2NZ8 | Genus

Total Genus 91

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	91
sequence length	305
structure length	279
Chain Sequence	ARRKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFSQGELILQESFQHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFATSDNKIVLKASSIENKQDWIKHIREVIQERT

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 279 atoms

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1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

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279 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Signaling protein,cell cycle
source organism	Homo sapiens
publication title	The DH and PH Domains of Trio Coordinately Engage Rho GTPases for their Efficient Activation pubmed doi rcsb
molecule keywords	ras-related C3 botulinum toxin substrate 1 isoform Rac1
total genus	91
structure length	279
sequence length	305
ec nomenclature	ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date	2006-11-22

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
B	PF00169	PH	PH domain
B	PF00621	RhoGEF	RhoGEF domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.900.10	Mainly Alpha	Up-down Bundle	Dbl Homology Domain; Chain A	Dbl homology (DH) domain	2nz8B01
2.30.29.30	Mainly Beta	Roll	PH-domain like	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	2nz8B02

2I1KA 3AJ4A 4Z2NA 4HDOA 5JHGA 3MDBC 4HAXB 1SGHA 2HTHB 1TXDA 5LOPB 5C5BB 1EVHA 3DXEA 3X23A 4HAVB 4GMXB 5LONB 1LW3A 3OANA 2YS1A 3FSSA 1FHXA 1F5XA 1MK7B 4MK0A 3KSYA 4L6EA 2ROVA 2KUPA 5CLLB 3SV1A 1MK9B 5FI1A 3CIKA 2COFA 2D9XA 1XD4A 5D27A 2RGNB 1M7RA 1UPQA 3TFMA 3ODXA 3ULBA 2QKMA 3VOQA 3PG7A 1K5DB 1LB1A 3HK0A 1UNQA 5KQ1A 2P8VA 2W2WA 1H10A 1BY1A 2Y8FA 2EMSA 2BCJA 2EMTA 1W1DA 4HB4B 2AL6A 3FM8C 1U5DA 4A6HA 2D9WA 1BAKA 1FGYA 5D3XA 1PFJA 2RVBB 2D9YA 2YSZA 2OTXA 1WGQA 1V5UA 2YS3A 2V76A 3PZDA 4KHOA 2I5FA 3MPXA 3P6AA 3F0WA 3KRWA 2DX1A 2YT0A 2Y7BA 3G9WA 3KRXA 4YL8A 1P6SA 1V88A 3DXDA 4PNKA 5GOWB 1U29A 1NI2A 3N7CA 2IYBA 4ZRIA 3VIAA 2AEHA 1XKEA 2NZ8B 1MIZB 1X1GA 1W1GA 4GXBA 2RSGA 3PVWA 2RNRB 4D0NB 2LYDA 4ZRKA 1GC7A 5HE3A 5KCVA 2RUKB 1GG3A 3QIJA 2KGXB 2LKOA 2L1CA 4WVFB 2J0KA 3V5WA 4TYZA 4H8SA 1X11A 4MY6A 3CXBB 1H4RA 4EKUA 1BTKA 1Z87A 4A6FB 3HQCA 2DHKA 4C0AA 1Y19B 2RLOA 2CY5A 3PVLA 2P0FA 3ULCA 5J3QA 1GC6A 3A98B 1DYNA 2D9ZA 2DKQA 1X86A 2DTCA 3D8DA 3EO2A 4K2PA 2ELBA 2LULA 1KZGA 2K2JA 4GZUA 4F7HA 3JV3A 3A8PA 4KAXB 1Y5OA 2H7DA 4KHAA 2GCJA 2W2XC 1U5GA 4HDQA 2MKRA 5C5BA 3GYPA 1DDMA 5DHFB 5D3WA 4HAWB 3PEGA 1DDWA 3ODWA 4GYVA 2E2XA 1TQZA 2YVCA 2G35A 1EAZA 3D8EA 3SNHA 2Q13A 2CAYA 3ODOA 4PQ0A 3SUZA 2UZSA 2VSZA 2HE7A 2I1JA 1RRPB 2DYQA 3TO1A 1MPHA 2Z0QA 3AU4A 2ROZB 2KR9A 2R0DA 3ZVRA 1UNRA 2J0MA 2EC1A 3TVVA 4HAYB 1FB8A 2DA0A 5JHHA 4F7UP 3F5RA 3TW1A 4EMOA 4BBKA 1WGUA 1XR0B 4HB2B 4WJ7A 2YS5A 1U2BA 2CRFA 4DX8A 4XWXA 5C6RA 3PP2A 2COCA 2DKPA 2DYNA 2GCLA 1EGXA 2ADZA 3TCAA 2OQBA 4K17A 3DXCA 1KI1B 3IVFA 1WVHA 1P3RA 2J59M 4DXAB 2KCJA 4HAZB 1WI1A 1XODA 2LOZA 2P0DA 5D3YA 5KQ4A 1RJ2A 2Y8GA 2H7EA 1BWNA 3U7DA 4HB3B 4K2OA 2GS0A 4MT7A 3U8ZA 2LG1A 1J0WA 2R09A 2D9VA 3PVUA 2DN6A 4CYEA 3LJUX 4IAPA 1TJ6A 4KVGB 2UZRA 1B55A 1ZM0A 5HE2A 4Y94A 1PLSA 2D10A 2NMBA 2MFQA 2N23A 4GPTB 1ZSQA 1J19A 1X05A 1U5EA 1AWEA 4ZRJA 2D4QA 2EJ8A 5HE0A 4A6FA 3WYFB 1FHOA 1EF1A 2Z0PA 3QWMA 4GOUA 5FI0A 1ZVRA 3M1IB 2YF0A 4GN1A 1OY2A 4HAUB 2N0YA 4DBBA 4IOYX 2IFSA 1OQNA 2MDXA 3BINA 2DHJA 4D0OA 1K5GB 4F7GA 4KHBB 2VKIA 2UVMA 1WJ1A 1DROA 1N3HA 1Q67A 3GF9A 1ZC3B 4HATB 2M38A 2YRYA 3SYXA 1M7EA 1U27A 2DX5A 4HB0B 1OMWA 4P7IA 1MIXA 1WJMA 3HW2B 1AQCA 2YT1A 2L2IA 1FHWA 2CODA 3O96A 5DHAB 1KZ7A 2QKLA 5DI9B 1SHCA 1DBHA 4TKNA 4A6KA 1X1FA 3RCPA 5JP4A 1WG7A 4CHJA 5CLQB 3FEHA 1I2HA 2COAA 1MKEA 4K81A 2P0HA 1PMSA 2JP2A 3KY9A 4DX90 1ZC4B 1NTVA 2CY4A 1P5TA 3BJIA 1QC6A 2DLWA 1BTNA 2LOXA 3AU5A 3UZTA 4NY0A 1U5FA 3GYOA 4Z2MB 2J0JA 2K00A 2Z0OA 4IFSA 1UNPA 1V89A 1V5PA 3NSUA 1UEFA 2FJLA 1FAOA 1MAIA 3ZDTA 5DH9B 5EFXA 4GMVA 1NU2A 1DDVA 1XX0A 3A8QA 5C16A 4NSWA 1I7AA 2ZPYA 5D3VA 3SO6A 5HE1A 1FOEA 2PZ1A 3P7ZA 2W2XD 2D11A 2VRWB 3ML4A 2MWNB 2M14A 1ISNA 2ELAA 4CHMA 2X18A 5J3TA 5JLJB 1UPRA 1W1HA 3KZ1A 3QBVB 4HHVA 4EJNA 1IRSA 5L81A 1V5MA 2D2QA 4B6HA 1NTYA 3PSCA 1QQGA 3WA0A 5C79A 2K2UA 3T06A 5J3YA 5DIFB 2I5CA 1V61A 4YONA 2DHIA 1E5WA 4WSFA 3D8FA 2XQNM 1XCGA 2GJYA 1FGZA 2DFKA 4A5KA
chains in the Genus database with same CATH superfamily

2I1KA 3AJ4A 4Z2NA 4HDOA 5JHGA 3MDBC 4HAXB 1SGHA 2HTHB 2Z13A 1TXDA 5LOPB 5C5BB 1EVHA 3DXEA 3X23A 4HAVB 4GMXB 5LONB 1LW3A 3OANA 2YS1A 3FSSA 3U12A 1FHXA 1F5XA 1MK7B 4MK0A 3KSYA 4L6EA 2ROVA 2KUPA 4KHBA 5CLLB 3SV1A 1MK9B 5FI1A 3CIKA 2COFA 2D9XA 1XD4A 5D27A 2RGNB 1M7RA 1UPQA 3TFMA 3ODXA 3ULBA 2QKMA 3VOQA 3PG7A 1K5DB 2ZKMX 1LB1A 3HK0A 1UNQA 4QJ3B 5KQ1A 2P8VA 2W2WA 1H10A 1BY1A 2Y8FA 2EMSA 3NWFA 4L1RA 2BCJA 2EMTA 1W1DA 4HB4B 2AL6A 2Z59A 3FM8C 1U5DA 4A6HA 2D9WA 4CSQA 1BAKA 1FGYA 5D3XA 1PFJA 2RVBB 2D9YA 2YSZA 2OTXA 1WGQA 1V5UA 2YS3A 5IRSA 2V76A 3PZDA 4KHOA 2I5FA 3MPXA 3P6AA 3F0WA 3KRWA 2DX1A 2YT0A 2Y7BA 3G9WA 3KRXA 4YL8A 1P6SA 1V88A 3DXDA 4PNKA 5GOWB 1U29A 1NI2A 3N7CA 3NW8A 2IYBA 4ZRIA 3VIAA 2AEHA 1XKEA 2NZ8B 1MIZB 1X1GA 1W1GA 4GXBA 2RSGA 3PVWA 2RNRB 4D0NB 2LYDA 4ZRKA 1GC7A 5HE3A 5KCVA 2YT2A 2RUKB 1GG3A 3QIJA 2KGXB 2LKOA 2L1CA 4WVFB 2J0KA 3V5WA 4TYZA 4H8SA 1X11A 4MY6A 3CXBB 1H4RA 4D6WA 5I2SA 4EKUA 1BTKA 1Z87A 4A6FB 3HQCA 2DHKA 4C0AA 1Y19B 2RLOA 5I2MA 2CY5A 3PVLA 2P0FA 3ULCA 5J3QA 1GC6A 3A98B 1DYNA 2D9ZA 2DKQA 1X86A 2K49A 2DTCA 3D8DA 3EO2A 4K2PA 2ELBA 2LULA 1KZGA 2K2JA 4GZUA 4F7HA 3JV3A 3A8PA 4KAXB 3NWAA 1Y5OA 2H7DA 4KHAA 2GCJA 2W2XC 3HSAA 1U5GA 4HDQA 2MKRA 5C5BA 1MI1A 4GNKB 3GYPA 1DDMA 5DHFB 5D3WA 4HAWB 3PEGA 1DDWA 3ODWA 4GYVA 2E2XA 2K8EA 1TQZA 2YVCA 2G35A 1EAZA 3D8EA 3SNHA 3HIEA 2Q13A 2CAYA 3ODOA 4DIXA 4PQ0A 3SUZA 2UZSA 2VSZA 2HE7A 2I1JA 1RRPB 2DYQA 3TO1A 1MPHA 2Z0QA 3AU4A 2ROZB 2KR9A 1T77A 2R0DA 3ZVRA 1UNRA 2J0MA 2EC1A 4HSIA 3TVVA 4HAYB 1FB8A 2DA0A 5JHHA 4F7UP 3F5RA 3TW1A 4EMOA 4BBKA 1WGUA 1XR0B 4HB2B 4WJ7A 2YS5A 1U2BA 2CRFA 4DX8A 2R2YA 3NWDA 4XWXA 3A58A 5C6RA 3PP2A 2COCA 2DKPA 2DYNA 2GCLA 3DCXA 1EGXA 2ADZA 2KIGA 3TCAA 2OQBA 4K17A 3DXCA 1KI1B 3IVFA 1WVHA 1P3RA 2J59M 4DXAB 2KCJA 4HAZB 1WI1A 1XODA 4OSNA 2LOZA 2P0DA 5D3YA 5KQ4A 1RJ2A 2Y8GA 2H7EA 1BWNA 3U7DA 4HB3B 4K2OA 2GS0A 4MT7A 3U8ZA 2LG1A 1J0WA 2R09A 2D9VA 3PVUA 2DN6A 4CYEA 3LJUX 4IAPA 1TJ6A 4KVGB 2UZRA 1B55A 1ZM0A 5HE2A 4Y94A 1PLSA 2D10A 2NMBA 2MFQA 2N23A 4GPTB 1ZSQA 4QJ5B 5LG4B 1J19A 1X05A 1U5EA 1AWEA 4ZRJA 2D4QA 2EJ8A 5HE0A 4A6FA 3WYFB 1FHOA 1EF1A 2Z0PA 3QWMA 2RRFA 4GOUA 5FI0A 1ZVRA 3M1IB 2YF0A 4GN1A 1OY2A 1ZYIA 4HAUB 2N0YA 4DBBA 4IOYX 2IFSA 1OQNA 2MDXA 3BINA 2DHJA 4D0OA 1K5GB 4F7GA 5M4YB 4KHBB 2VKIA 2UVMA 1WJ1A 1DROA 1N3HA 1Q67A 3GF9A 1ZC3B 4HATB 2M38A 2YRYA 3SYXA 1M7EA 1U27A 2DX5A 4HB0B 1OMWA 4P7IA 1MIXA 2KR0A 1WJMA 3HW2B 1AQCA 2YT1A 2L2IA 4QJ4B 2GUMA 1FHWA 2CODA 3O96A 5DHAB 1KZ7A 2Z4DA 2QKLA 5DI9B 1SHCA 1DBHA 4TKNA 4A6KA 1X1FA 3FVCA 3RCPA 5JP4A 2KUQA 1WG7A 4CHJA 5CLQB 3FEHA 1I2HA 2COAA 1MKEA 4K81A 2P0HA 2FJUB 1PMSA 2JP2A 3KY9A 4OT1A 4DX90 1ZC4B 1NTVA 2CY4A 1P5TA 3BJIA 1QC6A 2DLWA 1BTNA 2LOXA 3AU5A 3UZTA 4NY0A 1U5FA 3GYOA 4Z2MB 2J0JA 2K00A 2Z0OA 4IFSA 1UNPA 1V89A 2NBVA 1V5PA 3OHMB 3NSUA 1UEFA 3B77A 2FJLA 1FAOA 1MAIA 3ZDTA 5DH9B 5EFXA 4GMVA 1NU2A 1DDVA 1XX0A 3A8QA 5C16A 4NSWA 1I7AA 2ZPYA 5D3VA 3SO6A 5HE1A 1FOEA 2PZ1A 3P7ZA 2W2XD 2D11A 2VRWB 3ML4A 2MWNB 2M14A 1ISNA 2ELAA 4CHMA 2X18A 5J3TA 5JLJB 1UPRA 1W1HA 3KZ1A 3QBVB 4HHVA 4EJNA 1IRSA 5L81A 1V5MA 2D2QA 2KIEA 4B6HA 1NTYA 3PSCA 1QQGA 3WA0A 5C79A 2K2UA 3T06A 5J3YA 5DIFB 2I5CA 1V61A 4YONA 2DHIA 1E5WA 4WSFA 3D8FA 2XQNM 1XCGA 2GJYA 1FGZA 4QXAB 2DFKA 4A5KA 2Z14A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2I1K A;  3AJ4 A;  4Z2N A;  4HDO A;  5JHG A;  3MDB C;  4HAX B;  1SGH A;  2HTH B;  1TXD A;  5LOP B;  5C5B B;  1EVH A;  3DXE A;  3X23 A;  4HAV B;  4GMX B;  5LON B;  1LW3 A;  3OAN A;  2YS1 A;  3FSS A;  1FHX A;  1F5X A;  1MK7 B;  4MK0 A;  3KSY A;  4L6E A;  2ROV A;  2KUP A;  5CLL B;  3SV1 A;  1MK9 B;  5FI1 A;  3CIK A;  2COF A;  2D9X A;  1XD4 A;  5D27 A;  2RGN B;  1M7R A;  1UPQ A;  3TFM A;  3ODX A;  3ULB A;  2QKM A;  3VOQ A;  3PG7 A;  1K5D B;  1LB1 A;  3HK0 A;  1UNQ A;  5KQ1 A;  2P8V A;  2W2W A;  1H10 A;  1BY1 A;  2Y8F A;  2EMS A;  2BCJ A;  2EMT A;  1W1D A;  4HB4 B;  2AL6 A;  3FM8 C;  1U5D A;  4A6H A;  2D9W A;  1BAK A;  1FGY A;  5D3X A;  1PFJ A;  2RVB B;  2D9Y A;  2YSZ A;  2OTX A;  1WGQ A;  1V5U A;  2YS3 A;  2V76 A;  3PZD A;  4KHO A;  2I5F A;  3MPX A;  3P6A A;  3F0W A;  3KRW A;  2DX1 A;  2YT0 A;  2Y7B A;  3G9W A;  3KRX A;  4YL8 A;  1P6S A;  1V88 A;  3DXD A;  4PNK A;  5GOW B;  1U29 A;  1NI2 A;  3N7C A;  2IYB A;  4ZRI A;  3VIA A;  2AEH A;  1XKE A;  2NZ8 B;  1MIZ B;  1X1G A;  1W1G A;  4GXB A;  2RSG A;  3PVW A;  2RNR B;  4D0N B;  2LYD A;  4ZRK A;  1GC7 A;  5HE3 A;  5KCV A;  2RUK B;  1GG3 A;  3QIJ A;  2KGX B;  2LKO A;  2L1C A;  4WVF B;  2J0K A;  3V5W A;  4TYZ A;  4H8S A;  1X11 A;  4MY6 A;  3CXB B;  1H4R A;  4EKU A;  1BTK A;  1Z87 A;  4A6F B;  3HQC A;  2DHK A;  4C0A A;  1Y19 B;  2RLO A;  2CY5 A;  3PVL A;  2P0F A;  3ULC A;  5J3Q A;  1GC6 A;  3A98 B;  1DYN A;  2D9Z A;  2DKQ A;  1X86 A;  2DTC A;  3D8D A;  3EO2 A;  4K2P A;  2ELB A;  2LUL A;  1KZG A;  2K2J A;  4GZU A;  4F7H A;  3JV3 A;  3A8P A;  4KAX B;  1Y5O A;  2H7D A;  4KHA A;  2GCJ A;  2W2X C;  1U5G A;  4HDQ A;  2MKR A;  5C5B A;  3GYP A;  1DDM A;  5DHF B;  5D3W A;  4HAW B;  3PEG A;  1DDW A;  3ODW A;  4GYV A;  2E2X A;  1TQZ A;  2YVC A;  2G35 A;  1EAZ A;  3D8E A;  3SNH A;  2Q13 A;  2CAY A;  3ODO A;  4PQ0 A;  3SUZ A;  2UZS A;  2VSZ A;  2HE7 A;  2I1J A;  1RRP B;  2DYQ A;  3TO1 A;  1MPH A;  2Z0Q A;  3AU4 A;  2ROZ B;  2KR9 A;  2R0D A;  3ZVR A;  1UNR A;  2J0M A;  2EC1 A;  3TVV A;  4HAY B;  1FB8 A;  2DA0 A;  5JHH A;  4F7U P;  3F5R A;  3TW1 A;  4EMO A;  4BBK A;  1WGU A;  1XR0 B;  4HB2 B;  4WJ7 A;  2YS5 A;  1U2B A;  2CRF A;  4DX8 A;  4XWX A;  5C6R A;  3PP2 A;  2COC A;  2DKP A;  2DYN A;  2GCL A;  1EGX A;  2ADZ A;  3TCA A;  2OQB A;  4K17 A;  3DXC A;  1KI1 B;  3IVF A;  1WVH A;  1P3R A;  2J59 M;  4DXA B;  2KCJ A;  4HAZ B;  1WI1 A;  1XOD A;  2LOZ A;  2P0D A;  5D3Y A;  5KQ4 A;  1RJ2 A;  2Y8G A;  2H7E A;  1BWN A;  3U7D A;  4HB3 B;  4K2O A;  2GS0 A;  4MT7 A;  3U8Z A;  2LG1 A;  1J0W A;  2R09 A;  2D9V A;  3PVU A;  2DN6 A;  4CYE A;  3LJU X;  4IAP A;  1TJ6 A;  4KVG B;  2UZR A;  1B55 A;  1ZM0 A;  5HE2 A;  4Y94 A;  1PLS A;  2D10 A;  2NMB A;  2MFQ A;  2N23 A;  4GPT B;  1ZSQ A;  1J19 A;  1X05 A;  1U5E A;  1AWE A;  4ZRJ A;  2D4Q A;  2EJ8 A;  5HE0 A;  4A6F A;  3WYF B;  1FHO A;  1EF1 A;  2Z0P A;  3QWM A;  4GOU A;  5FI0 A;  1ZVR A;  3M1I B;  2YF0 A;  4GN1 A;  1OY2 A;  4HAU B;  2N0Y A;  4DBB A;  4IOY X;  2IFS A;  1OQN A;  2MDX A;  3BIN A;  2DHJ A;  4D0O A;  1K5G B;  4F7G A;  4KHB B;  2VKI A;  2UVM A;  1WJ1 A;  1DRO A;  1N3H A;  1Q67 A;  3GF9 A;  1ZC3 B;  4HAT B;  2M38 A;  2YRY A;  3SYX A;  1M7E A;  1U27 A;  2DX5 A;  4HB0 B;  1OMW A;  4P7I A;  1MIX A;  1WJM A;  3HW2 B;  1AQC A;  2YT1 A;  2L2I A;  1FHW A;  2COD A;  3O96 A;  5DHA B;  1KZ7 A;  2QKL A;  5DI9 B;  1SHC A;  1DBH A;  4TKN A;  4A6K A;  1X1F A;  3RCP A;  5JP4 A;  1WG7 A;  4CHJ A;  5CLQ B;  3FEH A;  1I2H A;  2COA A;  1MKE A;  4K81 A;  2P0H A;  1PMS A;  2JP2 A;  3KY9 A;  4DX9 0;  1ZC4 B;  1NTV A;  2CY4 A;  1P5T A;  3BJI A;  1QC6 A;  2DLW A;  1BTN A;  2LOX A;  3AU5 A;  3UZT A;  4NY0 A;  1U5F A;  3GYO A;  4Z2M B;  2J0J A;  2K00 A;  2Z0O A;  4IFS A;  1UNP A;  1V89 A;  1V5P A;  3NSU A;  1UEF A;  2FJL A;  1FAO A;  1MAI A;  3ZDT A;  5DH9 B;  5EFX A;  4GMV A;  1NU2 A;  1DDV A;  1XX0 A;  3A8Q A;  5C16 A;  4NSW A;  1I7A A;  2ZPY A;  5D3V A;  3SO6 A;  5HE1 A;  1FOE A;  2PZ1 A;  3P7Z A;  2W2X D;  2D11 A;  2VRW B;  3ML4 A;  2MWN B;  2M14 A;  1ISN A;  2ELA A;  4CHM A;  2X18 A;  5J3T A;  5JLJ B;  1UPR A;  1W1H A;  3KZ1 A;  3QBV B;  4HHV A;  4EJN A;  1IRS A;  5L81 A;  1V5M A;  2D2Q A;  4B6H A;  1NTY A;  3PSC A;  1QQG A;  3WA0 A;  5C79 A;  2K2U A;  3T06 A;  5J3Y A;  5DIF B;  2I5C A;  1V61 A;  4YON A;  2DHI A;  1E5W A;  4WSF A;  3D8F A;  2XQN M;  1XCG A;  2GJY A;  1FGZ A;  2DFK A;  4A5K A; 
#chains in the Genus database with same CATH topology
 2I1K A;  3AJ4 A;  4Z2N A;  4HDO A;  5JHG A;  3MDB C;  4HAX B;  1SGH A;  2HTH B;  2Z13 A;  1TXD A;  5LOP B;  5C5B B;  1EVH A;  3DXE A;  3X23 A;  4HAV B;  4GMX B;  5LON B;  1LW3 A;  3OAN A;  2YS1 A;  3FSS A;  3U12 A;  1FHX A;  1F5X A;  1MK7 B;  4MK0 A;  3KSY A;  4L6E A;  2ROV A;  2KUP A;  4KHB A;  5CLL B;  3SV1 A;  1MK9 B;  5FI1 A;  3CIK A;  2COF A;  2D9X A;  1XD4 A;  5D27 A;  2RGN B;  1M7R A;  1UPQ A;  3TFM A;  3ODX A;  3ULB A;  2QKM A;  3VOQ A;  3PG7 A;  1K5D B;  2ZKM X;  1LB1 A;  3HK0 A;  1UNQ A;  4QJ3 B;  5KQ1 A;  2P8V A;  2W2W A;  1H10 A;  1BY1 A;  2Y8F A;  2EMS A;  3NWF A;  4L1R A;  2BCJ A;  2EMT A;  1W1D A;  4HB4 B;  2AL6 A;  2Z59 A;  3FM8 C;  1U5D A;  4A6H A;  2D9W A;  4CSQ A;  1BAK A;  1FGY A;  5D3X A;  1PFJ A;  2RVB B;  2D9Y A;  2YSZ A;  2OTX A;  1WGQ A;  1V5U A;  2YS3 A;  5IRS A;  2V76 A;  3PZD A;  4KHO A;  2I5F A;  3MPX A;  3P6A A;  3F0W A;  3KRW A;  2DX1 A;  2YT0 A;  2Y7B A;  3G9W A;  3KRX A;  4YL8 A;  1P6S A;  1V88 A;  3DXD A;  4PNK A;  5GOW B;  1U29 A;  1NI2 A;  3N7C A;  3NW8 A;  2IYB A;  4ZRI A;  3VIA A;  2AEH A;  1XKE A;  2NZ8 B;  1MIZ B;  1X1G A;  1W1G A;  4GXB A;  2RSG A;  3PVW A;  2RNR B;  4D0N B;  2LYD A;  4ZRK A;  1GC7 A;  5HE3 A;  5KCV A;  2YT2 A;  2RUK B;  1GG3 A;  3QIJ A;  2KGX B;  2LKO A;  2L1C A;  4WVF B;  2J0K A;  3V5W A;  4TYZ A;  4H8S A;  1X11 A;  4MY6 A;  3CXB B;  1H4R A;  4D6W A;  5I2S A;  4EKU A;  1BTK A;  1Z87 A;  4A6F B;  3HQC A;  2DHK A;  4C0A A;  1Y19 B;  2RLO A;  5I2M A;  2CY5 A;  3PVL A;  2P0F A;  3ULC A;  5J3Q A;  1GC6 A;  3A98 B;  1DYN A;  2D9Z A;  2DKQ A;  1X86 A;  2K49 A;  2DTC A;  3D8D A;  3EO2 A;  4K2P A;  2ELB A;  2LUL A;  1KZG A;  2K2J A;  4GZU A;  4F7H A;  3JV3 A;  3A8P A;  4KAX B;  3NWA A;  1Y5O A;  2H7D A;  4KHA A;  2GCJ A;  2W2X C;  3HSA A;  1U5G A;  4HDQ A;  2MKR A;  5C5B A;  1MI1 A;  4GNK B;  3GYP A;  1DDM A;  5DHF B;  5D3W A;  4HAW B;  3PEG A;  1DDW A;  3ODW A;  4GYV A;  2E2X A;  2K8E A;  1TQZ A;  2YVC A;  2G35 A;  1EAZ A;  3D8E A;  3SNH A;  3HIE A;  2Q13 A;  2CAY A;  3ODO A;  4DIX A;  4PQ0 A;  3SUZ A;  2UZS A;  2VSZ A;  2HE7 A;  2I1J A;  1RRP B;  2DYQ A;  3TO1 A;  1MPH A;  2Z0Q A;  3AU4 A;  2ROZ B;  2KR9 A;  1T77 A;  2R0D A;  3ZVR A;  1UNR A;  2J0M A;  2EC1 A;  4HSI A;  3TVV A;  4HAY B;  1FB8 A;  2DA0 A;  5JHH A;  4F7U P;  3F5R A;  3TW1 A;  4EMO A;  4BBK A;  1WGU A;  1XR0 B;  4HB2 B;  4WJ7 A;  2YS5 A;  1U2B A;  2CRF A;  4DX8 A;  2R2Y A;  3NWD A;  4XWX A;  3A58 A;  5C6R A;  3PP2 A;  2COC A;  2DKP A;  2DYN A;  2GCL A;  3DCX A;  1EGX A;  2ADZ A;  2KIG A;  3TCA A;  2OQB A;  4K17 A;  3DXC A;  1KI1 B;  3IVF A;  1WVH A;  1P3R A;  2J59 M;  4DXA B;  2KCJ A;  4HAZ B;  1WI1 A;  1XOD A;  4OSN A;  2LOZ A;  2P0D A;  5D3Y A;  5KQ4 A;  1RJ2 A;  2Y8G A;  2H7E A;  1BWN A;  3U7D A;  4HB3 B;  4K2O A;  2GS0 A;  4MT7 A;  3U8Z A;  2LG1 A;  1J0W A;  2R09 A;  2D9V A;  3PVU A;  2DN6 A;  4CYE A;  3LJU X;  4IAP A;  1TJ6 A;  4KVG B;  2UZR A;  1B55 A;  1ZM0 A;  5HE2 A;  4Y94 A;  1PLS A;  2D10 A;  2NMB A;  2MFQ A;  2N23 A;  4GPT B;  1ZSQ A;  4QJ5 B;  5LG4 B;  1J19 A;  1X05 A;  1U5E A;  1AWE A;  4ZRJ A;  2D4Q A;  2EJ8 A;  5HE0 A;  4A6F A;  3WYF B;  1FHO A;  1EF1 A;  2Z0P A;  3QWM A;  2RRF A;  4GOU A;  5FI0 A;  1ZVR A;  3M1I B;  2YF0 A;  4GN1 A;  1OY2 A;  1ZYI A;  4HAU B;  2N0Y A;  4DBB A;  4IOY X;  2IFS A;  1OQN A;  2MDX A;  3BIN A;  2DHJ A;  4D0O A;  1K5G B;  4F7G A;  5M4Y B;  4KHB B;  2VKI A;  2UVM A;  1WJ1 A;  1DRO A;  1N3H A;  1Q67 A;  3GF9 A;  1ZC3 B;  4HAT B;  2M38 A;  2YRY A;  3SYX A;  1M7E A;  1U27 A;  2DX5 A;  4HB0 B;  1OMW A;  4P7I A;  1MIX A;  2KR0 A;  1WJM A;  3HW2 B;  1AQC A;  2YT1 A;  2L2I A;  4QJ4 B;  2GUM A;  1FHW A;  2COD A;  3O96 A;  5DHA B;  1KZ7 A;  2Z4D A;  2QKL A;  5DI9 B;  1SHC A;  1DBH A;  4TKN A;  4A6K A;  1X1F A;  3FVC A;  3RCP A;  5JP4 A;  2KUQ A;  1WG7 A;  4CHJ A;  5CLQ B;  3FEH A;  1I2H A;  2COA A;  1MKE A;  4K81 A;  2P0H A;  2FJU B;  1PMS A;  2JP2 A;  3KY9 A;  4OT1 A;  4DX9 0;  1ZC4 B;  1NTV A;  2CY4 A;  1P5T A;  3BJI A;  1QC6 A;  2DLW A;  1BTN A;  2LOX A;  3AU5 A;  3UZT A;  4NY0 A;  1U5F A;  3GYO A;  4Z2M B;  2J0J A;  2K00 A;  2Z0O A;  4IFS A;  1UNP A;  1V89 A;  2NBV A;  1V5P A;  3OHM B;  3NSU A;  1UEF A;  3B77 A;  2FJL A;  1FAO A;  1MAI A;  3ZDT A;  5DH9 B;  5EFX A;  4GMV A;  1NU2 A;  1DDV A;  1XX0 A;  3A8Q A;  5C16 A;  4NSW A;  1I7A A;  2ZPY A;  5D3V A;  3SO6 A;  5HE1 A;  1FOE A;  2PZ1 A;  3P7Z A;  2W2X D;  2D11 A;  2VRW B;  3ML4 A;  2MWN B;  2M14 A;  1ISN A;  2ELA A;  4CHM A;  2X18 A;  5J3T A;  5JLJ B;  1UPR A;  1W1H A;  3KZ1 A;  3QBV B;  4HHV A;  4EJN A;  1IRS A;  5L81 A;  1V5M A;  2D2Q A;  2KIE A;  4B6H A;  1NTY A;  3PSC A;  1QQG A;  3WA0 A;  5C79 A;  2K2U A;  3T06 A;  5J3Y A;  5DIF B;  2I5C A;  1V61 A;  4YON A;  2DHI A;  1E5W A;  4WSF A;  3D8F A;  2XQN M;  1XCG A;  2GJY A;  1FGZ A;  4QXA B;  2DFK A;  4A5K A;  2Z14 A; 
#chains in the Genus database with same CATH homology
 2I1K A;  3AJ4 A;  4Z2N A;  4HDO A;  5JHG A;  3MDB C;  4HAX B;  1SGH A;  2HTH B;  1TXD A;  5LOP B;  5C5B B;  1EVH A;  3DXE A;  3X23 A;  4HAV B;  4GMX B;  5LON B;  1LW3 A;  3OAN A;  2YS1 A;  3FSS A;  1FHX A;  1F5X A;  1MK7 B;  4MK0 A;  3KSY A;  4L6E A;  2ROV A;  2KUP A;  5CLL B;  3SV1 A;  1MK9 B;  5FI1 A;  3CIK A;  2COF A;  2D9X A;  1XD4 A;  5D27 A;  2RGN B;  1M7R A;  1UPQ A;  3TFM A;  3ODX A;  3ULB A;  2QKM A;  3VOQ A;  3PG7 A;  1K5D B;  1LB1 A;  3HK0 A;  1UNQ A;  5KQ1 A;  2P8V A;  2W2W A;  1H10 A;  1BY1 A;  2Y8F A;  2EMS A;  2BCJ A;  2EMT A;  1W1D A;  4HB4 B;  2AL6 A;  3FM8 C;  1U5D A;  4A6H A;  2D9W A;  1BAK A;  1FGY A;  5D3X A;  1PFJ A;  2RVB B;  2D9Y A;  2YSZ A;  2OTX A;  1WGQ A;  1V5U A;  2YS3 A;  2V76 A;  3PZD A;  4KHO A;  2I5F A;  3MPX A;  3P6A A;  3F0W A;  3KRW A;  2DX1 A;  2YT0 A;  2Y7B A;  3G9W A;  3KRX A;  4YL8 A;  1P6S A;  1V88 A;  3DXD A;  4PNK A;  5GOW B;  1U29 A;  1NI2 A;  3N7C A;  2IYB A;  4ZRI A;  3VIA A;  2AEH A;  1XKE A;  2NZ8 B;  1MIZ B;  1X1G A;  1W1G A;  4GXB A;  2RSG A;  3PVW A;  2RNR B;  4D0N B;  2LYD A;  4ZRK A;  1GC7 A;  5HE3 A;  5KCV A;  2RUK B;  1GG3 A;  3QIJ A;  2KGX B;  2LKO A;  2L1C A;  4WVF B;  2J0K A;  3V5W A;  4TYZ A;  4H8S A;  1X11 A;  4MY6 A;  3CXB B;  1H4R A;  4EKU A;  1BTK A;  1Z87 A;  4A6F B;  3HQC A;  2DHK A;  4C0A A;  1Y19 B;  2RLO A;  2CY5 A;  3PVL A;  2P0F A;  3ULC A;  5J3Q A;  1GC6 A;  3A98 B;  1DYN A;  2D9Z A;  2DKQ A;  1X86 A;  2DTC A;  3D8D A;  3EO2 A;  4K2P A;  2ELB A;  2LUL A;  1KZG A;  2K2J A;  4GZU A;  4F7H A;  3JV3 A;  3A8P A;  4KAX B;  1Y5O A;  2H7D A;  4KHA A;  2GCJ A;  2W2X C;  1U5G A;  4HDQ A;  2MKR A;  5C5B A;  3GYP A;  1DDM A;  5DHF B;  5D3W A;  4HAW B;  3PEG A;  1DDW A;  3ODW A;  4GYV A;  2E2X A;  1TQZ A;  2YVC A;  2G35 A;  1EAZ A;  3D8E A;  3SNH A;  2Q13 A;  2CAY A;  3ODO A;  4PQ0 A;  3SUZ A;  2UZS A;  2VSZ A;  2HE7 A;  2I1J A;  1RRP B;  2DYQ A;  3TO1 A;  1MPH A;  2Z0Q A;  3AU4 A;  2ROZ B;  2KR9 A;  2R0D A;  3ZVR A;  1UNR A;  2J0M A;  2EC1 A;  3TVV A;  4HAY B;  1FB8 A;  2DA0 A;  5JHH A;  4F7U P;  3F5R A;  3TW1 A;  4EMO A;  4BBK A;  1WGU A;  1XR0 B;  4HB2 B;  4WJ7 A;  2YS5 A;  1U2B A;  2CRF A;  4DX8 A;  4XWX A;  5C6R A;  3PP2 A;  2COC A;  2DKP A;  2DYN A;  2GCL A;  1EGX A;  2ADZ A;  3TCA A;  2OQB A;  4K17 A;  3DXC A;  1KI1 B;  3IVF A;  1WVH A;  1P3R A;  2J59 M;  4DXA B;  2KCJ A;  4HAZ B;  1WI1 A;  1XOD A;  2LOZ A;  2P0D A;  5D3Y A;  5KQ4 A;  1RJ2 A;  2Y8G A;  2H7E A;  1BWN A;  3U7D A;  4HB3 B;  4K2O A;  2GS0 A;  4MT7 A;  3U8Z A;  2LG1 A;  1J0W A;  2R09 A;  2D9V A;  3PVU A;  2DN6 A;  4CYE A;  3LJU X;  4IAP A;  1TJ6 A;  4KVG B;  2UZR A;  1B55 A;  1ZM0 A;  5HE2 A;  4Y94 A;  1PLS A;  2D10 A;  2NMB A;  2MFQ A;  2N23 A;  4GPT B;  1ZSQ A;  1J19 A;  1X05 A;  1U5E A;  1AWE A;  4ZRJ A;  2D4Q A;  2EJ8 A;  5HE0 A;  4A6F A;  3WYF B;  1FHO A;  1EF1 A;  2Z0P A;  3QWM A;  4GOU A;  5FI0 A;  1ZVR A;  3M1I B;  2YF0 A;  4GN1 A;  1OY2 A;  4HAU B;  2N0Y A;  4DBB A;  4IOY X;  2IFS A;  1OQN A;  2MDX A;  3BIN A;  2DHJ A;  4D0O A;  1K5G B;  4F7G A;  4KHB B;  2VKI A;  2UVM A;  1WJ1 A;  1DRO A;  1N3H A;  1Q67 A;  3GF9 A;  1ZC3 B;  4HAT B;  2M38 A;  2YRY A;  3SYX A;  1M7E A;  1U27 A;  2DX5 A;  4HB0 B;  1OMW A;  4P7I A;  1MIX A;  1WJM A;  3HW2 B;  1AQC A;  2YT1 A;  2L2I A;  1FHW A;  2COD A;  3O96 A;  5DHA B;  1KZ7 A;  2QKL A;  5DI9 B;  1SHC A;  1DBH A;  4TKN A;  4A6K A;  1X1F A;  3RCP A;  5JP4 A;  1WG7 A;  4CHJ A;  5CLQ B;  3FEH A;  1I2H A;  2COA A;  1MKE A;  4K81 A;  2P0H A;  1PMS A;  2JP2 A;  3KY9 A;  4DX9 0;  1ZC4 B;  1NTV A;  2CY4 A;  1P5T A;  3BJI A;  1QC6 A;  2DLW A;  1BTN A;  2LOX A;  3AU5 A;  3UZT A;  4NY0 A;  1U5F A;  3GYO A;  4Z2M B;  2J0J A;  2K00 A;  2Z0O A;  4IFS A;  1UNP A;  1V89 A;  1V5P A;  3NSU A;  1UEF A;  2FJL A;  1FAO A;  1MAI A;  3ZDT A;  5DH9 B;  5EFX A;  4GMV A;  1NU2 A;  1DDV A;  1XX0 A;  3A8Q A;  5C16 A;  4NSW A;  1I7A A;  2ZPY A;  5D3V A;  3SO6 A;  5HE1 A;  1FOE A;  2PZ1 A;  3P7Z A;  2W2X D;  2D11 A;  2VRW B;  3ML4 A;  2MWN B;  2M14 A;  1ISN A;  2ELA A;  4CHM A;  2X18 A;  5J3T A;  5JLJ B;  1UPR A;  1W1H A;  3KZ1 A;  3QBV B;  4HHV A;  4EJN A;  1IRS A;  5L81 A;  1V5M A;  2D2Q A;  4B6H A;  1NTY A;  3PSC A;  1QQG A;  3WA0 A;  5C79 A;  2K2U A;  3T06 A;  5J3Y A;  5DIF B;  2I5C A;  1V61 A;  4YON A;  2DHI A;  1E5W A;  4WSF A;  3D8F A;  2XQN M;  1XCG A;  2GJY A;  1FGZ A;  2DFK A;  4A5K A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2NZ8B

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations