3T06 | Genus

Total Genus 122

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	122
sequence length	368
structure length	355
Chain Sequence	QNWQHTVGKDVVAGLTQREIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKENLMPREELARLFPNLPELIEIHNSWCEAMKKLREEGPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIALELIKTKQRKESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLESIIKHTEGGTSEHEKLCRARDQCREILKYVNEAVKQTENRHRLEGYQKRLDATALERASNPLAAEFKSLDLTTRKMIHEGPLTWRISKDKTLDLHVLLLEDLLVLLQKQDEKLLLKCTFSPVLKLNAVLIRSVATDKRAFFIICTSKLGPPQIYELVALTSSDKNTWMELLEEAVRNA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__562508796025888__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__562508796025888__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/3T06/A/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__562508796025888__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"562508796025888","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/3T06/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__562508796025888__ ready

script 1 started

platformSpeed = 8

Viewer cachePut cache://localLOAD_/file/5d00038f3ab827ed313ccf32/pdb.gz

Viewer cachePut https://genus.fuw.edu.pl/file/5d00038f3ab827ed313ccf32/pdb.gz

FileManager.getAtomSetCollectionFromFile(/file/5d00038f3ab827ed313ccf32/pdb.gz)

loadScript /static/js/j2s/core/corezip.z.js

The Resolver thinks Pdb

loadScript /static/js/j2s/core/corebio.z.js

Time for openFile(/file/5d00038f3ab827ed313ccf32/pdb.gz): 338 ms

reading 355 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

355 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 26 ms

Adding embedded #jmolscript: select ({0:354});backbone only;select *;

platformSpeed = 8

cartoonsFancy = true

sheetSmoothing = 1.0

traceAlpha = true

loadScript /static/js/j2s/core/corescriptcmd.z.js

specularPower = 9

ambientPercent = 20

antialiasDisplay = true

Script completed

Jmol script terminated

loadScript /static/js/j2s/J/g3d/HermiteRenderer.js

loadScript /static/js/j2s/J/renderbio/BioMeshRenderer.js

loadScript /static/js/j2s/J/render/MeshRenderer.js

loadScript /static/js/j2s/J/shape/Mesh.js

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Signaling protein
source organism	Homo sapiens
publication title	Insights into the Molecular Activation Mechanism of the RhoA-specific Guanine Nucleotide Exchange Factor, PDZRhoGEF. pubmed doi rcsb
molecule keywords	Rho guanine nucleotide exchange factor 11
total genus	122
structure length	355
sequence length	368
chains with identical sequence	E
ec nomenclature
pdb deposition date	2011-07-19

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00621	RhoGEF	RhoGEF domain
A	PF17838	PH_16	PH domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.900.10	Mainly Alpha	Up-down Bundle	Dbl Homology Domain; Chain A	Dbl homology (DH) domain	3t06A01
2.30.29.30	Mainly Beta	Roll	PH-domain like	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	3t06A02

4HDOA 1LB1A 3A98B 1BWNA 2I1JA 1LW3A 1WGUA 2RUKB 3D8EA 2D9XA 1FB8A 4PQ0A 1NI2A 1WJ1A 2DKPA 4ZRJA 5C79A 3HK0A 3G9WA 5FI0A 5C6RA 4NY0A 2COAA 4IAPA 4GN1A 1WJMA 2I5FA 1V88A 4CHJA 3SV1A 1V61A 3DXEA 1QQGA 2BCJA 1U27A 2DYNA 4Z2NA 2MFQA 4DBBA 1E5WA 4DXAB 4D0OA 4CHMA 4GZUA 2COCA 2DHJA 4A6KA 2DHIA 2QKMA 4HAUB 3TCAA 3AU5A 1XD4A 4NSWA 4DX90 1SHCA 2LKOA 3FEHA 1NTVA 4A5KA 3QBVB 3IVFA 3BINA 4YL8A 2Y8GA 2VKIA 3PEGA 3ODOA 1Z87A 4ZRIA 2DTCA 3V5WA 2KR9A 2IYBA 1UPQA 1J19A 1EF1A 2KCJA 2ELAA 5JLJB 4GXBA 1I2HA 2JP2A 3ZVRA 1UEFA 1ZVRA 4HB4B 1P5TA 3KZ1A 3D8FA 1U5DA 4K2OA 2J0JA 1WG7A 1KI1B 4A6FA 1ZC3B 5C5BB 4HAXB 2CAYA 5DHFB 1XR0B 1K5GB 2DX1A 3SUZA 3GYOA 3QWMA 2KUPA 4GPTB 3QIJA 2COFA 2Y7BA 5DIFB 2YT0A 4K81A 4PNKA 5HE2A 4KHBB 2AEHA 2I1KA 1DDMA 2CODA 2LG1A 2ELBA 4EJNA 4EMOA 2KGXB 1F5XA 2EJ8A 1H4RA 2X18A 2M14A 5JP4A 4MK0A 1P6SA 1U29A 4CYEA 1TJ6A 1QC6A 4WJ7A 5D3XA 1SGHA 2P0DA 2G35A 1V5MA 3ML4A 2RLOA 1IRSA 5J3YA 1V5UA 1X1GA 3MPXA 1X1FA 2RNRB 1WI1A 5KQ4A 2CY5A 4H8SA 3HW2B 1TXDA 3P7ZA 2K2UA 3GYPA 2LYDA 4HAYB 4F7HA 3U8ZA 2I5CA 1Y5OA 1ZSQA 3D8DA 1V5PA 1DDVA 1DDWA 1BAKA 2ZPYA 3DXDA 2EMTA 2H7EA 3TW1A 4IFSA 3TFMA 4HATB 4MY6A 4WSFA 5HE3A 2D10A 5D27A 1PMSA 2DLWA 2LOXA 2D9VA 3RCPA 2YS3A 4ZRKA 1UNRA 4HDQA 1U5GA 5EFXA 5J3TA 1FHXA 2FJLA 1RRPB 1J0WA 1MK7B 1H10A 4MT7A 3EO2A 2D11A 2RGNB 2K2JA 3PVWA 4WVFB 1P3RA 2D4QA 2RVBB 3SYXA 5DI9B 1GC7A 3M1IB 3PVUA 3JV3A 5KCVA 2M38A 4TKNA 1GG3A 3MDBC 1OQNA 2DHKA 2Z0PA 1X05A 2P8VA 1PLSA 3CXBB 4Z2MB 3A8QA 2OQBA 2PZ1A 5CLLB 3LJUX 3UZTA 3X23A 3F5RA 2N23A 1MIXA 1WGQA 4GOUA 3FSSA 1OMWA 5JHGA 2QKLA 4KAXB 3KRWA 3WA0A 1W1HA 2LULA 1XX0A 4KVGB 3VOQA 2EMSA 2D2QA 1FAOA 3OANA 1WVHA 4HHVA 4GMVA 3O96A 1BTNA 1W1DA 2HE7A 1KZGA 4HB2B 4KHAA 3HQCA 5D3VA 5DHAB 2D9ZA 2YRYA 5KQ1A 2MWNB 2Q13A 2D9WA 3ODWA 2YF0A 3F0WA 5D3WA 2ROZB 1FGZA 2W2WA 2E2XA 3ULBA 1X11A 3FM8C 5D3YA 3N7CA 2H7DA 4GMXB 1ZM0A 2XQNM 3ULCA 3AJ4A 5HE0A 1MK9B 1U2BA 1EAZA 2UZSA 4P7IA 3P6AA 1FHOA 1ISNA 5L81A 5LOPB 1RJ2A 1KZ7A 4HAVB 1EVHA 2W2XC 1BTKA 1FOEA 2DFKA 1B55A 2R09A 4HB3B 5GOWB 2DN6A 4A6FB 1XKEA 5FI1A 2YT1A 2D9YA 1M7EA 3GF9A 2CRFA 1EGXA 2UVMA 2NZ8B 1FGYA 2YVCA 3PSCA 2J59M 3CIKA 2L2IA 1TQZA 4XWXA 4EKUA 2OTXA 4F7GA 1UNPA 5C5BA 4BBKA 2RSGA 2LOZA 1PFJA 1V89A 3PVLA 5LONB 1DROA 2EC1A 4Y94A 3U7DA 4YONA 1OY2A 4HB0B 2GCLA 2ROVA 2GJYA 3WYFB 5HE1A 2YS1A 2L1CA 4HAWB 1W1GA 5JHHA 1XODA 3AU4A 3DXCA 1FHWA 2Z0QA 3PZDA 1DYNA 2J0KA 1UNQA 4B6HA 2P0FA 2UZRA 2ADZA 5J3QA 3TVVA 5CLQB 1MPHA 4IOYX 2N0YA 1I7AA 3ODXA 1Q67A 2GCJA 4D0NB 3A8PA 3KY9A 2VRWB 4K17A 3PP2A 2AL6A 1Y19B 2DA0A 1N3HA 1BY1A 2VSZA 1NU2A 2CY4A 2IFSA 2DYQA 3KRXA 1DBHA 1U5EA 1AWEA 1MKEA 2DKQA 1MAIA 2Y8FA 3PG7A 1X86A 3SO6A 4F7UP 5DH9B 1M7RA 2Z0OA 3VIAA 2R0DA 2YSZA 2W2XD 1UPRA 4K2PA 4KHOA 4TYZA 1U5FA 3SNHA 1XCGA 4C0AA 1AQCA 3KSYA 1K5DB 2V76A 1MIZB 4L6EA 2GS0A 2J0MA 2MKRA 5C16A 3T06A 2HTHB 2P0HA 1ZC4B 4HAZB 4A6HA 1NTYA 3ZDTA 3NSUA 3TO1A 4GYVA 2DX5A 3BJIA 2MDXA 4DX8A 2YS5A 1GC6A 2K00A 2NMBA
chains in the Genus database with same CATH superfamily

4HDOA 1LB1A 3A98B 1BWNA 2I1JA 1LW3A 1WGUA 2RUKB 3D8EA 2D9XA 1FB8A 4PQ0A 1NI2A 1WJ1A 2DKPA 2KR0A 3HSAA 4ZRJA 5C79A 3HK0A 3G9WA 5FI0A 5C6RA 4NY0A 2COAA 4IAPA 3NWAA 4GN1A 1MI1A 1WJMA 2I5FA 1V88A 4OT1A 2GUMA 3SV1A 4CHJA 1V61A 3DXEA 1QQGA 2BCJA 1U27A 2DYNA 4Z2NA 2MFQA 4CSQA 4DBBA 1E5WA 4KHBA 4DXAB 4D0OA 1ZYIA 4GZUA 4CHMA 3OHMB 2COCA 2DHJA 4A6KA 2DHIA 2QKMA 4HAUB 3TCAA 3AU5A 1XD4A 4NSWA 4QJ3B 4DX90 1SHCA 2LKOA 3FEHA 1NTVA 4A5KA 3QBVB 3IVFA 3BINA 4YL8A 2Y8GA 2VKIA 3PEGA 3ODOA 1Z87A 4ZRIA 2DTCA 2Z59A 3V5WA 2KR9A 5I2SA 2IYBA 1UPQA 1J19A 5I2MA 1EF1A 2KCJA 2ELAA 5JLJB 4GXBA 1I2HA 2JP2A 3ZVRA 2KIGA 2Z4DA 1UEFA 1ZVRA 4HB4B 1P5TA 3KZ1A 3D8FA 1U5DA 4K2OA 5M4YB 4OSNA 2J0JA 1WG7A 1KI1B 3DCXA 4A6FA 1ZC3B 5C5BB 4HAXB 2CAYA 5DHFB 1XR0B 1K5GB 2DX1A 3SUZA 3GYOA 3QWMA 2KUPA 4GPTB 3QIJA 2COFA 2Y7BA 5DIFB 2YT0A 4K81A 4PNKA 5HE2A 4KHBB 2AEHA 2I1KA 1DDMA 2CODA 2LG1A 2ELBA 4EJNA 4EMOA 2KGXB 1F5XA 2EJ8A 1H4RA 2X18A 2M14A 5JP4A 4MK0A 4QJ5B 1P6SA 1U29A 4CYEA 1TJ6A 1QC6A 4WJ7A 5D3XA 1SGHA 2P0DA 2Z14A 4QJ4B 2G35A 1V5MA 3ML4A 2RLOA 1IRSA 5J3YA 1V5UA 1X1GA 3MPXA 1X1FA 2RNRB 1WI1A 5KQ4A 2CY5A 4H8SA 3HW2B 1TXDA 3P7ZA 4DIXA 2K2UA 3GYPA 2LYDA 4HAYB 4F7HA 3U8ZA 2I5CA 1Y5OA 1ZSQA 3D8DA 1V5PA 1DDVA 1DDWA 1BAKA 2ZPYA 3DXDA 2EMTA 2H7EA 3TW1A 4IFSA 3HIEA 3TFMA 4HATB 4MY6A 4WSFA 5HE3A 2D10A 5D27A 1PMSA 2DLWA 2LOXA 2D9VA 3RCPA 2YS3A 4ZRKA 1UNRA 4HDQA 1U5GA 5EFXA 5J3TA 1FHXA 2FJLA 1RRPB 1J0WA 1MK7B 1H10A 4MT7A 3EO2A 2D11A 2RGNB 2K2JA 3PVWA 4WVFB 2K49A 1P3RA 2D4QA 2RVBB 3SYXA 2FJUB 5DI9B 1GC7A 3M1IB 3PVUA 3JV3A 5KCVA 2M38A 4TKNA 1GG3A 3MDBC 1OQNA 2DHKA 2Z0PA 1X05A 2P8VA 2R2YA 1PLSA 3CXBB 4Z2MB 3A8QA 2OQBA 2PZ1A 5CLLB 3LJUX 3UZTA 3X23A 3F5RA 2N23A 1MIXA 1WGQA 4GOUA 2Z13A 3FSSA 1OMWA 5JHGA 2QKLA 4KAXB 3KRWA 4HSIA 3FVCA 1W1HA 2LULA 3WA0A 1XX0A 4KVGB 3VOQA 5IRSA 2EMSA 2D2QA 1FAOA 3OANA 1WVHA 4HHVA 4GMVA 5LG4B 3O96A 1BTNA 1W1DA 2HE7A 1KZGA 4HB2B 4KHAA 3HQCA 5D3VA 5DHAB 2D9ZA 2YRYA 5KQ1A 2MWNB 2Q13A 2D9WA 2ZKMX 3ODWA 2YF0A 3F0WA 5D3WA 2KUQA 2ROZB 1FGZA 2W2WA 2E2XA 3ULBA 1X11A 3FM8C 5D3YA 3N7CA 2H7DA 4GMXB 1ZM0A 2XQNM 3ULCA 3AJ4A 5HE0A 1MK9B 1U2BA 1EAZA 2UZSA 4P7IA 3P6AA 1FHOA 1ISNA 5L81A 3B77A 5LOPB 1RJ2A 1KZ7A 4HAVB 1EVHA 2W2XC 1BTKA 1FOEA 2DFKA 1B55A 2R09A 4HB3B 5GOWB 2DN6A 4A6FB 1XKEA 5FI1A 2YT1A 2D9YA 1M7EA 3GF9A 2CRFA 1EGXA 2UVMA 2NZ8B 1FGYA 2YVCA 3PSCA 2J59M 3CIKA 2L2IA 1TQZA 4XWXA 4EKUA 2OTXA 4F7GA 1UNPA 3NWDA 5C5BA 4BBKA 2RSGA 2LOZA 2YT2A 1PFJA 1V89A 3PVLA 5LONB 4GNKB 1DROA 2EC1A 4Y94A 3U7DA 4YONA 1OY2A 4HB0B 2GCLA 2ROVA 2GJYA 3WYFB 5HE1A 2YS1A 2L1CA 4HAWB 1W1GA 5JHHA 1XODA 3AU4A 3DXCA 4QXAB 1FHWA 2Z0QA 3PZDA 3A58A 3NWFA 1DYNA 2J0KA 1UNQA 4L1RA 4B6HA 2P0FA 2UZRA 2ADZA 5J3QA 3TVVA 5CLQB 1MPHA 4IOYX 2N0YA 1I7AA 3ODXA 1Q67A 2GCJA 4D0NB 3A8PA 3KY9A 2VRWB 4K17A 3PP2A 2NBVA 2AL6A 1Y19B 2DA0A 1N3HA 1BY1A 2VSZA 1NU2A 1T77A 2CY4A 2IFSA 2DYQA 3KRXA 4D6WA 1DBHA 1U5EA 1AWEA 1MKEA 2DKQA 1MAIA 2Y8FA 3PG7A 1X86A 3SO6A 4F7UP 5DH9B 1M7RA 2Z0OA 3VIAA 2R0DA 2YSZA 3U12A 2W2XD 1UPRA 4K2PA 4KHOA 4TYZA 3NW8A 1U5FA 3SNHA 1XCGA 4C0AA 1AQCA 3KSYA 1K5DB 2V76A 2RRFA 1MIZB 4L6EA 2GS0A 2J0MA 2MKRA 5C16A 3T06A 2HTHB 2P0HA 1ZC4B 4HAZB 2KIEA 4A6HA 1NTYA 3ZDTA 3NSUA 3TO1A 4GYVA 2DX5A 3BJIA 2MDXA 4DX8A 2YS5A 1GC6A 2K8EA 2K00A 2NMBA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4HDO A;  1LB1 A;  3A98 B;  1BWN A;  2I1J A;  1LW3 A;  1WGU A;  2RUK B;  3D8E A;  2D9X A;  1FB8 A;  4PQ0 A;  1NI2 A;  1WJ1 A;  2DKP A;  4ZRJ A;  5C79 A;  3HK0 A;  3G9W A;  5FI0 A;  5C6R A;  4NY0 A;  2COA A;  4IAP A;  4GN1 A;  1WJM A;  2I5F A;  1V88 A;  4CHJ A;  3SV1 A;  1V61 A;  3DXE A;  1QQG A;  2BCJ A;  1U27 A;  2DYN A;  4Z2N A;  2MFQ A;  4DBB A;  1E5W A;  4DXA B;  4D0O A;  4CHM A;  4GZU A;  2COC A;  2DHJ A;  4A6K A;  2DHI A;  2QKM A;  4HAU B;  3TCA A;  3AU5 A;  1XD4 A;  4NSW A;  4DX9 0;  1SHC A;  2LKO A;  3FEH A;  1NTV A;  4A5K A;  3QBV B;  3IVF A;  3BIN A;  4YL8 A;  2Y8G A;  2VKI A;  3PEG A;  3ODO A;  1Z87 A;  4ZRI A;  2DTC A;  3V5W A;  2KR9 A;  2IYB A;  1UPQ A;  1J19 A;  1EF1 A;  2KCJ A;  2ELA A;  5JLJ B;  4GXB A;  1I2H A;  2JP2 A;  3ZVR A;  1UEF A;  1ZVR A;  4HB4 B;  1P5T A;  3KZ1 A;  3D8F A;  1U5D A;  4K2O A;  2J0J A;  1WG7 A;  1KI1 B;  4A6F A;  1ZC3 B;  5C5B B;  4HAX B;  2CAY A;  5DHF B;  1XR0 B;  1K5G B;  2DX1 A;  3SUZ A;  3GYO A;  3QWM A;  2KUP A;  4GPT B;  3QIJ A;  2COF A;  2Y7B A;  5DIF B;  2YT0 A;  4K81 A;  4PNK A;  5HE2 A;  4KHB B;  2AEH A;  2I1K A;  1DDM A;  2COD A;  2LG1 A;  2ELB A;  4EJN A;  4EMO A;  2KGX B;  1F5X A;  2EJ8 A;  1H4R A;  2X18 A;  2M14 A;  5JP4 A;  4MK0 A;  1P6S A;  1U29 A;  4CYE A;  1TJ6 A;  1QC6 A;  4WJ7 A;  5D3X A;  1SGH A;  2P0D A;  2G35 A;  1V5M A;  3ML4 A;  2RLO A;  1IRS A;  5J3Y A;  1V5U A;  1X1G A;  3MPX A;  1X1F A;  2RNR B;  1WI1 A;  5KQ4 A;  2CY5 A;  4H8S A;  3HW2 B;  1TXD A;  3P7Z A;  2K2U A;  3GYP A;  2LYD A;  4HAY B;  4F7H A;  3U8Z A;  2I5C A;  1Y5O A;  1ZSQ A;  3D8D A;  1V5P A;  1DDV A;  1DDW A;  1BAK A;  2ZPY A;  3DXD A;  2EMT A;  2H7E A;  3TW1 A;  4IFS A;  3TFM A;  4HAT B;  4MY6 A;  4WSF A;  5HE3 A;  2D10 A;  5D27 A;  1PMS A;  2DLW A;  2LOX A;  2D9V A;  3RCP A;  2YS3 A;  4ZRK A;  1UNR A;  4HDQ A;  1U5G A;  5EFX A;  5J3T A;  1FHX A;  2FJL A;  1RRP B;  1J0W A;  1MK7 B;  1H10 A;  4MT7 A;  3EO2 A;  2D11 A;  2RGN B;  2K2J A;  3PVW A;  4WVF B;  1P3R A;  2D4Q A;  2RVB B;  3SYX A;  5DI9 B;  1GC7 A;  3M1I B;  3PVU A;  3JV3 A;  5KCV A;  2M38 A;  4TKN A;  1GG3 A;  3MDB C;  1OQN A;  2DHK A;  2Z0P A;  1X05 A;  2P8V A;  1PLS A;  3CXB B;  4Z2M B;  3A8Q A;  2OQB A;  2PZ1 A;  5CLL B;  3LJU X;  3UZT A;  3X23 A;  3F5R A;  2N23 A;  1MIX A;  1WGQ A;  4GOU A;  3FSS A;  1OMW A;  5JHG A;  2QKL A;  4KAX B;  3KRW A;  3WA0 A;  1W1H A;  2LUL A;  1XX0 A;  4KVG B;  3VOQ A;  2EMS A;  2D2Q A;  1FAO A;  3OAN A;  1WVH A;  4HHV A;  4GMV A;  3O96 A;  1BTN A;  1W1D A;  2HE7 A;  1KZG A;  4HB2 B;  4KHA A;  3HQC A;  5D3V A;  5DHA B;  2D9Z A;  2YRY A;  5KQ1 A;  2MWN B;  2Q13 A;  2D9W A;  3ODW A;  2YF0 A;  3F0W A;  5D3W A;  2ROZ B;  1FGZ A;  2W2W A;  2E2X A;  3ULB A;  1X11 A;  3FM8 C;  5D3Y A;  3N7C A;  2H7D A;  4GMX B;  1ZM0 A;  2XQN M;  3ULC A;  3AJ4 A;  5HE0 A;  1MK9 B;  1U2B A;  1EAZ A;  2UZS A;  4P7I A;  3P6A A;  1FHO A;  1ISN A;  5L81 A;  5LOP B;  1RJ2 A;  1KZ7 A;  4HAV B;  1EVH A;  2W2X C;  1BTK A;  1FOE A;  2DFK A;  1B55 A;  2R09 A;  4HB3 B;  5GOW B;  2DN6 A;  4A6F B;  1XKE A;  5FI1 A;  2YT1 A;  2D9Y A;  1M7E A;  3GF9 A;  2CRF A;  1EGX A;  2UVM A;  2NZ8 B;  1FGY A;  2YVC A;  3PSC A;  2J59 M;  3CIK A;  2L2I A;  1TQZ A;  4XWX A;  4EKU A;  2OTX A;  4F7G A;  1UNP A;  5C5B A;  4BBK A;  2RSG A;  2LOZ A;  1PFJ A;  1V89 A;  3PVL A;  5LON B;  1DRO A;  2EC1 A;  4Y94 A;  3U7D A;  4YON A;  1OY2 A;  4HB0 B;  2GCL A;  2ROV A;  2GJY A;  3WYF B;  5HE1 A;  2YS1 A;  2L1C A;  4HAW B;  1W1G A;  5JHH A;  1XOD A;  3AU4 A;  3DXC A;  1FHW A;  2Z0Q A;  3PZD A;  1DYN A;  2J0K A;  1UNQ A;  4B6H A;  2P0F A;  2UZR A;  2ADZ A;  5J3Q A;  3TVV A;  5CLQ B;  1MPH A;  4IOY X;  2N0Y A;  1I7A A;  3ODX A;  1Q67 A;  2GCJ A;  4D0N B;  3A8P A;  3KY9 A;  2VRW B;  4K17 A;  3PP2 A;  2AL6 A;  1Y19 B;  2DA0 A;  1N3H A;  1BY1 A;  2VSZ A;  1NU2 A;  2CY4 A;  2IFS A;  2DYQ A;  3KRX A;  1DBH A;  1U5E A;  1AWE A;  1MKE A;  2DKQ A;  1MAI A;  2Y8F A;  3PG7 A;  1X86 A;  3SO6 A;  4F7U P;  5DH9 B;  1M7R A;  2Z0O A;  3VIA A;  2R0D A;  2YSZ A;  2W2X D;  1UPR A;  4K2P A;  4KHO A;  4TYZ A;  1U5F A;  3SNH A;  1XCG A;  4C0A A;  1AQC A;  3KSY A;  1K5D B;  2V76 A;  1MIZ B;  4L6E A;  2GS0 A;  2J0M A;  2MKR A;  5C16 A;  3T06 A;  2HTH B;  2P0H A;  1ZC4 B;  4HAZ B;  4A6H A;  1NTY A;  3ZDT A;  3NSU A;  3TO1 A;  4GYV A;  2DX5 A;  3BJI A;  2MDX A;  4DX8 A;  2YS5 A;  1GC6 A;  2K00 A;  2NMB A; 
#chains in the Genus database with same CATH topology
 4HDO A;  1LB1 A;  3A98 B;  1BWN A;  2I1J A;  1LW3 A;  1WGU A;  2RUK B;  3D8E A;  2D9X A;  1FB8 A;  4PQ0 A;  1NI2 A;  1WJ1 A;  2DKP A;  2KR0 A;  3HSA A;  4ZRJ A;  5C79 A;  3HK0 A;  3G9W A;  5FI0 A;  5C6R A;  4NY0 A;  2COA A;  4IAP A;  3NWA A;  4GN1 A;  1MI1 A;  1WJM A;  2I5F A;  1V88 A;  4OT1 A;  2GUM A;  3SV1 A;  4CHJ A;  1V61 A;  3DXE A;  1QQG A;  2BCJ A;  1U27 A;  2DYN A;  4Z2N A;  2MFQ A;  4CSQ A;  4DBB A;  1E5W A;  4KHB A;  4DXA B;  4D0O A;  1ZYI A;  4GZU A;  4CHM A;  3OHM B;  2COC A;  2DHJ A;  4A6K A;  2DHI A;  2QKM A;  4HAU B;  3TCA A;  3AU5 A;  1XD4 A;  4NSW A;  4QJ3 B;  4DX9 0;  1SHC A;  2LKO A;  3FEH A;  1NTV A;  4A5K A;  3QBV B;  3IVF A;  3BIN A;  4YL8 A;  2Y8G A;  2VKI A;  3PEG A;  3ODO A;  1Z87 A;  4ZRI A;  2DTC A;  2Z59 A;  3V5W A;  2KR9 A;  5I2S A;  2IYB A;  1UPQ A;  1J19 A;  5I2M A;  1EF1 A;  2KCJ A;  2ELA A;  5JLJ B;  4GXB A;  1I2H A;  2JP2 A;  3ZVR A;  2KIG A;  2Z4D A;  1UEF A;  1ZVR A;  4HB4 B;  1P5T A;  3KZ1 A;  3D8F A;  1U5D A;  4K2O A;  5M4Y B;  4OSN A;  2J0J A;  1WG7 A;  1KI1 B;  3DCX A;  4A6F A;  1ZC3 B;  5C5B B;  4HAX B;  2CAY A;  5DHF B;  1XR0 B;  1K5G B;  2DX1 A;  3SUZ A;  3GYO A;  3QWM A;  2KUP A;  4GPT B;  3QIJ A;  2COF A;  2Y7B A;  5DIF B;  2YT0 A;  4K81 A;  4PNK A;  5HE2 A;  4KHB B;  2AEH A;  2I1K A;  1DDM A;  2COD A;  2LG1 A;  2ELB A;  4EJN A;  4EMO A;  2KGX B;  1F5X A;  2EJ8 A;  1H4R A;  2X18 A;  2M14 A;  5JP4 A;  4MK0 A;  4QJ5 B;  1P6S A;  1U29 A;  4CYE A;  1TJ6 A;  1QC6 A;  4WJ7 A;  5D3X A;  1SGH A;  2P0D A;  2Z14 A;  4QJ4 B;  2G35 A;  1V5M A;  3ML4 A;  2RLO A;  1IRS A;  5J3Y A;  1V5U A;  1X1G A;  3MPX A;  1X1F A;  2RNR B;  1WI1 A;  5KQ4 A;  2CY5 A;  4H8S A;  3HW2 B;  1TXD A;  3P7Z A;  4DIX A;  2K2U A;  3GYP A;  2LYD A;  4HAY B;  4F7H A;  3U8Z A;  2I5C A;  1Y5O A;  1ZSQ A;  3D8D A;  1V5P A;  1DDV A;  1DDW A;  1BAK A;  2ZPY A;  3DXD A;  2EMT A;  2H7E A;  3TW1 A;  4IFS A;  3HIE A;  3TFM A;  4HAT B;  4MY6 A;  4WSF A;  5HE3 A;  2D10 A;  5D27 A;  1PMS A;  2DLW A;  2LOX A;  2D9V A;  3RCP A;  2YS3 A;  4ZRK A;  1UNR A;  4HDQ A;  1U5G A;  5EFX A;  5J3T A;  1FHX A;  2FJL A;  1RRP B;  1J0W A;  1MK7 B;  1H10 A;  4MT7 A;  3EO2 A;  2D11 A;  2RGN B;  2K2J A;  3PVW A;  4WVF B;  2K49 A;  1P3R A;  2D4Q A;  2RVB B;  3SYX A;  2FJU B;  5DI9 B;  1GC7 A;  3M1I B;  3PVU A;  3JV3 A;  5KCV A;  2M38 A;  4TKN A;  1GG3 A;  3MDB C;  1OQN A;  2DHK A;  2Z0P A;  1X05 A;  2P8V A;  2R2Y A;  1PLS A;  3CXB B;  4Z2M B;  3A8Q A;  2OQB A;  2PZ1 A;  5CLL B;  3LJU X;  3UZT A;  3X23 A;  3F5R A;  2N23 A;  1MIX A;  1WGQ A;  4GOU A;  2Z13 A;  3FSS A;  1OMW A;  5JHG A;  2QKL A;  4KAX B;  3KRW A;  4HSI A;  3FVC A;  1W1H A;  2LUL A;  3WA0 A;  1XX0 A;  4KVG B;  3VOQ A;  5IRS A;  2EMS A;  2D2Q A;  1FAO A;  3OAN A;  1WVH A;  4HHV A;  4GMV A;  5LG4 B;  3O96 A;  1BTN A;  1W1D A;  2HE7 A;  1KZG A;  4HB2 B;  4KHA A;  3HQC A;  5D3V A;  5DHA B;  2D9Z A;  2YRY A;  5KQ1 A;  2MWN B;  2Q13 A;  2D9W A;  2ZKM X;  3ODW A;  2YF0 A;  3F0W A;  5D3W A;  2KUQ A;  2ROZ B;  1FGZ A;  2W2W A;  2E2X A;  3ULB A;  1X11 A;  3FM8 C;  5D3Y A;  3N7C A;  2H7D A;  4GMX B;  1ZM0 A;  2XQN M;  3ULC A;  3AJ4 A;  5HE0 A;  1MK9 B;  1U2B A;  1EAZ A;  2UZS A;  4P7I A;  3P6A A;  1FHO A;  1ISN A;  5L81 A;  3B77 A;  5LOP B;  1RJ2 A;  1KZ7 A;  4HAV B;  1EVH A;  2W2X C;  1BTK A;  1FOE A;  2DFK A;  1B55 A;  2R09 A;  4HB3 B;  5GOW B;  2DN6 A;  4A6F B;  1XKE A;  5FI1 A;  2YT1 A;  2D9Y A;  1M7E A;  3GF9 A;  2CRF A;  1EGX A;  2UVM A;  2NZ8 B;  1FGY A;  2YVC A;  3PSC A;  2J59 M;  3CIK A;  2L2I A;  1TQZ A;  4XWX A;  4EKU A;  2OTX A;  4F7G A;  1UNP A;  3NWD A;  5C5B A;  4BBK A;  2RSG A;  2LOZ A;  2YT2 A;  1PFJ A;  1V89 A;  3PVL A;  5LON B;  4GNK B;  1DRO A;  2EC1 A;  4Y94 A;  3U7D A;  4YON A;  1OY2 A;  4HB0 B;  2GCL A;  2ROV A;  2GJY A;  3WYF B;  5HE1 A;  2YS1 A;  2L1C A;  4HAW B;  1W1G A;  5JHH A;  1XOD A;  3AU4 A;  3DXC A;  4QXA B;  1FHW A;  2Z0Q A;  3PZD A;  3A58 A;  3NWF A;  1DYN A;  2J0K A;  1UNQ A;  4L1R A;  4B6H A;  2P0F A;  2UZR A;  2ADZ A;  5J3Q A;  3TVV A;  5CLQ B;  1MPH A;  4IOY X;  2N0Y A;  1I7A A;  3ODX A;  1Q67 A;  2GCJ A;  4D0N B;  3A8P A;  3KY9 A;  2VRW B;  4K17 A;  3PP2 A;  2NBV A;  2AL6 A;  1Y19 B;  2DA0 A;  1N3H A;  1BY1 A;  2VSZ A;  1NU2 A;  1T77 A;  2CY4 A;  2IFS A;  2DYQ A;  3KRX A;  4D6W A;  1DBH A;  1U5E A;  1AWE A;  1MKE A;  2DKQ A;  1MAI A;  2Y8F A;  3PG7 A;  1X86 A;  3SO6 A;  4F7U P;  5DH9 B;  1M7R A;  2Z0O A;  3VIA A;  2R0D A;  2YSZ A;  3U12 A;  2W2X D;  1UPR A;  4K2P A;  4KHO A;  4TYZ A;  3NW8 A;  1U5F A;  3SNH A;  1XCG A;  4C0A A;  1AQC A;  3KSY A;  1K5D B;  2V76 A;  2RRF A;  1MIZ B;  4L6E A;  2GS0 A;  2J0M A;  2MKR A;  5C16 A;  3T06 A;  2HTH B;  2P0H A;  1ZC4 B;  4HAZ B;  2KIE A;  4A6H A;  1NTY A;  3ZDT A;  3NSU A;  3TO1 A;  4GYV A;  2DX5 A;  3BJI A;  2MDX A;  4DX8 A;  2YS5 A;  1GC6 A;  2K8E A;  2K00 A;  2NMB A; 
#chains in the Genus database with same CATH homology
 4HDO A;  1LB1 A;  3A98 B;  1BWN A;  2I1J A;  1LW3 A;  1WGU A;  2RUK B;  3D8E A;  2D9X A;  1FB8 A;  4PQ0 A;  1NI2 A;  1WJ1 A;  2DKP A;  4ZRJ A;  5C79 A;  3HK0 A;  3G9W A;  5FI0 A;  5C6R A;  4NY0 A;  2COA A;  4IAP A;  4GN1 A;  1WJM A;  2I5F A;  1V88 A;  4CHJ A;  3SV1 A;  1V61 A;  3DXE A;  1QQG A;  2BCJ A;  1U27 A;  2DYN A;  4Z2N A;  2MFQ A;  4DBB A;  1E5W A;  4DXA B;  4D0O A;  4CHM A;  4GZU A;  2COC A;  2DHJ A;  4A6K A;  2DHI A;  2QKM A;  4HAU B;  3TCA A;  3AU5 A;  1XD4 A;  4NSW A;  4DX9 0;  1SHC A;  2LKO A;  3FEH A;  1NTV A;  4A5K A;  3QBV B;  3IVF A;  3BIN A;  4YL8 A;  2Y8G A;  2VKI A;  3PEG A;  3ODO A;  1Z87 A;  4ZRI A;  2DTC A;  3V5W A;  2KR9 A;  2IYB A;  1UPQ A;  1J19 A;  1EF1 A;  2KCJ A;  2ELA A;  5JLJ B;  4GXB A;  1I2H A;  2JP2 A;  3ZVR A;  1UEF A;  1ZVR A;  4HB4 B;  1P5T A;  3KZ1 A;  3D8F A;  1U5D A;  4K2O A;  2J0J A;  1WG7 A;  1KI1 B;  4A6F A;  1ZC3 B;  5C5B B;  4HAX B;  2CAY A;  5DHF B;  1XR0 B;  1K5G B;  2DX1 A;  3SUZ A;  3GYO A;  3QWM A;  2KUP A;  4GPT B;  3QIJ A;  2COF A;  2Y7B A;  5DIF B;  2YT0 A;  4K81 A;  4PNK A;  5HE2 A;  4KHB B;  2AEH A;  2I1K A;  1DDM A;  2COD A;  2LG1 A;  2ELB A;  4EJN A;  4EMO A;  2KGX B;  1F5X A;  2EJ8 A;  1H4R A;  2X18 A;  2M14 A;  5JP4 A;  4MK0 A;  1P6S A;  1U29 A;  4CYE A;  1TJ6 A;  1QC6 A;  4WJ7 A;  5D3X A;  1SGH A;  2P0D A;  2G35 A;  1V5M A;  3ML4 A;  2RLO A;  1IRS A;  5J3Y A;  1V5U A;  1X1G A;  3MPX A;  1X1F A;  2RNR B;  1WI1 A;  5KQ4 A;  2CY5 A;  4H8S A;  3HW2 B;  1TXD A;  3P7Z A;  2K2U A;  3GYP A;  2LYD A;  4HAY B;  4F7H A;  3U8Z A;  2I5C A;  1Y5O A;  1ZSQ A;  3D8D A;  1V5P A;  1DDV A;  1DDW A;  1BAK A;  2ZPY A;  3DXD A;  2EMT A;  2H7E A;  3TW1 A;  4IFS A;  3TFM A;  4HAT B;  4MY6 A;  4WSF A;  5HE3 A;  2D10 A;  5D27 A;  1PMS A;  2DLW A;  2LOX A;  2D9V A;  3RCP A;  2YS3 A;  4ZRK A;  1UNR A;  4HDQ A;  1U5G A;  5EFX A;  5J3T A;  1FHX A;  2FJL A;  1RRP B;  1J0W A;  1MK7 B;  1H10 A;  4MT7 A;  3EO2 A;  2D11 A;  2RGN B;  2K2J A;  3PVW A;  4WVF B;  1P3R A;  2D4Q A;  2RVB B;  3SYX A;  5DI9 B;  1GC7 A;  3M1I B;  3PVU A;  3JV3 A;  5KCV A;  2M38 A;  4TKN A;  1GG3 A;  3MDB C;  1OQN A;  2DHK A;  2Z0P A;  1X05 A;  2P8V A;  1PLS A;  3CXB B;  4Z2M B;  3A8Q A;  2OQB A;  2PZ1 A;  5CLL B;  3LJU X;  3UZT A;  3X23 A;  3F5R A;  2N23 A;  1MIX A;  1WGQ A;  4GOU A;  3FSS A;  1OMW A;  5JHG A;  2QKL A;  4KAX B;  3KRW A;  3WA0 A;  1W1H A;  2LUL A;  1XX0 A;  4KVG B;  3VOQ A;  2EMS A;  2D2Q A;  1FAO A;  3OAN A;  1WVH A;  4HHV A;  4GMV A;  3O96 A;  1BTN A;  1W1D A;  2HE7 A;  1KZG A;  4HB2 B;  4KHA A;  3HQC A;  5D3V A;  5DHA B;  2D9Z A;  2YRY A;  5KQ1 A;  2MWN B;  2Q13 A;  2D9W A;  3ODW A;  2YF0 A;  3F0W A;  5D3W A;  2ROZ B;  1FGZ A;  2W2W A;  2E2X A;  3ULB A;  1X11 A;  3FM8 C;  5D3Y A;  3N7C A;  2H7D A;  4GMX B;  1ZM0 A;  2XQN M;  3ULC A;  3AJ4 A;  5HE0 A;  1MK9 B;  1U2B A;  1EAZ A;  2UZS A;  4P7I A;  3P6A A;  1FHO A;  1ISN A;  5L81 A;  5LOP B;  1RJ2 A;  1KZ7 A;  4HAV B;  1EVH A;  2W2X C;  1BTK A;  1FOE A;  2DFK A;  1B55 A;  2R09 A;  4HB3 B;  5GOW B;  2DN6 A;  4A6F B;  1XKE A;  5FI1 A;  2YT1 A;  2D9Y A;  1M7E A;  3GF9 A;  2CRF A;  1EGX A;  2UVM A;  2NZ8 B;  1FGY A;  2YVC A;  3PSC A;  2J59 M;  3CIK A;  2L2I A;  1TQZ A;  4XWX A;  4EKU A;  2OTX A;  4F7G A;  1UNP A;  5C5B A;  4BBK A;  2RSG A;  2LOZ A;  1PFJ A;  1V89 A;  3PVL A;  5LON B;  1DRO A;  2EC1 A;  4Y94 A;  3U7D A;  4YON A;  1OY2 A;  4HB0 B;  2GCL A;  2ROV A;  2GJY A;  3WYF B;  5HE1 A;  2YS1 A;  2L1C A;  4HAW B;  1W1G A;  5JHH A;  1XOD A;  3AU4 A;  3DXC A;  1FHW A;  2Z0Q A;  3PZD A;  1DYN A;  2J0K A;  1UNQ A;  4B6H A;  2P0F A;  2UZR A;  2ADZ A;  5J3Q A;  3TVV A;  5CLQ B;  1MPH A;  4IOY X;  2N0Y A;  1I7A A;  3ODX A;  1Q67 A;  2GCJ A;  4D0N B;  3A8P A;  3KY9 A;  2VRW B;  4K17 A;  3PP2 A;  2AL6 A;  1Y19 B;  2DA0 A;  1N3H A;  1BY1 A;  2VSZ A;  1NU2 A;  2CY4 A;  2IFS A;  2DYQ A;  3KRX A;  1DBH A;  1U5E A;  1AWE A;  1MKE A;  2DKQ A;  1MAI A;  2Y8F A;  3PG7 A;  1X86 A;  3SO6 A;  4F7U P;  5DH9 B;  1M7R A;  2Z0O A;  3VIA A;  2R0D A;  2YSZ A;  2W2X D;  1UPR A;  4K2P A;  4KHO A;  4TYZ A;  1U5F A;  3SNH A;  1XCG A;  4C0A A;  1AQC A;  3KSY A;  1K5D B;  2V76 A;  1MIZ B;  4L6E A;  2GS0 A;  2J0M A;  2MKR A;  5C16 A;  3T06 A;  2HTH B;  2P0H A;  1ZC4 B;  4HAZ B;  4A6H A;  1NTY A;  3ZDT A;  3NSU A;  3TO1 A;  4GYV A;  2DX5 A;  3BJI A;  2MDX A;  4DX8 A;  2YS5 A;  1GC6 A;  2K00 A;  2NMB A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

3T06A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations