4A5KA

Structural analyses of slm1-ph domain demonstrate ligand binding in the non-canonical site
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
115
structure length
115
Chain Sequence
FTEIKSGFLERRSKFLKSYSKGYYVLTPNFLHEFKTADRKKDLVPVMSLALSECTVTEHSRKNSTSSPNSTGSDAKFVLHAKQNGIIRRGHNWVFKADSYESMMSWFDNLKILTS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Analyses of Slm1-Ph Domain Demonstrate Ligand Binding in the Non-Canonical Site
pubmed doi rcsb
molecule tags Signaling protein
source organism Saccharomyces cerevisiae
molecule keywords PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE-BINDING PROTEIN SLM 1
total genus 25
structure length 115
sequence length 115
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2011-10-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 4a5kA00
3D8EA 4HDQA 2P0FA 1KZ7A 5DH9B 1FHOA 4A6FB 2OTXA 3FSSA 4HAYB 3TVVA 5L81A 2R09A 1FB8A 1M7RA 5DI9B 4IOYX 1W1GA 3V5WA 2D11A 1PLSA 2H7DA 4MY6A 1DDMA 1UNPA 1I7AA 2J0MA 2UVMA 5D3XA 2LG1A 1SGHA 2K2UA 1U5EA 3U7DA 3ULCA 2GJYA 1MAIA 2J59M 3SUZA 1MK7B 4D0NB 5HE1A 3KSYA 4DX8A 2DKPA 3ODWA 3BJIA 3F0WA 3QWMA 2W2XC 1K5DB 4K81A 4CHJA 2MKRA 1BWNA 2VKIA 4H8SA 1UPQA 2L2IA 1TXDA 2UZSA 5CLLB 1GC6A 5CLQB 1MIXA 5HE0A 2DKQA 1XODA 4P7IA 4MT7A 2YVCA 3GYOA 2OQBA 1IRSA 1Z87A 4YONA 1MIZB 1BAKA 2R0DA 3AJ4A 3G9WA 4GMXB 2YT0A 1W1HA 2GCJA 1UNRA 3O96A 1X05A 1ZM0A 5DHAB 3KY9A 4C0AA 4K2OA 3PVLA 3NSUA 2LKOA 4IAPA 1V88A 1BTKA 4DXAB 4L6EA 5DHFB 3DXCA 4HDOA 5C16A 1V5PA 3A8QA 3LJUX 5EFXA 2QKLA 3QBVB 2RLOA 2D9ZA 3UZTA 5GOWB 1UNQA 2COFA 2UZRA 3RCPA 2HTHB 3D8FA 1I2HA 3ZVRA 2N0YA 3MPXA 2K2JA 4BBKA 3TW1A 3ODOA 4HB3B 5FI0A 1H10A 4EJNA 5KQ1A 1P3RA 1M7EA 1X1FA 3FM8C 1DDVA 1WJ1A 4WSFA 1J0WA 2I5CA 4GMVA 1MPHA 4KHAA 2I1JA 1ZC4B 2KUPA 2BCJA 1K5GB 3PSCA 2AEHA 2M38A 1QC6A 3SO6A 4A6HA 2CODA 4KAXB 4F7GA 5KCVA 3SYXA 4PQ0A 3ULBA 5HE2A 4YL8A 1FGZA 2AL6A 2M14A 1DDWA 2DN6A 2MDXA 2RSGA 3HQCA 2DHKA 5C6RA 4HAUB 2P0HA 2QKMA 2D10A 2CRFA 1U5DA 1V61A 2D9XA 1WGQA 1ZC3B 1FGYA 1WG7A 1XKEA 2RUKB 1XR0B 1Y5OA 3KZ1A 3TFMA 1NI2A 1WGUA 4HB4B 3PG7A 3P6AA 3P7ZA 2COCA 2YRYA 1MKEA 4CYEA 5LONB 4ZRKA 2YS3A 2D9WA 4HATB 5DIFB 3M1IB 4HAXB 1LB1A 3D8DA 4Y94A 3SNHA 3PVUA 2EJ8A 4GXBA 1ZVRA 1KI1B 2YS5A 1U2BA 1N3HA 1X86A 1DROA 2Y7BA 1ZSQA 3GYPA 5KQ4A 4CHMA 3KRXA 4XWXA 5D27A 3AU5A 4HAVB 1U5FA 5D3WA 2G35A 2YT1A 2ZPYA 1AQCA 2J0KA 2JP2A 3ZDTA 3PP2A 4TYZA 2EMSA 2LOXA 1EF1A 3MDBC 2J0JA 2LYDA 4Z2MB 2ROZB 3VOQA 2LOZA 2RGNB 2DYNA 1XCGA 2DLWA 2CY5A 5C79A 1SHCA 4F7HA 2FJLA 1TJ6A 2GS0A 3HK0A 2DFKA 4F7UP 1MK9B 1V5UA 2IFSA 5D3YA 4Z2NA 4HHVA 4A6KA 2E2XA 1X11A 2KCJA 3CIKA 2IYBA 4NSWA 5JHGA 4B6HA 5J3QA 1QQGA 1UPRA 2GCLA 2ADZA 2DHIA 4A6FA 2Z0QA 2Y8GA 1TQZA 2VRWB 2W2WA 4K2PA 4KHBB 1Q67A 3PEGA 4K17A 1ISNA 5JLJB 1FHWA 2DA0A 4HAZB 2DHJA 4GZUA 1X1GA 4KVGB 1OQNA 1BTNA 4GPTB 5J3YA 5C5BB 1PMSA 2RNRB 3A98B 1AWEA 2D9VA 2DX1A 3F5RA 3FEHA 1V5MA 1EAZA 2K00A 3KRWA 1P6SA 1OY2A 1WJMA 5J3TA 2XQNM 2Z0OA 4ZRJA 1RJ2A 1FAOA 2P8VA 2EMTA 2MWNB 2ROVA 2YF0A 2NZ8B 2V76A 1P5TA 1Y19B 3BINA 3TO1A 4WVFB 1LW3A 4WJ7A 2MFQA 3HW2B 3IVFA 3WYFB 1DBHA 3DXEA 3U8ZA 1NU2A 1WI1A 4HB0B 3N7CA 1NTVA 1U27A 4DBBA 1RRPB 2CAYA 3QIJA 1DYNA 2EC1A 2X18A 1J19A 2ELBA 3OANA 3X23A 4NY0A 4EMOA 5HE3A 1U5GA 3AU4A 1FOEA 2PZ1A 3SV1A 1V89A 3PZDA 1XD4A 5JHHA 1PFJA 1NTYA 1W1DA 3ML4A 3CXBB 1B55A 2COAA 1GC7A 4KHOA 5JP4A 2RVBB 1KZGA 4PNKA 3A8PA 2HE7A 2D9YA 2YSZA 3DXDA 1FHXA 2I1KA 5FI1A 2D4QA 2Q13A 5LOPB 2N23A 2L1CA 2LULA 4MK0A 2VSZA 4EKUA 2KGXB 4GN1A 3ODXA 1H4RA 1OMWA 2YS1A 2Y8FA 1EVHA 2H7EA 2Z0PA 1EGXA 3VIAA 1XX0A 2CY4A 3WA0A 2NMBA 3PVWA 2DTCA 2I5FA 4ZRIA 2W2XD 1U29A 2DX5A 3TCAA 1UEFA 2D2QA 2P0DA 2DYQA 1WVHA 4TKNA 4A5KA 5D3VA 2ELAA 4HB2B 1E5WA 4IFSA 1GG3A 5C5BA 4DX90 3T06A 4HAWB
chains in the Genus database with same CATH superfamily
3D8EA 4HDQA 2P0FA 3DCXA 1KZ7A 5DH9B 1FHOA 4A6FB 2OTXA 3FSSA 4HAYB 3TVVA 5L81A 2R09A 1FB8A 1M7RA 5DI9B 4IOYX 1W1GA 3V5WA 2D11A 1PLSA 2H7DA 4MY6A 1DDMA 1UNPA 1I7AA 2J0MA 2UVMA 5D3XA 2LG1A 1SGHA 2K2UA 1U5EA 3U7DA 3ULCA 2GJYA 2Z14A 1MAIA 2J59M 3SUZA 1MK7B 4D0NB 5HE1A 3KSYA 4DX8A 2DKPA 3ODWA 3A58A 3BJIA 3F0WA 3QWMA 2W2XC 1K5DB 4K81A 4CHJA 2MKRA 1ZYIA 1BWNA 3HSAA 2VKIA 4H8SA 1UPQA 2L2IA 1TXDA 2UZSA 5CLLB 1GC6A 5CLQB 1MIXA 5HE0A 2DKQA 1XODA 3U12A 4P7IA 4MT7A 2YVCA 3GYOA 2OQBA 1IRSA 1Z87A 4YONA 1MIZB 1BAKA 2R0DA 3AJ4A 3G9WA 4GMXB 2YT0A 1W1HA 2ZKMX 2GCJA 2K8EA 1UNRA 3O96A 1X05A 1ZM0A 5DHAB 3KY9A 4C0AA 4K2OA 3PVLA 3NSUA 2FJUB 2LKOA 4IAPA 1V88A 1BTKA 4DXAB 4L6EA 5DHFB 3DXCA 4HDOA 5C16A 1V5PA 3A8QA 3LJUX 5EFXA 2QKLA 4QJ5B 3QBVB 2RLOA 2D9ZA 3UZTA 5GOWB 1UNQA 2COFA 2UZRA 3NWDA 3RCPA 2HTHB 3D8FA 1I2HA 3ZVRA 2N0YA 3MPXA 2K2JA 4BBKA 3TW1A 3ODOA 4HB3B 5FI0A 1H10A 3NWFA 4OSNA 4EJNA 5KQ1A 1P3RA 1M7EA 1X1FA 3FM8C 1DDVA 1WJ1A 4WSFA 1J0WA 2I5CA 4KHBA 4GMVA 2KUQA 1MPHA 4KHAA 2I1JA 1MI1A 1ZC4B 2KUPA 2Z4DA 2BCJA 1K5GB 3PSCA 2AEHA 2M38A 1QC6A 3SO6A 4A6HA 2CODA 4KAXB 4F7GA 5KCVA 3SYXA 4PQ0A 3ULBA 5HE2A 4YL8A 1FGZA 2AL6A 2M14A 1DDWA 2DN6A 2MDXA 2RSGA 3HQCA 2DHKA 5C6RA 4HAUB 2P0HA 1T77A 2QKMA 2D10A 2CRFA 1U5DA 1V61A 2D9XA 1WGQA 1ZC3B 1FGYA 1WG7A 1XKEA 2RUKB 4GNKB 1XR0B 1Y5OA 3KZ1A 3TFMA 1NI2A 1WGUA 2Z13A 4HB4B 2Z59A 3PG7A 3P6AA 3P7ZA 2YT2A 2COCA 4OT1A 2YRYA 1MKEA 4CYEA 5LONB 4ZRKA 2YS3A 2D9WA 4HATB 5DIFB 3M1IB 4HAXB 1LB1A 3D8DA 4Y94A 3SNHA 3PVUA 2EJ8A 4GXBA 1ZVRA 1KI1B 2YS5A 1U2BA 4QXAB 1N3HA 1X86A 4L1RA 1DROA 2Y7BA 1ZSQA 3GYPA 5KQ4A 4CHMA 3KRXA 4QJ3B 4XWXA 5D27A 3AU5A 4HAVB 1U5FA 2KIEA 5D3WA 2G35A 2YT1A 2ZPYA 1AQCA 3FVCA 2J0KA 2JP2A 2K49A 3ZDTA 3PP2A 4TYZA 4QJ4B 2EMSA 3OHMB 2LOXA 1EF1A 3MDBC 5M4YB 2J0JA 2LYDA 4Z2MB 2ROZB 3VOQA 2LOZA 2RGNB 2DYNA 1XCGA 2DLWA 2CY5A 5C79A 1SHCA 4DIXA 4F7HA 2FJLA 1TJ6A 2GS0A 3HK0A 2DFKA 4F7UP 1MK9B 1V5UA 2IFSA 5D3YA 4Z2NA 4HHVA 4GOUA 3HIEA 4A6KA 2E2XA 1X11A 2KCJA 3CIKA 2IYBA 4NSWA 5I2SA 5JHGA 4B6HA 5J3QA 1QQGA 1UPRA 2GCLA 2ADZA 2DHIA 4A6FA 2Z0QA 2Y8GA 1TQZA 2VRWB 2W2WA 4K2PA 4KHBB 1Q67A 3PEGA 4K17A 1ISNA 5JLJB 1FHWA 2DA0A 4HAZB 2DHJA 4GZUA 1X1GA 4KVGB 1OQNA 1BTNA 4GPTB 5J3YA 5C5BB 1PMSA 2RNRB 3A98B 1AWEA 2D9VA 2DX1A 3F5RA 3FEHA 1V5MA 1EAZA 2K00A 3KRWA 4HSIA 1P6SA 1OY2A 1WJMA 5J3TA 2XQNM 2Z0OA 4ZRJA 1RJ2A 1FAOA 2P8VA 2EMTA 2MWNB 2ROVA 2YF0A 2NZ8B 2V76A 1P5TA 1Y19B 2RRFA 3BINA 4WVFB 3TO1A 1LW3A 2KIGA 4WJ7A 2MFQA 3HW2B 3IVFA 3WYFB 1DBHA 5I2MA 3DXEA 5LG4B 3U8ZA 1NU2A 1WI1A 4HB0B 3N7CA 1NTVA 1U27A 2NBVA 4DBBA 1RRPB 2CAYA 3QIJA 1DYNA 2EC1A 2X18A 1J19A 2ELBA 3OANA 3X23A 4NY0A 2R2YA 3NW8A 4EMOA 5HE3A 1U5GA 3AU4A 1FOEA 2PZ1A 3SV1A 3B77A 1V89A 3PZDA 1XD4A 5JHHA 1PFJA 1NTYA 1W1DA 3ML4A 3NWAA 3CXBB 2GUMA 1B55A 2COAA 1GC7A 4KHOA 5JP4A 2RVBB 1KZGA 4PNKA 3A8PA 2HE7A 2D9YA 2YSZA 3DXDA 1FHXA 2I1KA 5FI1A 2D4QA 2Q13A 5LOPB 2N23A 2L1CA 2LULA 4MK0A 2VSZA 4EKUA 2KGXB 4GN1A 3ODXA 1H4RA 1OMWA 2YS1A 2Y8FA 1EVHA 2H7EA 2Z0PA 1EGXA 3VIAA 1XX0A 2CY4A 3WA0A 2NMBA 4CSQA 3PVWA 2KR0A 2DTCA 2I5FA 4ZRIA 2W2XD 1U29A 2DX5A 3TCAA 4D6WA 1UEFA 2D2QA 2P0DA 2DYQA 1WVHA 4TKNA 4A5KA 5IRSA 5D3VA 2ELAA 4HB2B 1E5WA 4IFSA 1GG3A 5C5BA 4DX90 3T06A 4HAWB
chains in the Genus database with same CATH topology
3D8EA 4HDQA 2P0FA 1KZ7A 5DH9B 1FHOA 4A6FB 2OTXA 3FSSA 4HAYB 3TVVA 5L81A 2R09A 1FB8A 1M7RA 5DI9B 4IOYX 1W1GA 3V5WA 2D11A 1PLSA 2H7DA 4MY6A 1DDMA 1UNPA 1I7AA 2J0MA 2UVMA 5D3XA 2LG1A 1SGHA 2K2UA 1U5EA 3U7DA 3ULCA 2GJYA 1MAIA 2J59M 3SUZA 1MK7B 4D0NB 5HE1A 3KSYA 4DX8A 2DKPA 3ODWA 3BJIA 3F0WA 3QWMA 2W2XC 1K5DB 4K81A 4CHJA 2MKRA 1BWNA 2VKIA 4H8SA 1UPQA 2L2IA 1TXDA 2UZSA 5CLLB 1GC6A 5CLQB 1MIXA 5HE0A 2DKQA 1XODA 4P7IA 4MT7A 2YVCA 3GYOA 2OQBA 1IRSA 1Z87A 4YONA 1MIZB 1BAKA 2R0DA 3AJ4A 3G9WA 4GMXB 2YT0A 1W1HA 2GCJA 1UNRA 3O96A 1X05A 1ZM0A 5DHAB 3KY9A 4C0AA 4K2OA 3PVLA 3NSUA 2LKOA 4IAPA 1V88A 1BTKA 4DXAB 4L6EA 5DHFB 3DXCA 4HDOA 5C16A 1V5PA 3A8QA 3LJUX 5EFXA 2QKLA 3QBVB 2RLOA 2D9ZA 3UZTA 5GOWB 1UNQA 2COFA 2UZRA 3RCPA 2HTHB 3D8FA 1I2HA 3ZVRA 2N0YA 3MPXA 2K2JA 4BBKA 3TW1A 3ODOA 4HB3B 5FI0A 1H10A 4EJNA 5KQ1A 1P3RA 1M7EA 1X1FA 3FM8C 1DDVA 1WJ1A 4WSFA 1J0WA 2I5CA 4GMVA 1MPHA 4KHAA 2I1JA 1ZC4B 2KUPA 2BCJA 1K5GB 3PSCA 2AEHA 2M38A 1QC6A 3SO6A 4A6HA 2CODA 4KAXB 4F7GA 5KCVA 3SYXA 4PQ0A 3ULBA 5HE2A 4YL8A 1FGZA 2AL6A 2M14A 1DDWA 2DN6A 2MDXA 2RSGA 3HQCA 2DHKA 5C6RA 4HAUB 2P0HA 2QKMA 2D10A 2CRFA 1U5DA 1V61A 2D9XA 1WGQA 1ZC3B 1FGYA 1WG7A 1XKEA 2RUKB 1XR0B 1Y5OA 3KZ1A 3TFMA 1NI2A 1WGUA 4HB4B 3PG7A 3P6AA 3P7ZA 2COCA 2YRYA 1MKEA 4CYEA 5LONB 4ZRKA 2YS3A 2D9WA 4HATB 5DIFB 3M1IB 4HAXB 1LB1A 3D8DA 4Y94A 3SNHA 3PVUA 2EJ8A 4GXBA 1ZVRA 1KI1B 2YS5A 1U2BA 1N3HA 1X86A 1DROA 2Y7BA 1ZSQA 3GYPA 5KQ4A 4CHMA 3KRXA 4XWXA 5D27A 3AU5A 4HAVB 1U5FA 5D3WA 2G35A 2YT1A 2ZPYA 1AQCA 2J0KA 2JP2A 3ZDTA 3PP2A 4TYZA 2EMSA 2LOXA 1EF1A 3MDBC 2J0JA 2LYDA 4Z2MB 2ROZB 3VOQA 2LOZA 2RGNB 2DYNA 1XCGA 2DLWA 2CY5A 5C79A 1SHCA 4F7HA 2FJLA 1TJ6A 2GS0A 3HK0A 2DFKA 4F7UP 1MK9B 1V5UA 2IFSA 5D3YA 4Z2NA 4HHVA 4A6KA 2E2XA 1X11A 2KCJA 3CIKA 2IYBA 4NSWA 5JHGA 4B6HA 5J3QA 1QQGA 1UPRA 2GCLA 2ADZA 2DHIA 4A6FA 2Z0QA 2Y8GA 1TQZA 2VRWB 2W2WA 4K2PA 4KHBB 1Q67A 3PEGA 4K17A 1ISNA 5JLJB 1FHWA 2DA0A 4HAZB 2DHJA 4GZUA 1X1GA 4KVGB 1OQNA 1BTNA 4GPTB 5J3YA 5C5BB 1PMSA 2RNRB 3A98B 1AWEA 2D9VA 2DX1A 3F5RA 3FEHA 1V5MA 1EAZA 2K00A 3KRWA 1P6SA 1OY2A 1WJMA 5J3TA 2XQNM 2Z0OA 4ZRJA 1RJ2A 1FAOA 2P8VA 2EMTA 2MWNB 2ROVA 2YF0A 2NZ8B 2V76A 1P5TA 1Y19B 3BINA 3TO1A 4WVFB 1LW3A 4WJ7A 2MFQA 3HW2B 3IVFA 3WYFB 1DBHA 3DXEA 3U8ZA 1NU2A 1WI1A 4HB0B 3N7CA 1NTVA 1U27A 4DBBA 1RRPB 2CAYA 3QIJA 1DYNA 2EC1A 2X18A 1J19A 2ELBA 3OANA 3X23A 4NY0A 4EMOA 5HE3A 1U5GA 3AU4A 1FOEA 2PZ1A 3SV1A 1V89A 3PZDA 1XD4A 5JHHA 1PFJA 1NTYA 1W1DA 3ML4A 3CXBB 1B55A 2COAA 1GC7A 4KHOA 5JP4A 2RVBB 1KZGA 4PNKA 3A8PA 2HE7A 2D9YA 2YSZA 3DXDA 1FHXA 2I1KA 5FI1A 2D4QA 2Q13A 5LOPB 2N23A 2L1CA 2LULA 4MK0A 2VSZA 4EKUA 2KGXB 4GN1A 3ODXA 1H4RA 1OMWA 2YS1A 2Y8FA 1EVHA 2H7EA 2Z0PA 1EGXA 3VIAA 1XX0A 2CY4A 3WA0A 2NMBA 3PVWA 2DTCA 2I5FA 4ZRIA 2W2XD 1U29A 2DX5A 3TCAA 1UEFA 2D2QA 2P0DA 2DYQA 1WVHA 4TKNA 4A5KA 5D3VA 2ELAA 4HB2B 1E5WA 4IFSA 1GG3A 5C5BA 4DX90 3T06A 4HAWB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3D8E A;  4HDQ A;  2P0F A;  1KZ7 A;  5DH9 B;  1FHO A;  4A6F B;  2OTX A;  3FSS A;  4HAY B;  3TVV A;  5L81 A;  2R09 A;  1FB8 A;  1M7R A;  5DI9 B;  4IOY X;  1W1G A;  3V5W A;  2D11 A;  1PLS A;  2H7D A;  4MY6 A;  1DDM A;  1UNP A;  1I7A A;  2J0M A;  2UVM A;  5D3X A;  2LG1 A;  1SGH A;  2K2U A;  1U5E A;  3U7D A;  3ULC A;  2GJY A;  1MAI A;  2J59 M;  3SUZ A;  1MK7 B;  4D0N B;  5HE1 A;  3KSY A;  4DX8 A;  2DKP A;  3ODW A;  3BJI A;  3F0W A;  3QWM A;  2W2X C;  1K5D B;  4K81 A;  4CHJ A;  2MKR A;  1BWN A;  2VKI A;  4H8S A;  1UPQ A;  2L2I A;  1TXD A;  2UZS A;  5CLL B;  1GC6 A;  5CLQ B;  1MIX A;  5HE0 A;  2DKQ A;  1XOD A;  4P7I A;  4MT7 A;  2YVC A;  3GYO A;  2OQB A;  1IRS A;  1Z87 A;  4YON A;  1MIZ B;  1BAK A;  2R0D A;  3AJ4 A;  3G9W A;  4GMX B;  2YT0 A;  1W1H A;  2GCJ A;  1UNR A;  3O96 A;  1X05 A;  1ZM0 A;  5DHA B;  3KY9 A;  4C0A A;  4K2O A;  3PVL A;  3NSU A;  2LKO A;  4IAP A;  1V88 A;  1BTK A;  4DXA B;  4L6E A;  5DHF B;  3DXC A;  4HDO A;  5C16 A;  1V5P A;  3A8Q A;  3LJU X;  5EFX A;  2QKL A;  3QBV B;  2RLO A;  2D9Z A;  3UZT A;  5GOW B;  1UNQ A;  2COF A;  2UZR A;  3RCP A;  2HTH B;  3D8F A;  1I2H A;  3ZVR A;  2N0Y A;  3MPX A;  2K2J A;  4BBK A;  3TW1 A;  3ODO A;  4HB3 B;  5FI0 A;  1H10 A;  4EJN A;  5KQ1 A;  1P3R A;  1M7E A;  1X1F A;  3FM8 C;  1DDV A;  1WJ1 A;  4WSF A;  1J0W A;  2I5C A;  4GMV A;  1MPH A;  4KHA A;  2I1J A;  1ZC4 B;  2KUP A;  2BCJ A;  1K5G B;  3PSC A;  2AEH A;  2M38 A;  1QC6 A;  3SO6 A;  4A6H A;  2COD A;  4KAX B;  4F7G A;  5KCV A;  3SYX A;  4PQ0 A;  3ULB A;  5HE2 A;  4YL8 A;  1FGZ A;  2AL6 A;  2M14 A;  1DDW A;  2DN6 A;  2MDX A;  2RSG A;  3HQC A;  2DHK A;  5C6R A;  4HAU B;  2P0H A;  2QKM A;  2D10 A;  2CRF A;  1U5D A;  1V61 A;  2D9X A;  1WGQ A;  1ZC3 B;  1FGY A;  1WG7 A;  1XKE A;  2RUK B;  1XR0 B;  1Y5O A;  3KZ1 A;  3TFM A;  1NI2 A;  1WGU A;  4HB4 B;  3PG7 A;  3P6A A;  3P7Z A;  2COC A;  2YRY A;  1MKE A;  4CYE A;  5LON B;  4ZRK A;  2YS3 A;  2D9W A;  4HAT B;  5DIF B;  3M1I B;  4HAX B;  1LB1 A;  3D8D A;  4Y94 A;  3SNH A;  3PVU A;  2EJ8 A;  4GXB A;  1ZVR A;  1KI1 B;  2YS5 A;  1U2B A;  1N3H A;  1X86 A;  1DRO A;  2Y7B A;  1ZSQ A;  3GYP A;  5KQ4 A;  4CHM A;  3KRX A;  4XWX A;  5D27 A;  3AU5 A;  4HAV B;  1U5F A;  5D3W A;  2G35 A;  2YT1 A;  2ZPY A;  1AQC A;  2J0K A;  2JP2 A;  3ZDT A;  3PP2 A;  4TYZ A;  2EMS A;  2LOX A;  1EF1 A;  3MDB C;  2J0J A;  2LYD A;  4Z2M B;  2ROZ B;  3VOQ A;  2LOZ A;  2RGN B;  2DYN A;  1XCG A;  2DLW A;  2CY5 A;  5C79 A;  1SHC A;  4F7H A;  2FJL A;  1TJ6 A;  2GS0 A;  3HK0 A;  2DFK A;  4F7U P;  1MK9 B;  1V5U A;  2IFS A;  5D3Y A;  4Z2N A;  4HHV A;  4A6K A;  2E2X A;  1X11 A;  2KCJ A;  3CIK A;  2IYB A;  4NSW A;  5JHG A;  4B6H A;  5J3Q A;  1QQG A;  1UPR A;  2GCL A;  2ADZ A;  2DHI A;  4A6F A;  2Z0Q A;  2Y8G A;  1TQZ A;  2VRW B;  2W2W A;  4K2P A;  4KHB B;  1Q67 A;  3PEG A;  4K17 A;  1ISN A;  5JLJ B;  1FHW A;  2DA0 A;  4HAZ B;  2DHJ A;  4GZU A;  1X1G A;  4KVG B;  1OQN A;  1BTN A;  4GPT B;  5J3Y A;  5C5B B;  1PMS A;  2RNR B;  3A98 B;  1AWE A;  2D9V A;  2DX1 A;  3F5R A;  3FEH A;  1V5M A;  1EAZ A;  2K00 A;  3KRW A;  1P6S A;  1OY2 A;  1WJM A;  5J3T A;  2XQN M;  2Z0O A;  4ZRJ A;  1RJ2 A;  1FAO A;  2P8V A;  2EMT A;  2MWN B;  2ROV A;  2YF0 A;  2NZ8 B;  2V76 A;  1P5T A;  1Y19 B;  3BIN A;  3TO1 A;  4WVF B;  1LW3 A;  4WJ7 A;  2MFQ A;  3HW2 B;  3IVF A;  3WYF B;  1DBH A;  3DXE A;  3U8Z A;  1NU2 A;  1WI1 A;  4HB0 B;  3N7C A;  1NTV A;  1U27 A;  4DBB A;  1RRP B;  2CAY A;  3QIJ A;  1DYN A;  2EC1 A;  2X18 A;  1J19 A;  2ELB A;  3OAN A;  3X23 A;  4NY0 A;  4EMO A;  5HE3 A;  1U5G A;  3AU4 A;  1FOE A;  2PZ1 A;  3SV1 A;  1V89 A;  3PZD A;  1XD4 A;  5JHH A;  1PFJ A;  1NTY A;  1W1D A;  3ML4 A;  3CXB B;  1B55 A;  2COA A;  1GC7 A;  4KHO A;  5JP4 A;  2RVB B;  1KZG A;  4PNK A;  3A8P A;  2HE7 A;  2D9Y A;  2YSZ A;  3DXD A;  1FHX A;  2I1K A;  5FI1 A;  2D4Q A;  2Q13 A;  5LOP B;  2N23 A;  2L1C A;  2LUL A;  4MK0 A;  2VSZ A;  4EKU A;  2KGX B;  4GN1 A;  3ODX A;  1H4R A;  1OMW A;  2YS1 A;  2Y8F A;  1EVH A;  2H7E A;  2Z0P A;  1EGX A;  3VIA A;  1XX0 A;  2CY4 A;  3WA0 A;  2NMB A;  3PVW A;  2DTC A;  2I5F A;  4ZRI A;  2W2X D;  1U29 A;  2DX5 A;  3TCA A;  1UEF A;  2D2Q A;  2P0D A;  2DYQ A;  1WVH A;  4TKN A;  4A5K A;  5D3V A;  2ELA A;  4HB2 B;  1E5W A;  4IFS A;  1GG3 A;  5C5B A;  4DX9 0;  3T06 A;  4HAW B; 
#chains in the Genus database with same CATH topology
 3D8E A;  4HDQ A;  2P0F A;  3DCX A;  1KZ7 A;  5DH9 B;  1FHO A;  4A6F B;  2OTX A;  3FSS A;  4HAY B;  3TVV A;  5L81 A;  2R09 A;  1FB8 A;  1M7R A;  5DI9 B;  4IOY X;  1W1G A;  3V5W A;  2D11 A;  1PLS A;  2H7D A;  4MY6 A;  1DDM A;  1UNP A;  1I7A A;  2J0M A;  2UVM A;  5D3X A;  2LG1 A;  1SGH A;  2K2U A;  1U5E A;  3U7D A;  3ULC A;  2GJY A;  2Z14 A;  1MAI A;  2J59 M;  3SUZ A;  1MK7 B;  4D0N B;  5HE1 A;  3KSY A;  4DX8 A;  2DKP A;  3ODW A;  3A58 A;  3BJI A;  3F0W A;  3QWM A;  2W2X C;  1K5D B;  4K81 A;  4CHJ A;  2MKR A;  1ZYI A;  1BWN A;  3HSA A;  2VKI A;  4H8S A;  1UPQ A;  2L2I A;  1TXD A;  2UZS A;  5CLL B;  1GC6 A;  5CLQ B;  1MIX A;  5HE0 A;  2DKQ A;  1XOD A;  3U12 A;  4P7I A;  4MT7 A;  2YVC A;  3GYO A;  2OQB A;  1IRS A;  1Z87 A;  4YON A;  1MIZ B;  1BAK A;  2R0D A;  3AJ4 A;  3G9W A;  4GMX B;  2YT0 A;  1W1H A;  2ZKM X;  2GCJ A;  2K8E A;  1UNR A;  3O96 A;  1X05 A;  1ZM0 A;  5DHA B;  3KY9 A;  4C0A A;  4K2O A;  3PVL A;  3NSU A;  2FJU B;  2LKO A;  4IAP A;  1V88 A;  1BTK A;  4DXA B;  4L6E A;  5DHF B;  3DXC A;  4HDO A;  5C16 A;  1V5P A;  3A8Q A;  3LJU X;  5EFX A;  2QKL A;  4QJ5 B;  3QBV B;  2RLO A;  2D9Z A;  3UZT A;  5GOW B;  1UNQ A;  2COF A;  2UZR A;  3NWD A;  3RCP A;  2HTH B;  3D8F A;  1I2H A;  3ZVR A;  2N0Y A;  3MPX A;  2K2J A;  4BBK A;  3TW1 A;  3ODO A;  4HB3 B;  5FI0 A;  1H10 A;  3NWF A;  4OSN A;  4EJN A;  5KQ1 A;  1P3R A;  1M7E A;  1X1F A;  3FM8 C;  1DDV A;  1WJ1 A;  4WSF A;  1J0W A;  2I5C A;  4KHB A;  4GMV A;  2KUQ A;  1MPH A;  4KHA A;  2I1J A;  1MI1 A;  1ZC4 B;  2KUP A;  2Z4D A;  2BCJ A;  1K5G B;  3PSC A;  2AEH A;  2M38 A;  1QC6 A;  3SO6 A;  4A6H A;  2COD A;  4KAX B;  4F7G A;  5KCV A;  3SYX A;  4PQ0 A;  3ULB A;  5HE2 A;  4YL8 A;  1FGZ A;  2AL6 A;  2M14 A;  1DDW A;  2DN6 A;  2MDX A;  2RSG A;  3HQC A;  2DHK A;  5C6R A;  4HAU B;  2P0H A;  1T77 A;  2QKM A;  2D10 A;  2CRF A;  1U5D A;  1V61 A;  2D9X A;  1WGQ A;  1ZC3 B;  1FGY A;  1WG7 A;  1XKE A;  2RUK B;  4GNK B;  1XR0 B;  1Y5O A;  3KZ1 A;  3TFM A;  1NI2 A;  1WGU A;  2Z13 A;  4HB4 B;  2Z59 A;  3PG7 A;  3P6A A;  3P7Z A;  2YT2 A;  2COC A;  4OT1 A;  2YRY A;  1MKE A;  4CYE A;  5LON B;  4ZRK A;  2YS3 A;  2D9W A;  4HAT B;  5DIF B;  3M1I B;  4HAX B;  1LB1 A;  3D8D A;  4Y94 A;  3SNH A;  3PVU A;  2EJ8 A;  4GXB A;  1ZVR A;  1KI1 B;  2YS5 A;  1U2B A;  4QXA B;  1N3H A;  1X86 A;  4L1R A;  1DRO A;  2Y7B A;  1ZSQ A;  3GYP A;  5KQ4 A;  4CHM A;  3KRX A;  4QJ3 B;  4XWX A;  5D27 A;  3AU5 A;  4HAV B;  1U5F A;  2KIE A;  5D3W A;  2G35 A;  2YT1 A;  2ZPY A;  1AQC A;  3FVC A;  2J0K A;  2JP2 A;  2K49 A;  3ZDT A;  3PP2 A;  4TYZ A;  4QJ4 B;  2EMS A;  3OHM B;  2LOX A;  1EF1 A;  3MDB C;  5M4Y B;  2J0J A;  2LYD A;  4Z2M B;  2ROZ B;  3VOQ A;  2LOZ A;  2RGN B;  2DYN A;  1XCG A;  2DLW A;  2CY5 A;  5C79 A;  1SHC A;  4DIX A;  4F7H A;  2FJL A;  1TJ6 A;  2GS0 A;  3HK0 A;  2DFK A;  4F7U P;  1MK9 B;  1V5U A;  2IFS A;  5D3Y A;  4Z2N A;  4HHV A;  4GOU A;  3HIE A;  4A6K A;  2E2X A;  1X11 A;  2KCJ A;  3CIK A;  2IYB A;  4NSW A;  5I2S A;  5JHG A;  4B6H A;  5J3Q A;  1QQG A;  1UPR A;  2GCL A;  2ADZ A;  2DHI A;  4A6F A;  2Z0Q A;  2Y8G A;  1TQZ A;  2VRW B;  2W2W A;  4K2P A;  4KHB B;  1Q67 A;  3PEG A;  4K17 A;  1ISN A;  5JLJ B;  1FHW A;  2DA0 A;  4HAZ B;  2DHJ A;  4GZU A;  1X1G A;  4KVG B;  1OQN A;  1BTN A;  4GPT B;  5J3Y A;  5C5B B;  1PMS A;  2RNR B;  3A98 B;  1AWE A;  2D9V A;  2DX1 A;  3F5R A;  3FEH A;  1V5M A;  1EAZ A;  2K00 A;  3KRW A;  4HSI A;  1P6S A;  1OY2 A;  1WJM A;  5J3T A;  2XQN M;  2Z0O A;  4ZRJ A;  1RJ2 A;  1FAO A;  2P8V A;  2EMT A;  2MWN B;  2ROV A;  2YF0 A;  2NZ8 B;  2V76 A;  1P5T A;  1Y19 B;  2RRF A;  3BIN A;  4WVF B;  3TO1 A;  1LW3 A;  2KIG A;  4WJ7 A;  2MFQ A;  3HW2 B;  3IVF A;  3WYF B;  1DBH A;  5I2M A;  3DXE A;  5LG4 B;  3U8Z A;  1NU2 A;  1WI1 A;  4HB0 B;  3N7C A;  1NTV A;  1U27 A;  2NBV A;  4DBB A;  1RRP B;  2CAY A;  3QIJ A;  1DYN A;  2EC1 A;  2X18 A;  1J19 A;  2ELB A;  3OAN A;  3X23 A;  4NY0 A;  2R2Y A;  3NW8 A;  4EMO A;  5HE3 A;  1U5G A;  3AU4 A;  1FOE A;  2PZ1 A;  3SV1 A;  3B77 A;  1V89 A;  3PZD A;  1XD4 A;  5JHH A;  1PFJ A;  1NTY A;  1W1D A;  3ML4 A;  3NWA A;  3CXB B;  2GUM A;  1B55 A;  2COA A;  1GC7 A;  4KHO A;  5JP4 A;  2RVB B;  1KZG A;  4PNK A;  3A8P A;  2HE7 A;  2D9Y A;  2YSZ A;  3DXD A;  1FHX A;  2I1K A;  5FI1 A;  2D4Q A;  2Q13 A;  5LOP B;  2N23 A;  2L1C A;  2LUL A;  4MK0 A;  2VSZ A;  4EKU A;  2KGX B;  4GN1 A;  3ODX A;  1H4R A;  1OMW A;  2YS1 A;  2Y8F A;  1EVH A;  2H7E A;  2Z0P A;  1EGX A;  3VIA A;  1XX0 A;  2CY4 A;  3WA0 A;  2NMB A;  4CSQ A;  3PVW A;  2KR0 A;  2DTC A;  2I5F A;  4ZRI A;  2W2X D;  1U29 A;  2DX5 A;  3TCA A;  4D6W A;  1UEF A;  2D2Q A;  2P0D A;  2DYQ A;  1WVH A;  4TKN A;  4A5K A;  5IRS A;  5D3V A;  2ELA A;  4HB2 B;  1E5W A;  4IFS A;  1GG3 A;  5C5B A;  4DX9 0;  3T06 A;  4HAW B; 
#chains in the Genus database with same CATH homology
 3D8E A;  4HDQ A;  2P0F A;  1KZ7 A;  5DH9 B;  1FHO A;  4A6F B;  2OTX A;  3FSS A;  4HAY B;  3TVV A;  5L81 A;  2R09 A;  1FB8 A;  1M7R A;  5DI9 B;  4IOY X;  1W1G A;  3V5W A;  2D11 A;  1PLS A;  2H7D A;  4MY6 A;  1DDM A;  1UNP A;  1I7A A;  2J0M A;  2UVM A;  5D3X A;  2LG1 A;  1SGH A;  2K2U A;  1U5E A;  3U7D A;  3ULC A;  2GJY A;  1MAI A;  2J59 M;  3SUZ A;  1MK7 B;  4D0N B;  5HE1 A;  3KSY A;  4DX8 A;  2DKP A;  3ODW A;  3BJI A;  3F0W A;  3QWM A;  2W2X C;  1K5D B;  4K81 A;  4CHJ A;  2MKR A;  1BWN A;  2VKI A;  4H8S A;  1UPQ A;  2L2I A;  1TXD A;  2UZS A;  5CLL B;  1GC6 A;  5CLQ B;  1MIX A;  5HE0 A;  2DKQ A;  1XOD A;  4P7I A;  4MT7 A;  2YVC A;  3GYO A;  2OQB A;  1IRS A;  1Z87 A;  4YON A;  1MIZ B;  1BAK A;  2R0D A;  3AJ4 A;  3G9W A;  4GMX B;  2YT0 A;  1W1H A;  2GCJ A;  1UNR A;  3O96 A;  1X05 A;  1ZM0 A;  5DHA B;  3KY9 A;  4C0A A;  4K2O A;  3PVL A;  3NSU A;  2LKO A;  4IAP A;  1V88 A;  1BTK A;  4DXA B;  4L6E A;  5DHF B;  3DXC A;  4HDO A;  5C16 A;  1V5P A;  3A8Q A;  3LJU X;  5EFX A;  2QKL A;  3QBV B;  2RLO A;  2D9Z A;  3UZT A;  5GOW B;  1UNQ A;  2COF A;  2UZR A;  3RCP A;  2HTH B;  3D8F A;  1I2H A;  3ZVR A;  2N0Y A;  3MPX A;  2K2J A;  4BBK A;  3TW1 A;  3ODO A;  4HB3 B;  5FI0 A;  1H10 A;  4EJN A;  5KQ1 A;  1P3R A;  1M7E A;  1X1F A;  3FM8 C;  1DDV A;  1WJ1 A;  4WSF A;  1J0W A;  2I5C A;  4GMV A;  1MPH A;  4KHA A;  2I1J A;  1ZC4 B;  2KUP A;  2BCJ A;  1K5G B;  3PSC A;  2AEH A;  2M38 A;  1QC6 A;  3SO6 A;  4A6H A;  2COD A;  4KAX B;  4F7G A;  5KCV A;  3SYX A;  4PQ0 A;  3ULB A;  5HE2 A;  4YL8 A;  1FGZ A;  2AL6 A;  2M14 A;  1DDW A;  2DN6 A;  2MDX A;  2RSG A;  3HQC A;  2DHK A;  5C6R A;  4HAU B;  2P0H A;  2QKM A;  2D10 A;  2CRF A;  1U5D A;  1V61 A;  2D9X A;  1WGQ A;  1ZC3 B;  1FGY A;  1WG7 A;  1XKE A;  2RUK B;  1XR0 B;  1Y5O A;  3KZ1 A;  3TFM A;  1NI2 A;  1WGU A;  4HB4 B;  3PG7 A;  3P6A A;  3P7Z A;  2COC A;  2YRY A;  1MKE A;  4CYE A;  5LON B;  4ZRK A;  2YS3 A;  2D9W A;  4HAT B;  5DIF B;  3M1I B;  4HAX B;  1LB1 A;  3D8D A;  4Y94 A;  3SNH A;  3PVU A;  2EJ8 A;  4GXB A;  1ZVR A;  1KI1 B;  2YS5 A;  1U2B A;  1N3H A;  1X86 A;  1DRO A;  2Y7B A;  1ZSQ A;  3GYP A;  5KQ4 A;  4CHM A;  3KRX A;  4XWX A;  5D27 A;  3AU5 A;  4HAV B;  1U5F A;  5D3W A;  2G35 A;  2YT1 A;  2ZPY A;  1AQC A;  2J0K A;  2JP2 A;  3ZDT A;  3PP2 A;  4TYZ A;  2EMS A;  2LOX A;  1EF1 A;  3MDB C;  2J0J A;  2LYD A;  4Z2M B;  2ROZ B;  3VOQ A;  2LOZ A;  2RGN B;  2DYN A;  1XCG A;  2DLW A;  2CY5 A;  5C79 A;  1SHC A;  4F7H A;  2FJL A;  1TJ6 A;  2GS0 A;  3HK0 A;  2DFK A;  4F7U P;  1MK9 B;  1V5U A;  2IFS A;  5D3Y A;  4Z2N A;  4HHV A;  4A6K A;  2E2X A;  1X11 A;  2KCJ A;  3CIK A;  2IYB A;  4NSW A;  5JHG A;  4B6H A;  5J3Q A;  1QQG A;  1UPR A;  2GCL A;  2ADZ A;  2DHI A;  4A6F A;  2Z0Q A;  2Y8G A;  1TQZ A;  2VRW B;  2W2W A;  4K2P A;  4KHB B;  1Q67 A;  3PEG A;  4K17 A;  1ISN A;  5JLJ B;  1FHW A;  2DA0 A;  4HAZ B;  2DHJ A;  4GZU A;  1X1G A;  4KVG B;  1OQN A;  1BTN A;  4GPT B;  5J3Y A;  5C5B B;  1PMS A;  2RNR B;  3A98 B;  1AWE A;  2D9V A;  2DX1 A;  3F5R A;  3FEH A;  1V5M A;  1EAZ A;  2K00 A;  3KRW A;  1P6S A;  1OY2 A;  1WJM A;  5J3T A;  2XQN M;  2Z0O A;  4ZRJ A;  1RJ2 A;  1FAO A;  2P8V A;  2EMT A;  2MWN B;  2ROV A;  2YF0 A;  2NZ8 B;  2V76 A;  1P5T A;  1Y19 B;  3BIN A;  3TO1 A;  4WVF B;  1LW3 A;  4WJ7 A;  2MFQ A;  3HW2 B;  3IVF A;  3WYF B;  1DBH A;  3DXE A;  3U8Z A;  1NU2 A;  1WI1 A;  4HB0 B;  3N7C A;  1NTV A;  1U27 A;  4DBB A;  1RRP B;  2CAY A;  3QIJ A;  1DYN A;  2EC1 A;  2X18 A;  1J19 A;  2ELB A;  3OAN A;  3X23 A;  4NY0 A;  4EMO A;  5HE3 A;  1U5G A;  3AU4 A;  1FOE A;  2PZ1 A;  3SV1 A;  1V89 A;  3PZD A;  1XD4 A;  5JHH A;  1PFJ A;  1NTY A;  1W1D A;  3ML4 A;  3CXB B;  1B55 A;  2COA A;  1GC7 A;  4KHO A;  5JP4 A;  2RVB B;  1KZG A;  4PNK A;  3A8P A;  2HE7 A;  2D9Y A;  2YSZ A;  3DXD A;  1FHX A;  2I1K A;  5FI1 A;  2D4Q A;  2Q13 A;  5LOP B;  2N23 A;  2L1C A;  2LUL A;  4MK0 A;  2VSZ A;  4EKU A;  2KGX B;  4GN1 A;  3ODX A;  1H4R A;  1OMW A;  2YS1 A;  2Y8F A;  1EVH A;  2H7E A;  2Z0P A;  1EGX A;  3VIA A;  1XX0 A;  2CY4 A;  3WA0 A;  2NMB A;  3PVW A;  2DTC A;  2I5F A;  4ZRI A;  2W2X D;  1U29 A;  2DX5 A;  3TCA A;  1UEF A;  2D2Q A;  2P0D A;  2DYQ A;  1WVH A;  4TKN A;  4A5K A;  5D3V A;  2ELA A;  4HB2 B;  1E5W A;  4IFS A;  1GG3 A;  5C5B A;  4DX9 0;  3T06 A;  4HAW B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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