1LB1 | Genus

Total Genus 116

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	116
sequence length	330
structure length	324
Chain Sequence	EEEESLAILRRHVMNELLDTERAYVEELLCVLEGYAAEMDNPLMAHLISTGLQNKKNILFGNMEEIYHFHNRIFLRELESCIDCPELVGRCFLERMEEFQIYEKYCQNKPRSESLWRQCSDCPFFQECQKKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSKHCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKKGLARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMTAVGITENVKGDTKKFEIWYNAREEVYIIQAPTPEIKAAWVNEIRKVLTSQLQACR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Signaling protein
source organism	Mus musculus
publication title	Structural basis for the selective activation of Rho GTPases by Dbl exchange factors. pubmed doi rcsb
molecule keywords	Guanine nucleotide exchange factor DBS
total genus	116
structure length	324
sequence length	330
chains with identical sequence	C, E, G
ec nomenclature
pdb deposition date	2002-04-01

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00169	PH	PH domain
A	PF00621	RhoGEF	RhoGEF domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.900.10	Mainly Alpha	Up-down Bundle	Dbl Homology Domain; Chain A	Dbl homology (DH) domain	1lb1A01
2.30.29.30	Mainly Beta	Roll	PH-domain like	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	1lb1A02

4IOYX 5C5BA 2VKIA 1FB8A 1EAZA 2J59M 4ZRIA 2W2WA 2R0DA 1U2BA 2ROVA 4KHBB 2D11A 2EC1A 2ADZA 3P6AA 2DN6A 3D8FA 4HAVB 1QQGA 4HAUB 4WSFA 2ELAA 2I5FA 3A8PA 4EJNA 1RRPB 1NI2A 2GCJA 1UPRA 5JP4A 3AJ4A 2I1KA 2H7EA 2P8VA 1H4RA 5D3YA 2RNRB 1N3HA 5DHFB 4K81A 2DHKA 4DBBA 1WJMA 2YRYA 2LYDA 2VSZA 1Y5OA 4HAYB 2YF0A 3RCPA 2KGXB 3D8EA 1ZVRA 1OY2A 1BY1A 5DI9B 2MFQA 4DXAB 1I7AA 1UEFA 3ULCA 3A8QA 1KZ7A 1WGUA 2D2QA 2IFSA 3BJIA 2DHJA 4HB3B 1U5EA 1NTYA 3VOQA 1I2HA 2P0HA 3OANA 1AQCA 1Q67A 1EGXA 2R09A 2D9VA 2X18A 2COFA 2RGNB 2V76A 4HATB 1MIXA 1MKEA 1P3RA 2J0JA 3T06A 1Z87A 2LOXA 4A6FA 1UNQA 4A6KA 1K5GB 5C16A 3G9WA 3LJUX 1PLSA 2P0DA 4HDOA 5C5BB 5KQ1A 2YSZA 3MPXA 5J3QA 4MT7A 3BINA 1DDVA 4PNKA 3TCAA 1BTKA 2D9YA 3DXCA 1M7RA 3DXEA 2D9XA 3ODWA 2KCJA 3QWMA 4F7GA 1EF1A 2RLOA 2EMSA 1XX0A 2GS0A 2KR9A 1X11A 3CIKA 3U8ZA 2N23A 5DIFB 4ZRJA 4GXBA 1B55A 1LW3A 1W1DA 2Z0OA 3ZDTA 1WGQA 5JHGA 3N7CA 4YONA 2OTXA 2H7DA 2EMTA 4GMVA 2Z0QA 3SV1A 2M38A 3TFMA 3O96A 2CY4A 2GCLA 4GYVA 2XQNM 2KUPA 2IYBA 1SGHA 1U27A 3A98B 4H8SA 4HB0B 4TYZA 1KZGA 2BCJA 2CODA 2M14A 4A5KA 3X23A 1J19A 1FGZA 1MK7B 3GYOA 2P0FA 1F5XA 2JP2A 2J0KA 4HDQA 2FJLA 4YL8A 2DYQA 4HAXB 2N0YA 3F5RA 1TQZA 4PQ0A 3PVWA 1V88A 1E5WA 2Y7BA 2YS1A 4C0AA 1FHXA 3SUZA 1AWEA 4GPTB 4DX8A 4K17A 4HB4B 4IFSA 1M7EA 1U5DA 2DYNA 3PVLA 5HE2A 1U29A 1ISNA 3KSYA 1U5FA 2YS5A 3WYFB 4A6HA 3GYPA 1TJ6A 2I5CA 1DROA 1PMSA 1U5GA 1V89A 2DA0A 1FHWA 2K2UA 2YT0A 1MAIA 3PZDA 2DHIA 2UVMA 5KQ4A 1GC6A 3QIJA 4CHMA 4HAZB 1IRSA 1J0WA 3TVVA 3HW2B 4NSWA 3U7DA 3QBVB 4F7HA 2UZRA 2DKPA 2D10A 4GN1A 2HTHB 3FSSA 4P7IA 3SYXA 5JLJB 2GJYA 2DX5A 4HHVA 1XR0B 2MDXA 2L1CA 3ML4A 2NMBA 3SNHA 2YT1A 2DX1A 2UZSA 4WJ7A 1GC7A 2DTCA 5D3VA 3SO6A 4GOUA 1W1HA 3IVFA 1XD4A 1TXDA 1RJ2A 3PVUA 4Y94A 3UZTA 1SHCA 2K2JA 1UPQA 4TKNA 1XCGA 3GF9A 1MPHA 2AEHA 4HAWB 2Y8GA 1DBHA 1WG7A 1X86A 2LG1A 3CXBB 4KVGB 1ZC4B 1WI1A 2DFKA 5J3YA 2I1JA 2CAYA 4GZUA 2VRWB 2E2XA 3AU4A 5FI1A 1EVHA 1X1GA 2D9ZA 3ODXA 1V5PA 1QC6A 5FI0A 5DHAB 1WJ1A 1V5MA 3HK0A 2K00A 1FOEA 4XWXA 3PEGA 1DDWA 2DLWA 2LOZA 4BBKA 1OMWA 5JHHA 4A6FB 3WA0A 3F0WA 5HE0A 1FGYA 2ROZB 5KCVA 1ZC3B 2DKQA 4WVFB 5D27A 4EKUA 4D0OA 1NU2A 2D4QA 2AL6A 1XODA 4B6HA 3NSUA 2W2XC 2YS3A 2COCA 1GG3A 3M1IB 3KRXA 1FHOA 4F7UP 2QKMA 1WVHA 5LONB 5D3XA 3ZVRA 1XKEA 4L6EA 1V5UA 5L81A 4CYEA 3KY9A 1BWNA 1LB1A 3D8DA 2COAA 3MDBC 2G35A 2LKOA 2MKRA 1W1GA 4HB2B 3VIAA 2HE7A 1UNRA 1P6SA 4D0NB 1FAOA 4Z2NA 1MIZB 1ZSQA 4KAXB 1UNPA 4EMOA 1X1FA 5DH9B 2NZ8B 2OQBA 3ULBA 3EO2A 2Z0PA 1DDMA 3PP2A 4K2OA 2Q13A 2Y8FA 1MK9B 1BAKA 4Z2MB 3KRWA 1V61A 4MK0A 1KI1B 1PFJA 3HQCA 2D9WA 2CRFA 3AU5A 4KHAA 3V5WA 4NY0A 3TW1A 1P5TA 5HE3A 1DYNA 1OQNA 2LULA 2L2IA 2RUKB 4DX90 5C79A 3P7ZA 3DXDA 3KZ1A 5C6RA 2RVBB 2W2XD 1NTVA 5LOPB 4KHOA 3ODOA 2QKLA 4IAPA 2EJ8A 1ZM0A 5J3TA 5D3WA 5GOWB 5HE1A 2RSGA 4GMXB 4K2PA 2YVCA 1H10A 4CHJA 3FM8C 3FEHA 5CLQB 1K5DB 4MY6A 2PZ1A 5CLLB 1X05A 2MWNB 5EFXA 2ZPYA 3JV3A 3PG7A 3TO1A 3PSCA 2ELBA 2J0MA 4ZRKA 1BTNA 2CY5A 1Y19B
chains in the Genus database with same CATH superfamily

4IOYX 5C5BA 3A58A 1T77A 2VKIA 1FB8A 1EAZA 2J59M 4ZRIA 2W2WA 2R0DA 1U2BA 2ROVA 4KHBB 2D11A 2EC1A 2R2YA 2ADZA 3P6AA 2DN6A 3D8FA 4HAVB 1QQGA 5LG4B 2RRFA 4HAUB 4WSFA 2ELAA 1MI1A 2I5FA 3A8PA 4EJNA 1RRPB 4QJ5B 1NI2A 2GCJA 4OT1A 1UPRA 5JP4A 3AJ4A 2I1KA 2H7EA 2P8VA 1H4RA 5D3YA 2RNRB 1N3HA 3NWAA 4K81A 5DHFB 2DHKA 4GNKB 1WJMA 4DBBA 2YRYA 2LYDA 2VSZA 1Y5OA 4HAYB 2YF0A 3RCPA 2KGXB 3D8EA 1ZVRA 1OY2A 1BY1A 5DI9B 2MFQA 4DXAB 1I7AA 1UEFA 3ULCA 3A8QA 1KZ7A 1WGUA 2D2QA 2IFSA 3BJIA 2DHJA 3OHMB 4HB3B 1U5EA 1NTYA 3VOQA 1I2HA 2P0HA 3OANA 1AQCA 1Q67A 1EGXA 2R09A 3HIEA 2D9VA 2X18A 2COFA 2RGNB 2V76A 4HATB 1MIXA 1MKEA 1P3RA 2J0JA 3T06A 1Z87A 2LOXA 4A6FA 1UNQA 4A6KA 1K5GB 5C16A 3G9WA 3LJUX 1PLSA 2P0DA 4HDOA 5C5BB 4CSQA 2YSZA 3MPXA 5KQ1A 5J3QA 4MT7A 3BINA 1DDVA 4PNKA 3TCAA 1BTKA 2D9YA 3DXCA 1M7RA 3DXEA 2D9XA 3ODWA 2KCJA 3QWMA 2GUMA 4F7GA 1EF1A 2RLOA 2EMSA 1XX0A 3NW8A 2GS0A 2KR9A 1X11A 3CIKA 3U8ZA 2N23A 1ZYIA 5DIFB 4ZRJA 4GXBA 3HSAA 1B55A 1LW3A 1W1DA 2Z0OA 3ZDTA 1WGQA 5JHGA 3N7CA 4YONA 2OTXA 2H7DA 2EMTA 4GMVA 2Z0QA 3SV1A 2M38A 3TFMA 3O96A 2CY4A 2GCLA 4GYVA 2XQNM 2KUPA 2IYBA 1SGHA 1U27A 3B77A 3A98B 4H8SA 4HB0B 4TYZA 1KZGA 2BCJA 2CODA 2M14A 4A5KA 3X23A 1J19A 1FGZA 1MK7B 2KIGA 3GYOA 2P0FA 1F5XA 2JP2A 2J0KA 4HDQA 2FJLA 4YL8A 2DYQA 4HAXB 2N0YA 3F5RA 1TQZA 4HSIA 4PQ0A 3PVWA 2FJUB 1V88A 1E5WA 4QJ4B 2Y7BA 2YS1A 4C0AA 1FHXA 3SUZA 1AWEA 4GPTB 4DX8A 4K17A 2KR0A 4HB4B 4IFSA 1M7EA 1U5DA 2DYNA 3NWFA 3PVLA 5HE2A 1U29A 1ISNA 3KSYA 1U5FA 2YS5A 3WYFB 4A6HA 3GYPA 1TJ6A 2I5CA 2Z4DA 1DROA 1PMSA 1U5GA 1V89A 2DA0A 1FHWA 2K2UA 2YT0A 1MAIA 3PZDA 2DHIA 5I2MA 2Z14A 2UVMA 5KQ4A 1GC6A 3QIJA 4CHMA 4HAZB 3NWDA 1IRSA 1J0WA 3TVVA 3HW2B 4NSWA 3U7DA 3QBVB 4F7HA 2UZRA 2DKPA 2D10A 4GN1A 2HTHB 3FSSA 4P7IA 4KHBA 3SYXA 5JLJB 2GJYA 2DX5A 4HHVA 1XR0B 2MDXA 2L1CA 3ML4A 2NMBA 3SNHA 2YT1A 5M4YB 2DX1A 2UZSA 4WJ7A 1GC7A 2DTCA 5D3VA 3SO6A 4GOUA 1W1HA 3IVFA 2KUQA 1XD4A 1TXDA 1RJ2A 3PVUA 4Y94A 3UZTA 1SHCA 2K2JA 1UPQA 4TKNA 1XCGA 3GF9A 1MPHA 2KIEA 2AEHA 4HAWB 2Y8GA 1DBHA 1WG7A 1X86A 2LG1A 3CXBB 4KVGB 1ZC4B 1WI1A 2DFKA 5J3YA 2I1JA 2CAYA 4GZUA 2VRWB 2E2XA 3AU4A 5FI1A 1EVHA 1X1GA 2D9ZA 3ODXA 1V5PA 1QC6A 2Z13A 5FI0A 5DHAB 1WJ1A 1V5MA 3HK0A 2K00A 1FOEA 4XWXA 3PEGA 1DDWA 2DLWA 2LOZA 2NBVA 5IRSA 4BBKA 1OMWA 5JHHA 4A6FB 3WA0A 4D6WA 3F0WA 5HE0A 1FGYA 2ROZB 5KCVA 1ZC3B 2DKQA 4WVFB 5D27A 4EKUA 4D0OA 4OSNA 1NU2A 4DIXA 2K8EA 2D4QA 2AL6A 1XODA 4B6HA 3NSUA 2W2XC 2YS3A 2COCA 1GG3A 3M1IB 3KRXA 1FHOA 4F7UP 2QKMA 1WVHA 5LONB 5D3XA 3ZVRA 1XKEA 4L6EA 1V5UA 5L81A 4CYEA 3KY9A 1BWNA 1LB1A 3D8DA 2COAA 3MDBC 5I2SA 2G35A 2ZKMX 2LKOA 2MKRA 1W1GA 4HB2B 3VIAA 2HE7A 4QXAB 1UNRA 1P6SA 4D0NB 3DCXA 1FAOA 4Z2NA 1MIZB 1ZSQA 4KAXB 1UNPA 4EMOA 1X1FA 5DH9B 2NZ8B 2OQBA 3ULBA 3EO2A 2Z0PA 1DDMA 3FVCA 3PP2A 4K2OA 2Q13A 2Y8FA 1MK9B 1BAKA 4Z2MB 3KRWA 1V61A 4MK0A 1KI1B 1PFJA 2K49A 3HQCA 2D9WA 2CRFA 3AU5A 4KHAA 3V5WA 4NY0A 3TW1A 1P5TA 4L1RA 5HE3A 1DYNA 1OQNA 2LULA 2L2IA 2RUKB 3U12A 4DX90 5C79A 3P7ZA 3DXDA 3KZ1A 5C6RA 2RVBB 2W2XD 1NTVA 5LOPB 4KHOA 3ODOA 2QKLA 4IAPA 2EJ8A 1ZM0A 2YT2A 5J3TA 5D3WA 5GOWB 5HE1A 2RSGA 4GMXB 4QJ3B 4K2PA 2YVCA 1H10A 4CHJA 3FM8C 3FEHA 5CLQB 1K5DB 2Z59A 4MY6A 2PZ1A 5CLLB 1X05A 2MWNB 5EFXA 2ZPYA 3JV3A 3PG7A 3TO1A 3PSCA 2ELBA 2J0MA 4ZRKA 1BTNA 2CY5A 1Y19B
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4IOY X;  5C5B A;  2VKI A;  1FB8 A;  1EAZ A;  2J59 M;  4ZRI A;  2W2W A;  2R0D A;  1U2B A;  2ROV A;  4KHB B;  2D11 A;  2EC1 A;  2ADZ A;  3P6A A;  2DN6 A;  3D8F A;  4HAV B;  1QQG A;  4HAU B;  4WSF A;  2ELA A;  2I5F A;  3A8P A;  4EJN A;  1RRP B;  1NI2 A;  2GCJ A;  1UPR A;  5JP4 A;  3AJ4 A;  2I1K A;  2H7E A;  2P8V A;  1H4R A;  5D3Y A;  2RNR B;  1N3H A;  5DHF B;  4K81 A;  2DHK A;  4DBB A;  1WJM A;  2YRY A;  2LYD A;  2VSZ A;  1Y5O A;  4HAY B;  2YF0 A;  3RCP A;  2KGX B;  3D8E A;  1ZVR A;  1OY2 A;  1BY1 A;  5DI9 B;  2MFQ A;  4DXA B;  1I7A A;  1UEF A;  3ULC A;  3A8Q A;  1KZ7 A;  1WGU A;  2D2Q A;  2IFS A;  3BJI A;  2DHJ A;  4HB3 B;  1U5E A;  1NTY A;  3VOQ A;  1I2H A;  2P0H A;  3OAN A;  1AQC A;  1Q67 A;  1EGX A;  2R09 A;  2D9V A;  2X18 A;  2COF A;  2RGN B;  2V76 A;  4HAT B;  1MIX A;  1MKE A;  1P3R A;  2J0J A;  3T06 A;  1Z87 A;  2LOX A;  4A6F A;  1UNQ A;  4A6K A;  1K5G B;  5C16 A;  3G9W A;  3LJU X;  1PLS A;  2P0D A;  4HDO A;  5C5B B;  5KQ1 A;  2YSZ A;  3MPX A;  5J3Q A;  4MT7 A;  3BIN A;  1DDV A;  4PNK A;  3TCA A;  1BTK A;  2D9Y A;  3DXC A;  1M7R A;  3DXE A;  2D9X A;  3ODW A;  2KCJ A;  3QWM A;  4F7G A;  1EF1 A;  2RLO A;  2EMS A;  1XX0 A;  2GS0 A;  2KR9 A;  1X11 A;  3CIK A;  3U8Z A;  2N23 A;  5DIF B;  4ZRJ A;  4GXB A;  1B55 A;  1LW3 A;  1W1D A;  2Z0O A;  3ZDT A;  1WGQ A;  5JHG A;  3N7C A;  4YON A;  2OTX A;  2H7D A;  2EMT A;  4GMV A;  2Z0Q A;  3SV1 A;  2M38 A;  3TFM A;  3O96 A;  2CY4 A;  2GCL A;  4GYV A;  2XQN M;  2KUP A;  2IYB A;  1SGH A;  1U27 A;  3A98 B;  4H8S A;  4HB0 B;  4TYZ A;  1KZG A;  2BCJ A;  2COD A;  2M14 A;  4A5K A;  3X23 A;  1J19 A;  1FGZ A;  1MK7 B;  3GYO A;  2P0F A;  1F5X A;  2JP2 A;  2J0K A;  4HDQ A;  2FJL A;  4YL8 A;  2DYQ A;  4HAX B;  2N0Y A;  3F5R A;  1TQZ A;  4PQ0 A;  3PVW A;  1V88 A;  1E5W A;  2Y7B A;  2YS1 A;  4C0A A;  1FHX A;  3SUZ A;  1AWE A;  4GPT B;  4DX8 A;  4K17 A;  4HB4 B;  4IFS A;  1M7E A;  1U5D A;  2DYN A;  3PVL A;  5HE2 A;  1U29 A;  1ISN A;  3KSY A;  1U5F A;  2YS5 A;  3WYF B;  4A6H A;  3GYP A;  1TJ6 A;  2I5C A;  1DRO A;  1PMS A;  1U5G A;  1V89 A;  2DA0 A;  1FHW A;  2K2U A;  2YT0 A;  1MAI A;  3PZD A;  2DHI A;  2UVM A;  5KQ4 A;  1GC6 A;  3QIJ A;  4CHM A;  4HAZ B;  1IRS A;  1J0W A;  3TVV A;  3HW2 B;  4NSW A;  3U7D A;  3QBV B;  4F7H A;  2UZR A;  2DKP A;  2D10 A;  4GN1 A;  2HTH B;  3FSS A;  4P7I A;  3SYX A;  5JLJ B;  2GJY A;  2DX5 A;  4HHV A;  1XR0 B;  2MDX A;  2L1C A;  3ML4 A;  2NMB A;  3SNH A;  2YT1 A;  2DX1 A;  2UZS A;  4WJ7 A;  1GC7 A;  2DTC A;  5D3V A;  3SO6 A;  4GOU A;  1W1H A;  3IVF A;  1XD4 A;  1TXD A;  1RJ2 A;  3PVU A;  4Y94 A;  3UZT A;  1SHC A;  2K2J A;  1UPQ A;  4TKN A;  1XCG A;  3GF9 A;  1MPH A;  2AEH A;  4HAW B;  2Y8G A;  1DBH A;  1WG7 A;  1X86 A;  2LG1 A;  3CXB B;  4KVG B;  1ZC4 B;  1WI1 A;  2DFK A;  5J3Y A;  2I1J A;  2CAY A;  4GZU A;  2VRW B;  2E2X A;  3AU4 A;  5FI1 A;  1EVH A;  1X1G A;  2D9Z A;  3ODX A;  1V5P A;  1QC6 A;  5FI0 A;  5DHA B;  1WJ1 A;  1V5M A;  3HK0 A;  2K00 A;  1FOE A;  4XWX A;  3PEG A;  1DDW A;  2DLW A;  2LOZ A;  4BBK A;  1OMW A;  5JHH A;  4A6F B;  3WA0 A;  3F0W A;  5HE0 A;  1FGY A;  2ROZ B;  5KCV A;  1ZC3 B;  2DKQ A;  4WVF B;  5D27 A;  4EKU A;  4D0O A;  1NU2 A;  2D4Q A;  2AL6 A;  1XOD A;  4B6H A;  3NSU A;  2W2X C;  2YS3 A;  2COC A;  1GG3 A;  3M1I B;  3KRX A;  1FHO A;  4F7U P;  2QKM A;  1WVH A;  5LON B;  5D3X A;  3ZVR A;  1XKE A;  4L6E A;  1V5U A;  5L81 A;  4CYE A;  3KY9 A;  1BWN A;  1LB1 A;  3D8D A;  2COA A;  3MDB C;  2G35 A;  2LKO A;  2MKR A;  1W1G A;  4HB2 B;  3VIA A;  2HE7 A;  1UNR A;  1P6S A;  4D0N B;  1FAO A;  4Z2N A;  1MIZ B;  1ZSQ A;  4KAX B;  1UNP A;  4EMO A;  1X1F A;  5DH9 B;  2NZ8 B;  2OQB A;  3ULB A;  3EO2 A;  2Z0P A;  1DDM A;  3PP2 A;  4K2O A;  2Q13 A;  2Y8F A;  1MK9 B;  1BAK A;  4Z2M B;  3KRW A;  1V61 A;  4MK0 A;  1KI1 B;  1PFJ A;  3HQC A;  2D9W A;  2CRF A;  3AU5 A;  4KHA A;  3V5W A;  4NY0 A;  3TW1 A;  1P5T A;  5HE3 A;  1DYN A;  1OQN A;  2LUL A;  2L2I A;  2RUK B;  4DX9 0;  5C79 A;  3P7Z A;  3DXD A;  3KZ1 A;  5C6R A;  2RVB B;  2W2X D;  1NTV A;  5LOP B;  4KHO A;  3ODO A;  2QKL A;  4IAP A;  2EJ8 A;  1ZM0 A;  5J3T A;  5D3W A;  5GOW B;  5HE1 A;  2RSG A;  4GMX B;  4K2P A;  2YVC A;  1H10 A;  4CHJ A;  3FM8 C;  3FEH A;  5CLQ B;  1K5D B;  4MY6 A;  2PZ1 A;  5CLL B;  1X05 A;  2MWN B;  5EFX A;  2ZPY A;  3JV3 A;  3PG7 A;  3TO1 A;  3PSC A;  2ELB A;  2J0M A;  4ZRK A;  1BTN A;  2CY5 A;  1Y19 B; 
#chains in the Genus database with same CATH topology
 4IOY X;  5C5B A;  3A58 A;  1T77 A;  2VKI A;  1FB8 A;  1EAZ A;  2J59 M;  4ZRI A;  2W2W A;  2R0D A;  1U2B A;  2ROV A;  4KHB B;  2D11 A;  2EC1 A;  2R2Y A;  2ADZ A;  3P6A A;  2DN6 A;  3D8F A;  4HAV B;  1QQG A;  5LG4 B;  2RRF A;  4HAU B;  4WSF A;  2ELA A;  1MI1 A;  2I5F A;  3A8P A;  4EJN A;  1RRP B;  4QJ5 B;  1NI2 A;  2GCJ A;  4OT1 A;  1UPR A;  5JP4 A;  3AJ4 A;  2I1K A;  2H7E A;  2P8V A;  1H4R A;  5D3Y A;  2RNR B;  1N3H A;  3NWA A;  4K81 A;  5DHF B;  2DHK A;  4GNK B;  1WJM A;  4DBB A;  2YRY A;  2LYD A;  2VSZ A;  1Y5O A;  4HAY B;  2YF0 A;  3RCP A;  2KGX B;  3D8E A;  1ZVR A;  1OY2 A;  1BY1 A;  5DI9 B;  2MFQ A;  4DXA B;  1I7A A;  1UEF A;  3ULC A;  3A8Q A;  1KZ7 A;  1WGU A;  2D2Q A;  2IFS A;  3BJI A;  2DHJ A;  3OHM B;  4HB3 B;  1U5E A;  1NTY A;  3VOQ A;  1I2H A;  2P0H A;  3OAN A;  1AQC A;  1Q67 A;  1EGX A;  2R09 A;  3HIE A;  2D9V A;  2X18 A;  2COF A;  2RGN B;  2V76 A;  4HAT B;  1MIX A;  1MKE A;  1P3R A;  2J0J A;  3T06 A;  1Z87 A;  2LOX A;  4A6F A;  1UNQ A;  4A6K A;  1K5G B;  5C16 A;  3G9W A;  3LJU X;  1PLS A;  2P0D A;  4HDO A;  5C5B B;  4CSQ A;  2YSZ A;  3MPX A;  5KQ1 A;  5J3Q A;  4MT7 A;  3BIN A;  1DDV A;  4PNK A;  3TCA A;  1BTK A;  2D9Y A;  3DXC A;  1M7R A;  3DXE A;  2D9X A;  3ODW A;  2KCJ A;  3QWM A;  2GUM A;  4F7G A;  1EF1 A;  2RLO A;  2EMS A;  1XX0 A;  3NW8 A;  2GS0 A;  2KR9 A;  1X11 A;  3CIK A;  3U8Z A;  2N23 A;  1ZYI A;  5DIF B;  4ZRJ A;  4GXB A;  3HSA A;  1B55 A;  1LW3 A;  1W1D A;  2Z0O A;  3ZDT A;  1WGQ A;  5JHG A;  3N7C A;  4YON A;  2OTX A;  2H7D A;  2EMT A;  4GMV A;  2Z0Q A;  3SV1 A;  2M38 A;  3TFM A;  3O96 A;  2CY4 A;  2GCL A;  4GYV A;  2XQN M;  2KUP A;  2IYB A;  1SGH A;  1U27 A;  3B77 A;  3A98 B;  4H8S A;  4HB0 B;  4TYZ A;  1KZG A;  2BCJ A;  2COD A;  2M14 A;  4A5K A;  3X23 A;  1J19 A;  1FGZ A;  1MK7 B;  2KIG A;  3GYO A;  2P0F A;  1F5X A;  2JP2 A;  2J0K A;  4HDQ A;  2FJL A;  4YL8 A;  2DYQ A;  4HAX B;  2N0Y A;  3F5R A;  1TQZ A;  4HSI A;  4PQ0 A;  3PVW A;  2FJU B;  1V88 A;  1E5W A;  4QJ4 B;  2Y7B A;  2YS1 A;  4C0A A;  1FHX A;  3SUZ A;  1AWE A;  4GPT B;  4DX8 A;  4K17 A;  2KR0 A;  4HB4 B;  4IFS A;  1M7E A;  1U5D A;  2DYN A;  3NWF A;  3PVL A;  5HE2 A;  1U29 A;  1ISN A;  3KSY A;  1U5F A;  2YS5 A;  3WYF B;  4A6H A;  3GYP A;  1TJ6 A;  2I5C A;  2Z4D A;  1DRO A;  1PMS A;  1U5G A;  1V89 A;  2DA0 A;  1FHW A;  2K2U A;  2YT0 A;  1MAI A;  3PZD A;  2DHI A;  5I2M A;  2Z14 A;  2UVM A;  5KQ4 A;  1GC6 A;  3QIJ A;  4CHM A;  4HAZ B;  3NWD A;  1IRS A;  1J0W A;  3TVV A;  3HW2 B;  4NSW A;  3U7D A;  3QBV B;  4F7H A;  2UZR A;  2DKP A;  2D10 A;  4GN1 A;  2HTH B;  3FSS A;  4P7I A;  4KHB A;  3SYX A;  5JLJ B;  2GJY A;  2DX5 A;  4HHV A;  1XR0 B;  2MDX A;  2L1C A;  3ML4 A;  2NMB A;  3SNH A;  2YT1 A;  5M4Y B;  2DX1 A;  2UZS A;  4WJ7 A;  1GC7 A;  2DTC A;  5D3V A;  3SO6 A;  4GOU A;  1W1H A;  3IVF A;  2KUQ A;  1XD4 A;  1TXD A;  1RJ2 A;  3PVU A;  4Y94 A;  3UZT A;  1SHC A;  2K2J A;  1UPQ A;  4TKN A;  1XCG A;  3GF9 A;  1MPH A;  2KIE A;  2AEH A;  4HAW B;  2Y8G A;  1DBH A;  1WG7 A;  1X86 A;  2LG1 A;  3CXB B;  4KVG B;  1ZC4 B;  1WI1 A;  2DFK A;  5J3Y A;  2I1J A;  2CAY A;  4GZU A;  2VRW B;  2E2X A;  3AU4 A;  5FI1 A;  1EVH A;  1X1G A;  2D9Z A;  3ODX A;  1V5P A;  1QC6 A;  2Z13 A;  5FI0 A;  5DHA B;  1WJ1 A;  1V5M A;  3HK0 A;  2K00 A;  1FOE A;  4XWX A;  3PEG A;  1DDW A;  2DLW A;  2LOZ A;  2NBV A;  5IRS A;  4BBK A;  1OMW A;  5JHH A;  4A6F B;  3WA0 A;  4D6W A;  3F0W A;  5HE0 A;  1FGY A;  2ROZ B;  5KCV A;  1ZC3 B;  2DKQ A;  4WVF B;  5D27 A;  4EKU A;  4D0O A;  4OSN A;  1NU2 A;  4DIX A;  2K8E A;  2D4Q A;  2AL6 A;  1XOD A;  4B6H A;  3NSU A;  2W2X C;  2YS3 A;  2COC A;  1GG3 A;  3M1I B;  3KRX A;  1FHO A;  4F7U P;  2QKM A;  1WVH A;  5LON B;  5D3X A;  3ZVR A;  1XKE A;  4L6E A;  1V5U A;  5L81 A;  4CYE A;  3KY9 A;  1BWN A;  1LB1 A;  3D8D A;  2COA A;  3MDB C;  5I2S A;  2G35 A;  2ZKM X;  2LKO A;  2MKR A;  1W1G A;  4HB2 B;  3VIA A;  2HE7 A;  4QXA B;  1UNR A;  1P6S A;  4D0N B;  3DCX A;  1FAO A;  4Z2N A;  1MIZ B;  1ZSQ A;  4KAX B;  1UNP A;  4EMO A;  1X1F A;  5DH9 B;  2NZ8 B;  2OQB A;  3ULB A;  3EO2 A;  2Z0P A;  1DDM A;  3FVC A;  3PP2 A;  4K2O A;  2Q13 A;  2Y8F A;  1MK9 B;  1BAK A;  4Z2M B;  3KRW A;  1V61 A;  4MK0 A;  1KI1 B;  1PFJ A;  2K49 A;  3HQC A;  2D9W A;  2CRF A;  3AU5 A;  4KHA A;  3V5W A;  4NY0 A;  3TW1 A;  1P5T A;  4L1R A;  5HE3 A;  1DYN A;  1OQN A;  2LUL A;  2L2I A;  2RUK B;  3U12 A;  4DX9 0;  5C79 A;  3P7Z A;  3DXD A;  3KZ1 A;  5C6R A;  2RVB B;  2W2X D;  1NTV A;  5LOP B;  4KHO A;  3ODO A;  2QKL A;  4IAP A;  2EJ8 A;  1ZM0 A;  2YT2 A;  5J3T A;  5D3W A;  5GOW B;  5HE1 A;  2RSG A;  4GMX B;  4QJ3 B;  4K2P A;  2YVC A;  1H10 A;  4CHJ A;  3FM8 C;  3FEH A;  5CLQ B;  1K5D B;  2Z59 A;  4MY6 A;  2PZ1 A;  5CLL B;  1X05 A;  2MWN B;  5EFX A;  2ZPY A;  3JV3 A;  3PG7 A;  3TO1 A;  3PSC A;  2ELB A;  2J0M A;  4ZRK A;  1BTN A;  2CY5 A;  1Y19 B; 
#chains in the Genus database with same CATH homology
 4IOY X;  5C5B A;  2VKI A;  1FB8 A;  1EAZ A;  2J59 M;  4ZRI A;  2W2W A;  2R0D A;  1U2B A;  2ROV A;  4KHB B;  2D11 A;  2EC1 A;  2ADZ A;  3P6A A;  2DN6 A;  3D8F A;  4HAV B;  1QQG A;  4HAU B;  4WSF A;  2ELA A;  2I5F A;  3A8P A;  4EJN A;  1RRP B;  1NI2 A;  2GCJ A;  1UPR A;  5JP4 A;  3AJ4 A;  2I1K A;  2H7E A;  2P8V A;  1H4R A;  5D3Y A;  2RNR B;  1N3H A;  5DHF B;  4K81 A;  2DHK A;  4DBB A;  1WJM A;  2YRY A;  2LYD A;  2VSZ A;  1Y5O A;  4HAY B;  2YF0 A;  3RCP A;  2KGX B;  3D8E A;  1ZVR A;  1OY2 A;  1BY1 A;  5DI9 B;  2MFQ A;  4DXA B;  1I7A A;  1UEF A;  3ULC A;  3A8Q A;  1KZ7 A;  1WGU A;  2D2Q A;  2IFS A;  3BJI A;  2DHJ A;  4HB3 B;  1U5E A;  1NTY A;  3VOQ A;  1I2H A;  2P0H A;  3OAN A;  1AQC A;  1Q67 A;  1EGX A;  2R09 A;  2D9V A;  2X18 A;  2COF A;  2RGN B;  2V76 A;  4HAT B;  1MIX A;  1MKE A;  1P3R A;  2J0J A;  3T06 A;  1Z87 A;  2LOX A;  4A6F A;  1UNQ A;  4A6K A;  1K5G B;  5C16 A;  3G9W A;  3LJU X;  1PLS A;  2P0D A;  4HDO A;  5C5B B;  5KQ1 A;  2YSZ A;  3MPX A;  5J3Q A;  4MT7 A;  3BIN A;  1DDV A;  4PNK A;  3TCA A;  1BTK A;  2D9Y A;  3DXC A;  1M7R A;  3DXE A;  2D9X A;  3ODW A;  2KCJ A;  3QWM A;  4F7G A;  1EF1 A;  2RLO A;  2EMS A;  1XX0 A;  2GS0 A;  2KR9 A;  1X11 A;  3CIK A;  3U8Z A;  2N23 A;  5DIF B;  4ZRJ A;  4GXB A;  1B55 A;  1LW3 A;  1W1D A;  2Z0O A;  3ZDT A;  1WGQ A;  5JHG A;  3N7C A;  4YON A;  2OTX A;  2H7D A;  2EMT A;  4GMV A;  2Z0Q A;  3SV1 A;  2M38 A;  3TFM A;  3O96 A;  2CY4 A;  2GCL A;  4GYV A;  2XQN M;  2KUP A;  2IYB A;  1SGH A;  1U27 A;  3A98 B;  4H8S A;  4HB0 B;  4TYZ A;  1KZG A;  2BCJ A;  2COD A;  2M14 A;  4A5K A;  3X23 A;  1J19 A;  1FGZ A;  1MK7 B;  3GYO A;  2P0F A;  1F5X A;  2JP2 A;  2J0K A;  4HDQ A;  2FJL A;  4YL8 A;  2DYQ A;  4HAX B;  2N0Y A;  3F5R A;  1TQZ A;  4PQ0 A;  3PVW A;  1V88 A;  1E5W A;  2Y7B A;  2YS1 A;  4C0A A;  1FHX A;  3SUZ A;  1AWE A;  4GPT B;  4DX8 A;  4K17 A;  4HB4 B;  4IFS A;  1M7E A;  1U5D A;  2DYN A;  3PVL A;  5HE2 A;  1U29 A;  1ISN A;  3KSY A;  1U5F A;  2YS5 A;  3WYF B;  4A6H A;  3GYP A;  1TJ6 A;  2I5C A;  1DRO A;  1PMS A;  1U5G A;  1V89 A;  2DA0 A;  1FHW A;  2K2U A;  2YT0 A;  1MAI A;  3PZD A;  2DHI A;  2UVM A;  5KQ4 A;  1GC6 A;  3QIJ A;  4CHM A;  4HAZ B;  1IRS A;  1J0W A;  3TVV A;  3HW2 B;  4NSW A;  3U7D A;  3QBV B;  4F7H A;  2UZR A;  2DKP A;  2D10 A;  4GN1 A;  2HTH B;  3FSS A;  4P7I A;  3SYX A;  5JLJ B;  2GJY A;  2DX5 A;  4HHV A;  1XR0 B;  2MDX A;  2L1C A;  3ML4 A;  2NMB A;  3SNH A;  2YT1 A;  2DX1 A;  2UZS A;  4WJ7 A;  1GC7 A;  2DTC A;  5D3V A;  3SO6 A;  4GOU A;  1W1H A;  3IVF A;  1XD4 A;  1TXD A;  1RJ2 A;  3PVU A;  4Y94 A;  3UZT A;  1SHC A;  2K2J A;  1UPQ A;  4TKN A;  1XCG A;  3GF9 A;  1MPH A;  2AEH A;  4HAW B;  2Y8G A;  1DBH A;  1WG7 A;  1X86 A;  2LG1 A;  3CXB B;  4KVG B;  1ZC4 B;  1WI1 A;  2DFK A;  5J3Y A;  2I1J A;  2CAY A;  4GZU A;  2VRW B;  2E2X A;  3AU4 A;  5FI1 A;  1EVH A;  1X1G A;  2D9Z A;  3ODX A;  1V5P A;  1QC6 A;  5FI0 A;  5DHA B;  1WJ1 A;  1V5M A;  3HK0 A;  2K00 A;  1FOE A;  4XWX A;  3PEG A;  1DDW A;  2DLW A;  2LOZ A;  4BBK A;  1OMW A;  5JHH A;  4A6F B;  3WA0 A;  3F0W A;  5HE0 A;  1FGY A;  2ROZ B;  5KCV A;  1ZC3 B;  2DKQ A;  4WVF B;  5D27 A;  4EKU A;  4D0O A;  1NU2 A;  2D4Q A;  2AL6 A;  1XOD A;  4B6H A;  3NSU A;  2W2X C;  2YS3 A;  2COC A;  1GG3 A;  3M1I B;  3KRX A;  1FHO A;  4F7U P;  2QKM A;  1WVH A;  5LON B;  5D3X A;  3ZVR A;  1XKE A;  4L6E A;  1V5U A;  5L81 A;  4CYE A;  3KY9 A;  1BWN A;  1LB1 A;  3D8D A;  2COA A;  3MDB C;  2G35 A;  2LKO A;  2MKR A;  1W1G A;  4HB2 B;  3VIA A;  2HE7 A;  1UNR A;  1P6S A;  4D0N B;  1FAO A;  4Z2N A;  1MIZ B;  1ZSQ A;  4KAX B;  1UNP A;  4EMO A;  1X1F A;  5DH9 B;  2NZ8 B;  2OQB A;  3ULB A;  3EO2 A;  2Z0P A;  1DDM A;  3PP2 A;  4K2O A;  2Q13 A;  2Y8F A;  1MK9 B;  1BAK A;  4Z2M B;  3KRW A;  1V61 A;  4MK0 A;  1KI1 B;  1PFJ A;  3HQC A;  2D9W A;  2CRF A;  3AU5 A;  4KHA A;  3V5W A;  4NY0 A;  3TW1 A;  1P5T A;  5HE3 A;  1DYN A;  1OQN A;  2LUL A;  2L2I A;  2RUK B;  4DX9 0;  5C79 A;  3P7Z A;  3DXD A;  3KZ1 A;  5C6R A;  2RVB B;  2W2X D;  1NTV A;  5LOP B;  4KHO A;  3ODO A;  2QKL A;  4IAP A;  2EJ8 A;  1ZM0 A;  5J3T A;  5D3W A;  5GOW B;  5HE1 A;  2RSG A;  4GMX B;  4K2P A;  2YVC A;  1H10 A;  4CHJ A;  3FM8 C;  3FEH A;  5CLQ B;  1K5D B;  4MY6 A;  2PZ1 A;  5CLL B;  1X05 A;  2MWN B;  5EFX A;  2ZPY A;  3JV3 A;  3PG7 A;  3TO1 A;  3PSC A;  2ELB A;  2J0M A;  4ZRK A;  1BTN A;  2CY5 A;  1Y19 B;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1LB1A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations