5IRSA

Crystal structure of the proteasomal rpn13 pru-domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
110
structure length
110
Chain Sequence
KYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNEYLNN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Proteasomal ubiquitin receptor ADRM1
total genus 29
structure length 110
sequence length 110
ec nomenclature
pdb deposition date 2016-03-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04683 Proteasom_Rpn13 Proteasome complex subunit Rpn13 ubiquitin receptor
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.70 Mainly Beta Roll PH-domain like PH-domain like 5irsA00
5IRSA 2KR0A 2Z59A 2Z4DA 2R2YA 2NBVA
chains in the Genus database with same CATH superfamily
1P5TA 3OHMB 4K81A 4TYZA 5HE3A 4DX8A 1U5GA 2EC1A 1KZ7A 2COAA 4HSIA 1DYNA 5M4YB 1ZYIA 2CY4A 3NW8A 1WI1A 3U8ZA 3F0WA 5LONB 1MPHA 1DDWA 2GCJA 2D9VA 2Y7BA 3SUZA 1WG7A 2COFA 2P0DA 2IFSA 2D9ZA 3TFMA 5KQ1A 5LG4B 4HAWB 5CLQB 2D2QA 1MIXA 1PFJA 3AU4A 4D0NB 5L81A 4IOYX 1X05A 2VRWB 3ODWA 1ZVRA 4IFSA 4GN1A 2Z0QA 1QC6A 4K2PA 2YS5A 3ULBA 4F7HA 1GG3A 3M1IB 4QJ5B 3DXDA 5D27A 3F5RA 1RRPB 2H7DA 3A8QA 3KY9A 3PVUA 1UNPA 4HDOA 4HB0B 5DIFB 3P7ZA 2I1JA 1DDMA 1J19A 2ROZB 3PVWA 1E5WA 4OT1A 5C5BA 1FB8A 3HW2B 3NSUA 1UPRA 1WJ1A 4HAXB 4ZRIA 4K17A 2NBVA 3FM8C 4KHBA 1LB1A 2DA0A 4PNKA 2L1CA 2LOZA 2KUQA 1X1GA 1V5MA 1SGHA 2D9WA 1TJ6A 2J0MA 4WJ7A 4D6WA 1AQCA 3P6AA 4C0AA 3AU5A 3PSCA 2Z0OA 2V76A 1H10A 5DH9B 2Z59A 5DHAB 1B55A 2YS1A 4A5KA 3O96A 3UZTA 1WJMA 3HQCA 3A8PA 4KAXB 4HB4B 4CYEA 2AL6A 2OQBA 2RVBB 1K5GB 5C5BB 2KIEA 1X86A 1ZC3B 2DX5A 2K49A 4H8SA 2ADZA 3VOQA 3TO1A 5J3TA 2ZPYA 3TVVA 1EF1A 2DLWA 1Q67A 4NSWA 3NWAA 3PZDA 1FHWA 1FHOA 4EKUA 4KHBB 1TQZA 1I2HA 4GOUA 2UZSA 3B77A 2RNRB 2RSGA 5CLLB 1MAIA 1FAOA 1SHCA 4HB3B 1V61A 2PZ1A 1W1GA 2EMSA 4GPTB 4CHMA 2MDXA 3ML4A 4HDQA 4L6EA 1UNQA 2DKQA 4KHOA 4HAYB 1UEFA 2Z0PA 1NI2A 4DX90 1NU2A 1EGXA 2Z13A 4HATB 3WA0A 1KZGA 1P6SA 2D10A 4TKNA 3DXCA 2R2YA 5D3WA 4KVGB 1MI1A 1W1HA 2LKOA 5EFXA 4MY6A 1BWNA 3T06A 5FI1A 4NY0A 1TXDA 4ZRKA 1FGYA 1WGQA 2GCLA 1LW3A 3HSAA 1N3HA 1U27A 2RUKB 4DBBA 2DHIA 4MK0A 5J3QA 2J0KA 2FJUB 2N0YA 3U7DA 1BTKA 1XX0A 2VKIA 2GS0A 3ULCA 4Z2MB 2DYQA 2HTHB 2R0DA 5D3XA 2BCJA 4EMOA 3GYOA 1OY2A 3QBVB 2MKRA 1AWEA 2KCJA 4HAVB 4HB2B 2I1KA 4GMVA 1EAZA 5HE0A 1V5PA 1FGZA 1BTNA 3KSYA 2J59M 1XODA 2RLOA 3TCAA 5J3YA 4IAPA 1NTYA 2D9YA 3TW1A 2EJ8A 2RGNB 2DTCA 2YRYA 3PEGA 5I2SA 3IVFA 4GMXB 3DCXA 4HHVA 2KIGA 2MFQA 4GNKB 2CAYA 4F7GA 1OMWA 5JHGA 1X11A 4P7IA 2I5CA 2DX1A 4QXAB 4BBKA 2ELAA 2LG1A 2Z14A 3D8DA 3PP2A 2NZ8B 3NWDA 1ZM0A 4GZUA 1Y5OA 2CY5A 2RRFA 1RJ2A 2L2IA 3ODXA 4OSNA 4DIXA 2FJLA 1U29A 3CXBB 1DROA 2LYDA 5GOWB 1V89A 3FSSA 1M7RA 4CSQA 3KRWA 1FHXA 2YT0A 2MWNB 2NMBA 2VSZA 1ISNA 2YT2A 3FVCA 2YF0A 2GUMA 2M14A 3ZDTA 3HK0A 1XD4A 2DHJA 3ZVRA 4QJ4B 3GYPA 2CRFA 2P0FA 3A98B 2R09A 4F7UP 4QJ3B 1W1DA 2UZRA 2Y8FA 3U12A 5KQ4A 2DN6A 2ZKMX 3LJUX 3X23A 3N7CA 2W2WA 4XWXA 1EVHA 1U5DA 2K00A 5LOPB 2W2XD 1UPQA 4Y94A 2CODA 1MK7B 5D3YA 1XR0B 1Y19B 2KUPA 3ODOA 1WVHA 2W2XC 2DKPA 3D8EA 1DBHA 1FOEA 5C79A 5HE2A 1BAKA 3SNHA 3BJIA 2K2JA 3QIJA 4A6HA 1MKEA 3DXEA 1DDVA 4ZRJA 1PLSA 2GJYA 3OANA 3PVLA 4HAZB 4PQ0A 1ZC4B 5FI0A 2YS3A 2DHKA 1V5UA 5DI9B 1I7AA 5JLJB 2QKLA 1GC7A 1NTVA 1ZSQA 2COCA 4DXAB 1QQGA 1XKEA 1H4RA 3SV1A 4A6FA 2Z4DA 2YVCA 1M7EA 5C16A 4HAUB 2DFKA 3HIEA 1V88A 2ELBA 1MK9B 2JP2A 5IRSA 5C6RA 2UVMA 2K2UA 2E2XA 5JHHA 2IYBA 4YL8A 4EJNA 1IRSA 4CHJA 2KGXB 3SYXA 4A6KA 3AJ4A 3VIAA 3MPXA 1KI1B 3NWFA 2K8EA 4YONA 3D8FA 2D4QA 2P8VA 1PMSA 2M38A 4GXBA 5JP4A 2Y8GA 2D11A 1P3RA 3RCPA 5I2MA 1UNRA 2X18A 1OQNA 1GC6A 1J0WA 4K2OA 2KR0A 1Z87A 4WVFB 3WYFB 1U2BA 4A6FB 5DHFB 5HE1A 2I5FA 1K5DB 3PG7A 3MDBC 1U5EA 3G9WA 4B6HA 4L1RA 2D9XA 3FEHA 2P0HA 1T77A 2G35A 1WGUA 2EMTA 3KZ1A 4WSFA 2OTXA 2LULA 3KRXA 2AEHA 3QWMA 2DYNA 2HE7A 2H7EA 3SO6A 3V5WA 2QKMA 2YT1A 1U5FA 2Q13A 5KCVA 2YSZA 3A58A 2XQNM 2J0JA 1MIZB 2N23A 4KHAA 4Z2NA 2ROVA 2LOXA 3CIKA 4MT7A 1X1FA 3BINA 5D3VA 1XCGA
chains in the Genus database with same CATH topology
2FJUB 3NWDA 5IRSA 2RRFA 3OHMB 4KHBA 4QJ5B 4OSNA 4DIXA 4QJ4B 3GYPA 2R2YA 2KR0A 4PQ0A 4Z2MB 2KIEA 5I2SA 2KUQA 2K49A 3TO1A 2KIGA 3FSSA 4GNKB 3GYOA 5LG4B 3A58A 4CSQA 4HSIA 3TVVA 5M4YB 1ZYIA 3NW8A 4OT1A 4QJ3B 4D6WA 4L1RA 4KHOA 3NWFA 2K8EA 3NWAA 4IOYX 2Z4DA 4QXAB 3U12A 4KHAA 2GCLA 4KHBB 2GCJA 4Z2NA 2Z14A 2YT2A 4GOUA 2ZKMX 2Z59A 3FVCA 4IFSA 2GUMA 2Z13A 5I2MA 3HIEA 3TW1A 2NBVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IRS A;  2KR0 A;  2Z59 A;  2Z4D A;  2R2Y A;  2NBV A; 
#chains in the Genus database with same CATH topology
 1P5T A;  3OHM B;  4K81 A;  4TYZ A;  5HE3 A;  4DX8 A;  1U5G A;  2EC1 A;  1KZ7 A;  2COA A;  4HSI A;  1DYN A;  5M4Y B;  1ZYI A;  2CY4 A;  3NW8 A;  1WI1 A;  3U8Z A;  3F0W A;  5LON B;  1MPH A;  1DDW A;  2GCJ A;  2D9V A;  2Y7B A;  3SUZ A;  1WG7 A;  2COF A;  2P0D A;  2IFS A;  2D9Z A;  3TFM A;  5KQ1 A;  5LG4 B;  4HAW B;  5CLQ B;  2D2Q A;  1MIX A;  1PFJ A;  3AU4 A;  4D0N B;  5L81 A;  4IOY X;  1X05 A;  2VRW B;  3ODW A;  1ZVR A;  4IFS A;  4GN1 A;  2Z0Q A;  1QC6 A;  4K2P A;  2YS5 A;  3ULB A;  4F7H A;  1GG3 A;  3M1I B;  4QJ5 B;  3DXD A;  5D27 A;  3F5R A;  1RRP B;  2H7D A;  3A8Q A;  3KY9 A;  3PVU A;  1UNP A;  4HDO A;  4HB0 B;  5DIF B;  3P7Z A;  2I1J A;  1DDM A;  1J19 A;  2ROZ B;  3PVW A;  1E5W A;  4OT1 A;  5C5B A;  1FB8 A;  3HW2 B;  3NSU A;  1UPR A;  1WJ1 A;  4HAX B;  4ZRI A;  4K17 A;  2NBV A;  3FM8 C;  4KHB A;  1LB1 A;  2DA0 A;  4PNK A;  2L1C A;  2LOZ A;  2KUQ A;  1X1G A;  1V5M A;  1SGH A;  2D9W A;  1TJ6 A;  2J0M A;  4WJ7 A;  4D6W A;  1AQC A;  3P6A A;  4C0A A;  3AU5 A;  3PSC A;  2Z0O A;  2V76 A;  1H10 A;  5DH9 B;  2Z59 A;  5DHA B;  1B55 A;  2YS1 A;  4A5K A;  3O96 A;  3UZT A;  1WJM A;  3HQC A;  3A8P A;  4KAX B;  4HB4 B;  4CYE A;  2AL6 A;  2OQB A;  2RVB B;  1K5G B;  5C5B B;  2KIE A;  1X86 A;  1ZC3 B;  2DX5 A;  2K49 A;  4H8S A;  2ADZ A;  3VOQ A;  3TO1 A;  5J3T A;  2ZPY A;  3TVV A;  1EF1 A;  2DLW A;  1Q67 A;  4NSW A;  3NWA A;  3PZD A;  1FHW A;  1FHO A;  4EKU A;  4KHB B;  1TQZ A;  1I2H A;  4GOU A;  2UZS A;  3B77 A;  2RNR B;  2RSG A;  5CLL B;  1MAI A;  1FAO A;  1SHC A;  4HB3 B;  1V61 A;  2PZ1 A;  1W1G A;  2EMS A;  4GPT B;  4CHM A;  2MDX A;  3ML4 A;  4HDQ A;  4L6E A;  1UNQ A;  2DKQ A;  4KHO A;  4HAY B;  1UEF A;  2Z0P A;  1NI2 A;  4DX9 0;  1NU2 A;  1EGX A;  2Z13 A;  4HAT B;  3WA0 A;  1KZG A;  1P6S A;  2D10 A;  4TKN A;  3DXC A;  2R2Y A;  5D3W A;  4KVG B;  1MI1 A;  1W1H A;  2LKO A;  5EFX A;  4MY6 A;  1BWN A;  3T06 A;  5FI1 A;  4NY0 A;  1TXD A;  4ZRK A;  1FGY A;  1WGQ A;  2GCL A;  1LW3 A;  3HSA A;  1N3H A;  1U27 A;  2RUK B;  4DBB A;  2DHI A;  4MK0 A;  5J3Q A;  2J0K A;  2FJU B;  2N0Y A;  3U7D A;  1BTK A;  1XX0 A;  2VKI A;  2GS0 A;  3ULC A;  4Z2M B;  2DYQ A;  2HTH B;  2R0D A;  5D3X A;  2BCJ A;  4EMO A;  3GYO A;  1OY2 A;  3QBV B;  2MKR A;  1AWE A;  2KCJ A;  4HAV B;  4HB2 B;  2I1K A;  4GMV A;  1EAZ A;  5HE0 A;  1V5P A;  1FGZ A;  1BTN A;  3KSY A;  2J59 M;  1XOD A;  2RLO A;  3TCA A;  5J3Y A;  4IAP A;  1NTY A;  2D9Y A;  3TW1 A;  2EJ8 A;  2RGN B;  2DTC A;  2YRY A;  3PEG A;  5I2S A;  3IVF A;  4GMX B;  3DCX A;  4HHV A;  2KIG A;  2MFQ A;  4GNK B;  2CAY A;  4F7G A;  1OMW A;  5JHG A;  1X11 A;  4P7I A;  2I5C A;  2DX1 A;  4QXA B;  4BBK A;  2ELA A;  2LG1 A;  2Z14 A;  3D8D A;  3PP2 A;  2NZ8 B;  3NWD A;  1ZM0 A;  4GZU A;  1Y5O A;  2CY5 A;  2RRF A;  1RJ2 A;  2L2I A;  3ODX A;  4OSN A;  4DIX A;  2FJL A;  1U29 A;  3CXB B;  1DRO A;  2LYD A;  5GOW B;  1V89 A;  3FSS A;  1M7R A;  4CSQ A;  3KRW A;  1FHX A;  2YT0 A;  2MWN B;  2NMB A;  2VSZ A;  1ISN A;  2YT2 A;  3FVC A;  2YF0 A;  2GUM A;  2M14 A;  3ZDT A;  3HK0 A;  1XD4 A;  2DHJ A;  3ZVR A;  4QJ4 B;  3GYP A;  2CRF A;  2P0F A;  3A98 B;  2R09 A;  4F7U P;  4QJ3 B;  1W1D A;  2UZR A;  2Y8F A;  3U12 A;  5KQ4 A;  2DN6 A;  2ZKM X;  3LJU X;  3X23 A;  3N7C A;  2W2W A;  4XWX A;  1EVH A;  1U5D A;  2K00 A;  5LOP B;  2W2X D;  1UPQ A;  4Y94 A;  2COD A;  1MK7 B;  5D3Y A;  1XR0 B;  1Y19 B;  2KUP A;  3ODO A;  1WVH A;  2W2X C;  2DKP A;  3D8E A;  1DBH A;  1FOE A;  5C79 A;  5HE2 A;  1BAK A;  3SNH A;  3BJI A;  2K2J A;  3QIJ A;  4A6H A;  1MKE A;  3DXE A;  1DDV A;  4ZRJ A;  1PLS A;  2GJY A;  3OAN A;  3PVL A;  4HAZ B;  4PQ0 A;  1ZC4 B;  5FI0 A;  2YS3 A;  2DHK A;  1V5U A;  5DI9 B;  1I7A A;  5JLJ B;  2QKL A;  1GC7 A;  1NTV A;  1ZSQ A;  2COC A;  4DXA B;  1QQG A;  1XKE A;  1H4R A;  3SV1 A;  4A6F A;  2Z4D A;  2YVC A;  1M7E A;  5C16 A;  4HAU B;  2DFK A;  3HIE A;  1V88 A;  2ELB A;  1MK9 B;  2JP2 A;  5IRS A;  5C6R A;  2UVM A;  2K2U A;  2E2X A;  5JHH A;  2IYB A;  4YL8 A;  4EJN A;  1IRS A;  4CHJ A;  2KGX B;  3SYX A;  4A6K A;  3AJ4 A;  3VIA A;  3MPX A;  1KI1 B;  3NWF A;  2K8E A;  4YON A;  3D8F A;  2D4Q A;  2P8V A;  1PMS A;  2M38 A;  4GXB A;  5JP4 A;  2Y8G A;  2D11 A;  1P3R A;  3RCP A;  5I2M A;  1UNR A;  2X18 A;  1OQN A;  1GC6 A;  1J0W A;  4K2O A;  2KR0 A;  1Z87 A;  4WVF B;  3WYF B;  1U2B A;  4A6F B;  5DHF B;  5HE1 A;  2I5F A;  1K5D B;  3PG7 A;  3MDB C;  1U5E A;  3G9W A;  4B6H A;  4L1R A;  2D9X A;  3FEH A;  2P0H A;  1T77 A;  2G35 A;  1WGU A;  2EMT A;  3KZ1 A;  4WSF A;  2OTX A;  2LUL A;  3KRX A;  2AEH A;  3QWM A;  2DYN A;  2HE7 A;  2H7E A;  3SO6 A;  3V5W A;  2QKM A;  2YT1 A;  1U5F A;  2Q13 A;  5KCV A;  2YSZ A;  3A58 A;  2XQN M;  2J0J A;  1MIZ B;  2N23 A;  4KHA A;  4Z2N A;  2ROV A;  2LOX A;  3CIK A;  4MT7 A;  1X1F A;  3BIN A;  5D3V A;  1XCG A; 
#chains in the Genus database with same CATH homology
 2FJU B;  3NWD A;  5IRS A;  2RRF A;  3OHM B;  4KHB A;  4QJ5 B;  4OSN A;  4DIX A;  4QJ4 B;  3GYP A;  2R2Y A;  2KR0 A;  4PQ0 A;  4Z2M B;  2KIE A;  5I2S A;  2KUQ A;  2K49 A;  3TO1 A;  2KIG A;  3FSS A;  4GNK B;  3GYO A;  5LG4 B;  3A58 A;  4CSQ A;  4HSI A;  3TVV A;  5M4Y B;  1ZYI A;  3NW8 A;  4OT1 A;  4QJ3 B;  4D6W A;  4L1R A;  4KHO A;  3NWF A;  2K8E A;  3NWA A;  4IOY X;  2Z4D A;  4QXA B;  3U12 A;  4KHA A;  2GCL A;  4KHB B;  2GCJ A;  4Z2N A;  2Z14 A;  2YT2 A;  4GOU A;  2ZKM X;  2Z59 A;  3FVC A;  4IFS A;  2GUM A;  2Z13 A;  5I2M A;  3HIE A;  3TW1 A;  2NBV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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