4Y94 | Genus

Total Genus 28

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	28
sequence length	167
structure length	158
Chain Sequence	ATVILESIFLKRSSPLNFKKRLFLLTVQKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIPEESSETEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQIL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__4521592677592126__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__4521592677592126__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/4Y94/A/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__4521592677592126__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"4521592677592126","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/4Y94/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__4521592677592126__ ready

script 1 started

platformSpeed = 8

Viewer cachePut cache://localLOAD_/file/5d00d4907611c2024eb7facc/pdb.gz

Viewer cachePut https://genus.fuw.edu.pl/file/5d00d4907611c2024eb7facc/pdb.gz

FileManager.getAtomSetCollectionFromFile(/file/5d00d4907611c2024eb7facc/pdb.gz)

loadScript /static/js/j2s/core/corezip.z.js

The Resolver thinks Pdb

loadScript /static/js/j2s/core/corebio.z.js

Time for openFile(/file/5d00d4907611c2024eb7facc/pdb.gz): 1298 ms

reading 158 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

158 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 20 ms

Adding embedded #jmolscript: select ({0:157});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Bos taurus
publication title	Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate. pubmed doi rcsb
molecule keywords	Non-specific protein-tyrosine kinase
total genus	28
structure length	158
sequence length	167
chains with identical sequence	B, C, D
ec nomenclature	ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date	2015-02-16

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00169	PH	PH domain
A	PF00779	BTK	BTK motif

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.30.29.30	Mainly Beta	Roll	PH-domain like	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	4y94A00

2DA0A 4HDQA 2COFA 4TYZA 5JLJB 2DKPA 2H7EA 2P8VA 1DBHA 2KGXB 4HAWB 1UNQA 2DFKA 1DDWA 3IVFA 4F7HA 1FGYA 3GYPA 4CYEA 3PVUA 4CHJA 4BBKA 4HB0B 3SUZA 3QBVB 4WVFB 1V88A 2RLOA 4EMOA 3QIJA 2MWNB 4NY0A 4DX8A 2MKRA 3HK0A 4NSWA 3TW1A 2K2UA 3F5RA 5J3QA 1XR0B 1V61A 4IOYX 2HTHB 1WI1A 4ZRJA 4B6HA 2W2WA 2D10A 5C16A 4K17A 1U5DA 3DXDA 3M1IB 5J3TA 2YS3A 2ADZA 1XD4A 2PZ1A 3FM8C 1XX0A 2IYBA 1BAKA 1K5DB 1M7EA 4HB3B 1V5UA 3PVLA 1QQGA 3F0WA 4TKNA 4DXAB 1ZVRA 2RVBB 2FJLA 2ELBA 5KCVA 3KSYA 1OY2A 1V89A 1ISNA 4KHOA 2EJ8A 1KZ7A 1MAIA 2IFSA 4DBBA 2LULA 1V5PA 1EVHA 5D27A 2OTXA 4HB2B 2DX5A 1OQNA 1WGQA 1X86A 4H8SA 3A8PA 3MPXA 4F7GA 3AJ4A 1MK7B 2HE7A 1FHXA 3TVVA 2KUPA 2ROZB 4KHAA 2J0JA 3PVWA 5HE3A 3O96A 1DROA 2P0DA 4HAYB 2QKMA 4MK0A 2KCJA 2XQNM 2J59M 2CY4A 1UNRA 1IRSA 1OMWA 2UZRA 5C79A 1Z87A 3ODOA 1J19A 1MKEA 3PSCA 4HATB 2L2IA 3P6AA 5JP4A 1U5FA 1WVHA 4PQ0A 3T06A 2LOZA 4KAXB 2LOXA 3DXEA 1FOEA 3MDBC 5DH9B 3ODWA 1GG3A 4WSFA 5C5BB 1U27A 3NSUA 4A6KA 2R0DA 1E5WA 4HAVB 2RNRB 4EKUA 3WA0A 3ZVRA 5C6RA 2P0HA 4Y94A 2DN6A 2V76A 1N3HA 1QC6A 3ULBA 3KZ1A 3VIAA 2YF0A 4HAZB 1XCGA 2Y7BA 4D0NB 1NTVA 1TJ6A 5GOWB 2N0YA 5EFXA 1GC7A 1BWNA 2Y8GA 2K2JA 4YL8A 2R09A 3ML4A 4MT7A 5HE0A 2E2XA 5D3XA 2DHJA 1EF1A 4IAPA 2CODA 1M7RA 2YS5A 3PP2A 2D9XA 1EAZA 3SV1A 3OANA 2D4QA 1TXDA 2CRFA 1RJ2A 1PMSA 1FB8A 2OQBA 1DYNA 2GCJA 5FI1A 4K81A 1H10A 1EGXA 2ROVA 1ZC4B 2DHIA 3A98B 1UPRA 2AL6A 1TQZA 4Z2NA 1MIZB 3KRWA 2LKOA 5D3VA 4HB4B 1MIXA 1FHWA 3D8FA 1V5MA 4DX90 3TFMA 2I5FA 5KQ4A 3D8EA 4KHBB 4EJNA 4ZRKA 1J0WA 4GXBA 3AU4A 3DXCA 2DTCA 4MY6A 2D9VA 2D9YA 1BTNA 2N23A 2RUKB 2COCA 1GC6A 2ELAA 4HDOA 4PNKA 5CLQB 2YT1A 2H7DA 1KI1B 4P7IA 4CHMA 1MPHA 2DLWA 2ZPYA 1DDMA 3FEHA 5DI9B 2D9WA 1WGUA 3CXBB 1ZC3B 1NU2A 1FGZA 5JHHA 3U7DA 1PFJA 4GZUA 2L1CA 3D8DA 3PZDA 1LW3A 3P7ZA 2EC1A 2YS1A 1LB1A 1W1HA 2MFQA 1I2HA 3BJIA 1KZGA 3ODXA 4ZRIA 2UZSA 5CLLB 4IFSA 5DIFB 2Y8FA 2I5CA 3TCAA 4XWXA 3AU5A 1UNPA 2Q13A 1H4RA 2M38A 1SHCA 2K00A 2BCJA 5DHAB 2I1KA 1B55A 4A6FB 4YONA 2COAA 3G9WA 5J3YA 2DYQA 3SYXA 3RCPA 2JP2A 2DYNA 2YVCA 2P0FA 4L6EA 2UVMA 2DKQA 4K2PA 3FSSA 1X1FA 2YT0A 3HQCA 1W1DA 1BTKA 1MK9B 1XKEA 1FAOA 2GJYA 1W1GA 5D3YA 1DDVA 2D11A 2DX1A 2M14A 3A8QA 4F7UP 3VOQA 4GN1A 1P5TA 2EMTA 1P3RA 3KRXA 2D2QA 3N7CA 1WJ1A 3PG7A 2RSGA 1ZM0A 2NZ8B 4KVGB 2Z0OA 5FI0A 2QKLA 5DHFB 2AEHA 1RRPB 2D9ZA 5C5BA 2VKIA 1FHOA 2EMSA 1AQCA 1NTYA 3ULCA 2RGNB 1Y19B 3HW2B 2I1JA 2G35A 3X23A 2Z0QA 4C0AA 4A6FA 3BINA 5HE1A 2LG1A 4HAUB 1U5GA 1I7AA 2NMBA 4Z2MB 5LONB 2VRWB 3SNHA 4A6HA 3SO6A 1AWEA 2GCLA 2DHKA 3KY9A 1U2BA 3QWMA 1Q67A 1UPQA 1X11A 1XODA 1SGHA 3ZDTA 4K2OA 5JHGA 1U29A 2J0KA 4GMXB 3TO1A 5KQ1A 1K5GB 3GYOA 3U8ZA 4A5KA 3WYFB 1WJMA 2CAYA 3UZTA 3LJUX 5HE2A 3V5WA 2CY5A 2J0MA 4GPTB 2LYDA 1UEFA 4GMVA 4HHVA 3PEGA 1ZSQA 1NI2A 1P6SA 1PLSA 4WJ7A 2VSZA 1Y5OA 5LOPB 5D3WA 1U5EA 1X05A 2GS0A 2MDXA 1X1GA 2YRYA 4HAXB 2X18A 3CIKA 5L81A 2W2XD 2YSZA 1WG7A 2W2XC 2Z0PA
chains in the Genus database with same CATH superfamily

1ZYIA 2DA0A 4HDQA 2COFA 4TYZA 5JLJB 2DKPA 2H7EA 2P8VA 1DBHA 2KGXB 4HAWB 1UNQA 2DFKA 1DDWA 3IVFA 4F7HA 1FGYA 3GYPA 4CYEA 3PVUA 4CHJA 4BBKA 4HB0B 3SUZA 3QBVB 4WVFB 4HSIA 1V88A 2RLOA 4EMOA 3QIJA 2MWNB 4NY0A 2K49A 4DX8A 4QJ3B 2MKRA 3HK0A 4NSWA 3TW1A 4KHBA 2K2UA 3F5RA 5J3QA 1XR0B 1V61A 4IOYX 2HTHB 1WI1A 4ZRJA 4B6HA 2W2WA 2D10A 2Z14A 5C16A 4K17A 1U5DA 3DXDA 3M1IB 5J3TA 2YS3A 2ADZA 1XD4A 2PZ1A 3FM8C 1XX0A 2IYBA 1BAKA 1K5DB 1M7EA 4HB3B 1V5UA 3PVLA 1QQGA 3F0WA 4TKNA 4DXAB 1ZVRA 2RVBB 2FJLA 2ELBA 5KCVA 3KSYA 1OY2A 1V89A 1ISNA 3NWAA 4KHOA 2EJ8A 1KZ7A 1MAIA 2IFSA 4DBBA 2LULA 1V5PA 3NWFA 1EVHA 5D27A 2OTXA 4HB2B 3OHMB 2DX5A 1OQNA 1WGQA 1X86A 4H8SA 3A8PA 3MPXA 4F7GA 3AJ4A 2KIGA 1MK7B 2HE7A 1FHXA 3TVVA 2KUPA 2ROZB 4KHAA 2J0JA 1T77A 3PVWA 5HE3A 3O96A 1DROA 2P0DA 4HAYB 2QKMA 4MK0A 2KCJA 2XQNM 2J59M 2CY4A 1UNRA 1IRSA 5I2SA 1OMWA 2UZRA 5C79A 1Z87A 3ODOA 1J19A 1MKEA 3PSCA 4HATB 2L2IA 3A58A 5I2MA 3P6AA 5JP4A 1U5FA 1WVHA 4PQ0A 3T06A 2LOZA 4KAXB 2LOXA 3DXEA 1FOEA 3MDBC 5DH9B 3ODWA 1GG3A 4WSFA 5C5BB 1U27A 3NSUA 4A6KA 2R0DA 2Z59A 1E5WA 4HAVB 2RNRB 4EKUA 3WA0A 3ZVRA 5C6RA 2P0HA 4Y94A 2DN6A 2V76A 1N3HA 1QC6A 5M4YB 3ULBA 3KZ1A 3VIAA 2K8EA 2YF0A 4HAZB 1XCGA 2Y7BA 4D0NB 1NTVA 1TJ6A 5GOWB 2N0YA 5EFXA 1GC7A 1BWNA 2Y8GA 2K2JA 4YL8A 2R09A 3ML4A 4MT7A 5HE0A 2E2XA 5D3XA 4QJ5B 2DHJA 1EF1A 4IAPA 2CODA 3NW8A 1M7RA 2YS5A 3U12A 4QJ4B 3HSAA 3PP2A 4QXAB 2D9XA 1EAZA 3SV1A 2D4QA 3OANA 1TXDA 2CRFA 1RJ2A 1PMSA 1FB8A 2OQBA 1DYNA 2GCJA 5FI1A 4K81A 1H10A 4OSNA 4DIXA 1EGXA 2NBVA 2ROVA 1ZC4B 2DHIA 3A98B 1UPRA 2AL6A 1TQZA 3NWDA 4Z2NA 1MIZB 3KRWA 2LKOA 5D3VA 4HB4B 1MIXA 1FHWA 3D8FA 1V5MA 2Z13A 4DX90 3TFMA 2I5FA 5KQ4A 3D8EA 4KHBB 4EJNA 4ZRKA 1J0WA 4GXBA 3AU4A 3DXCA 2DTCA 4MY6A 2R2YA 2D9VA 2D9YA 1BTNA 2N23A 2RUKB 2COCA 1GC6A 2ELAA 4HDOA 4PNKA 5CLQB 2YT1A 2H7DA 1KI1B 4P7IA 4CHMA 1MI1A 1MPHA 2DLWA 5IRSA 2ZPYA 1DDMA 3FEHA 5DI9B 2D9WA 1WGUA 3CXBB 3B77A 1ZC3B 1NU2A 1FGZA 4CSQA 5JHHA 3U7DA 1PFJA 4GZUA 2L1CA 3D8DA 3PZDA 1LW3A 2EC1A 2YS1A 3P7ZA 1LB1A 1W1HA 3HIEA 2MFQA 1I2HA 3BJIA 2FJUB 1KZGA 3ODXA 4ZRIA 2UZSA 5CLLB 4IFSA 5DIFB 2Y8FA 2I5CA 3TCAA 4XWXA 3AU5A 1UNPA 2Q13A 1H4RA 2M38A 1SHCA 4OT1A 2K00A 2BCJA 5DHAB 2I1KA 1B55A 4A6FB 4YONA 2COAA 3G9WA 5J3YA 2DYQA 3SYXA 2RRFA 3RCPA 2JP2A 2DYNA 2YVCA 2P0FA 4L6EA 2UVMA 2DKQA 2KIEA 4K2PA 3FSSA 1X1FA 2YT0A 3HQCA 1W1DA 1BTKA 1MK9B 1XKEA 1FAOA 2GJYA 1W1GA 5D3YA 1DDVA 2D11A 2DX1A 2M14A 3A8QA 4F7UP 3VOQA 4GN1A 1P5TA 2EMTA 2ZKMX 1P3RA 3KRXA 2D2QA 3N7CA 5LG4B 4D6WA 1WJ1A 3PG7A 2RSGA 1ZM0A 2NZ8B 4KVGB 2Z0OA 5FI0A 2QKLA 5DHFB 2AEHA 1RRPB 2D9ZA 5C5BA 2VKIA 1FHOA 2EMSA 1AQCA 1NTYA 2KR0A 3ULCA 2RGNB 2Z4DA 1Y19B 3HW2B 2I1JA 2G35A 3X23A 2Z0QA 4C0AA 4A6FA 3BINA 5HE1A 2GUMA 2LG1A 4HAUB 1U5GA 1I7AA 2NMBA 4Z2MB 2YT2A 5LONB 2VRWB 3SNHA 4A6HA 3SO6A 1AWEA 2GCLA 2DHKA 3KY9A 1U2BA 3QWMA 1Q67A 1UPQA 1X11A 1XODA 1SGHA 3ZDTA 2KUQA 4K2OA 5JHGA 1U29A 2J0KA 4GMXB 3TO1A 5KQ1A 1K5GB 3GYOA 3U8ZA 4A5KA 3WYFB 1WJMA 2CAYA 3UZTA 3LJUX 5HE2A 3V5WA 2CY5A 3FVCA 2J0MA 4GPTB 2LYDA 1UEFA 4GMVA 4HHVA 3PEGA 4GOUA 1ZSQA 1NI2A 1P6SA 1PLSA 4WJ7A 2VSZA 1Y5OA 5LOPB 5D3WA 1U5EA 1X05A 2GS0A 2MDXA 1X1GA 2YRYA 4HAXB 3DCXA 2X18A 3CIKA 4GNKB 5L81A 2W2XD 2YSZA 4L1RA 1WG7A 2W2XC 2Z0PA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2DA0 A;  4HDQ A;  2COF A;  4TYZ A;  5JLJ B;  2DKP A;  2H7E A;  2P8V A;  1DBH A;  2KGX B;  4HAW B;  1UNQ A;  2DFK A;  1DDW A;  3IVF A;  4F7H A;  1FGY A;  3GYP A;  4CYE A;  3PVU A;  4CHJ A;  4BBK A;  4HB0 B;  3SUZ A;  3QBV B;  4WVF B;  1V88 A;  2RLO A;  4EMO A;  3QIJ A;  2MWN B;  4NY0 A;  4DX8 A;  2MKR A;  3HK0 A;  4NSW A;  3TW1 A;  2K2U A;  3F5R A;  5J3Q A;  1XR0 B;  1V61 A;  4IOY X;  2HTH B;  1WI1 A;  4ZRJ A;  4B6H A;  2W2W A;  2D10 A;  5C16 A;  4K17 A;  1U5D A;  3DXD A;  3M1I B;  5J3T A;  2YS3 A;  2ADZ A;  1XD4 A;  2PZ1 A;  3FM8 C;  1XX0 A;  2IYB A;  1BAK A;  1K5D B;  1M7E A;  4HB3 B;  1V5U A;  3PVL A;  1QQG A;  3F0W A;  4TKN A;  4DXA B;  1ZVR A;  2RVB B;  2FJL A;  2ELB A;  5KCV A;  3KSY A;  1OY2 A;  1V89 A;  1ISN A;  4KHO A;  2EJ8 A;  1KZ7 A;  1MAI A;  2IFS A;  4DBB A;  2LUL A;  1V5P A;  1EVH A;  5D27 A;  2OTX A;  4HB2 B;  2DX5 A;  1OQN A;  1WGQ A;  1X86 A;  4H8S A;  3A8P A;  3MPX A;  4F7G A;  3AJ4 A;  1MK7 B;  2HE7 A;  1FHX A;  3TVV A;  2KUP A;  2ROZ B;  4KHA A;  2J0J A;  3PVW A;  5HE3 A;  3O96 A;  1DRO A;  2P0D A;  4HAY B;  2QKM A;  4MK0 A;  2KCJ A;  2XQN M;  2J59 M;  2CY4 A;  1UNR A;  1IRS A;  1OMW A;  2UZR A;  5C79 A;  1Z87 A;  3ODO A;  1J19 A;  1MKE A;  3PSC A;  4HAT B;  2L2I A;  3P6A A;  5JP4 A;  1U5F A;  1WVH A;  4PQ0 A;  3T06 A;  2LOZ A;  4KAX B;  2LOX A;  3DXE A;  1FOE A;  3MDB C;  5DH9 B;  3ODW A;  1GG3 A;  4WSF A;  5C5B B;  1U27 A;  3NSU A;  4A6K A;  2R0D A;  1E5W A;  4HAV B;  2RNR B;  4EKU A;  3WA0 A;  3ZVR A;  5C6R A;  2P0H A;  4Y94 A;  2DN6 A;  2V76 A;  1N3H A;  1QC6 A;  3ULB A;  3KZ1 A;  3VIA A;  2YF0 A;  4HAZ B;  1XCG A;  2Y7B A;  4D0N B;  1NTV A;  1TJ6 A;  5GOW B;  2N0Y A;  5EFX A;  1GC7 A;  1BWN A;  2Y8G A;  2K2J A;  4YL8 A;  2R09 A;  3ML4 A;  4MT7 A;  5HE0 A;  2E2X A;  5D3X A;  2DHJ A;  1EF1 A;  4IAP A;  2COD A;  1M7R A;  2YS5 A;  3PP2 A;  2D9X A;  1EAZ A;  3SV1 A;  3OAN A;  2D4Q A;  1TXD A;  2CRF A;  1RJ2 A;  1PMS A;  1FB8 A;  2OQB A;  1DYN A;  2GCJ A;  5FI1 A;  4K81 A;  1H10 A;  1EGX A;  2ROV A;  1ZC4 B;  2DHI A;  3A98 B;  1UPR A;  2AL6 A;  1TQZ A;  4Z2N A;  1MIZ B;  3KRW A;  2LKO A;  5D3V A;  4HB4 B;  1MIX A;  1FHW A;  3D8F A;  1V5M A;  4DX9 0;  3TFM A;  2I5F A;  5KQ4 A;  3D8E A;  4KHB B;  4EJN A;  4ZRK A;  1J0W A;  4GXB A;  3AU4 A;  3DXC A;  2DTC A;  4MY6 A;  2D9V A;  2D9Y A;  1BTN A;  2N23 A;  2RUK B;  2COC A;  1GC6 A;  2ELA A;  4HDO A;  4PNK A;  5CLQ B;  2YT1 A;  2H7D A;  1KI1 B;  4P7I A;  4CHM A;  1MPH A;  2DLW A;  2ZPY A;  1DDM A;  3FEH A;  5DI9 B;  2D9W A;  1WGU A;  3CXB B;  1ZC3 B;  1NU2 A;  1FGZ A;  5JHH A;  3U7D A;  1PFJ A;  4GZU A;  2L1C A;  3D8D A;  3PZD A;  1LW3 A;  3P7Z A;  2EC1 A;  2YS1 A;  1LB1 A;  1W1H A;  2MFQ A;  1I2H A;  3BJI A;  1KZG A;  3ODX A;  4ZRI A;  2UZS A;  5CLL B;  4IFS A;  5DIF B;  2Y8F A;  2I5C A;  3TCA A;  4XWX A;  3AU5 A;  1UNP A;  2Q13 A;  1H4R A;  2M38 A;  1SHC A;  2K00 A;  2BCJ A;  5DHA B;  2I1K A;  1B55 A;  4A6F B;  4YON A;  2COA A;  3G9W A;  5J3Y A;  2DYQ A;  3SYX A;  3RCP A;  2JP2 A;  2DYN A;  2YVC A;  2P0F A;  4L6E A;  2UVM A;  2DKQ A;  4K2P A;  3FSS A;  1X1F A;  2YT0 A;  3HQC A;  1W1D A;  1BTK A;  1MK9 B;  1XKE A;  1FAO A;  2GJY A;  1W1G A;  5D3Y A;  1DDV A;  2D11 A;  2DX1 A;  2M14 A;  3A8Q A;  4F7U P;  3VOQ A;  4GN1 A;  1P5T A;  2EMT A;  1P3R A;  3KRX A;  2D2Q A;  3N7C A;  1WJ1 A;  3PG7 A;  2RSG A;  1ZM0 A;  2NZ8 B;  4KVG B;  2Z0O A;  5FI0 A;  2QKL A;  5DHF B;  2AEH A;  1RRP B;  2D9Z A;  5C5B A;  2VKI A;  1FHO A;  2EMS A;  1AQC A;  1NTY A;  3ULC A;  2RGN B;  1Y19 B;  3HW2 B;  2I1J A;  2G35 A;  3X23 A;  2Z0Q A;  4C0A A;  4A6F A;  3BIN A;  5HE1 A;  2LG1 A;  4HAU B;  1U5G A;  1I7A A;  2NMB A;  4Z2M B;  5LON B;  2VRW B;  3SNH A;  4A6H A;  3SO6 A;  1AWE A;  2GCL A;  2DHK A;  3KY9 A;  1U2B A;  3QWM A;  1Q67 A;  1UPQ A;  1X11 A;  1XOD A;  1SGH A;  3ZDT A;  4K2O A;  5JHG A;  1U29 A;  2J0K A;  4GMX B;  3TO1 A;  5KQ1 A;  1K5G B;  3GYO A;  3U8Z A;  4A5K A;  3WYF B;  1WJM A;  2CAY A;  3UZT A;  3LJU X;  5HE2 A;  3V5W A;  2CY5 A;  2J0M A;  4GPT B;  2LYD A;  1UEF A;  4GMV A;  4HHV A;  3PEG A;  1ZSQ A;  1NI2 A;  1P6S A;  1PLS A;  4WJ7 A;  2VSZ A;  1Y5O A;  5LOP B;  5D3W A;  1U5E A;  1X05 A;  2GS0 A;  2MDX A;  1X1G A;  2YRY A;  4HAX B;  2X18 A;  3CIK A;  5L81 A;  2W2X D;  2YSZ A;  1WG7 A;  2W2X C;  2Z0P A; 
#chains in the Genus database with same CATH topology
 1ZYI A;  2DA0 A;  4HDQ A;  2COF A;  4TYZ A;  5JLJ B;  2DKP A;  2H7E A;  2P8V A;  1DBH A;  2KGX B;  4HAW B;  1UNQ A;  2DFK A;  1DDW A;  3IVF A;  4F7H A;  1FGY A;  3GYP A;  4CYE A;  3PVU A;  4CHJ A;  4BBK A;  4HB0 B;  3SUZ A;  3QBV B;  4WVF B;  4HSI A;  1V88 A;  2RLO A;  4EMO A;  3QIJ A;  2MWN B;  4NY0 A;  2K49 A;  4DX8 A;  4QJ3 B;  2MKR A;  3HK0 A;  4NSW A;  3TW1 A;  4KHB A;  2K2U A;  3F5R A;  5J3Q A;  1XR0 B;  1V61 A;  4IOY X;  2HTH B;  1WI1 A;  4ZRJ A;  4B6H A;  2W2W A;  2D10 A;  2Z14 A;  5C16 A;  4K17 A;  1U5D A;  3DXD A;  3M1I B;  5J3T A;  2YS3 A;  2ADZ A;  1XD4 A;  2PZ1 A;  3FM8 C;  1XX0 A;  2IYB A;  1BAK A;  1K5D B;  1M7E A;  4HB3 B;  1V5U A;  3PVL A;  1QQG A;  3F0W A;  4TKN A;  4DXA B;  1ZVR A;  2RVB B;  2FJL A;  2ELB A;  5KCV A;  3KSY A;  1OY2 A;  1V89 A;  1ISN A;  3NWA A;  4KHO A;  2EJ8 A;  1KZ7 A;  1MAI A;  2IFS A;  4DBB A;  2LUL A;  1V5P A;  3NWF A;  1EVH A;  5D27 A;  2OTX A;  4HB2 B;  3OHM B;  2DX5 A;  1OQN A;  1WGQ A;  1X86 A;  4H8S A;  3A8P A;  3MPX A;  4F7G A;  3AJ4 A;  2KIG A;  1MK7 B;  2HE7 A;  1FHX A;  3TVV A;  2KUP A;  2ROZ B;  4KHA A;  2J0J A;  1T77 A;  3PVW A;  5HE3 A;  3O96 A;  1DRO A;  2P0D A;  4HAY B;  2QKM A;  4MK0 A;  2KCJ A;  2XQN M;  2J59 M;  2CY4 A;  1UNR A;  1IRS A;  5I2S A;  1OMW A;  2UZR A;  5C79 A;  1Z87 A;  3ODO A;  1J19 A;  1MKE A;  3PSC A;  4HAT B;  2L2I A;  3A58 A;  5I2M A;  3P6A A;  5JP4 A;  1U5F A;  1WVH A;  4PQ0 A;  3T06 A;  2LOZ A;  4KAX B;  2LOX A;  3DXE A;  1FOE A;  3MDB C;  5DH9 B;  3ODW A;  1GG3 A;  4WSF A;  5C5B B;  1U27 A;  3NSU A;  4A6K A;  2R0D A;  2Z59 A;  1E5W A;  4HAV B;  2RNR B;  4EKU A;  3WA0 A;  3ZVR A;  5C6R A;  2P0H A;  4Y94 A;  2DN6 A;  2V76 A;  1N3H A;  1QC6 A;  5M4Y B;  3ULB A;  3KZ1 A;  3VIA A;  2K8E A;  2YF0 A;  4HAZ B;  1XCG A;  2Y7B A;  4D0N B;  1NTV A;  1TJ6 A;  5GOW B;  2N0Y A;  5EFX A;  1GC7 A;  1BWN A;  2Y8G A;  2K2J A;  4YL8 A;  2R09 A;  3ML4 A;  4MT7 A;  5HE0 A;  2E2X A;  5D3X A;  4QJ5 B;  2DHJ A;  1EF1 A;  4IAP A;  2COD A;  3NW8 A;  1M7R A;  2YS5 A;  3U12 A;  4QJ4 B;  3HSA A;  3PP2 A;  4QXA B;  2D9X A;  1EAZ A;  3SV1 A;  2D4Q A;  3OAN A;  1TXD A;  2CRF A;  1RJ2 A;  1PMS A;  1FB8 A;  2OQB A;  1DYN A;  2GCJ A;  5FI1 A;  4K81 A;  1H10 A;  4OSN A;  4DIX A;  1EGX A;  2NBV A;  2ROV A;  1ZC4 B;  2DHI A;  3A98 B;  1UPR A;  2AL6 A;  1TQZ A;  3NWD A;  4Z2N A;  1MIZ B;  3KRW A;  2LKO A;  5D3V A;  4HB4 B;  1MIX A;  1FHW A;  3D8F A;  1V5M A;  2Z13 A;  4DX9 0;  3TFM A;  2I5F A;  5KQ4 A;  3D8E A;  4KHB B;  4EJN A;  4ZRK A;  1J0W A;  4GXB A;  3AU4 A;  3DXC A;  2DTC A;  4MY6 A;  2R2Y A;  2D9V A;  2D9Y A;  1BTN A;  2N23 A;  2RUK B;  2COC A;  1GC6 A;  2ELA A;  4HDO A;  4PNK A;  5CLQ B;  2YT1 A;  2H7D A;  1KI1 B;  4P7I A;  4CHM A;  1MI1 A;  1MPH A;  2DLW A;  5IRS A;  2ZPY A;  1DDM A;  3FEH A;  5DI9 B;  2D9W A;  1WGU A;  3CXB B;  3B77 A;  1ZC3 B;  1NU2 A;  1FGZ A;  4CSQ A;  5JHH A;  3U7D A;  1PFJ A;  4GZU A;  2L1C A;  3D8D A;  3PZD A;  1LW3 A;  2EC1 A;  2YS1 A;  3P7Z A;  1LB1 A;  1W1H A;  3HIE A;  2MFQ A;  1I2H A;  3BJI A;  2FJU B;  1KZG A;  3ODX A;  4ZRI A;  2UZS A;  5CLL B;  4IFS A;  5DIF B;  2Y8F A;  2I5C A;  3TCA A;  4XWX A;  3AU5 A;  1UNP A;  2Q13 A;  1H4R A;  2M38 A;  1SHC A;  4OT1 A;  2K00 A;  2BCJ A;  5DHA B;  2I1K A;  1B55 A;  4A6F B;  4YON A;  2COA A;  3G9W A;  5J3Y A;  2DYQ A;  3SYX A;  2RRF A;  3RCP A;  2JP2 A;  2DYN A;  2YVC A;  2P0F A;  4L6E A;  2UVM A;  2DKQ A;  2KIE A;  4K2P A;  3FSS A;  1X1F A;  2YT0 A;  3HQC A;  1W1D A;  1BTK A;  1MK9 B;  1XKE A;  1FAO A;  2GJY A;  1W1G A;  5D3Y A;  1DDV A;  2D11 A;  2DX1 A;  2M14 A;  3A8Q A;  4F7U P;  3VOQ A;  4GN1 A;  1P5T A;  2EMT A;  2ZKM X;  1P3R A;  3KRX A;  2D2Q A;  3N7C A;  5LG4 B;  4D6W A;  1WJ1 A;  3PG7 A;  2RSG A;  1ZM0 A;  2NZ8 B;  4KVG B;  2Z0O A;  5FI0 A;  2QKL A;  5DHF B;  2AEH A;  1RRP B;  2D9Z A;  5C5B A;  2VKI A;  1FHO A;  2EMS A;  1AQC A;  1NTY A;  2KR0 A;  3ULC A;  2RGN B;  2Z4D A;  1Y19 B;  3HW2 B;  2I1J A;  2G35 A;  3X23 A;  2Z0Q A;  4C0A A;  4A6F A;  3BIN A;  5HE1 A;  2GUM A;  2LG1 A;  4HAU B;  1U5G A;  1I7A A;  2NMB A;  4Z2M B;  2YT2 A;  5LON B;  2VRW B;  3SNH A;  4A6H A;  3SO6 A;  1AWE A;  2GCL A;  2DHK A;  3KY9 A;  1U2B A;  3QWM A;  1Q67 A;  1UPQ A;  1X11 A;  1XOD A;  1SGH A;  3ZDT A;  2KUQ A;  4K2O A;  5JHG A;  1U29 A;  2J0K A;  4GMX B;  3TO1 A;  5KQ1 A;  1K5G B;  3GYO A;  3U8Z A;  4A5K A;  3WYF B;  1WJM A;  2CAY A;  3UZT A;  3LJU X;  5HE2 A;  3V5W A;  2CY5 A;  3FVC A;  2J0M A;  4GPT B;  2LYD A;  1UEF A;  4GMV A;  4HHV A;  3PEG A;  4GOU A;  1ZSQ A;  1NI2 A;  1P6S A;  1PLS A;  4WJ7 A;  2VSZ A;  1Y5O A;  5LOP B;  5D3W A;  1U5E A;  1X05 A;  2GS0 A;  2MDX A;  1X1G A;  2YRY A;  4HAX B;  3DCX A;  2X18 A;  3CIK A;  4GNK B;  5L81 A;  2W2X D;  2YSZ A;  4L1R A;  1WG7 A;  2W2X C;  2Z0P A; 
#chains in the Genus database with same CATH homology
 2DA0 A;  4HDQ A;  2COF A;  4TYZ A;  5JLJ B;  2DKP A;  2H7E A;  2P8V A;  1DBH A;  2KGX B;  4HAW B;  1UNQ A;  2DFK A;  1DDW A;  3IVF A;  4F7H A;  1FGY A;  3GYP A;  4CYE A;  3PVU A;  4CHJ A;  4BBK A;  4HB0 B;  3SUZ A;  3QBV B;  4WVF B;  1V88 A;  2RLO A;  4EMO A;  3QIJ A;  2MWN B;  4NY0 A;  4DX8 A;  2MKR A;  3HK0 A;  4NSW A;  3TW1 A;  2K2U A;  3F5R A;  5J3Q A;  1XR0 B;  1V61 A;  4IOY X;  2HTH B;  1WI1 A;  4ZRJ A;  4B6H A;  2W2W A;  2D10 A;  5C16 A;  4K17 A;  1U5D A;  3DXD A;  3M1I B;  5J3T A;  2YS3 A;  2ADZ A;  1XD4 A;  2PZ1 A;  3FM8 C;  1XX0 A;  2IYB A;  1BAK A;  1K5D B;  1M7E A;  4HB3 B;  1V5U A;  3PVL A;  1QQG A;  3F0W A;  4TKN A;  4DXA B;  1ZVR A;  2RVB B;  2FJL A;  2ELB A;  5KCV A;  3KSY A;  1OY2 A;  1V89 A;  1ISN A;  4KHO A;  2EJ8 A;  1KZ7 A;  1MAI A;  2IFS A;  4DBB A;  2LUL A;  1V5P A;  1EVH A;  5D27 A;  2OTX A;  4HB2 B;  2DX5 A;  1OQN A;  1WGQ A;  1X86 A;  4H8S A;  3A8P A;  3MPX A;  4F7G A;  3AJ4 A;  1MK7 B;  2HE7 A;  1FHX A;  3TVV A;  2KUP A;  2ROZ B;  4KHA A;  2J0J A;  3PVW A;  5HE3 A;  3O96 A;  1DRO A;  2P0D A;  4HAY B;  2QKM A;  4MK0 A;  2KCJ A;  2XQN M;  2J59 M;  2CY4 A;  1UNR A;  1IRS A;  1OMW A;  2UZR A;  5C79 A;  1Z87 A;  3ODO A;  1J19 A;  1MKE A;  3PSC A;  4HAT B;  2L2I A;  3P6A A;  5JP4 A;  1U5F A;  1WVH A;  4PQ0 A;  3T06 A;  2LOZ A;  4KAX B;  2LOX A;  3DXE A;  1FOE A;  3MDB C;  5DH9 B;  3ODW A;  1GG3 A;  4WSF A;  5C5B B;  1U27 A;  3NSU A;  4A6K A;  2R0D A;  1E5W A;  4HAV B;  2RNR B;  4EKU A;  3WA0 A;  3ZVR A;  5C6R A;  2P0H A;  4Y94 A;  2DN6 A;  2V76 A;  1N3H A;  1QC6 A;  3ULB A;  3KZ1 A;  3VIA A;  2YF0 A;  4HAZ B;  1XCG A;  2Y7B A;  4D0N B;  1NTV A;  1TJ6 A;  5GOW B;  2N0Y A;  5EFX A;  1GC7 A;  1BWN A;  2Y8G A;  2K2J A;  4YL8 A;  2R09 A;  3ML4 A;  4MT7 A;  5HE0 A;  2E2X A;  5D3X A;  2DHJ A;  1EF1 A;  4IAP A;  2COD A;  1M7R A;  2YS5 A;  3PP2 A;  2D9X A;  1EAZ A;  3SV1 A;  3OAN A;  2D4Q A;  1TXD A;  2CRF A;  1RJ2 A;  1PMS A;  1FB8 A;  2OQB A;  1DYN A;  2GCJ A;  5FI1 A;  4K81 A;  1H10 A;  1EGX A;  2ROV A;  1ZC4 B;  2DHI A;  3A98 B;  1UPR A;  2AL6 A;  1TQZ A;  4Z2N A;  1MIZ B;  3KRW A;  2LKO A;  5D3V A;  4HB4 B;  1MIX A;  1FHW A;  3D8F A;  1V5M A;  4DX9 0;  3TFM A;  2I5F A;  5KQ4 A;  3D8E A;  4KHB B;  4EJN A;  4ZRK A;  1J0W A;  4GXB A;  3AU4 A;  3DXC A;  2DTC A;  4MY6 A;  2D9V A;  2D9Y A;  1BTN A;  2N23 A;  2RUK B;  2COC A;  1GC6 A;  2ELA A;  4HDO A;  4PNK A;  5CLQ B;  2YT1 A;  2H7D A;  1KI1 B;  4P7I A;  4CHM A;  1MPH A;  2DLW A;  2ZPY A;  1DDM A;  3FEH A;  5DI9 B;  2D9W A;  1WGU A;  3CXB B;  1ZC3 B;  1NU2 A;  1FGZ A;  5JHH A;  3U7D A;  1PFJ A;  4GZU A;  2L1C A;  3D8D A;  3PZD A;  1LW3 A;  3P7Z A;  2EC1 A;  2YS1 A;  1LB1 A;  1W1H A;  2MFQ A;  1I2H A;  3BJI A;  1KZG A;  3ODX A;  4ZRI A;  2UZS A;  5CLL B;  4IFS A;  5DIF B;  2Y8F A;  2I5C A;  3TCA A;  4XWX A;  3AU5 A;  1UNP A;  2Q13 A;  1H4R A;  2M38 A;  1SHC A;  2K00 A;  2BCJ A;  5DHA B;  2I1K A;  1B55 A;  4A6F B;  4YON A;  2COA A;  3G9W A;  5J3Y A;  2DYQ A;  3SYX A;  3RCP A;  2JP2 A;  2DYN A;  2YVC A;  2P0F A;  4L6E A;  2UVM A;  2DKQ A;  4K2P A;  3FSS A;  1X1F A;  2YT0 A;  3HQC A;  1W1D A;  1BTK A;  1MK9 B;  1XKE A;  1FAO A;  2GJY A;  1W1G A;  5D3Y A;  1DDV A;  2D11 A;  2DX1 A;  2M14 A;  3A8Q A;  4F7U P;  3VOQ A;  4GN1 A;  1P5T A;  2EMT A;  1P3R A;  3KRX A;  2D2Q A;  3N7C A;  1WJ1 A;  3PG7 A;  2RSG A;  1ZM0 A;  2NZ8 B;  4KVG B;  2Z0O A;  5FI0 A;  2QKL A;  5DHF B;  2AEH A;  1RRP B;  2D9Z A;  5C5B A;  2VKI A;  1FHO A;  2EMS A;  1AQC A;  1NTY A;  3ULC A;  2RGN B;  1Y19 B;  3HW2 B;  2I1J A;  2G35 A;  3X23 A;  2Z0Q A;  4C0A A;  4A6F A;  3BIN A;  5HE1 A;  2LG1 A;  4HAU B;  1U5G A;  1I7A A;  2NMB A;  4Z2M B;  5LON B;  2VRW B;  3SNH A;  4A6H A;  3SO6 A;  1AWE A;  2GCL A;  2DHK A;  3KY9 A;  1U2B A;  3QWM A;  1Q67 A;  1UPQ A;  1X11 A;  1XOD A;  1SGH A;  3ZDT A;  4K2O A;  5JHG A;  1U29 A;  2J0K A;  4GMX B;  3TO1 A;  5KQ1 A;  1K5G B;  3GYO A;  3U8Z A;  4A5K A;  3WYF B;  1WJM A;  2CAY A;  3UZT A;  3LJU X;  5HE2 A;  3V5W A;  2CY5 A;  2J0M A;  4GPT B;  2LYD A;  1UEF A;  4GMV A;  4HHV A;  3PEG A;  1ZSQ A;  1NI2 A;  1P6S A;  1PLS A;  4WJ7 A;  2VSZ A;  1Y5O A;  5LOP B;  5D3W A;  1U5E A;  1X05 A;  2GS0 A;  2MDX A;  1X1G A;  2YRY A;  4HAX B;  2X18 A;  3CIK A;  5L81 A;  2W2X D;  2YSZ A;  1WG7 A;  2W2X C;  2Z0P A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

4Y94A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations