4CA1A

Crystal structure of siah1 at 1.58 a resolution.
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
192
structure length
189
Chain Sequence
ANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Two High-Resolution Structures of the Human E3 Ubiquitin Ligase Siah1.
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords E3 UBIQUITIN-PROTEIN LIGASE SIAH1
total genus 42
structure length 189
sequence length 192
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2013-10-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 4ca1A02
3.30.40.10 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Zinc/RING finger domain, C3HC4 (zinc finger) 4ca1A01
2UZGA 2F42A 5H9MA 3HQHA 5D1LB 5H1TA 2FUUA 4AYCA 2RI7A 1WGMA 1FBVA 3PUQA 2CR2A 3RPGC 2QIZA 5TDWA 1G25A 1WEMA 1ZBDB 5C13A 3EB5A 2VP7A 3HCSA 4FIPA 5DKAA 3L11A 1Z2QA 4KG9A 3DQVR 4N3WA 2VPBA 3M62A 2FOOA 2YYRA 2ECVA 4YBMA 2KU3A 3M99A 4I7CA 2DX8A 1L0AA 1Z60A 1KZZA 4K8UA 2H0DA 5KH7A 3LQIA 2F1ZA 4FO9A 2ECGA 3SOWA 4V3LC 1WEVA 1N87A 2MA5A 3U5OA 2L80A 1CA9A 5FERA 2I50A 3N9MA 3O7AA 4GNDA 3SOUA 3N9NA 2C2VS 2MA6A 1JM7A 2A25A 2YU4A 1FLLA 2KE1A 4A0CD 4YSIA 5EYAF 2E6RA 4O1VA 1LB6A 4L58A 4LKAA 4P5OB 3V43A 5E1TA 4ZDTA 3O33A 2L0BA 2KGIA 3GL6A 4YBTA 4JJQA 2L75A 3HQMA 3U5PA 2LQ6A 4CA1A 2C2LA 2YHNA 1X4JA 2VNFA 5TABA 3MQSC 3O34A 3HTKC 4X3GA 3KV5A 2CSYA 4A4CA 5B76A 2ECIA 1IYMA 2K17A 4R2YA 5KH3A 4CCGX 2BAYA 2KGGA 4B7YC 4GNEA 3ZVZB 5KH9A 4C9ZA 1FLKA 2PNXA 1X4IA 3O37A 5LKUA 2F1YA 1JOCA 2KFTA 5H1VA 4YBSA 1Z6UA 2XXNA 2ZETC 3IHPA 5TDRA 2JRJA 2YSMA 5JG6A 1WENA 2FUIA 4LADB 3SHBA 4GHUA 3U5NA 1LDKC 2HDPA 2G43A 1WEEA 2MNYA 2Y43A 2PUYA 4GB0A 3HSVA 3N9LA 2F6JA 2XB1A 2ECWA 3HQIA 2LRIC 5B78A 2KWJA 1MM2A 5B75A 2KIZA 2CSZA 4GJHA 1D0JA 1VFYA 2LGVA 2JMJA 4QF2A 3ZJBA 1VYXA 1LB5A 1FP0A 2EODA 4UP0A 2RSDA 4Q6FA 3ZPV1 4IC2A 2G6QA 2OXQC 2AN6A 3KQIA 5LCWB 4GWMA 2KWNA 1CZZA 3IVBA 2VJFB 5B8DA 1WEPA 3T6RA 3C6WA 4AVXA 1F62A 5J3XA 2XEUA 2LN0A 4NN2A 3PURA 1WILA 1X4UA 4YADA 3KNVA 4B86C 2F6NA 3L1XA 4A4BA 1VD4A 4A49A 1WFKA 3FL2A 4GNGA 3N9PA 2YSJA 2LGGA 1YY6A 4I7DA 1D0AA 2FOJA 2CKLB 3QZVA 2K1JA 2M6MA 4S3OB 3EB6A 2QICA 5LKZA 2IDAA 3MHSA 1ZMSA 2YQLA 1T1HA 3MQRA 2MNZA 3C5KA 3O35A 4XI1A 4M4EA 4GWNA 4ZQLA 2JMIA 1D00A 1CA4A 3HCUA 4L7XA 4ZUXU 1MM3A 4PTBA 1HYIA 1K2FA 1U6GB 1WE9A 2YREA 1BORA 1D01A 5D1KB 4BHWA 4WZ3B 2EGPA 4LLBA 5AITA 2L43A 2VPEA 3U5MA 4R7EA 2E6SA 4MVTA 2HYED 1F3VB 2LXPC 5I3LA 3LQHA 2KREA 2LDRA 5C11A 3ASLA 2ECJA 2LXHC 4WA6A 1DVPA 3ZYQA 2KYUA 1CHCA 2YURA 2YHOA 5D1MB 3M63A 4AP4A 2YT5A 4WZ2A 2KWKA 1WEOA 3ZTGA 3DPLR 2MIQA 2VJFA 3RPGB 2KR4A 3LQJA 2LV9A 2ECNA 4GNFA 5H1UA 3N9OA 2D8SA 3L1ZB 2MD7B 4R8PK 3O70A 5FB1A 4F52B 4PPEA 2MUMA 3HU6A 2NAAA 2Y1NA 3VK6A 4WZ0A 2VJEB 2JMDA 4QF3A 5DINA 2GKWA 4TKPB 5G0FA 2M3HA 5G05B 4IC3A 2CKLA 3SOXA 1WIMA 2CT2A 1XWHA 5FB0A 5B77A 5B79A 1V87A 4AYCB 3ZVYA 3PHDA 5AIUA 3HQLA 2EA6A 4YC9A 2MD8C 3N9QA 3LRQA 3I2DA 2Y1MA 1RF3A 3O36A 5LKTA 2M85A 2KWOA 3NG2A 1QSCA 3KV6A 3IVQA 3RTRB 4YABA 2QJ0A 4Z8MA 2YQMA 1YZEA 2L5UA 2G45A 5G04B 4BBQA 2YW8A 2H0DB 4FJCA 2LGKA 2M1RA 4YATA 3HCTA 4AUQB 3ZNIA 1WEQA 2ECTA 2LGLA 2VPDA 4I7BA 1WESA 5TRBA 3T7LA 4UP5A 4S3OC 4W4UA 2F1WA 2VPGA 1E4UA 1HYJA 3MHHA 1JM7B 5FEYA 4N4FA 3GV4A 5TBNA 4LJNA 4FK5A 2YUCA 4UI9B 1LB4A 2K4DA 2F1XA 4O64A 2FOPA 4LK9A 2FSAA 1LDJB 3ZPVE 1WEWA 2VJEA 4YAXA 4MSXA 4V3KC 1CZYA 2K16A 1WEUA 5LKXA 2MT5A 1RMDA 3IVVA
chains in the Genus database with same CATH superfamily
2UZGA 2F42A 5H9MA 3HQHA 5D1LB 5H1TA 2FUUA 4AYCA 2RI7A 1WGMA 1FBVA 2EXUA 3PUQA 2CR2A 3RPGC 2QIZA 5TDWA 1G25A 5SVXA 1WEMA 1ZBDB 5C13A 5K3QA 3EB5A 3T9KA 3DWDA 2VP7A 3HCSA 4FIPA 5DKAA 3L11A 3FAOA 4Z0RA 2L7PA 3H7HA 1Z2QA 4KG9A 3DQVR 4N3WA 2VPBA 2FOOA 2YYRA 3M62A 2ECVA 2FD4A 4YBMA 2KU3A 3M99A 4I7CA 2DX8A 1L0AA 1Z60A 1KZZA 4K8UA 3PLWA 2H0DA 5KH7A 3LQIA 2F1ZA 4FO9A 2ECGA 3SOWA 4V3LC 1WEVA 1N87A 2MA5A 5SVYA 3U5OA 2L80A 1CA9A 2E61A 5FERA 2I50A 3FANA 3N9MA 3O7AA 4GNDA 3SOUA 2CSVA 3M7KA 3N9NA 2C2VS 2MA6A 1JM7A 2A25A 2YU4A 1FLLA 2KE1A 4A0CD 4YSIA 5EYAF 2E6RA 4O1VA 1LB6A 4L58A 4LKAA 3FM8C 4P5OB 3V43A 5E1TA 4ZDTA 3O33A 5SVIB 4O62A 2L0BA 2KGIA 3GL6A 4YBTA 3SUBA 4JJQA 2L75A 3HQMA 3U5PA 2LQ6A 4CA1A 2C2LA 2YHNA 1X4JA 2VNFA 3DDTA 5TABA 3MQSC 3O34A 3HTKC 4X3GA 3KV5A 2CSYA 4A4CA 5B76A 2ECIA 1IYMA 2K17A 4R2YA 5KH3A 4CCGX 2BAYA 2KGGA 2XP0A 4B7YC 4GNEA 3ZVZB 5KH9A 4C9ZA 1FLKA 2PNXA 1X4IA 3O37A 5LKUA 2F1YA 1JOCA 2KFTA 5H1VA 4YBSA 1Z6UA 2XXNA 2ZETC 3IHPA 5TDRA 2JRJA 2YSMA 5JG6A 1WENA 2FUIA 4H9DA 4LADB 2KKXA 3SHBA 4GHUA 3LVRE 3U5NA 1LDKC 2HDPA 2G43A 1WEEA 2MNYA 2Y43A 2PUYA 1MBMA 4GB0A 3HSVA 3N9LA 2F6JA 2XB1A 2ECWA 3HQIA 2LRIC 2CRRA 5B78A 2KWJA 2JM3A 1MM2A 3KDEC 5B75A 2KIZA 3O47A 2CSZA 4GJHA 1D0JA 1VFYA 2LGVA 2JMJA 4QF2A 3ZJBA 1VYXA 3LVQE 1LB5A 4Z0OA 1FP0A 2DJAA 2EODA 4UP0A 2RSDA 4Q6FA 3ZPV1 4IC2A 3E2DA 2G6QA 2OXQC 2AN6A 3KQIA 5LCWB 5SVIA 4GWMA 2KWNA 1CZZA 3IVBA 2VJFB 5B8DA 1WEPA 3T6RA 3C6WA 4AVXA 1F62A 5J3XA 2XEUA 2LN0A 4NN2A 3PURA 1WILA 1X4UA 4YADA 3KNVA 4B86C 2F6NA 2XOZA 3L1XA 2P57A 4A4BA 1VD4A 2FFWA 4A49A 4OGCA 1WFKA 2RR4A 1DCQA 3FL2A 4GNGA 3N9PA 2YSJA 2LGGA 1YY6A 4I7DA 2IQJA 1D0AA 2FOJA 2CKLB 3QZVA 2DSMA 2XOCA 2K1JA 2M6MA 4S3OB 3EB6A 2QICA 5LKZA 2IDAA 3MHSA 3FJUB 1ZMSA 2YQLA 1T1HA 3MQRA 2MNZA 3C5KA 3O35A 3Q1DA 4XI1A 3LJUX 4M4EA 4GWNA 4OGEA 4ZQLA 2JMIA 1D00A 1CA4A 3HCUA 4L7XA 4ZUXU 1MM3A 4PTBA 1HYIA 1K2FA 2CRWA 1U6GB 1WE9A 2YREA 2D8UA 1BORA 1D01A 5D1KB 4BHWA 4WZ3B 2EGPA 4LLBA 5AITA 2L43A 2VPEA 3U5MA 4R7EA 2E6SA 4MVTA 2HYED 1F3VB 2LXPC 5I3LA 3LQHA 2KREA 2LDRA 5C11A 3ASLA 2ECJA 2LXHC 4WA6A 1DVPA 3ZYQA 2KYUA 1CHCA 2YURA 2YHOA 5D1MB 3M63A 4AP4A 2YT5A 4WZ2A 2KWKA 1WEOA 3ZTGA 3DPLR 2MIQA 2VJFA 3RPGB 2KR4A 3LQJA 2LV9A 2ECNA 4GNFA 5H1UA 3N9OA 2D8SA 3L1ZB 3LDYA 2MD7B 2LAUA 4R8PK 3O70A 5FB1A 4F52B 4PPEA 2MUMA 3HU6A 2NAAA 2Y1NA 3VK6A 4WZ0A 2VJEB 2JMDA 4QF3A 5DINA 2GKWA 4TKPB 5G0FA 2M3HA 2M13A 5G05B 4IC3A 2CKLA 3SOXA 1WIMA 2YVRA 2CT2A 1XWHA 5FB0A 3JUEA 2KKYA 5B77A 5B79A 2EGMA 1V87A 4AYCB 3ZVYA 3PHDA 5AIUA 3HQLA 2EA6A 4YC9A 2MD8C 3N9QA 3LRQA 3I2DA 2Y1MA 1RF3A 3O36A 5LKTA 2M85A 2KWOA 3NG2A 2B0OE 1QSCA 3KV6A 3IVQA 3RTRB 4YABA 2QJ0A 4Z8MA 2YQMA 1YZEA 2JUNA 2L5UA 2G45A 5G04B 4BBQA 2YW8A 2H0DB 4FJCA 2LGKA 2M1RA 4YATA 3HCTA 4AUQB 3ZNIA 1WEQA 2ECTA 2LGLA 2VPDA 3MDBC 4I7BA 1WESA 3FEHA 5TRBA 3T7LA 4UP5A 4S3OC 4W4UA 2F1WA 2VPGA 1E4UA 1HYJA 3MHHA 1JM7B 2OWAA 5FEYA 2MKEA 4N4FA 3GV4A 5TBNA 4LJNA 4FK5A 4F1PA 2YUCA 4UI9B 1LB4A 2K4DA 2F1XA 4O64A 2FOPA 4LK9A 4QQ4A 2FSAA 2XOYA 2CONA 1LDJB 3ZPVE 1WEWA 2VJEA 4YAXA 4MSXA 4V3KC 1CZYA 2K16A 1WEUA 5LKXA 2MT5A 1RMDA 3IVVA
chains in the Genus database with same CATH topology
2UZGA 2F42A 5H9MA 3HQHA 5D1LB 5H1TA 2FUUA 4AYCA 2RI7A 1WGMA 1FBVA 3PUQA 2CR2A 3RPGC 2QIZA 5TDWA 1G25A 1WEMA 1ZBDB 5C13A 3EB5A 2VP7A 3HCSA 4FIPA 5DKAA 3L11A 1Z2QA 4KG9A 3DQVR 4N3WA 2VPBA 3M62A 2FOOA 2YYRA 2ECVA 4YBMA 2KU3A 3M99A 4I7CA 2DX8A 1L0AA 1Z60A 1KZZA 4K8UA 2H0DA 5KH7A 3LQIA 2F1ZA 4FO9A 2ECGA 3SOWA 4V3LC 1WEVA 1N87A 2MA5A 3U5OA 2L80A 1CA9A 5FERA 2I50A 3N9MA 3O7AA 4GNDA 3SOUA 3N9NA 2C2VS 2MA6A 1JM7A 2A25A 2YU4A 1FLLA 2KE1A 4A0CD 4YSIA 5EYAF 2E6RA 4O1VA 1LB6A 4L58A 4LKAA 4P5OB 3V43A 5E1TA 4ZDTA 3O33A 2L0BA 2KGIA 3GL6A 4YBTA 4JJQA 2L75A 3HQMA 3U5PA 2LQ6A 4CA1A 2C2LA 2YHNA 1X4JA 2VNFA 5TABA 3MQSC 3O34A 3HTKC 4X3GA 3KV5A 2CSYA 4A4CA 5B76A 2ECIA 1IYMA 2K17A 4R2YA 5KH3A 4CCGX 2BAYA 2KGGA 4B7YC 4GNEA 3ZVZB 5KH9A 4C9ZA 1FLKA 2PNXA 1X4IA 3O37A 5LKUA 2F1YA 1JOCA 2KFTA 5H1VA 4YBSA 1Z6UA 2XXNA 2ZETC 3IHPA 5TDRA 2JRJA 2YSMA 5JG6A 1WENA 2FUIA 4LADB 3SHBA 4GHUA 3U5NA 1LDKC 2HDPA 2G43A 1WEEA 2MNYA 2Y43A 2PUYA 4GB0A 3HSVA 3N9LA 2F6JA 2XB1A 2ECWA 3HQIA 2LRIC 5B78A 2KWJA 1MM2A 5B75A 2KIZA 2CSZA 4GJHA 1D0JA 1VFYA 2LGVA 2JMJA 4QF2A 3ZJBA 1VYXA 1LB5A 1FP0A 2EODA 4UP0A 2RSDA 4Q6FA 3ZPV1 4IC2A 2G6QA 2OXQC 2AN6A 3KQIA 5LCWB 4GWMA 2KWNA 1CZZA 3IVBA 2VJFB 5B8DA 1WEPA 3T6RA 3C6WA 4AVXA 1F62A 5J3XA 2XEUA 2LN0A 4NN2A 3PURA 1WILA 1X4UA 4YADA 3KNVA 4B86C 2F6NA 3L1XA 4A4BA 1VD4A 4A49A 1WFKA 3FL2A 4GNGA 3N9PA 2YSJA 2LGGA 1YY6A 4I7DA 1D0AA 2FOJA 2CKLB 3QZVA 2K1JA 2M6MA 4S3OB 3EB6A 2QICA 5LKZA 2IDAA 3MHSA 1ZMSA 2YQLA 1T1HA 3MQRA 2MNZA 3C5KA 3O35A 4XI1A 4M4EA 4GWNA 4ZQLA 2JMIA 1D00A 1CA4A 3HCUA 4L7XA 4ZUXU 1MM3A 4PTBA 1HYIA 1K2FA 1U6GB 1WE9A 2YREA 1BORA 1D01A 5D1KB 4BHWA 4WZ3B 2EGPA 4LLBA 5AITA 2L43A 2VPEA 3U5MA 4R7EA 2E6SA 4MVTA 2HYED 1F3VB 2LXPC 5I3LA 3LQHA 2KREA 2LDRA 5C11A 3ASLA 2ECJA 2LXHC 4WA6A 1DVPA 3ZYQA 2KYUA 1CHCA 2YURA 2YHOA 5D1MB 3M63A 4AP4A 2YT5A 4WZ2A 2KWKA 1WEOA 3ZTGA 3DPLR 2MIQA 2VJFA 3RPGB 2KR4A 3LQJA 2LV9A 2ECNA 4GNFA 5H1UA 3N9OA 2D8SA 3L1ZB 2MD7B 4R8PK 3O70A 5FB1A 4F52B 4PPEA 2MUMA 3HU6A 2NAAA 2Y1NA 3VK6A 4WZ0A 2VJEB 2JMDA 4QF3A 5DINA 2GKWA 4TKPB 5G0FA 2M3HA 5G05B 4IC3A 2CKLA 3SOXA 1WIMA 2CT2A 1XWHA 5FB0A 5B77A 5B79A 1V87A 4AYCB 3ZVYA 3PHDA 5AIUA 3HQLA 2EA6A 4YC9A 2MD8C 3N9QA 3LRQA 3I2DA 2Y1MA 1RF3A 3O36A 5LKTA 2M85A 2KWOA 3NG2A 1QSCA 3KV6A 3IVQA 3RTRB 4YABA 2QJ0A 4Z8MA 2YQMA 1YZEA 2L5UA 2G45A 5G04B 4BBQA 2YW8A 2H0DB 4FJCA 2LGKA 2M1RA 4YATA 3HCTA 4AUQB 3ZNIA 1WEQA 2ECTA 2LGLA 2VPDA 4I7BA 1WESA 5TRBA 3T7LA 4UP5A 4S3OC 4W4UA 2F1WA 2VPGA 1E4UA 1HYJA 3MHHA 1JM7B 5FEYA 4N4FA 3GV4A 5TBNA 4LJNA 4FK5A 2YUCA 4UI9B 1LB4A 2K4DA 2F1XA 4O64A 2FOPA 4LK9A 2FSAA 1LDJB 3ZPVE 1WEWA 2VJEA 4YAXA 4MSXA 4V3KC 1CZYA 2K16A 1WEUA 5LKXA 2MT5A 1RMDA 3IVVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2UZG A;  2F42 A;  5H9M A;  3HQH A;  5D1L B;  5H1T A;  2FUU A;  4AYC A;  2RI7 A;  1WGM A;  1FBV A;  3PUQ A;  2CR2 A;  3RPG C;  2QIZ A;  5TDW A;  1G25 A;  1WEM A;  1ZBD B;  5C13 A;  3EB5 A;  2VP7 A;  3HCS A;  4FIP A;  5DKA A;  3L11 A;  1Z2Q A;  4KG9 A;  3DQV R;  4N3W A;  2VPB A;  3M62 A;  2FOO A;  2YYR A;  2ECV A;  4YBM A;  2KU3 A;  3M99 A;  4I7C A;  2DX8 A;  1L0A A;  1Z60 A;  1KZZ A;  4K8U A;  2H0D A;  5KH7 A;  3LQI A;  2F1Z A;  4FO9 A;  2ECG A;  3SOW A;  4V3L C;  1WEV A;  1N87 A;  2MA5 A;  3U5O A;  2L80 A;  1CA9 A;  5FER A;  2I50 A;  3N9M A;  3O7A A;  4GND A;  3SOU A;  3N9N A;  2C2V S;  2MA6 A;  1JM7 A;  2A25 A;  2YU4 A;  1FLL A;  2KE1 A;  4A0C D;  4YSI A;  5EYA F;  2E6R A;  4O1V A;  1LB6 A;  4L58 A;  4LKA A;  4P5O B;  3V43 A;  5E1T A;  4ZDT A;  3O33 A;  2L0B A;  2KGI A;  3GL6 A;  4YBT A;  4JJQ A;  2L75 A;  3HQM A;  3U5P A;  2LQ6 A;  4CA1 A;  2C2L A;  2YHN A;  1X4J A;  2VNF A;  5TAB A;  3MQS C;  3O34 A;  3HTK C;  4X3G A;  3KV5 A;  2CSY A;  4A4C A;  5B76 A;  2ECI A;  1IYM A;  2K17 A;  4R2Y A;  5KH3 A;  4CCG X;  2BAY A;  2KGG A;  4B7Y C;  4GNE A;  3ZVZ B;  5KH9 A;  4C9Z A;  1FLK A;  2PNX A;  1X4I A;  3O37 A;  5LKU A;  2F1Y A;  1JOC A;  2KFT A;  5H1V A;  4YBS A;  1Z6U A;  2XXN A;  2ZET C;  3IHP A;  5TDR A;  2JRJ A;  2YSM A;  5JG6 A;  1WEN A;  2FUI A;  4LAD B;  3SHB A;  4GHU A;  3U5N A;  1LDK C;  2HDP A;  2G43 A;  1WEE A;  2MNY A;  2Y43 A;  2PUY A;  4GB0 A;  3HSV A;  3N9L A;  2F6J A;  2XB1 A;  2ECW A;  3HQI A;  2LRI C;  5B78 A;  2KWJ A;  1MM2 A;  5B75 A;  2KIZ A;  2CSZ A;  4GJH A;  1D0J A;  1VFY A;  2LGV A;  2JMJ A;  4QF2 A;  3ZJB A;  1VYX A;  1LB5 A;  1FP0 A;  2EOD A;  4UP0 A;  2RSD A;  4Q6F A;  3ZPV 1;  4IC2 A;  2G6Q A;  2OXQ C;  2AN6 A;  3KQI A;  5LCW B;  4GWM A;  2KWN A;  1CZZ A;  3IVB A;  2VJF B;  5B8D A;  1WEP A;  3T6R A;  3C6W A;  4AVX A;  1F62 A;  5J3X A;  2XEU A;  2LN0 A;  4NN2 A;  3PUR A;  1WIL A;  1X4U A;  4YAD A;  3KNV A;  4B86 C;  2F6N A;  3L1X A;  4A4B A;  1VD4 A;  4A49 A;  1WFK A;  3FL2 A;  4GNG A;  3N9P A;  2YSJ A;  2LGG A;  1YY6 A;  4I7D A;  1D0A A;  2FOJ A;  2CKL B;  3QZV A;  2K1J A;  2M6M A;  4S3O B;  3EB6 A;  2QIC A;  5LKZ A;  2IDA A;  3MHS A;  1ZMS A;  2YQL A;  1T1H A;  3MQR A;  2MNZ A;  3C5K A;  3O35 A;  4XI1 A;  4M4E A;  4GWN A;  4ZQL A;  2JMI A;  1D00 A;  1CA4 A;  3HCU A;  4L7X A;  4ZUX U;  1MM3 A;  4PTB A;  1HYI A;  1K2F A;  1U6G B;  1WE9 A;  2YRE A;  1BOR A;  1D01 A;  5D1K B;  4BHW A;  4WZ3 B;  2EGP A;  4LLB A;  5AIT A;  2L43 A;  2VPE A;  3U5M A;  4R7E A;  2E6S A;  4MVT A;  2HYE D;  1F3V B;  2LXP C;  5I3L A;  3LQH A;  2KRE A;  2LDR A;  5C11 A;  3ASL A;  2ECJ A;  2LXH C;  4WA6 A;  1DVP A;  3ZYQ A;  2KYU A;  1CHC A;  2YUR A;  2YHO A;  5D1M B;  3M63 A;  4AP4 A;  2YT5 A;  4WZ2 A;  2KWK A;  1WEO A;  3ZTG A;  3DPL R;  2MIQ A;  2VJF A;  3RPG B;  2KR4 A;  3LQJ A;  2LV9 A;  2ECN A;  4GNF A;  5H1U A;  3N9O A;  2D8S A;  3L1Z B;  2MD7 B;  4R8P K;  3O70 A;  5FB1 A;  4F52 B;  4PPE A;  2MUM A;  3HU6 A;  2NAA A;  2Y1N A;  3VK6 A;  4WZ0 A;  2VJE B;  2JMD A;  4QF3 A;  5DIN A;  2GKW A;  4TKP B;  5G0F A;  2M3H A;  5G05 B;  4IC3 A;  2CKL A;  3SOX A;  1WIM A;  2CT2 A;  1XWH A;  5FB0 A;  5B77 A;  5B79 A;  1V87 A;  4AYC B;  3ZVY A;  3PHD A;  5AIU A;  3HQL A;  2EA6 A;  4YC9 A;  2MD8 C;  3N9Q A;  3LRQ A;  3I2D A;  2Y1M A;  1RF3 A;  3O36 A;  5LKT A;  2M85 A;  2KWO A;  3NG2 A;  1QSC A;  3KV6 A;  3IVQ A;  3RTR B;  4YAB A;  2QJ0 A;  4Z8M A;  2YQM A;  1YZE A;  2L5U A;  2G45 A;  5G04 B;  4BBQ A;  2YW8 A;  2H0D B;  4FJC A;  2LGK A;  2M1R A;  4YAT A;  3HCT A;  4AUQ B;  3ZNI A;  1WEQ A;  2ECT A;  2LGL A;  2VPD A;  4I7B A;  1WES A;  5TRB A;  3T7L A;  4UP5 A;  4S3O C;  4W4U A;  2F1W A;  2VPG A;  1E4U A;  1HYJ A;  3MHH A;  1JM7 B;  5FEY A;  4N4F A;  3GV4 A;  5TBN A;  4LJN A;  4FK5 A;  2YUC A;  4UI9 B;  1LB4 A;  2K4D A;  2F1X A;  4O64 A;  2FOP A;  4LK9 A;  2FSA A;  1LDJ B;  3ZPV E;  1WEW A;  2VJE A;  4YAX A;  4MSX A;  4V3K C;  1CZY A;  2K16 A;  1WEU A;  5LKX A;  2MT5 A;  1RMD A;  3IVV A; 
#chains in the Genus database with same CATH topology
 2UZG A;  2F42 A;  5H9M A;  3HQH A;  5D1L B;  5H1T A;  2FUU A;  4AYC A;  2RI7 A;  1WGM A;  1FBV A;  2EXU A;  3PUQ A;  2CR2 A;  3RPG C;  2QIZ A;  5TDW A;  1G25 A;  5SVX A;  1WEM A;  1ZBD B;  5C13 A;  5K3Q A;  3EB5 A;  3T9K A;  3DWD A;  2VP7 A;  3HCS A;  4FIP A;  5DKA A;  3L11 A;  3FAO A;  4Z0R A;  2L7P A;  3H7H A;  1Z2Q A;  4KG9 A;  3DQV R;  4N3W A;  2VPB A;  2FOO A;  2YYR A;  3M62 A;  2ECV A;  2FD4 A;  4YBM A;  2KU3 A;  3M99 A;  4I7C A;  2DX8 A;  1L0A A;  1Z60 A;  1KZZ A;  4K8U A;  3PLW A;  2H0D A;  5KH7 A;  3LQI A;  2F1Z A;  4FO9 A;  2ECG A;  3SOW A;  4V3L C;  1WEV A;  1N87 A;  2MA5 A;  5SVY A;  3U5O A;  2L80 A;  1CA9 A;  2E61 A;  5FER A;  2I50 A;  3FAN A;  3N9M A;  3O7A A;  4GND A;  3SOU A;  2CSV A;  3M7K A;  3N9N A;  2C2V S;  2MA6 A;  1JM7 A;  2A25 A;  2YU4 A;  1FLL A;  2KE1 A;  4A0C D;  4YSI A;  5EYA F;  2E6R A;  4O1V A;  1LB6 A;  4L58 A;  4LKA A;  3FM8 C;  4P5O B;  3V43 A;  5E1T A;  4ZDT A;  3O33 A;  5SVI B;  4O62 A;  2L0B A;  2KGI A;  3GL6 A;  4YBT A;  3SUB A;  4JJQ A;  2L75 A;  3HQM A;  3U5P A;  2LQ6 A;  4CA1 A;  2C2L A;  2YHN A;  1X4J A;  2VNF A;  3DDT A;  5TAB A;  3MQS C;  3O34 A;  3HTK C;  4X3G A;  3KV5 A;  2CSY A;  4A4C A;  5B76 A;  2ECI A;  1IYM A;  2K17 A;  4R2Y A;  5KH3 A;  4CCG X;  2BAY A;  2KGG A;  2XP0 A;  4B7Y C;  4GNE A;  3ZVZ B;  5KH9 A;  4C9Z A;  1FLK A;  2PNX A;  1X4I A;  3O37 A;  5LKU A;  2F1Y A;  1JOC A;  2KFT A;  5H1V A;  4YBS A;  1Z6U A;  2XXN A;  2ZET C;  3IHP A;  5TDR A;  2JRJ A;  2YSM A;  5JG6 A;  1WEN A;  2FUI A;  4H9D A;  4LAD B;  2KKX A;  3SHB A;  4GHU A;  3LVR E;  3U5N A;  1LDK C;  2HDP A;  2G43 A;  1WEE A;  2MNY A;  2Y43 A;  2PUY A;  1MBM A;  4GB0 A;  3HSV A;  3N9L A;  2F6J A;  2XB1 A;  2ECW A;  3HQI A;  2LRI C;  2CRR A;  5B78 A;  2KWJ A;  2JM3 A;  1MM2 A;  3KDE C;  5B75 A;  2KIZ A;  3O47 A;  2CSZ A;  4GJH A;  1D0J A;  1VFY A;  2LGV A;  2JMJ A;  4QF2 A;  3ZJB A;  1VYX A;  3LVQ E;  1LB5 A;  4Z0O A;  1FP0 A;  2DJA A;  2EOD A;  4UP0 A;  2RSD A;  4Q6F A;  3ZPV 1;  4IC2 A;  3E2D A;  2G6Q A;  2OXQ C;  2AN6 A;  3KQI A;  5LCW B;  5SVI A;  4GWM A;  2KWN A;  1CZZ A;  3IVB A;  2VJF B;  5B8D A;  1WEP A;  3T6R A;  3C6W A;  4AVX A;  1F62 A;  5J3X A;  2XEU A;  2LN0 A;  4NN2 A;  3PUR A;  1WIL A;  1X4U A;  4YAD A;  3KNV A;  4B86 C;  2F6N A;  2XOZ A;  3L1X A;  2P57 A;  4A4B A;  1VD4 A;  2FFW A;  4A49 A;  4OGC A;  1WFK A;  2RR4 A;  1DCQ A;  3FL2 A;  4GNG A;  3N9P A;  2YSJ A;  2LGG A;  1YY6 A;  4I7D A;  2IQJ A;  1D0A A;  2FOJ A;  2CKL B;  3QZV A;  2DSM A;  2XOC A;  2K1J A;  2M6M A;  4S3O B;  3EB6 A;  2QIC A;  5LKZ A;  2IDA A;  3MHS A;  3FJU B;  1ZMS A;  2YQL A;  1T1H A;  3MQR A;  2MNZ A;  3C5K A;  3O35 A;  3Q1D A;  4XI1 A;  3LJU X;  4M4E A;  4GWN A;  4OGE A;  4ZQL A;  2JMI A;  1D00 A;  1CA4 A;  3HCU A;  4L7X A;  4ZUX U;  1MM3 A;  4PTB A;  1HYI A;  1K2F A;  2CRW A;  1U6G B;  1WE9 A;  2YRE A;  2D8U A;  1BOR A;  1D01 A;  5D1K B;  4BHW A;  4WZ3 B;  2EGP A;  4LLB A;  5AIT A;  2L43 A;  2VPE A;  3U5M A;  4R7E A;  2E6S A;  4MVT A;  2HYE D;  1F3V B;  2LXP C;  5I3L A;  3LQH A;  2KRE A;  2LDR A;  5C11 A;  3ASL A;  2ECJ A;  2LXH C;  4WA6 A;  1DVP A;  3ZYQ A;  2KYU A;  1CHC A;  2YUR A;  2YHO A;  5D1M B;  3M63 A;  4AP4 A;  2YT5 A;  4WZ2 A;  2KWK A;  1WEO A;  3ZTG A;  3DPL R;  2MIQ A;  2VJF A;  3RPG B;  2KR4 A;  3LQJ A;  2LV9 A;  2ECN A;  4GNF A;  5H1U A;  3N9O A;  2D8S A;  3L1Z B;  3LDY A;  2MD7 B;  2LAU A;  4R8P K;  3O70 A;  5FB1 A;  4F52 B;  4PPE A;  2MUM A;  3HU6 A;  2NAA A;  2Y1N A;  3VK6 A;  4WZ0 A;  2VJE B;  2JMD A;  4QF3 A;  5DIN A;  2GKW A;  4TKP B;  5G0F A;  2M3H A;  2M13 A;  5G05 B;  4IC3 A;  2CKL A;  3SOX A;  1WIM A;  2YVR A;  2CT2 A;  1XWH A;  5FB0 A;  3JUE A;  2KKY A;  5B77 A;  5B79 A;  2EGM A;  1V87 A;  4AYC B;  3ZVY A;  3PHD A;  5AIU A;  3HQL A;  2EA6 A;  4YC9 A;  2MD8 C;  3N9Q A;  3LRQ A;  3I2D A;  2Y1M A;  1RF3 A;  3O36 A;  5LKT A;  2M85 A;  2KWO A;  3NG2 A;  2B0O E;  1QSC A;  3KV6 A;  3IVQ A;  3RTR B;  4YAB A;  2QJ0 A;  4Z8M A;  2YQM A;  1YZE A;  2JUN A;  2L5U A;  2G45 A;  5G04 B;  4BBQ A;  2YW8 A;  2H0D B;  4FJC A;  2LGK A;  2M1R A;  4YAT A;  3HCT A;  4AUQ B;  3ZNI A;  1WEQ A;  2ECT A;  2LGL A;  2VPD A;  3MDB C;  4I7B A;  1WES A;  3FEH A;  5TRB A;  3T7L A;  4UP5 A;  4S3O C;  4W4U A;  2F1W A;  2VPG A;  1E4U A;  1HYJ A;  3MHH A;  1JM7 B;  2OWA A;  5FEY A;  2MKE A;  4N4F A;  3GV4 A;  5TBN A;  4LJN A;  4FK5 A;  4F1P A;  2YUC A;  4UI9 B;  1LB4 A;  2K4D A;  2F1X A;  4O64 A;  2FOP A;  4LK9 A;  4QQ4 A;  2FSA A;  2XOY A;  2CON A;  1LDJ B;  3ZPV E;  1WEW A;  2VJE A;  4YAX A;  4MSX A;  4V3K C;  1CZY A;  2K16 A;  1WEU A;  5LKX A;  2MT5 A;  1RMD A;  3IVV A; 
#chains in the Genus database with same CATH homology
 2UZG A;  2F42 A;  5H9M A;  3HQH A;  5D1L B;  5H1T A;  2FUU A;  4AYC A;  2RI7 A;  1WGM A;  1FBV A;  3PUQ A;  2CR2 A;  3RPG C;  2QIZ A;  5TDW A;  1G25 A;  1WEM A;  1ZBD B;  5C13 A;  3EB5 A;  2VP7 A;  3HCS A;  4FIP A;  5DKA A;  3L11 A;  1Z2Q A;  4KG9 A;  3DQV R;  4N3W A;  2VPB A;  3M62 A;  2FOO A;  2YYR A;  2ECV A;  4YBM A;  2KU3 A;  3M99 A;  4I7C A;  2DX8 A;  1L0A A;  1Z60 A;  1KZZ A;  4K8U A;  2H0D A;  5KH7 A;  3LQI A;  2F1Z A;  4FO9 A;  2ECG A;  3SOW A;  4V3L C;  1WEV A;  1N87 A;  2MA5 A;  3U5O A;  2L80 A;  1CA9 A;  5FER A;  2I50 A;  3N9M A;  3O7A A;  4GND A;  3SOU A;  3N9N A;  2C2V S;  2MA6 A;  1JM7 A;  2A25 A;  2YU4 A;  1FLL A;  2KE1 A;  4A0C D;  4YSI A;  5EYA F;  2E6R A;  4O1V A;  1LB6 A;  4L58 A;  4LKA A;  4P5O B;  3V43 A;  5E1T A;  4ZDT A;  3O33 A;  2L0B A;  2KGI A;  3GL6 A;  4YBT A;  4JJQ A;  2L75 A;  3HQM A;  3U5P A;  2LQ6 A;  4CA1 A;  2C2L A;  2YHN A;  1X4J A;  2VNF A;  5TAB A;  3MQS C;  3O34 A;  3HTK C;  4X3G A;  3KV5 A;  2CSY A;  4A4C A;  5B76 A;  2ECI A;  1IYM A;  2K17 A;  4R2Y A;  5KH3 A;  4CCG X;  2BAY A;  2KGG A;  4B7Y C;  4GNE A;  3ZVZ B;  5KH9 A;  4C9Z A;  1FLK A;  2PNX A;  1X4I A;  3O37 A;  5LKU A;  2F1Y A;  1JOC A;  2KFT A;  5H1V A;  4YBS A;  1Z6U A;  2XXN A;  2ZET C;  3IHP A;  5TDR A;  2JRJ A;  2YSM A;  5JG6 A;  1WEN A;  2FUI A;  4LAD B;  3SHB A;  4GHU A;  3U5N A;  1LDK C;  2HDP A;  2G43 A;  1WEE A;  2MNY A;  2Y43 A;  2PUY A;  4GB0 A;  3HSV A;  3N9L A;  2F6J A;  2XB1 A;  2ECW A;  3HQI A;  2LRI C;  5B78 A;  2KWJ A;  1MM2 A;  5B75 A;  2KIZ A;  2CSZ A;  4GJH A;  1D0J A;  1VFY A;  2LGV A;  2JMJ A;  4QF2 A;  3ZJB A;  1VYX A;  1LB5 A;  1FP0 A;  2EOD A;  4UP0 A;  2RSD A;  4Q6F A;  3ZPV 1;  4IC2 A;  2G6Q A;  2OXQ C;  2AN6 A;  3KQI A;  5LCW B;  4GWM A;  2KWN A;  1CZZ A;  3IVB A;  2VJF B;  5B8D A;  1WEP A;  3T6R A;  3C6W A;  4AVX A;  1F62 A;  5J3X A;  2XEU A;  2LN0 A;  4NN2 A;  3PUR A;  1WIL A;  1X4U A;  4YAD A;  3KNV A;  4B86 C;  2F6N A;  3L1X A;  4A4B A;  1VD4 A;  4A49 A;  1WFK A;  3FL2 A;  4GNG A;  3N9P A;  2YSJ A;  2LGG A;  1YY6 A;  4I7D A;  1D0A A;  2FOJ A;  2CKL B;  3QZV A;  2K1J A;  2M6M A;  4S3O B;  3EB6 A;  2QIC A;  5LKZ A;  2IDA A;  3MHS A;  1ZMS A;  2YQL A;  1T1H A;  3MQR A;  2MNZ A;  3C5K A;  3O35 A;  4XI1 A;  4M4E A;  4GWN A;  4ZQL A;  2JMI A;  1D00 A;  1CA4 A;  3HCU A;  4L7X A;  4ZUX U;  1MM3 A;  4PTB A;  1HYI A;  1K2F A;  1U6G B;  1WE9 A;  2YRE A;  1BOR A;  1D01 A;  5D1K B;  4BHW A;  4WZ3 B;  2EGP A;  4LLB A;  5AIT A;  2L43 A;  2VPE A;  3U5M A;  4R7E A;  2E6S A;  4MVT A;  2HYE D;  1F3V B;  2LXP C;  5I3L A;  3LQH A;  2KRE A;  2LDR A;  5C11 A;  3ASL A;  2ECJ A;  2LXH C;  4WA6 A;  1DVP A;  3ZYQ A;  2KYU A;  1CHC A;  2YUR A;  2YHO A;  5D1M B;  3M63 A;  4AP4 A;  2YT5 A;  4WZ2 A;  2KWK A;  1WEO A;  3ZTG A;  3DPL R;  2MIQ A;  2VJF A;  3RPG B;  2KR4 A;  3LQJ A;  2LV9 A;  2ECN A;  4GNF A;  5H1U A;  3N9O A;  2D8S A;  3L1Z B;  2MD7 B;  4R8P K;  3O70 A;  5FB1 A;  4F52 B;  4PPE A;  2MUM A;  3HU6 A;  2NAA A;  2Y1N A;  3VK6 A;  4WZ0 A;  2VJE B;  2JMD A;  4QF3 A;  5DIN A;  2GKW A;  4TKP B;  5G0F A;  2M3H A;  5G05 B;  4IC3 A;  2CKL A;  3SOX A;  1WIM A;  2CT2 A;  1XWH A;  5FB0 A;  5B77 A;  5B79 A;  1V87 A;  4AYC B;  3ZVY A;  3PHD A;  5AIU A;  3HQL A;  2EA6 A;  4YC9 A;  2MD8 C;  3N9Q A;  3LRQ A;  3I2D A;  2Y1M A;  1RF3 A;  3O36 A;  5LKT A;  2M85 A;  2KWO A;  3NG2 A;  1QSC A;  3KV6 A;  3IVQ A;  3RTR B;  4YAB A;  2QJ0 A;  4Z8M A;  2YQM A;  1YZE A;  2L5U A;  2G45 A;  5G04 B;  4BBQ A;  2YW8 A;  2H0D B;  4FJC A;  2LGK A;  2M1R A;  4YAT A;  3HCT A;  4AUQ B;  3ZNI A;  1WEQ A;  2ECT A;  2LGL A;  2VPD A;  4I7B A;  1WES A;  5TRB A;  3T7L A;  4UP5 A;  4S3O C;  4W4U A;  2F1W A;  2VPG A;  1E4U A;  1HYJ A;  3MHH A;  1JM7 B;  5FEY A;  4N4F A;  3GV4 A;  5TBN A;  4LJN A;  4FK5 A;  2YUC A;  4UI9 B;  1LB4 A;  2K4D A;  2F1X A;  4O64 A;  2FOP A;  4LK9 A;  2FSA A;  1LDJ B;  3ZPV E;  1WEW A;  2VJE A;  4YAX A;  4MSX A;  4V3K C;  1CZY A;  2K16 A;  1WEU A;  5LKX A;  2MT5 A;  1RMD A;  3IVV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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