4WJ7 | Genus

Total Genus 35

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	35
sequence length	167
structure length	137
Chain Sequence	PDRLLSDYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEHDAVLSLSAYNVKLAWRDGEDIILRVPIHDIAAVSYVRDDAAHLVVLKTAQDEACCLVILAAESKVAAEELCCLLGQVFQVVY

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Protein binding
source organism	Homo sapiens
publication title	Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations. pubmed doi rcsb
molecule keywords	Malcavernin
total genus	35
structure length	137
sequence length	167
chains with identical sequence	B, C, D
ec nomenclature
pdb deposition date	2014-09-29

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.30.29.30	Mainly Beta	Roll	PH-domain like	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	4wj7A00

2K00A 2R0DA 3ODWA 3OANA 2OQBA 1NU2A 2N0YA 4CYEA 3SNHA 3PVWA 1EGXA 2VRWB 2D10A 4TYZA 2Z0OA 2K2JA 2DX5A 4Z2MB 2R09A 3HK0A 2LULA 2Z0PA 4PQ0A 1DROA 2MKRA 4MK0A 2YF0A 4Z2NA 2VKIA 3GYPA 2DHIA 1W1DA 2Y8FA 1I2HA 3SUZA 1U5DA 3TVVA 1UNPA 2ADZA 2DN6A 4C0AA 2D11A 3RCPA 3QIJA 2ROVA 1FHOA 2J0KA 1FHWA 4ZRJA 5EFXA 1EF1A 2HE7A 2COCA 2KUPA 5JHHA 2YT1A 2LOZA 2OTXA 1FAOA 1V89A 2CY4A 4XWXA 2ROZB 1U5GA 5DHAB 3O96A 4HB2B 4KHBB 2I5FA 1ZM0A 1UEFA 1M7EA 1EVHA 3WA0A 5D27A 4ZRIA 2DYQA 4HAZB 2H7EA 4HB4B 3DXDA 2ZPYA 4GMXB 2XQNM 4K81A 3U7DA 1WGQA 4GN1A 4K17A 1BAKA 1U5FA 1NTYA 3KRXA 5HE2A 4ZRKA 5FI1A 1QQGA 2H7DA 2D9XA 3PEGA 1Q67A 4YONA 1TJ6A 2X18A 3AJ4A 1K5GB 1XKEA 3P7ZA 1BTNA 3V5WA 3UZTA 4DXAB 2DKPA 3ULBA 5D3WA 4GZUA 1MK7B 5C79A 2EC1A 2DLWA 3T06A 2P0DA 1V5PA 2D9YA 2KCJA 4IOYX 2GCLA 2DKQA 4A6FB 4HAWB 4DBBA 1Z87A 3KSYA 3F5RA 1AQCA 3AU4A 2UVMA 1TXDA 2ELAA 4A6FA 1ZSQA 2COAA 1ISNA 1OY2A 2W2XC 3MDBC 5LONB 1UNRA 1X1GA 1U5EA 3SO6A 1DDVA 2P0FA 4Y94A 1H4RA 2L1CA 1XX0A 4P7IA 3HQCA 1V88A 3DXEA 1J0WA 1PMSA 4TKNA 3TW1A 5D3XA 1MIZB 2W2WA 2EJ8A 1X11A 4IAPA 4L6EA 1IRSA 2YS3A 4BBKA 3BJIA 2QKMA 4B6HA 3PP2A 5DI9B 3PZDA 1U29A 1TQZA 5J3YA 3U8ZA 1OMWA 1UNQA 4EKUA 3BINA 3PG7A 1V5UA 1P5TA 1V5MA 2I1JA 2GS0A 3SV1A 3NSUA 3CIKA 3ZVRA 5HE1A 2AEHA 1U2BA 2DHJA 4DX8A 5KQ1A 2P0HA 1MAIA 5C5BB 1GG3A 1MKEA 3ZDTA 2NZ8B 2EMSA 1FOEA 2RLOA 5FI0A 2YSZA 1KI1B 1QC6A 3ULCA 1MPHA 3KZ1A 1WJMA 2DFKA 5C5BA 3TCAA 1E5WA 1LB1A 1I7AA 2DX1A 4A5KA 4MT7A 1H10A 1BWNA 1FB8A 1K5DB 5HE0A 2G35A 2Y8GA 4KHAA 4DX90 2DTCA 5D3VA 1XR0B 1OQNA 1WG7A 4GMVA 4K2OA 2RGNB 3PVLA 2QKLA 1DBHA 2MDXA 4HAXB 1U27A 3A98B 4D0NB 4KHOA 2LKOA 2DHKA 3CXBB 2RVBB 3D8DA 2LYDA 3KRWA 3HW2B 3A8PA 3P6AA 2IFSA 5L81A 3QWMA 2E2XA 2CY5A 4WSFA 5KCVA 2RSGA 2J59M 2YT0A 3ML4A 4PNKA 2ELBA 2MFQA 5C16A 2RNRB 2JP2A 4HHVA 1FHXA 2J0MA 3QBVB 5J3TA 3GYOA 3SYXA 2I5CA 1NI2A 5D3YA 1DDMA 4MY6A 2D9ZA 2LG1A 2HTHB 3ODOA 3FEHA 3FSSA 1UPQA 1X05A 4GXBA 2M38A 5HE3A 4F7GA 1AWEA 2COFA 4H8SA 4IFSA 1ZC3B 1NTVA 4HB3B 3G9WA 4YL8A 3D8FA 3D8EA 1WI1A 3WYFB 4KVGB 2GJYA 4WVFB 3TFMA 4GPTB 1Y19B 2M14A 1P3RA 1UPRA 2W2XD 2YRYA 3M1IB 1XD4A 3MPXA 3LJUX 1SHCA 2Q13A 1B55A 2I1KA 5JP4A 1X86A 1WVHA 4HB0B 1MIXA 3DXCA 1DDWA 1GC6A 2DA0A 1RJ2A 3A8QA 3ODXA 2YS1A 5DHFB 2CODA 2Z0QA 2UZSA 1RRPB 2CRFA 2YVCA 4HAVB 4EJNA 1N3HA 3FM8C 3IVFA 1X1FA 2P8VA 2EMTA 1MK9B 4CHMA 1ZVRA 3PSCA 2D9VA 2PZ1A 2NMBA 1W1GA 2BCJA 3F0WA 2VSZA 1P6SA 4HAUB 5KQ4A 2D4QA 4WJ7A 1FGYA 1M7RA 2DYNA 1KZGA 2N23A 5DH9B 1BTKA 2Y7BA 4EMOA 3X23A 2K2UA 5JHGA 2UZRA 1J19A 1EAZA 1KZ7A 5C6RA 3KY9A 5DIFB 2LOXA 5JLJB 5J3QA 1WJ1A 1W1HA 1PLSA 5GOWB 2D9WA 1LW3A 3N7CA 4HAYB 4K2PA 2FJLA 3PVUA 1Y5OA 4NY0A 4F7HA 2L2IA 5CLLB 1XODA 1ZC4B 3VOQA 2GCJA 4CHJA 2YS5A 1DYNA 1XCGA 2AL6A 4NSWA 2CAYA 4A6KA 3VIAA 2V76A 1V61A 1WGUA 4KAXB 1GC7A 1SGHA 2MWNB 1FGZA 5CLQB 2KGXB 2RUKB 4HATB 3TO1A 5LOPB 4HDOA 2IYBA 2D2QA 4A6HA 3AU5A 4HDQA 2J0JA 4F7UP 1PFJA
chains in the Genus database with same CATH superfamily

2K00A 2R0DA 3ODWA 3OANA 2OQBA 1NU2A 2N0YA 4CYEA 3SNHA 3NWDA 3PVWA 1EGXA 1MI1A 2VRWB 2ZKMX 4QJ5B 2D10A 4TYZA 2Z0OA 2K2JA 3NW8A 3OHMB 2DX5A 4Z2MB 2R09A 3HK0A 2LULA 2Z0PA 4OT1A 4PQ0A 1DROA 2MKRA 4MK0A 2YF0A 4Z2NA 2VKIA 3GYPA 2DHIA 3NWFA 1W1DA 2Y8FA 1I2HA 3SUZA 1U5DA 3TVVA 4QJ4B 1UNPA 2ADZA 2DN6A 4C0AA 2D11A 4OSNA 3RCPA 3QIJA 2ROVA 2RRFA 1FHOA 2J0KA 1FHWA 4ZRJA 5EFXA 1EF1A 2HE7A 2COCA 2KUPA 5JHHA 2YT2A 2YT1A 2LOZA 2OTXA 1FAOA 1V89A 2CY4A 4XWXA 2ROZB 2K8EA 1U5GA 5DHAB 3O96A 4HB2B 4KHBB 2I5FA 1ZM0A 1UEFA 1M7EA 1EVHA 3WA0A 5D27A 4ZRIA 2DYQA 4HAZB 2H7EA 4HB4B 3DXDA 5IRSA 2ZPYA 4GMXB 2XQNM 4K81A 3U7DA 1WGQA 4GN1A 4K17A 1BAKA 1U5FA 1NTYA 3KRXA 5HE2A 4ZRKA 5FI1A 1QQGA 2H7DA 2D9XA 1Q67A 3PEGA 4YONA 1TJ6A 4D6WA 2X18A 3AJ4A 1K5GB 1XKEA 3P7ZA 1BTNA 3V5WA 3UZTA 1T77A 4DXAB 2DKPA 3ULBA 5M4YB 5D3WA 4GZUA 1MK7B 5C79A 2EC1A 4QJ3B 2DLWA 3T06A 3DCXA 2KIEA 2P0DA 1V5PA 2D9YA 2KCJA 5I2SA 4IOYX 2GCLA 2DKQA 4A6FB 4HAWB 4DBBA 1Z87A 3KSYA 3F5RA 1AQCA 3AU4A 2GUMA 2UVMA 1TXDA 4GOUA 2ELAA 4A6FA 1ZSQA 2COAA 1ISNA 1OY2A 2W2XC 3MDBC 5LONB 1UNRA 1X1GA 1U5EA 3SO6A 1DDVA 2P0FA 4Y94A 1H4RA 2Z4DA 2L1CA 4QXAB 1XX0A 2Z14A 3B77A 4P7IA 3HQCA 1V88A 3DXEA 1J0WA 1ZYIA 2Z13A 1PMSA 4TKNA 3TW1A 5D3XA 1MIZB 2W2WA 2EJ8A 1X11A 3NWAA 4IAPA 4L6EA 2KIGA 1IRSA 2YS3A 4BBKA 3BJIA 2QKMA 4B6HA 3PP2A 5DI9B 3PZDA 1U29A 1TQZA 5J3YA 3U8ZA 2FJUB 1OMWA 1UNQA 4EKUA 3BINA 3A58A 1V5UA 3PG7A 1P5TA 1V5MA 2I1JA 2GS0A 3SV1A 3NSUA 3CIKA 3ZVRA 5HE1A 2AEHA 1U2BA 2DHJA 4DX8A 5KQ1A 2P0HA 1MAIA 5C5BB 1GG3A 1MKEA 3ZDTA 2NZ8B 2EMSA 1FOEA 2RLOA 2NBVA 5FI0A 2YSZA 1KI1B 1QC6A 3ULCA 2KUQA 1MPHA 3KZ1A 1WJMA 2DFKA 5C5BA 3TCAA 1E5WA 1LB1A 1I7AA 2DX1A 4A5KA 4MT7A 5LG4B 1H10A 1BWNA 1FB8A 1K5DB 5HE0A 2G35A 3FVCA 2Y8GA 4KHAA 4DX90 2DTCA 4DIXA 5D3VA 1XR0B 5I2MA 1OQNA 1WG7A 4GMVA 4K2OA 2RGNB 3PVLA 2QKLA 1DBHA 2MDXA 4HAXB 1U27A 3A98B 4HSIA 4D0NB 4KHOA 2LKOA 4L1RA 2DHKA 3CXBB 2RVBB 3D8DA 2LYDA 3KRWA 3HW2B 3A8PA 3P6AA 2IFSA 5L81A 3QWMA 2E2XA 2CY5A 4WSFA 5KCVA 2RSGA 2J59M 2YT0A 3ML4A 4PNKA 2ELBA 2MFQA 5C16A 2RNRB 2JP2A 4HHVA 1FHXA 2J0MA 3QBVB 5J3TA 3GYOA 3SYXA 2I5CA 1NI2A 5D3YA 1DDMA 4MY6A 2D9ZA 4CSQA 2LG1A 2HTHB 3ODOA 3FEHA 3FSSA 1UPQA 1X05A 4GXBA 2M38A 5HE3A 4F7GA 1AWEA 2COFA 4H8SA 4IFSA 1ZC3B 1NTVA 4HB3B 3G9WA 4YL8A 3D8FA 3D8EA 1WI1A 3WYFB 4KVGB 2GJYA 4WVFB 3TFMA 4GPTB 1Y19B 2M14A 1P3RA 1UPRA 2W2XD 2YRYA 3M1IB 1XD4A 3MPXA 3LJUX 1SHCA 2Q13A 1B55A 2I1KA 4GNKB 5JP4A 1X86A 1WVHA 4HB0B 1MIXA 3DXCA 1DDWA 1GC6A 2DA0A 1RJ2A 3A8QA 3ODXA 2YS1A 5DHFB 2CODA 2Z0QA 2UZSA 1RRPB 2CRFA 2YVCA 4HAVB 4EJNA 1N3HA 3FM8C 3IVFA 1X1FA 2P8VA 2EMTA 1MK9B 4CHMA 1ZVRA 3PSCA 2D9VA 2PZ1A 2NMBA 1W1GA 3HSAA 2BCJA 3F0WA 2Z59A 3HIEA 2VSZA 1P6SA 4HAUB 5KQ4A 2D4QA 4WJ7A 1FGYA 1M7RA 2DYNA 1KZGA 2N23A 5DH9B 1BTKA 2Y7BA 4EMOA 3X23A 2K2UA 5JHGA 2UZRA 1J19A 1EAZA 1KZ7A 5C6RA 3KY9A 5DIFB 2LOXA 5JLJB 5J3QA 1WJ1A 1W1HA 1PLSA 5GOWB 2D9WA 1LW3A 3N7CA 4HAYB 4K2PA 4KHBA 2FJLA 3PVUA 1Y5OA 4NY0A 4F7HA 2L2IA 5CLLB 1XODA 1ZC4B 3VOQA 2GCJA 4CHJA 2YS5A 1DYNA 2K49A 1XCGA 2AL6A 4NSWA 2CAYA 4A6KA 3VIAA 2V76A 3U12A 1V61A 1WGUA 4KAXB 2R2YA 1GC7A 1SGHA 2MWNB 1FGZA 5CLQB 2KGXB 2KR0A 2RUKB 4HATB 3TO1A 5LOPB 4HDOA 2IYBA 2D2QA 4A6HA 3AU5A 4HDQA 2J0JA 4F7UP 1PFJA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2K00 A;  2R0D A;  3ODW A;  3OAN A;  2OQB A;  1NU2 A;  2N0Y A;  4CYE A;  3SNH A;  3PVW A;  1EGX A;  2VRW B;  2D10 A;  4TYZ A;  2Z0O A;  2K2J A;  2DX5 A;  4Z2M B;  2R09 A;  3HK0 A;  2LUL A;  2Z0P A;  4PQ0 A;  1DRO A;  2MKR A;  4MK0 A;  2YF0 A;  4Z2N A;  2VKI A;  3GYP A;  2DHI A;  1W1D A;  2Y8F A;  1I2H A;  3SUZ A;  1U5D A;  3TVV A;  1UNP A;  2ADZ A;  2DN6 A;  4C0A A;  2D11 A;  3RCP A;  3QIJ A;  2ROV A;  1FHO A;  2J0K A;  1FHW A;  4ZRJ A;  5EFX A;  1EF1 A;  2HE7 A;  2COC A;  2KUP A;  5JHH A;  2YT1 A;  2LOZ A;  2OTX A;  1FAO A;  1V89 A;  2CY4 A;  4XWX A;  2ROZ B;  1U5G A;  5DHA B;  3O96 A;  4HB2 B;  4KHB B;  2I5F A;  1ZM0 A;  1UEF A;  1M7E A;  1EVH A;  3WA0 A;  5D27 A;  4ZRI A;  2DYQ A;  4HAZ B;  2H7E A;  4HB4 B;  3DXD A;  2ZPY A;  4GMX B;  2XQN M;  4K81 A;  3U7D A;  1WGQ A;  4GN1 A;  4K17 A;  1BAK A;  1U5F A;  1NTY A;  3KRX A;  5HE2 A;  4ZRK A;  5FI1 A;  1QQG A;  2H7D A;  2D9X A;  3PEG A;  1Q67 A;  4YON A;  1TJ6 A;  2X18 A;  3AJ4 A;  1K5G B;  1XKE A;  3P7Z A;  1BTN A;  3V5W A;  3UZT A;  4DXA B;  2DKP A;  3ULB A;  5D3W A;  4GZU A;  1MK7 B;  5C79 A;  2EC1 A;  2DLW A;  3T06 A;  2P0D A;  1V5P A;  2D9Y A;  2KCJ A;  4IOY X;  2GCL A;  2DKQ A;  4A6F B;  4HAW B;  4DBB A;  1Z87 A;  3KSY A;  3F5R A;  1AQC A;  3AU4 A;  2UVM A;  1TXD A;  2ELA A;  4A6F A;  1ZSQ A;  2COA A;  1ISN A;  1OY2 A;  2W2X C;  3MDB C;  5LON B;  1UNR A;  1X1G A;  1U5E A;  3SO6 A;  1DDV A;  2P0F A;  4Y94 A;  1H4R A;  2L1C A;  1XX0 A;  4P7I A;  3HQC A;  1V88 A;  3DXE A;  1J0W A;  1PMS A;  4TKN A;  3TW1 A;  5D3X A;  1MIZ B;  2W2W A;  2EJ8 A;  1X11 A;  4IAP A;  4L6E A;  1IRS A;  2YS3 A;  4BBK A;  3BJI A;  2QKM A;  4B6H A;  3PP2 A;  5DI9 B;  3PZD A;  1U29 A;  1TQZ A;  5J3Y A;  3U8Z A;  1OMW A;  1UNQ A;  4EKU A;  3BIN A;  3PG7 A;  1V5U A;  1P5T A;  1V5M A;  2I1J A;  2GS0 A;  3SV1 A;  3NSU A;  3CIK A;  3ZVR A;  5HE1 A;  2AEH A;  1U2B A;  2DHJ A;  4DX8 A;  5KQ1 A;  2P0H A;  1MAI A;  5C5B B;  1GG3 A;  1MKE A;  3ZDT A;  2NZ8 B;  2EMS A;  1FOE A;  2RLO A;  5FI0 A;  2YSZ A;  1KI1 B;  1QC6 A;  3ULC A;  1MPH A;  3KZ1 A;  1WJM A;  2DFK A;  5C5B A;  3TCA A;  1E5W A;  1LB1 A;  1I7A A;  2DX1 A;  4A5K A;  4MT7 A;  1H10 A;  1BWN A;  1FB8 A;  1K5D B;  5HE0 A;  2G35 A;  2Y8G A;  4KHA A;  4DX9 0;  2DTC A;  5D3V A;  1XR0 B;  1OQN A;  1WG7 A;  4GMV A;  4K2O A;  2RGN B;  3PVL A;  2QKL A;  1DBH A;  2MDX A;  4HAX B;  1U27 A;  3A98 B;  4D0N B;  4KHO A;  2LKO A;  2DHK A;  3CXB B;  2RVB B;  3D8D A;  2LYD A;  3KRW A;  3HW2 B;  3A8P A;  3P6A A;  2IFS A;  5L81 A;  3QWM A;  2E2X A;  2CY5 A;  4WSF A;  5KCV A;  2RSG A;  2J59 M;  2YT0 A;  3ML4 A;  4PNK A;  2ELB A;  2MFQ A;  5C16 A;  2RNR B;  2JP2 A;  4HHV A;  1FHX A;  2J0M A;  3QBV B;  5J3T A;  3GYO A;  3SYX A;  2I5C A;  1NI2 A;  5D3Y A;  1DDM A;  4MY6 A;  2D9Z A;  2LG1 A;  2HTH B;  3ODO A;  3FEH A;  3FSS A;  1UPQ A;  1X05 A;  4GXB A;  2M38 A;  5HE3 A;  4F7G A;  1AWE A;  2COF A;  4H8S A;  4IFS A;  1ZC3 B;  1NTV A;  4HB3 B;  3G9W A;  4YL8 A;  3D8F A;  3D8E A;  1WI1 A;  3WYF B;  4KVG B;  2GJY A;  4WVF B;  3TFM A;  4GPT B;  1Y19 B;  2M14 A;  1P3R A;  1UPR A;  2W2X D;  2YRY A;  3M1I B;  1XD4 A;  3MPX A;  3LJU X;  1SHC A;  2Q13 A;  1B55 A;  2I1K A;  5JP4 A;  1X86 A;  1WVH A;  4HB0 B;  1MIX A;  3DXC A;  1DDW A;  1GC6 A;  2DA0 A;  1RJ2 A;  3A8Q A;  3ODX A;  2YS1 A;  5DHF B;  2COD A;  2Z0Q A;  2UZS A;  1RRP B;  2CRF A;  2YVC A;  4HAV B;  4EJN A;  1N3H A;  3FM8 C;  3IVF A;  1X1F A;  2P8V A;  2EMT A;  1MK9 B;  4CHM A;  1ZVR A;  3PSC A;  2D9V A;  2PZ1 A;  2NMB A;  1W1G A;  2BCJ A;  3F0W A;  2VSZ A;  1P6S A;  4HAU B;  5KQ4 A;  2D4Q A;  4WJ7 A;  1FGY A;  1M7R A;  2DYN A;  1KZG A;  2N23 A;  5DH9 B;  1BTK A;  2Y7B A;  4EMO A;  3X23 A;  2K2U A;  5JHG A;  2UZR A;  1J19 A;  1EAZ A;  1KZ7 A;  5C6R A;  3KY9 A;  5DIF B;  2LOX A;  5JLJ B;  5J3Q A;  1WJ1 A;  1W1H A;  1PLS A;  5GOW B;  2D9W A;  1LW3 A;  3N7C A;  4HAY B;  4K2P A;  2FJL A;  3PVU A;  1Y5O A;  4NY0 A;  4F7H A;  2L2I A;  5CLL B;  1XOD A;  1ZC4 B;  3VOQ A;  2GCJ A;  4CHJ A;  2YS5 A;  1DYN A;  1XCG A;  2AL6 A;  4NSW A;  2CAY A;  4A6K A;  3VIA A;  2V76 A;  1V61 A;  1WGU A;  4KAX B;  1GC7 A;  1SGH A;  2MWN B;  1FGZ A;  5CLQ B;  2KGX B;  2RUK B;  4HAT B;  3TO1 A;  5LOP B;  4HDO A;  2IYB A;  2D2Q A;  4A6H A;  3AU5 A;  4HDQ A;  2J0J A;  4F7U P;  1PFJ A; 
#chains in the Genus database with same CATH topology
 2K00 A;  2R0D A;  3ODW A;  3OAN A;  2OQB A;  1NU2 A;  2N0Y A;  4CYE A;  3SNH A;  3NWD A;  3PVW A;  1EGX A;  1MI1 A;  2VRW B;  2ZKM X;  4QJ5 B;  2D10 A;  4TYZ A;  2Z0O A;  2K2J A;  3NW8 A;  3OHM B;  2DX5 A;  4Z2M B;  2R09 A;  3HK0 A;  2LUL A;  2Z0P A;  4OT1 A;  4PQ0 A;  1DRO A;  2MKR A;  4MK0 A;  2YF0 A;  4Z2N A;  2VKI A;  3GYP A;  2DHI A;  3NWF A;  1W1D A;  2Y8F A;  1I2H A;  3SUZ A;  1U5D A;  3TVV A;  4QJ4 B;  1UNP A;  2ADZ A;  2DN6 A;  4C0A A;  2D11 A;  4OSN A;  3RCP A;  3QIJ A;  2ROV A;  2RRF A;  1FHO A;  2J0K A;  1FHW A;  4ZRJ A;  5EFX A;  1EF1 A;  2HE7 A;  2COC A;  2KUP A;  5JHH A;  2YT2 A;  2YT1 A;  2LOZ A;  2OTX A;  1FAO A;  1V89 A;  2CY4 A;  4XWX A;  2ROZ B;  2K8E A;  1U5G A;  5DHA B;  3O96 A;  4HB2 B;  4KHB B;  2I5F A;  1ZM0 A;  1UEF A;  1M7E A;  1EVH A;  3WA0 A;  5D27 A;  4ZRI A;  2DYQ A;  4HAZ B;  2H7E A;  4HB4 B;  3DXD A;  5IRS A;  2ZPY A;  4GMX B;  2XQN M;  4K81 A;  3U7D A;  1WGQ A;  4GN1 A;  4K17 A;  1BAK A;  1U5F A;  1NTY A;  3KRX A;  5HE2 A;  4ZRK A;  5FI1 A;  1QQG A;  2H7D A;  2D9X A;  1Q67 A;  3PEG A;  4YON A;  1TJ6 A;  4D6W A;  2X18 A;  3AJ4 A;  1K5G B;  1XKE A;  3P7Z A;  1BTN A;  3V5W A;  3UZT A;  1T77 A;  4DXA B;  2DKP A;  3ULB A;  5M4Y B;  5D3W A;  4GZU A;  1MK7 B;  5C79 A;  2EC1 A;  4QJ3 B;  2DLW A;  3T06 A;  3DCX A;  2KIE A;  2P0D A;  1V5P A;  2D9Y A;  2KCJ A;  5I2S A;  4IOY X;  2GCL A;  2DKQ A;  4A6F B;  4HAW B;  4DBB A;  1Z87 A;  3KSY A;  3F5R A;  1AQC A;  3AU4 A;  2GUM A;  2UVM A;  1TXD A;  4GOU A;  2ELA A;  4A6F A;  1ZSQ A;  2COA A;  1ISN A;  1OY2 A;  2W2X C;  3MDB C;  5LON B;  1UNR A;  1X1G A;  1U5E A;  3SO6 A;  1DDV A;  2P0F A;  4Y94 A;  1H4R A;  2Z4D A;  2L1C A;  4QXA B;  1XX0 A;  2Z14 A;  3B77 A;  4P7I A;  3HQC A;  1V88 A;  3DXE A;  1J0W A;  1ZYI A;  2Z13 A;  1PMS A;  4TKN A;  3TW1 A;  5D3X A;  1MIZ B;  2W2W A;  2EJ8 A;  1X11 A;  3NWA A;  4IAP A;  4L6E A;  2KIG A;  1IRS A;  2YS3 A;  4BBK A;  3BJI A;  2QKM A;  4B6H A;  3PP2 A;  5DI9 B;  3PZD A;  1U29 A;  1TQZ A;  5J3Y A;  3U8Z A;  2FJU B;  1OMW A;  1UNQ A;  4EKU A;  3BIN A;  3A58 A;  1V5U A;  3PG7 A;  1P5T A;  1V5M A;  2I1J A;  2GS0 A;  3SV1 A;  3NSU A;  3CIK A;  3ZVR A;  5HE1 A;  2AEH A;  1U2B A;  2DHJ A;  4DX8 A;  5KQ1 A;  2P0H A;  1MAI A;  5C5B B;  1GG3 A;  1MKE A;  3ZDT A;  2NZ8 B;  2EMS A;  1FOE A;  2RLO A;  2NBV A;  5FI0 A;  2YSZ A;  1KI1 B;  1QC6 A;  3ULC A;  2KUQ A;  1MPH A;  3KZ1 A;  1WJM A;  2DFK A;  5C5B A;  3TCA A;  1E5W A;  1LB1 A;  1I7A A;  2DX1 A;  4A5K A;  4MT7 A;  5LG4 B;  1H10 A;  1BWN A;  1FB8 A;  1K5D B;  5HE0 A;  2G35 A;  3FVC A;  2Y8G A;  4KHA A;  4DX9 0;  2DTC A;  4DIX A;  5D3V A;  1XR0 B;  5I2M A;  1OQN A;  1WG7 A;  4GMV A;  4K2O A;  2RGN B;  3PVL A;  2QKL A;  1DBH A;  2MDX A;  4HAX B;  1U27 A;  3A98 B;  4HSI A;  4D0N B;  4KHO A;  2LKO A;  4L1R A;  2DHK A;  3CXB B;  2RVB B;  3D8D A;  2LYD A;  3KRW A;  3HW2 B;  3A8P A;  3P6A A;  2IFS A;  5L81 A;  3QWM A;  2E2X A;  2CY5 A;  4WSF A;  5KCV A;  2RSG A;  2J59 M;  2YT0 A;  3ML4 A;  4PNK A;  2ELB A;  2MFQ A;  5C16 A;  2RNR B;  2JP2 A;  4HHV A;  1FHX A;  2J0M A;  3QBV B;  5J3T A;  3GYO A;  3SYX A;  2I5C A;  1NI2 A;  5D3Y A;  1DDM A;  4MY6 A;  2D9Z A;  4CSQ A;  2LG1 A;  2HTH B;  3ODO A;  3FEH A;  3FSS A;  1UPQ A;  1X05 A;  4GXB A;  2M38 A;  5HE3 A;  4F7G A;  1AWE A;  2COF A;  4H8S A;  4IFS A;  1ZC3 B;  1NTV A;  4HB3 B;  3G9W A;  4YL8 A;  3D8F A;  3D8E A;  1WI1 A;  3WYF B;  4KVG B;  2GJY A;  4WVF B;  3TFM A;  4GPT B;  1Y19 B;  2M14 A;  1P3R A;  1UPR A;  2W2X D;  2YRY A;  3M1I B;  1XD4 A;  3MPX A;  3LJU X;  1SHC A;  2Q13 A;  1B55 A;  2I1K A;  4GNK B;  5JP4 A;  1X86 A;  1WVH A;  4HB0 B;  1MIX A;  3DXC A;  1DDW A;  1GC6 A;  2DA0 A;  1RJ2 A;  3A8Q A;  3ODX A;  2YS1 A;  5DHF B;  2COD A;  2Z0Q A;  2UZS A;  1RRP B;  2CRF A;  2YVC A;  4HAV B;  4EJN A;  1N3H A;  3FM8 C;  3IVF A;  1X1F A;  2P8V A;  2EMT A;  1MK9 B;  4CHM A;  1ZVR A;  3PSC A;  2D9V A;  2PZ1 A;  2NMB A;  1W1G A;  3HSA A;  2BCJ A;  3F0W A;  2Z59 A;  3HIE A;  2VSZ A;  1P6S A;  4HAU B;  5KQ4 A;  2D4Q A;  4WJ7 A;  1FGY A;  1M7R A;  2DYN A;  1KZG A;  2N23 A;  5DH9 B;  1BTK A;  2Y7B A;  4EMO A;  3X23 A;  2K2U A;  5JHG A;  2UZR A;  1J19 A;  1EAZ A;  1KZ7 A;  5C6R A;  3KY9 A;  5DIF B;  2LOX A;  5JLJ B;  5J3Q A;  1WJ1 A;  1W1H A;  1PLS A;  5GOW B;  2D9W A;  1LW3 A;  3N7C A;  4HAY B;  4K2P A;  4KHB A;  2FJL A;  3PVU A;  1Y5O A;  4NY0 A;  4F7H A;  2L2I A;  5CLL B;  1XOD A;  1ZC4 B;  3VOQ A;  2GCJ A;  4CHJ A;  2YS5 A;  1DYN A;  2K49 A;  1XCG A;  2AL6 A;  4NSW A;  2CAY A;  4A6K A;  3VIA A;  2V76 A;  3U12 A;  1V61 A;  1WGU A;  4KAX B;  2R2Y A;  1GC7 A;  1SGH A;  2MWN B;  1FGZ A;  5CLQ B;  2KGX B;  2KR0 A;  2RUK B;  4HAT B;  3TO1 A;  5LOP B;  4HDO A;  2IYB A;  2D2Q A;  4A6H A;  3AU5 A;  4HDQ A;  2J0J A;  4F7U P;  1PFJ A; 
#chains in the Genus database with same CATH homology
 2K00 A;  2R0D A;  3ODW A;  3OAN A;  2OQB A;  1NU2 A;  2N0Y A;  4CYE A;  3SNH A;  3PVW A;  1EGX A;  2VRW B;  2D10 A;  4TYZ A;  2Z0O A;  2K2J A;  2DX5 A;  4Z2M B;  2R09 A;  3HK0 A;  2LUL A;  2Z0P A;  4PQ0 A;  1DRO A;  2MKR A;  4MK0 A;  2YF0 A;  4Z2N A;  2VKI A;  3GYP A;  2DHI A;  1W1D A;  2Y8F A;  1I2H A;  3SUZ A;  1U5D A;  3TVV A;  1UNP A;  2ADZ A;  2DN6 A;  4C0A A;  2D11 A;  3RCP A;  3QIJ A;  2ROV A;  1FHO A;  2J0K A;  1FHW A;  4ZRJ A;  5EFX A;  1EF1 A;  2HE7 A;  2COC A;  2KUP A;  5JHH A;  2YT1 A;  2LOZ A;  2OTX A;  1FAO A;  1V89 A;  2CY4 A;  4XWX A;  2ROZ B;  1U5G A;  5DHA B;  3O96 A;  4HB2 B;  4KHB B;  2I5F A;  1ZM0 A;  1UEF A;  1M7E A;  1EVH A;  3WA0 A;  5D27 A;  4ZRI A;  2DYQ A;  4HAZ B;  2H7E A;  4HB4 B;  3DXD A;  2ZPY A;  4GMX B;  2XQN M;  4K81 A;  3U7D A;  1WGQ A;  4GN1 A;  4K17 A;  1BAK A;  1U5F A;  1NTY A;  3KRX A;  5HE2 A;  4ZRK A;  5FI1 A;  1QQG A;  2H7D A;  2D9X A;  3PEG A;  1Q67 A;  4YON A;  1TJ6 A;  2X18 A;  3AJ4 A;  1K5G B;  1XKE A;  3P7Z A;  1BTN A;  3V5W A;  3UZT A;  4DXA B;  2DKP A;  3ULB A;  5D3W A;  4GZU A;  1MK7 B;  5C79 A;  2EC1 A;  2DLW A;  3T06 A;  2P0D A;  1V5P A;  2D9Y A;  2KCJ A;  4IOY X;  2GCL A;  2DKQ A;  4A6F B;  4HAW B;  4DBB A;  1Z87 A;  3KSY A;  3F5R A;  1AQC A;  3AU4 A;  2UVM A;  1TXD A;  2ELA A;  4A6F A;  1ZSQ A;  2COA A;  1ISN A;  1OY2 A;  2W2X C;  3MDB C;  5LON B;  1UNR A;  1X1G A;  1U5E A;  3SO6 A;  1DDV A;  2P0F A;  4Y94 A;  1H4R A;  2L1C A;  1XX0 A;  4P7I A;  3HQC A;  1V88 A;  3DXE A;  1J0W A;  1PMS A;  4TKN A;  3TW1 A;  5D3X A;  1MIZ B;  2W2W A;  2EJ8 A;  1X11 A;  4IAP A;  4L6E A;  1IRS A;  2YS3 A;  4BBK A;  3BJI A;  2QKM A;  4B6H A;  3PP2 A;  5DI9 B;  3PZD A;  1U29 A;  1TQZ A;  5J3Y A;  3U8Z A;  1OMW A;  1UNQ A;  4EKU A;  3BIN A;  3PG7 A;  1V5U A;  1P5T A;  1V5M A;  2I1J A;  2GS0 A;  3SV1 A;  3NSU A;  3CIK A;  3ZVR A;  5HE1 A;  2AEH A;  1U2B A;  2DHJ A;  4DX8 A;  5KQ1 A;  2P0H A;  1MAI A;  5C5B B;  1GG3 A;  1MKE A;  3ZDT A;  2NZ8 B;  2EMS A;  1FOE A;  2RLO A;  5FI0 A;  2YSZ A;  1KI1 B;  1QC6 A;  3ULC A;  1MPH A;  3KZ1 A;  1WJM A;  2DFK A;  5C5B A;  3TCA A;  1E5W A;  1LB1 A;  1I7A A;  2DX1 A;  4A5K A;  4MT7 A;  1H10 A;  1BWN A;  1FB8 A;  1K5D B;  5HE0 A;  2G35 A;  2Y8G A;  4KHA A;  4DX9 0;  2DTC A;  5D3V A;  1XR0 B;  1OQN A;  1WG7 A;  4GMV A;  4K2O A;  2RGN B;  3PVL A;  2QKL A;  1DBH A;  2MDX A;  4HAX B;  1U27 A;  3A98 B;  4D0N B;  4KHO A;  2LKO A;  2DHK A;  3CXB B;  2RVB B;  3D8D A;  2LYD A;  3KRW A;  3HW2 B;  3A8P A;  3P6A A;  2IFS A;  5L81 A;  3QWM A;  2E2X A;  2CY5 A;  4WSF A;  5KCV A;  2RSG A;  2J59 M;  2YT0 A;  3ML4 A;  4PNK A;  2ELB A;  2MFQ A;  5C16 A;  2RNR B;  2JP2 A;  4HHV A;  1FHX A;  2J0M A;  3QBV B;  5J3T A;  3GYO A;  3SYX A;  2I5C A;  1NI2 A;  5D3Y A;  1DDM A;  4MY6 A;  2D9Z A;  2LG1 A;  2HTH B;  3ODO A;  3FEH A;  3FSS A;  1UPQ A;  1X05 A;  4GXB A;  2M38 A;  5HE3 A;  4F7G A;  1AWE A;  2COF A;  4H8S A;  4IFS A;  1ZC3 B;  1NTV A;  4HB3 B;  3G9W A;  4YL8 A;  3D8F A;  3D8E A;  1WI1 A;  3WYF B;  4KVG B;  2GJY A;  4WVF B;  3TFM A;  4GPT B;  1Y19 B;  2M14 A;  1P3R A;  1UPR A;  2W2X D;  2YRY A;  3M1I B;  1XD4 A;  3MPX A;  3LJU X;  1SHC A;  2Q13 A;  1B55 A;  2I1K A;  5JP4 A;  1X86 A;  1WVH A;  4HB0 B;  1MIX A;  3DXC A;  1DDW A;  1GC6 A;  2DA0 A;  1RJ2 A;  3A8Q A;  3ODX A;  2YS1 A;  5DHF B;  2COD A;  2Z0Q A;  2UZS A;  1RRP B;  2CRF A;  2YVC A;  4HAV B;  4EJN A;  1N3H A;  3FM8 C;  3IVF A;  1X1F A;  2P8V A;  2EMT A;  1MK9 B;  4CHM A;  1ZVR A;  3PSC A;  2D9V A;  2PZ1 A;  2NMB A;  1W1G A;  2BCJ A;  3F0W A;  2VSZ A;  1P6S A;  4HAU B;  5KQ4 A;  2D4Q A;  4WJ7 A;  1FGY A;  1M7R A;  2DYN A;  1KZG A;  2N23 A;  5DH9 B;  1BTK A;  2Y7B A;  4EMO A;  3X23 A;  2K2U A;  5JHG A;  2UZR A;  1J19 A;  1EAZ A;  1KZ7 A;  5C6R A;  3KY9 A;  5DIF B;  2LOX A;  5JLJ B;  5J3Q A;  1WJ1 A;  1W1H A;  1PLS A;  5GOW B;  2D9W A;  1LW3 A;  3N7C A;  4HAY B;  4K2P A;  2FJL A;  3PVU A;  1Y5O A;  4NY0 A;  4F7H A;  2L2I A;  5CLL B;  1XOD A;  1ZC4 B;  3VOQ A;  2GCJ A;  4CHJ A;  2YS5 A;  1DYN A;  1XCG A;  2AL6 A;  4NSW A;  2CAY A;  4A6K A;  3VIA A;  2V76 A;  1V61 A;  1WGU A;  4KAX B;  1GC7 A;  1SGH A;  2MWN B;  1FGZ A;  5CLQ B;  2KGX B;  2RUK B;  4HAT B;  3TO1 A;  5LOP B;  4HDO A;  2IYB A;  2D2Q A;  4A6H A;  3AU5 A;  4HDQ A;  2J0J A;  4F7U P;  1PFJ A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4WJ7A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN