5D3YA

Crystal structure of the p-rex1 ph domain with inositol-(1,3,4,5)-tetrakisphosphate bound
Total Genus 40
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
151
structure length
136
Chain Sequence
ALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKSRVSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
pubmed doi rcsb
molecule tags Lipid binding protein
source organism Homo sapiens
molecule keywords Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac excha
total genus 40
structure length 136
sequence length 151
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-08-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 5d3yA00
2YT0A 2RGNB 2VKIA 4A6FA 2VSZA 2D10A 1OY2A 1X86A 3PEGA 5D3WA 2MKRA 2EJ8A 2DKQA 4D0NB 1XR0B 1TJ6A 1WI1A 3NSUA 1Q67A 3KSYA 4Y94A 2G35A 2LOXA 5JP4A 1UPRA 3PZDA 2RSGA 4C0AA 4HAYB 1MAIA 1K5DB 3P6AA 3QBVB 2E2XA 2CRFA 3CXBB 2EMSA 2Z0QA 4NSWA 2Y7BA 3ML4A 4EMOA 4DXAB 2DLWA 1M7EA 4IOYX 5JLJB 3F5RA 2J0KA 1U2BA 2GS0A 1WJ1A 2GCLA 2P0FA 4A6KA 2QKMA 4K17A 3KRXA 4CHMA 5L81A 4F7GA 3A8QA 4EJNA 2DTCA 5C16A 4NY0A 2ZPYA 4HAZB 4GXBA 4TYZA 4HDQA 2XQNM 2YVCA 3BINA 1LB1A 1GG3A 2CAYA 4DBBA 1XKEA 2OQBA 2K00A 2QKLA 2W2XC 1PFJA 2M14A 3HK0A 5C5BB 2LULA 3KY9A 4HAWB 4WJ7A 4H8SA 2L2IA 5C6RA 2P0DA 4HB4B 1Z87A 2UVMA 2N0YA 3FM8C 5KCVA 2RLOA 4F7HA 1WGQA 1WVHA 4L6EA 2NZ8B 1AWEA 4MK0A 1U29A 3WA0A 3HQCA 1X05A 5C5BA 2DYQA 3ULCA 1J19A 5EFXA 1QC6A 1FHXA 2ELAA 3PSCA 1B55A 1XCGA 3ZVRA 1MK9B 4P7IA 1OQNA 3OANA 2GCJA 2Y8GA 4CYEA 4HAXB 3O96A 5JHHA 5DI9B 4B6HA 5J3YA 1H10A 4A5KA 4KHOA 2N23A 2DHJA 4HB3B 4KAXB 1FB8A 1U27A 1V88A 3FEHA 1V5UA 2Z0PA 1TXDA 4WVFB 3TVVA 2RUKB 2Z0OA 4HATB 1NI2A 4MY6A 2D9XA 4HB0B 3RCPA 1MPHA 5FI0A 2K2UA 2J0MA 5KQ1A 2MWNB 1V89A 2R0DA 1MK7B 4IAPA 4ZRJA 1ISNA 3VOQA 1SGHA 3GYOA 3QWMA 1BAKA 4HB2B 3A98B 1FHOA 4EKUA 2DN6A 2EC1A 4TKNA 1GC7A 1V5PA 1UEFA 1NU2A 2YRYA 1P5TA 4K2OA 2DKPA 2D4QA 3GYPA 1X1FA 4DX8A 5J3TA 2CY5A 2V76A 1I7AA 1TQZA 2MFQA 2X18A 1J0WA 3SUZA 2DYNA 4A6HA 1DYNA 3UZTA 4KHBB 1FOEA 3D8FA 1PLSA 3CIKA 3FSSA 1DROA 2HE7A 2COFA 1OMWA 2CODA 2IYBA 5HE0A 1EF1A 2AL6A 2LYDA 1WGUA 4YL8A 1V61A 1XX0A 2YS5A 3U7DA 3SNHA 1Y19B 1V5MA 2MDXA 1EVHA 3PVLA 2ROVA 3ODXA 3SO6A 1AQCA 5HE2A 1P3RA 1UNRA 5DHFB 1XD4A 3T06A 2EMTA 3P7ZA 2YS3A 4DX90 5LOPB 1MKEA 3VIAA 1PMSA 2OTXA 3SYXA 4GMVA 5DIFB 3PP2A 3AJ4A 5D27A 3TCAA 2JP2A 3A8PA 1ZVRA 4ZRIA 4MT7A 3TW1A 2D11A 3ZDTA 4K81A 2YT1A 2D2QA 4HAVB 3D8DA 1XODA 2COCA 4GN1A 4KVGB 3V5WA 4HAUB 1DDMA 4HHVA 4PNKA 1IRSA 1WJMA 5GOWB 4IFSA 1Y5OA 2GJYA 1DDWA 3ODWA 5D3XA 2Y8FA 3MDBC 2UZSA 1FGZA 1U5EA 1FGYA 2ELBA 3IVFA 1QQGA 2IFSA 1EAZA 2ADZA 3KZ1A 3PVUA 2R09A 1KZ7A 1X1GA 1UPQA 5CLLB 4ZRKA 3DXEA 2I5FA 2CY4A 3PVWA 2D9YA 1MIXA 4PQ0A 2I1JA 1K5GB 3MPXA 1U5GA 2D9ZA 4Z2MB 2VRWB 3HW2B 1KI1B 2Q13A 1GC6A 4YONA 5D3YA 1BWNA 4GPTB 2DHKA 2BCJA 3X23A 2KUPA 1E5WA 2KCJA 2I1KA 2DX5A 1UNPA 2DA0A 3TFMA 5C79A 1NTYA 4GZUA 3AU4A 2FJLA 1UNQA 3QIJA 3D8EA 2UZRA 2I5CA 2ROZB 4K2PA 1FAOA 5HE1A 3PG7A 4F7UP 1DBHA 5FI1A 1FHWA 4GMXB 2D9VA 2D9WA 1ZC4B 2W2WA 3DXCA 1ZM0A 3ULBA 3KRWA 1NTVA 1BTKA 2LKOA 3WYFB 1U5DA 1P6SA 2DHIA 1W1DA 1KZGA 2H7DA 3G9WA 2H7EA 1WG7A 2YSZA 1ZC3B 2RNRB 4Z2NA 1SHCA 5D3VA 4BBKA 2COAA 5DHAB 1LW3A 4XWXA 1X11A 1M7RA 2L1CA 2P0HA 2W2XD 2NMBA 3SV1A 2HTHB 2YS1A 3TO1A 5JHGA 3M1IB 2DFKA 4WSFA 1BTNA 2LOZA 1U5FA 2P8VA 2KGXB 5DH9B 2RVBB 3AU5A 3BJIA 3ODOA 3N7CA 1H4RA 4HDOA 3DXDA 3LJUX 5CLQB 1MIZB 2M38A 1ZSQA 1RJ2A 1RRPB 1W1GA 2K2JA 5HE3A 2DX1A 4CHJA 2YF0A 4A6FB 2J59M 2AEHA 2PZ1A 2J0JA 5KQ4A 1DDVA 1W1HA 2LG1A 5LONB 1EGXA 5J3QA 3U8ZA 1N3HA 1I2HA 4KHAA 3F0WA
chains in the Genus database with same CATH superfamily
2YT0A 2RGNB 4D6WA 2VKIA 4A6FA 5M4YB 2VSZA 2D10A 1OY2A 1X86A 3PEGA 5D3WA 2MKRA 2EJ8A 2DKQA 4D0NB 1XR0B 1TJ6A 1WI1A 3NSUA 1Q67A 3KSYA 4Y94A 2G35A 2Z59A 2LOXA 5JP4A 1UPRA 3PZDA 2RSGA 1T77A 4C0AA 4HAYB 1MAIA 1K5DB 3P6AA 4QJ5B 3HSAA 3QBVB 2E2XA 2CRFA 3CXBB 2EMSA 2Z0QA 4NSWA 2Y7BA 3ML4A 4EMOA 4DXAB 2DLWA 1M7EA 4IOYX 5JLJB 3F5RA 2J0KA 1U2BA 2GS0A 1WJ1A 2GCLA 2P0FA 4A6KA 2QKMA 4K17A 3KRXA 4CHMA 5L81A 4F7GA 3A8QA 4EJNA 2DTCA 5C16A 4NY0A 2ZPYA 4HAZB 4GXBA 4TYZA 4HDQA 2XQNM 4DIXA 2YVCA 3BINA 1LB1A 1GG3A 2CAYA 4DBBA 1XKEA 2OQBA 2K00A 2QKLA 2W2XC 1PFJA 2KUQA 2M14A 3HK0A 5C5BB 2LULA 3KY9A 4HAWB 4WJ7A 4H8SA 2L2IA 5C6RA 2P0DA 1MI1A 4HB4B 1Z87A 2UVMA 2N0YA 3FM8C 5KCVA 2RLOA 4F7HA 1WGQA 1WVHA 4L6EA 2NZ8B 1AWEA 4MK0A 1U29A 5IRSA 3WA0A 2KIEA 3HQCA 1X05A 5C5BA 2DYQA 3HIEA 3ULCA 1J19A 5EFXA 1QC6A 3FVCA 1FHXA 2ELAA 3NWAA 3PSCA 1B55A 1XCGA 3ZVRA 4OT1A 1MK9B 4P7IA 1OQNA 3OANA 2GCJA 2Y8GA 4CYEA 4HAXB 3U12A 2FJUB 3O96A 5JHHA 5DI9B 4B6HA 5J3YA 1H10A 5LG4B 4A5KA 4KHOA 2N23A 2DHJA 4HB3B 4KAXB 3NWFA 1FB8A 1U27A 1V88A 3FEHA 1V5UA 2Z0PA 1TXDA 4WVFB 3TVVA 2RUKB 2Z0OA 4HATB 1NI2A 4MY6A 2D9XA 4HB0B 3RCPA 1MPHA 5FI0A 2K2UA 2J0MA 5KQ1A 2MWNB 1V89A 2R0DA 1MK7B 4IAPA 4ZRJA 1ISNA 3VOQA 1SGHA 3GYOA 3QWMA 1BAKA 4HB2B 3A98B 1FHOA 2ZKMX 4EKUA 2DN6A 2EC1A 4TKNA 1GC7A 1V5PA 1UEFA 1NU2A 2YRYA 1P5TA 4K2OA 2DKPA 2Z14A 2D4QA 3GYPA 3B77A 1X1FA 4DX8A 5J3TA 2CY5A 2V76A 1I7AA 1TQZA 2MFQA 2X18A 1J0WA 3SUZA 2DYNA 4A6HA 1DYNA 3UZTA 4KHBB 3OHMB 1FOEA 3D8FA 1PLSA 3CIKA 3FSSA 1DROA 2HE7A 2COFA 1OMWA 2Z13A 2CODA 4QJ3B 2IYBA 5HE0A 1EF1A 2AL6A 2LYDA 1WGUA 4YL8A 1V61A 1XX0A 2YS5A 3U7DA 3SNHA 4KHBA 1Y19B 1V5MA 2MDXA 1EVHA 3PVLA 2ROVA 3ODXA 3SO6A 1AQCA 5HE2A 1P3RA 4QJ4B 1UNRA 5DHFB 1XD4A 3T06A 2EMTA 3P7ZA 2YS3A 5I2MA 4DX90 5LOPB 1MKEA 3VIAA 1PMSA 2OTXA 3SYXA 4GMVA 5DIFB 3PP2A 3AJ4A 5D27A 3TCAA 2JP2A 3A8PA 1ZVRA 4ZRIA 4MT7A 3TW1A 2D11A 3ZDTA 4K81A 2Z4DA 2YT1A 2D2QA 4HAVB 3D8DA 1XODA 1ZYIA 2COCA 4HSIA 4GN1A 4KVGB 3V5WA 4HAUB 1DDMA 4HHVA 4PNKA 1IRSA 1WJMA 5GOWB 4IFSA 1Y5OA 2GJYA 1DDWA 3ODWA 5D3XA 2Y8FA 3MDBC 2UZSA 1FGZA 1U5EA 1FGYA 2ELBA 3IVFA 1QQGA 2IFSA 1EAZA 2ADZA 3KZ1A 3PVUA 2R09A 1KZ7A 1X1GA 4QXAB 1UPQA 5CLLB 2YT2A 4ZRKA 3DXEA 2I5FA 2CY4A 3PVWA 2D9YA 2R2YA 1MIXA 4PQ0A 4CSQA 2I1JA 1K5GB 3MPXA 1U5GA 2D9ZA 3NWDA 4Z2MB 2VRWB 3HW2B 1KI1B 2Q13A 4OSNA 1GC6A 4YONA 5D3YA 2K8EA 1BWNA 4GPTB 2DHKA 2BCJA 3X23A 2KUPA 1E5WA 2KIGA 2KCJA 2I1KA 2DX5A 1UNPA 2DA0A 3TFMA 5C79A 1NTYA 4GZUA 3AU4A 2FJLA 1UNQA 3QIJA 4GOUA 3D8EA 2UZRA 2K49A 2I5CA 2ROZB 4K2PA 1FAOA 4L1RA 5HE1A 3PG7A 4F7UP 1DBHA 5FI1A 1FHWA 4GMXB 2D9VA 2D9WA 1ZC4B 2W2WA 3DXCA 1ZM0A 3ULBA 3KRWA 1NTVA 1BTKA 2LKOA 4GNKB 3WYFB 1U5DA 1P6SA 2DHIA 1W1DA 3NW8A 5I2SA 1KZGA 2H7DA 3G9WA 2H7EA 1WG7A 2YSZA 1ZC3B 2RNRB 4Z2NA 1SHCA 5D3VA 4BBKA 2COAA 2NBVA 5DHAB 1LW3A 3DCXA 4XWXA 1X11A 1M7RA 2L1CA 2P0HA 2W2XD 2NMBA 3SV1A 2HTHB 2YS1A 3TO1A 5JHGA 3M1IB 2RRFA 2DFKA 4WSFA 1BTNA 2LOZA 1U5FA 2P8VA 2KGXB 5DH9B 2RVBB 3AU5A 3BJIA 3ODOA 3N7CA 2GUMA 1H4RA 4HDOA 3DXDA 3LJUX 5CLQB 1MIZB 2M38A 1ZSQA 1RJ2A 1RRPB 1W1GA 2K2JA 5HE3A 2DX1A 3A58A 4CHJA 2YF0A 4A6FB 2J59M 2AEHA 2PZ1A 2J0JA 5KQ4A 2KR0A 1DDVA 1W1HA 2LG1A 5LONB 1EGXA 5J3QA 3U8ZA 1N3HA 1I2HA 4KHAA 3F0WA
chains in the Genus database with same CATH topology
2YT0A 2RGNB 2VKIA 4A6FA 2VSZA 2D10A 1OY2A 1X86A 3PEGA 5D3WA 2MKRA 2EJ8A 2DKQA 4D0NB 1XR0B 1TJ6A 1WI1A 3NSUA 1Q67A 3KSYA 4Y94A 2G35A 2LOXA 5JP4A 1UPRA 3PZDA 2RSGA 4C0AA 4HAYB 1MAIA 1K5DB 3P6AA 3QBVB 2E2XA 2CRFA 3CXBB 2EMSA 2Z0QA 4NSWA 2Y7BA 3ML4A 4EMOA 4DXAB 2DLWA 1M7EA 4IOYX 5JLJB 3F5RA 2J0KA 1U2BA 2GS0A 1WJ1A 2GCLA 2P0FA 4A6KA 2QKMA 4K17A 3KRXA 4CHMA 5L81A 4F7GA 3A8QA 4EJNA 2DTCA 5C16A 4NY0A 2ZPYA 4HAZB 4GXBA 4TYZA 4HDQA 2XQNM 2YVCA 3BINA 1LB1A 1GG3A 2CAYA 4DBBA 1XKEA 2OQBA 2K00A 2QKLA 2W2XC 1PFJA 2M14A 3HK0A 5C5BB 2LULA 3KY9A 4HAWB 4WJ7A 4H8SA 2L2IA 5C6RA 2P0DA 4HB4B 1Z87A 2UVMA 2N0YA 3FM8C 5KCVA 2RLOA 4F7HA 1WGQA 1WVHA 4L6EA 2NZ8B 1AWEA 4MK0A 1U29A 3WA0A 3HQCA 1X05A 5C5BA 2DYQA 3ULCA 1J19A 5EFXA 1QC6A 1FHXA 2ELAA 3PSCA 1B55A 1XCGA 3ZVRA 1MK9B 4P7IA 1OQNA 3OANA 2GCJA 2Y8GA 4CYEA 4HAXB 3O96A 5JHHA 5DI9B 4B6HA 5J3YA 1H10A 4A5KA 4KHOA 2N23A 2DHJA 4HB3B 4KAXB 1FB8A 1U27A 1V88A 3FEHA 1V5UA 2Z0PA 1TXDA 4WVFB 3TVVA 2RUKB 2Z0OA 4HATB 1NI2A 4MY6A 2D9XA 4HB0B 3RCPA 1MPHA 5FI0A 2K2UA 2J0MA 5KQ1A 2MWNB 1V89A 2R0DA 1MK7B 4IAPA 4ZRJA 1ISNA 3VOQA 1SGHA 3GYOA 3QWMA 1BAKA 4HB2B 3A98B 1FHOA 4EKUA 2DN6A 2EC1A 4TKNA 1GC7A 1V5PA 1UEFA 1NU2A 2YRYA 1P5TA 4K2OA 2DKPA 2D4QA 3GYPA 1X1FA 4DX8A 5J3TA 2CY5A 2V76A 1I7AA 1TQZA 2MFQA 2X18A 1J0WA 3SUZA 2DYNA 4A6HA 1DYNA 3UZTA 4KHBB 1FOEA 3D8FA 1PLSA 3CIKA 3FSSA 1DROA 2HE7A 2COFA 1OMWA 2CODA 2IYBA 5HE0A 1EF1A 2AL6A 2LYDA 1WGUA 4YL8A 1V61A 1XX0A 2YS5A 3U7DA 3SNHA 1Y19B 1V5MA 2MDXA 1EVHA 3PVLA 2ROVA 3ODXA 3SO6A 1AQCA 5HE2A 1P3RA 1UNRA 5DHFB 1XD4A 3T06A 2EMTA 3P7ZA 2YS3A 4DX90 5LOPB 1MKEA 3VIAA 1PMSA 2OTXA 3SYXA 4GMVA 5DIFB 3PP2A 3AJ4A 5D27A 3TCAA 2JP2A 3A8PA 1ZVRA 4ZRIA 4MT7A 3TW1A 2D11A 3ZDTA 4K81A 2YT1A 2D2QA 4HAVB 3D8DA 1XODA 2COCA 4GN1A 4KVGB 3V5WA 4HAUB 1DDMA 4HHVA 4PNKA 1IRSA 1WJMA 5GOWB 4IFSA 1Y5OA 2GJYA 1DDWA 3ODWA 5D3XA 2Y8FA 3MDBC 2UZSA 1FGZA 1U5EA 1FGYA 2ELBA 3IVFA 1QQGA 2IFSA 1EAZA 2ADZA 3KZ1A 3PVUA 2R09A 1KZ7A 1X1GA 1UPQA 5CLLB 4ZRKA 3DXEA 2I5FA 2CY4A 3PVWA 2D9YA 1MIXA 4PQ0A 2I1JA 1K5GB 3MPXA 1U5GA 2D9ZA 4Z2MB 2VRWB 3HW2B 1KI1B 2Q13A 1GC6A 4YONA 5D3YA 1BWNA 4GPTB 2DHKA 2BCJA 3X23A 2KUPA 1E5WA 2KCJA 2I1KA 2DX5A 1UNPA 2DA0A 3TFMA 5C79A 1NTYA 4GZUA 3AU4A 2FJLA 1UNQA 3QIJA 3D8EA 2UZRA 2I5CA 2ROZB 4K2PA 1FAOA 5HE1A 3PG7A 4F7UP 1DBHA 5FI1A 1FHWA 4GMXB 2D9VA 2D9WA 1ZC4B 2W2WA 3DXCA 1ZM0A 3ULBA 3KRWA 1NTVA 1BTKA 2LKOA 3WYFB 1U5DA 1P6SA 2DHIA 1W1DA 1KZGA 2H7DA 3G9WA 2H7EA 1WG7A 2YSZA 1ZC3B 2RNRB 4Z2NA 1SHCA 5D3VA 4BBKA 2COAA 5DHAB 1LW3A 4XWXA 1X11A 1M7RA 2L1CA 2P0HA 2W2XD 2NMBA 3SV1A 2HTHB 2YS1A 3TO1A 5JHGA 3M1IB 2DFKA 4WSFA 1BTNA 2LOZA 1U5FA 2P8VA 2KGXB 5DH9B 2RVBB 3AU5A 3BJIA 3ODOA 3N7CA 1H4RA 4HDOA 3DXDA 3LJUX 5CLQB 1MIZB 2M38A 1ZSQA 1RJ2A 1RRPB 1W1GA 2K2JA 5HE3A 2DX1A 4CHJA 2YF0A 4A6FB 2J59M 2AEHA 2PZ1A 2J0JA 5KQ4A 1DDVA 1W1HA 2LG1A 5LONB 1EGXA 5J3QA 3U8ZA 1N3HA 1I2HA 4KHAA 3F0WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YT0 A;  2RGN B;  2VKI A;  4A6F A;  2VSZ A;  2D10 A;  1OY2 A;  1X86 A;  3PEG A;  5D3W A;  2MKR A;  2EJ8 A;  2DKQ A;  4D0N B;  1XR0 B;  1TJ6 A;  1WI1 A;  3NSU A;  1Q67 A;  3KSY A;  4Y94 A;  2G35 A;  2LOX A;  5JP4 A;  1UPR A;  3PZD A;  2RSG A;  4C0A A;  4HAY B;  1MAI A;  1K5D B;  3P6A A;  3QBV B;  2E2X A;  2CRF A;  3CXB B;  2EMS A;  2Z0Q A;  4NSW A;  2Y7B A;  3ML4 A;  4EMO A;  4DXA B;  2DLW A;  1M7E A;  4IOY X;  5JLJ B;  3F5R A;  2J0K A;  1U2B A;  2GS0 A;  1WJ1 A;  2GCL A;  2P0F A;  4A6K A;  2QKM A;  4K17 A;  3KRX A;  4CHM A;  5L81 A;  4F7G A;  3A8Q A;  4EJN A;  2DTC A;  5C16 A;  4NY0 A;  2ZPY A;  4HAZ B;  4GXB A;  4TYZ A;  4HDQ A;  2XQN M;  2YVC A;  3BIN A;  1LB1 A;  1GG3 A;  2CAY A;  4DBB A;  1XKE A;  2OQB A;  2K00 A;  2QKL A;  2W2X C;  1PFJ A;  2M14 A;  3HK0 A;  5C5B B;  2LUL A;  3KY9 A;  4HAW B;  4WJ7 A;  4H8S A;  2L2I A;  5C6R A;  2P0D A;  4HB4 B;  1Z87 A;  2UVM A;  2N0Y A;  3FM8 C;  5KCV A;  2RLO A;  4F7H A;  1WGQ A;  1WVH A;  4L6E A;  2NZ8 B;  1AWE A;  4MK0 A;  1U29 A;  3WA0 A;  3HQC A;  1X05 A;  5C5B A;  2DYQ A;  3ULC A;  1J19 A;  5EFX A;  1QC6 A;  1FHX A;  2ELA A;  3PSC A;  1B55 A;  1XCG A;  3ZVR A;  1MK9 B;  4P7I A;  1OQN A;  3OAN A;  2GCJ A;  2Y8G A;  4CYE A;  4HAX B;  3O96 A;  5JHH A;  5DI9 B;  4B6H A;  5J3Y A;  1H10 A;  4A5K A;  4KHO A;  2N23 A;  2DHJ A;  4HB3 B;  4KAX B;  1FB8 A;  1U27 A;  1V88 A;  3FEH A;  1V5U A;  2Z0P A;  1TXD A;  4WVF B;  3TVV A;  2RUK B;  2Z0O A;  4HAT B;  1NI2 A;  4MY6 A;  2D9X A;  4HB0 B;  3RCP A;  1MPH A;  5FI0 A;  2K2U A;  2J0M A;  5KQ1 A;  2MWN B;  1V89 A;  2R0D A;  1MK7 B;  4IAP A;  4ZRJ A;  1ISN A;  3VOQ A;  1SGH A;  3GYO A;  3QWM A;  1BAK A;  4HB2 B;  3A98 B;  1FHO A;  4EKU A;  2DN6 A;  2EC1 A;  4TKN A;  1GC7 A;  1V5P A;  1UEF A;  1NU2 A;  2YRY A;  1P5T A;  4K2O A;  2DKP A;  2D4Q A;  3GYP A;  1X1F A;  4DX8 A;  5J3T A;  2CY5 A;  2V76 A;  1I7A A;  1TQZ A;  2MFQ A;  2X18 A;  1J0W A;  3SUZ A;  2DYN A;  4A6H A;  1DYN A;  3UZT A;  4KHB B;  1FOE A;  3D8F A;  1PLS A;  3CIK A;  3FSS A;  1DRO A;  2HE7 A;  2COF A;  1OMW A;  2COD A;  2IYB A;  5HE0 A;  1EF1 A;  2AL6 A;  2LYD A;  1WGU A;  4YL8 A;  1V61 A;  1XX0 A;  2YS5 A;  3U7D A;  3SNH A;  1Y19 B;  1V5M A;  2MDX A;  1EVH A;  3PVL A;  2ROV A;  3ODX A;  3SO6 A;  1AQC A;  5HE2 A;  1P3R A;  1UNR A;  5DHF B;  1XD4 A;  3T06 A;  2EMT A;  3P7Z A;  2YS3 A;  4DX9 0;  5LOP B;  1MKE A;  3VIA A;  1PMS A;  2OTX A;  3SYX A;  4GMV A;  5DIF B;  3PP2 A;  3AJ4 A;  5D27 A;  3TCA A;  2JP2 A;  3A8P A;  1ZVR A;  4ZRI A;  4MT7 A;  3TW1 A;  2D11 A;  3ZDT A;  4K81 A;  2YT1 A;  2D2Q A;  4HAV B;  3D8D A;  1XOD A;  2COC A;  4GN1 A;  4KVG B;  3V5W A;  4HAU B;  1DDM A;  4HHV A;  4PNK A;  1IRS A;  1WJM A;  5GOW B;  4IFS A;  1Y5O A;  2GJY A;  1DDW A;  3ODW A;  5D3X A;  2Y8F A;  3MDB C;  2UZS A;  1FGZ A;  1U5E A;  1FGY A;  2ELB A;  3IVF A;  1QQG A;  2IFS A;  1EAZ A;  2ADZ A;  3KZ1 A;  3PVU A;  2R09 A;  1KZ7 A;  1X1G A;  1UPQ A;  5CLL B;  4ZRK A;  3DXE A;  2I5F A;  2CY4 A;  3PVW A;  2D9Y A;  1MIX A;  4PQ0 A;  2I1J A;  1K5G B;  3MPX A;  1U5G A;  2D9Z A;  4Z2M B;  2VRW B;  3HW2 B;  1KI1 B;  2Q13 A;  1GC6 A;  4YON A;  5D3Y A;  1BWN A;  4GPT B;  2DHK A;  2BCJ A;  3X23 A;  2KUP A;  1E5W A;  2KCJ A;  2I1K A;  2DX5 A;  1UNP A;  2DA0 A;  3TFM A;  5C79 A;  1NTY A;  4GZU A;  3AU4 A;  2FJL A;  1UNQ A;  3QIJ A;  3D8E A;  2UZR A;  2I5C A;  2ROZ B;  4K2P A;  1FAO A;  5HE1 A;  3PG7 A;  4F7U P;  1DBH A;  5FI1 A;  1FHW A;  4GMX B;  2D9V A;  2D9W A;  1ZC4 B;  2W2W A;  3DXC A;  1ZM0 A;  3ULB A;  3KRW A;  1NTV A;  1BTK A;  2LKO A;  3WYF B;  1U5D A;  1P6S A;  2DHI A;  1W1D A;  1KZG A;  2H7D A;  3G9W A;  2H7E A;  1WG7 A;  2YSZ A;  1ZC3 B;  2RNR B;  4Z2N A;  1SHC A;  5D3V A;  4BBK A;  2COA A;  5DHA B;  1LW3 A;  4XWX A;  1X11 A;  1M7R A;  2L1C A;  2P0H A;  2W2X D;  2NMB A;  3SV1 A;  2HTH B;  2YS1 A;  3TO1 A;  5JHG A;  3M1I B;  2DFK A;  4WSF A;  1BTN A;  2LOZ A;  1U5F A;  2P8V A;  2KGX B;  5DH9 B;  2RVB B;  3AU5 A;  3BJI A;  3ODO A;  3N7C A;  1H4R A;  4HDO A;  3DXD A;  3LJU X;  5CLQ B;  1MIZ B;  2M38 A;  1ZSQ A;  1RJ2 A;  1RRP B;  1W1G A;  2K2J A;  5HE3 A;  2DX1 A;  4CHJ A;  2YF0 A;  4A6F B;  2J59 M;  2AEH A;  2PZ1 A;  2J0J A;  5KQ4 A;  1DDV A;  1W1H A;  2LG1 A;  5LON B;  1EGX A;  5J3Q A;  3U8Z A;  1N3H A;  1I2H A;  4KHA A;  3F0W A; 
#chains in the Genus database with same CATH topology
 2YT0 A;  2RGN B;  4D6W A;  2VKI A;  4A6F A;  5M4Y B;  2VSZ A;  2D10 A;  1OY2 A;  1X86 A;  3PEG A;  5D3W A;  2MKR A;  2EJ8 A;  2DKQ A;  4D0N B;  1XR0 B;  1TJ6 A;  1WI1 A;  3NSU A;  1Q67 A;  3KSY A;  4Y94 A;  2G35 A;  2Z59 A;  2LOX A;  5JP4 A;  1UPR A;  3PZD A;  2RSG A;  1T77 A;  4C0A A;  4HAY B;  1MAI A;  1K5D B;  3P6A A;  4QJ5 B;  3HSA A;  3QBV B;  2E2X A;  2CRF A;  3CXB B;  2EMS A;  2Z0Q A;  4NSW A;  2Y7B A;  3ML4 A;  4EMO A;  4DXA B;  2DLW A;  1M7E A;  4IOY X;  5JLJ B;  3F5R A;  2J0K A;  1U2B A;  2GS0 A;  1WJ1 A;  2GCL A;  2P0F A;  4A6K A;  2QKM A;  4K17 A;  3KRX A;  4CHM A;  5L81 A;  4F7G A;  3A8Q A;  4EJN A;  2DTC A;  5C16 A;  4NY0 A;  2ZPY A;  4HAZ B;  4GXB A;  4TYZ A;  4HDQ A;  2XQN M;  4DIX A;  2YVC A;  3BIN A;  1LB1 A;  1GG3 A;  2CAY A;  4DBB A;  1XKE A;  2OQB A;  2K00 A;  2QKL A;  2W2X C;  1PFJ A;  2KUQ A;  2M14 A;  3HK0 A;  5C5B B;  2LUL A;  3KY9 A;  4HAW B;  4WJ7 A;  4H8S A;  2L2I A;  5C6R A;  2P0D A;  1MI1 A;  4HB4 B;  1Z87 A;  2UVM A;  2N0Y A;  3FM8 C;  5KCV A;  2RLO A;  4F7H A;  1WGQ A;  1WVH A;  4L6E A;  2NZ8 B;  1AWE A;  4MK0 A;  1U29 A;  5IRS A;  3WA0 A;  2KIE A;  3HQC A;  1X05 A;  5C5B A;  2DYQ A;  3HIE A;  3ULC A;  1J19 A;  5EFX A;  1QC6 A;  3FVC A;  1FHX A;  2ELA A;  3NWA A;  3PSC A;  1B55 A;  1XCG A;  3ZVR A;  4OT1 A;  1MK9 B;  4P7I A;  1OQN A;  3OAN A;  2GCJ A;  2Y8G A;  4CYE A;  4HAX B;  3U12 A;  2FJU B;  3O96 A;  5JHH A;  5DI9 B;  4B6H A;  5J3Y A;  1H10 A;  5LG4 B;  4A5K A;  4KHO A;  2N23 A;  2DHJ A;  4HB3 B;  4KAX B;  3NWF A;  1FB8 A;  1U27 A;  1V88 A;  3FEH A;  1V5U A;  2Z0P A;  1TXD A;  4WVF B;  3TVV A;  2RUK B;  2Z0O A;  4HAT B;  1NI2 A;  4MY6 A;  2D9X A;  4HB0 B;  3RCP A;  1MPH A;  5FI0 A;  2K2U A;  2J0M A;  5KQ1 A;  2MWN B;  1V89 A;  2R0D A;  1MK7 B;  4IAP A;  4ZRJ A;  1ISN A;  3VOQ A;  1SGH A;  3GYO A;  3QWM A;  1BAK A;  4HB2 B;  3A98 B;  1FHO A;  2ZKM X;  4EKU A;  2DN6 A;  2EC1 A;  4TKN A;  1GC7 A;  1V5P A;  1UEF A;  1NU2 A;  2YRY A;  1P5T A;  4K2O A;  2DKP A;  2Z14 A;  2D4Q A;  3GYP A;  3B77 A;  1X1F A;  4DX8 A;  5J3T A;  2CY5 A;  2V76 A;  1I7A A;  1TQZ A;  2MFQ A;  2X18 A;  1J0W A;  3SUZ A;  2DYN A;  4A6H A;  1DYN A;  3UZT A;  4KHB B;  3OHM B;  1FOE A;  3D8F A;  1PLS A;  3CIK A;  3FSS A;  1DRO A;  2HE7 A;  2COF A;  1OMW A;  2Z13 A;  2COD A;  4QJ3 B;  2IYB A;  5HE0 A;  1EF1 A;  2AL6 A;  2LYD A;  1WGU A;  4YL8 A;  1V61 A;  1XX0 A;  2YS5 A;  3U7D A;  3SNH A;  4KHB A;  1Y19 B;  1V5M A;  2MDX A;  1EVH A;  3PVL A;  2ROV A;  3ODX A;  3SO6 A;  1AQC A;  5HE2 A;  1P3R A;  4QJ4 B;  1UNR A;  5DHF B;  1XD4 A;  3T06 A;  2EMT A;  3P7Z A;  2YS3 A;  5I2M A;  4DX9 0;  5LOP B;  1MKE A;  3VIA A;  1PMS A;  2OTX A;  3SYX A;  4GMV A;  5DIF B;  3PP2 A;  3AJ4 A;  5D27 A;  3TCA A;  2JP2 A;  3A8P A;  1ZVR A;  4ZRI A;  4MT7 A;  3TW1 A;  2D11 A;  3ZDT A;  4K81 A;  2Z4D A;  2YT1 A;  2D2Q A;  4HAV B;  3D8D A;  1XOD A;  1ZYI A;  2COC A;  4HSI A;  4GN1 A;  4KVG B;  3V5W A;  4HAU B;  1DDM A;  4HHV A;  4PNK A;  1IRS A;  1WJM A;  5GOW B;  4IFS A;  1Y5O A;  2GJY A;  1DDW A;  3ODW A;  5D3X A;  2Y8F A;  3MDB C;  2UZS A;  1FGZ A;  1U5E A;  1FGY A;  2ELB A;  3IVF A;  1QQG A;  2IFS A;  1EAZ A;  2ADZ A;  3KZ1 A;  3PVU A;  2R09 A;  1KZ7 A;  1X1G A;  4QXA B;  1UPQ A;  5CLL B;  2YT2 A;  4ZRK A;  3DXE A;  2I5F A;  2CY4 A;  3PVW A;  2D9Y A;  2R2Y A;  1MIX A;  4PQ0 A;  4CSQ A;  2I1J A;  1K5G B;  3MPX A;  1U5G A;  2D9Z A;  3NWD A;  4Z2M B;  2VRW B;  3HW2 B;  1KI1 B;  2Q13 A;  4OSN A;  1GC6 A;  4YON A;  5D3Y A;  2K8E A;  1BWN A;  4GPT B;  2DHK A;  2BCJ A;  3X23 A;  2KUP A;  1E5W A;  2KIG A;  2KCJ A;  2I1K A;  2DX5 A;  1UNP A;  2DA0 A;  3TFM A;  5C79 A;  1NTY A;  4GZU A;  3AU4 A;  2FJL A;  1UNQ A;  3QIJ A;  4GOU A;  3D8E A;  2UZR A;  2K49 A;  2I5C A;  2ROZ B;  4K2P A;  1FAO A;  4L1R A;  5HE1 A;  3PG7 A;  4F7U P;  1DBH A;  5FI1 A;  1FHW A;  4GMX B;  2D9V A;  2D9W A;  1ZC4 B;  2W2W A;  3DXC A;  1ZM0 A;  3ULB A;  3KRW A;  1NTV A;  1BTK A;  2LKO A;  4GNK B;  3WYF B;  1U5D A;  1P6S A;  2DHI A;  1W1D A;  3NW8 A;  5I2S A;  1KZG A;  2H7D A;  3G9W A;  2H7E A;  1WG7 A;  2YSZ A;  1ZC3 B;  2RNR B;  4Z2N A;  1SHC A;  5D3V A;  4BBK A;  2COA A;  2NBV A;  5DHA B;  1LW3 A;  3DCX A;  4XWX A;  1X11 A;  1M7R A;  2L1C A;  2P0H A;  2W2X D;  2NMB A;  3SV1 A;  2HTH B;  2YS1 A;  3TO1 A;  5JHG A;  3M1I B;  2RRF A;  2DFK A;  4WSF A;  1BTN A;  2LOZ A;  1U5F A;  2P8V A;  2KGX B;  5DH9 B;  2RVB B;  3AU5 A;  3BJI A;  3ODO A;  3N7C A;  2GUM A;  1H4R A;  4HDO A;  3DXD A;  3LJU X;  5CLQ B;  1MIZ B;  2M38 A;  1ZSQ A;  1RJ2 A;  1RRP B;  1W1G A;  2K2J A;  5HE3 A;  2DX1 A;  3A58 A;  4CHJ A;  2YF0 A;  4A6F B;  2J59 M;  2AEH A;  2PZ1 A;  2J0J A;  5KQ4 A;  2KR0 A;  1DDV A;  1W1H A;  2LG1 A;  5LON B;  1EGX A;  5J3Q A;  3U8Z A;  1N3H A;  1I2H A;  4KHA A;  3F0W A; 
#chains in the Genus database with same CATH homology
 2YT0 A;  2RGN B;  2VKI A;  4A6F A;  2VSZ A;  2D10 A;  1OY2 A;  1X86 A;  3PEG A;  5D3W A;  2MKR A;  2EJ8 A;  2DKQ A;  4D0N B;  1XR0 B;  1TJ6 A;  1WI1 A;  3NSU A;  1Q67 A;  3KSY A;  4Y94 A;  2G35 A;  2LOX A;  5JP4 A;  1UPR A;  3PZD A;  2RSG A;  4C0A A;  4HAY B;  1MAI A;  1K5D B;  3P6A A;  3QBV B;  2E2X A;  2CRF A;  3CXB B;  2EMS A;  2Z0Q A;  4NSW A;  2Y7B A;  3ML4 A;  4EMO A;  4DXA B;  2DLW A;  1M7E A;  4IOY X;  5JLJ B;  3F5R A;  2J0K A;  1U2B A;  2GS0 A;  1WJ1 A;  2GCL A;  2P0F A;  4A6K A;  2QKM A;  4K17 A;  3KRX A;  4CHM A;  5L81 A;  4F7G A;  3A8Q A;  4EJN A;  2DTC A;  5C16 A;  4NY0 A;  2ZPY A;  4HAZ B;  4GXB A;  4TYZ A;  4HDQ A;  2XQN M;  2YVC A;  3BIN A;  1LB1 A;  1GG3 A;  2CAY A;  4DBB A;  1XKE A;  2OQB A;  2K00 A;  2QKL A;  2W2X C;  1PFJ A;  2M14 A;  3HK0 A;  5C5B B;  2LUL A;  3KY9 A;  4HAW B;  4WJ7 A;  4H8S A;  2L2I A;  5C6R A;  2P0D A;  4HB4 B;  1Z87 A;  2UVM A;  2N0Y A;  3FM8 C;  5KCV A;  2RLO A;  4F7H A;  1WGQ A;  1WVH A;  4L6E A;  2NZ8 B;  1AWE A;  4MK0 A;  1U29 A;  3WA0 A;  3HQC A;  1X05 A;  5C5B A;  2DYQ A;  3ULC A;  1J19 A;  5EFX A;  1QC6 A;  1FHX A;  2ELA A;  3PSC A;  1B55 A;  1XCG A;  3ZVR A;  1MK9 B;  4P7I A;  1OQN A;  3OAN A;  2GCJ A;  2Y8G A;  4CYE A;  4HAX B;  3O96 A;  5JHH A;  5DI9 B;  4B6H A;  5J3Y A;  1H10 A;  4A5K A;  4KHO A;  2N23 A;  2DHJ A;  4HB3 B;  4KAX B;  1FB8 A;  1U27 A;  1V88 A;  3FEH A;  1V5U A;  2Z0P A;  1TXD A;  4WVF B;  3TVV A;  2RUK B;  2Z0O A;  4HAT B;  1NI2 A;  4MY6 A;  2D9X A;  4HB0 B;  3RCP A;  1MPH A;  5FI0 A;  2K2U A;  2J0M A;  5KQ1 A;  2MWN B;  1V89 A;  2R0D A;  1MK7 B;  4IAP A;  4ZRJ A;  1ISN A;  3VOQ A;  1SGH A;  3GYO A;  3QWM A;  1BAK A;  4HB2 B;  3A98 B;  1FHO A;  4EKU A;  2DN6 A;  2EC1 A;  4TKN A;  1GC7 A;  1V5P A;  1UEF A;  1NU2 A;  2YRY A;  1P5T A;  4K2O A;  2DKP A;  2D4Q A;  3GYP A;  1X1F A;  4DX8 A;  5J3T A;  2CY5 A;  2V76 A;  1I7A A;  1TQZ A;  2MFQ A;  2X18 A;  1J0W A;  3SUZ A;  2DYN A;  4A6H A;  1DYN A;  3UZT A;  4KHB B;  1FOE A;  3D8F A;  1PLS A;  3CIK A;  3FSS A;  1DRO A;  2HE7 A;  2COF A;  1OMW A;  2COD A;  2IYB A;  5HE0 A;  1EF1 A;  2AL6 A;  2LYD A;  1WGU A;  4YL8 A;  1V61 A;  1XX0 A;  2YS5 A;  3U7D A;  3SNH A;  1Y19 B;  1V5M A;  2MDX A;  1EVH A;  3PVL A;  2ROV A;  3ODX A;  3SO6 A;  1AQC A;  5HE2 A;  1P3R A;  1UNR A;  5DHF B;  1XD4 A;  3T06 A;  2EMT A;  3P7Z A;  2YS3 A;  4DX9 0;  5LOP B;  1MKE A;  3VIA A;  1PMS A;  2OTX A;  3SYX A;  4GMV A;  5DIF B;  3PP2 A;  3AJ4 A;  5D27 A;  3TCA A;  2JP2 A;  3A8P A;  1ZVR A;  4ZRI A;  4MT7 A;  3TW1 A;  2D11 A;  3ZDT A;  4K81 A;  2YT1 A;  2D2Q A;  4HAV B;  3D8D A;  1XOD A;  2COC A;  4GN1 A;  4KVG B;  3V5W A;  4HAU B;  1DDM A;  4HHV A;  4PNK A;  1IRS A;  1WJM A;  5GOW B;  4IFS A;  1Y5O A;  2GJY A;  1DDW A;  3ODW A;  5D3X A;  2Y8F A;  3MDB C;  2UZS A;  1FGZ A;  1U5E A;  1FGY A;  2ELB A;  3IVF A;  1QQG A;  2IFS A;  1EAZ A;  2ADZ A;  3KZ1 A;  3PVU A;  2R09 A;  1KZ7 A;  1X1G A;  1UPQ A;  5CLL B;  4ZRK A;  3DXE A;  2I5F A;  2CY4 A;  3PVW A;  2D9Y A;  1MIX A;  4PQ0 A;  2I1J A;  1K5G B;  3MPX A;  1U5G A;  2D9Z A;  4Z2M B;  2VRW B;  3HW2 B;  1KI1 B;  2Q13 A;  1GC6 A;  4YON A;  5D3Y A;  1BWN A;  4GPT B;  2DHK A;  2BCJ A;  3X23 A;  2KUP A;  1E5W A;  2KCJ A;  2I1K A;  2DX5 A;  1UNP A;  2DA0 A;  3TFM A;  5C79 A;  1NTY A;  4GZU A;  3AU4 A;  2FJL A;  1UNQ A;  3QIJ A;  3D8E A;  2UZR A;  2I5C A;  2ROZ B;  4K2P A;  1FAO A;  5HE1 A;  3PG7 A;  4F7U P;  1DBH A;  5FI1 A;  1FHW A;  4GMX B;  2D9V A;  2D9W A;  1ZC4 B;  2W2W A;  3DXC A;  1ZM0 A;  3ULB A;  3KRW A;  1NTV A;  1BTK A;  2LKO A;  3WYF B;  1U5D A;  1P6S A;  2DHI A;  1W1D A;  1KZG A;  2H7D A;  3G9W A;  2H7E A;  1WG7 A;  2YSZ A;  1ZC3 B;  2RNR B;  4Z2N A;  1SHC A;  5D3V A;  4BBK A;  2COA A;  5DHA B;  1LW3 A;  4XWX A;  1X11 A;  1M7R A;  2L1C A;  2P0H A;  2W2X D;  2NMB A;  3SV1 A;  2HTH B;  2YS1 A;  3TO1 A;  5JHG A;  3M1I B;  2DFK A;  4WSF A;  1BTN A;  2LOZ A;  1U5F A;  2P8V A;  2KGX B;  5DH9 B;  2RVB B;  3AU5 A;  3BJI A;  3ODO A;  3N7C A;  1H4R A;  4HDO A;  3DXD A;  3LJU X;  5CLQ B;  1MIZ B;  2M38 A;  1ZSQ A;  1RJ2 A;  1RRP B;  1W1G A;  2K2J A;  5HE3 A;  2DX1 A;  4CHJ A;  2YF0 A;  4A6F B;  2J59 M;  2AEH A;  2PZ1 A;  2J0J A;  5KQ4 A;  1DDV A;  1W1H A;  2LG1 A;  5LON B;  1EGX A;  5J3Q A;  3U8Z A;  1N3H A;  1I2H A;  4KHA A;  3F0W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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