5EFXA

Crystal structure of rho gtpase regulator
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
144
structure length
144
Chain Sequence
GARLQEIYNRMDPRAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFLISAAPPEMYEVHTASRDDRSTWIRVIQQSVRTCPSREDFPLI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of hGEF-H1 PH domain provides insight into incapability in phosphoinositide binding
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Rho guanine nucleotide exchange factor 2
total genus 36
structure length 144
sequence length 144
ec nomenclature
pdb deposition date 2015-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF17838 PH_16 PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 5efxA00
4KHOA 3KRXA 2PZ1A 3PG7A 1QQGA 1OY2A 2UZSA 2DA0A 4DXAB 1ZC4B 2YRYA 2OQBA 3ODWA 2EC1A 2D9XA 2GCJA 1X11A 1Q67A 3KRWA 3T06A 1KZGA 3CXBB 2M38A 2KCJA 3AU5A 5CLLB 2YT0A 3TFMA 4DBBA 1DDWA 2N23A 2K2JA 1W1HA 1WGUA 4A6FA 1X1FA 3D8FA 3TCAA 3U8ZA 1V5PA 1XODA 5C6RA 1XKEA 2XQNM 4KVGB 1BTKA 3MDBC 4K2OA 1BTNA 1BWNA 1J19A 1TQZA 2CY4A 1X05A 5KQ1A 4NY0A 1I2HA 2L2IA 4MK0A 1RRPB 3TW1A 4EJNA 4F7GA 3RCPA 2X18A 1UNPA 4YONA 2DHJA 1U5EA 2J0JA 2DYNA 2P0DA 1AWEA 3SO6A 2ROVA 1EF1A 2Y8FA 1XX0A 2R09A 1IRSA 1XCGA 1N3HA 2EMTA 2RLOA 2DFKA 1MK9B 5J3YA 1PLSA 5JP4A 1UPRA 1V89A 2YS5A 1WJ1A 3A98B 5LONB 1J0WA 1FOEA 4ZRKA 1H4RA 1AQCA 4XWXA 2LYDA 4HAXB 5DH9B 3ULBA 3OANA 3LJUX 1GC6A 2P0FA 1E5WA 2CODA 3D8DA 1I7AA 2I1KA 3PVUA 1V61A 1BAKA 1FHXA 4TKNA 2D9VA 2RGNB 1LB1A 1TXDA 1MK7B 1NTVA 1WGQA 1RJ2A 1W1DA 4L6EA 1DBHA 4F7HA 4HB0B 3FM8C 5FI1A 4HATB 2IFSA 2BCJA 2EMSA 1EAZA 5D3WA 2W2XC 1ISNA 2V76A 2NZ8B 4DX90 3ZVRA 2D9YA 4K17A 4GZUA 4CHJA 2I1JA 1FGYA 2Q13A 4YL8A 3P6AA 3VOQA 4D0NB 5HE3A 2DLWA 1SGHA 3ODXA 3QWMA 1MIXA 3FEHA 1GG3A 1M7EA 5GOWB 2ELAA 4HB3B 4KHAA 3FSSA 5CLQB 4EMOA 5KCVA 3PVWA 1NI2A 1PMSA 2DN6A 5C5BB 5EFXA 2COAA 4B6HA 3M1IB 2YF0A 4GN1A 1WVHA 4WSFA 2CY5A 1UEFA 1WJMA 5JHGA 4GXBA 2W2XD 5J3TA 2J0MA 3SYXA 2QKMA 2CAYA 5L81A 2LKOA 3WYFB 2HE7A 3HK0A 4A5KA 3PSCA 2DKQA 3A8PA 1W1GA 2RNRB 4HDOA 2DKPA 2LOXA 4Z2NA 2MKRA 4GMXB 3ULCA 3QIJA 2P8VA 2J59M 2L1CA 3AJ4A 2UZRA 4HAZB 2KGXB 1K5GB 1QC6A 4HDQA 3KSYA 2K2UA 1NTYA 4PQ0A 1B55A 4K81A 5JHHA 2Z0QA 1UNRA 4H8SA 1V5MA 3GYPA 1K5DB 2AL6A 2DX1A 3HW2B 5D3XA 1MKEA 4Z2MB 1MIZB 3MPXA 4K2PA 4MT7A 5DHFB 2Y8GA 2D9WA 3PEGA 2G35A 3CIKA 2LOZA 4NSWA 3DXCA 1U29A 3HQCA 2IYBA 2D2QA 2NMBA 2RUKB 2LG1A 5HE0A 4HHVA 3DXDA 2D9ZA 2DYQA 4GPTB 3SNHA 2CRFA 5HE2A 1H10A 3UZTA 2HTHB 4IOYX 2D10A 2Y7BA 5HE1A 3A8QA 3VIAA 4CHMA 4CYEA 3WA0A 2EJ8A 1XD4A 1MAIA 2FJLA 3ML4A 2P0HA 3U7DA 2KUPA 4WVFB 5JLJB 1U27A 5DIFB 2DHIA 1M7RA 1ZM0A 1ZVRA 4ZRJA 2H7DA 5C79A 5J3QA 1Y19B 4KHBB 4ZRIA 2I5FA 1U2BA 5C16A 2YVCA 3TVVA 5C5BA 4BBKA 3F5RA 2QKLA 1X1GA 3X23A 5DHAB 2YT1A 2UVMA 2D11A 1OMWA 2R0DA 4HAYB 1ZSQA 5KQ4A 1DDVA 3PVLA 2K00A 1UNQA 2AEHA 2COCA 3PZDA 2D4QA 4MY6A 3GYOA 3BJIA 4PNKA 1DROA 1U5GA 4IFSA 4EKUA 2ZPYA 1KI1B 2MDXA 1KZ7A 2Z0OA 2ADZA 2I5CA 1UPQA 1GC7A 4A6FB 1FAOA 3ODOA 1WI1A 5D3YA 4IAPA 1EVHA 1FGZA 4TYZA 4WJ7A 4Y94A 3ZDTA 3NSUA 2ROZB 2JP2A 2LULA 1DDMA 2OTXA 2ELBA 2J0KA 3N7CA 2W2WA 3TO1A 3PP2A 1U5DA 4C0AA 3AU4A 2VKIA 5D3VA 2DTCA 4HB2B 4A6KA 3SUZA 2RSGA 3G9WA 2YSZA 3SV1A 4P7IA 4HAUB 2GJYA 2VRWB 1ZC3B 1XR0B 3BINA 1FB8A 1DYNA 1SHCA 1Z87A 2E2XA 1FHWA 2H7EA 1NU2A 1MPHA 1Y5OA 4HAVB 3DXEA 2DX5A 2COFA 2YS3A 5D27A 1TJ6A 3KY9A 1EGXA 1LW3A 2MWNB 2N0YA 2YS1A 1V5UA 2GCLA 5FI0A 2DHKA 2RVBB 4A6HA 3F0WA 3IVFA 3O96A 2M14A 1WG7A 1P6SA 1X86A 1U5FA 1OQNA 3P7ZA 1FHOA 1P5TA 4F7UP 4HAWB 2VSZA 3D8EA 4DX8A 4GMVA 3V5WA 1P3RA 2MFQA 4HB4B 3QBVB 4KAXB 5LOPB 1V88A 2Z0PA 1PFJA 5DI9B 3KZ1A 2GS0A
chains in the Genus database with same CATH superfamily
4KHOA 3KRXA 2PZ1A 3PG7A 1QQGA 1OY2A 2UZSA 2DA0A 4DXAB 3NW8A 1ZC4B 2YRYA 2OQBA 3ODWA 2EC1A 2D9XA 2GCJA 1X11A 3OHMB 1Q67A 2Z13A 3B77A 3KRWA 3T06A 1KZGA 3CXBB 2M38A 2KCJA 3AU5A 5CLLB 2YT0A 3TFMA 2K8EA 4DBBA 1DDWA 2N23A 2K2JA 1W1HA 1WGUA 4A6FA 1X1FA 2RRFA 3D8FA 3TCAA 3U8ZA 1V5PA 1XODA 5C6RA 1XKEA 2XQNM 4KVGB 4CSQA 1BTKA 2GUMA 3MDBC 4K2OA 1BTNA 1BWNA 1J19A 1TQZA 2CY4A 1X05A 5KQ1A 4NY0A 1I2HA 2L2IA 4MK0A 1RRPB 3TW1A 4EJNA 4F7GA 3RCPA 2X18A 1UNPA 4YONA 2DHJA 1U5EA 3FVCA 2J0JA 2DYNA 2P0DA 1AWEA 3SO6A 2ROVA 1EF1A 2Y8FA 1XX0A 2R09A 1IRSA 1XCGA 1N3HA 2EMTA 5I2MA 2RLOA 2DFKA 1MK9B 5J3YA 1PLSA 5JP4A 1UPRA 1V89A 2YS5A 1WJ1A 3A98B 5LONB 1J0WA 1FOEA 4ZRKA 1H4RA 1AQCA 4XWXA 2LYDA 4HAXB 5DH9B 3ULBA 3LJUX 3OANA 1T77A 1GC6A 2P0FA 1E5WA 2CODA 3D8DA 1I7AA 2I1KA 3PVUA 1V61A 1BAKA 1FHXA 4TKNA 2D9VA 2RGNB 1LB1A 1TXDA 1MK7B 1NTVA 1WGQA 1RJ2A 1W1DA 4L6EA 1DBHA 4F7HA 4HB0B 3FM8C 5FI1A 3A58A 4HATB 2IFSA 2BCJA 2EMSA 1EAZA 3NWDA 2W2XC 5D3WA 1ISNA 2V76A 4QJ4B 2NZ8B 4DX90 3ZVRA 4OT1A 2D9YA 4K17A 2K49A 4GZUA 4CHJA 2I1JA 1FGYA 2Q13A 4YL8A 3P6AA 3VOQA 4D0NB 5HE3A 2DLWA 2R2YA 1SGHA 3ODXA 3QWMA 2ZKMX 1MIXA 3FEHA 1GG3A 1M7EA 5GOWB 2ELAA 4HB3B 4KHAA 3FSSA 5CLQB 4EMOA 5KCVA 3PVWA 1NI2A 1PMSA 2DN6A 5C5BB 5EFXA 2KIEA 2COAA 4B6HA 3M1IB 2YF0A 4GN1A 1WVHA 4WSFA 2CY5A 1UEFA 1WJMA 1ZYIA 5JHGA 4GXBA 4OSNA 2W2XD 5J3TA 2J0MA 3SYXA 2QKMA 2CAYA 5L81A 5IRSA 2LKOA 3WYFB 2HE7A 3HK0A 4A5KA 2DKQA 3PSCA 3A8PA 1W1GA 2RNRB 4HDOA 2DKPA 2LOXA 4Z2NA 2MKRA 4GMXB 3ULCA 3QIJA 2P8VA 4HSIA 2J59M 2L1CA 3AJ4A 2UZRA 3NWAA 4HAZB 2KGXB 1K5GB 4QXAB 3HIEA 1QC6A 4HDQA 3KSYA 2K2UA 1NTYA 4PQ0A 1B55A 2Z59A 4K81A 5JHHA 2Z0QA 1UNRA 4H8SA 1V5MA 3GYPA 1K5DB 2AL6A 2DX1A 3HW2B 5D3XA 5I2SA 1MKEA 1MI1A 2FJUB 4Z2MB 1MIZB 3MPXA 4K2PA 4MT7A 5DHFB 2Y8GA 4QJ5B 4GOUA 2D9WA 3PEGA 2G35A 3CIKA 2Z14A 2LOZA 4NSWA 3DXCA 1U29A 3HQCA 2IYBA 2RUKB 2D2QA 2NMBA 2LG1A 5HE0A 4HHVA 3DXDA 2D9ZA 2DYQA 4GPTB 3SNHA 2CRFA 5HE2A 1H10A 3HSAA 3UZTA 2HTHB 4IOYX 2D10A 2Y7BA 5HE1A 3A8QA 3VIAA 4CHMA 4CYEA 3WA0A 2EJ8A 1XD4A 1MAIA 2FJLA 3ML4A 2P0HA 4GNKB 2KUPA 3U7DA 4WVFB 5JLJB 1U27A 5M4YB 5DIFB 2DHIA 1M7RA 1ZM0A 1ZVRA 4ZRJA 2H7DA 5C79A 5J3QA 1Y19B 4KHBB 4ZRIA 2I5FA 1U2BA 5C16A 2YVCA 3TVVA 5C5BA 4BBKA 3F5RA 2QKLA 3NWFA 1X1GA 3X23A 5DHAB 4DIXA 2YT1A 2UVMA 2D11A 1OMWA 2R0DA 4HAYB 1ZSQA 3U12A 5KQ4A 1DDVA 3PVLA 2K00A 1UNQA 2AEHA 2COCA 3PZDA 2D4QA 4MY6A 3GYOA 3BJIA 4PNKA 1DROA 1U5GA 4IFSA 4EKUA 5LG4B 2ZPYA 1KI1B 2MDXA 1KZ7A 2Z0OA 2ADZA 2I5CA 1UPQA 1GC7A 4A6FB 1FAOA 3ODOA 1WI1A 5D3YA 4IAPA 1EVHA 1FGZA 4TYZA 4WJ7A 4Y94A 3ZDTA 3NSUA 2ROZB 2JP2A 2LULA 2NBVA 1DDMA 2OTXA 2ELBA 2J0KA 3N7CA 2W2WA 3TO1A 3PP2A 4L1RA 1U5DA 2YT2A 4C0AA 3AU4A 2VKIA 5D3VA 2DTCA 4HB2B 2KIGA 3SUZA 4A6KA 2RSGA 3G9WA 2YSZA 3SV1A 4QJ3B 4P7IA 4HAUB 2GJYA 2VRWB 1ZC3B 1XR0B 3BINA 1FB8A 1DYNA 1SHCA 1Z87A 2E2XA 1FHWA 2H7EA 1NU2A 1MPHA 1Y5OA 4HAVB 3DXEA 2DX5A 2COFA 2YS3A 5D27A 1TJ6A 3KY9A 1EGXA 2Z4DA 1LW3A 2MWNB 2N0YA 2YS1A 1V5UA 2GCLA 5FI0A 2DHKA 2RVBB 4A6HA 3F0WA 3IVFA 3O96A 2M14A 1WG7A 1P6SA 1X86A 3DCXA 1U5FA 1OQNA 3P7ZA 1FHOA 1P5TA 4F7UP 4HAWB 2VSZA 2KUQA 3D8EA 4DX8A 4GMVA 4KHBA 1P3RA 2MFQA 4HB4B 3QBVB 4KAXB 3V5WA 1V88A 2Z0PA 5LOPB 1PFJA 5DI9B 4D6WA 3KZ1A 2GS0A 2KR0A
chains in the Genus database with same CATH topology
4KHOA 3KRXA 2PZ1A 3PG7A 1QQGA 1OY2A 2UZSA 2DA0A 4DXAB 1ZC4B 2YRYA 2OQBA 3ODWA 2EC1A 2D9XA 2GCJA 1X11A 1Q67A 3KRWA 3T06A 1KZGA 3CXBB 2M38A 2KCJA 3AU5A 5CLLB 2YT0A 3TFMA 4DBBA 1DDWA 2N23A 2K2JA 1W1HA 1WGUA 4A6FA 1X1FA 3D8FA 3TCAA 3U8ZA 1V5PA 1XODA 5C6RA 1XKEA 2XQNM 4KVGB 1BTKA 3MDBC 4K2OA 1BTNA 1BWNA 1J19A 1TQZA 2CY4A 1X05A 5KQ1A 4NY0A 1I2HA 2L2IA 4MK0A 1RRPB 3TW1A 4EJNA 4F7GA 3RCPA 2X18A 1UNPA 4YONA 2DHJA 1U5EA 2J0JA 2DYNA 2P0DA 1AWEA 3SO6A 2ROVA 1EF1A 2Y8FA 1XX0A 2R09A 1IRSA 1XCGA 1N3HA 2EMTA 2RLOA 2DFKA 1MK9B 5J3YA 1PLSA 5JP4A 1UPRA 1V89A 2YS5A 1WJ1A 3A98B 5LONB 1J0WA 1FOEA 4ZRKA 1H4RA 1AQCA 4XWXA 2LYDA 4HAXB 5DH9B 3ULBA 3OANA 3LJUX 1GC6A 2P0FA 1E5WA 2CODA 3D8DA 1I7AA 2I1KA 3PVUA 1V61A 1BAKA 1FHXA 4TKNA 2D9VA 2RGNB 1LB1A 1TXDA 1MK7B 1NTVA 1WGQA 1RJ2A 1W1DA 4L6EA 1DBHA 4F7HA 4HB0B 3FM8C 5FI1A 4HATB 2IFSA 2BCJA 2EMSA 1EAZA 5D3WA 2W2XC 1ISNA 2V76A 2NZ8B 4DX90 3ZVRA 2D9YA 4K17A 4GZUA 4CHJA 2I1JA 1FGYA 2Q13A 4YL8A 3P6AA 3VOQA 4D0NB 5HE3A 2DLWA 1SGHA 3ODXA 3QWMA 1MIXA 3FEHA 1GG3A 1M7EA 5GOWB 2ELAA 4HB3B 4KHAA 3FSSA 5CLQB 4EMOA 5KCVA 3PVWA 1NI2A 1PMSA 2DN6A 5C5BB 5EFXA 2COAA 4B6HA 3M1IB 2YF0A 4GN1A 1WVHA 4WSFA 2CY5A 1UEFA 1WJMA 5JHGA 4GXBA 2W2XD 5J3TA 2J0MA 3SYXA 2QKMA 2CAYA 5L81A 2LKOA 3WYFB 2HE7A 3HK0A 4A5KA 3PSCA 2DKQA 3A8PA 1W1GA 2RNRB 4HDOA 2DKPA 2LOXA 4Z2NA 2MKRA 4GMXB 3ULCA 3QIJA 2P8VA 2J59M 2L1CA 3AJ4A 2UZRA 4HAZB 2KGXB 1K5GB 1QC6A 4HDQA 3KSYA 2K2UA 1NTYA 4PQ0A 1B55A 4K81A 5JHHA 2Z0QA 1UNRA 4H8SA 1V5MA 3GYPA 1K5DB 2AL6A 2DX1A 3HW2B 5D3XA 1MKEA 4Z2MB 1MIZB 3MPXA 4K2PA 4MT7A 5DHFB 2Y8GA 2D9WA 3PEGA 2G35A 3CIKA 2LOZA 4NSWA 3DXCA 1U29A 3HQCA 2IYBA 2D2QA 2NMBA 2RUKB 2LG1A 5HE0A 4HHVA 3DXDA 2D9ZA 2DYQA 4GPTB 3SNHA 2CRFA 5HE2A 1H10A 3UZTA 2HTHB 4IOYX 2D10A 2Y7BA 5HE1A 3A8QA 3VIAA 4CHMA 4CYEA 3WA0A 2EJ8A 1XD4A 1MAIA 2FJLA 3ML4A 2P0HA 3U7DA 2KUPA 4WVFB 5JLJB 1U27A 5DIFB 2DHIA 1M7RA 1ZM0A 1ZVRA 4ZRJA 2H7DA 5C79A 5J3QA 1Y19B 4KHBB 4ZRIA 2I5FA 1U2BA 5C16A 2YVCA 3TVVA 5C5BA 4BBKA 3F5RA 2QKLA 1X1GA 3X23A 5DHAB 2YT1A 2UVMA 2D11A 1OMWA 2R0DA 4HAYB 1ZSQA 5KQ4A 1DDVA 3PVLA 2K00A 1UNQA 2AEHA 2COCA 3PZDA 2D4QA 4MY6A 3GYOA 3BJIA 4PNKA 1DROA 1U5GA 4IFSA 4EKUA 2ZPYA 1KI1B 2MDXA 1KZ7A 2Z0OA 2ADZA 2I5CA 1UPQA 1GC7A 4A6FB 1FAOA 3ODOA 1WI1A 5D3YA 4IAPA 1EVHA 1FGZA 4TYZA 4WJ7A 4Y94A 3ZDTA 3NSUA 2ROZB 2JP2A 2LULA 1DDMA 2OTXA 2ELBA 2J0KA 3N7CA 2W2WA 3TO1A 3PP2A 1U5DA 4C0AA 3AU4A 2VKIA 5D3VA 2DTCA 4HB2B 4A6KA 3SUZA 2RSGA 3G9WA 2YSZA 3SV1A 4P7IA 4HAUB 2GJYA 2VRWB 1ZC3B 1XR0B 3BINA 1FB8A 1DYNA 1SHCA 1Z87A 2E2XA 1FHWA 2H7EA 1NU2A 1MPHA 1Y5OA 4HAVB 3DXEA 2DX5A 2COFA 2YS3A 5D27A 1TJ6A 3KY9A 1EGXA 1LW3A 2MWNB 2N0YA 2YS1A 1V5UA 2GCLA 5FI0A 2DHKA 2RVBB 4A6HA 3F0WA 3IVFA 3O96A 2M14A 1WG7A 1P6SA 1X86A 1U5FA 1OQNA 3P7ZA 1FHOA 1P5TA 4F7UP 4HAWB 2VSZA 3D8EA 4DX8A 4GMVA 3V5WA 1P3RA 2MFQA 4HB4B 3QBVB 4KAXB 5LOPB 1V88A 2Z0PA 1PFJA 5DI9B 3KZ1A 2GS0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KHO A;  3KRX A;  2PZ1 A;  3PG7 A;  1QQG A;  1OY2 A;  2UZS A;  2DA0 A;  4DXA B;  1ZC4 B;  2YRY A;  2OQB A;  3ODW A;  2EC1 A;  2D9X A;  2GCJ A;  1X11 A;  1Q67 A;  3KRW A;  3T06 A;  1KZG A;  3CXB B;  2M38 A;  2KCJ A;  3AU5 A;  5CLL B;  2YT0 A;  3TFM A;  4DBB A;  1DDW A;  2N23 A;  2K2J A;  1W1H A;  1WGU A;  4A6F A;  1X1F A;  3D8F A;  3TCA A;  3U8Z A;  1V5P A;  1XOD A;  5C6R A;  1XKE A;  2XQN M;  4KVG B;  1BTK A;  3MDB C;  4K2O A;  1BTN A;  1BWN A;  1J19 A;  1TQZ A;  2CY4 A;  1X05 A;  5KQ1 A;  4NY0 A;  1I2H A;  2L2I A;  4MK0 A;  1RRP B;  3TW1 A;  4EJN A;  4F7G A;  3RCP A;  2X18 A;  1UNP A;  4YON A;  2DHJ A;  1U5E A;  2J0J A;  2DYN A;  2P0D A;  1AWE A;  3SO6 A;  2ROV A;  1EF1 A;  2Y8F A;  1XX0 A;  2R09 A;  1IRS A;  1XCG A;  1N3H A;  2EMT A;  2RLO A;  2DFK A;  1MK9 B;  5J3Y A;  1PLS A;  5JP4 A;  1UPR A;  1V89 A;  2YS5 A;  1WJ1 A;  3A98 B;  5LON B;  1J0W A;  1FOE A;  4ZRK A;  1H4R A;  1AQC A;  4XWX A;  2LYD A;  4HAX B;  5DH9 B;  3ULB A;  3OAN A;  3LJU X;  1GC6 A;  2P0F A;  1E5W A;  2COD A;  3D8D A;  1I7A A;  2I1K A;  3PVU A;  1V61 A;  1BAK A;  1FHX A;  4TKN A;  2D9V A;  2RGN B;  1LB1 A;  1TXD A;  1MK7 B;  1NTV A;  1WGQ A;  1RJ2 A;  1W1D A;  4L6E A;  1DBH A;  4F7H A;  4HB0 B;  3FM8 C;  5FI1 A;  4HAT B;  2IFS A;  2BCJ A;  2EMS A;  1EAZ A;  5D3W A;  2W2X C;  1ISN A;  2V76 A;  2NZ8 B;  4DX9 0;  3ZVR A;  2D9Y A;  4K17 A;  4GZU A;  4CHJ A;  2I1J A;  1FGY A;  2Q13 A;  4YL8 A;  3P6A A;  3VOQ A;  4D0N B;  5HE3 A;  2DLW A;  1SGH A;  3ODX A;  3QWM A;  1MIX A;  3FEH A;  1GG3 A;  1M7E A;  5GOW B;  2ELA A;  4HB3 B;  4KHA A;  3FSS A;  5CLQ B;  4EMO A;  5KCV A;  3PVW A;  1NI2 A;  1PMS A;  2DN6 A;  5C5B B;  5EFX A;  2COA A;  4B6H A;  3M1I B;  2YF0 A;  4GN1 A;  1WVH A;  4WSF A;  2CY5 A;  1UEF A;  1WJM A;  5JHG A;  4GXB A;  2W2X D;  5J3T A;  2J0M A;  3SYX A;  2QKM A;  2CAY A;  5L81 A;  2LKO A;  3WYF B;  2HE7 A;  3HK0 A;  4A5K A;  3PSC A;  2DKQ A;  3A8P A;  1W1G A;  2RNR B;  4HDO A;  2DKP A;  2LOX A;  4Z2N A;  2MKR A;  4GMX B;  3ULC A;  3QIJ A;  2P8V A;  2J59 M;  2L1C A;  3AJ4 A;  2UZR A;  4HAZ B;  2KGX B;  1K5G B;  1QC6 A;  4HDQ A;  3KSY A;  2K2U A;  1NTY A;  4PQ0 A;  1B55 A;  4K81 A;  5JHH A;  2Z0Q A;  1UNR A;  4H8S A;  1V5M A;  3GYP A;  1K5D B;  2AL6 A;  2DX1 A;  3HW2 B;  5D3X A;  1MKE A;  4Z2M B;  1MIZ B;  3MPX A;  4K2P A;  4MT7 A;  5DHF B;  2Y8G A;  2D9W A;  3PEG A;  2G35 A;  3CIK A;  2LOZ A;  4NSW A;  3DXC A;  1U29 A;  3HQC A;  2IYB A;  2D2Q A;  2NMB A;  2RUK B;  2LG1 A;  5HE0 A;  4HHV A;  3DXD A;  2D9Z A;  2DYQ A;  4GPT B;  3SNH A;  2CRF A;  5HE2 A;  1H10 A;  3UZT A;  2HTH B;  4IOY X;  2D10 A;  2Y7B A;  5HE1 A;  3A8Q A;  3VIA A;  4CHM A;  4CYE A;  3WA0 A;  2EJ8 A;  1XD4 A;  1MAI A;  2FJL A;  3ML4 A;  2P0H A;  3U7D A;  2KUP A;  4WVF B;  5JLJ B;  1U27 A;  5DIF B;  2DHI A;  1M7R A;  1ZM0 A;  1ZVR A;  4ZRJ A;  2H7D A;  5C79 A;  5J3Q A;  1Y19 B;  4KHB B;  4ZRI A;  2I5F A;  1U2B A;  5C16 A;  2YVC A;  3TVV A;  5C5B A;  4BBK A;  3F5R A;  2QKL A;  1X1G A;  3X23 A;  5DHA B;  2YT1 A;  2UVM A;  2D11 A;  1OMW A;  2R0D A;  4HAY B;  1ZSQ A;  5KQ4 A;  1DDV A;  3PVL A;  2K00 A;  1UNQ A;  2AEH A;  2COC A;  3PZD A;  2D4Q A;  4MY6 A;  3GYO A;  3BJI A;  4PNK A;  1DRO A;  1U5G A;  4IFS A;  4EKU A;  2ZPY A;  1KI1 B;  2MDX A;  1KZ7 A;  2Z0O A;  2ADZ A;  2I5C A;  1UPQ A;  1GC7 A;  4A6F B;  1FAO A;  3ODO A;  1WI1 A;  5D3Y A;  4IAP A;  1EVH A;  1FGZ A;  4TYZ A;  4WJ7 A;  4Y94 A;  3ZDT A;  3NSU A;  2ROZ B;  2JP2 A;  2LUL A;  1DDM A;  2OTX A;  2ELB A;  2J0K A;  3N7C A;  2W2W A;  3TO1 A;  3PP2 A;  1U5D A;  4C0A A;  3AU4 A;  2VKI A;  5D3V A;  2DTC A;  4HB2 B;  4A6K A;  3SUZ A;  2RSG A;  3G9W A;  2YSZ A;  3SV1 A;  4P7I A;  4HAU B;  2GJY A;  2VRW B;  1ZC3 B;  1XR0 B;  3BIN A;  1FB8 A;  1DYN A;  1SHC A;  1Z87 A;  2E2X A;  1FHW A;  2H7E A;  1NU2 A;  1MPH A;  1Y5O A;  4HAV B;  3DXE A;  2DX5 A;  2COF A;  2YS3 A;  5D27 A;  1TJ6 A;  3KY9 A;  1EGX A;  1LW3 A;  2MWN B;  2N0Y A;  2YS1 A;  1V5U A;  2GCL A;  5FI0 A;  2DHK A;  2RVB B;  4A6H A;  3F0W A;  3IVF A;  3O96 A;  2M14 A;  1WG7 A;  1P6S A;  1X86 A;  1U5F A;  1OQN A;  3P7Z A;  1FHO A;  1P5T A;  4F7U P;  4HAW B;  2VSZ A;  3D8E A;  4DX8 A;  4GMV A;  3V5W A;  1P3R A;  2MFQ A;  4HB4 B;  3QBV B;  4KAX B;  5LOP B;  1V88 A;  2Z0P A;  1PFJ A;  5DI9 B;  3KZ1 A;  2GS0 A; 
#chains in the Genus database with same CATH topology
 4KHO A;  3KRX A;  2PZ1 A;  3PG7 A;  1QQG A;  1OY2 A;  2UZS A;  2DA0 A;  4DXA B;  3NW8 A;  1ZC4 B;  2YRY A;  2OQB A;  3ODW A;  2EC1 A;  2D9X A;  2GCJ A;  1X11 A;  3OHM B;  1Q67 A;  2Z13 A;  3B77 A;  3KRW A;  3T06 A;  1KZG A;  3CXB B;  2M38 A;  2KCJ A;  3AU5 A;  5CLL B;  2YT0 A;  3TFM A;  2K8E A;  4DBB A;  1DDW A;  2N23 A;  2K2J A;  1W1H A;  1WGU A;  4A6F A;  1X1F A;  2RRF A;  3D8F A;  3TCA A;  3U8Z A;  1V5P A;  1XOD A;  5C6R A;  1XKE A;  2XQN M;  4KVG B;  4CSQ A;  1BTK A;  2GUM A;  3MDB C;  4K2O A;  1BTN A;  1BWN A;  1J19 A;  1TQZ A;  2CY4 A;  1X05 A;  5KQ1 A;  4NY0 A;  1I2H A;  2L2I A;  4MK0 A;  1RRP B;  3TW1 A;  4EJN A;  4F7G A;  3RCP A;  2X18 A;  1UNP A;  4YON A;  2DHJ A;  1U5E A;  3FVC A;  2J0J A;  2DYN A;  2P0D A;  1AWE A;  3SO6 A;  2ROV A;  1EF1 A;  2Y8F A;  1XX0 A;  2R09 A;  1IRS A;  1XCG A;  1N3H A;  2EMT A;  5I2M A;  2RLO A;  2DFK A;  1MK9 B;  5J3Y A;  1PLS A;  5JP4 A;  1UPR A;  1V89 A;  2YS5 A;  1WJ1 A;  3A98 B;  5LON B;  1J0W A;  1FOE A;  4ZRK A;  1H4R A;  1AQC A;  4XWX A;  2LYD A;  4HAX B;  5DH9 B;  3ULB A;  3LJU X;  3OAN A;  1T77 A;  1GC6 A;  2P0F A;  1E5W A;  2COD A;  3D8D A;  1I7A A;  2I1K A;  3PVU A;  1V61 A;  1BAK A;  1FHX A;  4TKN A;  2D9V A;  2RGN B;  1LB1 A;  1TXD A;  1MK7 B;  1NTV A;  1WGQ A;  1RJ2 A;  1W1D A;  4L6E A;  1DBH A;  4F7H A;  4HB0 B;  3FM8 C;  5FI1 A;  3A58 A;  4HAT B;  2IFS A;  2BCJ A;  2EMS A;  1EAZ A;  3NWD A;  2W2X C;  5D3W A;  1ISN A;  2V76 A;  4QJ4 B;  2NZ8 B;  4DX9 0;  3ZVR A;  4OT1 A;  2D9Y A;  4K17 A;  2K49 A;  4GZU A;  4CHJ A;  2I1J A;  1FGY A;  2Q13 A;  4YL8 A;  3P6A A;  3VOQ A;  4D0N B;  5HE3 A;  2DLW A;  2R2Y A;  1SGH A;  3ODX A;  3QWM A;  2ZKM X;  1MIX A;  3FEH A;  1GG3 A;  1M7E A;  5GOW B;  2ELA A;  4HB3 B;  4KHA A;  3FSS A;  5CLQ B;  4EMO A;  5KCV A;  3PVW A;  1NI2 A;  1PMS A;  2DN6 A;  5C5B B;  5EFX A;  2KIE A;  2COA A;  4B6H A;  3M1I B;  2YF0 A;  4GN1 A;  1WVH A;  4WSF A;  2CY5 A;  1UEF A;  1WJM A;  1ZYI A;  5JHG A;  4GXB A;  4OSN A;  2W2X D;  5J3T A;  2J0M A;  3SYX A;  2QKM A;  2CAY A;  5L81 A;  5IRS A;  2LKO A;  3WYF B;  2HE7 A;  3HK0 A;  4A5K A;  2DKQ A;  3PSC A;  3A8P A;  1W1G A;  2RNR B;  4HDO A;  2DKP A;  2LOX A;  4Z2N A;  2MKR A;  4GMX B;  3ULC A;  3QIJ A;  2P8V A;  4HSI A;  2J59 M;  2L1C A;  3AJ4 A;  2UZR A;  3NWA A;  4HAZ B;  2KGX B;  1K5G B;  4QXA B;  3HIE A;  1QC6 A;  4HDQ A;  3KSY A;  2K2U A;  1NTY A;  4PQ0 A;  1B55 A;  2Z59 A;  4K81 A;  5JHH A;  2Z0Q A;  1UNR A;  4H8S A;  1V5M A;  3GYP A;  1K5D B;  2AL6 A;  2DX1 A;  3HW2 B;  5D3X A;  5I2S A;  1MKE A;  1MI1 A;  2FJU B;  4Z2M B;  1MIZ B;  3MPX A;  4K2P A;  4MT7 A;  5DHF B;  2Y8G A;  4QJ5 B;  4GOU A;  2D9W A;  3PEG A;  2G35 A;  3CIK A;  2Z14 A;  2LOZ A;  4NSW A;  3DXC A;  1U29 A;  3HQC A;  2IYB A;  2RUK B;  2D2Q A;  2NMB A;  2LG1 A;  5HE0 A;  4HHV A;  3DXD A;  2D9Z A;  2DYQ A;  4GPT B;  3SNH A;  2CRF A;  5HE2 A;  1H10 A;  3HSA A;  3UZT A;  2HTH B;  4IOY X;  2D10 A;  2Y7B A;  5HE1 A;  3A8Q A;  3VIA A;  4CHM A;  4CYE A;  3WA0 A;  2EJ8 A;  1XD4 A;  1MAI A;  2FJL A;  3ML4 A;  2P0H A;  4GNK B;  2KUP A;  3U7D A;  4WVF B;  5JLJ B;  1U27 A;  5M4Y B;  5DIF B;  2DHI A;  1M7R A;  1ZM0 A;  1ZVR A;  4ZRJ A;  2H7D A;  5C79 A;  5J3Q A;  1Y19 B;  4KHB B;  4ZRI A;  2I5F A;  1U2B A;  5C16 A;  2YVC A;  3TVV A;  5C5B A;  4BBK A;  3F5R A;  2QKL A;  3NWF A;  1X1G A;  3X23 A;  5DHA B;  4DIX A;  2YT1 A;  2UVM A;  2D11 A;  1OMW A;  2R0D A;  4HAY B;  1ZSQ A;  3U12 A;  5KQ4 A;  1DDV A;  3PVL A;  2K00 A;  1UNQ A;  2AEH A;  2COC A;  3PZD A;  2D4Q A;  4MY6 A;  3GYO A;  3BJI A;  4PNK A;  1DRO A;  1U5G A;  4IFS A;  4EKU A;  5LG4 B;  2ZPY A;  1KI1 B;  2MDX A;  1KZ7 A;  2Z0O A;  2ADZ A;  2I5C A;  1UPQ A;  1GC7 A;  4A6F B;  1FAO A;  3ODO A;  1WI1 A;  5D3Y A;  4IAP A;  1EVH A;  1FGZ A;  4TYZ A;  4WJ7 A;  4Y94 A;  3ZDT A;  3NSU A;  2ROZ B;  2JP2 A;  2LUL A;  2NBV A;  1DDM A;  2OTX A;  2ELB A;  2J0K A;  3N7C A;  2W2W A;  3TO1 A;  3PP2 A;  4L1R A;  1U5D A;  2YT2 A;  4C0A A;  3AU4 A;  2VKI A;  5D3V A;  2DTC A;  4HB2 B;  2KIG A;  3SUZ A;  4A6K A;  2RSG A;  3G9W A;  2YSZ A;  3SV1 A;  4QJ3 B;  4P7I A;  4HAU B;  2GJY A;  2VRW B;  1ZC3 B;  1XR0 B;  3BIN A;  1FB8 A;  1DYN A;  1SHC A;  1Z87 A;  2E2X A;  1FHW A;  2H7E A;  1NU2 A;  1MPH A;  1Y5O A;  4HAV B;  3DXE A;  2DX5 A;  2COF A;  2YS3 A;  5D27 A;  1TJ6 A;  3KY9 A;  1EGX A;  2Z4D A;  1LW3 A;  2MWN B;  2N0Y A;  2YS1 A;  1V5U A;  2GCL A;  5FI0 A;  2DHK A;  2RVB B;  4A6H A;  3F0W A;  3IVF A;  3O96 A;  2M14 A;  1WG7 A;  1P6S A;  1X86 A;  3DCX A;  1U5F A;  1OQN A;  3P7Z A;  1FHO A;  1P5T A;  4F7U P;  4HAW B;  2VSZ A;  2KUQ A;  3D8E A;  4DX8 A;  4GMV A;  4KHB A;  1P3R A;  2MFQ A;  4HB4 B;  3QBV B;  4KAX B;  3V5W A;  1V88 A;  2Z0P A;  5LOP B;  1PFJ A;  5DI9 B;  4D6W A;  3KZ1 A;  2GS0 A;  2KR0 A; 
#chains in the Genus database with same CATH homology
 4KHO A;  3KRX A;  2PZ1 A;  3PG7 A;  1QQG A;  1OY2 A;  2UZS A;  2DA0 A;  4DXA B;  1ZC4 B;  2YRY A;  2OQB A;  3ODW A;  2EC1 A;  2D9X A;  2GCJ A;  1X11 A;  1Q67 A;  3KRW A;  3T06 A;  1KZG A;  3CXB B;  2M38 A;  2KCJ A;  3AU5 A;  5CLL B;  2YT0 A;  3TFM A;  4DBB A;  1DDW A;  2N23 A;  2K2J A;  1W1H A;  1WGU A;  4A6F A;  1X1F A;  3D8F A;  3TCA A;  3U8Z A;  1V5P A;  1XOD A;  5C6R A;  1XKE A;  2XQN M;  4KVG B;  1BTK A;  3MDB C;  4K2O A;  1BTN A;  1BWN A;  1J19 A;  1TQZ A;  2CY4 A;  1X05 A;  5KQ1 A;  4NY0 A;  1I2H A;  2L2I A;  4MK0 A;  1RRP B;  3TW1 A;  4EJN A;  4F7G A;  3RCP A;  2X18 A;  1UNP A;  4YON A;  2DHJ A;  1U5E A;  2J0J A;  2DYN A;  2P0D A;  1AWE A;  3SO6 A;  2ROV A;  1EF1 A;  2Y8F A;  1XX0 A;  2R09 A;  1IRS A;  1XCG A;  1N3H A;  2EMT A;  2RLO A;  2DFK A;  1MK9 B;  5J3Y A;  1PLS A;  5JP4 A;  1UPR A;  1V89 A;  2YS5 A;  1WJ1 A;  3A98 B;  5LON B;  1J0W A;  1FOE A;  4ZRK A;  1H4R A;  1AQC A;  4XWX A;  2LYD A;  4HAX B;  5DH9 B;  3ULB A;  3OAN A;  3LJU X;  1GC6 A;  2P0F A;  1E5W A;  2COD A;  3D8D A;  1I7A A;  2I1K A;  3PVU A;  1V61 A;  1BAK A;  1FHX A;  4TKN A;  2D9V A;  2RGN B;  1LB1 A;  1TXD A;  1MK7 B;  1NTV A;  1WGQ A;  1RJ2 A;  1W1D A;  4L6E A;  1DBH A;  4F7H A;  4HB0 B;  3FM8 C;  5FI1 A;  4HAT B;  2IFS A;  2BCJ A;  2EMS A;  1EAZ A;  5D3W A;  2W2X C;  1ISN A;  2V76 A;  2NZ8 B;  4DX9 0;  3ZVR A;  2D9Y A;  4K17 A;  4GZU A;  4CHJ A;  2I1J A;  1FGY A;  2Q13 A;  4YL8 A;  3P6A A;  3VOQ A;  4D0N B;  5HE3 A;  2DLW A;  1SGH A;  3ODX A;  3QWM A;  1MIX A;  3FEH A;  1GG3 A;  1M7E A;  5GOW B;  2ELA A;  4HB3 B;  4KHA A;  3FSS A;  5CLQ B;  4EMO A;  5KCV A;  3PVW A;  1NI2 A;  1PMS A;  2DN6 A;  5C5B B;  5EFX A;  2COA A;  4B6H A;  3M1I B;  2YF0 A;  4GN1 A;  1WVH A;  4WSF A;  2CY5 A;  1UEF A;  1WJM A;  5JHG A;  4GXB A;  2W2X D;  5J3T A;  2J0M A;  3SYX A;  2QKM A;  2CAY A;  5L81 A;  2LKO A;  3WYF B;  2HE7 A;  3HK0 A;  4A5K A;  3PSC A;  2DKQ A;  3A8P A;  1W1G A;  2RNR B;  4HDO A;  2DKP A;  2LOX A;  4Z2N A;  2MKR A;  4GMX B;  3ULC A;  3QIJ A;  2P8V A;  2J59 M;  2L1C A;  3AJ4 A;  2UZR A;  4HAZ B;  2KGX B;  1K5G B;  1QC6 A;  4HDQ A;  3KSY A;  2K2U A;  1NTY A;  4PQ0 A;  1B55 A;  4K81 A;  5JHH A;  2Z0Q A;  1UNR A;  4H8S A;  1V5M A;  3GYP A;  1K5D B;  2AL6 A;  2DX1 A;  3HW2 B;  5D3X A;  1MKE A;  4Z2M B;  1MIZ B;  3MPX A;  4K2P A;  4MT7 A;  5DHF B;  2Y8G A;  2D9W A;  3PEG A;  2G35 A;  3CIK A;  2LOZ A;  4NSW A;  3DXC A;  1U29 A;  3HQC A;  2IYB A;  2D2Q A;  2NMB A;  2RUK B;  2LG1 A;  5HE0 A;  4HHV A;  3DXD A;  2D9Z A;  2DYQ A;  4GPT B;  3SNH A;  2CRF A;  5HE2 A;  1H10 A;  3UZT A;  2HTH B;  4IOY X;  2D10 A;  2Y7B A;  5HE1 A;  3A8Q A;  3VIA A;  4CHM A;  4CYE A;  3WA0 A;  2EJ8 A;  1XD4 A;  1MAI A;  2FJL A;  3ML4 A;  2P0H A;  3U7D A;  2KUP A;  4WVF B;  5JLJ B;  1U27 A;  5DIF B;  2DHI A;  1M7R A;  1ZM0 A;  1ZVR A;  4ZRJ A;  2H7D A;  5C79 A;  5J3Q A;  1Y19 B;  4KHB B;  4ZRI A;  2I5F A;  1U2B A;  5C16 A;  2YVC A;  3TVV A;  5C5B A;  4BBK A;  3F5R A;  2QKL A;  1X1G A;  3X23 A;  5DHA B;  2YT1 A;  2UVM A;  2D11 A;  1OMW A;  2R0D A;  4HAY B;  1ZSQ A;  5KQ4 A;  1DDV A;  3PVL A;  2K00 A;  1UNQ A;  2AEH A;  2COC A;  3PZD A;  2D4Q A;  4MY6 A;  3GYO A;  3BJI A;  4PNK A;  1DRO A;  1U5G A;  4IFS A;  4EKU A;  2ZPY A;  1KI1 B;  2MDX A;  1KZ7 A;  2Z0O A;  2ADZ A;  2I5C A;  1UPQ A;  1GC7 A;  4A6F B;  1FAO A;  3ODO A;  1WI1 A;  5D3Y A;  4IAP A;  1EVH A;  1FGZ A;  4TYZ A;  4WJ7 A;  4Y94 A;  3ZDT A;  3NSU A;  2ROZ B;  2JP2 A;  2LUL A;  1DDM A;  2OTX A;  2ELB A;  2J0K A;  3N7C A;  2W2W A;  3TO1 A;  3PP2 A;  1U5D A;  4C0A A;  3AU4 A;  2VKI A;  5D3V A;  2DTC A;  4HB2 B;  4A6K A;  3SUZ A;  2RSG A;  3G9W A;  2YSZ A;  3SV1 A;  4P7I A;  4HAU B;  2GJY A;  2VRW B;  1ZC3 B;  1XR0 B;  3BIN A;  1FB8 A;  1DYN A;  1SHC A;  1Z87 A;  2E2X A;  1FHW A;  2H7E A;  1NU2 A;  1MPH A;  1Y5O A;  4HAV B;  3DXE A;  2DX5 A;  2COF A;  2YS3 A;  5D27 A;  1TJ6 A;  3KY9 A;  1EGX A;  1LW3 A;  2MWN B;  2N0Y A;  2YS1 A;  1V5U A;  2GCL A;  5FI0 A;  2DHK A;  2RVB B;  4A6H A;  3F0W A;  3IVF A;  3O96 A;  2M14 A;  1WG7 A;  1P6S A;  1X86 A;  1U5F A;  1OQN A;  3P7Z A;  1FHO A;  1P5T A;  4F7U P;  4HAW B;  2VSZ A;  3D8E A;  4DX8 A;  4GMV A;  3V5W A;  1P3R A;  2MFQ A;  4HB4 B;  3QBV B;  4KAX B;  5LOP B;  1V88 A;  2Z0P A;  1PFJ A;  5DI9 B;  3KZ1 A;  2GS0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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