4I7CA

Siah1 mutant bound to synthetic peptide (ace)klrpv(23p)mvrpwvr
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
192
structure length
188
Chain Sequence
ANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSICTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-based design of covalent siah inhibitors.
pubmed doi rcsb
molecule tags Ligase/ligase inhibitor
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase SIAH1
total genus 45
structure length 188
sequence length 192
chains with identical sequence C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2012-11-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 4i7cA02
3.30.40.10 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Zinc/RING finger domain, C3HC4 (zinc finger) 4i7cA01
5TDRA 1D01A 2FOPA 2K4DA 2YSJA 4I7CA 4GNEA 3N9MA 5FB1A 1BORA 2LGVA 4V3KC 3O33A 2JMJA 2KWOA 4GWMA 3IVQA 4UP0A 5LKXA 2ECTA 2QJ0A 2XEUA 3DPLR 2YU4A 2YHNA 3HQLA 2VPDA 2VNFA 2QICA 2XB1A 2M6MA 5LKZA 3LRQA 1VYXA 4LADB 2HYED 1Z6UA 3HCTA 2VPBA 3ZYQA 2FUIA 5FEYA 1VD4A 4AP4A 4AYCA 4B7YC 4UI9B 4YBMA 3U5NA 3T6RA 2KYUA 4ZUXU 4WZ3B 4MVTA 1U6GB 1HYIA 2LXPC 2LV9A 4YBSA 5H1TA 3PURA 3MQSC 5FB0A 2YURA 3LQJA 4UP5A 4O1VA 3MHSA 2Y1MA 4KG9A 3SOUA 3RPGC 4FIPA 2E6RA 4Q6FA 2UZGA 1D0JA 2MNZA 1E4UA 1X4UA 3KNVA 2KWNA 2K17A 1N87A 2RSDA 4PTBA 3V43A 4BBQA 2H0DB 3N9PA 2K1JA 2VP7A 2VPGA 1K2FA 3ZNIA 1IYMA 3O7AA 5C11A 3N9LA 2L0BA 3O37A 1WEPA 5FERA 2FUUA 5B8DA 4FK5A 2G43A 4NN2A 4K8UA 3HSVA 3C5KA 3LQHA 1F3VB 1L0AA 2PUYA 1WEEA 3VK6A 5B78A 2YQLA 5D1KB 5JG6A 1KZZA 1T1HA 3MHHA 2MD7B 2ECIA 5KH9A 2CSZA 2ECNA 2JMIA 1WE9A 1MM2A 2ZETC 3KV6A 3GL6A 3GV4A 2L5UA 2MA5A 2FOJA 4LKAA 2PNXA 2QIZA 2CR2A 5C13A 1ZMSA 3ZJBA 2CSYA 4B86C 2ECJA 4GNFA 1JM7B 2LGLA 1WEWA 3KQIA 4A0CD 2VJFB 2AN6A 2IDAA 4YC9A 3QZVA 4N4FA 1WILA 2VJFA 4WA6A 2YUCA 2L75A 4YAXA 3HTKC 2JMDA 4IC2A 4A4CA 2F1WA 4F52B 4R8PK 2EODA 2D8SA 1D00A 1WFKA 2CKLB 3EB5A 5G04B 1JOCA 4LLBA 2G45A 4PPEA 4GNGA 4AVXA 1CA4A 5B75A 2CKLA 5LKUA 2YT5A 2LGKA 4L58A 5LCWB 3ZVZB 4M4EA 2LRIC 2YHOA 1LDKC 2GKWA 4TKPB 3ZVYA 4LK9A 1ZBDB 3U5MA 4IC3A 5KH7A 3SOWA 5I3LA 3C6WA 3O35A 4CA1A 3L1ZB 1CHCA 3HQHA 5B77A 4GWNA 4YABA 2YW8A 1FP0A 2G6QA 2RI7A 5D1LB 4AUQB 2MT5A 3U5PA 1HYJA 4A49A 3T7LA 4R2YA 4I7BA 2LQ6A 3O70A 1YY6A 2H0DA 3HCUA 3L11A 5B79A 5G05B 5AIUA 4YSIA 2LGGA 2YYRA 3L1XA 2MIQA 4FO9A 2F42A 1WEVA 1Z2QA 4FJCA 1WIMA 5TABA 1WENA 1FLLA 5H9MA 4N3WA 3U5OA 1WGMA 1WEQA 3ZPV1 4ZDTA 2F1XA 2K16A 2MNYA 4S3OB 1Z60A 2NAAA 4GNDA 4JJQA 2MD8C 2CT2A 5D1MB 2KWKA 1FLKA 2Y43A 4X3GA 2JRJA 3LQIA 1QSCA 3MQRA 4YATA 4WZ2A 2BAYA 4YADA 2HDPA 2XXNA 1LB5A 4Z8MA 1LDJB 4QF3A 2M1RA 2FOOA 2C2VS 3HCSA 2LN0A 3HQMA 2MA6A 2F1YA 2KE1A 2KR4A 4A4BA 1JM7A 2EA6A 3DQVR 3PUQA 2FSAA 2YREA 1RMDA 2F1ZA 2KGIA 5TBNA 1VFYA 3IVVA 1YZEA 4QF2A 3RTRB 3N9NA 3ZTGA 3O36A 4O64A 4V3LC 2VPEA 5B76A 2VJEB 5TDWA 2LXHC 5G0FA 4L7XA 2M85A 2ECVA 2C2LA 5KH3A 2MUMA 1D0AA 2VJEA 2F6NA 4I7DA 5H1VA 4AYCB 5DKAA 1WEMA 3O34A 4ZQLA 4GJHA 3ASLA 2ECWA 1LB4A 4CCGX 2F6JA 1WESA 3M63A 1XWHA 3IHPA 3HU6A 1F62A 1G25A 3N9QA 2Y1NA 2L43A 2DX8A 3FL2A 3SOXA 1CZYA 3PHDA 5E1TA 2YQMA 1MM3A 3EB6A 5EYAF 2KGGA 5J3XA 4P5OB 2A25A 3RPGB 4MSXA 4W4UA 4LJNA 4R7EA 3NG2A 1WEOA 1DVPA 2YSMA 2KIZA 4XI1A 3I2DA 2LDRA 4YBTA 4GHUA 3KV5A 1X4IA 3HQIA 4BHWA 1RF3A 2M3HA 5LKTA 1CZZA 2ECGA 4S3OC 2E6SA 1X4JA 3M99A 1WEUA 2EGPA 4C9ZA 3M62A 2KWJA 5AITA 2KU3A 1V87A 4WZ0A 3ZPVE 1CA9A 3IVBA 2I50A 4GB0A 5DINA 2L80A 3SHBA 3N9OA 2KREA 5TRBA 2KFTA 5H1UA 2OXQC 1FBVA 1LB6A
chains in the Genus database with same CATH superfamily
5TDRA 1D01A 2FOPA 2K4DA 5K3QA 3LDYA 2EGMA 2YSJA 4I7CA 4GNEA 3N9MA 5FB1A 1BORA 2LGVA 4V3KC 3O33A 2JMJA 2KWOA 4GWMA 4O62A 3IVQA 2FFWA 3FANA 4UP0A 5LKXA 2ECTA 2QJ0A 2XEUA 3DPLR 2YU4A 2YHNA 3HQLA 2VPDA 2VNFA 2QICA 2XB1A 2M6MA 5LKZA 3LRQA 1VYXA 4LADB 2HYED 1Z6UA 4Z0RA 3HCTA 2VPBA 3ZYQA 2FUIA 5FEYA 1VD4A 4AP4A 4AYCA 4B7YC 4UI9B 2RR4A 4YBMA 3U5NA 3T6RA 2KYUA 4ZUXU 4WZ3B 4MVTA 1U6GB 1HYIA 2LXPC 2LV9A 3H7HA 4YBSA 5H1TA 3PURA 3MQSC 5FB0A 3LVQE 2YURA 3LQJA 4UP5A 4O1VA 3MHSA 5SVIA 2Y1MA 4KG9A 3SOUA 3RPGC 4FIPA 2E6RA 4Q6FA 2UZGA 1D0JA 2MNZA 1E4UA 1X4UA 3KNVA 2KWNA 2K17A 4H9DA 1N87A 2RSDA 4PTBA 3V43A 4BBQA 2H0DB 3N9PA 2K1JA 2XOYA 2VP7A 2VPGA 1K2FA 3ZNIA 1IYMA 3O7AA 5C11A 3N9LA 4F1PA 2L0BA 3O37A 1WEPA 3FAOA 5FERA 2FUUA 3E2DA 5B8DA 4FK5A 2G43A 4K8UA 4NN2A 3HSVA 3C5KA 3LQHA 1F3VB 1L0AA 2PUYA 1WEEA 3VK6A 5B78A 2YQLA 5D1KB 5JG6A 1KZZA 1T1HA 2JM3A 3MHHA 2MD7B 2ECIA 5KH9A 2CSZA 2ECNA 2JMIA 1WE9A 1MM2A 2ZETC 3KV6A 3GL6A 3GV4A 3DDTA 2L5UA 2MA5A 2FOJA 4LKAA 2PNXA 2M13A 2KKXA 2QIZA 2CR2A 5C13A 1ZMSA 3ZJBA 2CSYA 4B86C 2ECJA 2DJAA 4GNFA 1MBMA 1JM7B 2LGLA 1WEWA 3KQIA 4A0CD 2VJFB 2AN6A 2IDAA 4YC9A 3QZVA 2MKEA 4N4FA 1WILA 2VJFA 4WA6A 2YUCA 2LAUA 2L75A 4YAXA 3JUEA 2XOZA 3HTKC 2JMDA 4IC2A 4A4CA 2F1WA 4F52B 4R8PK 2EODA 2D8SA 1D00A 1WFKA 2CKLB 3EB5A 5G04B 1JOCA 4LLBA 2G45A 4PPEA 4GNGA 4AVXA 1CA4A 5B75A 2CKLA 4Z0OA 5LKUA 2YT5A 2LGKA 4L58A 5LCWB 3ZVZB 4M4EA 2LRIC 2YHOA 1LDKC 2GKWA 4TKPB 3ZVYA 4LK9A 1ZBDB 3U5MA 4IC3A 5KH7A 3SOWA 5I3LA 2IQJA 3C6WA 3O35A 4CA1A 3L1ZB 3SUBA 1CHCA 3HQHA 5B77A 4GWNA 4YABA 2YW8A 1FP0A 2G6QA 2RI7A 5D1LB 4AUQB 2CRWA 2MT5A 4QQ4A 3U5PA 1HYJA 4A49A 3T7LA 4R2YA 5SVYA 2JUNA 4I7BA 2LQ6A 3O70A 2FD4A 1YY6A 2H0DA 3HCUA 3L11A 5B79A 5G05B 5AIUA 4YSIA 2LGGA 2YYRA 3L1XA 2P57A 2MIQA 4FO9A 2F42A 1WEVA 1Z2QA 2CRRA 4FJCA 1WIMA 5TABA 1WENA 1FLLA 5H9MA 4N3WA 3U5OA 1WGMA 3LJUX 2E61A 1WEQA 3ZPV1 4ZDTA 2F1XA 2K16A 2MNYA 4S3OB 1Z60A 2NAAA 4GNDA 4JJQA 2MD8C 2CT2A 4OGCA 3MDBC 5D1MB 2KWKA 3M7KA 1FLKA 2Y43A 4X3GA 2JRJA 3DWDA 3LQIA 1QSCA 3MQRA 4YATA 4WZ2A 2BAYA 4YADA 2HDPA 2XXNA 2CONA 1LB5A 4Z8MA 1LDJB 2XOCA 2M1RA 2FOOA 4QF3A 2C2VS 3HCSA 2LN0A 3HQMA 2MA6A 2F1YA 2KE1A 2KR4A 4A4BA 1JM7A 2EA6A 3LVRE 3DQVR 3PUQA 2FSAA 2YREA 1RMDA 2F1ZA 2KGIA 5TBNA 2D8UA 1VFYA 3IVVA 1YZEA 4QF2A 3RTRB 3N9NA 2OWAA 3ZTGA 3O36A 4O64A 4V3LC 2VPEA 5B76A 2VJEB 5TDWA 3O47A 2EXUA 2LXHC 5G0FA 4L7XA 2M85A 2ECVA 2C2LA 5KH3A 2MUMA 1D0AA 2VJEA 2F6NA 2B0OE 4I7DA 5H1VA 4AYCB 5DKAA 1WEMA 3T9KA 3O34A 4ZQLA 4GJHA 3ASLA 2L7PA 2ECWA 1LB4A 4CCGX 2F6JA 1WESA 3FM8C 2DSMA 3M63A 1XWHA 3IHPA 3HU6A 2XP0A 1F62A 1G25A 3N9QA 2Y1NA 5SVIB 2L43A 2DX8A 3FL2A 3SOXA 1CZYA 3PHDA 5E1TA 2YQMA 1MM3A 3EB6A 5EYAF 2KGGA 4OGEA 5J3XA 4P5OB 2A25A 3RPGB 4MSXA 4W4UA 4LJNA 4R7EA 3PLWA 2CSVA 3NG2A 1WEOA 1DVPA 2YSMA 2YVRA 2KIZA 4XI1A 3I2DA 2LDRA 5SVXA 4YBTA 4GHUA 3KV5A 3KDEC 1X4IA 3HQIA 4BHWA 1RF3A 2M3HA 5LKTA 1CZZA 2ECGA 4S3OC 2E6SA 1X4JA 3M99A 1WEUA 2EGPA 4C9ZA 3M62A 2KWJA 3Q1DA 5AITA 2KU3A 1V87A 4WZ0A 3ZPVE 1CA9A 3IVBA 2I50A 4GB0A 5DINA 2L80A 1DCQA 3SHBA 3N9OA 2KREA 5TRBA 3FJUB 3FEHA 2KFTA 5H1UA 2OXQC 1FBVA 1LB6A 2KKYA
chains in the Genus database with same CATH topology
5TDRA 1D01A 2FOPA 2K4DA 2YSJA 4I7CA 4GNEA 3N9MA 5FB1A 1BORA 2LGVA 4V3KC 3O33A 2JMJA 2KWOA 4GWMA 3IVQA 4UP0A 5LKXA 2ECTA 2QJ0A 2XEUA 3DPLR 2YU4A 2YHNA 3HQLA 2VPDA 2VNFA 2QICA 2XB1A 2M6MA 5LKZA 3LRQA 1VYXA 4LADB 2HYED 1Z6UA 3HCTA 2VPBA 3ZYQA 2FUIA 5FEYA 1VD4A 4AP4A 4AYCA 4B7YC 4UI9B 4YBMA 3U5NA 3T6RA 2KYUA 4ZUXU 4WZ3B 4MVTA 1U6GB 1HYIA 2LXPC 2LV9A 4YBSA 5H1TA 3PURA 3MQSC 5FB0A 2YURA 3LQJA 4UP5A 4O1VA 3MHSA 2Y1MA 4KG9A 3SOUA 3RPGC 4FIPA 2E6RA 4Q6FA 2UZGA 1D0JA 2MNZA 1E4UA 1X4UA 3KNVA 2KWNA 2K17A 1N87A 2RSDA 4PTBA 3V43A 4BBQA 2H0DB 3N9PA 2K1JA 2VP7A 2VPGA 1K2FA 3ZNIA 1IYMA 3O7AA 5C11A 3N9LA 2L0BA 3O37A 1WEPA 5FERA 2FUUA 5B8DA 4FK5A 2G43A 4NN2A 4K8UA 3HSVA 3C5KA 3LQHA 1F3VB 1L0AA 2PUYA 1WEEA 3VK6A 5B78A 2YQLA 5D1KB 5JG6A 1KZZA 1T1HA 3MHHA 2MD7B 2ECIA 5KH9A 2CSZA 2ECNA 2JMIA 1WE9A 1MM2A 2ZETC 3KV6A 3GL6A 3GV4A 2L5UA 2MA5A 2FOJA 4LKAA 2PNXA 2QIZA 2CR2A 5C13A 1ZMSA 3ZJBA 2CSYA 4B86C 2ECJA 4GNFA 1JM7B 2LGLA 1WEWA 3KQIA 4A0CD 2VJFB 2AN6A 2IDAA 4YC9A 3QZVA 4N4FA 1WILA 2VJFA 4WA6A 2YUCA 2L75A 4YAXA 3HTKC 2JMDA 4IC2A 4A4CA 2F1WA 4F52B 4R8PK 2EODA 2D8SA 1D00A 1WFKA 2CKLB 3EB5A 5G04B 1JOCA 4LLBA 2G45A 4PPEA 4GNGA 4AVXA 1CA4A 5B75A 2CKLA 5LKUA 2YT5A 2LGKA 4L58A 5LCWB 3ZVZB 4M4EA 2LRIC 2YHOA 1LDKC 2GKWA 4TKPB 3ZVYA 4LK9A 1ZBDB 3U5MA 4IC3A 5KH7A 3SOWA 5I3LA 3C6WA 3O35A 4CA1A 3L1ZB 1CHCA 3HQHA 5B77A 4GWNA 4YABA 2YW8A 1FP0A 2G6QA 2RI7A 5D1LB 4AUQB 2MT5A 3U5PA 1HYJA 4A49A 3T7LA 4R2YA 4I7BA 2LQ6A 3O70A 1YY6A 2H0DA 3HCUA 3L11A 5B79A 5G05B 5AIUA 4YSIA 2LGGA 2YYRA 3L1XA 2MIQA 4FO9A 2F42A 1WEVA 1Z2QA 4FJCA 1WIMA 5TABA 1WENA 1FLLA 5H9MA 4N3WA 3U5OA 1WGMA 1WEQA 3ZPV1 4ZDTA 2F1XA 2K16A 2MNYA 4S3OB 1Z60A 2NAAA 4GNDA 4JJQA 2MD8C 2CT2A 5D1MB 2KWKA 1FLKA 2Y43A 4X3GA 2JRJA 3LQIA 1QSCA 3MQRA 4YATA 4WZ2A 2BAYA 4YADA 2HDPA 2XXNA 1LB5A 4Z8MA 1LDJB 4QF3A 2M1RA 2FOOA 2C2VS 3HCSA 2LN0A 3HQMA 2MA6A 2F1YA 2KE1A 2KR4A 4A4BA 1JM7A 2EA6A 3DQVR 3PUQA 2FSAA 2YREA 1RMDA 2F1ZA 2KGIA 5TBNA 1VFYA 3IVVA 1YZEA 4QF2A 3RTRB 3N9NA 3ZTGA 3O36A 4O64A 4V3LC 2VPEA 5B76A 2VJEB 5TDWA 2LXHC 5G0FA 4L7XA 2M85A 2ECVA 2C2LA 5KH3A 2MUMA 1D0AA 2VJEA 2F6NA 4I7DA 5H1VA 4AYCB 5DKAA 1WEMA 3O34A 4ZQLA 4GJHA 3ASLA 2ECWA 1LB4A 4CCGX 2F6JA 1WESA 3M63A 1XWHA 3IHPA 3HU6A 1F62A 1G25A 3N9QA 2Y1NA 2L43A 2DX8A 3FL2A 3SOXA 1CZYA 3PHDA 5E1TA 2YQMA 1MM3A 3EB6A 5EYAF 2KGGA 5J3XA 4P5OB 2A25A 3RPGB 4MSXA 4W4UA 4LJNA 4R7EA 3NG2A 1WEOA 1DVPA 2YSMA 2KIZA 4XI1A 3I2DA 2LDRA 4YBTA 4GHUA 3KV5A 1X4IA 3HQIA 4BHWA 1RF3A 2M3HA 5LKTA 1CZZA 2ECGA 4S3OC 2E6SA 1X4JA 3M99A 1WEUA 2EGPA 4C9ZA 3M62A 2KWJA 5AITA 2KU3A 1V87A 4WZ0A 3ZPVE 1CA9A 3IVBA 2I50A 4GB0A 5DINA 2L80A 3SHBA 3N9OA 2KREA 5TRBA 2KFTA 5H1UA 2OXQC 1FBVA 1LB6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5TDR A;  1D01 A;  2FOP A;  2K4D A;  2YSJ A;  4I7C A;  4GNE A;  3N9M A;  5FB1 A;  1BOR A;  2LGV A;  4V3K C;  3O33 A;  2JMJ A;  2KWO A;  4GWM A;  3IVQ A;  4UP0 A;  5LKX A;  2ECT A;  2QJ0 A;  2XEU A;  3DPL R;  2YU4 A;  2YHN A;  3HQL A;  2VPD A;  2VNF A;  2QIC A;  2XB1 A;  2M6M A;  5LKZ A;  3LRQ A;  1VYX A;  4LAD B;  2HYE D;  1Z6U A;  3HCT A;  2VPB A;  3ZYQ A;  2FUI A;  5FEY A;  1VD4 A;  4AP4 A;  4AYC A;  4B7Y C;  4UI9 B;  4YBM A;  3U5N A;  3T6R A;  2KYU A;  4ZUX U;  4WZ3 B;  4MVT A;  1U6G B;  1HYI A;  2LXP C;  2LV9 A;  4YBS A;  5H1T A;  3PUR A;  3MQS C;  5FB0 A;  2YUR A;  3LQJ A;  4UP5 A;  4O1V A;  3MHS A;  2Y1M A;  4KG9 A;  3SOU A;  3RPG C;  4FIP A;  2E6R A;  4Q6F A;  2UZG A;  1D0J A;  2MNZ A;  1E4U A;  1X4U A;  3KNV A;  2KWN A;  2K17 A;  1N87 A;  2RSD A;  4PTB A;  3V43 A;  4BBQ A;  2H0D B;  3N9P A;  2K1J A;  2VP7 A;  2VPG A;  1K2F A;  3ZNI A;  1IYM A;  3O7A A;  5C11 A;  3N9L A;  2L0B A;  3O37 A;  1WEP A;  5FER A;  2FUU A;  5B8D A;  4FK5 A;  2G43 A;  4NN2 A;  4K8U A;  3HSV A;  3C5K A;  3LQH A;  1F3V B;  1L0A A;  2PUY A;  1WEE A;  3VK6 A;  5B78 A;  2YQL A;  5D1K B;  5JG6 A;  1KZZ A;  1T1H A;  3MHH A;  2MD7 B;  2ECI A;  5KH9 A;  2CSZ A;  2ECN A;  2JMI A;  1WE9 A;  1MM2 A;  2ZET C;  3KV6 A;  3GL6 A;  3GV4 A;  2L5U A;  2MA5 A;  2FOJ A;  4LKA A;  2PNX A;  2QIZ A;  2CR2 A;  5C13 A;  1ZMS A;  3ZJB A;  2CSY A;  4B86 C;  2ECJ A;  4GNF A;  1JM7 B;  2LGL A;  1WEW A;  3KQI A;  4A0C D;  2VJF B;  2AN6 A;  2IDA A;  4YC9 A;  3QZV A;  4N4F A;  1WIL A;  2VJF A;  4WA6 A;  2YUC A;  2L75 A;  4YAX A;  3HTK C;  2JMD A;  4IC2 A;  4A4C A;  2F1W A;  4F52 B;  4R8P K;  2EOD A;  2D8S A;  1D00 A;  1WFK A;  2CKL B;  3EB5 A;  5G04 B;  1JOC A;  4LLB A;  2G45 A;  4PPE A;  4GNG A;  4AVX A;  1CA4 A;  5B75 A;  2CKL A;  5LKU A;  2YT5 A;  2LGK A;  4L58 A;  5LCW B;  3ZVZ B;  4M4E A;  2LRI C;  2YHO A;  1LDK C;  2GKW A;  4TKP B;  3ZVY A;  4LK9 A;  1ZBD B;  3U5M A;  4IC3 A;  5KH7 A;  3SOW A;  5I3L A;  3C6W A;  3O35 A;  4CA1 A;  3L1Z B;  1CHC A;  3HQH A;  5B77 A;  4GWN A;  4YAB A;  2YW8 A;  1FP0 A;  2G6Q A;  2RI7 A;  5D1L B;  4AUQ B;  2MT5 A;  3U5P A;  1HYJ A;  4A49 A;  3T7L A;  4R2Y A;  4I7B A;  2LQ6 A;  3O70 A;  1YY6 A;  2H0D A;  3HCU A;  3L11 A;  5B79 A;  5G05 B;  5AIU A;  4YSI A;  2LGG A;  2YYR A;  3L1X A;  2MIQ A;  4FO9 A;  2F42 A;  1WEV A;  1Z2Q A;  4FJC A;  1WIM A;  5TAB A;  1WEN A;  1FLL A;  5H9M A;  4N3W A;  3U5O A;  1WGM A;  1WEQ A;  3ZPV 1;  4ZDT A;  2F1X A;  2K16 A;  2MNY A;  4S3O B;  1Z60 A;  2NAA A;  4GND A;  4JJQ A;  2MD8 C;  2CT2 A;  5D1M B;  2KWK A;  1FLK A;  2Y43 A;  4X3G A;  2JRJ A;  3LQI A;  1QSC A;  3MQR A;  4YAT A;  4WZ2 A;  2BAY A;  4YAD A;  2HDP A;  2XXN A;  1LB5 A;  4Z8M A;  1LDJ B;  4QF3 A;  2M1R A;  2FOO A;  2C2V S;  3HCS A;  2LN0 A;  3HQM A;  2MA6 A;  2F1Y A;  2KE1 A;  2KR4 A;  4A4B A;  1JM7 A;  2EA6 A;  3DQV R;  3PUQ A;  2FSA A;  2YRE A;  1RMD A;  2F1Z A;  2KGI A;  5TBN A;  1VFY A;  3IVV A;  1YZE A;  4QF2 A;  3RTR B;  3N9N A;  3ZTG A;  3O36 A;  4O64 A;  4V3L C;  2VPE A;  5B76 A;  2VJE B;  5TDW A;  2LXH C;  5G0F A;  4L7X A;  2M85 A;  2ECV A;  2C2L A;  5KH3 A;  2MUM A;  1D0A A;  2VJE A;  2F6N A;  4I7D A;  5H1V A;  4AYC B;  5DKA A;  1WEM A;  3O34 A;  4ZQL A;  4GJH A;  3ASL A;  2ECW A;  1LB4 A;  4CCG X;  2F6J A;  1WES A;  3M63 A;  1XWH A;  3IHP A;  3HU6 A;  1F62 A;  1G25 A;  3N9Q A;  2Y1N A;  2L43 A;  2DX8 A;  3FL2 A;  3SOX A;  1CZY A;  3PHD A;  5E1T A;  2YQM A;  1MM3 A;  3EB6 A;  5EYA F;  2KGG A;  5J3X A;  4P5O B;  2A25 A;  3RPG B;  4MSX A;  4W4U A;  4LJN A;  4R7E A;  3NG2 A;  1WEO A;  1DVP A;  2YSM A;  2KIZ A;  4XI1 A;  3I2D A;  2LDR A;  4YBT A;  4GHU A;  3KV5 A;  1X4I A;  3HQI A;  4BHW A;  1RF3 A;  2M3H A;  5LKT A;  1CZZ A;  2ECG A;  4S3O C;  2E6S A;  1X4J A;  3M99 A;  1WEU A;  2EGP A;  4C9Z A;  3M62 A;  2KWJ A;  5AIT A;  2KU3 A;  1V87 A;  4WZ0 A;  3ZPV E;  1CA9 A;  3IVB A;  2I50 A;  4GB0 A;  5DIN A;  2L80 A;  3SHB A;  3N9O A;  2KRE A;  5TRB A;  2KFT A;  5H1U A;  2OXQ C;  1FBV A;  1LB6 A; 
#chains in the Genus database with same CATH topology
 5TDR A;  1D01 A;  2FOP A;  2K4D A;  5K3Q A;  3LDY A;  2EGM A;  2YSJ A;  4I7C A;  4GNE A;  3N9M A;  5FB1 A;  1BOR A;  2LGV A;  4V3K C;  3O33 A;  2JMJ A;  2KWO A;  4GWM A;  4O62 A;  3IVQ A;  2FFW A;  3FAN A;  4UP0 A;  5LKX A;  2ECT A;  2QJ0 A;  2XEU A;  3DPL R;  2YU4 A;  2YHN A;  3HQL A;  2VPD A;  2VNF A;  2QIC A;  2XB1 A;  2M6M A;  5LKZ A;  3LRQ A;  1VYX A;  4LAD B;  2HYE D;  1Z6U A;  4Z0R A;  3HCT A;  2VPB A;  3ZYQ A;  2FUI A;  5FEY A;  1VD4 A;  4AP4 A;  4AYC A;  4B7Y C;  4UI9 B;  2RR4 A;  4YBM A;  3U5N A;  3T6R A;  2KYU A;  4ZUX U;  4WZ3 B;  4MVT A;  1U6G B;  1HYI A;  2LXP C;  2LV9 A;  3H7H A;  4YBS A;  5H1T A;  3PUR A;  3MQS C;  5FB0 A;  3LVQ E;  2YUR A;  3LQJ A;  4UP5 A;  4O1V A;  3MHS A;  5SVI A;  2Y1M A;  4KG9 A;  3SOU A;  3RPG C;  4FIP A;  2E6R A;  4Q6F A;  2UZG A;  1D0J A;  2MNZ A;  1E4U A;  1X4U A;  3KNV A;  2KWN A;  2K17 A;  4H9D A;  1N87 A;  2RSD A;  4PTB A;  3V43 A;  4BBQ A;  2H0D B;  3N9P A;  2K1J A;  2XOY A;  2VP7 A;  2VPG A;  1K2F A;  3ZNI A;  1IYM A;  3O7A A;  5C11 A;  3N9L A;  4F1P A;  2L0B A;  3O37 A;  1WEP A;  3FAO A;  5FER A;  2FUU A;  3E2D A;  5B8D A;  4FK5 A;  2G43 A;  4K8U A;  4NN2 A;  3HSV A;  3C5K A;  3LQH A;  1F3V B;  1L0A A;  2PUY A;  1WEE A;  3VK6 A;  5B78 A;  2YQL A;  5D1K B;  5JG6 A;  1KZZ A;  1T1H A;  2JM3 A;  3MHH A;  2MD7 B;  2ECI A;  5KH9 A;  2CSZ A;  2ECN A;  2JMI A;  1WE9 A;  1MM2 A;  2ZET C;  3KV6 A;  3GL6 A;  3GV4 A;  3DDT A;  2L5U A;  2MA5 A;  2FOJ A;  4LKA A;  2PNX A;  2M13 A;  2KKX A;  2QIZ A;  2CR2 A;  5C13 A;  1ZMS A;  3ZJB A;  2CSY A;  4B86 C;  2ECJ A;  2DJA A;  4GNF A;  1MBM A;  1JM7 B;  2LGL A;  1WEW A;  3KQI A;  4A0C D;  2VJF B;  2AN6 A;  2IDA A;  4YC9 A;  3QZV A;  2MKE A;  4N4F A;  1WIL A;  2VJF A;  4WA6 A;  2YUC A;  2LAU A;  2L75 A;  4YAX A;  3JUE A;  2XOZ A;  3HTK C;  2JMD A;  4IC2 A;  4A4C A;  2F1W A;  4F52 B;  4R8P K;  2EOD A;  2D8S A;  1D00 A;  1WFK A;  2CKL B;  3EB5 A;  5G04 B;  1JOC A;  4LLB A;  2G45 A;  4PPE A;  4GNG A;  4AVX A;  1CA4 A;  5B75 A;  2CKL A;  4Z0O A;  5LKU A;  2YT5 A;  2LGK A;  4L58 A;  5LCW B;  3ZVZ B;  4M4E A;  2LRI C;  2YHO A;  1LDK C;  2GKW A;  4TKP B;  3ZVY A;  4LK9 A;  1ZBD B;  3U5M A;  4IC3 A;  5KH7 A;  3SOW A;  5I3L A;  2IQJ A;  3C6W A;  3O35 A;  4CA1 A;  3L1Z B;  3SUB A;  1CHC A;  3HQH A;  5B77 A;  4GWN A;  4YAB A;  2YW8 A;  1FP0 A;  2G6Q A;  2RI7 A;  5D1L B;  4AUQ B;  2CRW A;  2MT5 A;  4QQ4 A;  3U5P A;  1HYJ A;  4A49 A;  3T7L A;  4R2Y A;  5SVY A;  2JUN A;  4I7B A;  2LQ6 A;  3O70 A;  2FD4 A;  1YY6 A;  2H0D A;  3HCU A;  3L11 A;  5B79 A;  5G05 B;  5AIU A;  4YSI A;  2LGG A;  2YYR A;  3L1X A;  2P57 A;  2MIQ A;  4FO9 A;  2F42 A;  1WEV A;  1Z2Q A;  2CRR A;  4FJC A;  1WIM A;  5TAB A;  1WEN A;  1FLL A;  5H9M A;  4N3W A;  3U5O A;  1WGM A;  3LJU X;  2E61 A;  1WEQ A;  3ZPV 1;  4ZDT A;  2F1X A;  2K16 A;  2MNY A;  4S3O B;  1Z60 A;  2NAA A;  4GND A;  4JJQ A;  2MD8 C;  2CT2 A;  4OGC A;  3MDB C;  5D1M B;  2KWK A;  3M7K A;  1FLK A;  2Y43 A;  4X3G A;  2JRJ A;  3DWD A;  3LQI A;  1QSC A;  3MQR A;  4YAT A;  4WZ2 A;  2BAY A;  4YAD A;  2HDP A;  2XXN A;  2CON A;  1LB5 A;  4Z8M A;  1LDJ B;  2XOC A;  2M1R A;  2FOO A;  4QF3 A;  2C2V S;  3HCS A;  2LN0 A;  3HQM A;  2MA6 A;  2F1Y A;  2KE1 A;  2KR4 A;  4A4B A;  1JM7 A;  2EA6 A;  3LVR E;  3DQV R;  3PUQ A;  2FSA A;  2YRE A;  1RMD A;  2F1Z A;  2KGI A;  5TBN A;  2D8U A;  1VFY A;  3IVV A;  1YZE A;  4QF2 A;  3RTR B;  3N9N A;  2OWA A;  3ZTG A;  3O36 A;  4O64 A;  4V3L C;  2VPE A;  5B76 A;  2VJE B;  5TDW A;  3O47 A;  2EXU A;  2LXH C;  5G0F A;  4L7X A;  2M85 A;  2ECV A;  2C2L A;  5KH3 A;  2MUM A;  1D0A A;  2VJE A;  2F6N A;  2B0O E;  4I7D A;  5H1V A;  4AYC B;  5DKA A;  1WEM A;  3T9K A;  3O34 A;  4ZQL A;  4GJH A;  3ASL A;  2L7P A;  2ECW A;  1LB4 A;  4CCG X;  2F6J A;  1WES A;  3FM8 C;  2DSM A;  3M63 A;  1XWH A;  3IHP A;  3HU6 A;  2XP0 A;  1F62 A;  1G25 A;  3N9Q A;  2Y1N A;  5SVI B;  2L43 A;  2DX8 A;  3FL2 A;  3SOX A;  1CZY A;  3PHD A;  5E1T A;  2YQM A;  1MM3 A;  3EB6 A;  5EYA F;  2KGG A;  4OGE A;  5J3X A;  4P5O B;  2A25 A;  3RPG B;  4MSX A;  4W4U A;  4LJN A;  4R7E A;  3PLW A;  2CSV A;  3NG2 A;  1WEO A;  1DVP A;  2YSM A;  2YVR A;  2KIZ A;  4XI1 A;  3I2D A;  2LDR A;  5SVX A;  4YBT A;  4GHU A;  3KV5 A;  3KDE C;  1X4I A;  3HQI A;  4BHW A;  1RF3 A;  2M3H A;  5LKT A;  1CZZ A;  2ECG A;  4S3O C;  2E6S A;  1X4J A;  3M99 A;  1WEU A;  2EGP A;  4C9Z A;  3M62 A;  2KWJ A;  3Q1D A;  5AIT A;  2KU3 A;  1V87 A;  4WZ0 A;  3ZPV E;  1CA9 A;  3IVB A;  2I50 A;  4GB0 A;  5DIN A;  2L80 A;  1DCQ A;  3SHB A;  3N9O A;  2KRE A;  5TRB A;  3FJU B;  3FEH A;  2KFT A;  5H1U A;  2OXQ C;  1FBV A;  1LB6 A;  2KKY A; 
#chains in the Genus database with same CATH homology
 5TDR A;  1D01 A;  2FOP A;  2K4D A;  2YSJ A;  4I7C A;  4GNE A;  3N9M A;  5FB1 A;  1BOR A;  2LGV A;  4V3K C;  3O33 A;  2JMJ A;  2KWO A;  4GWM A;  3IVQ A;  4UP0 A;  5LKX A;  2ECT A;  2QJ0 A;  2XEU A;  3DPL R;  2YU4 A;  2YHN A;  3HQL A;  2VPD A;  2VNF A;  2QIC A;  2XB1 A;  2M6M A;  5LKZ A;  3LRQ A;  1VYX A;  4LAD B;  2HYE D;  1Z6U A;  3HCT A;  2VPB A;  3ZYQ A;  2FUI A;  5FEY A;  1VD4 A;  4AP4 A;  4AYC A;  4B7Y C;  4UI9 B;  4YBM A;  3U5N A;  3T6R A;  2KYU A;  4ZUX U;  4WZ3 B;  4MVT A;  1U6G B;  1HYI A;  2LXP C;  2LV9 A;  4YBS A;  5H1T A;  3PUR A;  3MQS C;  5FB0 A;  2YUR A;  3LQJ A;  4UP5 A;  4O1V A;  3MHS A;  2Y1M A;  4KG9 A;  3SOU A;  3RPG C;  4FIP A;  2E6R A;  4Q6F A;  2UZG A;  1D0J A;  2MNZ A;  1E4U A;  1X4U A;  3KNV A;  2KWN A;  2K17 A;  1N87 A;  2RSD A;  4PTB A;  3V43 A;  4BBQ A;  2H0D B;  3N9P A;  2K1J A;  2VP7 A;  2VPG A;  1K2F A;  3ZNI A;  1IYM A;  3O7A A;  5C11 A;  3N9L A;  2L0B A;  3O37 A;  1WEP A;  5FER A;  2FUU A;  5B8D A;  4FK5 A;  2G43 A;  4NN2 A;  4K8U A;  3HSV A;  3C5K A;  3LQH A;  1F3V B;  1L0A A;  2PUY A;  1WEE A;  3VK6 A;  5B78 A;  2YQL A;  5D1K B;  5JG6 A;  1KZZ A;  1T1H A;  3MHH A;  2MD7 B;  2ECI A;  5KH9 A;  2CSZ A;  2ECN A;  2JMI A;  1WE9 A;  1MM2 A;  2ZET C;  3KV6 A;  3GL6 A;  3GV4 A;  2L5U A;  2MA5 A;  2FOJ A;  4LKA A;  2PNX A;  2QIZ A;  2CR2 A;  5C13 A;  1ZMS A;  3ZJB A;  2CSY A;  4B86 C;  2ECJ A;  4GNF A;  1JM7 B;  2LGL A;  1WEW A;  3KQI A;  4A0C D;  2VJF B;  2AN6 A;  2IDA A;  4YC9 A;  3QZV A;  4N4F A;  1WIL A;  2VJF A;  4WA6 A;  2YUC A;  2L75 A;  4YAX A;  3HTK C;  2JMD A;  4IC2 A;  4A4C A;  2F1W A;  4F52 B;  4R8P K;  2EOD A;  2D8S A;  1D00 A;  1WFK A;  2CKL B;  3EB5 A;  5G04 B;  1JOC A;  4LLB A;  2G45 A;  4PPE A;  4GNG A;  4AVX A;  1CA4 A;  5B75 A;  2CKL A;  5LKU A;  2YT5 A;  2LGK A;  4L58 A;  5LCW B;  3ZVZ B;  4M4E A;  2LRI C;  2YHO A;  1LDK C;  2GKW A;  4TKP B;  3ZVY A;  4LK9 A;  1ZBD B;  3U5M A;  4IC3 A;  5KH7 A;  3SOW A;  5I3L A;  3C6W A;  3O35 A;  4CA1 A;  3L1Z B;  1CHC A;  3HQH A;  5B77 A;  4GWN A;  4YAB A;  2YW8 A;  1FP0 A;  2G6Q A;  2RI7 A;  5D1L B;  4AUQ B;  2MT5 A;  3U5P A;  1HYJ A;  4A49 A;  3T7L A;  4R2Y A;  4I7B A;  2LQ6 A;  3O70 A;  1YY6 A;  2H0D A;  3HCU A;  3L11 A;  5B79 A;  5G05 B;  5AIU A;  4YSI A;  2LGG A;  2YYR A;  3L1X A;  2MIQ A;  4FO9 A;  2F42 A;  1WEV A;  1Z2Q A;  4FJC A;  1WIM A;  5TAB A;  1WEN A;  1FLL A;  5H9M A;  4N3W A;  3U5O A;  1WGM A;  1WEQ A;  3ZPV 1;  4ZDT A;  2F1X A;  2K16 A;  2MNY A;  4S3O B;  1Z60 A;  2NAA A;  4GND A;  4JJQ A;  2MD8 C;  2CT2 A;  5D1M B;  2KWK A;  1FLK A;  2Y43 A;  4X3G A;  2JRJ A;  3LQI A;  1QSC A;  3MQR A;  4YAT A;  4WZ2 A;  2BAY A;  4YAD A;  2HDP A;  2XXN A;  1LB5 A;  4Z8M A;  1LDJ B;  4QF3 A;  2M1R A;  2FOO A;  2C2V S;  3HCS A;  2LN0 A;  3HQM A;  2MA6 A;  2F1Y A;  2KE1 A;  2KR4 A;  4A4B A;  1JM7 A;  2EA6 A;  3DQV R;  3PUQ A;  2FSA A;  2YRE A;  1RMD A;  2F1Z A;  2KGI A;  5TBN A;  1VFY A;  3IVV A;  1YZE A;  4QF2 A;  3RTR B;  3N9N A;  3ZTG A;  3O36 A;  4O64 A;  4V3L C;  2VPE A;  5B76 A;  2VJE B;  5TDW A;  2LXH C;  5G0F A;  4L7X A;  2M85 A;  2ECV A;  2C2L A;  5KH3 A;  2MUM A;  1D0A A;  2VJE A;  2F6N A;  4I7D A;  5H1V A;  4AYC B;  5DKA A;  1WEM A;  3O34 A;  4ZQL A;  4GJH A;  3ASL A;  2ECW A;  1LB4 A;  4CCG X;  2F6J A;  1WES A;  3M63 A;  1XWH A;  3IHP A;  3HU6 A;  1F62 A;  1G25 A;  3N9Q A;  2Y1N A;  2L43 A;  2DX8 A;  3FL2 A;  3SOX A;  1CZY A;  3PHD A;  5E1T A;  2YQM A;  1MM3 A;  3EB6 A;  5EYA F;  2KGG A;  5J3X A;  4P5O B;  2A25 A;  3RPG B;  4MSX A;  4W4U A;  4LJN A;  4R7E A;  3NG2 A;  1WEO A;  1DVP A;  2YSM A;  2KIZ A;  4XI1 A;  3I2D A;  2LDR A;  4YBT A;  4GHU A;  3KV5 A;  1X4I A;  3HQI A;  4BHW A;  1RF3 A;  2M3H A;  5LKT A;  1CZZ A;  2ECG A;  4S3O C;  2E6S A;  1X4J A;  3M99 A;  1WEU A;  2EGP A;  4C9Z A;  3M62 A;  2KWJ A;  5AIT A;  2KU3 A;  1V87 A;  4WZ0 A;  3ZPV E;  1CA9 A;  3IVB A;  2I50 A;  4GB0 A;  5DIN A;  2L80 A;  3SHB A;  3N9O A;  2KRE A;  5TRB A;  2KFT A;  5H1U A;  2OXQ C;  1FBV A;  1LB6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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