;  3MHS A;  1WEQ A;  3EB5 A;  2F6J A;  2Y43 A;  4M4E A;  4Q6F A;  3ZVZ B;  2CSY A;  5G0F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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